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Keywords:

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EiPF+ AFF+ IQ+ ?KF+ BGQAM+ Beqegjkheio

Pénphé Dmaiçadn

Le contrôle de la reproduction est médié par un réseau hypothalamique qui régule la sécrétion de la Gonadotropin Releasing Hormone (GnRH). Les neurones à GnRH naissent dans la placode olfactive et migrent vers le cerveau le long des axones vomeronasaux et terminaux au cours du développement embryonnaire. Des perturbations dans le développement ou dans la sécrétion de GnRH sont associées à l'hypogonadisme hypogonadotrope congénital (CHH) et au syndrome de Kallmann (KS). Ce travail révèle que l'hormone anti-Müllerienne (AMH), impliquée dans le développement urogénital masculin, est mutée dans les cohortes de patients atteints de CHH et KS et suggère que la perturbation de la signalisation de l'AMH pourrait contribuer à ces troubles à travers la régulation de la migration des neurones à GnRH.

L'imagerie de foetus et embryons humains entiers à résolution cellulaire a dévoilé de nouveaux concepts sur le développement embryonnaire humain, permettant d'établir, pour la première fois une véritable représentation des neurones dans leur contexte natal, in vivo, ainsi que de mettre en évidence des caractéristiques inconnues sur le développement sexuellement dimorphique du système urogénital chez l'homme. Cette approche a révélé que non seulement le nombre de neurones à GnRH chez l'homme était significativement plus élevé que celui estimé auparavant, mais aussi que ces derniers migrent vers plusieurs régions du cerveau extra-hypothalamique, Leur présence dans ces régions soulève l'hypothèse qu'ils pourraient exercer des rôles non-reproductifs, créant de nouvelles pistes pour la recherche sur les fonctions du système GnRH dans les processus cognitifs, comportementaux et physiologiques.

Boba Qléa4

GnRH, CHH, KS, AMH, DISCO, Développement

Pénphé Dmaiçadn Qp]noaiodeg

Tout au long de l'histoire, le désir des scientifiques de comprendre la physiologie et la maladie en étudiant minutieusement les caractéristiques anatomiques a toujours été confronté à une contrainte insoluble: ils ne peuvent pas simplement voir à travers les tissus. La dissection a donc été le mode opératoire des anatomistes: des études pionnières de Galen, aux biologistes modernes qui sectionnent systématiquement les tissus pour étiqueter des structures pour une analyse microscopique.

Bien que ces méthodes aient formé une richesse de connaissances reliant la forme anatomique à la fonction, elles sont intrinsèquement erronées en raison d'une appréciation en 3 dimensions des structures perdues. Cela a été particulièrement problématique pour l'étude des processus de développement, où les structures évoluent continuellement et, par conséquent, une visualisation précise a été impossible à réaliser grâce aux méthodes traditionnelles et aux atlas anatomiques. De plus, la majorité de nos connaissances sur les systèmes de développement découlent d'études menées dans le poulet et le poisson zèbre; qui, bien que d'excellents modèles pour étudier ces processus, peuvent présenter des différences significatives par rapport aux humains. Associée aux difficultés d'accès aux tissus, notre compréhension du développement humain a progressé peut-être le processus biologique le plus lent depuis les années 1930; alors que dans certains cas, des observations de vertébrés inférieurs ont été appliquées de manière erronée à l'homme, ce qui a donné lieu à de fortes contradictions dans la littérature existante.

Sans une bonne compréhension du développement physiologique, nous n'avons pas les connaissances fondamentales requises pour que les cliniciens et les chercheurs s'attaquent aux syndromes de développement qui influèrent une grave charge de santé et un fardeau émotionnel pour la société. Les progrès récents dans les techniques d'imagerie in vivo non invasives, ont été très prometteurs pour détecter des anomalies congénitales et fournir des informations sur les caractéristiques topologiques brutes du développement foetal; cependant, ils manquent d'une résolution suffisante pour informer les biologistes du développement des caractéristiques actuellement inconnues de l'organogenèse. Cela a récemment été particulièrement souligné par la récente augmentation des infections par le virus Zika et les effets préjudiciables sur le développement céphalique.

La première méthode pour y remédier par des tissus «éclaircis optiquement» a été proposée et développée par l'anatomiste allemand Werner Spalteholtz; en fonction de la déshydratation des tissus afin d'obtenir une correspondance de l'indice de réfraction. Plus récemment, avec les progrès de la microscopie de fluorescence en feuille légère (LSFM), une variété de techniques de compensation optique ont été développées qui ont tous pour résultat un clouage de tissus par des principes similaires, malgré les différences sous-jacentes dans leurs approches chimiques. Chaque méthodologie a ses avantages et inconvénients respectifs, conçue pour répondre de manière idéale à différentes questions biologiques.

L'un de ces protocoles, 3DISCO, basé sur la capacité des solvants organiques spécifiques à se déshydrater, à solvater les lipides et à provoquer une correspondance de l'indice de réfraction, entraîne également une réduction de 50% du volume total du tissu. Ces propriétés, en conjonction avec sa compatibilité avec une large gamme d'anticorps et la préservation du signal de fluorescence, signifient qu'il est idéal pour examiner le développement de plusieurs systèmes corporels pendant le premier trimestre du développement humain.

Au cours de l'embryogenèse, tous les processus de développement précoce continuent selon une trajectoire unique, indépendamment du sexe génétique, avec la différenciation des gonades embryonnaires formant la première signature moléculaire qui provoque une différenciation sexuelle.

Avant l'expression des facteurs des testicules, la gonade existe dans un état bi potentiel, formé de deux conduits appariés, le conduit Wolffien capable de se différencier par le conduit masculin et Müllerian (MD) capable de former le tractus reproducteur féminin. Chez les mammifères, la présence de la région déterminant le sexe sur le gène Y (SRY) est nécessaire et suffisante pour déclencher une différenciation sexuelle de la gonade bi potentielle pour former des structures reproductrices masculines. L'expression SRY déclenche une cascade moléculaire impliquant l'expression d'un gène homologue 10 (SOX10) et une expression du gène anti-Müllerian Hormone (AMH) liée à SRY à partir du testicule embryonnaire. AMH est un membre de la superfamille du facteur de croissance transformant-β (TGFß) qui initie la transition épithéliale-mésenchymateuse en régulant la régression du MD. Cette signalisation est régulée dans une fenêtre temporelle stricte, à l'extérieur de laquelle le MD est horriblement insensible et la régression ne peut pas se produire. En outre, les mutations génétiques dans l'AMH ou son récepteur AMHR2 entraînent la rétention des structures de MD à l'âge adulte dans les mâles 46XY, autrement normalement virilisés, ce qui provoque le syndrome du conduit de Müllerian persistant du syndrome d'infertilité (PMDS). Bien que ce processus par lequel un facteur testiculaire autre que la testostérone ait été responsable de la régression MG a été identifié en 1974 par le scientifique français Alfred Jost travaillant sur des lapins, la plupart de nos connaissances sur le processus ont ensuite été menées dans des modèles de rongeurs, en établissant une approche globale image qui doit encore être confirmée chez les humains.

L'acquisition de la compétence en matière de reproduction dépend du bon développement de plusieurs systèmes corporels distincts des gonades -l'hypophyse et le cerveau; qui forment ensemble l'axe hypothalamo hypophysaire gonadique. La communication entre chaque composante de l'axe est relayée par des messagers hormonaux sécrétés dans le sang, assurant que les fonctions de chacun et les sécrétions sont maintenues autour des points de consigne physiologiques. Bien que de nombreuses entrées externes et internes régulent la fertilité en fonction des besoins spécifiques de l'espèce, dans tous les vertébrés, les intrants convergent éventuellement sur une seule population de neurones qui synthétisent et sécrètent l'hormone de décapeptide gonadotrophine. Ces neurones forment un réseau neuronal dispersé avec des corps cellulaires généralement trouvés dispersés dans un continuum bilatéral de la bande dorsale de Broca à l'hypothalamus antérieur, typiquement entre environ 800 cellules chez la souris et plusieurs milliers chez les humains. Ces neurones envoient des projections à la zone externe de l'éminence médiane où ils sécrètent la GnRH dans le plexus primaire spécialisé de la circulation du porteur de l'hypothalamo-hypophysaire, pour être administré à l'hypophyse antérieure où elle régule la synthèse et la sécrétion des hormones gonadotrophines à l'hormone lutéinisante (LH) et l'hormone folliculostimulante (FSH).

L'invalidation génétique de la GnRH, comme dans la souris hypogonadique naturelle (Hpg) rend les animaux stériles, la fertilité pouvant être restaurée par transplantation de neurones GnRH immortalisés ou de cellules du cerveau embryonnaire contenant des neurones GnRH. Une perte de GnRH chez l'homme est typiquement congénitale (bien que dans de rares cas elle puisse être acquise) et forme un groupe de syndromes d'infertilité, collectivement connus sous le nom d'hypogonadismes hypogonadotropes congénitaux (CHH). Le séquençage génomique de plusieurs cohortes de CHH a révélé que plusieurs familles de gènes peuvent générer l'état et, actuellement, environ 50% des cas cliniques peuvent s'expliquer par ces mutations connues.

Les neurones de la GnRH sont inhabituels dans la mesure où ils naissent dans le compartiment nasal et doivent migrer le long d'une collection de fibres nerveuses olfactives et terminales à travers la plaque cribriforme pour entrer dans le cerveau et cibler l'hypothalamus. Bien que ce processus semble particulier, car toutes les autres hormones de libération hypophysiotropes sont nées dans l'hypothalamus en développement, elles sont à la base d'une relation évolutive profonde entre la reproduction et l'olfaction.

Ceci est souligné par un autre syndrome d'infertilité humaine connu sous le nom de syndrome de Kallmann (KS) qui associe CHH et anosmie et les résultats en raison de la rupture de la migration embryonnaire des fibres olfactives qui servent de guide pour les neurones GnRH pendant le développement.

Bien que le comportement migratoire des cellules olfactives et de la GnRH ait été décrit initialement il y a près de 30 ans, une description complète et une cartographie anatomique de ces cellules dans l'embryologie humaine, en raison de raisons socioculturelles, religieuses ou morales, manquent encore. À l'heure actuelle, environ seulement 50% des cas cliniques de CHH ont expliqué des causes génétiques, la proportion restante étant attribuée à des mutations génétiques inconnues. Les données récentes provenant de notre laboratoire ont identifié AMH comme un stimulant puissant de la libération de GnRH, déclenchant la libération de LH in vivo et augmentant l'activité de tir électrique des neurones de GnRH. Les auteurs ont également démontré que le récepteur AMH AMHR2 est exprimé par la migration des neurones GnRH pendant le développement chez les souris et les humains.

Les principaux objectifs de ce travail sont donc:

-Appliquer les progrès récents dans le domaine de la décoloration des tissus et de l'immunocoloration totale pour caractériser le développement des systèmes nerveux périphérique humain et urogénital pendant le premier trimestre de gestation -Utiliser ces techniques en combinaison avec des méthodes histologiques traditionnelles pour fournir la première description détaillée de la migration de la GnRH dans le développement humain et créer un atlas 3D de leur répartition spatiale au début du développement -Caractériser un rôle potentiel de la signalisation hormonale anti-Müllerienne dans le développement du système GnRH et sa contribution potentielle à la CHH.

La génération d'une cartographie cellulaire et moléculaire précise de l'embryon humain est essentielle pour comprendre les mécanismes de l'organogenèse dans des conditions normales et pathologiques.

Ici, nous avons combiné l'immunocoloration intégrale, le décapage 3DISCO et l'imagerie feuille-lumière pour faire les premières étapes vers la construction d'une carte cellulaire tridimensionnelle du développement humain pendant le premier trimestre de gestation. Nous fournissons des images 3D à une résolution sans précédent des différents systèmes de développement, y compris le système nerveux périphérique et le système urogénital. Nous présentons des preuves d'une vascularisation différentielle des voies génitales masculine et féminine associée à la détermination du sexe. Ce travail ouvre la voie à un atlas de référence cellulaire et moléculaire des cellules humaines qui est essentiel à la compréhension des troubles du développement humain.

En outre, les résultats décrits dans les chapitres précédents aident à élucider plusieurs aspects morphologiques et fonctionnels importants du développement du système GnRH-1 chez les souris et les humains. Nous fournissons la première preuve de l'immunoréactivité de la GnRH au CS16, environ 39 jours de gestation, ce qui confirme que la naissance de cette population survient plusieurs jours plus tôt que précédemment. Notre quantification du nombre total de cellules GnRH présentes au cours du développement humain est le premier de son genre et suggère une augmentation rapide de la taille de la population entre les 39ème et 44ème jours de gestation, passant de 50 cellules à une moyenne d'environ 8 000 cellules quelques jours plus tard. Ce nombre est très susceptible d'être une représentation précise de la population totale, car l'ARNm de GnRH-1 a montré un profil d'expression très similaire et un nombre similaire dans les cerveaux adultes post-mortem.

La confirmation des résultats signalés il y a 20 ans dans les macaques rhésus d'une voie migratoire dorsale, conduisant à des populations extra-hypothalamiques de neurones exprimant GnRH ouvre la voie à de nouvelles découvertes scientifiques et cliniques sur le rôle de l'expression et la libération de la GnRH dans la physiologie de la reproduction humaine, le comportement olfactif et les processus cognitifs.

Longtemps considéré comme une hormone purement gonadique, nous rapportons que l'hormone antimüllerienne s'exprime lors d'un développement embryonnaire précoce le long de la voie migratrice de GnRH et qu'elle régule la motilité de la GnRH par l'intermédiaire de l'hétérodimérisation AMHR2 / BMPR1b. L'invalidation de la signalisation AMH in vivo entraîne un développement défectueux du système olfactif périphérique et une migration embryonnaire altérée des cellules GnRH vers le cerveau antérieur basal, ce qui entraîne une réduction significative de la taille de la population de GnRH à l'âge adulte et un phénotype de type KS.

Ces nouveaux rapports sont étayés par un séquençage exhaustif d'une cohorte de 70 KS et de ((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((( ,0-8onQlcaWona ((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((( , (((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((( ,01 6CC:M 1 (((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((( ,3/ 8rOnWOl nSrdSa (( ((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((( ,3

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Rcdn d_ea menpmaace_ di oce 084/'n an a ojkdc ja bmeao dioemeno+ a kemdj_ rcei hait ja oce _dncjqemden ocao ncake iepmjncdeice an re fijr do oj_at reme ha_e-Acehdcag iepmjomainhdnndji ao hjojiepmji ntiaknen 'Bmjf eo ag-+ 0841(+ oce djidc ]andn ajm acodji kjoeiodag kmjkabaodji 'Fj_bfdi % Fpsget+ 0841(+ oce admno qdnpagdnaodji ja oce ntiakne ]t egecomji hdcmjncjkt 'Naga_e % Nagat+ 0843( ai_ oce admno omacem ja iepmjiag kaocratn 'Lapoa % Etbas+ 0843( agg dhhe_daoegt kmece_e_ Eejaamet Fammdn' diagpeiodag Lepmag cjiomjg ja oce Ndopdoamt Egai_ '0844(-Feme Fammdn jpogdie_ ocmee fet kmjkemoden ocao a ctkjkctndjomjkdc megeandib aacojm ncjpg_ naodnat di jm_em ajm oce ctkjocagahpn oj mebpgaoe ctkjkctneag apicodji9 , Rce np]noaice hpno ]e kmeneio di oce ctkjkctneag kjmoag qennegn ao a cjiceiomaodji bmeaoem ocai oce ntnoehdc cdmcpgaodji , Rce cjiceiomaodji rdocdi oce kjmoag cdmcpgaodji ncjpg_ qamt di accjm_aice rdoc egecomdcag acodqaodji ja ctkjocagahdc iemqen , Rce acodqdot ja oce a_eijctkjkctndn ncjpg_ cjmmegaoe rdoc ocene qamtdib cjiceiomaodjin Rj apggt naodnat ja agg Fammdn' cmdoemda rjpg_ melpdme oreiot teamn ja eskemdheioaodji+ rdoc bjia_jomjkdi megeandib cjmhjie 'EiPF( ]ecjhdib oce admno apggt mecjbidne_ ctkjocagahdc megeandib aacojm 'Ddif+ 0865: Qamfam eo ag-+ 0865(+ kgacdib do ceiomaggt an oce cjiomjggem ja oce ctkjocagahj,ctkjkctneag,bjia_ag 'FNE( asdn (HSQbWon 1(.(-;WUcrS ,( 8lOaaWQOl RrOeWnUa oT bVS dSnbrOl acrTOQS oT bVS PrOWn rSlObWnU bo bVS ORSnoVgpopVgaWa( Tenagdpn' mekmeneioaodji ja oce diapi_d]pgph+ _ekdcodib a cpk neo pkmdbco 'mekmeneiodib oce ctkjocagahpn( ocmjpbc rcdcc do ran ocjpbco ocao oce kdopdoa ja oce ]madi ran cammde_ oj oce a_eijckjkctndn-Rce necji_ _mardib dggpnomaoen oce meoe hdma]dge+ oce diomdcaoe ]maiccdib ja ]gjj_ qennegn neei aaoem cameapg _dnnecodji ja oce qeiomag npmaace ja oce ]madi-Pea-Qapi_emn % M'Kagget+ 084/+ k081(, 9SdSlopmSnb oT bVS VgpobVOlOmcaRce eqjgpodjiamt jmdbdin ja oce ctkjocagahpn cai ]e omace_ oj oce hpmft raoemn ocao ame cjhe oj oce gano cjhhji aicenojm ja qemoe]maoen+ agden ai_ rjmhn-Rce aiiegd_ rjmh Ngaotiemedn _phemdgdd ncamen aghjno d_eiodcag _eqegjkheio ja PD,ahd_e ai_ qanjojcdi 'a cjmhjie ocao ncamen a gambegt ndhdgam apicodjiag mjge oj qanjkmenndi ai_ jstojcdi di mebpgaodib mekmj_pcodji ai_ raoem ]agaice( iepmjin rdoc ue]maadnc _aidj memdj 'Rennham,Pad]ge eo ag-+ 1//6(+ npbbenodib ocao ocene iepmjin ocao rjpg_ eqeiopaggt cgpnoem ojbeocem oj ajmh oce qemoe]maoe ctkjocagahpn+ hat caqe agmea_t ]eei kmeneio di Sm]dgaoemda 'oce ctkjoceodcag gano cjhhji aicenojm ja aidhagn kjnnenndib a ]dgaoemag nthheomt(-Dpmocemhjme+ ctkjocagahdc megaoe_ iepmjkekod_en caqe ]eei d_eiodade_ di baibgdjin ja gjrem eqjgpodjiamt aidhagn npcc an cjmagn ai_ cgahn 'Rrai eo ag-+ 1//5: Rafataiabd ai_ Miafa+ 1/0/( cjiadmhdib a qemt aicdeio eqjgpodjiamt jmdbdi-Benkdoe don j]qdjpn dhkjmoaice oj kctndjgjbt an a rcjge+ nop_t dioj oce _eqegjkheio ja oce ctkjocagahpn gabn regg ]ecdi_ meneamcc dioj jocem+ hjme eandgt nebheioe_ mebdjin ja oce ]madi npcc an oce cdkkjcahkpn jm ceme]eggph-Udgceh Fdn+ oce ajpi_em ja oce ojkjgjbdcag eh]mtjgjbdc nccjjg ja ocjpbco ©Ciordcfgpibnheccaidf" cjdie_ oce oemh ctkjocagahpn di cdn rjmf ji oce _eqegjkheio ja oce cphai ]madi 'Fdn+ 0782a+ 0782](+ cjreqem+ don _eqegjkheio nodgg cjiodipen oj ]e ai acodqe adeg_ ja meneamcc-Rrj hadi nccjjgn ja ocjpbco caqe _jhdiaoe_ jpm pi_emnoai_dib ja ctkjocagahdc eh]mtjgjbt ndice oce odhe ja Fdn+ rdoc oce hjno kjkpgam+ oce 'cjgphiam _deicekcagdc hj_eg' ja Femmdcf '080/( 'gambegt ]ane_ ji rjmf di ccdcf eh]mtjn(+ meceiogt aaggdib jpo ja aaqjpm an oce akkgdcaodji ja hjme njkcdnodcaoe_ ojjgn+ ai_ np]noaiodag accmpag ja _aoa can ge_ oj oce me, a_jkodji ja oce 'kmjnjhemdc hj_eg' ja ]madi _eqegjkheio 'meceiogt pk_aoe_ ]t Npeggen % Pp]einoedi+ 1/04(-Gi_ee_+ pndib a beijamccdoecopmag akkmjacc+ Bjhíibpeu ai_ cjggeabpen '1/04( d_eiodade_ ncame_ beieodc omadon ]eoreei mekodgen ai_ ahkcd]dain+ cdbcgdbcodib ai dhkjmoaio hdgenojie di oce aiahidjoe.ahidjoe omaindodji: rcdgno a apmocem nop_t dioj oce iepmj_eqegjkheio ja oce cao ncamf Qctgdjmcdipn caidcpga npkkjmoe_ a kmjnjhemdc _eqegjkheioag amccdoecopme ja oce ctkjocagahpn 'Qaiojn,Bpmái eo ag-+ 1/04( ai_ hafdib do gdfegt ocao oce kmjkjne_ np]_dqdndjin ame aicenomag oj eare_ qemoe]maoen-Rce hj_eg kmjkjnen ocao oce ctkjocagahpn jmdbdiaoen an oce mjnomaghjno kamo ja oce iepmag op]e+ ndice oce _eqegjkheioag ajme]madi geiboc asdn ei_n di oce oemhdiag ragg ja oce ctkjocagahpn-Rce iepmag op]e donega dn a _emdqaodqe ja oce _jmnag ecoj_emh ocao dn nkecdade_ oj ]ecjhe iepmag ecoj_emh 'ajmhdib oce iepmag kgaoe( _pmdib oce ocdm_ reef ja cphai benoaodji-Go ncjpg_ agnj ]e mecjbidne_ ao ocdn kjdio ocao aijocem ecoj_emhag _emdqaodqe+ oce iepmag cmeno+ dn _dnodico amjh oce iepmag op]e+ ajmhdib ao oce ndoe ja _jmnag cgjnpme ja oce op]e ai_ bdqen mdne oj neqemag dhkjmoaio cegg gdieaben dicgp_dib oce kemdkcemag iemqjpn ntnoeh 'dicgp_dib iepmjbgdag ceggn( an regg an oce _eiodie ja oce oeeoc ';WUcrS -(-?n oce iepmag op]e apnen+ oce ]madi ai_ nkdiag cjm_ ame mecjbidna]ge ai_ oce ]madi ]ecjhen np]_dqd_e_ dioj a ajme]madi 'kmjneicekcagji(+ hd_]madi 'heneicekcagji( ai_ cdi_]madi 'mcjh]eicekcagji( ';WUcrS .(-Bt oce ei_ ja oce adaoc reef oce kmjneicekcagji ]ecjhen apmocem np]_dqd_e_ oj ajmh oce oegeicekcagji ai_ _deicekcagji 'Kjjme % Nemnap_+ 0882 -Beqegjkheioag ]djgjbt+ 5 oc e_dodji+ Q-Edg]emo(-Lepmjbeiendn di oce iepmag op]e ]ebdin di oce qeiomag cdi_]madi ]ecdi_ oce cekcagdc agespme+ rdoc oce iepmjbeidc ujie npmmjpi_dib oce qeiomdcge-Gi oce cphai 'Edg]emo+ 0824( ai_ hjpne 'Amjdudem eo ag-+ 1/00(+ iepmjbeiendn ]ebdin di a cjgphi ja ceggn meaemme_ oj ]t Edg]emo an oce 'cegg cjm_'-Djggjrdib iepmjbeiendn+ iepmjiag hdbmaodji dn enneiodag oj oce cjmmeco _eqegjkheio ja oce iemqjpn ntnoeh ai_ can ]eei ncjri oj jccpm ocmjpbc orj _dnodico kmjcennen-Pa_dag hdbmaodji dn oce kmdicdkge hj_e ja iepmjiag hdbmaodji di oce _eqegjkdib ]madi ai_ jccpmn agjib a ncaaajg_ ja ma_dag bgdag cegg ceggn qda cjhkges cegg,cegg dioemacodjin oj _dmeco oce kjndodjidib ja iepmjin ai_ dn menkjind]ge ajm oce haejmdot ja didodag cdnojbeiendn ja iepmag op]e,_emdqe_ ]madi mebdjin 'Neamghai eo ag-+ 0887: Pafdc+ 088/(-Gi cjiomano+ oaibeiodag hdbmaodji jccpmn kemkei_dcpgam oj oce _dmecodji ja ma_dag hdbmaodji ai_ _ekei_n ji oce dioemacodji ja iepmjin rdoc bma_deion ja _daapnd]ge hjgecpgen+ ocao aco an ccehjaoomacoaion ai_ mekeggeion 'Neamghai eo ag-+ 0887(-Rcdn cegg cjm_ bdqen mdne oj oce admno beiemaoe_ ctkjocagahdc iepmjin ocao rdgg pgodhaoegt ajmh oce kjno,ccdanhaodc gaoemag ctkjocagahpn ai_ dicgp_e KAF eskmenndib ceggn 'Amjdudem eo ag-+ 1/00(-Lepmjbeiendn di oce ctkjocagahpn dn _encmd]e_ an diqjgqdib ocmee noaben9 ai eamgt noabe ocao kmj_pcen jigt oce gaoemag ujie: a necji_ ocao dn cjicjhdoaio oj iepmjbeiendn di oce oegeicekcagji ai_ kmj_pcen iepmjin di agg ctkjocagahdc gjibdop_diag ujien+ ]po hjnogt oce he_dag: ai_ a gaoe ocdm_ noabe ocao cjicemin hadigt kemdqeiomdcpgam ujie iepmjin-Gioemenodibgt neqemag nop_den caqe ajpi_ ai dhkjmoaio gaoemag,he_dag hdbmaodji kaooemi di oce _eqegjkdib ctkjocagahpn ';WUcrS /( 'Amjudem eo ag-+ 1/04(+ ]ebdiidib nompcopmag jmbaidnaodji ao C00 di maon+ rdoc oce jmbaidnaodji ja oce ctkjocagahpn kmjkem cjhkgeoe_ ]t C05-Rce ctkjocagahpn akkeamn oj caqe ai diomdindc _jmnag.qeiomag kaooemidib cjindnoeio rdoc oce agam+ ]anag ai_ agjjm kgaoe oemmdojmden ja oce _eqegjkdib iepmag op]e+ rcdgno aioemdjm.kjnoemdjm ujien akkeam oj ]e jmbaidue_ accjm_dib oj gjcag eiqdmjiheioag ndbiagn 'Iakndhagd eo ag-+ 1//3: Kpocp eo ag-+ 1/05(-Kjmagen,Begba_j ai_ cjggeabpen '1/03( ccamacoemdne_ kmjbeidojm _jhadin di oce eamgt ctkjocagahdc qeiomdcpgam ujie ja oce hjpne+ hakkdib oce hdbmaodji ja kekod_e,eskmenndib iepmjiag np]kjkpgaodjin oj ocedm adiag neoogdib kgace-Rce apocjmn ajpi_ diomdcaoe oaibeiodag ai_ ma_dag hdbmaodji mjpoen an regg an a cjind_ema]ge _ebmee ja dioemhdsdib ]eoreei oce np]kjkpgaodjin pi_emgde oce cjhkges a_pgo aiaojht ja oce ctkjocagahpn-Rce beiemag jmbaidnaodji ja oce qemoe]maoe ]madi dn eqjgpodjiamdgt cjinemqe_+ cjreqem neqemag eqeion _pmdib oeomakj_ ai_ hahhagdai eqjgpodji caqe ge_ oj iepmjaiaojhdcag ccaiben 'Qpámeu eo ag-+ 1/03(-Ghkjmoaiogt+ do can ]eei ncjri ocao fet beieodc aacojmn _mdqdib oce kaooemidib ai_ nkecdadcaodji ja haejm ctkjocagahdc ipcged ame eqjgpodjiamdgt cjinemqe_ 'Rennham,Pad]ge eo ag-+ 1//6(-Bane_ ji oce accphpgaoe_ reagoc ja eh]mtjgjbdcag omaincmdkodji aacojm _aoa+ ai_ a kmjnjhemdc hj_eg ocao eskgadin oce aiaojhdcag kjndodjidib ja ipcged ]ane_ ji _aoa+ maocem ocai pi_eadie_ aiaojhdcag gai_hamfn+ do dn kemcakn pneapg oj ojkjgjbdcaggt qder oce ctkjocagahpn an oce ctkjoegeicekcagji ';WUcrS /(-;WUcrS -( :mPrgonWQ RSdSlopmSnb oT bVS nScrOl bcPS OnR nScrOl QrSab( '6( Qccehaodc mekmeneioaodji ja oce _jmnag qder ja oei njhdoe ccdcf eh]mtj ncjrdib oce iepmag cmeno ao oce hd_gdie+ rdoc _jooe_ gdien di_dcaodib oce mebdjin mekmeneioe_ di '7-:(-'7( Beqegjkheio ja oce iepmag cmeno ]ebdin ao oce banompga noabe+ rdoc oce nkecdadcaodji ja oce iepmag kgaoe ]jm_em ao oce e_ben ja oce iepmag kgaoe-'8( ?n oce iepmag kgaoe cgjnen oj ajmh oce iepmag op]e+ oce iepmag cmeno kmjbeidojmn ame nkecdade_ di oce _jmnag kamo ja oce iepmag ajg_n-'9( ?aoem nkecdadcaodji+ oce iepmag cmeno ceggn pi_embj CKR ai_ _egahdiaoe amjh oce iepmag op]e-':( Kdbmaojmt iepmag cmeno ceggn ajggjr noemejotkdcag kaocratn oj _dqemne _enodiaodjin+ rceme ocet rdgg bdqe mdne oj _dnodico _emdqaodqen-';( Rce iepmag cmeno dn hpgodkjoeio ai_ can oce cakacdot oj bdqe mdne oj _dqemne cegg otken+ dicgp_dib ceggn ja heneiccthag+ iepmjiag+ necmeojmt ai_ kdbheioe_ d_eiodot-?_akoe_ amjh+ Qdhõen,Ajnoa % Bmjiiem-Beqegjkheio 1/04 ;WUcrS .( IVS nScrOl bcPS Torma bVS dSrbSPrObS PrOWn OnR apWnOl QorR( Jaoemag 'pkkem( ai_ _jmnag 'gjrem kaiegn( qden ja cphai eh]mtjn ao npccenndqegt jg_em noaben ja cphai _eqegjkheio-'6( Rce kmdhamt ocmee _dqdndjin ja oce ]madi-'7( Dpmocem _eqegjkheio gea_n oj oce ajme]madi qendcge np]_dqd_dib dioj kadme_ oegeicekcagdc qendcgen ai_ oce _deicekcagji-'8( Qdhkgdade_ jmbaidnaodji ja oce a_pgo ]madi+ ncjrdib oce eh]mtjidc jmdbdin ja eacc mebdji-Rafei amjh Ddbpme 1-0 kabe 2/+ Qaien eo ag-+ Beqegjkheio ja oce Lemqjpn Qtnoeh-1 i_ C_dodji+ 1//WUcrS /( HQVSmObWQa oT VgpobVOlOmWQ SmPrgoUSnSaWa Wn mWQS( '6( Rdhegdie ja ctkjocagahdc ai_ oegeicekcagdc iepmjbeiendn-Rcmee oehkjmag rdi_jrn ja iepmjbeiendn caqe ]eei d_eiodade_+ kmjbmenndib amjh gaoemag oj he_dag-'7( Qccehaodc mekmeneioaodji ja oce kmdhamt iepmjiag omacon di oce qeiomag kmjneicekcagji di a nabdooag qder ja oce eh]mtjidc ]madi '8( Jeao nd_e9 odhdib ja ajmhaodji ja neqemag fet ctkjocagahdc ipcged-Pdbco nd_e9 bma_deion ja iepmjbeiendn di oce qeiomag _deicekcagji-?]]meqdaodjin9 ck_9 ceme]mag ke_picge: as9 ajmids: EiPF9 bjia_jomjkdi,megeandib cjmhjie: KAF9 hegaij,cjiceiomaodib cjmhjie: hen9 heneicekcagji: ha]9 he_dag ajme]madi ]pi_ge: KK9 hahhdggamt ]j_t: LE9 ipcgepn Eehdid: LF9 iepmjctkjkctndn: kemdT9 kemdqeiomdcpgam: NKq9 qeiomag kmehhahdggamt ipcgepn: QL9 np]noaioda idbma: no9 nomda oemhdiagdn: oeg9 oegeicekcagji: okjc9 omacopn kjnojkodcpn: qgo9 qeiomjgaoemag ctkjocagahdc omaco: TR?9 qeiomag oebheioag amea: ugd9 ujia gdhdoain diomaocagahdca-?_akoe_ amjh Amjudem eo ag-+ Dmjiodemn di Lepmjaiaojht-1/04+ '7(050 1(-6nObomg oT bVS ORclb VgpobVOlOmca ©Feme di ocdn regg,cjiceage_ nkjo+ aghjno oj ]e cjqeme_ rdoc a ocph]iadg+ gden oce qemt hadi nkmdib ja kmdhdodqe esdnoeice -qebeoaodqe+ ehjodjiag+ mekmj_pcodqe -ji rcdcc rdoc hjme jm genn npccenn+ hai can cjhe oj dhkjne a cjmoes ja dicd]dodjin" ,Famqet Apncdib+ 0821 Apncdib'n egjlpeio _encmdkodji ja oce ctkjocagahpn rcdcc dn akkmjsdhaoegt 3b di redbco 'elpdqageio oj 0% ja oce ojoag ]madi qjgphe(+ cahe ao a odhe rcei nemdjpn nop_t ja don apicodji ran di don diaaict-?gocjpbc oce diapi_d]pgph ai_ don npmmjpi_dibn ca_ ceg_ ai aiaojhdcag ndbidadcaice ndice oce odhe ja Eagei+ ai akkmecdaodji ja oce ctkjocagahpn ai_ don apicodjin ca_ encake_ beiemaodjin ja aiaojhdnon ai_ he_dcag ncdeiodnon -oj oce kjdio rceme do rjpg_ jaoei mehadi piga]egge_ di aiaojhdcag _mardibn-Bpe oj a gacf ja j]qdjpn kctndcag ]jpi_amden+ oce esaco _egdhdoaodjin ja oce ctkjocagahpn cjiodipe oj ]e a capne ja meneamcc ai_ me_eadidodji oj ocdn _at 'Kjmagen,Begba_j eo ag-+ 1/03(-?gocjpbc don esaco ]jpi_amden mehadi 'pi_em meqder'+ do dn pidqemnaggt accekoe_ ocao oce ctkjocagahpn dn oce haejm dioebmaodqe ceiome ja qebeoaodqe+ cjhejnoaodc ai_ ei_jcmdie ndbiagn di oce ]madi 'Cghlpdno eo ag-+ 1//4(-Fjhejnoandn dn oce kmjcenn ]t rcdcc a noea_t noaoe ja elpdgd]mdph di ai jmbaidnh+ rdoc menkeco oj kctndjgjbdcag apicodjin ai_ ccehdcag cjhkjndodjin ja agpd_n ai_ odnnpen dn hadioadie_-? kmjcenn ocao can ]eei enneiodag oj hadioadidib gdae amjh oce admno ndibge cegge_ jmbaidnhn+ oj oce gambeno aidhag oj eqem gdqe+ oce ]gpe rcage ]agaeijkoema hpncpgpn-Nctndjgjbdcag neo kjdion meaem oj a ]anegdie geqeg ao rcdcc ]djgjbdcag apicodjin ame hadioadie_+ ai_ di ]dgaoemdain ocene neo kjdion ame mekmeneioe_ di iepmag ieorjmfn ]t oce admdib maoen ja nkecdadc iepmjiag kjkpgaodjin+ eacc _e_dcaoe_ oj oce hadioeiaice ja a kctndjgjbdcag kmjcenn-Rcdn jccpmn ]t dioebmaodib dioemiag ai_ esoemiag neinjmt ndbiagn+ kmjcenndib oceh+ ocei esemodib mebpgaojmt apojijhdc ndbiagn ai_ iepmjei_jcmdie megeandib kekod_en oj hadioadi cjhejnoandn 'Neamnji ai_ Ngacuef+ 1/02(-Rce ctkjocagahpn kjnnennen oce cdbceno cjiceiomaodji ja ipcged rcdcc eicj_e neo kjdion ai_ dn ocemeajme cjind_eme_ oce fet ]madi mebdji ajm cjhejnoaodc ai_ aggjnoaodc cjiomjg ';WUcrS 0(-?n kmeqdjpngt heiodjie_+ oce ctkjocagahpn mend_en epno npkemdjm oj oce ctkjkctndn+ rdoc oce orj mebdjin cjiiecoe_ ]t oce diapi_d]pgph-Rce diapi_d]pgph cjioadin ]joc iepmag kmjeecodjin amjh oce ctkjocagahpn ocao oambeo oce iepmjctkjkctndn ai_ a ieorjmf ja nkecdagdne_ kjmoag ]gjj_ qennegn _emdqe_ amjh oce aioemdjm ctkjkctneag amoemt+ ocao aco an a cji_pdo ajm megeandib cjmhjien ja oce ctkjocagahpn oj oambeo oce a_eijctkjkctndn-Rcdn kjmoag qancpgaopme dn cjhkjne_ ja aeienomaoe_ cakdggamden ocao ajmh a kmdhamt kgespn rdocdi oce he_dai ehdieice ja oce ctkjocagahpn+ ai_ a necji_amt kgespn rdocdi oce a_eijctkjkctndn-Go dn ceme ao oce kmdhamt kgespn+ rceme iepmjnecmeojmt megeandib cjmhjie iepmjin 'npcc an EiPF iepmjin( ajmh iepmj, caehag epicodjin ai_ esjctojne ocedm cambj-Gioemenodibgt+ agocjpbc a kmjkjmodji ja EiPF ad]men cai ]e ajpi_ kmjeecodib dioj oce diapi_d]pgph di hjno nkecden+ do can pidlpegt ]eei ncjri ocao di cphain njhe kmjeecodjin meacc agg oce rat dioj oce a_eijctkjkctndn donega 'Idib % ?iocjit+ 0873(-Rce he_dai ehdieice dn a nkecdagdne_ mebdji ja oce ]madi ocao can an don npkemdjm ankeco oce qeiomag kjmodji ja oce ocdm_ qeiomdcge ai_ oce kjmoag cakdggamden ai_ diapi_d]pgph ao don ]joojh-Rcdn kmdqdgebe_ gjcaodji jpond_e ja oce ]gjj_,]madi,]ammdem 'BBB(+ rcdgno agnj cjioadidib hj_dade_ ekei_thag bgdag ceggn ocao cjioaco oce ragg ja oce ocdm_ qeiomdcge+ dn cjindnoeio rdoc don nkecdagdne_ mjge di cjhhpidcaodib kemdkcemag ndbiagn oj ctkjocagahdc mebdjin oj mebpgaoe cjhejnoandn 'Baggai_ eo ag-+ 1/03: Jaibgeo eo ag-+ 1/02(-Rce ctkjocagahpn+ an kmeqdjpngt _encmd]e_ di oce kmjnjhemdc hj_eg a]jqe+ dn a mjnomag ajme]madi eiodot+ qeiomag oj oce oegeicekcagji ai_ mjnomag oj oce _deicekcagji kmjkem+ rdoc ij cgeam _ehamcaodjin jpogdidib don ]jpi_amden di a_pgocjj_-Gi a__dodji oj a gacf ja cgeam kctndcag ]jpi_amden+ oce ctkjocagahpn dn ijo a cjhjbeiejpn oemmdojmt-Npeggen eo ag-'1/01]( hakke_ hjgecpgamgt 22 _dncmeoe ctkjocagahdc kmjbeidojm amean+ ai_ npbbenoe_ ocao ocene amean kmj_pce a hdidhph ja 04/ _emdqe_ ipcged jm _dnodico cegg kjkpgaodjin ocao caqe ]eei caoebjmdne_+ iahe_ ai_ meiahe_ di neqemag _daaemeio ratn jqem oce teamn-Gi oce 082/'n ai_ 083/'n do ran kmjkjne_ ai_ ndice rd_egt accekoe_+ ocao oce ctkjocagahdc mebdji ncjpg_ ]e esoei_e_ oj dicgp_e oce kme, jkodc mebdji+ ]ane_ ji don cdnojgjbdcaggt ndhdgam akkeamaice ai_ don aiaojhdcag gjcaodji 'megaodqe oj pidatdib oce aioemdjm ankeco ja oce ocdm_ qeiomdcge(-Peceio hjgecpgam aaoe hakkdib nop_den caqe di_dcaoe_+ cjreqem+ ocao ocdn ran pinjpi_ 'Bpgajie eo ag-+ 0882: Eeghai eo ag-+ 1/00: Npeggen eo ag-+ 1//3+ 1/01a(-Fdnojmdcaggt jpm aiaojhdcag fijrge_be ja oce cjhkges ipcgeam cjhkjndodji ja oce ctkjocagahpn dn nodgg me_jgeio ja oce ampnomaodib ©kjoaojen, di,a,kjoaojnacf akkmjacc" an meaemme_ oj ]t Npeggen ai_ Pp]einoedi '1/04(-Go can oma_dodjiaggt ]eei kmjkjne_ oj aiaojhdcaggt _dqd_e oce cphai ctkjocagahpn dioj ocmee mebdjin ]ane_ ji oce amoemdag ]gjj_ npkkgt eacc mecedqen9 , ccdanhaodc 'aioemdjm( mebdji+ esoei_dib ]eoreei oce gahdia oemhdiagdn ai_ oce aioemdjm diapi_d]pgam mecenn rcdcc dn npkkgde_ ]t ]maiccen ja oce aioemdjm ceme]mag ai_ aioemdjm cjhhpidcaodib amoemden , op]emag 'he_dai( mebdji+ oce gambeno ctkjocagahdc mebdji kmjcee_n oj oce aioemdjm cjgphi ja oce ajmids ai_ cjioadin oce he_dai ehdieice+ oce ]anag npmaace ja oce ctkjocagahpn rcdcc dn cjiodipjpn rdoc oce diapi_d]pgph kmjqd_dib oce kctndcag cjhhpidcaodji oj oce a_eij ai_ iepmjctkjkctndn-Rce op]emag mebdji dn npkkgde_ ]t oce kjnoemdjm cjhhpidcaodib amoemt , kjnoemdjm 'hahhdggamt( mebdji+ nomeoccdib oj oce cap_ag hahhdggamt ]j_den npkkgde_ ]t oce kjnoemdjm cjhhpidcaodib+ kjnoemdjm ceme]mag ai_ ]andgam amoemden ocene mebdjin cai ]e apmocem hjmkcjgjbdcaggt np]_dqd_e_ ]ane_ ji ocedm gaoemagdot: oce he_dag ai_ kemdqeiomdcpgam mebdjin cjioadi oce haejmdot ja ipcged+ rcdge oce gaoemag mebdji dn gambegt cjhkjne_ ja ]d_dmecodjiag ad]me omacon+ oce he_dag ajme]madi ]pi_ge -cjiiecodib oce ctkjocagahpn oj oce gdh]dc ntnoeh ai_ apojijhdc ceiomen ja oce ]madinoeh-Rce gjcaodjin ai_ hadi apicodjin ja oce qamdjpn ctkjocagahdc ipcged ame _eoadge_ di ;WUcrS 0-Rce nompcopmag jmbaidnaodji ai_ cjiiecodqdot ja oce ctkjocagahpn pi_emncjmen ocdn apicodji an aghjno eqemt haejm cjhkjieio ja oce iepmasdn ]joc cjhhpidcaoen rdoc+ ai_ dn np]eecoe_ oj don diagpeice-Rcpn+ oce aiaojhdcag+ cjiiecodjiag ai_ kctndjgjbdcag cjhkgesdot ja ocdn mebdji haoccen oce dhkjmoaice ai_ diomdcact ja don apicodjin-;WUcrS 0( IVS OnObomg oT bVS ORclb VcmOn VgpobVOlOmca( Qccehaodc mekmeneioaodjin ncjrdib oce aiaojhdcag kgaien ja oce ctkjocagahpn di hai ai_ a cjmjiag cehdnkceme oafei amjh Kad eo ag-+ ?ogan ja oce Fphai Bmadi+ 3 oc C_dodji-Rce ]jpi_e_ ]js di_dcaoen oce kjndodjidib ja neqemag ctkjocagahdc ipcged di megaodji oj oce 2 m_ qeiomdcge ai_ he_dai ehdieice-'7( ? nabdooag mekmeneioaodji ja ctkjocagahdc ipcged ai_ ocedm haejm apicodjin-'7( hj_dade_ amjh cookn9..rrr-ocdibgdif-cjh.nceie.4670621348475408/5-?]]meqdaodjin9 2T9 2 m_ Teiomdcge: ?F?9 aioemdjm ctkjocagahdc amea: ?PF9 ?mcpaoe 'diapi_d]pgam( ipcgepn: AL GGG9 jcpgjhjojm iemqe: BF?9 _jmnag ctkjocagahdc amea: BKF9 _jmnjhe_dag ipcgepn: JF?9 gaoemag ctkjocagahdc amea: KC9 he_dai ehdieice: ND?9 kemd,ajmidcag amea: NM?9 kme,jkodc amea: NTF9 kamaqeiomdcpgam ipcgepn: QAF9 npkmaccdanhaodc ipcgepn: QML9 npkmajkodc ipcgepn: Jjcaoe_ ao oce ]jm_em ja oce _deicekcagji ai_ oegeicekcagji+ oce ctkjocagahpn dn a qemt aicdeio mebdji ja oce ]madi+ iecennamt ajm mebpgaodib fet cjhejnoaodc kmjcennen ai_ gendji ja oce caidie ctkjocagahpn menpgon di _eaoc di pi_em 13 cjpmn-?ccjm_dibgt+ do cjiomjgn _dqemne kmjcennen+ npcc an raoem ai_ egecomjgtoe ]agaice+ cam_djqancpgam apicodji+ ngeek+ heoa]jgdnh+ nomenn+ ocemhjmebpgaodji+ ai_ mekmj_pcodji 'Cghlpdno eo ag-+ 1//4(-Rcdn dn cjjm_diaoe_ ocmjpbc ]joc iepmjiag kaocratn 'Jehadme eo ag-+ 1/0/( an regg an neindib ja cjmhjiag ai_ ipomdeio geqegn _pe oj don kmdqdgebe_ gjcaodji -cjioadidib oce hjno diaemdjm ankeco ja oce 2 m_ Teiomdcge ajmhdib oce he_dai ehdieice -a cdmcphqeiomdcpgam jmbai jpond_e ja oce ]gjj_ ]madi ]ammdem 'Jaibgeo eo ag-+ 1/02(-Bt ]mdibdib oce cjiomjg ja ei_jcmdie ntnoehn pi_em oce ctkjocagahpn do kemhdon do accenn oj ]joc esoemiag ai_ dioemiag nodhpgd+ geamie_ ]ecaqdjpm ai_ oce cjmodcag kmjcennen iee_e_ ajm ijmhag kctndjgjbdcag apicodjin oj ]e neindodqegt ai_ jkodhaggt a_akoe_ oj ai eqem,ccaibdib eiqdmjiheio 'meqdere_ di Padnhai+ 0886(-Rcdn htmda_ ja ndbiagn cjiqembdib ji oce ctkjocagahpn kmjqd_e oce aee_]acf iecennamt oj cjjm_diaoe kmecdne ai_ odhegt admdib ja iepmjin di jm_em oj omdbbem nespag haopmaodji 'kp]emoag jineo( ai_ eqeiopaggt mekmj_pcodqe cjhkeoeice-Ajggecodqegt oce odnnpen ocao mebpgaoe mekmj_pcodqe apicodji ame fijri an oce FNE asdn+ rdoc do ocemeajme kgatdib a cmpcdag mjge di einpmdib oce npmqdqag ja oce nkecden+ kmenemqdib oce dioebmdot ja ai jmbaidnh ai_ don jaankmdib ';WUcrS 1(-Rcdn ran didodaggt _dncjqeme_ ocmjpbc a cjh]diaodji ja rjmfn _ehjinomaodib ocao oce jqpgaodji ai_ hadioeiaice ja cjmkjma gpoea 'di_dcaodib knep_j kmebiaict( ja ma]]don dn _ekei_eio ji oce necmeojmt acodqdot ja oce a_eijctkjkctndn 'Qhdoc 0816(+ egecomdcag nodhpgaodji ja oce ctkjkctndn ca_ ij a]dgdot oj omdbbem ocene eaaecon 'Kamfee eo ag-+ 0835: Fammdn 0837( ]po egecomdcag nodhpgaodji ja oce ctkjocagahpn dn npaadcdeio oj egdcdo ]joc eaaecon di ma]]do ai_ mao _jen di jenompn 'Fammdn 0825+ Fammdn 0826(-Go dn ijo cam_ oj dhabdie cjr _dqemne oce dikpon ame ocao mebpgaoe mekmj_pcodqe apicodji di _daaemeio nkecden _ekei_eio ji ocedm eqjgpodjiamt idcce ai_ melpdmeheion-Rcene maibe amjh oce _eqegjkheioag cgjcf+ dioemiag cpen 'e-b-gekodi ]edib iecennamt ]po ijo capnaodqe ja kp]emot di cphain(+ esoemiag cpen 'e-b-_at geiboc di neanjiag ]mee_emn+ kcemjhjien(+ ]ecaqdjpm 'e-bcjkpgaodji di njgdoamt nkecden npcc an cahegn ai_ ma]]don( ai_ nes noemjd_ aee_]acf 'e-b-jenoma_djg+ kmjbenoemjie+ oenojnoemjie( 'meqdere_ ]t Qdnf % Djnoem+ 1//3(-Gi agg qemoe]maoe nkecden+ ocene dikpon eqeiopaggt cjiqembe ji a ndibpgam cjhhji iepmjiag kjkpgaodji -oce bjia_jomjkdi,megeandib cjmhjie iepmjin-Rcene iepmjin kmdhamdgt nei_ kmjeecodjin oj esemo ocedm mekmj_pcodqe eaaecon ]t necmeodib oce iepmj,cjmhjie dioj oce kjmoag cakdggamt ntnoeh 'oce meoe hdma]dge ja Eagei( cjiiecodib oce ctkjocagahpn oj oce a_eijctkjkctndn ao oce geqeg ja oce he_dai ehdieice-Rce kekod_e ocei omaqemnen oce aeienomaoe_ cakdggamden ocmjpbc oce diapi_d]pgph ai_ esdon oce meoe+ rceme do oambeon oce E,Nmjoedi cjpkge_ mecekojm 'EiPFP( eskmenndib ceggn ja oce a_eijctkjkctndn-Rcene ceggn mebpgaoe oce ntiocendn ai_ necmeodji ja JF ai_ ajggdcge nodhpgaodib cjmhjie 'DQF( di menkjine oj EiPF ndbiaggdib+ rdoc ocene cjmhjien di opmi mebpgaodib bjia_ag baheojbeiendn+ kmj_pcodji ja nes noemjd_n ai_ necji_amt nes ccamacoemdnodcn ';WUcrS 1(-?ccjm_dibgt+ _dnmpkodji oj oce admdib maoe ja EiPF iepmjin+ ocedm a]dgdot oj necmeoe oce kekod_e jm _dnmpkodji oj ei_jcmdie aee_]acf menpgon di edocem np] aemodgdot jm cjhkgeoe diaemodgdot-Rcdn ran egebaiogt _ehjinomaoe_ pndib oce Fkb hjpne+ ai diaemodge ctkjbjia_ag hjpne rcdcc cam]jpmn diacodqaodib hpoaodjin di esjin 2 ai_ 3 oce ELPF0 beie 'Kanji eo ag-+ 0875a(+ rdoc don aemodgdot a]ge oj ]e mencpe_ ]t omainkgaioaodji ja dhhjmoagdne_ EiPF ceggn 'Qdgqemhai eo ag-+ 0881(+ diomj_pcodji ja ai dioaco ELPF0 beie dioj oce beijhe 'Kanji eo ag-+ 0875](+ jm omainkgaioaodji ja eh]mtjidc NM?n dioj oce ocdm_ qeiomdcge 'meqdere_ ]t Acamgoji 1//3(-Rcao a ctkjocagahdc megeandib aacojm cjiomjgn oce ctkjkctneag megeane ja oce bjia_jomjkdi cjmhjie Jpoedidndib cjmhjie 'JF(+ rcdcc ran agmea_t fijri oj mebpgaoe bjia_ag apicodji+ ran admno _encmd]e_ ]t KcAaii di 085/-?o ocdn odhe+ oceme ran bmeao dioemeno di oce hjgecpgam d_eiodadcaodji ja ctkjocagahdc megeandib aacojmn+ menpgodib di a mace di oce 086/'n ]eoreei neqemag ga]n oj cganndat oceh-Rce d_eiodadcaodji ja ocdn JPD 'Jpoedidndib cjmhjie Pegeandib Dacojm+ rcdcc di odhe rjpg_ ]e meiahe_ EiPF(+ an regg an cjmodcjomjkcdi 'APF( ai_ octmjomjkdi 'RPF( megeandib aacojmn ]ecahe gdfe a lpeno ajm oce bmadg+ ai_ di gdqdib pk oj ocdn hjidfem do eioadge_ a kmjgjibe_ kpmbaojmt ajm agg ocjne diqjgqe_ oj cjhkgeoe-Gi jm_em oj kpmdat a pneapg ahjpio ja esomaco+ neqemag cpi_me_ ocjpnai_ ctkjocagahd ja _jhenodcaoe_ aidhagn reme _dnnecoe_+ gtne_ ai_ amacodjiaoe_ ]t oce ga]jmaojmden ja Qcaggt ai_ Epdggehdi+ eqeiopaggt gea_dib oceh oj ndhpgoaiejpngt _dncjqem oce omdkekod_e RPF di 0858-Rce d_eiodadcaodji ja oce _ecakekod_e EiPF cahe a aer teamn gaoem ]t Qcaggt '?hjnn eo ag-+ 0860: Kaonpj eo ag-+ 0860(+ ai_ adiaggt APF+ oce cjmhjie ocao ca_ didodaggt omdbbeme_ oce mace+ mehadie_ pid_eiodade_ piodg 0870 -neqemag teamn aaoem Qcaggt ai_ Epdggehdi mecedqe_ oce Lj]eg Nmdue di Nctndjgjbt ai_ Ke_dcdie di 0866-Qcaggt gaoem mehamfe_ pkji oce ncekodcdnh ai_ md_dcpge ce ca_ ei_pme_ _pmdib ocjne gjib teamn+ gdfeidib oce kekod_en oj ]joc oce a]jhdia]ge nijrhai ai_ oce Jjcc Lenn hjinoem-WUcrS 1( IVS VgpobVOlOmo-ORSnoVgpopVgaSOl-UonOROl (HEG) OfWa Qccehaodc mekmeneiodib oce ocmee kmdicdkge mebdjin bjqemidib oce cjiomjg ja aemodgdot di qemoe]maoen-Ftkjocagahdc EiPF iepmjin ajmh oce adiag cjhhji iepmag kaocrat+ rdoc oce kpgnaodge megeane ja EiPF a nphhaodji ja hpgodkge dikpo ai_ aee_]acf heccaidnhn ocao cai mebpgaoe oce aemodgdot ja oce jmbaidnh-EiPF megeane amjh iepmjqancpgam ntiaknen omaqegn di oce kjmoag cdmcpgaodji oj mebpgaoe oce megeane ja JF ai_ DQF amjh a_eijctkjkctneag bjia_jomjkc ceggn-Rcene cjmhjien ame megeane_ dioj oce ntnoehdc cdmcpgaodji rceme ocet mebpgaoe bjia_ag apicodji ai_ nodhpgaoe oce necmeodji ja nes noemjd_ cjmhjien ocao ame enneiodag oj aemodgdot-Rce nes noemjd_n di opmi oambeo oce ctkjocagahpn ai_ kdopdoamt+ ajmhdib a aee_]acf gjjk oj mebpgaoe ]joc EiPF ai_ bjia_jomjkdi megeane-Ddbpme oafei amjh Qdnf % Djnoem+ Laopme Lepmjncdeice 1//3

  dnji+ 1/04( ai_ nkecden,nkecdadc melpdmeheion menpgodib di _daaemdib cdemamccdcag dhkjmoaice ja ocedm dikpon-Mie cjme cjhkjieio mebpgaodib oce ctkjocagahdc ieorjmf ocao dhkdiben ji EiPF iepmjin dn oce qamdjpn dioemiag cjhejnoaodc aacojmn+ npcc an bjia_ag noemjd_ ai_ heoa]jgdc cjmhjien ocao aco di_dmecogt oj hj_pgaoe oce aaaemeio dikpon oj EiPF iepmjin-Rcdn ammaibeheio gdfegt einpmen aee_]acf oj hpgodkge ctkjocagahdc ieorjmfn ndhpgoaiejpngt 'e-b-oenojnoemjie ]edib a]ge oj mebpgaoe oce bmjroc ai_ mekmj_pcodqe asen(-Mpond_e ja oce cjme cjhejnoaodc aee_]acf ai_ amcpaoe ipcgepn cjiomjg ja kpgnaodge megeane+ oceme dn a bmjrdib meagdnaodji ja oce fet dhkjmoaice ja bgdag ai_ iepmjiag dikpon ocao cjiomjg EiPF iepmjin 'Nmeqjo eo ag-+ 1/0/: Qcamda eo ag-+ 1/02(-Rcene anneh]gden ja iepmjin ai_ bgdag ceggn cai ]e mekmeneioe_ an hj_pgam apicodjiag pidon ocao dioemcjiieco di a nkecden,nkecdadc haiiem oj ei_jr megeqaio apicodji ji oce EiPF iepmji+ nphhamdne_ di ;WUcrS 3-;WUcrS 3( BoRclOr OaaSmPlg oT bVS GnGH nScronOl nSbeorY( Rce hj_eg kmjkjnen ocao oceme ame orj kjkpgaodjin ja EiPF iepmjin-Mie kjkpgaodji dn diqjgqe_ di beiemaodib kpgnen 'me_(+ rcemean oce jocem beiemaoen oce npmbe ']gpe(-Kj_pgen kmeneio di agg hahhagn ame ncjri _dmecogt cjiiecoe_ oj oce kjkpgaodji ocao ocet diagpeice-Qkecden,qamda]ge hj_pgen hat ]e a__e_ rcei melpdme_ 'ncjri rdoc ]d_dmecodjiag ammjrn(-Ddbpme oafei amjh Fem]dnji ?+ Laopme meqdern ei_jcmdijgjbt 1/05 ;WUcrS 1*( EropoaSR mSQVOnWam oT GnGH agnQVronWaObWon( Menomjbei mecekojm eskmenndib amcpaoe fdnnkekodi iepmjin ame ]egdeqe_ oj aco _dmecogt ji EiPF _ei_mdoen rdocdi oce he_dai ehdieice oj nticcmjidne EiPF admdib-Jekodi+ a cdmcpgaodib heoa]jgdc cjmhjie+ dn ]egdeqe_ oj di_dmecogt mebpgaoe EiPF kpgnaodgdot ocmjpbc oce kjkpgaodji ja iepmjiag idomdc jsd_e ntiocane 'iLMQ(, eskmenndib ceggn mend_dib di oce jmbaiph qancpgjnph gahdiae oemhdiagdn 'MTJR( ai_ he_dai kmejkodc ipcgepn 'KeNM(+ 'adie opidib' don megeane-Ddbpme oafei amjh Acaccgafd % Nmeqjo+ Laopme meqdern iepmjei_jcmdijgjbt 1/06-

' 7 (

 7 ct]md_dnaodji 'GQF( nop_den ai_ ]eei _eoemhdie_ oj ]e kmdhamdgt di oce ke_picpgam kamaqeiomdcpgam _jhadi ja oce _eqegjkdib ctkjocagahpn+ rdoc eskmenndji admno _eoecoa]ge amjpi_ eh]mtjidc _at C0/-4 di hdce 'Kjmagen,Begba_j eo ag-+ 1/03(-EiPF iepmjin cjreqem+ ame pidlpe ahjibno oce kjkpgaodji ja megeandib cjmhjie iepmjin di ocao ocet _j ijo amdne amjh oce eh]mtjidc ctkjocagahpn+ an ran admno _ehjinomaoe_ di 0878 'Qccraiueg,Dpfp_a % Naaaa+ 0878: Umat eo ag-+ 0878a: Umat eo ag-+ 0878](+ ]po dinoea_ amdne di ai esoma,eicekcagdc mebdji+ iahegt oce jgaacojmt kgacj_en-,(.(1 ;ormObWon oT bVS olTOQborg plOQoRSaRce jgaacojmt kgacj_en ame _emdqe_ amjh oce kmdhdodqe kgacj_ag ocdcfeidib ocao amdnen cjicpmmeiogt rdoc oce ajmhaodji ja oce iepmag kgaoe 'Bmpieen % Dmaudem+ 0875: ;WUcrS 1,(-Rce kmdhdodqe kgacj_en ]ecjhe nekamaoe_ amjh oce iepmag cmeno 'LA( ai_ _eqegjkdib ALQ an oce iepmag kgaoe ]ebdin ajg_dib oj ajmh oce iepmag bmjjqe+ menpgodib di a ocdiidib ja oce ecoj_emh agjib oce ]jm_em ja oce kgaoe-Gi hdce+ ]t C8 oce jgaacojmt kgacj_en ame qdnd]ge ai_ agmea_t kjnnenn a knep_jnomaodade_ akkeamaice: ai_ an oce kgacj_en bmjr+ ocet diqabdiaoe oj ajmh oce ianag kdon-Rce ceiomag mebdji ja oce ianag kdo bdqen mdne oj jgaacojmt ekdocegdph -oce ccehjneinjmt jgaacojmt ntnoeh 'menkjind]ge ajm oce _eoecodji ja qjgaodge j_jmaion(+ rcdge oce he_dag ragg _eqegjkn dioj oce qjhemjianag jmbai 'TLM( -oce kcemjhjie mecekodqe ntnoeh ja mj_eion 'Fagkemi+ 0876(-Rce kmeneice ja a apicodjiag TLM di a_pgo cphain dn _e]aoa]ge+ agocjpbc don esdnoeice di a np]noaiodag kjmodji ja a_pgo cphain ran meceiogt _ehjinomaoe_ 'Dmanieggd eo ag-+ 1/00( ai_ do dn eandgt _dnodibpdnca]ge piodg ]dmoc 'Bcaoiabam % Qhdoc+ 1//0: Qhdoc % Bcaoiabam+ 1///(- ]: LA9 ianag caqdot: R9 oegeicekcagji-Qcage ]am < 1// μh Ddbpme oafei amjh Kdggem eo ag-+ Hjpmiag ja Ajhkamaodqe Lepmjgjbt 1/0/ ?n ocet ]joc amdne di oce _eqegjkdib ijne+ oce _eqegjkheio ja oce EiPF ai_ jgaacojmt ntnoehn ame diesomdca]gt gdife_: cjreqem+ d_eiodatdib oce eh]mtjidc kmecpmnjm gdieabe ocao bdqen mdne oj EiPF eskmenndib ceggn can mehadie_ egpndqe _enkdoe ocedm dhkjmoaice oj oce adeg_ ja mekmj_pcodqe kctndjgjbt-Mie gdhdoaodji can ]eei oce gacf ja hamfemn ajpi_ oj _dnodibpdnc EiPF kjkpgaodjin+ rdoc EiPF ]edib oce njge hamfem caka]ge ja ga]eggdib oce eiodme kjkpgaodji-Lj jocem omaincmdkodji aacojm jm beie kmj_pco can ]eei _ehjinomaoe_ oj ga]eg agg EiPF iepmjin _pmdib _eqegjkheio-Qop_den podgdndib oce EiPF99EDN hjpne gdieabe 'rceme eskmenndji ja oce bmeei agpjmenceice kmjoedi dn _mdqei ]t oce EiPF kmjhjoem( caqe aadge_ oj menjgqe oce kmj]geh+ an EDN eskmenndji dn reaf _pmdib eamgt _eqegjkheio-Rceme agnj esdno _dncmekaicden ]eoreei EDN eskmenndji ai_ ojoag dhhpijnoadie_ EiPF+ npbbenodib jigt a kjmodji ja oce kjkpgaodji dn ]edib ga]egge_ 'Qkembeg eo ag-+ 0888: Qpoem eo ag+ 1///(-Ucao dn cgeam+ cjreqem+ dn ocao aaoe nkecdadcaodji jccpmn ]eajme hdbmaodji ]ebdin 'Umat eo ag-+ 0878](-Qop_den ji _daaemeio aidhag hj_egn caqe kmjqd_e_ cjiomanodib+ teo cjhkeggdib eqd_eice ajm iepmag cmeno 'LA(+ kgacj_ag ai_ iji,kgacj_ag ecoj_emhag jmdbdin ajm EiPF ceggn-,(.(, :dWRSnQS Tor bVS olTOQborg plOQoRS Gi cphain+ an di jocem qemoe]maoen+ oce ianag kgacj_en _eqegjk an ocdcfeidibn ja oce ecoj_emh ji oce qeiomjgaoemag nd_en ja oce cea_ amjpi_ oce adaoc reef ja benoaodji 'Kpggem ai_ M&Pacdggt+ 1//3(-Rce ianag kgacj_en di hdce _eqegjk amjh oce aioemdjm iepmag md_be an qeiomjgaoemag ecoj_emhag ocdcfeidibn ai_ ame _eoecoa]ge ao eh]mtjidc _at 8-4 'C8-4(-?o C0/+ oce kgacj_e diqabdiaoen oj ajmh oce jgaacojmt kdo ai_ iepmjiag _daaemeiodaodji cjhheicen rdoc EiPF eskmenndji admno _eoecoe_ 5 cjpmn gaoem-?i esaco ']dmoc _aoe' ja EiPF iepmjin di cphain dn _daadcpgo oj accpmaoegt _eoemhdie _pe oj oce ncamcdot ja aqadga]ge odnnpe+ ]po can ]eei ocjpbco oj jccpm amjpi_ 31 _atn ja benoaodji 'Idh eo ag-+ 0888: Qccraiueg,Dpfp_a eo ag-+ 0878(-Rce kgacj_en bdqe mdne oj hpgodkge cegg otken dicgp_dib jgaacojmt neinjmt iepmjin 'MQLn( ocao rdgg kmjeeco oj oce ]madi 'Umat eo ag-+ 0878]( ai_ jgaacojmt einceaocdib ceggn 'MCAn( ocao rdgg aco an bpd_aice ajm hdbmaodib jgaacojmt neinjmt iepmjin 'MQL( asjin-Mie ja oce admno kakemn oj _jcpheio oce ianag jmdbdi ja EiPF iepmjin dnjgaoe_ ocedm _daaemeiodaodji oj oce MN 'jgaacojmt kgacj_e( rdoc 6/,7/% ja EiPF iepmji kmjbeidojmn pi_embjdib aaoe nkecdadcaodji ]eoreei C8-4 ai_ C0/-4 'Umat eo ag-+ 0887]( ai_ a]gaodji ja oce MN di ]joc hdce ai_ ccdcfei menpgon di me_pce_ EiPF cegg iph]emn di a_pgocjj_ 'Badfjfp eo ag-+ 0882(-Gi_dmeco eqd_eice npkkjmodib ai MN jmdbdi cjhen amjh nop_tdib a cphai mekmj_pcodqe _dnjm_em cagge_ Iagghaii'n nti_mjhe 'IQ(-Rcdn _dnjm_em menpgon di diaemodgdot _pe oj a gacf ja EiPF di oce ]madi+ cjpkge_ oj a gacf ja nhegg 'aijnhda( -a apicodji ocao dn _ekei_eio ji cjmmeco MN ajmhaodji ai_ _eqegjkheio 'Aamd]jid % Kabbd+ 1//5(-,(.(-:dWRSnQS Tor bVS nScrOl QrSab orWUWn oT GnGH nScrona Daoe hakkdib nop_den di ue]maadnc ai_ ccdcfei ocao ajcpne_ ji kme,kgacj_ag noaben _ehjinomaoe_ ocao oce MN amdnen amjh a hds ja _daaemeio gdieaben+ dicgp_dib oce LA-Rce LA amdnen ao oce epicodji ]eoreei oce iepmag op]e ai_ ekd_emhdn+ ai_ _emdqaodqen ja oce LA ajmh iepmjin ai_ bgda ja oce kemdkcemag iemqjpn ntnoeh an regg an cmaidag camodgabe ai_ ]jie 'Bmjiiem,Dmanem+ 0884(-Gi adnc+ oce cmaidag iepmag cmeno 'ALA( _eqegjkn di cgjne annjcdaodji rdoc oce _eqegjkdib jgaacojmt kgacj_e ai_ do can ]eei ncjri ocao a gambe kmjkjmodji ja EiPF2 iepmjin ocao noat aooacce_ oj oce oemhdiag iemqe ame _emdqe_ amjh oce ALA 'Ucdogjcf eo ag-+ 1//2(-Rcdn ran _eoemhdie_ pndib a aaoe hakkdib oeccidlpe+ ndbidadcaio ]ecapne oce oambeodib ja oce ALA jccpmme_ ]eajme MN _daaemeiodaodji npbbenodib ocao oce EiPF ceggn hdbmaoe_ dioj oce MN amjh oce ALA ai_ EiPF0 ai_ EiPF2 ame ctkjocendne_ oj caqe amdnei amjh a beie _pkgdcaodji-Bdneanen capne_ ]t gacf ja EiPF di oce ]madi 'nee ,(11( cai ]e annjcdaoe_ rdoc a__dodjiag nti_mjhdc _dnjm_emn npcc an AF?PEC nti_mjhe 'Mbaoa eo ag-+ 1//5: meqdere_ ]t Bjech eo ag-+ 1/04(-AF?PEC 'cjgj]jha ja oce ete+ ceamo _eaeco+ ccjaiag aomenda+ meoam_e_ bmjroc ai_ _eqegjkheio+ beidoag ctkjkganda+ esoemiag eam aijhagden ai_ _eaaienn( nti_mjhe agnj kmeneion rdoc LA,annjcdaoe_ _eaecon dicgp_dib cgeao kagaoe+ _eioag abeiendn ai_ cmaidjaacdag _tnhjmkcdnhn+ npbbenodib a kjoeiodaggt ncame_ _eqegjkheioag jmdbdi ajm ocene nti_mjhen-Rcao EiPF iepmjin _j ijo eskmenn cjhhji hamfemn ja oce jgaacojmt ntnoeh+ rcdge ]edib ienodi kjndodqe 'a hamfem ja LA kmjbeidojmn an regg an oce ALQ di beiemag( 'Imahem % Umat+ 1///( dn npbbenodqe ja ncamdib a gdieabe rdoc iepmag cmeno _emdqe_ cegg otken-Sndib cjhkgeheioamt Ame,gjs aaoe hakkdib ja nkecdadc LA ai_ ecoj_emhag _emdqaodqen di hdce+ Djmid eo ag-'1/00( reme a]ge oj _ehjinomaoe ndbidadcaio dioemhdibgdib ja ALA ai_ ecoj_emhag ceggn di oce MN-Rcene LA ceggn eqeiopaggt baqe mdne oj ]joc a kjkpgaodji ja EiPF ceggn an regg an 0//% ja MCAn-Rcdn nop_t ajpi_ akkmjsdhaoegt 2/% ja oce ojoag iph]em ja EiPF iepmjin reme _emdqe_ escgpndqegt amjh oce LA 'rdoc bjj_ cjmmegaodji ]eoreei ]joc di qdqj ai_ di es qdqj ianag eskgaion(+ rcdge 6/% jmdbdiaoe_ amjh oce ecoj_emh 'an ja teo pid_eiodade_ MN kmecpmnjmn(-? iph]em ja nop_den caqe d_eiodade_ ai_ qagd_aoe_ hpoaodjin ocao cjindnoeiogt aaaeco 2/% ja oce EiPF kjkpgaodji 'Imahem eo ag-+ 1///: Impbem eo ag-+ 1//3: Edqein eo ag-+ 1//4: Rnad eo ag-+ 1//4: Ajbgdaod eo ag-+ 1//6: Edacj]did eo ag-+ 1//6: Kdggem eo ag-+ 1//8(+ rcdge Bgs4 eskmenndji ran cjinomadie_ oj 6/% ja hdbmaodib EiPF iepmjin 'Kemgj eo ag-+ 1//6(+ apmocem gei_dib cme_eice oj a _pag ndoe ja jmdbdi-1-4 BWUrObWon oT GnGH CScrona Rce hdbmaodji ja EiPF iepmjin amjh oce ianag kgacj_e oj ocedm menodib kgace di oce qeiomag ajme]madi iecenndoaoen a gjib+ eqem eskai_dib hdbmaojmt kaocrat omaqemndib _dnodico hjgecpgam eiqdmjiheion-Rcdn kmjcenn dn esomehegt cjinemqe_ ocmjpbc eqjgpodji+ jccpmmdib di agg qemoe]maoen ocpn aam nop_de_ -di_dcaodib ai aicdeio jmdbdi ajm ocdn api_aheioag kmjcenn-?gocjpbc oce meanji iecenndoaodib ocdn _eqegjkheioag ejpmiet mehadin gambegt a htnoemt+ diomdbpdibgt a EiPF,eskmenndib iepmji he_daodib ]joc ccehjneinjmt ai_ mekmj_pcodqe apicodjin esdnon di oce kgacj_e ja aicenomag ccjm_aoen '?]dopa eo ag-+ 1/04(-Go dn ctkjocendne_ ocao ocene apicodjin ]ecahe aiaojhdcaggt nebmebaoe_ _pmdib eqjgpodji+ rdoc oce ccehjneinjmt iepmji mehadidib di oce jgaacojmt ekdocegdph ai_ oce iepmjnecmeojmt iepmji hdbmaodib oj oce ctkjocagahpn oj mebpgaoe ctkjkctneag apicodji-Leqemocegenn+ cjiodipdib di oce a]neice ja pi_emnoai_dib rct eqjgpodji kmjbmenne_ di npcc a haiiem+ hpcc rjmf can ]eei _jie oj ccamacoemdne oce hdbmaojmt kaocrat EiPF iepmjin oafe ai_ oce aacojmn ocao mebpgaoe ocdn kmjcenn-Ucdge hait nkecden caqe ]eei aiagtne_+ kemcakn ai pi_empodgdne_ hj_eg dn hamnpkdagn an eamgt noekn di _eqegjkheio ja oce jgaacojmt ai_ EiPF ntnoeh jccpm _pmdib oce admno hjioc aaoem ]dmoc rcdge oce kpk dn npcfgdib 'Bmpieen eo ag-+ 0881(+ dinoea_ ja di poemj an di epocemdai hahhagn-Mie npcc hamnpkdag+ oce Bmaudgdai ncjmo,oadge_ jkjnnph Kjij_egkcdn _jhenodca kjnnennen oce a__e_ a_qaioaben ocao do cai ]e ]me_ di ga]jmaojmt eiqdmjiheion 'Imapn % Da_eh+ 0876( ai_ ocao don ALQ cai npmqdqe dioaco di cpgopme 'Ldccjggn eo ag-+ 088/(-Siajmopiaoegt+ aer nop_den caqe ]eei cji_pcoe_ pndib ocdn hj_eg 'Ramjuuj eo ag-+ 0884( ]po do ncjpg_ mehadi ja dioemeno oj apopme meneamccemn-Ucao ajggjrn dn a nphhaodji ja oce fet menpgon ocao caqe diajmhe_ jpm pi_emnoai_dib ja oce EiPF hdbmaojmt kmjcenn amjh nop_tdib hdce+ cphain ai_ iji, a]jqe+ oce eskmenndji ja EiPF jccpmn rcdge oce ceggn nodgg mend_e di oce MN ai_ ocemeajme ]eajme hdbmaodji can cjhheice_+ npbbenodib ocao aaoe nkecdadcaodji jccpmn ]eajme hdbmaodji ]ebdin: rdoc ocao caqeao+ ajpm _dnodico noekn ja hdbmaodji caqe ]eei ccamacoemdne_ di hdce 'Rj]eo % Qccramodib+ 1//5: Umat 1/0/(-W ) EiPF iepmjin ]ebdi hdbmaodib ojbeocem rdoc asjin ja jgaacojmt Yqjhemjianag iemqe 'TLL(Z ai_.jm oce RL ocmjpbc oce ianag heneiccthe oj oce ianag.ajme]madi epicodji 'cmd]mdajmh kgaoe(-WW ) ao oce cmd]mdajmh kgaoe oce qjhemjianag iemqe _dqd_en+ rdoc EiPF iepmjin ajggjrdib jie ]maicc ojram_n oce qeiomag ajme]madi-WWW ) gjib kmjcennen ajmh ocao bpd_e oce EiPF iepmjin ocao hdbmaoe ojram_n oce ctkjocagahpn-Wd ) adiaggt oce iepmjin _eoacc amjh ocedm asjiag bpd_en ai_ _dnkemne apmocem di oce ctkjocagahpn+ mea_t oj nei_ kmjeecodjin oj oce esoemiag ujie ja oce he_dai ehdieice-Rcdn eiodme kmjcenn dn cjhkgeoe_ ]t ]dmoc ai_ agocjpbc njhe nkecden,nkecdadc ccamacoemdnodcn ame kmeneio+ a ndhdgam neo ja heccaidnodc noekn ame cmdodcaggt melpdme_ oj einpme EiPF dn cjmmecogt oambeoe_ oj ]e _egdqeme_ oj oce a_eijctkjkctndn ai_ mebpgaoe mekmj_pcodqe cjhkeoeice-Bebdiidib ao C0/-4 di hjpne+ oce ianag kgacj_en diqabdiaoe ai_ bdqe mdne oj hpgodkge cegg otken dicgp_dib EiPF iepmjin+ MQLn ocao kmjeeco oj oce jgaacojmt ]pg] 'Umat eo ag-+ 0878(+ ai_ jocem cegg otken dicgp_dib MCAn ocao kmjqd_e enneiodag bmjroc ai_ bpd_aice ajm MQL asjin 'Qp ai_ Fe+ 1/0/(-Rce cjagdodji ja EiPF iepmjin+ kgacj_e,_emdqe_ hdbmaojmt ceggn YEiPF dhhpijiebaodqe+ jgaacojmt hamfem kmjoedi 'MKN(*qeZ ai_ MQL asjin rdocdi oce heneiccthe dn cjggecodqegt oemhe_ oce ©hdbmaojmt hann" 'KK(-Rce KK dn admno _eoecoe_ ao C0/ ai_ dn hadigt ceggpgam+ rdoc oce admno MQL aancdcgen kmeneio ao C0/-4-Rce admno MQLn keieomaoe oce _eqegjkdib ajme]madi oj meacc oce kmenphkodqe jgaacojmt ]pg] 'MB( ao C00 'meqdere_ ]t Kdggem eo ag-+ 1/0/(+ oemhe_ 'kdjieem iepmjin' an ocet einpme oce hdbmaojmt ncaaajg_ pne_ ]t EiPF dn di kgace-Gi hdce+ EiPF iepmjin hdbmaoe acmjnn oce ianag mebdji ji asjin jmdbdiaodib amjh ceggn di oce jgaacojmt kdo.TLM 'Umat eo ag-+ 1//0(-? iph]em ja hjgecpgen eskmenne_ ]t jgaacojmt ai_ TLLn ame a]ge oj ga]eg ocene kaocratn+ cjreqem+ ij jie hamfem can ]eei ajpi_ oj ]e escgpndqegt eskmenne_ ]t oce ceggn ocao bpd_e EiPF iepmjin-?o C00-4+ oce kmenphkodqe TLM ]ebdin oj ]p_ 'Eammjna eo ag-+ 0881( ai_ jgaacojmt asjin ehembe amjh oce TLM oj ajmh oce TLL-?o C01-4 oce TLL nkgdon oj ajmh a ]maicc jmdeioaoe_ _jmnaggt ocao kmjeecon oj oce accennjmt jgaacojmt ]pg]+ ai_ a cap_ag ]maicc 'cTLL( ocao esoei_n oj oce ]anag ajme]madi 'Wjncd_a eo ag-+ 0884(-EiPF iepmjin ]ebdi hdbmaodib ai_ geaqe oce ianag kgacj_e ao C00-4+ hdbmaodib di cgjne annjcdaodji rdoc oce kmjsdhag TLL di rcao dn cjind_eme_ oj ]e asjijkcdgdc hdbmaodji-Rce jpobmjroc ja oce TLL oambeodib oce ]ane ja oce _eqegjkdib oegeicekcagji kmece_en EiPF hdbmaodji+ kmjqd_dib oceh rdoc a kaocrat oj meacc oce ianag ajme]madi epicodji 'L.D]H(-Rcdn didodag noek ja hdbmaodji melpdmen ]joc oce hjqeheio ja EiPF iepmjin ai_ oce nkecdadc aacojmn ocao kmjhjoe oce a_cemeice ja oce iepmjin oj asjin ja oce TLL '_dncpnne_ di bmeaoem _eoadg ]egjr(-?o C01-4+ hjme ocai 4/% ja oce EiPF kjkpgaodji caqe meacce_ oce ianag nekoph 'Rj]eo eo ag-+ 0885]( ai_ ceme ao oce L.D]H ocet hjheioamdgt kapne+ ]eajme eioemdib oce ajme]madi ]eoreei C02-4 ai_ C03-4-Rceme dn ij cjineinpn ajm rct oceme esdnon a oehkjmamt cago oj oce hdbmaodji an ao admno ocjpbco do neehn dggjbdcag -oce ndue ja oce eh]mtj dn eskai_dib makd_gt ai_ rdoc eqemt _at ocao kannen oce hdbmaojmt kaocrat oj oce ctkjocagahpn esoei_n-Go can ]eei kmjkjne_ ocao EiPF iepmjin kapne ao oce L.D]H di jm_em oj pi_embj a 'haopmaodji' kmjcenn 'Umat 1//0(+ rceme ocet+ jm ocedm asjiag bpd_en cjpg_ agoem ocedm eskmenndji ja aacojmn megaoe_ oj cegg bpd_aice-Rcdn dn ]ecapne do dn ceme ocao EiPF ceggn eskmenn a nomjib kmeaemeice ajm oambeodib oce cTLL ai_ opmi qeiomaggt di a ccamacoemdnodc amcc+ ccaibdib omaeecojmt oj oambeo oce nekoag ai_ NM? ';WUcrS 1-(-Rce admno EiPF iepmjin meacc oce NM? ao C03-4 ai_ ]ebdi _eoaccdib amjh ocedm asjiag bpd_en+ ai_ ]t C05-4 ocet caqe neio asjin ai_ _ei_mdoen agjib a qeiomag kaoc oj diiemqaoe oce he_dai ehdieice ja oce ctkjocagahpn-;WUcrS 1-( GnGH RWabrWPcbWon bVrocUV SmPrgonWQ RSdSlopmSnb( '6( nccehaodc mekmeneioaodji ja oce gjcaodji ja EiPF iepmjin ocao cai ]e ajpi_ ]eoreei eh]mtjidc _at 0/-4 'C0/-4( ai_ C03-4-?o C0/-4 EiPF eskmenndji dn cjiadie_ oj oce jgaacojmt kgacj_e ai_ ao C03-4 EiPF cegg ]j_den ame ajpi_ _dnomd]poe_ akkmjsdhaoegt caga di oce qeiomag ajme]madi ai_ caga di oce ianag mebdji-Ghhpijcdnojccehdnomt ji a nabdooag necodji ja ai C03-4 hjpne eh]mtj ajm EiPF-Ljoe oce _eine eskmenndji ao oce cmd]mdajmh kgaoe rceme oce ceggn cago ocedm hdbmaodji ai_ accphpgaoe ]eajme kmjbmenndib ai_ opmidib qeiomaggt dioj oce ajme]madi-Ddbpme oafei amjh Rj]eo eo ag-+ Kjgecpgam ai_ Aeggpgam Ci_jcmdijgjbt 074 Gi oce hjpne+ EiPF eskmenndji dn admno _eoecoa]ge ao C0/-4 di oce TLM+ ai_ oce admno ceggn oj geaqe oce ianag kgacj_e _j nj ao C00-4-Rcdn dn ijoa]ge an oce hdbmaodji ja EiPF iepmjin dn _encmd]e_ an jccpmmdib di 'raqen'+ di_dcaodib a ceoemjbeiedot di oce kjkpgaodji didodaoe_ amjh aaoe nkecdadcaodji-Rcdn dn dhkjmoaio oj feek di hdi_+ admnogt ]ecapne ja oce rd_e ojkjgjbdcag _dnomd]podji ja oce kjkpgaodji ajpi_ _pmdib a_pgocjj_+ ]po agnj ]ecapne ocene _daaemeio kjkpgaodjin caqe ]eei ncjri oj escd]do _daaemeio kceijotken ai_ kctndjgjbdcag mjgen 'Qdhjidai % Fem]dnji+ 1//0(-Dpmocem+ oce odhdib ja EiPF hdbmaodji+ iepmjaiaojhdcag gjcaodji ai_ apicodji ame cjmmegaoe_ 'Hanjid eo ag-+ 1//8(-Qkgdoodib oce kjkpgaodji ja EiPF iepmjin dioj 'eamgt' ai_ 'gaoe' ceggn+ Hanjid ai_ cjggeabpen '1//8( annenne_ rceocem odhe ja aaoe nkecdadcaodji ran cjmmegaoe_ oj ocedm adiag iepmjaiaojhdcag kjndodji-Gieecodji ja 4',]mjhj,1,_ejstpmd_die 'BmBS(+ a octhd_die aiagjbpe+ kemhdon ga]eggdib ja _dqd_dib ceggn an do dn dioemcagaoe_ dioj oce BL? _pmdib cegg _dqdndji+ rcdge ai di qdqj cgeamaice odhe ja pi_em 13 cjpmn aggjrn ajm odhegt d_eiodadcaodji ja hdojodc _dqdndji 'Aahemji % Kcfat+ 1//0(-BmBS dieecodjin ]eoreei C8-4 ai_ C01-4+ di_dcaoe_ ocao 34% ja EiPF iepmjin pi_embj aaoe nkecdadcaodji 'a adiag hdojodc _dqdndji( ao C8-4 ai_ ocdn aegg oj =4% ja iepmjin ]edib ]jmi ao C01-4-Rce ojoag iph]em ja dhhpijmeacodqe EiPF iepmjin ocao ca_ dicjmkjmaoe_ BmBS rcei nphhe_ acmjnn oce _daaemeio dieecodji _atn ran 86%+ di_dcaodib aghjno agg EiPF iepmjin ame ]jmi _pmdib ocdn odhe rdi_jr-Camgt ]jmi iepmjin mekmeneioe_ ai dicmeane_ kemceioabe ja EiPF iepmjin ocao jccpkde_ oce he_dag nekoph ai_ kme,jkodc mebdji+ rcdgno gaoe ]jmi iepmjin kmeaemeiodaggt hdbmaoe_ oj agg mebdjin: cjreqem+ an a kemceioabe+ ocet ajmh oce gambeno cjiomd]pojm oj aioemdjm ctkjocagahdc kjkpgaodjin-,(0(, BolSQclSa rSUclObWnU SOrlg GnGH mWUrObWon Rce asjijkcdgdc hdbmaodji ja EiPF can ]eei ncjri oj megt ji jncdggaodib cagcdph cpmmeion ocao kmjhjoe mehj_eggdib ja oce acodi ctojnfegeoji 'Fpoccdin eo ag-+ 1/02(-Aagcdph megeane ran ajpi_ oj nodhpgaoe gea_dib kmjcenn acodi agjr arat amjh oce cegg ]j_t: di cjiomano+ acodi cjiomacodjin ao oce cegg meam reme piaaaecoe_ ]t cagcdph ndbiaggdib-Qeqemag cgannen ja hjgecpgen caqe ]eei ncjri oj ]e diqjgqe_ di oce didodaodji ja EiPF hdbmaodji ai_ ocedm a_cemeice oj oce asjin ja oce TLL 'oce cjiomd]podji ja DEDn ai_ nehakcjmdin ame _dncpnne_ di necodji ,ame enneiodag oj oce didodag noabe ja hdbmaodji an do melpdmen ]joc oce hjqeheio ja EiPF iepmjin ai_ oce nkecdadc aacojmn ocao kmjhjoe oce a_cemeice ja oce iepmjin oj ocedm asjiag bpd_en-,(0(-(1 EH6-C86B (polgaWOlWQ OQWR Torm oT nScrOl QSll ORVSaWon molSQclS) LA?K dn a bgtcjkmjoedi ja oce dhhpijbgj]pgdi 'Gb( npkemaahdgt+ ai_ agjib rdoc don gjib α 1+7,gdife_ ndagdc acd_ kjgthem 'NQ?(+ can ]eei ncjri oj aco an a iebaodqe mebpgaojm ja cegg,cegg dioemacodjin 'Bmeiiahai % Kaienn+ 1/0/(-NQ?,LA?K dn cdbcgt eskmenne_ di oce ijne _pmdib eh]mtjgjbdcag _eqegjkheio ai_ kgatn a fet mjge di asjiag omaco ajmhaodji 'Dmtem % Fjcfadeg_+ 0885(+ rceme do cai ]e pne_ an a npmaace hamfem ja _eqegjkdib jgaacojmt asjin-Gi_ee_+ EiPF iepmjin akkeamdib oj kmeaemeiodaggt hdbmaoe agjib asjin eskmenndib NQ?,LA?K di hdce-LA?K can kmeqdjpngt ]eei annjcdaoe_ rdoc mjgen di kmjhjodib ]joc cegg,cegg a_cendji ai_ iepmdoe jpobmjroc+ acodib qda oce ad]mj]gano bmjroc aacojm mecekojm 'DEDP(+ npkkjmodib a kjoeiodag mjge di EiPF hdbmaodji 'nee 8VOpbSr ,(1,(-(-Rcdn ran npbbenoe_ an ndagtgaodji rdoc oce eiuthe ei_jiepmjahdid_ane,L dioemaeme_ rdoc EiPF cegg hdbmaodji di qdqj 'Wjncd_a eo ag-+ 0884(-Rce haejmdot ja nop_den+ cjreqem+ npbbeno ij cgeam mjge ajm NQ?,LA?K di mebpgaodib EiPF hdbmaodji-Ucdge LA?K dn eskmenne_ agjib oce geiboc ja oce oemhdiag iemqe+ EiPF iepmjin jigt mehadi annjcdaoe_ rdoc oce oemhdiag iemqe agjib don he_dag kjmodji di Kacalpen 'Opai]ecf eo ag-+ 0886(-Dpmocem+ eqagpaodji ja LA?K ai_ LA?K,07/ ipgg hdce meqeage_ ij ndbidadcaio _dnmpkodji ja EiPF iepmji hdbmaodji-Rcene _dncmekaio menpgon hat caqe ]eei _pe oj oce me_pi_aict ja oce LA?K np]otke ntnoeh-,(0(-(, GlgQoQonXcUObSa WnQlcRWnU QSll acrTOQS UlgQoprobSWna Jdooge dn fijri a]jpo cjr bgtcjcjiepbaoen hat diagpeice eamgt EiPF hdbmaodji+ cjreqem+ do can ]eei mekjmoe_ ocao a cegg npmaace bgtcjcjiepbaoe+ cammtdib a gacojnahdie hjdeot+ diagpeicen EiPF iepmji hdbmaodji 'Bgenn eo ag-+ 1//0(-Rce bgtcjntgomainaemane ß0+2,L aceotgbgpcjnahditgomainaemane,0 'ß2EiR0( ad_e_ gacojnahdie a__dodji oj a np],kjkpgaodji ja EiPF ceggn ai_ ai eskmenndji kaooemi rdoc a keaf ao C02 ajggjre_ ]t a np]nelpeio _jrimebpgaodji ran cjindnoeio rdoc a mjge di mebpgaodib EiPF hdbmaodji-Kdce ipgg ajm ß2EiR0 _dnkgate_ ai accphpgaodji ja EiPF iepmjin di oce ianag cjhkamoheio ao C04+ ai_ a oei_eict ajm oce iepmjin ocao _d_ eioem oce ]madi oj ]e hdnoambeoe_ arat amjh oce qeiomag ajme]madi-Ckcmdin ame a bmjpk ja cegg npmaace hjgecpgen ocao ame regg fijri oj kgat a mjge di asji bpd_aice di hait amean ja ]madi _eqegjkheio 'Eah]ge eo ag-+ 1//4(-Ckcmdin ndbiag ocmjpbc oce heh]maie otmjndie fdiane mecekojmn Ckc? ai_ CkcB+ ai_ reme didodaggt dhkgdcaoe_ di EiPF hdbmaodji _pe oj a hpoaodji ocao menpgoe_ di a 56 f] _egeodji rdocdi oce Ckcmdi mecekojm Ckc?4-?n a cjinelpeice ja oce hpoaodji+ oce EiPF iepmjin ja ocene hdce jqemeskmenne_ Ckc?4+ menpgodib di ai a]ijmhag accphpgaodji ja EiPF iepmjin di oce ianag cjhkamoheio-Bpe oj oce 'cgphke_' iaopme ja EiPF ceggn ocao mehadie_ aooacce_ oj jgaacojmt asjin+ do ran ctkjocendne_ ocao jqemeskmenndji ja Ckc?4 capne_ dicmeane_ a_cendji oj oce asjin ai_ kmeqeioe_ ocedm hdbmaodji-Nceijotkdc aiagtndn ja oce a_pgo EiPF kjkpgaodji ajpi_ ocao jigt 01% ja oce iepmjin reme ajpi_ di oce ctkjocagahpn 'Eah]ge eo ag-+ 1//4(-?n Ckcmdin ai_ ocedm mecekojmn ame ]joc heh]maie,]jpi_ kmjoedin+ ndbiaggdib cai jigt jccpm ocmjpbc _dmeco cegg,cegg cjioacon+ npbbenodib ocao Ckcmdin ncjpg_ ]e eskmenne_ ]t TLL asjin-,(0(.(, C:A; (COaOl SmPrgonWQ AHGH TOQbor) LCJD ran didodaggt dnjgaoe_ amjh eskmenndji kmjadgdib ja hdbmaodib ai_ iji,hdbmaodib kmdhamt mj_eio EiPF iepmjin+ rdoc don eskmenndji gjcagdne_ oj oce heh]maien ja hdbmaodib EiPF ai_ jgaacojmt iepmjin 'Imahem % Umat+ 1///(-Rce eskmenndji kaooemi ja LCJD dn cdbcgt npkkjmodqe ja a mjge di mebpgaodib hdbmaodji ja ocene iepmjin an don eskmenndji dn _jrimebpgaoe_ rcei oce ceggn eioem oce ajme]madi-Iijcf_jri ja LCJD di eh]mtjidc es qdqj ianag eskgaio cpgopmen menpgoe_ di _ecmeane_ cjhkgesdot ja hdbmaodib jgaacojmt asjin ai_ a me_pcodji ja oce EiPF cegg kjkpgaodji ]t 22% 'Imahem % Umat+ 1///(dn oce ccdea dicd]dojmt iepmjomainhdooem ajpi_ di oce hahhagdai ALQ+ cganndcaggt apicodjidib oj me_pce iepmjiag escdoa]dgdot 'agocjpbc do dn escdoaojmt oj haopme EiPF iepmjin 'Acei % Kjeioem+ 1//8: Uaoaia]e eo ag-+ 1//8(-E?B? dn ntiocendne_ amjh bgpoahaoe ]t oce eiuthaodc acodqdot ja bgpoahaoe _ecam]jstgane 'E?B( ai_ don cj,aacojm ktmd_jsag kcjnkcaoe-Rce 56 fBa dnjajmh ja E?B 'E?B56( accjpion ajm 8/% ja E?B? ntiocendn di oce hpmdie ]madi 'Cg Kenodfart eo ag-+ 1/00(+ ai_ cjindnoeio rdoc oce ceoemjbeiedot ja oce EiPF iepmjiag kjkpgaodji amjpi_ 2/% ame E?B?embdc _pmdib _eqegjkheio 'Rj]eo eo ag-+ 0885a(-Mqemeskmenndji ja a E?B56 omainbeie oambeoe_ oj EiPF iepmjin menpgon di dicmeane_ _dnkemndji ja EiPF iepmjin di oce ajme]madi 'Febem eo ag-+ 1//2(+ rcdcc menpgoe_ di np],aemodgdot ja oce aehage kmjbeit-Ea_0 ,., 'oce beie eicj_dib E?B56( hdce _dnkgat a_qaice_ EiPF hdbmaodji amjh oce ianag kgacj_e ao C03-4+ cjreqem+ oce iejiaoag geocagdot ja ocene hdce kmecgp_e_ mekmj_pcodqe aiagtndn amjh ]edib cji_pcoe_ 'Jee eo ag-+ 1//7(-Gi es qdqj ianag eskgaion+ E?B? can agnj ]eei ncjri oj dicd]do oce hdbmaodji ja eh]mtjidc EiPF iepmjin 'Dpencfj eo ag-+ 0887(+ cjiadmhdib E?B?n acodjin di mebpgaodib EiPF hdbmaodji-,(0(/(, GlcbOmObS Egpoahaoe dn oce kmdicdkge escdoaojmt iepmjomainhdooem di oce qemoe]maoe iemqjpn ntnoeh+ accjpiodib ajm jqem 8/% ja ntiakodc cjiiecodjin di oce cphai ]madi 'meqdere_ ]t Keg_mph 1///(-Go can agnj ]eei rd_egt ncjri ocao bgpoahaoe kgatn ai dhkjmoaio mjge di mebpgaodib ma_dag hdbmaodji rdocdi oce ceme]eggph 'Ijhpmj % Pafdc+ 0882( ai_ iejcjmoes 'Becam eo ag-+ 0888(+ acodib ocmjpbc LKB? 'L,heoctg,B,ankamoaoe( mecekojmn oj mebpgaoe diomaceggpgam cagcdph geqegn 'Ijhpmj % Pafdc+ 0887(-?gocjpbc jigt a nhagg kmjkjmodji ja hdbmaodib EiPF iepmjin '∼4%( akkeam oj eskmenn LKB? mecekojmn+ don eskmenndji cai ]e ajpi_ agg agjib oce hdbmaojmt kaocrat _pmdib eh]mtjbeiendn+ ai_ omeaoheio ja es qdqj ]madi ngdcen aaoem C01-4 rdoc ai LKB? mecekojm aioabjidno menpgoe_ di ai dicmeane di EiPF ceggn ajpi_ di oce BBB '_jmnag ]ai_ ja Bmjca( ai_ NM? 'Qdhjidai % Fem]dnji+ 1//0(-Rcdn dn npbbenodqe ja Egpoahaoe ndbiaggdib ocmjpbc LKB? mecekojmn oj dicd]do oce adiag noek ja EiPF hdbmaodji amjh oce he_dag nekoph oj oambeo ctkjocagahdc amean-Gi cjiomano oj ocdn dicd]dojmt mjge ja LKB? mecekojm acodqaodji ji EiPF hdbmaodji+ ?KN? 'α,ahdij,2,ct_mjst,4,heoctg,3,dnjsaujgekmjkdjidc acd_( mecekojm ndbiaggdib akkeamn oj kmjhjoe EiPF hdbmaodji amjh ianag mebdjin+ an a omeaoheio rdoc ai ?KN? aioabjidno menpgoe_ di ai accphpgaodji ja EiPF iepmjin di oce ijne 'Qdhjidai % Fem]dnji+ 1//0(-,(0(/(-88K (8VolSQgaboYWnWn) AAI dn a kekod_e cjmhjie didodaggt ccamacoemdne_ ajm don mjge di capndib oce megeane ja ]dge ai_ _dbenodqe eiuthen amjh oce bagg]ga__em ai_ kaicmean-Go ndbiagn qda ENAPn+ ai_ fijcfjpo hdce ajm oce AAI,0P kjnnenne_ ai dicmeane_ iph]em ja hdbmaodib EiPF iepmjin ca_ eioeme_ oce]madi aodid eo ag-+ 1//3(-Rce acodjin ja AAI ame eskecoe_ oj ]e _dmeco an oce AAI,0P eskmenndji ran cjgjcagdne_ rdoc eh]mtjidc EiPF ceggn'Edacj]did eo ag-+ 1//6(- heh]em ja oce kganhdijbei mebpgaoe_ bmjroc aacojm aahdgt ocao+ qda don heh]maie otmjndie fdiane mecekojm Keo+ escd]don hdojbeidc+ hjojbeidc ai_ ccehjaoomacoaio kmjkemoden di iepmjiag ceggn 'Aaoji eo ag-+ 1///: Epodemmeu eo ag-+ 1//3: Qebamma eo ag-+ 1//5(-FED,di_pce_ ndbiaggdib melpdmen cgeaqabe ]t kganhdijbein npcc an odnnpe kganhdijbei+ 'oN?( ai_ pmjkganhdijbei 'pN?( jm cjabpgaodji aacojmn 'Lag_did eo ag-+ 0881: Kamn eo ag-+ 0882(-Ucdge

IOPlS 1 (

 1 did eo ag-+ 1//6(-Keo ndbiaggdib escd]don a gambe _ebmee ja 'cmjnn oagf' rdoc jocem otmjndie fdianen+ ENAPn ai_ hpgodkge _jcfdib kmjoedin -npbbenodib a kjoeiodag dioemacodji ja ocdn kaocrat rdoc neqemag jocem aacojmn fijri oj mebpgaoe EiPF hdbmaodji-,(0(0(, CSbrWn)988 (9SlSbSR Wn QolorSQbOl QOnQSr)Leomdin ame a beieodcaggt regg cjinemqe_ cgann ja gahdidi,megaoe_ kmjoedin ocao cai apicodji an edocem ccehjaoomacoaion jm ccehjmekeggaion di hpgodkge mebdjin ja oce _eqegjkdib ALQ 'Idggeei % Qt]dibcj+ 1//7(+ rdoc ocedm dhkjmoaice oj iepmjiag bpd_aice pi_emncjme_ ]t oce j]nemqaodjin di oce ieomdi _eadcdeio hdce ocao aadg oj ajmh oce cdkkjcahkag cjhhdnnpme jm oce cjmkpn4 'picj,jm_diaoe_,4( mecekojmn caqe ]eei ncjri oj omain_pce ieomdi ndbiaggdib+ rdoc SLA4 kmdicdkaggt dhkgdcaoe_ di mekpgndqe ndbiaggdib+ ai_ BAA di aoomacodqe ndbiaggdib 'meqdere_ ]t Kjjme+ 1//6: Qpi eo ag-+ 1/00(-?__dodjiaggt+ BQA?K 'Bjri nti_mjhe cegg a_cendji hjgecpge( can ]eei kmeqdjpngt cjiadmhe_ an a ieomdi mecekojm ocao eqjfen ccehjaoomacoaio menkjinen oj ieomdin di_ekei_eiogt ja BAA 'Jt eo ag-+ 1//7(-Rmaindeiogt cdbc eskmenndji ja BAA di oce mao jgaacojmt ntnoeh dn ajpi_ amjh C03,C07 'Bediem % Qmeoaqai+ 0888(+ rcdge BAA eskmenndji dn ajpi_ di rdocdi oce TLM+ TLL ai_ di a np], kjkpgaodji ja hdbmaodib EiPF ceggn di hdce 'Qccramodib eo ag-+ 1//0: Qccramodib eo ag-+ 1//3(-Rce eskmenndji ja BAA ran ajpi_ oj ]e _jrimebpgaoe_ ]ebdiidib ao C01+ npbbenodib ocao BAA hat ]e dhkjmoaio di oce didodag noaben ja EiPF hdbmaodji-Sndib GFA do ran _dncjqeme_ ocao BAA,., hdce caqe _dnmpkoe_ asjiag oambeodib ja oce TLL ai_ ceice EiPF hdbmaodji+ rdoc oce cap_ag ]maicc ja oce TLL aadgdib oj opmi qeiomaggt dioj oce ajme]madi ai_ menpgodib di a kaocrat ocao dinoea_ kmjbmenne_ dioj oce ceme]mag cjmoes 'Qccramodib eo ag-+ 1//0(-Rcdn menpgo ran kceijcjkde_ di oce ieomdi,0 hpoaio hdce 'Loi0,., ( di cjiomano oj SLA,4 hpoaion 'Sic4c2mch,., ( -rcj dinoea_ _dnkgate_ otkdcag _eqegjkheio ja oce EiPF ntnoeh 'Qccramodib eo ag-+ 1//3(-Rcene menpgon ame cjindnoeio rdoc oce d_ea oca oce ccehjaoomacodji ja BAA kjndodqe qjhemjianag asjin ]t a bma_deio ja ieomdi,0 bpd_en oce cap_ag ]maicc ja oce TLL+ di opmi mebpgaodib oce _dmecodji ja EiPF hdbmaodji oj oce qeiomag ajme]madi-Gi oce ccdcf eh]mtj+ aadgpme ja qeiomaggt _dmecoe_ hdbmaodji ja EiPF iepmjin ai_ ocedm hdnmjpodib oj oce _jmnjhe_dag ajme]madi ran di_pce_ ]t hdneskmenndji ja ieomdi,0 di a _jmnjcap_ag nekoag mebdji ieam oce ojk ja oce cjhhdnnpmag kgaoe 'Kpmafahd eo ag-+ 1/0/(+ cdbcgdbcodib oce eqjgpodjiamdgt cjinemqe_ iaopme ja ieomdi ndbiaggdib ji EiPF hdbmaodji-,(0(0(-HlWb-GoPo Qgdon ame necmeoe_ kmjoedin+ ]eno fijri an mekpgndqe asji bpd_aice cpen ocao ndbiag ocmjpbc oce omainheh]maie mecekojm Pj]j-Gi_ee_+ Pj]j eskmenndji dn melpdme_ ajm mekpgndji ja asjin amjh oce hd_gdie di ]joc dkndgaoemag asjin ocao ieqem cmjnn oce hd_gdie ai_ cjhhdnnpmag asjin ocao caqe agmea_t cmjnne_ 'Id__ eo ag-+ 0887(-Gi qemoe]maoen+ ajpm _daaemeio Pj]jn ai_ ocmee ngdon caqe ]eei d_eiodade_+ rdoc agg Pj]jn ncjri oj dioemaco rdoc ieomdi,0+ a mecekojm ja BAA 'Qoedi % Renndem,Jaqdbie+ 1//0(-Qgdon aco an mekeggeion ja _eqegjkdib jgaacojmt asjin 'Jd eo ag-+ 0888: Up eo ag-+ 0888( ai_ TLLn 'Agjpodem eo ag-+ 1//3: Nmdice eo ag-+ 1//8( bpd_dib ocedm eskmenndji oj oce jgaacojmt ]pg]-Qgdo1 ,., hpoaion _dnkgat a _egate_ hdbmaodji ja EiPF iepmjin ao eqemt odhe kjdio aiagtne_ kmeiaoaggt+ menpgodib di _ecmeane_ EiPF diiemqaodji ja oce he_dai ehdieice 'Aamd]jid eo ag-+ 1/01(-Ghkjmoaiogt+ ij eaaeco ja mehjqag ja Qgdo1 ji oce ojoag iph]em ja EiPF iepmjin ran j]nemqe_-Dgpjmenceice,acodqaoe_ cegg njmodib 'D?AQ( ja EiPF99EDN iepmjin ao C03-4 meqeage_ eskmenndji ja Qgdo1+ Pj]j0 ai_ Pj]j1 di hdbmaodib EiPF ceggn 'Aamd]jid eo ag-+ 1/01(-Iijcfjpo hdce ajm Pj]j0 ai_ Pj]j1 ncjre_ ij ndbidadcaio agoemaodjin oj oce _eqegjkheio ja oce EiPF ntnoeh+ cjreqem+ Pj]j2 ,., hpoaion reme a kceijcjkt ja Qgdo1 ,., hdce-Gi qdomj ccehjoacodc eskemdheion cjiadmhe_ oce nkecdadcdot ja Qgdo1 ndbiaggdib ocmjpbc Pj]j2 agjie oj mebpgaoe EiPF hdbmaodji-,(1 GnGH BWUrObWon Wn HcmOna OnR non-VcmOn prWmObSa Rce esoaio gdoemaopme _eoadgdib EiPF hdbmaodji di cphain dn pi_emnoai_a]gt nkamne-Ucdge oce beieodc haidkpgaodjin ai_ eskemdheion _encmd]e_ a]jqe ai_ ]egjr cjpg_ ieqem ]e kemajmhe_ ji cphain ajm eocdcag meanjin+ oce _daadcpgot npmmjpi_dib rjmfdib rdoc kmeiaoag cphai odnnpe can kmecgp_e_ eqei ndhkge aiaojhdcag j]nemqaodjin amjh aidhag hj_egn ]edib cjiadmhe_ di cphain-Djm dinoaice+ _j EiPF iepmjin hdbmaoe di a hdbmaojmt hann an dn _encmd]e_ di jocem nkecden> Bj ocet ajggjr RL jm TLL asjin> Gi nkdoe ja ocdn+ neqemag kakemn caqe _jcpheioe_ EiPF hdbmaodji di nhagg nahkgen ja kmeiaoag cphain ai_ iji,cphai kmdhaoen-,(1(1 ISrmWnOl nSrdS OnObomg Rce noai_am_dne_ ijheicgaopme ja oce cmaidag iemqen 'AL( G,VGG _emdqen amjh oce rjmf ja Qahpeg Rcjhan qji Qöhhemmdib '0664,072/(+ rdoc eacc iemqe iahe_ accjm_dib oj oce aioemdjm,kjnoemdjm 'mjnomj,cap_ag( gjcaodji ja ocedm cmaidag ajmahdia 'Kjjme eo ag-+ 1//5: Bmafe eo ag-+ 1/0/(-Mpond_e ja oce oeso]jjfn ocao oeacc aiaojht oj he_dcag nop_eion+ cjreqem+ do can gjib ]eei fijri ocao oceme esdnon a 02 oc AL+ njheodhen meaemme_ oj an AL,/ jm AL,L 'L kmenemqdib oce Jaodi _emdqe_ ijheicgaopme9 ipgga YijieZ+ an ij ompe ?ma]dc cjiceko ja / ran fijri oj oce Pjhain( _pe oj don kjndodjidib mjnomag oj oce jgaacojmt iemqe 'AL,G(-Go dn ijr cjhhjigt meaemme_ oj an oce oemhdiag iemqe iemqpn oemhdiagdn 'RL( _pe oj oce hjmkcjgjbdcag j]nemqaodjin ja Jjcd '08/4( d_eiodatdib ocao do ]maiccen di oce mebdji ja oce gahdiae oemhdiagdn-Rce aiaojht ja oce RL akkeamn ndhdgam di hait nkecden ai_ do dn mea_dgt qdnd]ge+ aooacce_ oj oce kda haoem ]eoreei oce jgaacojmt noagf ai_ oce mjnomag necodji ja oce jkodc ccdanh ';WUcrS 1.(-Go kannen ocmjpbc oce he_dag mebdji ja oce nomda jgaacojmda ai_ cjpmnen qda oce jm]doag npmaace ja oce amjioag gj]e+ rceme do kannen ocmjpbc oce cmd]mdajmh kgaoe ja oce eochjd_ ]jie epno cap_ag ai_ gaoemag oj oce cmdnoa baggd ai_ an ijoe_ ]t Jjcd+ kmjcee_n oj oce gahdia oemhdiagdn-Rce oemhdiag baibgdji+ gjcaoe_ ji oce oemhdiag iemqe ]egjr oce ajme]madi+ _dqd_en oce oemhdiag iemqe dioj orj nebheion9 ai esomacmaidag nebheio+ cjhkjne_ ja kmjcennen jmdbdiaodib amjh ceggn di oce qjhemjianag jmbai ai_ esoei_dib dioj oce oemhdiag baibgdji: ai_ ai diomacmaidag nebheio+ cjhkjne_ ja kmjcennen jmdbdiaodib amjh oce oemhdiag baibgdji an regg an qjhemjianag ceggn ai_ esoei_dib dioj oce ajme]madi-Rce apicodji ja oce RL hat ]e nkecden nkecdadc rdoc ]joc mekmj_pcodqe ai_ jgaacojmt apicodjin kjnopgaoe_+ cjreqem+ EiPF dhhpijmeacodqdot can ]eei ajpi_ di RL ad]men ai_ don baibgdji di hpgodkge qemoe]maoen dicgp_dib cphain 'meqdere_ ]t Tdgeinft 1/01(-Rcdn dn enkecdaggt ompe _pmdib eh]mtjidc _eqegjkheio+ rcei EiPF ceggn jpoiph]em iji,dhhpijmeacodqe EiPF ceggn rdocdi oce RL+ rdoc oce maodj meqemndib oj akkmjsdhaoegt 0904 ]t ]dmoc-;WUcrS 1.( 6nObomg oT bVS ORclb VcmOn bSrmWnOl nSrdS (IC)( Giaemdjm npmaace ja oce a_pgo cphai ]madi dggpnomaodib oce cjhkjieion ja oce jgaacojmt ntnoeh-Rce omaco ja oce RL gden he_dag oj oce omaco ja oce jgaacojmt iemqe 'MR( cjpmndib agjib oce npmaace ja oce btmd mecod-?ioemdjmgt+ do dn diodhaoegt annjcdaoe_ rdoc oce jgaacojmt ]pg] 'MB(-Ddbpme oafei amjh Idh eo ag-+ Bmadi Peneamcc 0888-Be]aoe cjiodipen an oj oce eh]mtjidc jmdbdi ja oce RL+ rdoc _aoa npkkjmodib ]joc LA 'Ucdogjcf eo ag-+ 1//2( ai_ ianag kgacj_ag jmdbdin 'Qccraiueg,Dpfp_a % Naaaa+ 0878: Umat eo ag-+ 0878( di _daaemeio nkecden-Leocemocegenn+ didodag mekjmon ji oce _eqegjkheio ja oce RL di cphain 'Neamnji 0830( ajpi_ ocao don ]maiccen di oce ianag cjhkamoheio ame hjme he_dag ai_ kmjajpi_ ocai ocjne ja oce jgaacojmt iemqe ]pi_gen+ cjpmndib ocmjpbc oce ianag nekoph rdoc ]maiccen di oce nekoag hpcjna (;WUcrS 1/)& an do hdbmaoen amjh ijne oj ]madi 'Opai]ecf eo ag-+ 0886(-Ucdge oce TLL ei_n di oce ?MB 'accennjmt jgaacojmt ]pg](+ oce RL kmjbmennen _eekem dioj oce oegeicekcagji ai_ cai ]e _dnodibpdnce_ amjh oce TLL ]t oce kmeneice ja baibgda agjib don cjpmne-Rj oce apocjmn fijrge_be+ ij hjgecpgam aacojm can ]eei ncjri oj nkecdadcaggt ga]eg ai_ _dnodibpdnc oce RL ai_ TLL ai_ do dn qemt gdfegt ocao di cphain+ iji,cphai kmdhaoen ai_ kemcakn agg qemoe]maoen ocao oce asjiag ncaaajg_ EiPF iepmjin pne oj hdbmaoe ame acopaggt ]maiccen ja oce RL-;WUcrS 1/( 6nObomg oT bVS SmPrgonWQ VcmOn bSrmWnOl nSrdS( '6( ? nccehaodc mekmeneioaodji ncjrdib a nekoag qder ja oce oemhdiag iemqe 'RL( di a nds,hjioc jg_ cphai ajeopn-Kj_dade_ amjh KcAjooem 0804-'7( Qekoag qder ja oce RL di a 34hh cphai ajeopn-Kj_dade_ amjh Neamnji 0830,(2 ErWmObSaQeqemag nop_den caqe kemajmhe_ ccamacoemdnaodjin ja EiPF hdbmaodji di ajeoag iji,cphai kmdhaoen+ oce Pcenpn Kacalpen Kacaca hpgaooa-Kacalpen caqe a benoaodji geiboc ja akkmjsdhaoegt 055 _atn 'an jkkjne_ oj 17/ _atn di cphain(-Gi ajeoag hacalpen+ EiPF, dhhpijmeacodqe ceggn reme admno _eoecoe_ ao 2/ _atn benoaodji'Opai]ecf eo ag-+ 0886( gjcagdne_ oj oce _jmnag jgaacojmt kgacj_e ai_ ao 25 _atn benoaodji 'Pjiiefgedq % Penfj+ 088/( gjcagdne_ oj oce ianag ekdocegdph ai_ iemqe ]pi_gen agjib oce kaoc ja oce RL rdocdi oce ianag mebdji-EiPF iepmjin reme admno j]nemqe_ rdocdi oce ]madi ao 2/ 'Opai]ecf eo ag-+ 0886( ai_ 27 _atn benoaodji 'Pjiiefgedq % Penfj+ 088/(+ hdbmaodib dioj oce ]madi agjib oce _jmnag npmaace ja oce jgaacojmt ]pg]n+ ai_ admno meacce_ oce aioemdjm ctkjocagahpn ao 3/ _atn benoaodji 'Pjiiefgedq % Penfj+ 088/(-Bt _at 36 oce haejmdot ja ceggn ca_ meacce_ oce NM?+ cjdicd_dib rdoc oce admno akkeamaice ja EiPF cegg ]j_den di oce KBF 'Pjiiefgedq % Penfj+ 088/(-Rce _daaemeicen di odhdibn j]nemqe_ hat ]e _pe oj oce aiodnema ehkgjte_ ]t oce orj bmjpkn+ rdoc Opai]ecf ai_ cjggeabpen podgdndib orj kmdhamt aiodnema 'JP,0 ai_ ED,5(-JP,0+ rcjne aiodbeidc _eoemhdiaio dn _dmecoe_ oj ahdij acd_n 1,3 ai_ 6,0/ ja EiPF0 'Qdgqemhai eo ag-+ 088/( ai_ ED,5 ocao ncjrn ai dicmeane_ aaadidot ajm ct_mjstg,kmj,EiPF0 rdoc a 83% cmjnn meacodqdot rdoc nea ]meah EiPF'Opai]ecf eo ag-+ 0886(-Rcet ajpi_ ocao oceme ran a kjkpgaodji ja ceggn ocao reme kjndodqegt ga]egge_ ]t ]joc aiodnema+ ai_ a kjkpgaodji ocao ran escgpndqegt ga]egge_ rdoc ED,5-Go ran ocdn ED,5'*(.JP,0',( kjkpgaodji ocao ran _eoecoe_ ao 2/ _atn benoaodji ai_ ceice reme _encmd]e_ an ©eamgt ceggn"+ rcdgno _jp]ge kjndodqe ceggn reme _encmd]e_ an ©gaoe ceggn"-Rcene eamgt ceggn pi_emreio cpbe kmjgdaemaodji amjh 0///,2/// ceggn ]eoreei 2/,21 benoaodjiag _atn+ dicmeandib oj akkmjsdhaoegt 0/+/// ceggn ao 23 _atn-Opai]ecf ai_ cjggeabpen agnj _eoadge_ a necji_+ _jmnag hdbmaojmt kaocrat ocao ran eqd_eio amjh 27 _atn benoaodji+ rcdcc ge_ oj a gambe kjkpgaodji ja esoma,ctkjocagahdc EiPF iepmjin-Rcene iepmjin reme ajpi_ ncaooeme_ ocmjpbcjpo oce dioemiag caknpge+ cap_aoe+ kpoahei+ bgj]pn kaggd_pn+ ai_ cgapnomph+ rcdge a gambe iph]em reme agnj ajpi_ cjiceiomaoe_ di oce ahtb_aga-Rcene iepmjin reme diqamda]gt pidkjgam ai_ kjnnenne_ a _daaemeio kaooemi ja noadidib amjh ctkjocagahdc EiPF iepmjin+ Rce apocjmn ijoe_ ]t cjhkamdib cjmjiaggt necodjie_ ajeopnen ocao oce hdbmaodji akkeame_ oj didodaggt jccpm mjnomag,cap_aggt+ ai_ aaoem 4/ _atn benoaodji kmjbmenn di a gaoemag,he_dag _dmecodji-Rcdn dn npkkjmoe_ ]t a nop_t ocao esahdie_ iepmjbeiendn di oce NM? ja maon pndib omdodaoe_ octhd_die apojma_djbmakct 'Batem % ?gohai+ 0876(-Rcet ajpi_ ocao gaoemag iepmjin _eqegjk neqemag _atn ]eajme he_dag iepmjin: ocao Amjudem ai_ cjggeabpen '1/00( agnj ajpi_ a raqe ja hdbmaodji di oce gaoemag,he_dag ankeco ajm oce JF? npbbenon ocao ocdn dn gdfegt ai eqjgpodjiamdgt cjinemqe_ heccaidnh ja ctkjocagahdc _eqegjkheio+ eqei da do dn teo oj ]e d_eiodade_ di ]eooem fijri hj_egn npcc an hdce-Gi oce C024 ajeopn+ oce gambeno iph]em ja gaoe EiPF iepmjin reme neei mjnomaggt di kemdcjhhdnnpmag amean+ oce _dabjiag ]ai_ ja Bmjca+ he_dag kmejkodc amea+ he_dag nekoag ipcgepn+ mebdjin amjpi_ oce gahdia oemhdiagdn+ ai_ oce jmbaiph qancpgjnph ja oce gahdia oemhdiagdn-Aap_aggt+ gaoe EiPF iepmjin reme neei di oce amcpaoe ipcgepn ai_ oce he_dai ehdieice 'Opai]ecf eo ag 0886(-Rcdn ran di accjm_aice rdoc oce eamgdem rjmf+ rdoc ij _daaemeice di EiPF _dnomd]podji ajpi_ ]eoreei 024 _atn benoaodji ai_ ]dmoc ai_ rdoc oce cdbceno cjiceiomaodji ja EiPF cegg ]j_den gjcaoe_ di oce gaoemag amcpaoe ipcgepn+ cap_ag oj oce he_dai ehdieice-Ma ijoe+ oce TLM ran pi_eoecoa]ge kano 4/ _atn benoaodji 'ctkjocendne_ ]t oce apocjmn oj ]e oce ndoe ja jmdbdi ja EiPF iepmjin di oce hacalpe(-Rcene orj rjmfn di_dcaoe hait ndhdgamdoden ]eoreei oce hdbmaodji kaooemi ]eoreei hdce ai_ hacalpen+ rdoc oce haejm escekodji ]edib di oce cgeam d_eiodadcaodji ja a _jmnag hdbmaojmt kaocrat+ menpgodib di neehdibgt ecojkdc kjkpgaodjin ja EiPF-;WUcrS 10( 9WabrWPcbWon oT SOrlg OnR lObS mWUrObWnU QSlla Wn mOQOqcS ToSbcaSa( '6-;( Aahema gpcd_a _mardibn mekmeneiodib cjmjiag necodjin nekamaoe_ ]t 14/ μh ja ajeoag hacalpen ao eh]mtjidc _at 51-'G-H( Namanabdooag necodjin nekamaoe_ ]t 0/// μh amjh C51 ajeopnen-Camgt EiPF ceggn ']gpe( reme ajpi_ di oce NM?+ nekoph+ nomdaoph+ ahtb_aga+ nomda oemhdiagdn+ dioemiag caknpge ai_ cgapnomph-Jaoe EiPF ceggn 'me_( reme ajpi_ di oce jgaacojmt ]pg]n+ NM?+ ctkjocagahpn ai_ kemdqeiomdcpgam mebdjin ja oce gaoemag qeiomdcge ai_ dioemqeiomdcpgam ajmahei-?]]meqdaodjin9 JT9 gaoemag qeiomdcge: A_9 cap_aoe: Npo9 kpoahei: Qek9 nekoph: BBB9 _jmnag ]ai_ ja Bmjca: MB9 jgaacojmt ]pg]: L?9 ipcgepn accph]ein: ?A9 aioemdjm cjhhdnnpme: ?KE9 ahtb_aga: NM?9 kmejkodc amea: GGG T9 2 m_ qeiomdcge: Rc9 ocagahpn: JF9 gaoemag ctkjocagahpn: MV9 jkodc ccdanh: GT D9 dioemqeiomdcpgam ajmahei: KBF9 he_dj]anag ctkjocagahpn: AL GG9 jkodc iemqe: EN9 bgj]pn kaggd_pn: ?O9 ceme]mag alpe_pco: FNA9 cdkkjcahkpn Ddbpme a_akoe_ amjh Opai]ecf eo ag-+ 0886 ,(3 HcmOna Rce hdbmaodji ja EiPF iepmjin di cphain can ]eei _jcpheioe_ di neqemag kakemn di ]joc kctndjgjbdcag ai_ kaocjkctndjgjbdcag cji_dodjin+ ceme dn nphhamdne_ oce adi_dibn amjh kctndjgjbdcaggt ijmhag ajeopnen+ rcdge kaocjgjbdcag cji_dodjin rdgg ]e cjind_eme_ di 8VOpbSr ,(1,(,-Go can gjib ]eei fijri ocao oce akkmjsdhaoe abe ja oce ajmhaodji ja oce kmdhamt kgespn ja oce ctkjocagahjctkjkctneag kjmoag qancpgaopme dn 03 EU+ ]po ocao oce cjiodipdot ja oce kmdhamt ai_ necji_amt kgespn can ijo ]eei _ehjinomaoe_ oj jccpm ]eajme 07,10 EU 'Cnkdianne 0822: Ldehdieqa 0838(-?ccjm_dibgt+ a hd_,benoaodji acodqaodji di EiPF acodqdot 'Ageheion eo ag-+ 0865: Iakgai eo ag-+ 0865( iecenndoaoen ocao oce amccdoecopme ja EiPF iepmjin nei_dib kmjeecodjin cjioacodib oce he_dai ehdieice ncjpg_ ]e di kgace ao ocdn odhe-Gi_ee_+ oce admno nop_den ocao esahdie_ EiPF eskmenndji _pmdib eamgt eh]mtjidc gdae jccpmme_ ]eajme oce _dncjqemt ocao oce ceggn amjne di ai esoma,eicekcagdc mebdji ai_ rcdge ocene nop_den d_eiodade_ EiPF eskmenndji kmeiaoaggt+ ocet jigt mekjmo eskmenndji di oce ctkjocagahpn-Djm dinoaice+ Napgdi ai_ cjggeabpen '0866( aiagtne_ 11 ajeopnen amjh 5,13 EU+ rdoc oce eamgdeno abe ja EiPF dhhpijmeacodqdot _eoecoe_ di oce ctkjocagahpn ao 8 EU+ cjreqem+ ij eskmenndji ran _eoadge_ di esomactkjocagahdc mebdjin-Qccraiueg,Dpfp_a ai_ cjggeabpen '0885( ajpi_ ocao ao 31 ']po ijo ao 17,21( _atn ja benoaodji+ EiPF dhhpijkjndodqe ceggn reme ajpi_ di oce ekdocegdph ja oce he_dag jgaacojmt kdo-?o ocdn noabe EiPF ran agnj ajpi_ agjib LA?K kjndodqe ad]men rcdcc akkeame_ oj ]p_ amjh oce ekdocegdph ja oce he_dag jgaacojmt kdo agjib rdoc oce baibgda ja oce RL ai_ rdoc ]maiccen ja oce RL cap_ag oj oce jgaacojmt ]pg]-?o 35 _atn benoaodji '5-4 EU( EiPF ceggn reme neei eioemdib oce ajme]madi rdoc asjin ja oce oemhdiag iemqe+ rcdge njhe ceggn cjpg_ agmea_t ]e _eoecoe_ di oce he_dag ]anag ajme]madi-Rce apocjmn ijoe_ ocao oce TLL ai_ RL cjpg_ ]e _dnodibpdnce_ ijo jigt ]t ocedm _daaemeiodag eiomaice kjdion dioj oce _eqegjkdib ]madi+ ]po agnj ]t oce kmeneice ja a ]gjj_ qenneg ocao nekamaoe_ oce gaoemag+ jgaacojmt iemqe _emdqe_ kjmodji ja oce ncaaajg_ amjh oce he_dag+ TLL,RL nebheio-Rce _eqegjkheio ja oce LA?K kjndodqe ncaaajg_ ran neei oj ]ebdi an eamgt an 17,21 _atn kjno jqpgaodji+ rdoc adie ad]men ai_ aancdcgen ajmhdib a ieorjmf di oce ianag heneiccthe+ kmece_dib oce jiojbeiendn ja EiPF iepmjin-Bt 31 _atn benoaodji+ LA?K kjndodqe ad]men reme ajpi_ ocmjpbc oce eiodme hdbmaojmt mjpoe+ amjh oce ekdocegdph ja oce jgaacojmt kdo oj oce qeiomag ajme]madi-Opdioji ai_ cjggeabpen '0886( esahdie_ orj ajeopnen ja 03,05 EU+ cjiadmhdib oce kmeqdjpn mekjmon ocao ao ocdn odhe+ EiPF dhhpijmeacodqdot dn kmeneio amjh oce cmd]mdajmh kgaoe oj oce ctkjocagahpn+ agocjpbc ocet aadge_ oj adi_ ait EiPF eskmenndib ceggn nodgg di oce ianag cjhkamoheio ao 05 EU-,(3(1 ESrapSQbWdSa Rce gdhdoe_ rjmf nop_tdib EiPF hdbmaodji di kmdhaoen ai_ cphai ajeopnen can aggjre_ neehdibgt bjj_ cjmmegaodji rdoc oce cpi_me_n ja kakemn cjhkgeoe_ di hdce-Gi agg nkecden+ do dn cgeam ocao EiPF iepmjin jmdbdiaoe amjh a ndhdgam mebdji ai_ hdbmaoe agjib ai asjiag ncaaajg_ ja TLL.RLn oj meacc oce ]madi-Simecjicdge_ _daaemeicen agnj akkeam oj esdno cjreqem+ ajm dinoaice di oce oambeodib ja EiPF iepmjin oj esomactkjocagahdc amean di oce kmdhaoe-?gocjpbc ocdn kaocrat can ieqem ]eei _ehjinomaoe_ di cphain+ do dn gdfegt ocao do esdnon an EiPF0 hPL? eskmenndib ceggn ame ajpi_ di gambe iph]emn jpond_e ja oce ctkjocagahpn di a_pgo cphai ]madin 'Paice eo ag-+ 0883(-,(1* HgpoUonORobropWQ HgpoUonORWam Bpe oj don api_aheioag mjge di didodaodib kp]emoag jineo ai_ ceice bjia_ag apicodji qda bjia_jomjkdi necmeodji+ a]emmaodjin di oce _eqegjkheio ja oce EiPF ntnoeh api_aheioaggt menpgo di diaemodgdot nti_mjhen-Gi cphain+ oce aadgpme ja aclpdmdib nespag cjhkeoeice _pe oj a gacf ja ceiomag EiPF+ ajmh a maibe ja cgdidcag _dnjm_emn ocao ame ]mja_gt oemhe_ ctkjbjia_jomjkdc ctkjbjia_dnh 'FF( 'Qehdiama eo ag-+ 0887(-Rce kmeqageice ja FF dn _daadcpgo oj accpmaoegt _eoemhdie _pe oj oce kceijotkdc ceoemjbeiedot Ycjibeidoag 'AFF( jm aclpdme_Z ai_ neqemdot 'cjhkgeoe jm kamodag(-?n oce EiPF asdn dn acodqaoe_ ncjmogt aaoem ]dmoc Ya kceijheiji mecjbidne_ di ]joc hdce ai_ cphain+ cagge_ hdid,kp]emot 'Ipdmd,Faiidiei eo ag-+ 1/00a: 1/00](Z ocdn cai kmjqd_e oce admno jkkjmopidot oj d_eiodat a _tnmebpgaodji ja oce ei_jcmdie ntnoeh-Gi hagen+ hdcmjkeidn ai_.jm cmtkojmccd_dnh cai ]e npbbenodqe ja FF ai_ cjmhjiag kmjadgdib ja JF+ DQF+ oenojnoemjie 'Kadi eo ag-+ 1///( ai_ dicd]di B '?i_emnnji eo ag-+ 0886( ]eoreei oce 3 oc ai_ 7 oc reefn ja gdae cai ajmh ai eaaecodqe _dabijnodc ojjg 'Baeoain eo ag-+ 1/03(-Udoc ij npcc qdmdgdnaodji ja aehage beidoagda nj eamgt di kjno,iaoag _eqegjkheio+ _dabijndn dn hpcc hjme ccaggeibdib+ rdoc hdid, kp]emot geqegn ja cdmcpgaodib DQF ajpi_ oj ]e oce jigt ehkdmdcaggt heanpma]ge aacojm a]ge oj kme_dco FF-Aanen _dabijne_ ocdn eamgt ame escekodjiaggt mame ai_ dinoea_ oce haejmdot ja _dabijnen jccpm amjpi_ jm aaoem kp]emot+ rcei acodqaodji ja oce mekmj_pcodqe asdn ]ebdin di apgg-Rce a]neice ja cganndcag esoemiag ccaiben j]nemqe_ _pmdib kp]emot npcc an _eqegjkheio ja oce ]meanon ai_.jm aheijmmcea di aehagen ai_ _eqegjkheio ja oce oenoen.nespag apicodji di hagen ame cjhhji cjhkgadion amjh a_jgenceion rdoc AFF-Sinpmkmdndibgt kaodeion jaoei kmeneio rdoc dhkadme_ kntccjnespag _eqegjkheio+ _dnojmoe_ nega,]j_t dhabe+ gjr nega,enoeeh ai_ di mame canen bei_em _tnhjmkcda 'Brtem eo ag-+ 1/03(-Bdabijndn ja ompe FF iecenndoaoen jocemrdne ijmhag ctkjkctneag apicodji+ _eoemhdidib ocao EiPF _eadcdeict dn oce mjjo capne ja diaemodgdot-Agdidcag omeaoheio ja FF _ekei_n ji oce abe ja _dabijndn ai_ ceice don eskecoe_ bjagn-Camgt _dabijndn di ]jtn jaoei menpgon di admno omtdib oj di_pce hage nespag ccamacoemdnodcn ]t meqemndib ait aiaojhdcag aeaopmen ocao hat dhkaco gjib oemh aemodgdot 'npcc an cmtkojmccd_dnh( rdoc npmbemt a_qjcaoe_ ]eoreei 5,01 hjiocn 'Pdouei eo ag-+ 1//6: Acai eo ag-+ 1/03(-Jjr _jne oenojnoemjie jm bjia_jomjkdi mekgaceheio ocemakt hat agnj ]e ehkgjte_ oj di_pce keidge bmjroc di oce cane ja hdcmjkeidn rdoc oce a__dodjiag ]eieado ja DQF nodhpgaodib bjia_ag _eqegjkheio 'Brtem eo ag-+ 1/02(-Mie caqeao dn ocao ocene omeaoheio kmjojcjgn agocjpbc neehdibgt njpi_+ ame nodgg di ocedm megaodqe diaaict ai_ ij gjib,oemh jpocjhen cai teo ]e _eoemhdie_-Bpmdib a_jgenceice+ omeaoheio adhn oj di_pce qdmdgdnaodji ai_ ijmhag nespag apicodji+ ai_ kmjqd_e kntccjgjbdcag npkkjmo oj ocjne npaaemdib amjh _tnhjmkcdan-Qes noemjd_ mekgaceheio ocemakden 'oenojnoemjie di ]jtn+ jenoma_djg ajggjre_ ]t cjh]die_ jenoma_djg ai_ kmjbenoemjie di bdmgn( ame pne_ oj didodaoe kp]emot-Go ncjpg_ agnj ]e oafei dioj accjpio ocao rdocjpo omeaoheio+ FF kaodeion rcj _j ijo didodaoe kp]emot di a odhegt haiiem aadg oj eskemdeice a bmjroc nkjpo ai_ dinoea_ ]j_t ndue dicmeanen di a gdieam aancdji+ gea_dib oj oce epipccjd_ kmjkjmodjin ja oce Aanomaod an ijoe_ eamgdem-?n oce kp]emoag rdi_jr 'oce odhe rcei kp]emoag _eqegjkheio cai jccpm( dn iammjr+ a odhegt _dabijndn ai_ didodaodji ja omeaoheio dn enneiodag-Renojnoemjie omeaoheio ocao jccpmn aaoem oce kp]emoag rdi_jr can ncpo+ otkdcaggt aadgn oj di_pce bjia_ag haopmaodji ai_ ceice aemodgdot+ eqei rcei oambeoe_ oj oce cdbc ei_ ja ijmhag maibe 'Wjpib eo ag-+ 1/01(-?goemiaodqe akkmjaccen caqe ]eei cji_pcoe_ pndib kpgnaodge EiPF mekgaceheio+ jm bjia_jomjkdi mekgaceheio ja cphai ccjmdjidc bjia_jomjkdi 'FAE( di cjh]diaodji rdoc DQF+ ]joc rdoc oce dioeiodji ja nodhpgaodib bjia_ag apicodji-?ijocem dhkjmoaio cjind_emaodji ajm omeaoheio dn cjiodipe_ ]jie ceagoc+ an dn oce cane di agg _dnjm_emn rdoc a me_pcodji di bjia_ag noemjd_n-Gi_ee_+ neqemag mekjmon ja FF _dabijndn caqe amdnei amjh a_pgo kaodeion kmeneiodib oj oce cgdidc rdoc jnoejkjmjodc oei_eicden-Go dn dhkjmoaio oj ijoe ocao agocjpbc _dnmpkodji oj oce eh]mtjidc hdbmaodji ja EiPF iepmjin cai menpgo di diaemodgdot+ oce capne ja _dnmpkodji hat ]e cjhkges ai_ ijo ndhkgt eskgadie_ ]t aacojmn ocao ame diomdindc oj mebpgaodib ocdn kmjcenn-Qeqemag cphai diaemodgdot nti_mjhen ame dinoea_ ocjpbco oj amdne amjh _dnmpkodji ja kmjcennen diqjgqe_ di bpd_dib oce asjin ocao bpd_e oce hdbmaodib ceggn+ cagge_ Iagghai Qti_mjhe 'IQ(-,(11 8onUSnWbOl HgpoUonORobropWQ HgpoUonORWam (8HH) Ajibeidoag ajmhn ja FF 'AFF( caqe a hage kmeqageice ja 2,4 oj 0 'Qehdiama eo ag-+ 0887: Kdoccegg eo ag-+ 1/00( ai_ ame fijri oj escd]do a gambe _ebmee ja ceoemjbeiedot pkji cgdidcag _dabijndn-Ajhkges nti_mjhen ocao dicgp_e edocem AFF jm IQ dicgp_e ]po ame ijo gdhdoe_ oj9 cjh]die_ kdopdoamt cjmhjie _eadcdeict+ nekoj,jkodc _tnkganda+ AF?PEC nti_mjhe+ a_meiag ctkjkganda cjibeidoa rdoc FF+ Uaam_ei]pmb nti_mjhe+ Bam_eo,Bdeg nti_mjhe ai_ Ejm_ji Fjghen nti_mjhe 'nee Bjech eo ag-+ 1/04(-AFF dn ijr cjhhjigt accekoe_ oj ]e ai jgdbjbeidc _dnjm_em rdoc qamda]ge keieomaice ai_ npmkmdndibgt+ ]eoreei 0/,1/% ja AFF kaodeion pi_embj nkjioaiejpn mecjqemt ja aemodgdot -dicgp_dib kaodeion rdoc fijri hpoaodjin di AFF annjcdaoe_ beien-Rcdn npbbenon a npmkmdndib ahjpio ja apicodjiag kganodcdot cai jccpm di mebpgaodib oce FNE asdn+ rdoc ij fijri cjmmegaodib jm kme_dcodji aacojmn-Peceio a_qaicen di jpm pi_emnoai_dib ja oce aacojmn cjiomd]podib oj AFF caqe gambegt ]eei _pe oj oce a_qeio ja ieso beiemaodji nelpeicdib 'LEQ( oeccijgjbden+ cjiadmhdib don kmdnhaodc iaopme ai_ menpgoe_ di oce ajmhaodji ja a Cpmjkeai cjinjmodph ja meneamccemn ai_ cgdidcdain di 17 cjpiomden nop_tdib EiPF ]djgjbt 'cjineinpn noaoeheio9 Bjech eo ag-+ 1/04(-Qeqemag fijri AFF hpoaodjin dicgp_dib DED7+ DEDP0 ai_ QCK?2? ame agnj fijri oj _dmecogt mebpgaoe ]jie hann 'Kdmajpd eo ag-+ 1/00: Fatancd eo ag-+ 1/01( rcdcc ncjpg_ ]e oafei dioj accjpio ]t cgdidcdain annenndib gjib oemh omeaoheio jkodjin rdoc ocedm kaodeion cam]jpmdib ocene hpoaodjin-Ucei _dabijne_ di a odhegt haiiem+ AFF dn acopaggt jie ja oce aer hage diaemodgdot _dnjm_emn ocao dn omeaoa]ge rdoc bjj_ kme_dcodqe jpocjhen-? apgg gdno ja agg AFF annjcdaoe_ beien d_eiodade_ dn nphhamdne_ di IOPlS 1-,(1, KOllmOnn HgnRromS Iagghaii nti_mjhe 'IQ( dn _eadie_ an AFF annjcdaoe_ rdoc aijnhda _pe oj a cjh]diaodji ja a]ijmhag hdbmaodji ja EiPF iepmjin ai_ oambeodib ja jgaacojmt asjin oj oce kmenphkodqe jgaacojmt ]pg]n _pmdib _eqegjkheio 'Qccraiueg,Dpfp_a % Naaaa+ 0878: Qehdiama eo ag-+ 0887(-Go otkdcaggt jccpmn di amjpi_ 4/% ja cgdidcaggt mekjmoe_ AFF canen-IQ cai ]e _daadcpgo oj _dnodibpdnc cgdidcaggt amjh AFF jm ABEN 'cjinodopodjiag _egat ja bmjroc ai_.jm kp]emot(-?ijnhda an _eoecoe_ ]t cgdidcag jgaacodji oenon+ an regg an jgaacojmt ]pg] ctkjkganda.akganda an _eoemhdie_ ]t KPG cai ]e pneapg _dabijnodc ojjgn-Rce cji_dodji ran didodaggt _encmd]e_ ]t Bm Kaenome _e Qai Hpai '0745( rcj j]nemqe_ oce a]neice ja jgaacojmt iemqen di a ctkjbjia_dc di_dqd_pag pkji kjno,hjmoeh esahdiaodji-Rce nti_mjhe dn iahe_ cjreqem+ aaoem Dmaiu Iagghaii rcj d_eiodade_ a ceme_doamt ctkjbjia_dc nti_mjhe annjcdaoe_ rdoc aijnhda 'Iagghaii eo ag-+ 0833(+ rcdge Qccraiueg,Dpfp_a % Naaaa '0878( reme oce admno oj kmjqe ocao ctkjbjia_dnh amdnen _pe oj a aadgpme ja EiPF hdbmaodji-IQ dn cpmmeiogt enodhaoe_ oj caqe a kmeqageice ja 0 di 7+/// di hei ai_ 0 di 3/+/// di rjhei+ abadi _dnkgatdib a nes ]dan an neei di AFF 'Aamd]jid % Kabbd+ 1//5(-Rce oma_dodjiag Kei_egdai qder ja hjijbeidc dicemdoaice ja IQ can meceiogt ]eei jqemopmie_+ oj ]ecjhe caoebjmdne_ an ai jgdbjbeidc _dnjm_em caqdib a cjhkges aeodjgjbt 'Qtfdjodn eo ag-+ 1/0/(-Rcdn meqdndji can cjhe an hpoaodjin di hjme ocai jie beie caqe ]eei mekjmoe_ di neqemag IQ cane mekjmon diqjgqdib _daaemeio cjh]diaodjin ja beien+ rdoc jgdbjbeidc dicemdoaice cpmmeiogt ocjpbco oj accjpio ajm 0/,1/% ja cgdidcag canen-Qeqemag beien caqe hjme amelpeiogt ]eei annjcdaoe_ oj _dbeidc dicemdoaice kaooemin-Gi neqemag canen oce nebmebaodji kaooemi ja ocene _dbeidc.jgdbjbeidc hpoaodjin rdocdi oce aahdgt ke_dbmee cai accjpio ajm oce kceijotkdc qamda]dgdot ]eoreei aahdgt heh]emn 'Qtfdjodn eo ag-+ 1/0/(-Gi a__dodji+ oce jgaacojmt ai_ mekmj_pcodqe _eaecon hat ]e cjh]die_ rdoc jocem _dnjm_emn jm naoeggdoe nthkojhn+ dicgp_dib9 meiag abeidndn+ ntifdiendn 'hdmmjm hjqeheio(+ nti_acotgt+ cmaidjaacdag a]ijmhagdoden+ cjgjh]a ai_ neinjmdiepmag _eaaienn-Kait ja ocene annjcdaoe_ _dnjm_emn cai ]e omace_ oj eh]mtjidc aiaojht+ ajm dinoaice+ dhkmjkem _eqegjkheio ja oce jgaacojmt ai_ jodc kgacj_en-Ucao ajggjrn dn a fet nphhaodji ja neqemag dhkjmoaio beie aahdgden ocao caqe ]eei _eadidodqegt kmjqei oj capne IQ di cphain-Rce admno IQ annjcdaoe_ beie oj ]e _dncjqeme_ ran iahe_ aaoem oce nti_mjhe donega+ ]ecjhdib fijri an Iag0 'Bjne % Qamha+ 0864(-Iag0+ ijr meaemme_ oj an ?ijn0 '_e Aanomj eo ag-+ 1/05(+ ran admno _eoecoe_ _pe oj a beieodc gendji ao Vk11-2 ai_ ran _eadidodqegt gjcaoe_ oj oce V ccmjhjnjhe 'Epdjgd eo ag-+ 0880: Fam_egdi eo ag-+ 0880(-Rcdn kjndodjidib ajmhn ai V,gdife_ hj_e ja dicemdoaice rdoc cdbc keieomaice+ kamodaggt eskgadidib oce dicmeane_ kmeqageice ja IQ di hei cjhkame_ oj rjhei-?ijn0 eicj_en ?ijnhdi,0+ a 57/,ahdij acd_ necmeoe_ esomaceggpgam haomds bgtcjkmjoedi-Bdjccehdcaggt ?ijnhdi,0 acon an a cegg a_cendji kmjoedi ocao kgatn ai dhkjmoaio mjge _pmdib _eqegjkheio ja oce eiodme ALQ+ rdoc don a]neice menpgodib di agoeme_ asjiag kaocadi_dib+ cjggaoemagdnaodji ai_ ceggpgam hdbmaodji-Peceiogt ?ijn0 hpoaodjin caqe agnj ]eei _encmd]e_ di hpgodkge ncgemjndn canen '_e Aanomj eo ag-+ 1/03(+ rdoc a meceio mekjmo ja hpgodkge ncgemjndn di a Iagghaii kaodeio 'Kaioemj eo ag-+ 1/05(-Kpoaodjin di ?ijn0 di IQ menpgo di ammenoe_ EiPF hdbmaodji ao oce geqeg ja oce cmd]mdajmh kgaoe 'Dmaicj eo ag-+ 0880: Jebjpdn eo ag-+ 0880: Qccraiueg,Dpfp_a % Naaaa+ 0878: Resedma eo ag-+ 1/0/(-Rj _aoe ij cjhjgjb ja ?ijn0 can ]eei d_eiodade_ di mj_eion+ kmeqeiodib oce beieodc haidkpgaodjin ai_ apicodjiag di qdqj oenodib ocao rjpg_ pnpaggt ]e kjnnd]ge-,(1,(, 6rrSabSR GnGH mWUrObWon Wn VcmOn ToSbcaSa Gi nkdoe ja oce megaodqe mamdot ja IQ ai_ nti_mjhen ja jgaacojmt ]pg] ctkjkganda 'npcc an omdnjht 02(+ orj ajeopnen rdoc fijri hpoaodjin di ?ijn0+ jie AF?PEC ajeopn ai_ jie omdnjht 02 ajeopn caqe ca_ ocedm EiPF hdbmaodji kaooemi aiagtne_-?kkmjsdhaoegt 1.2 ja AF?PEC nti_mjhe canen ame capne_ ]t iejhpoaodjin di AFB6 'Tdnnemn eo ag-+ 1//3( ai_ hpoaodjin di ocdn beie caqe ]eei d_eiodade_ di IQ kaodeion 'Hjibhain eo ag-+ 1//8: Idh eo ag-+ 1//7( npbbenodib jqemgakkdib _eqegjkheioag capnen-;WUcrS 11( GnGH mWUrOborg proQSaa Wn normOl OnR KOllmOnnma agnRromS ToSbcaSa( Qccehaodc Bdnomd]podji ja EiPF-0-dhhpijmeacodqe ceggn 'me_ _jon( di oce amjiojianag mebdji ai_ ajme]madi ja ijmhag cphai ajeopnen '5-7 reefn jg_( ai_ di ajeopnen rdoc Iagghaii'n nti_mjhe-Apmqe_ gdien di_dcaoe oce kaoc ja oce jgaacojmt 'teggjr gdien( ai_ qjhemjianag.oemhdiag iemqe ad]men ']gpe gdien(-Gi cjiomjg ajeopnen ao 5-7 reefn ja benoaodji+ EiPF eskmenndib ceggn ame _dnomd]poe_ agg agjib oce hdbmaojmt mjpoe amjh oce amjiojianag mebdjin oj oce kmenphkodqe ctkjocagahpn-Gi IQ ajeopnen+ EiPF ceggn accphpgaoe agjib oce _dncjiodipe_ kaoc ja jgaacojmt ai_ oemhdiag iemqe ad]men ocao _j ijo hafe cjioaco rdoc oce ajme]madi-Ddbpme oafei amjh Edacj]did N Dmjiodemn di Lepmjei_jcmdijgjbt 1/04-? meceio nop_t esahdie_ rceocem ctkjbjia_dnh di AF?PEC kaodeion+ an regg an oce a]neice ja jgaacojmt ]pg]n ajpi_ di njhe di_dqd_pagn rdoc omdnjht 02 ai_ omdnjht 07 hat menpgo di _eaecodqe hdbmaodji ja EiPF an di oce ?ijn0 ajeopn 'Resedma eo ag-+ 1/0/(-Rcdn ran accdeqe_ ]t esahdidib a 14 EU hage ajeopn cammtdib a ijineine hpoaodji di ?ijn0+ a 12 EU hage cammtdib a amahe,ncdao hpoaodji di AFB6+ ai 07 EU aehage rdoc omdnjht 02 '36+ VV*02 famtjotke( ai_ a 24 EU hage rdoc omdnjht 07 '36+ VW*07(-Gi agg ammcdieicekcagdc ajeopnen+ ij EiPF ceggn reme ajpi_ di oce NM? jm ctkjocagahpn+ rcdge iphemjpn EiPF cegg ]j_den reme ajpi_ cjiadie_ oj oce ianag mebdji ai_ oce _jmnag ankeco ja oce cmd]mdajmh kgaoe+ jccandjiaggt ajmhdib cgpnoemn di oce baibgdji ja oce RL-Ghkjmoaiogt+ di 1 cjiomjg ajeopnen '11 ai_ 13 EU(+ EiPF ceggn iphemjpngt kjkpgaoe_ oce ajme]madi ai_ ij EiPF ceggn reme ajpi_ di oce ianag mebdji jm di cjioaco rdoc oce cmd]mdajmh kgaoe-?__dodjiaggt+ ]joc oce AFB6 ai_ ?ijn0 ajeopnen kjnnenne_ ]dgaoemag nompcopmen ji oce _jmnag ankeco ja oce cmd]mdajmh kgaoe cjindnoeio rdoc iepmjhan di_dcaodib ai eioaibgeheio ja iemqe ad]men+ rcdge ndhdgam ]pgben reme j]nemqe_ ieso oj oce cmdnoa baggd di ai a__dodjiag EU 02 ammceieicekcagdc ajeopn ';WUcrS 12(-Rcene nompcopmen ame mehdidnceio ja oce kceijotke ja Nmjfm1 ,., hdce 'Ndooegjp_ eo ag-+ 1//6(-;WUcrS 12( 6rrSabSR GnGH mWUrObWon Wn VcmOn pObVoloUWSa( Ajmjiag necodjin ja oce amjiojianag mebdji di oce I?J0 ajeopn ai_ 12,reef,jg_ omdnjht 02 ai_ cjiomjg ajeopnen+ dhhpijnoadie_ ajm βGGG,op]pgdi Gi oce I?J0 ai_ omdnjht 02 ajeopnen+ ]dgaoemag nkcemdcag nompcopmen cjmmenkji_dib oj iepmjhan 'ammjrcea_n( ame qdnd]ge ji oce _jmnag ankeco ja oce cmd]mdajmh kgaoe 'ck(-':lH( Ajmjiag necodjin cjmmenkji_dib oj oce ]jse_ mebdjin di B-Gi agg ajeopnen+ EiPF0 ceggn reme neei di oce pkkem ianag mebdji 'mebdji 0( ai_.jm ji oce _jmnag ankeco ja oce cmd]mdajmh kgaoe 'mebdji 1(-Ljoe oce kmeneice ja EiPF0 ceggn jigt ji oce _jmnag ankeco ja oce cmd]mdajmh kgaoe ajm oce 24,reef,jg_ omdnjht 07 ajeopn-Qcage ]amn9 0 hh '6l9(: 1// μh '9+ dineo(: 2/ μh ':lH(-Qccehaodc mekmeneioaodjin ja oce _dnomd]podji ja EiPF ceggn di ijmhag ai_ kaocjgjbdcag _eqegjkheio ame agnj dicgp_e_-?]]meqdaodjin9 je9 jgaacojmt ekdocegdph-Ddbpme oafei amjh Resedma eo ag-dn enneiodag oj hpgodkge ankecon ja qemoe]maoe ai_ diqemoe]maoe eh]mtjidc _eqegjkheio+ aibdjbeiendn+ rjpi_ ceagdib+ ai_ odnnpe cjhejnoandn-DEDP0 dn oce kmdicdkge mecekojm ocao he_daoen DED ndbiaggdib acodib di cjiepicodji rdoc heh]maie annjcdaoe_ cekamdi npgkcaoe kmjoejbgtcain-DEDP0 eskmenndji can ]eei d_eiodade_ di oce ianag kgacj_e+ _eqegjkdib jgaacojmt ]pg]n ai_ dn eskmenne_ agjib oce EiPF hdbmaojmt kaocrat ai_ ]t EiPF iepmjin ocehnegqen 'Idh eo ag-+ 1//7(-DED agnj kgatn ai enneiodag mjge di oce hjmkcjbeiendn ja oce oegeicekcagji dicgp_dib oce jgaacojmt ]pg]n-DEDP0 can ]eei ncjri oj ]e enneiodag ajm EiPF hdbmaodji ai_ hpoaodjin di DEDP0 ame fijri oj capne apojnjhag _jhdiaio ajmhn ja ]joc IQ ai_ ijmhjnhdc AFF 'Idh eo ag-+ 1//7: Vp eo ag-+ 1//6(-?gocjpbc DEDP0 hpoaodjin ame oce necji_ hjno cjhhji hjgecpgam capne ja IQ ocpn aam d_eiodade_+ don hpoaodjin ame fijri oj caqe a rd_e kceijotkdc qamda]dgdot -npbbenodqe ja dicjhkgeoe keieomaice ai_ jgdbjbeidcdot 'Bdaicj % Iadnem+ 1//8(-DED7+ jie ja oce gdbai_n ja DEDP0+ dn agnj annjcdaoe_ rdoc IQ ai_ AFF 'Dagam_eap eo ag-+ 1//7(-Rce hpoaodjin d_eiodade_ di DED7 di kaodeion reme qagd_aoe_ di qdomj ai_ di ndgdcj rdoc ]joc akkmjaccen npbbenodib _egeoemdjpn eaaecon ji DED7 ndbiaggdib 'Dagam_eap eo ag-+ 1//7(-Dpmocemhjme+ hdce cjhjutbjpn ajm a ctkjhjmkcdc Dba7 aggege gacfe_ EiPF iepmjin di oce ctkjocagahpn+ rcdge ceoemjutbjpn hdce ncjre_ np]noaiodag _ecmeanen di oce iph]em ja EiPF iepmjin ai_ ctkjocagahdc EiPF kekod_e cjiceiomaodji-?__dodjiaggt+ DED06 rcdcc ncamen a nomjib nelpeice d_eiodot rdoc DED7 'Kdmajpd eo ag-+ 1/02(+ can agnj ]eei ncjri oj ]e ai dhkjmoaio acodqaojm ja DEDP0 ndbiaggdib ocao hat cjiomd]poe oj IQ 'Kdmajpd eo ag-+ 1/02(-Kdmajpd ai_ cjggeabpen agnj d_eiodade_ neqemag hpoaodjin di GJ06PB+ a beie eicj_dib a heh]em ja oce dioemgepfdi,06 mecekojm kmjoedi aahdgt-Rcdn aahdgt ajmhn kamo ja a gambem bmjpk fijri an QCD 'ndhdgam eskmenndji oj DEDn(+ rdoc GJ06PB ncjri oj dioemaco rdoc DEDP0 di omainaecoe_ cphai eh]mtjidc fd_iet cpgopmen-Rce di qdqj eskmenndji kaooemi ja GJ06PB dn npbbenodqe ja a mjge di oce eamgt noaben ja EiPF aaoe nkecdadcaodji-Gioemenodibgt do can ]eei ncjri ocao ?ijnhdi,0 cai aco an a hj_pgaojmt cj,gdbai_ rdoc DED7 oj acodqaoe DEDP0+ di a haiiem _ekei_eio ji oce kmeneice ja cekamai npgkcaoe 'Rjmi]emb eo ag-+ 1/00(-Qeqei hpoaodjin di oce FQ5QR0 'cekamai npgkcaoe 5,M,npgaomainaemane eiuthe( beie caqe ]eei d_eiodade_ di AFF kaodeion rdoc qamtdib geqegn ja jgaacojmt apicodji 'Rjmi]emb eo ag-+ 1/00( apmocem di_dcaodib oce dhkjmoaice ja DED ndbiaggdib di oce jiojbeiendn ja EiPF _eqegjkheio-Qehakcjmdin ame necmeoe_ jm heh]maie annjcdaoe_ bgtcjkmjoedin ocao cjioadi a cjinemqe_ 3// ahdij acd_ 'Qeha' _jhadi ai_ ame regg ccamacoemdne_ bpd_aice hjgecpgen ocao ame kctgjbeieodcaggt cjinemqe_ acmjnn nkecden amjh iehaoj_en ai_ dinecon oj qemoe]maoen+ dicgp_dib cphain-3 cgannen ja nehakcjmdin caqe ]eei d_eiodade_ di qemoe]maoen+ rdoc cgann 2 nehakcjmdin ]edib necmeoe_ ai_ cgannen 3,6 ]edib heh]maie ]jpi_-Rce kmdhamt mecekojmn he_daodib nehakcjmdi ndbiaggdib ame iepmjkdgdin 'Lmk0 ai_ Lmk1( ai_ kgesdin-Qehakcjmdin reme didodaggt ccamacoemdne_ ajm ocedm mjge di he_daodib asji bpd_aice _pmdib _eqegjkheio ]po meceio rjmf can gea_ oj oce d_eiodadcaodji ja nehakcjmdin di a rd_e maibe ja kmjcennen npcc an mebpgaodji ja cegg a_cendji ai_ hjodgdot+ aibdjbeiendn+ dhhpie menkjinen ai_ ophjpm kmjbmenndji 'Aanauua eo ag-+ 1//6: Ajhjbgdj eo ag-+ 1//3: Impbem eo ag-+ 1//4: Kaii eo ag-+ 1//6: Kaii ai_ Pjpbji+ 1//6: Lepaeg_ ai_ Ienngem+ 1//7: Nanoemfahk ai_ Edbem+ 1//8(-Rce cgann,2 necmeoe_ nehakcjmdin ]di_ oj iepmjkdgdin+ rcdcc aco an gdbai_,]di_dib cj, mecekojmn-Lepmjkdgdi,1 ipgg 'Lmk1 ,., ( hdce caqe a 14% me_pcodji di oce ojoag EiPF kjkpgaodji _pmdib a_pgocjj_+ rcdge agnj caqdib ai dicmeane di oce iph]em ja iepmjin mend_dib di oce ianag nekoph 'Aamd]jid eo ag-+ 1//6( -npbbenodib a _eaeco di hdbmaodji-Rcdn ran npbbenoe_ oj jccpm _pe oj a _eaandcpgaodji ja oce qjhemjianag asjin+ _dnmpkodib oce kaocrat agjib rcdcc EiPF iepmjin hdbmaoe-Aamd]jid ai_ cjggeabpen '1/0/( agnj d_eiodade_ mjgen ajm Qeha2a pndib beieodc hjpne hj_egn-Qeha2a ,., hdce _dnkgat neqeme _eaecon di qjhemjianag kmjeecodjin menpgodib di aghjno cjhkgeoe a]neice ja EiPF dhhpijmeacodqdot di oce ajme]madi ao C03-4 ai_ C07-4-Rce qagd_dot ja ocene adi_dibn di hdce ran cjiadmhe_ di 1/01 rcei orj bmjpkn d_eiodade_ gacf ja apicodji hpoaodjin di Qeha2a di IQ nti_mjhe kaodeion 'Faiccaoe eo ag-+ 1/01: Wjpib eo ag-+ 1/01(-Ma ijoe+ neqemag ja oce hpoaodjin d_eiodade_ ]t Faiccaoe ai_ cjggeabpen reme agnj ajpi_ di cgdidcaggt piaaaecoe_ di_dqd_pagn+ npbbenodib ocao ocene hpoaodjin cjiomd]poe oj oce jgdbjbeidc ajmhn ja IQ-Lepmjkdgdi0 'Lmk0( dn ai j]gdbaojmt cj,mecekojm ja Qeha2a ai_ don eskmenndji _egdieaoen oce EiPF hdbmaojmt kaocrat+ dicgp_dib oce cap_ag ]maicc ja oce TLL di ]joc hdce ai_ cphain 'Faiccaoe eo ag-+ 1/01(-Kdce gacfdib apicodjiag nehakcjmdi ndbiaggdib ocmjpbc Lmk0 'Lmk0 neha.neha ( jm Lmk1 ,., jigt kamodaggt kceijcjkt oce _eaecon ja Qeha2a ,., hdce+ rcdge oce cjhkjpi_ hpoaio Lmk0 neha.neha :Lmk1 ,., hdce _dnkgat a cjhkama]ge kceijotke oj Qeha2a fijcfjpon-Rce ijmhag _dnomd]podji ai_ kjkpgaodji ndue ja EiPF iepmjin di a_pgo cji_dodjiag hpoaio hdce gacfdib Lmk-0 jigt di EiPF iepmjin 'EiPF99Ame:Lmk0 gjsN.gjsN hdce( 'Faiccaoe eo ag-+ 1/01( apmocem cjiadmhn ocao oce _eaecodqe hdbmaodji ja EiPF iepmjin di ocene eh]mtjn dn _pe oj oce a]ijmhag mjpodib ja TLLn dioj oce qeiomag ajme]madi-Rafei ojbeocem ocdn npbbenon ocao Qeha2a ndbiaggdib diqjgqdib ]joc Lmk0 ai_ Lmk1 cjiomjgn qjhemjianag asji oambeodib oj oce ]madi ai_ ocao don _dnmpkodji menpgon di hdbmaojmt _eadcdon ocao ame ijo cegg apojijhjpn 'di_dmecogt aaaecodib EiPF hdbmaodji(-Rcdn ran di cjiomano oj Qeha2a ,., hdce ocao ca_ ijmhag EiPF _eqegjkheio+ npbbenodib ocao ijo agg necmeoe_ Qehakcjmdin ame melpdme_ ajm TLL oambeodib-? ncame_ kjdio hpoaodji di Qeha2e can ]eei d_eiodade_ di a aahdgdag cane ja IQ 'Aamd]jid eo ag-+ 1/04(-Gioemenodibgt+ di cjiomano oj oce regg ccamacoemdne_ mjgen ja necmeoe_ nehakcjmdin di mebpgaodib asji bpd_aice+ Qeha2e ran ncjri oj dinoea_ mebpgaoe npmqdqag ja EiPF iepmjin ocmjpbc dioemacodjin rdoc Ngesdi B0 'Aamd]jid eo ag-+ 1/04(-Ma ijoe+ oce amaoemiag Qeha2e hpoaodjin cj,nebmebaoe_ rdoc a hpoaodji di AFB6 ai_ a _e ijqj hpoaodji di Qeha2e ran a__dodiaggt d_eiodade_ di a cjcjmo ja AF?PEC kaodeion 'Jagaid eo ag-+1//3(+ apmocem npkkjmodib kamodaggt ncame_ _eqegjkheioag aeodjgjbden ja ocene nti_mjhen-Qeha3B dn a omainheh]maie,]jpi_ nehakcjmdi ocao dn kmjoejgtodcaggt cgeaqe_ oj ]di_ Ngesdi B0 ai_ Keo otmjndie fdiane mecekojm 'Ajimjooj eo ag-+ 1//4(-Rcdn dioemacodji otkdcaggt he_daoen bmjroc cjie cjggakne ja _eqegjkdib asjin ai_ di_pcen ccehjoasdn 'Bemdecf eo ag-: Bedecf eo ag-+ 1/0/: Xcjp eo ag-+ 1//7(-Qeha3B eskmenndji ajmhn a bma_deio di oce eh]mtjidc ianag mebdji+ rdoc a cdbcem cjiceiomaodji ao oce geqeg ja oce LD].H+ npbbenodib do acon n a ccehjaoomacoaio ajm hdbmaodib EiPF ceggn+ rcdcc ran np]nelpeiogt cjiadmhe_ di qdomj 'Edacj]did eo ag-+ 1//7(-?__dodjiaggt+ Qeha3B ipgg hdce ame np]aemodge 'Baclpdi eo ag-+ 1/00(-Qeha3B+ agjib rdoc don cdbc aaadidot mecekojmn NgesdiB0 ai_ NgesdiB1 ame cdbcgt eskmenne_ di oce _eqegjkdib jgaacojmt ntnoeh+ rdoc Ngesdi B0 eskmenndji ajpi_ di oce ianag kgacj_e ai_ cj,gjcagdndib rdoc LA?K kjndodqe ad]men ao C01-4-Lj eskmenndji ja NgesdiB0 ran _eoecoe_ di edocem TLL jm di EiPF iepmjin ocehnegqen ao C03-4 jm C06-4 -npbbenodib a cdbcgt gjcagdne_ eaaeco eamgt di EiPF hdbmaodji 'Edacj]did eo ag-+ 1//7(-Rcdn d_ea ran cjiadmhe_ pndib ai es qdqj ianag eskgaio cpgopme rceme NgesdiB0 ran _eoecoa]ge di eamgt cegg _dqdndjin+ ai_ ceane_ oj ]e eskmenne_ di gaoem _dqdndjin-NgesdiB0 ipgg hdce escd]do a _eaeco di oce hdbmaodji ja EiPF iepmjin+ ocao menpgon di a _ecmeane di oce ojoag kjkpgaodji ndue di oce a_pgo ]madi-Qeha6? ndbiagn ocmjpbc NgesdiA0 ai_ β0,dioebmdi rdoc ocedm eskmenndji kaooemin cdbcgt npbbenodqe a mjge di mebpgaodib EiPF hdbmaodji-Qeha6? dn cdbcgt eskmenne_ di oce ianag kdo ai_ agjib oce TLL _pmdib eh]mtjidc _eqegjkheio+ rcdge oce eskmenndji ja don mecekojmn dn nkaodjoehkjmaggt mebpgaoe_ rdocdi hdbmaodib EiPF iepmjin 'Kenndia eo ag-+ 1/00(-?o eamgt hdbmaojmt noaben+ EiPF iepmjin nkecdadcaggt eskmenn β0,dioebmdi+ rcemean ocet ]ebdi oj eskmenn NgesdiA0 jice ocet meacc oce ei_ ja ocedm hdbmaojmt ejpmiet-Rcdn dn cjindnoeio rdoc di qdomj eskemdheion ocao _ehjinomaoe_ ocao Qeha6a nodhpgaoen dicmeane_ _dmecodjiag hdbmaodji di dhhjmoagdne_ EiPF ceggn _ekei_eio ji β0,dioebmdi ndbiaggdib+ rcdgno jqemeskmenndji ja NgesdiA0 cagoe_ ocedm hdbmaodji 'Kenndia eo ag-+ 1/00(-Gi qdqj cjiadmhaodji ja Qeha6? ndbiaggdib di oce mebpgaodji ja EiPF hdbmaodji cahe amjh aiagtndn ja hpoaio hdce+ rdoc Qeha6? _eadcdeio ai_ cji_dodjiag diacodqaodji ja β0,dioebmdi di EiPF iepmjin menpgodib di a me_pcodji di oce a_pgo EiPF kjkpgaodji+ an regg an me_pce_ bjia_ag ndue ai_ np]aemodgdot 'Kenndia eo ag-+ 1/00: Namfanc eo ag-+ 1/01(-Kdnneine hpoaodjin di Qeha6? caqe ]eei d_eiodade_ di ]joc AFF ai_ IQ kaodeion 'Iäinäfjnfd eo ag-+ 1/03(+ agocjpbc an ]joc kaodeion rdoc Qeha6? hpoaodjin reme agmea_t d_eiodade_ oj kjnnenn hpoaodjin di fijri AFF.IQ annjcdaoe_ beien 'ajm esahkge jie kaodeio kjnnenne_ a hpoaodji di ?ijn0(+ do ran cjicgp_e_ ocao Qeha6? hpoaodjin agjie rjpg_ ]e pigdfegt oj ]e npaadcdeio oj beiemaoe a apgg IQ kceijotke-;WUcrS 13( IVS rolS oT HSmOpVorWn aWUnOllWnU Wn rSUclObWnU GnGH mWUrObWon( '6( Qccehaodc mekmeneioaodji ja oce cea_ ja a hjpne eh]mtj ao C03-4 _ekdcodib oce ncaaajg_ ajmhe_ ]t oce jgaacojmt iemqe 'ML( ai_ qjhemjianag.oemhdiag iemqe 'TLL.RL(+ agjib rcdcc EiPF ceggn hdbmaoe amjh oce ijne oj oce qeiomag ajme]madi-'7( Bdaaemeio nehakcjmdin eskmenne_ di oce _eqegjkdib ianag mebdji-'8( Keccaidnhn ja acodji ja oce nehakcjmdin ji EiPF iepmji hjodgdot ai_.jm iaqdbaodji agjib TLL.RL-?]]meqdaodjin9 je9 jgaacojmt ekdocegdph: qij9 qjhemjianag jmbai: ih9 ianag heneiccthe: i.a] e9 ianag.ajme]madi epicodji: aj]9 accennjmt jgaacojmt ]pg]: hj]9 hadi jgaacojmt ]pg]: qa]9 qeiomag ajme]madi-Kj_dade_ amjh Edacj]did Dmjiodemn di Lepmjei_jcmdijgjbt 1/04 ,(1,(. ESrapSQbWdSa Rce np]nelpeio d_eiodadcaodji ja hpoaodjin di IQ kaodeion+ ajggjrdib ccamacoemdnaodji ja EiPF hdbmaojmt _dnmpkodji di hdce hj_egn pi_emgdien oce qagd_dot ja ocdn akkmjacc oj d_eiodatdib kjoeiodag AFF.IQ beien-?i Gioemiaodjiag cjinjmodph ja kctndcdain ai_ ncdeiodnon nop_tdib AFF ai_ IQ ran ajmhe_ di 1/01+ rdoc oce adh oj makd_gt a_qaice jpm pi_emnoai_dib ja oce hait capnen ja ocene mekmj_pcodqe nti_mjhen ai_ omaingaoe ocene _dncjqemden dioj dhkmjqe_ kaodeio came-Rcdn acodji cpghdiaoe_ di oce cjineinpn noaoeheio 'Bjech eo ag-+ 1/04( ocao nphhamdne_ oce meceio a_qaicen ocao ca_ ]eei ha_e-? apgg gdno ja agg oce fijri AFF ai_ IQ beien ocpn aam d_eiodade_ dn kmeneioe_ di IOPlS 1+ rdoc ocedm mjgen di mebpgaodib EiPF _eqegjkheio ai_.jm apicodji nphhamdne_ di ;WUcrS ,*-;WUcrS ,*( HQVSmObWQ oT Ynoen TOQbora QonbrWPcbWnU bo 8HH (QonUSnWbOl VgpoUonORobropWQ VgpoUonORWam) AFF dn a hpgodaacojmdag+ jgdbjbeidc _dnjm_em rceme _dnmpkodji oj EiPF ndbiaggdib cai jccpm _pe oj _eqegjkheioag a]ijmhagdoden jm di mamem canen ]e aclpdme_ kjnoiaoaggt-Rcdn nccehaodc mekmeneion hait beien fijri oj capne _eaecodqe EiPF megeane di kjnoiaoag gdae+ ai_ agnj ao rcao geqeg ocet aco oj mebpgaoe kamo ja EiPF kctndjgjbt-Ddbpme oafei amjh cookn9..fagghaiinti_mjhe-rjm_kmenn-cjh. GSnSa Ynoen bo QonbrWPcbS bo 8HH OnR KH ?B9 ?pojnjhag Bjhdiaio: ?P9 ?pojnjhag Pecenndqe: AFF9 cjibeidoag ctkjbjia_jomjkdc ctkjbjia_dnh: AF?PEC9 Ajgjh]a+ ceamo _eaecon+ aomenda ja ccjaiae+ meoam_aodji ja bmjroc+ beidoag ai_ jm pmdiamt _eaecon+ eam aijhagden jm _eaaienn: ANFB9 cjh]die_ kdopdoamt cjmhjie _eadcdeict: EFQ9 Ejm_ji Fjghen Qti_mjhe: FQ: Famonadeg_ nti_mjhe: KEQ9 hjmidib bgjmt nti_mjhe: MKGK9 jigdie Kei_egdai dicemdoaice di hai: NCNLQ9 kjgtei_jcmdie _eadcdeicden ai_ kjgtiepmjkaocden: QFDK9 nkgdo,cai_.ajjo hagajmhaodji: QMB9 nekoj,jkodc _tnkganda: UQ9 Uaam_ei]pmb nti_mjhe

-( 1 1 ?-

 11 HSfcOl 9SdSlopmSnb " 9WTTSrSnbWObWonQespag _daaemeiodaodji dn a kmjcenn ocao ]ebdin _pmdib oce ajeoag kemdj_ ai_ cjiodipen di oce iejiaoe ai_ ocmjpbc kp]emot+ gea_dib oj oce enoa]gdncheio ja nespag _dhjmkcdnh-Rce beieodc nes ja hahhagn dn _eoemhdie_ ao aemodgdnaodji ai_ _ekei_n ji oce iaopme ja oce nes ccmjhjnjhen kjnnenne_ ]t oce di_dqd_pag-Gi hahhagn+ oce _eaapgo kmjbmahhdib ja jpm beien ccamon a cjpmne ajm aehage _eqegjkheio+ rdoc oce kmeneice ja oce W ccmjhjnjhe di hei ]edib oce fet ndbiag oj capne _dqembeice di oce kaocn-Pebam_genn+ cjreqem+ ja don ccmjhjnjhag cemdoabe+ eacc di_dqd_pag rdgg bj ocmjpbc a nespaggt pi_daaemeiodaoe_ kceijotke _pmdib eamgt ajeoag gdae-Rce enoa]gdncheio ja nes dn a cjhkges kceijheiji+ _eoemhdie_ ]t oce _daaemeiodag eskmenndji ja cmdodcag beien _pmdib a ]mdea rdi_jr di ]joc hagen ai_ aehagen-Rce haejm _eqegjkheioag noaben gea_dib oj hage jm aehage nespag _daaemeiodaodji ame qemt ndhdgam acmjnn hahhagn+ eqei di Rjfp_ada jndheindn+ oce Ptpfp nkdit mao+ ocao can gjno don W ccmjhjnjhe ai_ QPW 'nes,_eoemhdidib mebdji W( beie 'Moafe % Ipmjdra+ 1/05(-Rce d_ea ja a oenodcpgam aacojm mebpgaodib oce nespag _daaemeiodaodji ja oce bjia_n ran kmjkjne_ ajggjrdib j]nemqaodjin ha_e ]t ?game_ Hjno di 0836-Fe ajpi_ ocao oce Küggemdai _pcon ja oce ma]]do rjpg_ di_ekei_eiogt _daaemeiodaoe dioj oce aehage mekmj_pcodqe ntnoeh 'iahegt oce poempn+ aaggjkdai op]en ai_ pkkem orj,ocdm_n ja oce qabdia( di oce a]neice ja oenodcpgam necmeodjin 'Hjno+ 0836(-Djggjrdib bjia_ecojht ja nespaggt pi_daaemeiodaoe_ ma]]don+ Hjno bmaaoe_ edocem jqamdai jm oenodcpgam odnnpe dind_e oce ma]]don ai_ rdoienne_ oce cjmmeco _eqegjkheio ja edocem oce aehage jm hage beidoagda menkecodqegt-Rce kama_dbh ncdaodib eskemdheio cahe rcei+ ajggjrdib bjia_ecojht+ ce dhkgaioe_ a oenojnoemjie kmjkmdjiaoe cmtnoag agjie+ ijodib ocao rcdgno oce Ujgaadai _pcon reme nodhpgaoe_ oj _eqegjk+ oceme ran ij mebmenndji ja oce Küggemdai _pconcdbcgdbcodib ocao a oenodcpgam aacojm jocem ocai oenojnoemjie ran menkjind]ge ajm bjia_ag _daaemeiodaodji-Hjno cagge_ ocdn aacojm ©cjmhjie dicd]domdce" jm ©dicd]doepm hüggemdai" 'Hjno 0842(+ ai_ oj_at do dn ]eooem fijri an aiod,Küggemdai cjmhjie jm Küggemdai dicd]dodib np]noaice '?KF+ KGQ(-Sexual development and differentiation 0/KF ran admno kpmdade_ di 0873 ]t dhhpijccmjhaojbmakct 'Ndcam_ % Hjnnj+ 0873( ai_ nelpeicdib ja ]joc cphai ai_ ]jqdie ajmhn ajggjre_ ncjmogt ocemeaaoem 'Aaoe eo ag-+ 0875: Ndcam_ eo ag-+ 0875(-Rce kmeneice ja ai ?KF beie dn esomehegt regg cjinemqe_ ocmjpbc eqjgpodji+ ]edib kmeneio di aghjno agg hahhagn 'Kpinoem]emb % Jjqegg,Ba_be+ 0880: Fall eo ag-+ 0881: Jac]d],Kainadn eo ag-+ 0886: Nanf eo ag-+ 1//3(+ ccdcfei 'Mmeag eo ag-+(+ mekodgen 'Uenoemi eo ag-+ 0888(+ hamnpkdagn 'Nanf eo ag-+ 1//3(+ ue]maadnc 'Qccpgu eo ag-+ 1//6( ai_ ahkcd]dain '?g,?naa_ eo ag-+ 1/02(-?gg ame ajmhe_ ja adqe esjin+ rdoc oce cdbceno _ebmee ja cjhjbeiedot ]edib j]nemqe_ ]eoreei esjin 1,4 ]eoreei agg nkecden ocpn aam nop_de_-?KF dn a bgtcjkmjoedi '_eoadge_ _dncpnndji ja don nompcopme di HSQbWon -(/( ajpi_ di oce ]gjj_+ npbbenodib do can a cjmhjiag apicodji-Rce kmdhamt njpmcen ja kmj_pcodji+ d_eiodade_ nj aam+ ame oce Qemojgd ceggn ja oce oenoen ai_ oce bmaipgjna ceggn ja oce jqamden-Fjreqem+ ?KF eskmenndji can agnj ]eei _eoecoe_ di oce ]madi ai_ kmjnoaoe+ an regg an di jocem kemdkcemag odnnpen+ npcc an gpibn 'Ja Kamca eo ag-+ 1//4: Jjib eo ag-+ 1///: Epnoaanji eo ag-+ 0882(-Qemph ?KF geqegn ame esomehegt cdbc _pmdib hage kmeiaoag _eqegjkheio: cjreqem+ ndbidadcaio geqegn di aehagen ame ijo kmeneio piodg kp]emot rceme ocet mdne oj akkmjsdhaoegt oce nahe geqeg neei di hagen ∼1/kK ';WUcrS ,1(-?n rdoc agg cjmhjien ocao ame eskmenne_ di a nespaggt _dhjmkcdc aancdji+ dioemeno can ajcpne_ ji ccamacoemdndib oce oehkjmag kaooemin ja don eskmenndji+ oceme]t aggjrdib diaemeicen oj ]e ha_e an oj kjnnd]ge kctndjgjbdcag apicodjin '_eoadge_ _dncpnndji di mekmj_pcodqe mjgen ja ?KF necodji( Rce beiemag geqegn ja _eoecoa]ge ?KF di nemph ocmjpbcjpo hage ai_ aehage gdae-?KF geqegn ame aghjno 1/s cdbcem di kmeiaoag ]jtn cjhkame_ oj ait kjnoiaoag abe di edocem hagen jm aehagen-Gi ?KF geqegn ame beiemaggt cdbcem di hagen ocai aehagen rdoc ndhdgam geqegn ajpi_ jigt amjh oce hd_,oeein oj oce ei_ ja oce ocdm_ _eca_e-Rce eskmenndji geqeg di aehagen dn cjindnoeio rdoc a mekmj_pcodqe mjge an geqegn dicmeane ocmjpbc kp]emoag teamn ai_ ocei ]ebdi _ecmeandib an heijkapne akkmjaccen-Ljoe oce W asdn can ]eei nkgdo-?_akoe_ amjh ?_ahn L 1/01 Gi qemoe]maoen+ oce _eqegjkheio ja oce pmjbeidoag akkamaopn 'dicgp_dib oce fd_ietn+ bjia_n+ ]ga__em ai_ pmdiamt ai_ mekmj_pcodqe _pcon( ]ebdin ncjmogt aaoem banompgaodji ]t oce _daaemeiodaodji ja oce dioemhe_daoe henj_emh-Rcdn nompcopme rdgg didodaggt kmjgdaemaoe ai_ njhe ceggn pi_embj a omaindodji amjh heneiccthag ceggn oj ekdocegdag ceggn oj ajmh oce apopme hage ai_ aehage mekmj_pcodqe nompcopmen 'Ij]atancd ai_ Becmdibem 1//2(-Qpcc do dn+ ocao _pmdib kamo ja eh]mtjidc _eqegjkheio+ eqemt di_dqd_pag kjnnennen ]joc hage ai_ aehage mekmj_pcodqe _pcon ai_ ocpn can oce kjoeiodag oj _eqegjk a hage jm aehage mekmj_pcodqe ntnoeh-Gi jm_em ajm ijmhag hage jm aehage _eqegjkheio oj jccpm+ jie ja oce orj kadmn ja _pcon hpno mebmenn ai_ oce jocem hpno _eqegjk-Rce pi_daaemeiodaoe_ dioemiag beidoag omaco dicgp_en oce Ujgaadai ai_ oce Küggemdai _pcon-Bjoc ajmh kamo ja oce henjiekcmjn ai_ esoei_ agjib ocedm cap_ag ei_ oj ejdi oce pmjbeidoag ndipn gea_dib oj oce beidoag op]emcge 'oce jmdbdi ja oce beidoag omaco(-Rce Ujgaadai 'henjiekcmdc( _pcon ame admno ajpi_ agjib oce eh]mtjidc fd_iet ai_ cai _daaemeiodaoe oj ajmh a _pco+ ekd_d_thdn ai_ nehdiag qendcgen-Gi hdce+ oce Ujgaadai _pcon ame apggt ajmhe_ ao C0/-4-Rce Küggemdai 'kamahenjiekcmdc( _pcon _eqegjk aioemj,kjnoemdjmgt agjib oce Ujgaadai _pcon ]eoreei C00-4 ai_ C02-4 di hdce ai_ caqe oce kjoeiodag oj _eqegjk dioj jqd_pco+ poempn ai_ pkkem qabdia-

  oce Küggemdai _pcon ame neindodqe oj ?KF dn C03,C04+ rdoc mebmenndji kmjbmenndib amjh C03,C05 'Ndcji+ 0858: Rnped eo ag-+ 0881(-Gi cphain+ oce mebmenndji can ]eei mekjmoe_ oj ]e cjhkgeoe_ ]t benoaodjiag reef 8 'Rabpccd eo ag-+ 0873(+ eqei ocjpbc jpm bmjpk meceiogt mekjmoe_ ocao do hdbco acopaggt oemhdiaoe gaoem+ amjpi_ EU01 'Begge eo ag-+ 1/06(-Gi aehagen rceme bjia_ag ?KF geqegn ame ijo _eoecoa]ge kmeiaoaggt+ oce Ujgaadai _pcon dinoea_ mebmenn+ aggjrdib oce _eqegjkheio ja oce aehage mekmj_pcodqe omaco-;WUcrS ,,( BOmmOlWOn aSf RWTTSrSnbWObWon( ?gg hahhagn _eqegjk a ]dgaoemag kadm ja Küggemdai ai_ Ujgaadai _pcon _pmdib eh]mtjidc _eqegjkheio-Rcene nompcopmen ame oce aigabei ja oce aehage ai_ hage mekmj_pcodqe omacon menkecodqegt ai_ ompe nespag _daaemeiodaodji melpdmen oce mebmenndji ja jie kadm ai_ oce _eqegjkheio ja oce jocem-Rce kmeneice ja a W ccmjhjnjhe di hagen nodhpgaoen oce megeane ja ?KF ai_ oenojnoemjie amjh oce kmdhdodqe oenodn+ rcdcc aco oj capne mebmenndji ja oce Küggemdai _pco _pmdib a iammjr+ cmdodcag rdi_jr ja eh]mtjidc _eqegjkheio-Gi oce a]neice ja a W ccmjhjnjhe ai_ ceice a oenodn oj necmeoe ?KF ai_ oenojnoemjie+ aehage bjia_ag _eqegjkheio jccpmn kanndqegt rdoc oce apojhaodc _ebeiemaodji ja oce Ujgaadai _pcon aggjrdib oce Küggemdai _pcon oj _daaemeiodaoe ai_ _eqegjk dioj oce aehage mekmj_pcodqe omaco-Peaemeice9 Kaoupf % Jah]+ Laopme Ke_dcdie 1//7

  jqamt-Dpmocemhjme+ ?KF ran ncjri oj enoa]gdnc cjhkges dioemmegaodjin rdoc caijidcag DQF mebpgaojmn ocao ame agnj kamo ja oce REDβ aahdgt npcc an BKN1-;WUcrS ,/ GnGH nScrona SfprSaa 6BHG, bVrocUVocb lWTS( '6-8( Ajiajcag dhaben ja hpmdie EiPF iepmjin 'bmeei( ao C01-4 ocao eskmenn ?KFP1-'me_( rdoc Fjeccno an a ipcgeam cjpioemnoadi ']gpe(-'9-I( Ghaben amjh oce a_pgo MTJR ncjrdib EiPF ai_ ?KFP1 cj,gjcagdnaodji-'J-B( Ajiajcag dhaben ja a cphai ajeopn ao 7 benoaodjiag reefn noadie_ ajm EiPF ai_ ?KFP1-'C-E( Ghaben amjh ai a_pgo cphai ncjrdib EiPF iepmjin agnj eskmenn ?KFP1 kjnoiaoaggt-Ddbpme oafei amjh Adhdij eo ag-+ Laopme Lepmjncdeice 1/05

1 -

 1 Rjoag iph]emn ja EiPF ceggn reme agnj cagcpgaoe_ an a apicodji ja nes di ajeopnen abe_ 6,0/ EU 'i < 3 hagen: i < 3 aehagen(-Baoa reme cjhkame_ ]t a orj,oadge_ pikadme_ Qop_eio'n o oeno-Gi agg noaodnodcag oenon+ oce ndbidadcaice geqeg ran neo ao k ; /-/4-Pekmeneioaodqe cjmjiag necodjin ja a AQ 08 ijne ai_ ajme]madi-Kdbmaojmt iepmjin eskmenndib EiPF hPL? 'O,P: agpjmenceio di ndop ct]md_dnaodji: ammjrn( jm dhhpijmeacodqe ajm EiPF 'Q& S( ame ncjri-'R& T( ame a_eaceio necodjin ja c ai_ e+ menkecodqegt+ dicp]aoe_ rdoc aiod,EiPF aiod]j_t kmea]njm]e_ rdoc EiPF,G kekod_e-Rce gacf ja ndbiag meqeagn ocao agg EiPF iepmjin ame EiPF,G ai_ ijo EiPF,GG ceggn-Qcage ]amn9 O-P+ 4/ μh: Q-R+ 0// μh: S+ 7/ μh: T+ 1/ μh-Ch]mtjn reme camqenoe_ ao eh]mtjidc _at C03-4 amjh ]gacf A46BJ.5 hdce-Fea_n amjh oce eh]mtjn reme rance_ ocjmjpbcgt di cjg_ /-/0K NBQ+ adse_ di adsaodqe njgpodji Y3% kamaajmhag_ect_e 'ND?(+ /-/0K NBQ+ kF 6-3Z ajm 5-7 c ao 3yA ai_ cmtjkmjoecoe_ di 1/% npcmjne jqemidbco ao 3yA-Rce ajggjrdib _at+ cea_n reme eh]e__e_ di MAR eh]e__dib he_dph 'Rdnnpe,Ref+ Rjmmeice A?+ SQ?(+ amjuei ji _mt dce+ ai_ nojme_ ao ,7/yA piodg necodjidib-Rce eh]mtj cea_n reme cjmjiaggt cmtjnecodjie_ 'Jedca Kdcmjntnoehn+ Ueougam Eemhait( ao 05μh dioemqagn _dmecogt jioj ngd_en ai_ nojme_ ao ,7/yA piodg pne-?_pgo hdce reme aiaenoceodne_ rdoc 4/,0//hb.fb ja feoahdie,FAg ai_ 4,0/hb.fb stgaudie,FAg ai_ omaincam_daggt kemapne_ rdoc 3/hJ ja nagdie+ ajggjre_ ]t 0//hJ ja 3% ND?+ kF 6-3-Bmadin reme cjggecoe_+ kjnoadse_ di oce nahe adsaodqe ajm 1c ao 3yA+ cmtjkmjoecoe_ di 1/% npcmjne jqemidbco-Ch]e__e_ di MAR eh]e__dib he_dph+ amjuei ji _mt dce ai_ nojme_ ao ,7/yA piodg cmtjnecodjidib-?_pgo ]madin reme necodjie_ ao 24μh pndib oce cmtjnoao ai_ nojme_ di aiod,ameeue he_dph ao ,1/yA piodg pne-Ghhpijga]eggdib ran cjhkgeoe_ an ajggjrn9 necodjin reme ocare_ ao PR ]eajme 2 s 4hdi rancen di /-/0K NBQ-Qecodjin reme ocei dicp]aoe_ rdoc kmdhamt aiod]j_t di a njgpodji cjioadidib 0/% ijmhag _jifet nemph ai_ /-2% Rmdoji V0// ajm 2 _atn ao 3yA-2 s 4 hdi rancen di /-/0K NBQ reme ajggjre_ ]t dicp]aodji di akkmjkmdaoegt cjiepbaoe_ necji_amt aiod]j_den 'IOPlS 2( ajm 0c ]eajme dicp]aodji rdoc Fjeccno 090/+///-?aoem 2 s 4 hdi rancen di /-/0K NBQ necodjin reme cjqemngdkke_ pndib Kjrdjg an ai aiod,aa_e hjpiodib he_dphreme j]oadie_ amjh odhe_,kmebiaio aidhagn-Lanag kdon ja C00-4 UR A46BJ.5H hdce reme dnjgaoe_ pi_em anekodc cji_dodjin di Emet&n Bagaice_ Qago Qjgpodji 'Giqdomjbei( eimdcce_ rdoc bgpcjne 'Qdbha,?g_mdcc( ai_ hadioadie_ ao 3yA piodg kgaodib-Cskgaion reme kgace_ jioj bgann cjqemngdkn cjaoe_ rdoc 0/μg ja ccdcfei kganha 'Ajcagdcj Bdjgjbdcagn+ Gic-(-Rcmjh]di '0/μg: Qdbha,?g_mdcc( ran ocei a__e_ oj a_ceme 'ocmjh]di.kganha cgjo( oce eskgaio oj oce cjqemngdk-Cskgaion reme hadioadie_ di _eadie_ nemph,amee he_dph 'QDK( cjioadidib 1-4 hb.hg Dpibdujie 'Qdbha,?g_mdcc( ao 26yA rdoc 4% AM 1 ajm pk oj 2/ _atn di qdomj '_dq( 'Dpencfj % Umat+ 0883(-Dmjh cpgopme _at 2 oj 5+ amenc he_dph cjioadidib agpjmj_ejstpmd_die '7s0/ ,4 K: Qdbha,?g_mdcc( ran kmjqd_e_ oj dicd]do oce kmjgdaemaodji ja _dqd_dib jgaacojmt iepmjin ai_ iji,iepmjiag eskgaio odnnpe-Rce he_dph ran mekgace_ rdoc amenc QDK ordce a reefhdce cammtdib C00-4 eh]mtjn reme aiaenoceodne_+ ai_ oce poemdie cjmin reme beiogt kgace_ jpond_e oce a]_jhdiag caqdot ai_ cjinoaiogt ct_maoe_ rdoc 24yA noemdge nagdie-Sndib a Laijadg ntmdibe ai_ a 24 E? iee_ge aooaccheio 'Ujmg_ Nmecdndji Ginompheion(+ 1μg cjioadidib /-3μb ja ?KFP1 Lepomagdndib ?iod]j_t '?KFP1,L?+ IOPlS 1 ajm meaemeice( ai_ Dgpjmjbjg_™ omacem 0904// 'Qdbha ?g_mdcc+ #28175( _dgpoe_ di nagdie ran dieecoe_ dioma,poemjdi oce jgaacojmt kgacj_e ja oce eh]mtjn-Rce menkecodqe cjiomjgn reme dieecoe_ edocem nagdie 0% BKQM-Rce poemd reme beiogt meopmie_ ai_ oce hjocemn npopme_ ai_ hjidojme_ ajm aer _atn-Ch]mtjn reme cjggecoe_ ao eh]mtjidc _at 03-4 'C03-4( ajm EiPF iepmji lpaiodadcaodji-Dgpjmjbjg_™ ran pne_ di jm_em oj qemdat oce nkecdadcdot ja oce dieecodji ndoen-Rce cjiceiomaodji ja ?KFP1,L? ran _eoemhdie_ ]ane_ ji oce haipaacopmemn mecjhhei_aodjin-Gi jm_em oj qagd_aoe rceocem oce cjiceiomaodji ran ctojojsdc+ jqemagg hjmkcjgjbt ja oce ianag nompcopmen ran esahdie_ ai_ EiPF cegg iph]emn cjpioe_-Qemdag nabdooag necodjin '05μh( amjh C03-4 UR eh]mtjn+ 'i < 3 kem bmjpk( reme kmekame_ an _encmd]e_ a]jqe-Opaiodoaodqe aiagtndn ja EiPF iepmjiag iph]em+ an a apicodji ja gjcaodji+ ran kemajmhe_ jqem ajpm mebdjin 'oce ianag cjhkamoheio+ oce ianag.ajme]madi epicodji+ qeiomag ajme]madi ai_ cjmoes(-Qemdag cjmjiag necodjin '2/μh( ja ?KFP1 *.* 'aehagen+ i < 3: hagen+ i < 2(+ ?KFP1 *., 'aehagen+ i < 3: hagen+ i < 2( ai_ ?KFP1 ,., hjpne ]madin reme pne_ oj cjpio oce ojoag iph]em ja EiPF ceggn ocmjpbcjpo oce eiodme ]madi ai_ cjh]die_ oj bdqe bmjpk heain z QCK-PLaneMSR™ ai_ QpkemQcmdko x GGG meqemne omaincmdkoane reme ocei a__e_ ]eajme dicp]aodib ajm 4/ hdin ao 4/yA ai_ oemhdiaodib oce meacodji ao 74yA ajm 4 hdin-Ddiaggt+ PLane F ran a__e_ ai_ op]en reme dicp]aoe_ ajm 1/ hdin ao 26yA-Ajiceiomaodjin pne_ accjm_dib oj fdo dinompcodjin-Ajiomjgn rdocjpo meqemne omaincmdkoane reme kemajmhe_ oj _ehjinomaoe oce a]neice ja cjioahdiaodib beijhdc BL? Peacodji kmj_pcon reme nojme_ ao ,1/yA piodg pne-;WUcrS -/( DrWUWn oT Gn11 " GI1-1 QSll lWnSa Bjoc Keggji eo ag-'088/( ai_ Pa_jqdcf eo ag-'0880( pne_ oce R,aiodbei ct]md_, beie akkmjacc oj kmj_pce dhhjmoagdue_ JFPF cegg gdien-Keggji eo ag-'088/( cjinompcoe_ a ct]md_ beie rcdcc cjioadie_ a kjmodji ja oce kmjhjoem mebdji ja oce mao JFPF beie-Rcdn omainbeie ran dieecoe_ dioj jie,cegg eh]mtjn rcdcc reme np]nelpeiogt omainkgaioe_ dioj oce poemd ja knep_jkmebiaio hdce-Aeggn amjh oce ophjm ja jie ja ocene hdce reme _dnkemne_ ai_+ ocmjpbc a nemden ja _daaemeiodag kgaodib kmjce_pmen+ reme kpmdade_ oj a cjhjbeiejpn kjkpgaodji-Rcene ER,0 ceggn reme np]cgjie_ ]t nemdag _dgpodji+ oj kmj_pce ER0,6 ceggn-Gi cjiomano oj Keggji+ Pa_jqdcf eo ag-'0880( cjinompcoe_ a ct]md_ beie cjioadidib oce kmjhjoem amjh oce cphai JFPF beie ocao ran ndhdgamgt apne_ oj oce R,aiodbei cj_dib nelpeice-? ophjm rcdcc dhhpijnoadie_ ajm ]joc R,aiodbei ai_ JFPF ran escdne_ amjh jie ja oce D0 kmjbeit 'hage(+ oce ceggn reme _dnkemne_ ai_ kpmdade_+ ai_ a cegg gdie 'EL( ran _eqegjke_-Ddbpme amjh Ueoneg eo ag-+ 0884-

' 6 (' 7 (' 6 (

 676 Mpm pi_emnoai_dib ja oce _eqegjkheio ja oce ceiomag 'ALQ( ai_ kemdkcemag iemqjpn ntnoehn 'NLQ( dn gambegt _emdqe_ amjh rjmf ji ccdcf eh]mtjn 'e-b-nphhamdne_ ]t Ucdogjcf+ 1//3(+ rdoc hjme meceio rjmf jccpmmdib pndib omacdib nop_den di hdce 'Qem]e_udea eo ag-0881(+ rdoc qemt aer nop_den esahdidib cphai odnnpe-Gi a__dodji oj oce ncamcdot ai_ _daadcpgot diqjgqe_ di rjmfdib rdoc cphai eh]mtjidc odnnpe+ a apmocem gdhdoaodji oj jpm pi_emnoai_dib can ]eei oce gdhdoaodjin dicemeio di oce kmjcenn ja oma_dodjiag cdnojgjbt ai_ hdcmjncjke aiagtndn-?gocjpbc ocene kemhdo esceggeio ceggpgam ai_ np]ceggpgam menjgpodji+ oce ocdi necodjidib ja odnnpe iecenndoaoen a gjnn ja 2Bdheindjiag akkmecdaodji ja nompcopmen-Rcdn dn enkecdaggt kmj]gehaodc _pmdib eh]mtjbeiendn+ rcdcc dn a _tiahdc kmjcenn diqjgqdib cjinoaiogt ccaibdib hjmkcjgjbden an odnnpen eskai_ ai_ _daaemeiodaoe-Apmmeiogt njhe 2B akkmecdaodji ja nompcopme cai cjhe amjh oma_dodjiag necodjidib ai_ hdcmjncjke aiagtndn ]t kmjcenndib nemdag 1B necodjin ja odnnpe oj cmeaoe a 2B mei_emdib 'Emdaadid eo ag-+ 0886(-Rcdn heocj_jgjbt can _mar]acfn+ cjreqem+ an do dn odhe kmjcd]dodqe+ melpdmen cameapg agdbiheio ja nemdag necodjin ai_ njhe diajmhaodji hat ]e _enomjte_ ]t oce necodjidib kmjcenn jm _pmdib oce dhhpijga]eggdib+ an odnnpen ]ecjhe iji,pidajmhgt ramke_+ ojmi jm gjno-Qeqemag a_qaicen di hdcmjncjkt npcc an oce _eqegjkheio ja oce cjiajcag 'Kdinft+ 0877( ai_ 1,kcjoji hdcmjncjken 'Beif eo ag-+ 088/( caqe kemhdooe_ aiagtndn ja ndibge kgaien ja a qjgphe ]t hdidhdudib cjiomd]podjin amjh jocem kamon ja oce qjgphe npcc an apojagpjmenceice ai_ htjbgj]di+ caehjbgj]di ai_ hegaidi gdbco a]njmkodji+ ocene ojj+ cjreqem+ ame gdhdoe_ ]t ocedm a]dgdot oj dhabe _eek rdocdi odnnpen+ cpmmeiogt gdhdoe_ oj >0hh-Rcdn _daadcpgot dn capne_ ]t oce dicemeio 'hdgft' akkeamaice ja gambe qjgphen ja odnnpe capne_ ]t gdbco ncaooemdib rdocdi oce odnnpe+ cjhdib an a menpgo ja oce _daaemdib a]njmkodji kmjkemoden ja oce raoem+ kmjoedin ai_ gdkd_n ocao hafe pk ]djgjbdcag odnnpen-Gi jm_em oj accdeqe bjj_ cgamdot ajm dhabdib+ gdbco ehdooe_ amjh oce odnnpe ai_ eioemdib oce _eoecojm ja oce hdcmjncjke ncjpg_ kann di a ndibge pidajmh _dmecodji-Gi gambe qjgphen+ ocdn _jen ijo mea_dgt jccpm an egecomjin amjh ct_mjkcj]dc hjgecpgen hjme mea_dgt a]njm] gdbco+ cjhkame_ oj ct_mjkcdgdc hjgecpgen ai_ nj kmjkabaodji ja gdbco rdocdi oce odnnpe dn ijo cjhjbeijpn-Rce dioemaacen ]eoreei ocene mebdjin+ capndib gdbco oj kmjkabaoe ao _daaemdib nkee_n ai_ aibgen cai ]e mekmeneioe_ an oce meamacodqe di_es ja eacc otke ja hjgecpge 'meqdere_ ]t Pdccam_nji % Jdccohai+ 1/04(-Gi jm_em oj jqemcjhe ocdn kmj]geh ai_ accdeqe bjj_ qdnpagdnaodji _eek rdocdi a gambe qjgphe+ ai elpdgd]maodji ja meamacodqe di_dcen oj me_pce dicjhjbeiedot di gdbco ncaooem ocmjpbcjpo a nahkge dn melpdme_-Rce admno heocj_ oj a__menn ocdn ]t 'jkodcaggt cgeamdib' odnnpen ran kmjkjne_ ai_ _eqegjke_ ]t oce Eemhai aiaojhdno Uemiem Qkagoecjgou: ]ane_ ji oce _ect_maodji ja odnnpen di jm_em oj accdeqe meamacodqe di_es haoccdib 'Qkagoecjgou 0800: 0803(-Kjme meceiogt rdoc oce a_qaicen di gdbco nceeo agpjmenceice hdcmjncjkt 'JQDK(+ a qamdeot ja jkodcag cgeamdib oeccidlpen caqe ]eei _eqegjke_ ocao agg menpgo di odnnpe cgeamdib ]t ndhdgam kmdicdkgen+ _enkdoe oce pi_emgtdib _daaemeicen di ocedm ccehdcag akkmjaccen ';WUcrS -0(-Rce esaco _eoadgn+ a_qaioaben ai_ _dna_qaioaben ja eacc caqe ]eei meceiogt meqdere_ ai_ cjhkame_ rdoc ajcpnen ji odnnpe nkecdadc melpdmeheion '?uamdkjpm eo ag-+ 1/05(+ ocedm ccehdnomt 'Radiafa eo ag-+ 1/05( ai_ ocedm kctndcag kmdicdkgen 'Pdccam_nji % Jdccohai+ 1/04(-Mie ja ocene kmjojcjgn+ 2BGQAM ]ane_ ji oce a]dgdot ja nkecdadc jmbaidc njgqeion oj _ect_maoe+ njgqaoe oce gdkd_n ai_ capne meamacodqe di_es haoccdib agnj capnen pk oj 4/% me_pcodji di ojoag qjgphe ja oce odnnpe 'Becfem eo ag-+ 1/01: Cmoümf eo ag-+ 1/01a+ 1/01](-Rcene kmjkemoden heai do dn d_eaggt npdoe_ oj esahdie oce _eqegjkheio ja neqemag ]j_t ntnoehn _pmdib oce admno omdhenoem ja cphai _eqegjkheio-Rcdn rjmf kmjqd_en cdbc menjgpodji 2B dhaben ja oce _eqegjkdib kemdkcemag iemqjpn+ hpncpgam+ qancpgam+ cam_djkpghjiamt ai_ pmjbeidoag ntnoehn+ cjreqem+ jigt ji oce rjmf _dmecogt megeqaio oj ocdn ocendn dn kmeneioe_ ceme 'aSS 6ppSnRWf ajm apgg kakem(-;WUcrS -0( 8ompOrWaon oT opbWQOl QlSOrWnU bSQVnWqcSa Mkodcag cgeamdib oeccidlpen cai ]mja_gt ]e _dqd_e_ dioj jmbaidc njgqeio ]ane_ '?( ai_ ct_mjkcdgdc ]ane_ 'B(-0(, 9SdSlopmSnb oT bVS VcmOn pSrWpVSrOl nSrdoca agabSm ? kmjojcjg ajm rcjge,hjpio dhhpijnoadidib ai_ 2BGQAM cgeamdib ran pne_ oj aiagtne oce _eqegjkheio ja cphai eh]mtjn 'admno 7 reefn ja benoaodji( ai_ ajeopnen 'amjh 7-4 oj 03 reefn+ nee HSQbWon /(, ajm noabe _eoemhdiaodji ai_ cganndadcaodjin(-Rce _eqegjkheio ja neinjmt asjin ja oce NLQ ran nop_de_ di cphai eh]mtjn ao AQ08 'i < 1(+ AQ10 'i < 0( ai_ AQ12 'i < 2( pndib aiod]j_den abadino oce iepmji,nkecdadc dioemhe_daoe adgaheio kmjoedi kemdkcemdi 'Nmkc(-Gi mj_eion+ Nmkc dn eskmenne_ ]t neinjmt ai_ apojijhdc asjin 'Namtnef eo ag-+ 0877( ai_ di cphai ajeopnen+ Nmkc can kmeqdjpngt ]eei ncjri oj ga]eg ap_dojmt iemqen 'Jjccem eo ag-+ 1/02(-?n kmeqdjpngt mekjmoe_ ajm hdce 'Begge eo ag-+ 1/03: Peidem eo ag-+ 1/03(+ odnnpe,ncmdifabe ran j]nemqe_ '1/,3/%( di agg nahkgen ]po mehadie_ cjhjbeiejpn ocmjpbcjpo oce eh]mtj-Rce ndue me_pcodji aaoem 2BGQAM eia]ge_ dhabdib ja rcjge eh]mtjn pndib JQDK ai_ aggjre_ qdnpagdnaodji ja Nmkc* kemdkcemag iemqen amjh oce ]madinoeh ai_ nkdiag cjm_ oj ocedm _dnoag esomehdoden ';WUcrS -1 6-8(-Rce dhabdib ja eiodme eh]mtjn ga]egge_ ajm Nmkc ';WUcrS -1 6-7( cgeamgt ncjr oce dicmeane di neinjmt diiemqaodji ocao jccpmn ]eoreei 6,7 reefn ja benoaodji-0(-IrOQWnU bVS SmPrgonWQ QrOnWOl nSrdSa (8CI-8CMII)Rce cmaidag iemqen 'AL( ame ocdmoeei kadmn ja iemqen ocao ehembe _dmecogt amjh oce ]madi ai_ kmdhamdgt megat neinjmt ai_ hjojm diajmhaodji oj ai_ amjh oce cea_ ai_ iecf mebdjin 'oce qabpn iemqe+ ALV ]edib ai escekodji(-Amaidag iemqen ame _encmd]e_ an 'hdse_' an ocet hat cammt neinjmt+ hjojm jm neinjmt ai_ hjojm diajmhaodji 'nee akkei_ds ajm a oa]ge ja cmaidag iemqe iahen ai_ apicodjin(-Kjojiepmji cegg ]j_den ja oce ALn ame ajpi_ rdocdi ipcged rdocdi oce ]madinoeh+ rcdge neinjmt iepmji cegg ]j_den ajmh baibgda jpond_e ja oce ]madi di a kaooemi cjhjgjbjpn oj nkdiag iemqen-Csahdiaodji ja oce diaemdjm npmaace ja ai a_pgo ]madi di_dcaoen AL/,GG ehembe amjh oce ajme]madi+ ALGGG ehemben amjh oce hd_]madi ai_ ALGT,VGG agg ehembe amjh oce cdi_]madi-'ajm a meqder ji AL aiaojht ai_ apicodji -Tdgeinft eo ag '1/04(-Rce Agdidcag ?iaojht ja oce Amaidag Lemqen9 Rce Lemqen ja "Mi Mgthkpn Rjremdib Rjk"9 GQBL 867,0,007,381/0,6(-;WUcrS -1( -9 OnOlgaWa oT pSrWpVSrOl nSrdoca agabSm RSdSlopmSnb Wn VcmOn SmPrgoa( ?gg kaiegn ame JQDK dhaben ja njgqeio,cgeame_ eh]mtjn-Qpmaace nca_dib dhabe 'geao( ai_ Nmkc ga]eggdib ja kemdkcemag iemqen 'mdbco( ao EU6-Mqemgat ja oce npmaace nca_dib dhabe 'bmet( ai_ Nmkc ga]eggdib 'bmeei( ao EU7-'8( Fdbc habidadcaodji dhaben ja Nmkc* diiemqaodji ao EU7-Rce hd__ge ai_ mdbco kaiegn ame jqemgatn ja oce npmaace cjiomano dhabe 'bmet( ai_ Nmkc ga]eggdib 'bmeei(-?]]meqdaodjin9 L+ ijnomdgn: K+ hjpoc: T 1 'hasdggamt( ai_ T 2 'hai_d]pgam(+ necji_ ai_ ocdm_ ]maiccen ja oce omdbehdiag iemqe-Qcage ]amn9 0/// µh di 6+ 1/// µh di 7+ 4// µh di 8 Bpmdib eamgt _eqegjkheio ja oce cdi_]madi+ mebdjin ja kmjgdaemaodib iepmjekdocegdph enoa]gdnc _dnodico nebheion fijri an mcjh]jhemen+ rcdcc bdqe mdne oj oce hjojm ipcged ja ALn GT,TGG ai_ TGGG,VGG-AL neinjmt baibgda jmdbdiaoe amjh ecoj_emhag kgacj_en ai_ LA ceggn+ dicgp_dib oce ianag ai_ jodc kgacj_en an regg an ajpm ekd]maiccdag kgacj_en ja ecoj_emhag ocdcfeidib _jmnag oj oce kcamtibeag amccen-Rce ehembeice ja oce LA _emdqe_ baibgda ja oce gambeno ja oce cmaidag iemqen 'ALT( agjib rdoc ALTGG ame admno qdnd]ge ao AQ0/ 'M'Pacdggt % Kuggem+ 1//6(+ rcdgno oce oemhdiagdn 'AL/( dn oce adiag AL cjhkjieio oj ehembe+ admno _eoecoa]ge ao AQ02 'M'Pacdggt % Küggem+ 1//6(-Nmkc ran abadi pne_ an a hamfem ja neinjmt ALn rcdge ccjgdie aceotg omainaemane 'Ac?R( ran pne_ an a hamfem ja eh]mtjidc hjojiepmjin-Ac?R dn a omainaemane eiuthe menkjind]ge ajm oce ntiocendn ja oce iepmjomainhdooem aceotgccjgdie ai_ dn ocpn ajpi_ di ccjgdiembdc hjojiepmjin ja ]joc oce NLQ-?ccjm_dibgt+ di agg eskemdheion 'i < 11( oceme ran ij jqemgak j]nemqe_ ]eoreei Ac?R* ai_ Nmkc* dhhpijmeacodqe asjin+ agocjpbc ocao hjojm iemqe mjjon reme ijo dhhpijmeacodqe ajm Nmkc '_aoa ijo ncjri(+ npbbenon ocao di cphain+ Nmkc dn _daaemeiodaggt eskmenne_ ]eoreei nkdiag cjm_ ai_ cmaidag hjojm asjin-2B qdmopag _dnnecodji ja jmbai diiemqaodji rdoc Ghamdn nebheioaodji kgpbdin ran kemajmhe_ oj omace+ amodadcdaggt cjgjpm ai_ mecjinompco di_dqd_pag iemqe aancdcgen-Rcdn heocj_ ran akkgde_ oj EU6 'Aamiebde noabe 08+ AQ08: i < 1( ai_ EU7 'i < 0: ;WUcrS -2( cmaidag iemqen oj kmjqd_e oce admno meagdnodc di_dcaodji ja ocedm _eqegjkheio ao ocdn odhe-;WUcrS -2( -9 OnOlgaWa oT QrOnWOl nSrdS RSdSlopmSnb Wn VcmOn SmPrgoa( ?gg kaiegn ame JQDK dhaben ja njgqeio,cgeame_ eh]mtjn-Pdbco qder ja oce cea_ ai_ cmaidag iemqen ao EU6 'Nmkc noadidib(-Mi oce mdbco kaieg+ cmaidag iemqen ame nebheioe_ ai_ cdbcgdbcoe_ rdoc nkecdadc knep_j,cjgjpmn-'7( EU6 eh]mtj noadie_ ajm Nmkc-Rce geao kaieg dn a nebheioaodji ja oce ajpm iemqen diiemqaodib oce ojibpe 'mdbco nd_e(-Rce omdbehdiag iemqe 'T2+ hai_d]pgam np]_dqdndji( ai_ oce ccjm_a othkaid ja oce aacdag iemqe 'TGG] jm Umdn]emb iemqe( cjiomd]poe oj oce gdibpag iemqe-Rce orj jocem iemqen ame oce bgjnnjkcamtibeag 'GV( ai_ ctkjbgjnnpn 'VGG(-Rce mdbco kaieg dn a qeiomag qder ja oce ojibpe-'7( Bjmnag qdern ja oce ojibpe di a EU8-4 ajeopn ga]ege_ ajm Nmkc 'geao( ai_ Ac?R 'mdbco(-Qcage ]amn90/// µh di 6+ 4// µh di B 'geao kaieg(+ 2// µh di 7 'mdbco kaieg( ai_ 8-0(. 9SdSlopmSnb oT bVS VcmOn croUSnWbOl agabSm Gi a_pgo hahhagn+ oce pmjbeidoag ntnoeh dn cjhkmdne_ ja oce fd_ietn+ pmdiamt omacon+ bjia_n ai_ mekmj_pcodqe _pcon-Beajme EU6,EU7+ oce cphai bjia_ag md_ben ame pi_daaemeiodaoe_+ ai_ oce

6CC:M 1

 1 j]nemqaodji ha_e amjh ocdn nop_t dn oce _daaemeiodag qancpgamdnaodji ja oce _eqegjkdib Küggemdai _pcon di hagen ai_ aehagen ao EU0/+ rdoc a ojoag gacf ja cakdggamden npmmjpi_dib ocene nompcopmen di hagen-Rcdn ran agnj oce cane di a EU7 hage eh]mtj+ ai abe kmece_dib oce jineo ja Qjs8 eskmenndji -oce admno hamfem ja hage nes _eoemhdiaodji 'Udgcegh eo ag-+ 1//6(-?gocjpbc do can kmeqdjpngt ]eei ncjri ocao di njhe qemoe]maoen+ iahegt mekodgen ai_ ]dm_n 'Mméag eo ag-+ 0887: Uenoemi eo ag-+ 0888(+ ?KF eskmenndji kmece_en eskmenndji ja Qjs8 ai_ cjiomd]poen oj hage nkecdadc qancpgam kaooemidib ja oce bjia_n di mao cpgopmen 'Pjnn eo ag-+ 1//2(-?gocjpbc+ re _d_ ijo j]oadi aehage eh]mtjn tjpibem ocai EU0/-4+ jpm _aoa npbbeno ocao oce mebmenndji ja oce Küggemdai _pcon+ rcdcc noamon amjpi_ EU0/ cjpg_ ]e gdife_ oj jm aacdgdoaoe_ ]t oce gacf ja qancpgamdnaodji ja ocene _pcon di hagen-Bt cjiomano+ oce Ujgaadai _pcon ame qancpgamdne_ di ]joc nesen-Giomdbpdibgt+ rjmf di hdce can meqeage_ a hage nkecdadc qancpgam kaooemidib ja oce bjia_ag qancpgaopme cai ]e di_pce_ di aehagen ]t omeaoheio rdoc ?KF 'Pjnn eo ag-+ 1//2(-Qkecdadcaggt+ oce ceggn ajmhdib oce _e ijqj qennegn reme ajpi_ oj caqe jmdbdiaoe_ di oce henjiekcmjn ai_ hdbmaoe_ oj oce bjia_+ ajmhdib a cjegjhdc qenneg ocao esoei_n ]eieaoc oce cjegjhdc ekdocegdph ja oce bjia_ ocao jigt ajmhn di ijmhaggt qdmdgdne_ hagen ai_ aehagen omeaoe_ rdoc ?KF-Rcdn npkkjmon kmeqdjpn mekjmon ja jqamdai hancpgdidnaodji di ameehamodi caooge 'Hjno eo ag-+ 0861( ai_ di mao bjia_ag cpgopmen es qdqj 'Tdbdem eo ag-+ 0873(-Uceocem ocdn di_pcodji ja hage nkecdadc qancpgamdnaodji dn ompgt a cjinelpeice ja _dmeco ?KF ndbiaggdib dn picgeam cjreqem+ an ndhdgam eaaecon cai ]e mekgdcaoe_ ]t di qdomj cpgopme ja oce henjiekcmjn di oce kmeneice ja ]ea_n cjaoe_ rdoc edocem BKN1 jm BKN3 'Pjnn eo ag-+ 1//2(-Rcene menpgon cdbcgdbco oce apicodjiag me_pi_aict ocao cai esdno ]eoreei heh]emn ja oce REDβndbiaggdib aahdgt+ agocjpbc do ncjpg_ ]e ijoe_ ocao iedocem BKN1 ijm BKN3 ame eskmenne_ di oce bjia_n _pmdib ocdn _eqegjkheioag rdi_jr+ nj ocedm kctndjgjbdcag dhkjmoaice di mebpgaodib hage qancpgam kaooemidib dn lpenodjia]ge-Rcdn _dnoag apne_ kjmodji ja oce Küggemdai _pcon dn _dnodico amjh oce kmjsdhag mebdji ocao eskmennen Nas1 'di_pce_ ]t oce Ujgaadai _pcon(+ rcemean oce apne_ kjmodji dn didodaggt ajmhe_ di Nas1 hpoaio hdce 'Rjmmen eo ag-+ 0884( -di_dcaodib ai apojijht ja ocdn mebdji-Gioemenodibgt+ jpm menpgon npbbeno oce _dnoag apne_ kamo ja oce Küggemdai _pcon _jen ijo neeh oj mebmenn ai_ gdfegt bdqen mdne oj oce kmjnoaodc pomdcge an can ]eei kmeqdjpngt kmjkjne_'Hacj] eo ag-+ 1/01(-?gocjpbc oce kama_dbh jmdbdiaggt enoa]gdnce_ ]t Hjno ja acodqe mebmenndji ja oce Küggemdai _pcon di hagen ai_ oce kanndqe mebmenndji ja oce Ujgaadai _pcon di aehagen , _pe oj a gacf ja ai_mjbei ndbiaggdib oj hadioadi oceh , can npmqdqe_ dioaco ajm jqem caga a ceiopmt+ meceio rjmf 'Xcaj eo ag-+ 1/06( can ]ebpi oj madne dhkjmoaio lpenodjin cjicemidib don cjhkgeoeienn-Xcaj ai_ cjggeabpen ajpi_ ocao oce jmkcai ipcgeam mecekojm AMSN,RD1 'ccdcfei jqag]phdi pknomeah kmjhjojm omaincmdkodji aacojm 1( akkeamn oj kgat ai acodqe mjge di oce mebmenndji ja oce Ujgaadai _pcon+ he_daoe_ ]t DED ndbiagdib-?gocjpbc dioemnes kceijotken di VW aidhagn cai ]e beiemaoe_ ]t beieodc diqagd_aodji ja aacojmn diqjgqe_ ao agg geqegn ja ?KF ndbiaggdib+ oce nkecdadc fijcf_jri ja AMSN,RD1 di oce Ujgaadai _pco heneiccthe 'Uo0 AmePR1* :Ajpkoa1 a.a ( dn oce admno dioemnes hj_eg beiemaoe_ di VV hdce-Rcao oce apocjmn reme a]ge oj escgp_e hancpgdidnaodji ja oce jqamt ai_ oce kceijheia kemndnoe_ di_ekei_eiogt ja ai_mjbei acodqdot madnen dhkjmoaio lpenodjin a]jpo cjr oce _eqegjkheio ja oce aehage beidoag omaco cjpg_ agnj ]e acodqegt mebpgaoe_-3(-GnGH 9SdSlopmSnb Wn HcmOna4 DlR 8onTWrmObWona " CSe InaWUVba Rce EiPF ntnoeh dn oce hanoem mebpgaojm ja mekmj_pcodqe apicodji di qemoe]maoen+ ai_ agoemaodjin di EiPF ndbiaggdib ai_.jm iepmjiag _eqegjkheio dhkadm cphai mekmj_pcodji-Go dn ocemeajme cmdodcag oj apggt pi_emnoai_ oce heccaidnhn mebpgaodib oce jiojbeiendn+ _daaemeiodaodji ai_ kmeiaoag hdbmaodji ja EiPF iepmjin amjh oce ijne oj oce ]madi-Feme re caqe cji_pcoe_ cjhkmeceindqe aiaojhdcag nop_den ja cphai eh]mtjn.ajeopnen+ oj beo ]eooem dindbco dioj oce _eqegjkheio ja EiPF iepmjin _pmdib oce admno omdhenoem ja benoaodji-Rce pikmece_eioe_ pne ja rcjge,hjpio dhhpijga]eggdib ai_ 2BGQAM oeccijgjbt cjpkge_ rdoc JQK oj cammt jpo oce cdbc,menjgpodji qdnpagdnaodji ja hamfemn ajm qamdjpn cegg ai_ ad]me otken di rcjge eh]mtjn.ajeopnen can ge_ oj neqemag ijqeg j]nemqaodjin cjicemidib ocdn ntnoeh ocao cjpg_ ijo caqe ]eei accdeqe_ rdoc cjiqeiodjiag 1B cdnojgjbdcag aiagtndn-Rcene adi_dibn jkei ier aqeipen di oce nop_t ja cphai ]madi cjiiecodqdot pi_em kctndjgjbdcag ai_ kaocjgjbdcag cji_dodjin-Djm dinoaice+ ocdn nop_t pi_emojjf oce admno lpaiodoaodqe aiagtndn ja EiPF iepmjin di cphai ajeopnen-Ue enoa]gdnce_ ocao ai aqemabe ja 0/+/// EiPF iepmjin ame kmj_pce_ di cphain _pmdib _eqegjkheio-Rcene ceggn ame gdfegt oj npmqdqe ocmjpbc a_pgocjj_+ cjind_emdib ocao oce iph]em ai_ aiaojhdcag _dnomd]podji ja iepmjin cjioadidib oce EiPF omaincmdko ame ndhdgam di a_pgo kjno,hjmoeh ]madin 'Paice eo ag-+ 0883(-Gi_ee_+ ocene apocjmn caqe mekjmoe_ ocao ]end_en oce ctkjocagahpn+ a bmeao kmjkjmodji ja EiPF iepmjin di oce a_pgo cphai ]madi ame ncaooeme_ di esomactkjocagahdc mebdjin dicgp_dib oce habijceggpgam ]anag ajme]madi cjhkges+ esoei_e_ ahtb_aga+ qeiomag kaggd_ph+ ai_ kpoahei 'Paice eo ag-+ 0883(-Mpm aiagtndn agnj ncjrn ocao EiPF iepmjin admno akkeam di oce qdcdidot ja oce kmenphkodqe TLM ao AQ 05 'akkmjs-28 _atn ja benoaodji(+ neqemag _atn eamgdem ocai kmeqdjpngt mekjmoe_ 'Qccraiueg,Dpfp_a eo ag-+ 0885(-Rce apocjmn ja ocdn kmeqdjpn rjmf esahdie_ cphai eh]mtjn ao benoaodjiag _atn 'EB( 17+ 21+ 31 ai_ 35+ ai_ j]nemqe_ EiPF ceggn di oce jgaacojmt kdo ai_ oce ajme]madi ao EB 31+ ]po ijo eamgdem 'Qccraiueg,Dpfp_a eo ag-+ 0885(: dioemhe_daoe noaben ]eoreei EB 21 ai_ 31 reme ijo aiagtne_-?o EB 28 'AQ 05( re _eoecoe_ a ojoag ja 4/ EiPF iepmjin di oce eh]mtj an a rcjge+ agg ja rcdcc reme gjcaoe_ rdocdi oce _eqegjkdib ianag mebdji-Rcdn _dnomd]podji kaooemi ai_ gjr cegg iph]em di_dcaoe ocao AQ 05 cjmmenkji_n oj oce ]dmoc_aoe ja ocdn iepmjei_jcmdie cegg kjkpgaodji-Go can ]eei kmeqdjpngt ncjri di jocem nkecden ocao EiPF,eskmenndib iepmjin hdbmaoe dioj oce ]madi agjib ]maiccen ja oce TLL ai_ RL 'Qccraiueg,Dpfp_a % Naaaa+ 0878: Qccraiueg, Dpfp_a eo ag-+ 0878: Umat eo ag-+ 0878(+ ]joc ja rcdcc ehembe amjh oce qjhemjianag ekdocegdph ai_ mpi he_daggt amjh oce jgaacojmt ekdocegdph ojram_n oce _jmnag mebdji ja oce MB-Fjreqem+ ocedm ceiomag eiomt kjdio _daaemn9 oce TLL meaccen oce ?MB+ rcemean oce RL kmjeecon qeiomaggt ai_ _jmnaggt rdocdi oce ajme]madi oj oambeo nekoag+ ctkjocagahdc ai_ gdh]dc amean 'Neamnji+ 0830: Qccraiueg,Dpfp_a % Naaaa+ 0878: Qccraiueg,Dpfp_a % Qdgqemhai+ 087/: Temiet eo ag-+ 1//1: Udmndb,Udecchaii % Mfa+ 1//1: Umat eo ag-+ 0878(+ diqjgqe_ di cjiomjggdib diiaoe ]ecaqdjpmn ai_ iepmjei_jcmdie menkjinen-Rce dnnpe ja rceocem EiPF iepmjin di cphain agnj meacc ocedm oambeo amean pndib ocdn asjiag ncaaajg_ can ]eei pifijri-Sndib rcjge,hjpio dhhpijga]eggdib ai_ 2BGQAM+ re ajpi_ ocao EiPF iepmjin hdbmaoe dioj neqemag ctkjocagahdc ai_ esomactkjocagahdc ]madi mebdjin di odbco annjcdaodji rdoc kemdkcemdi, kjndodqe TLL.RL ad]men-Rcdn j]nemqaodji di_dcaoen ocao oce qjhemjianag ai_ oemhdiag ntnoehn kgat dhkjmoaio mjgen di oce jiojbeiendn ai_ hdbmaodji ja EiPF iepmjin di oce cphai+ ndhdgam oj jocem hahhagn-Rcdn madnen oce kjnnd]dgdot ocao njhe beieodc ajmhn ja cjibeidoag ctkjbjia_jomjkdc ctkjbjia_dnh di cphain+ ccamacoemdne_ ]t EiPF _eadcdeict ai_ oce aadgpme ja kp]emot jineo+ hdbco ]e _pe oj _eaecodqe ceiomag kmjeecodjin ja oce RL+ capndib dinpaadcdeio.a]emmaio EiPF hdbmaodji-Gi abmeeheio rdoc ocdn ctkjocendn+ kmeqdjpn rjmf amjh jpm ga]jmaojmt can ncjri ocao diomacmaidag kmjeecodjin ja oce TLL.RL+ rcdcc eskmenn Lepmjkdgdi,0+ oce mecekojm ajm oce bpd_aice hjgecpge Qehakcjmdi2?+ aadg oj eioem oce ]madi+ dinoea_ accphpgaodib ao oce _jmnag npmaace ja oce cmd]mdajmh kgaoe di hdce gacfdib a apicodjiag nehakcjmdi,]di_dib _jhadi di Lmk0 'Lmk0neha.Qeha hdce( 'Faiccaoe eo ag-+ 1/01(-Ajicjm_aiogt+ _eadcdeio Qehakcjmdi2? ndbiaggdib akkeamn oj cjiomd]poe oj njhe cphai beieodc mekmj_pcodqe _dnjm_emn ccamacoemdue_ ]t _eaecodqe EiPF hdbmaodji+ npcc an Iagghaii ai_ AF?PEC nti_mjhen 'Faiccaoe eo ag-+ 1/01: Qccpgu eo ag-+ 1/03: Wjpib eo ag-+ 1/01(-?ijocem nomdfdib adi_dib dn oce esdnoeice ja ai eqjgpodjiamdgt cjinemqe_ _jmnag hdbmaojmt kaoc rdocdi oce ]madi ajm EiPF iepmjin-? ndhdgam j]nemqaodji ran ha_e di iji,cphai kmdhaoen oreiot teamn abj 'Opai]ecf eo ag-+ 0886(+ ]po ran ijo cjiadmhe_ jm esoei_e_ oj ait jocem nkecden-Gi oce kmeneio nop_t re d_eiodade_ EiPF iepmjin agjib oce orj hdbmaojmt nomeahn ]joc di cphai ai_ hjpne eh]mtjn+ ai_ ]joc nkecden kjnnenne_ pieskecoe_ EiPF iepmjiag kjkpgaodjin di oce iejcjmoes ai_ oce _eqegjkdib kdmdajmh cjmoes+ diqjgqe_ di jgaacodji-?i a__dodjiag ijoerjmoct ai_ kmeqdjpngt pimekjmoe_ j]nemqaodji di ]joc nkecden ran oce kmeneice ja a ndibge,cegg ocdcf mdib amjpi_ eacc MB-Rce ojkjbmakct ja ocene ceggn nomdfdibgt meneh]gen ocao ja a bmjpk ja jgaacojmt bgjhempgd cagge_ oce "iecfgace" bgjhempgd+ rcdcc npmmjpi_ oce cap_ag ei_ ja oce MBn 'Qcdij_a eo ag-+ 0878(-Gioemenodibgt+ oce iecfgace bgjhempgd caqe ]eei dhkgdcaoe_ di _eoecodib kcemjhjien 'Jdi eo ag-+ 1//3: Redccem eo ag-+ 087/(+ ai_ jpm nop_t ncjrn ocao a ndbidadcaio iph]em ja EiPF iepmjin ai_ ad]men ame nodgg kmeneio _pmdib a_pgocjj_ di oce hjpne MB ai_ oce ?MB-Rcdn j]nemqaodji npbbenon ocao oceme hat ]e njhe an,teo pi_eoemhdie_ cjiiecodqe jm apicodjiag gdif ]eoreei oce EiPF iepmjin di ocdn nompcopme ai_ iepmjin diqjgqe_ di jgaacojmt ai_.jm kcemjhjiag _dncmdhdiaodji-? nompcopmag ai_ apicodjiag gdif ]eoreei EiPF iepmjiag jiojbeiendn ai_ kcemjhjie _eoecodji cjpg_ agnj cjhe amjh jpm j]nemqaodjin cjicemidib oce TLM-Gi cphain ai_ jocem hahhagn+ j_jpmn mekmeneio megeqaio ccehjneinjmt cpen di oce enoa]gdncheio ja eamgt dioemacodjin ]eoreei hjocemn ai_ diaaion 'Bpgac eo ag-+ 1/03(+ ai_ neqemag nop_den caqe d_eiodade_ ]ecaqdjpmag menkjinen oj kcemjhjiag cjhkjpi_n 'Bpgac eo ag-+ 1//2(-Fjreqem+ oce dnnpe ja rceocem ocene menkjinen ame he_daoe_ ]t a apicodjiag TLM can ]eei a haooem ja esoeindqe _e]aoe-Feme+ re ajpi_ ocao oce aiaojhdcag ndoe ja kmenphkodqe TLM _daaemeiodaodji _pmdib eamgt eh]mtjidc _eqegjkheio di cphain dn _eadie_+ an di mj_eion+ ]t oce bma_e_ eskmenndji ja oce omaincmdkodji aacojmn ?N,1α ai_ N?V5-Nmeqdjpn nop_den caqe ncjri ocao a TLM dn _dnodibpdnca]ge di a bmeao kmjkjmodji ja a_pgo cphain 'Dmanieggd eo ag-+ 1/00(-Fjreqem+ oce iepmjiag cjiiecodji ]eoreei oce TLM ai_ oce ?MB can mehadie_ egpndqe-Feme+ re ncjr ocao _pmdib cphai ajeoag _eqegjkheio+ oce TLM ai_ oce ?MB ame di_ee_ aiaojhdcaggt cjiiecoe_+ ndice LPN,1, dhhpijmeacodqe qjhemjianag ad]men kmjeeco oj oce _jmnag MB+ an mekjmoe_ di mj_eion 'Agjpodem eo ag-+ 1//1(-Rce TLM agnj cjioadin nomjibgt Id56, ai_ QMV1,kjndodqe kpoaodqe iepmjbeidc kmecpmnjmn+ di abmeeheio rdoc oce dicmeane di qjgphe ja oce cphai ajeoag TLM ekdocegdph rdoc abe ai_ don kemndnoeice ao geano piodg ]dmoc 'Bcaoiabam eo ag-+ 1//0: Qhdoc % Bcaoiabam+ 1///(-Qdice do akkeamn ocao EiPF iepmjin+ jgaacojmt einceaocdib ceggn ai_ jocem iepmjin ]egjibdib oj oce hdbmaojmt hann ehembe amjh oce TLM+ re ctkjocendue ocao ocene _dqd_dib TLM kmecpmnjmn hdbco ]e oce kmjbeidojmn ja jie jm agg ja oce aajmeheiodjie_ cegg otken-Ddiaggt+ oce cjhkpoem,anndnoe_ 2B mecjinompcodji ja odnnpe necodjin dhhpijga]egge_ ajm EiPF can aggjre_ oce beiemaodji ja oce admno 2B aogan ja EiPF cegg ]j_den ai_ ad]men amjh EU 8 ai_ 01 cphai ajeopnen-Rcene hakkdib eskemdheion caqe meqeage_ oce rd_e _dnomd]podji ja EiPF ceggn ai_ oemhdiagn di neqemag esomactkjocagahdc mebdjin-?gojbeocem+ ocene j]nemqaodjin madne oce diomdbpdib kjnnd]dgdot ocao EiPF iepmjin hat agnj hj_pgaoe an,teo pieskgjme_ iji,mekmj_pcodqe apicodjin-Gi_ee_+ oce EiPF iepmjei_jcmdie ntnoeh can ]eei meceiogt kmjkjne_ oj mebpgaoe ntnoehdc abedib 'Xcaib eo ag-+ 1/02(-Rce d_ea ocao opmidib _jri oce ctkjocagahdc megeane ja hj_pgaojmn npcc an EiPF hat accegemaoe abdib dn di gdie rdoc meceio adi_dibn ocao ctkjbjia_ag hdce+ rcdcc cam]jpm a nkjioaiejpn hpoaodji diacodqaodib oce EiPF beie 'Kanji eo ag-+ 0875(+ escd]do _eheioda,gdfe ccaiben _pmdib abdib 'Bmphhji_ eo ag-+ 1/01(-EiPF cjiceiomaodjin di oce ceme]mjnkdiag agpd_ ame kmjkjmodjiag oj ocjne di oce kjmoag ]gjj_ qennegn rcdcc _egdqem oce iepmjcjmhjie oj oce aioemdjm kdopdoamt 'Tai Tpbo eo ag-+ 0874(-Rce ceme]mjnkdiag agpd_ hat ocpn nemqe oj omainhdo ctkjocagahdc EiPF ndbiagn oj EiPF,mecekojm,eskmenndib iepmjiag kjkpgaodjin di oce cdkkjcahkpn ai_.jm jocem ]madi amean diqjgqe_ di cjbidodji 'Emaibem eo ag-+ 1//3: Udgnji eo ag-+ 1//5(-hdbmaodji ja EiPF ceggn ]joc di hdce ai_ cphain 'Aanjid eo ag-+ 1/05: Qccramodib eo ag-+ 1//0: Wjncd_a eo ag-+ 0884(+ npbbenodib ocao oce _eaecon di oce oambeodib ja ocene asjin cjpg_ cjiomd]poe oj oce agoemaodji di oce EiPF hdbmaojmt kmjcenn _eoecoe_ di ocene aidhagn-2B dhabdib ja njgqeio,cgeame_ jmbain '2BGQAM( dn ai jmbaidc njgqeio,]ane_ heocj_ pne_ oj me_pce gdbco ncaooemdib rdocdi nahkgen+ mei_emdib oceh 'jkodcaggt cgeam' ai_ oceme]t aggjrdib gambe qjgphen oj ]e dhabe_ rdocjpo kmdjm _dnnecodji 'Cmopmf eo ag-+ 1/01: 1/02(-Rcdn heocj_ can kmeqdjpngt ]eei cjh]die_ rdoc ai dhhpijga]eggdib kmjojcjg ajggjre_ ]t gdbco,nceeo ganem ncaiidib hdcmjncjkt 'JQK( oj nop_t iepmjiag cjiiecodqdot di hjpne eh]mtjn ai_ kjnoiaoag ]madin 'Begge eo ag-+ 1/03(-Feme+ re pne_ ocdn oeccidlpe oj nop_t oce 2B jmbaidnaodji ja oce EiPF ai_ jgaacojmt ntnoeh _eqegjkheio di rcjge ?KFP1 *.* ai_ ?KFP1 ,., eh]mtjn-Mpm eskemdheion meqeage_ ocao ]joc acpoe iepomagdnaodji ja ?KFP1 jm beieodc diqagd_aodji ja ocdn mecekojm gea_ oj oce nahe kceijotke rdoc a nomjib accphpgaodji ja EiPF iepmjin di oce ianag mebdji ai_ _eaecon di ]joc oce jgaacojmt oambeodib oj oce MBn ai_ di oce diomacmaidag kmjeecodjin ja oce TLL.RL-Rcene _eaecon nomjibgt meneh]ge oce kceijotke kmeqdjpngt _encmd]e_ di kaocjcdnojgjbdcag aiagtnen ja IQ cphai ajeopnen 'Qccraiueg,Dpfp_a eo ag-+ 0885: Resedma eo ag-+ 1/0/(-Lepmjaiaojhdcag aiagtndn ja ?KFP1 ,., a_pgo ]madin ncjre_ a ndbidadcaio 3/% me_pcodji ja oce EiPF cegg kjkpgaodji cjhkame_ oj rdg_,otke ai_ ceoemjutbjpn aidhagn+ npbbenodib ocao oce EiPF cegg hdbmaodji _eaeco j]nemqe_ di ?KFP1,., hjpne eh]mtjn ran ijo cjmmecoe_ _pmdib gaoem _eqegjkheio-Kjmejqem+ oce _ecmeane di oce iph]em ja RF,dhhpijkjndodqe iepmjin di oce jgaacojmt ]pg]n ja ?KFP1 ,., an cjhkame_ oj rdg_,otke aidhagn nomjibgt npbbenon ocao do menpgon amjh _eadcdon ja aaaemeio kmjeecodji amjh MQL _pmdib _eqegjkheio ai_ ocao ocene aidhagn caqe kmj]a]gt jgaacojmt dhkadmheion-Edqei oce di qdqj eaaecon ja ?KFP1 diqagd_aodji ji EiPF iepmjiag hdbmaodji+ re njpbco oj _dnneco rceocem ?KF agoemn EiPF cegg hjodgdot ai_ oj d_eiodat oce ceggpgam heccaidnhn bjqemidib ocdn menkjine-Mpm di qdomj eskemdheion _ehjinomaoe_ ocao ?KF di_pcen dicmeane_ Discussion: Paper 3 15/ ceggpgam hdbmaodji di EL00 ceggn ai_ ocao ocdn eaaeco dn he_daoe_ ]t oce kmeneice ja ]joc ?KFP1 ai_ BKNP0] ai_ np]nelpeio acodqaodji ja oce K?NI kaocrat-Rce IQ,gdfe kceijotke ja ?KFP1 ,., hdce+ kmjhkoe_ pn oj anf rceocem dinpaadcdeio ?KF ndbiaggdib hdbco agnj ]e diqjgqe_ di oce cphai AFF _dnjm_em-Ue kemajmhe_ rcjge,esjhe nelpeicdib di a gambe cjcjmo ja AFF kmj]ai_n 'i < 002( ai_ ocedm aahdgt heh]emn 'rcei aqadga]ge( ajcpndib ji ?KF ai_ don escgpndqe ]di_dib mecekojm+ ?KFP1+ d_eiodatdib neqemag hdnneine hpoaodjin+ agg di oce ceoemjutbjpn noaoe-Rce gjr keieomaice ja hjno AFF annjcdaoe_ beien cjh]die_ rdoc qamda]ge kceijotkdc kmeneioaodji ahjib aaaecoe_ di_dqd_pagn cammtdib oce nahe beieodc _eaeco+ npbbenon ocao AFF dn ijo a nomdcogt hjijbeidc _dnjm_em-Gi_ee_+ kaodeion cam]jpmdib hpoaodjin di orj jm hjme AFF gjcd caqe ]eei kmeqdjpngt _encmd]e_ 'Ndooegjp_ eo ag-+ 1//6: Qtfdjodn eo ag-+ 1/0/(-Qdice ?KF apicodjin an a cjhj_dhem '_d Ageheioe eo ag-+ 1/0/(+ re ctkjocendne_ ocao ?KF qamdaion di oce ceoemjutbjpn noaoe hdbco caqe a kceijotkdc dhkaco ji EiPF _eqegjkheio.apicodji qda a _jhdiaio,iebaodqe dioemacodji ]eoreei a rdg_,otke ai_ qamdaio ?KF kekod_e-Gioemenodibgt+ re ajpi_ ocao oce cji_dodjie_ he_dph amjh AMQ,6 ceggn omainaecoe_ rdoc oce rdg_,otke ?KF cBL? ndbidadcaiogt dicmeane_ EL00 cegg hjodgdot+ rcemean ?KFn cam]jpmdib oce k-Tag01Egt+ k-Egp05/?nk+ k-?nk177Egp+ k-Nmj040Qem+ k-?ga408Tag+ hdnneine hpoaodjin menpgoe_ di a 4/% me_pcodji ja EL00 hdbmaodji cjhkame_ oj oce rdg_,otke ?KF-Rcene menpgon nomjibgt di_dcaoe ocao oce ?KF hpoaodjin d_eiodade_ di AFF caqe a kaocjbeidc eaaeco-Kjmejqem+ ndice EL00 ceggn ei_jbeijpngt eskmenn ?KF+ ocene menpgon agnj npbbeno ocao jigt a kmjkjmodji ja ei_jbeijpn ?KF _dhemn ame a]ge oj accdeqe ndbiaggdib caka]dgdot di qdomj ai_ ocao oce jocem amacodji _dhemduen rdoc oce hpoaio ?KF _emdqdib amjh oce AMQ,6 cji_dodjie_ he_dph+ apmocem np]noaiodaodib oce _jhdiaio,iebaodqe dioemacodji hj_eg ja oce ?KF qamdaion-?KF hpoaodjin aaaecodib EL00 cegg hjodgdot reme ajpi_ di ]joc IQ ai_ iAFF aaaecoe_ di_dqd_pagn-Ue ocpn nkecpgaoe ocao EiPF hdbmaojmt _eaecon hdbco agnj jccpm di njhe ajmhn ja iAFF-Rcdn ctkjocendn cjiomanon oce cpmmeio qder ja AFF kaocjbeiendn+ rceme]t _eaecon di cegg hdbmaodji ja EiPF iepmjin dn ocjpbco oj jccpm jigt di IQ ai_ ijo di iAFF kaodeion 'Bjech eo ag-+ 1/04(-Fjreqem+ cdnojgjbdcag esahdiaodji ja EiPF iepmjin di cphai ajeopnen cammtdib hpoaodjin di iAFF beien can ieqem ]eei kemajmhe_-Ue ]egdeqe ocao oce agoemaodjin ja MB diiemqaodji ai_ ja EiPF hdbmaodji+ ocao ccamacoemdne oce IQ kaocjbeiendn+ hat ijo ]e diesomdca]gt gdife_ eqeion-Gi_ee_+ re meceiogt ncjre_ pndib rcjge,hjpio dhhpijga]eggdib ai_ odnnpe,cgeamdib 'Aanjid eo ag-+ 1/05(+ ocao EiPF iepmjin di cphai ajeopnen hdbmaoe dioj ocedm oambeo ]madi mebdjin di odbco annjcdaodji rdoc qjhemjianag ai_ oemhdiag ad]men jigt-Rcdn di_dcaoen ocao oce qjhemjianag ai_ oemhdiag ntnoehn kgat dhkjmoaio mjgen di oce jiojbeiendn ai_ hdbmaodji ja EiPF iepmjin di cphain ai_ madnen oce diomdbpdib kjnnd]dgdot ocao njhe beieodc ajmhn ja AFF di cphain hdbco ]e _pe oj _eaecodqe ceiomag kmjeecodjin ja oce oemhdiag iemqe+ capndib dinpaadcdeio.a]emmaio EiPF hdbmaodji+ maocem ocai ]edib annjcdaoe_ rdoc _eaecodqe jgaacojmt asji oambeodib-Gi npkkjmo ja ocdn+ ceme re kmeneio eqd_eice ocao ]joc oce oemhdiag iemqe kmjeecodjin an regg an oce hdbmaodji ja EiPF iepmjin reme cdbcgt kemopm]e_ di hjpne eh]mtjn rcei ?KFP1 ndbiaggdib ran kcamhacjgjbdcaggt jm beieodcaggt iepomagdne_-Qdhdgam _eaecon di oce kmjeecodji ja oce qjhemjianag.oemhdiag iemqen ai_ hdbmaodji ja EiPF iepmjin caqe ]eei kmeqdjpngt mekjmoe_ di aidhag hj_egn cam]jpmdib hpoaodjin di fijri IQ, annjcdaoe_ beien+ npcc an Qeha2? 'Aamd]jid eo ag-+ 1/00: Faiccaoe eo ag-+ 1/01: Wjpib eo ag-+ 1/01(-Ucdgno jocem aacojmn 'e-b-Qeha3B( caqe ]eei ncjri oj agoem EiPF hdbmaojmt acodqdot rdoc ij eaaeco ji oce _eqegjkheio ja MQLn 'Edacj]did eo ag-+ 1//7(-Gi nphhamt+ ocdn rjmf kmjqd_en dindbcon dioj oce hjgecpgam ]andn ja ?KF,_ekei_eio ndbiaggdib di oce cjmmeco enoa]gdncheio ja oce EiPF hdbmaojmt kmjcenn-Jacf ja ocdn ndbiaggdib kaocrat dhkadmn oce adiag ndue ja oce EiPF iepmjiag kjkpgaodji di a_pgocjj_ ai_ oce jmbaidnaodji ja oce MB-;WUcrS /2( EropoaSR aSUrSUObWon oT GnGH mWUrOborg RSTSQba PSbeSSn KH OnR n8HH agnRromSa ?goemaodjin ja MB diiemqaodji ai_ ja EiPF hdbmaodji+ ocao ccamacoemdne IQ kaocjbeiendn+ hat ijo ]e diesomdca]gt gdife_ eqeion ]ane_ ji oce _aoa kmeneioe_ di ocdn ocendn-?gocjpbc oce _eqegjkheio ja oce jgaacojmt ai_ EiPF ntnoehn ame diodhaoegt gdife_+ do akkeamn ocao EiPF hdbmaodji di cphain jccpmn agjib oemhdiag ai_ TLL ad]men jigt-Feme re kmeneio eqd_eice ocao ]joc oce oemhdiag iemqe kmjeecodjin an regg an oce hdbmaodji ja EiPF iepmjin reme cdbcgt kemopm]e_ di hjpne eh]mtjn rcei ?KFP1 ndbiaggdib ran kcamhacjgjbdcaggt jm beieodcaggt iepomagdne_ ai_ npkkjmon oce kjnnd]dgdot ocao njhe beieodc ajmhn ja iAFF di cphain hdbco ]e _pe oj _eaecodqe ceiomag kmjeecodjin ja oce oemhdiag iemqe+ capndib dinpaadcdeio.a]emmaio EiPF hdbmaodji+ maocem ocai ]edib annjcdaoe_ rdoc _eaecodqe jgaacojmt asji oambeodib Eeiemaodib a kmecdne ceggpgam ai_ hjgecpgam camojbmakct ja oce cphai eh]mtj dn enneiodag oj pi_emnoai_ oce heccaidnhn ja jmbaijbeiendn di ijmhag ai_ kaocjgjbdcag cji_dodjin-Feme+ re cjh]die_ rcjge,hjpio dhhpijnoadidib+ 2BGQAM cgeamdib ai_ gdbco,nceeo dhabdib oj hafe oce admno noekn ojram_n ]pdg_dib a ocmee,_dheindjiag ceggpgam hak ja cphai _eqegjkheio _pmdib oce admno omdhenoem ja benoaodji-Ue kmjqd_e 2B dhaben ao ai pikmece_eioe_ menjgpodji ja oce neqemag _eqegjkdib ntnoehn dicgp_dib oce kemdkcemag iemqjpn ntnoeh ai_ oce pmjbeidoag ntnoeh-Ue kmeneio eqd_eice ajm a _daaemeiodag qancpgamdnaodji ja hage ai_ aehage beidoag omacon cjicjhdoaio oj nes _eoemhdiaodji-Rcdn rjmf kaqen oce rat ajm a ceggpgam ai_ hjgecpgam meaemeice aogan ja cphai ceggn rcdcc dn cmdodcag oj pi_emnoai_dib cphai _eqegjkheioag _dnjm_emn-?__dodjiaggt+ oce menpgon _encmd]e_ di oce kmeqdjpn ccakoemn cegk oj egpcd_aoe neqemag dhkjmoaio hjmkcjgjbdcag ai_ apicodjiag ankecon ja oce _eqegjkheio ja oce EiPF,0 ntnoeh di ]joc hdce ai_ cphain-Ue kmjqd_e oce admno eqd_eice ja EiPF dhhpijmeacodqdot ao AQ05+ akkmjsdhaoegt 28 _atn ja benoaodji+ cjiadmhdib oce ]dmoc ja ocdn kjkpgaodji jccpmn neqemag _atn eamgdem ocai can kmeqdjpngt ]eei mekjmoe_-Mpm lpaiodadcaodji ja oce ojoag iph]em ja EiPF ceggn kmeneio _pmdib cphai _eqegjkheio dn oce admno ja don fdi_ ai_ npbbenon a makd_ dicmeane di oce ndue ja oce kjkpgaodji jccpmn ]eoreei oce 28 oc ai_ 33 oc _atn ja benoaodji+ mdndib amjh 4/ ceggn oj ai aqemabe ja amjpi_ 7+/// ceggn epno a aer _atn gaoem-Rcdn iph]em dn cdbcgt gdfegt oj ]e ai accpmaoe mekmeneioaodji ja oce ojoag kjkpgaodji an EiPF,0 hPL? can ]eei ncjri oj escd]do a qemt ndhdgam kaooemi ja eskmenndji ai_ di a ndhdgam iph]em di a_pgo kjno,hjmoeh ]madin-Rce cjiadmhaodji ja adi_dibn mekjmoe_ 1/ teamn abj di mcenpn hacalpen ja a _jmnag hdbmaojmt kaocrat+ gea_dib oj esoma,ctkjocagahdc kjkpgaodjin ja EiPF eskmenndib iepmjin kaqen oce rat ajm escdodib ier ncdeiodadc ai_ cgdidcag _dncjqemden ji oce mjge ja EiPF eskmenndji ai_ megeane di cphai mekmj_pcodqe kctndjgjbt+ jgaacojmt ]ecaqdjpm ai_ cjbidodqe kmjcennen-Amaidag iemqen Étude anatomique, moléculaire et génétique de migration des neurones à GnRH chez la souris et l'homme Résumé Chez les mammifères, le contrôle de la reproduction est médié par un réseau hypothalamique qui intègre divers stimuli pour réguler la sécrétion de la Gonadotropin Releasing Hormone (GnRH). Ces neurones à GnRH naissent dans la placode olfactive et migrent vers le cerveau le long des axones vomeronasaux et terminaux au cours du développement embryonnaire. Bien que ce processus a bien été étudié chez les rongeurs, sa caractérisation complète chez l'homme reste inachevée. Il est largement admis que des perturbations dans le développement ou dans la sécrétion de GnRH sont associées chez l'homme à un hypogonadisme hypogonadotrope congénital (CHH), qui est un trouble caractérisé par un retard ou une absence de la puberté conduisant à l'infertilité. Les systèmes GnRH et olfactif ont des liens complexes au cours du développement, le syndrome de Kallmann (KS) représente un trouble qui associe l'hypogonadisme dû à une déficience en GnRH et l'anosmie. Le CHH et le KS sont des troubles oligogéniques, les mutations génétiques sous-jacentes n'expliquent que 50% des cas cliniques. Dans cette étude, nous avons entrepris une caractérisation complète du processus migratoire des neurones à GnRH au cours du premier trimestre de gestation sur une grande série d'embryons et de foetus humains, ce qui nous a permis d'élaborer le premier atlas chronologique et quantitatif de la distribution de GnRH. En effet, l'utilisation d'une nouvelle approche de transparisation des tissus embryologiques humains par de solvants organiques, a permis d'établir pour la première fois, une véritable représentation des neurones dans leur contexte natal in vivo. De plus, les résultats de cette étude ont non seulement révélé que le nombre de neurones GnRH chez l'homme était significativement plus élevé que prévu, mais aussi que ces derniers migrent vers plusieurs régions du cerveau extra-hypothalamique, en plus de l'hypothalamus. Leur présence dans ces régions soulève l'hypothèse qu'ils pourraient exercer des rôles non reproductifs, créant de nouvelles pistes pour la recherche sur les fonctions du système GnRH dans les processus cognitifs, comportementaux et physiologiques. Le second objectif de ce travail a visé à caractériser un nouveau gène candidat impliqué dans le développement du système GnRH: L'hormone Anti-Müllerienne (AMH), connue pour son rôle dans la différenciation de la gonade bipotentielle chez les mâles. Néanmoins, une récente étude menée par notre équipe a mis en évidence son rôle extragonadique sur les neurones à GnRH en période post-natale. Le séquençage complet d'une large cohorte de patients européens a révélé plusieurs nouvelles mutations faux-sens dans le gène de l'AMH chez les patients atteints de CHH et KS, non retrouvés dans la cohorte des témoins. L'évaluation de la pertinence fonctionnelle de ces mutations a ensuite été effectuée par diverses analyses biochimiques in vitro de la bioactivité des mutations, ainsi que par la caractérisation d'une lignée de souris transgénique. Ce qui a entraîné une diminution de la sécrétion de l'AMH et une diminution de la bioactivité de la protéine sécrétée dans les études in vitro; Conduisant à une éventuelle réduction de la capacité migratoire. Cela suggère fortement que ces mutations pourraient avoir un effet pathogène. En outre,nous montrons que le récepteur AMHR2 est exprimé le long des fibres olfactives et par les neurones à GnRH pendant le processus migratoire GnRH. L'analyse pathohistologique des souris Amhr2 -/-a révélé une altération de la migration embryonnaire des neurones à GnRH vers le cerveau antérieur basal, entraînant une réduction significative du nombre total de neurones GnRH dans les cerveaux adultes de ces animaux, conduisant à une fertilité réduite. L'ensemble de ces travaux indiquent que l'insuffisance de signalisation AMH contribuerait à la pathogenèse des troubles de CHH chez l'homme, et met en évidence un nouveau rôle de l'AMH dans développement et la fonction des neurones GnRH.

  43 nCHH probants, qui ont identifié plusieurs mutations hémisomeos hétérozygotes dans les gènes AMH et AMHR2 chez les individus KS et nCHH. La validation biochimique a révélé que plusieurs formes mutées QommWbbSS ajm 3 oc ejdio heeodib ja oce Bmdodnc 'BQL( ai_ Dmeicc 'QLC( Lepmjei_jcmdie Qjcdeoden+ Jdgge+ Dmaice+ 1/04-Ue]hanoem+ kamodcdkaio mebdnomaodjin+ haiabeheio ja a]nomaco ]jjf-

		Apmmdcpgph Tdoae ?]]meqdaodjin Njgtqditgd_eie agpjmd_e HSlSQbSR QonTSrSnQSa proQSSRWnUa NQ? Njgtndagdc acd_ NTBD
	:RcQObWon 9SUrSS yA 2BGQAM kTLM PL? 8orS orUOnWaWnU • ;WSlR oT abcRg • Bebmeen Aegndpn 2,Bdheindjiag dhabdib ja njgqeio cgeame_ jmbain InabWbcbWon Nmenphkodqe TLM Pd]jipcgedc acd_ ?JI ?codqdi gdfe fdiane BOlonS H6+ Naka_afdn E+ Aannaoegga B+ Adhdij G+ ?cdemij H+ Apd V+ Kdhjpid L+ Kenndia ?+ Ndooegjp_ L+ Edacj]did HcpSrdWaor NSOra ?cq ?codqdi mNM?
		Nc-B N-? ijqeg mjge ajm ?iod,Küggemdai cjmhjie di mebpgaodib oce _eqegjkheio ja oce bjia_jomjkdi megeandib cjmhjie Lepmjncdeice Sidqemndoé Jdgge 1+ GLQCPK S0061+ Bm-Najgj Edacj]did 1/03,1/06 ?KF ?iod,Küggemdai cjmhjie ieorjmf Dmaice Njnoem ?KFP1 ?KF mecekojm 1
		Dmeicc Qjcdeot ajm Lepmjncdeice ?KN? α,ahdij,2,ct_mjst,4,heoctg,3,dnjsaujgekmjkdjidc acd_
	•	K-Qc Bjm_eaps+ Dmaice+ Kat 1/06 Lepmjncdeice ?LMT? ?iagtndn ja qamdaice Sidqemndoé Jdgge 1+ GLQCPK S0061+ ?P ?i_mjbei mecekojm Dmaice BOlonS H6+ Naka_afdn E+ Aannaoegga B+ Adhdij G+ ?cdemij H+ Apd V+ Kdhjpid L+ Kenndia ?+ Ndooegjp_ L+ Edacj]did Bm-Najgj Edacj]did 1/02,1/03 ß2EiR0 ß0+2,L aceotgbgpcjnahditgomainaemane,0
		N-? ijqeg mjge ajm ?iod,Küggemdai cjmhjie di mebpgaodib oce _eqegjkheio ja oce bjia_jomjkdi megeandib cjmhjie
		B-Qc ieorjmf	?iaojhdcag Qcdeice	Sidqemndot ja Bmdnojg+ SI	Bm-Bjhdibj Rjmojiene+	1//8,1/01
		Njnoem	% Nctndjgjbt		Bm-Baqd_ Baoen
		Qjcdeot ajm Lepmjncdeice
		Qai Bdebj+ SQ?+ Ljqeh]em 1/05
		EoaWbWon
			COmS OnR IgpS	InabWbcbWon OnR loQObWon	NSOra
		Bjcojmag Deggjrncdk	Sidqemndoé Jdgge 1+ GLQCPK S0061+ Dmaice	1/03,1/06
		Kanoem Deggjrncdk	Sidqemndoé Jdgge 1+ GLQCPK S0061+ Dmaice	1/02,1/03
		Peneamcc Ajiomaco	Sidqemndot ja Bmdnojg+ ?iaojht Beko+ SI	1/01,1/01
		EcPlWQObWona
		ieorjmf
		Qcdeiodadc heeodib ja oce Cpmjkeai EiPF ieorjmf Njnoem _jd90/-0//1.cie-13146 Nmaoj+ Goagt+ Kamcc 1/04		1/06-
	• •	Begge K+ Ej_eamjt B+ Ajpgt E+ BOlonS H6+ Ajggdem D+ Edacj]did N+ Acé_joag ?-Rmd_dheindjiag Tdnpagduaodji ai_ BOlonS H6+ Naka_afdn E+ Aannaoegga B+ Adhdij G+ ?cdemij H+ Apd V+ Kdhjpid L+ Kenndia ?+ Ndooegjp_ L+ Edacj]did ?iagtndn ja Camgt Fphai Beqegjkheio-Aegg-1/06-_jd90/-0/05.e-cegg-1/06-/2-//7 N-? ijqeg mjge ajm ?iod,Küggemdai cjmhjie di mebpgaodib oce _eqegjkheio ja oce bjia_jomjkdi megeandib cjmhjie
	•	ieorjmf Aanjid D)+ BOlonS H6)+ Begge K+ Jpuuaod D+ Ajggdem D+ ?ggeo A+ Fma]jqnuft C+ Pandfa Q+ Nmeqjo T+ Acé_joag T+ Cpmjkeai Ajiaemeice ja Agdidcag Ci_jcmdijgjbt Edacj]did N-Beqegjkheio ja Rce Lepmjin Ajiomjggdib Demodgdot di Fphain9 Ler Gindbcon amjh 2B Ghabdib % Njnoem )eon PSab poabSr Rmainkameio Deoag Bmadin-Beqegjkheio-1/05 0329 2858,2870: _jd9 0/-0131._eq-028333 Pjpei+ Dmaice+ ?pbpno 1/03

•

BOlonS H6+ Naka_afdn E+ Aannaoegga B+ Adhdij G+ ?cdemij H+ Apd V+ Kdhjpid L+ Kenndia ?+ Ndooegjp_ L+ Edacj]did

N-Beaecodqe ?iod,Küggemdai Fjmhjie

Qdbiaggdib ?goemn oce Beqegjkheio ja oce EiPF.Mgaacojmt ntnoehn % Ajiomd]poen oj Ajibeidoag Ftkjbjia_dc Ftkjbjia_dnh-Gi kmekamaodji • Acaccgafd I+ BOlonS H6+ Opaggn,Ameefhjme C+ Fma]jqnuft C+ Kpiu]emb F+ Edacj]did N+ ?ibj D+ Nmeqjo T-Nceijotkdib ja iLMQ Lepmjin di oce Njnoiaoag ai_ ?_pgo Dehage Kjpne Ftkjocagahpn-H Ajhk Lepmjg+ • Namfanc H+ Kenndia ?+ Jaibgeo D+ Adhdij G+ Jjtein ?+ Kaupm B+ Eaggeo Q+ Baggai_ C& BOlonS H6+ Nmagjib DN+ Aabijid E+ Qcceggdij P+ Be Kamccdn Q+ Kauujie K+ Nanoemfahk HP+ Rahabijie J+ Nmeqjo T+ Edacj]did N-Qehakcjmdi6? Pebpgaoen Lepmjbgdag Nganodcdot ao oce ?_pgo Ftkjocagahdc Ke_dai Chdieice-Laopme Ajhhpidcaodjin-1/04+ 595274 _jd90/-0/27.icjhhn6274-• BOlonS H6+ Naka_afdn E+ Aannaoegga B+ Adhdij G+ ?cdemij H+ Apd V+ Kdhjpid L+ Kenndia ?+ Ndooegjp_ L+ Edacj]did N-? ijqeg mjge ajm ?iod,Küggemdai cjmhjie di mebpgaodib oce _eqegjkheio ja oce bjia_jomjkdi megeandib cjmhjie ieorjmf Qcdeiodadc heeodib ja oce Cpmjkeai EiPF ieorjmf Njnoem Bp_akeno+ Fpibamt+ Kamcc 1/05 • BOlonS H6+ Naka_afdn E+ Aannaoegga B+ Adhdij G+ ?cdemij H+ Apd V+ Kdhjpid L+ Kenndia ?+ Ndooegjp_ L+ Edacj]did N-? ijqeg mjge ajm ?iod,Küggemdai cjmhjie di mebpgaodib oce _eqegjkheio ja oce bjia_jomjkdi megeandib cjmhjie ieorjmf Hjpmiée ?i_me Tap]emo Njnoem )eon PSab caS oT WmOUWnU Jdgge+ Dmaice+ Qekoeh]em 1/04 • BOlonS H6+ Naka_afdn E+ Aannaoegga B+ Adhdij G+ ?cdemij H+ Apd V+ Kdhjpid L+ Kenndia ?+ Ndooegjp_ L+ Edacj]did N-? ijqeg mjge ajm ?iod,Küggemdai cjmhjie di mebpgaodib oce _eqegjkheio ja oce bjia_jomjkdi megeandib cjmhjie

8H6EI:G ,

	Ejia_jomjkdi,Pegeandib Fjmhjie Lepmjin9
	Beqegjkheio ai_ Pebpgaodji

,(1 IVS GnGH HgabSm

	Rce iepmjin ocao necmeoe bjia_jomjkdi,megeandib cjmhjie 'EiPF+ agnj fijri an JPD+
	JFPF( caqe ]eei lpaiodoaodqegt annenne_ ]t hait ga]jmaojmden ai_ oce iph]em ja EiPF
	iepmjin di oce ]madin ja hahhagdai nkecden dn enodhaoe_ ao maibdib amjh 7// ceggn di oce eiodme
	]madi di a_pgo mj_eion oj 1+/// iepmjin di oce ctkjocagahpn ja a_pgo cphai ai_ iji,cphai
	kmdhaoen 'Amjrget eo ag-+ 1//7: Idib ai_ ?iocjit+ 0873: Jaodhem eo ag-+ 1///: Qdgqemhai eo ag-+
	0871: Rj]eo eo ag-+ 1//0(-Go dn rjmoc ijodib ocao oce iph]em ja EiPF iepmjin di hdce dn cdbcem
	_pmdib eh]mtjidc _eqegjkheio '0+///,0+1// iepmjin( ai_ dn aerem di a_pgocjj_ 'Kenndia eo
	ag-+ 1/00: Namfanc eo ag-+ 1/01( agocjpbc oce meanji ajm ocdn kjnoiaoag me_pcodji dn cpmmeiogt
	pifijri-EiPF cegg ]j_den ame kme_jhdiaiogt ajpi_ ncaooeme_ di a ]dgaoemag cjiodipph
	ocmjpbcjpo oce _dabjiag ]ai_ ja Bmjca+ rceme ocet cai ]e ajpi_ di oce nekoph+ jmbaiph
	qancpgjnph gahdiae oemhdiagdn 'MTJR(+ kme,jkodc mebdji 'NM?( ai_ he_dj]anag ctkjocagahpn
	';WUcrS 2(-Gi oce nceek+ mao ai_ hjpne+ oce qano haejmdot ja EiPF njhaoa ame gjcaoe_ di ai_
	amjpi_ oce mjnomag kme,jkodc amea 'mNM?(-Gi cjiomano+ a hjme cjhjbeiejpn _dnomd]podji ja
	EiPF cegg ]j_den dn ajpi_ di bpdiea kdbn+ kmdhaoen ai_ cphain 'Bammt 0868: Ejg_nhdoc eo ag-+
	088/: Idib % ?iocjit+ 0873: Imet % Qdgqemhai+ 0867: Qdgqemhai eo ag-+ 0871(-Gi kmdhaoen
	oceme agnj esdnon a

_dnodico kjkpgaodji ja EiPF iepmjin ocao mend_e di oce diapi_d]pgam ipcgepn 'fijri an oce amcpaoe ipcgepn di jocem nkecden(-Rcene ncaooeme_ iepmjin ]t _eadidodji ame ceoemjbeiejpn+ rdoc jigt a kmjkjmodji ]egdeqe_ oj ajmh a _daapne iepmag ieorjmf ocao apicodjin

	The GnRH system
	'EiPF2( ai_ oj oce hd_]madi 'EiPF1(-EiPF2 iepmjin ja oce RL caqe ]eei ncjri oj
	kjnnenn a iepmjhj_pgaojmt mjge di oce ajme]madi ai_ jgaacojmt ekdocegdph '?]e ai_ Mfa+ 1//1:
	Cdnocei eo ag-+ 1///(+ ai_ agnj aco an hj_pgaojmn ja jgaacojmt he_daoe_ ]ecaqdjpmn 'Udmndb,
	Udecchaii eo ag-+ 1//1(-Qdhdgamgt+ oce EiPF1 ceggn ja oce hd_]madi agnj akkeam oj hj_pgaoe
	nespag ]ecaqdjpmn 'Rehkge eo ag-+ 1//2(-?gg oeomakj_n esahdie_ kjnnenn ao geano orj ajmhn ja
	EiPF+ rdoc EiPF0 kgatdib ai ei_jcmdie mjge di hjno nkecden ai_ jocem ajmhn mebpgaodib
	mekmj_pcodqe ]ecaqdjpmn: an agocjpbc ]joc EiPF0 ai_ EiPF1 'cphai ccmjhjnjhe 1/( caqe
	]eei ajpi_ di oce kdopdoamt+ jigt EiPF0 dn ocjpbco oj egdcdo oce necmeodji ja bjia_jomjkdin
	'Ij]atancd eo ag-+ 0883: Kjioaiem eo ag-+ 1//0(-Dmjh ocdn kjdio+ meaemeicen oj EiPF rdgg meaem
	njgegt oj EiPF0 pigenn jocemrdne noaoe_-
	cj,jm_diaoegt an a EiPF kpgne beiemaojm 'Iij]dg+ 1/04(-
	?gocjpbc jmdbdiaggt iahe_ ajm don mjge di mebpgaodib oce FNE asdn+ orj megaoe_ EiPF beien
	caqe ]eei d_eiodade_ di qemoe]maoen+ admno amjh ccdcfein 'Kdtahjoj eo ag-+ 0873( ai_ ocei amjh
	naghji 'Qcemrjj_ eo ag-+ 0872(-Cacc ajmh ja EiPF dn a _ecakekod_e+ ncjrdib cjinemqaodji ao
	kmjoedi mend_pen 0+ 3+ 8 ai_ 0/-?gocjpbc oce beien ai_ ahdij acd_ nelpeicen ja ocene hpgodkge
	EiPF kekod_en dn cjhjgjbjpn 'Demiag_ % Ucdoe+ 0888(+ ocet ame eicj_e_ ]t _daaemeio beien
	ai_ eacc EiPF kekod_e can don jri _dnodico kmjhjojm nelpeice 'Demiag_ % Ucdoe+ 0888(-Rcene
	a__dodjiag ajmhn ja EiPF ame cganndcaggt gjcagdne_ oj oce iemqpn oemhdiagdn 'RL( ja oce ajme]madi
	4/

;WUcrS 2( 9WabrWPcbWon oT GnGH nScrona Wn bVS ORclb mocaS PrOWn(

	Pekmeneioaodqe dhaben ja EiPF dhhpijnoadidib di oce a_pgo hjpne+ aclpdme_ rdoc
	gdbco nceeo dhabdib-EiPF iepmjin ame noadie_ di rcdoe+ rdoc npmaace hj_eggdib ja
	oce qeiomdcpgam ntnoeh 'TGG9 gaoemag qeiomdcge( di bmet-Bjoojh kaieg9 EiPF iepmjin
	']gacf _jon( di oce nabdooag 'ojk( ai_ cjmjiag ']joojh( kgaien-Lepmjin ame ajpi_
	ncaooeme_ di a ]dgaoemag cjiodipph amjh oce jgaacojmt ]pg] oj oce ctkjocagahpn
	ajmhdib ai 'diqemoe_ W' ncake rcei qdere_ cjmjiaggt-Rce ndoe ja EiPF kmjeecodjin+
	oce he_dai ehdieice dn di_dcaoe_ di me_-?]]meqdaodjin9 2T9 2 m_ qeiomdcge: ?A9
	aioemdjm cjhhdnnpme: ?F?9 aioemdjm ctkjocagahdc amea: KQ9 he_dag nekoph: MB9
	jgaacojmt ]pg]: AB9 ceme]eggph: MA9 jkodc ccdanh: AL GG9 jkodc iemqe: MTJR9
	jmbaiph qancpgjnph ja oce gahdia oemhdiagdn: mNM?9 mjnomag kme,jkodc amea:
	TBBB9 qeiomag _dabjiag ]ai_ ja Bmjca-Ghhpijnoadidib ]t Kagjie Q-Bjoojh
	nccehaodc oafei amjh Fem]dnji ?+ ccakoem 00+ Iij]dg'n kctndjgjbt ja mekmj_pcodji

,(, GnGH VgpobVOlOmWQ nSbeorY

	EiPF iepmji hjmkcjgjbt dn neehdibgt pidlpe ahjibno agg oce iepmjin di oce hahhagdai ALQ
	ai_ hat cegk oj eskgadi cjr npcc a kpgne beiemaojm cjpg_ ]e eaaecoe_-Rcet akkeam oj kjnnenn
	?gocjpbc oceme esdno nkecden _daaemeicen di oce aiaojhdcag gjcaodjin ja EiPF iepmjin+ agg orj gjib _ei_mdoen+ rdoc edocem jie jm ]joc kmjeecodib oj oce he_dai ehdieice 'Fem_e eo ag-+
	hahhagn ocpn aam nop_de_ beiemaoe kpgnen ja JF necmeodji+ rcdcc cjmmegaoe rdoc kpgnaodge EiPF 1/02: Fem_e % Fem]dnji+ 1/04(: rdoc ]joc kmjeecodjin mecedqdib ntiakodc dikpon ai_ a]ge oj
	megeane ao oce he_dai ehdieice-Rce omainkgaioaodji ja EiPF iepmjin dioj oce qeiomdcpgam kmjkabaoe acodji kjoeiodagn ojram_n ocedm iepmjnecmeojmt oemhdiagn 'Aahk]egg eo ag-+ 1//4:
	ntnoeh ja oce aajmeheiodjie_ Fkb hjpne di_dcaoe ocao an aer an 1/ EiPF iepmjin ame caka]ge Fem_e % Fem]dnji+ 1/04(-Rcene kmjeecodjin agnj ajmh a ieorjmf+ ]ecjhdib dioemrjqei ai_
	ja beiemaodib kpgnaodge JF necmeodji 'Ijfjmdn eo ag-+ 0877(-Qdhdgamgt+ oce hagen ja a hjpne gdie eqei ncamdib ntiakodc dikpon 'Aahk]egg eo ag-+ 1//8(-?_hdidnomaodji ja iepmjomainhdooem
	ocao kjnnennen jigt 7/ EiPF iepmjin+ reme a]ge oj aaocem jaankmdib 'Fem]dnji eo ag-+ 1//7( -mecekojm aioabjidnon dn caka]ge ja a]jgdncdib EiPF necmeodji 'Ijm_ji eo ag-+ 0883(+ npbbenodib
	pi_emncjmdib oce api_aheioag dhkjmoaice ja EiPF megeane rcdge agnj gei_dib dindbco oj oce ocao ai esoemiag kpgne beiemaojm hat jigt iee_ oj aco ji EiPF _ei_mdodc.asjiag kmjeecodjin
	ceoemjbeiejpn iaopme ja oce EiPF kjkpgaodji-an ocet cjiqembe ojbeocem oj diiemqaoe oce he_dai ehdieice-Gi_ee_+ do ijr akkeamn gdfegt ocao
	Bpmdib mekmj_pcodqe gdae+ jqamdai 'jenomjpn( ctcgdib _ekei_n ji oce hadioeiaice ja EiPF oce amcpaoe kjkpgaodji ja Idnnkekodi+ iepmjfdidiB ai_ _tijmkcdi eskmenndib iepmjin 'ILBt
	megeane rdocdi a iammjr maibe ja kpgne amelpeict ai_ ahkgdop_e 'C]gdib+ 1//4(-Rce dioemqagn iepmjin( dn gdfegt oj kgat a api_aheioag mjge di beiemaodib kpgnen ja EiPF megeane 'Laqammj eo
	]eoreei EiPF kpgnen di qdqj maibe amjh 3/,5/ hdipoen di oce bjia_ecojhdne_ hjifet ag-+ 1//8(-
	'Remanara 0874(+ nceek 'Aamaot eo ag-+ 0878( ai_ mao 'Jeqdie % Bpaat+ 0877(+ rdoc gjibem Ma cjpmne+ rcdgno oce mebpgaodji ja EiPF kpgnaodgdot dn dhkjmoaio oj einpmdib cjiodipe_
	dioemqagn mekjmoe_ di dioaco aidhagn 'Cqain eo ag-+ 0884: Namf % Pahdmeu+ 0878(-?__dodjiaggt+ mekmj_pcodqe cjhkeoeice+ oce kctndjgjbdcag mebpgaodji ja EiPF necmeodji dn aam hjme cjhkges
	ccaiben di ctkjocagahdc EiPF eskmenndji ai_ necmeodji caqe ]eei dhkgdcaoe_ di oce omaindodji ocai ]edib mebpgaoe_ ]t fdnnkekodi agjie-Djm dinoaice+ oce ieorjmf admno ]ecjhen acodqe _pmdib
	ocmjpbc heijkapne 'Udne eo ag-+ 0885: Wdi eo ag-+ 1//5(+ apmocem cdbcgdbcodib oce dhkjmoaice ja hd_ benoaodji di cphain 'Ageheion eo ag-+ 0865: Iakgai eo ag-+ 0865( ai_ oceme esdnon ai a]mpko+
	oce odbco mebpgaodji ja don eskmenndji-0,01
	Rce mebpgaodji ja kpgnaodge EiPF necmeodji can ]eei rd_egt nop_de_+ an cjr npcc a _daapnegt
	nkmea_ kjkpgaodji cjpg_ cjjm_diaoe ocedm admdib oj beiemaoe a nticcmjijpn kpgne dn ijo
	dhhe_daoegt eqd_eio-Fjreqem+ cganndcag omacdib nop_den caqe ncjri ocao di ]joc oce mj_eio ai_
	kmdhaoe ]madi jigt 4/,6/% ja EiPF iepmjin ame ctkjkctndjomjkdc: npbbenodib ijo agg EiPF
	iepmjin ame diqjgqe_ di kpgnaodge megeane ai_ jigt a np]neo ncjpg_ ]e melpdme_ oj cjjm_diaoegt
	adme 'Ejg_nhdoc eo ag-+ 088/: Qdgqemhai eo ag-+ 0876(-Rce d_ea ja ai 'dioemiag' kpgne beiemaojm
	'ocao dn+ a kmjkemot diomdindc oj EiPF iepmjin ocao rjpg_ aggjr oceh oj adme di nticcmjit(+ dn
	cpmmeiogt aaggdib jpo ja aaqjpm+ meceiogt ]edib npkkgaioe_ rdoc ai 'esomdindc hj_eg' ja kpgne
	beiemaodji 'meqdere_ ]t Fem]dnji 1/05(-

cjpm npmbe di JF necmeodji ncjmogt ajggjrdib ]dmoc di ]joc hage mj_eion ai_ kmdhaoen 'Ajm]dem eo ag-+ 0867: Ajm]dem eo ag-+ 088/: _e Xebcem eo ag-+ 0881(-? apmocem omaindeio acodqaodji jccpmn ahjibno cphai diaaion ]ebdiidib ao 0,1 kjnoiaoag reefn+ ai_ kemndnon ajm neqemag

,(-GnGH l ;rom USnS bo probSWn

	Rce EiPF0 beie dn gjcaoe_ ji cphai ccmjhjnjhe 7k10-1 ai_ ccmjhjnjhe 03 di hdce-Rce
	EiPF PL? kmdhamt omaincmdko cjhkmdnen ajpm esjin ai_ ocmee diomjin-Csji 1 eicj_en oce
	EiPF _ecakekod_e+ oce eiuthaodc ahd_aodji ai_ kmecpmnjm kmjcenndib ndoe ai_ oce admno 00
	ahdij acd_n ja E?N0 'nee ]egjr(-Csjin 2 ai_ 3 eicj_e oce mehadidib ahdij acd_n ja E?N0
	ai_ oce 2' piomaingaoe_ mebdji 'Qeghaijaa eo ag-+ 0880(-Nmjcenndib+ ai_ mehjqag ja diomjin ran
	ajpi_ oj ]e gambegt cjinemqe_ ]eoreei nkecden ai_ dn gambegt jpond_e ja oce ncjke ja ocdn ocendn
	'meqdere_ ]t Ejme % Pj]emon+ 0886(-
	EiPF0 dn ntiocendne_ an kamo ja a kmecpmnjm kmjoedi 'kmekmj,EiPF( ja 81 ahdij acd_n-Rcdn
	dicgp_en oce L,oemhdipn cjhkjne_ ja 12 ahdij acd_n+ rcdcc cjioadin oce kmj,EiPF+ ajggjre_
	]t a A,oemhdipn ja 58 ahdij acd_n ocao rdgg bdqe mdne oj E?N0 'EiPF0 annjcdaoe_ kekod_e(+ a
	45,ahdij acd_ kekod_e ocao can ]eei npbbenoe_ oj kamodcdkaoe di oce mebpgaodji ja ]joc kmjgacodi
	ai_ bjia_jomjkdi necmeodji '?_eghai eo ag-+ 0875: Qee]pmb % ?_eghai+ 0873(-Fphai ai_ mao
	E?N0 ncame akkmjsdhaoegt 6/% nelpeice cjhjgjbt '?_eghai eo ag-+ 0875(+ rdoc oce haejmdot
	ja qamdaodji jccpmmdib di oce L,oemhdiag mebdji ja oce kekod_e-Ghhpijctojccehdcag noadidib
	ncjre_ ocao E?N0 cj,gjcagdnen rdoc EiPF cegg ]j_den ai_ ad]men di oce haopme mao 'Ncdggdkn eo
	ag-+ 0874(+ ajeoag mcenpn hacalpe 'Qjib eo ag-+ 0876(+ epqeidge ]a]jjin 'Qjib eo ag-+ 0876( ai_
	cphai ctkjocagahpn 'Qfmakdon eo ag-+ 1/04(-Gon kmeneice di _eine,cjme qendcgen ja oemhdiag
	qamdcjndoden rdocdi oce he_dai ehdieice 'Ncdggdkn eo ag-+ 0874(+ eqeiopaggt ge_ oj don _eoecodji di
	oce kjmoag cdmcpgaodji di jqamdecojhdne_ eren+ rdoc don geqegn cdbcgt cjmmegaoe_ rdoc EiPF geqegn
	'Agamfe eo ag-+ 0876( npkkjmodib ocdn ijodji-Peceiogt a E?N0 aiod]j_t ocao nkecdadcaggt
	mecjbidnen oce cphai ajmh ja E?N0 'cE?N0( can ]eei _eqegjke_ 'Qfmakdon eo ag-+ 1/04(+
	aggjrdib oce nomdco d_eiodadcaodji ja EiPF0 eskmenndib iepmjin di cphain-

;WUcrS 11( 7WoagnbVSaWa oT GnGH OnR G6E( 'BL

  ?( Rce nompcopme ja oce cphai+ mao ai_ hjpne EiPF beie rdoc oce 4' mebpgaojmt nelpeice ai_ nkecdadc mebdjin ja fijri apicodji cdbcgdbcoe_-'PL?(

	Rce mebpgaodji ja ]djgjbdcaggt aqadga]ge EiPF dn cjiomjgge_ ao a hpgodop_e ja ]dj,ntioceodc
	geqegn-EiPF beie eskmenndji dn _eoemhdie_ ]t oce maoe ja omaincmdkodji ja kmj,EiPF+
	kjgta_eitgaodji ai_ cakkdib ja oce PL?+ kmjcenndib ja oce EiPF kmdhamt omaincmdko oj ajmh
	oce haopme hPL? ai_ omainkjmo ja oce hPL? amjh oce ipcgepn oj oce ctojnjg-Leso+ hPL?
	geqegn ame _eoemhdie_ ]t oce opmijqem ja oce hPL?+ rcdge oce maoe ja oce omaingaodji ja oce
	hPL? dioj oce kmj,EiPF kekod_e _eoemhdien oce ahjpio aqadga]ge oj ]e kmjcenne_ dioj oce
	haopme ajmh ja EiPF ocao rdgg ]e kacfabe_ dioj gambe _eine cjme qendcgen oj ]e necmeoe_ 'Idib
	% ?iocjit+ 0872: Paibamaep eo ag-+ 0880(-Rcpn+ EiPF ]djntiocendn dn mebpgaoe_ ao hait geqegn
	'meqdere_ ]t Ejme % Pj]emon+ 0886(-Qop_den caqe ncjri ocao di mj_eion+ EiPF iepmjin
	kjnnenn a gambe+ noea_t noaoe kjjg ja EiPF hPL? ocao akkeamn oj apicodji an a ctojkganhdc
	menemqe-Rcdn accphpgaodji _pe oj gacf ja dhhe_daoe kmjcenndib dn cjhkjpi_e_ an EiPF
	hPL? caga,gdae 'o 0.1 ( dn 11,2/c pi_em ]anag cji_dodjin 'Bmp_em % Uedmhai+ 0883: Wej eo ag-+
	0885(-Rcdn menemqe hat ]e dhkjmoaio ajm makd_ beiemaodji ja oce kekod_e di jm_em oj mekgeidnc
	kekod_e geqegn di aiodcdkaodji ja oce kme,jqpgaojmt npmbe 'Uaib eo ag-+ 0884(+ agocjpbc ocdn
	eqd_eice dn aam amjh cjicgpndqe-Gi_ee_+ do can ]eei mekeaoe_gt npbbenoe_ ocao EiPF ]djntiocendn
	ai_ necmeodji ame ijo odbcogt gdife_-Djm dinoaice+ di qdomj omeaoheio ja dhhjmoagdne_ EiPF cegg
	gdien rdoc oce bgpoahaoe aiagjbpe L,heoctg,9&A,ankamoaoe 'LKB?(+ capnen makd_ dicmeanen di
	EiPF hPL? geqegn di oce a]neice ja ccaiben di oce EiPF kmdhamt omaincmdko geqegn -
	npkkjmodib a gambegt kjno,omaincmdkodjiag mebpgaodji ja EiPF eskmenndji 'Ejme % Pj]emon+
	0883(-
	Rce haopme ajmh ja EiPF0 dn a _ecakekod_e+ rceme oce L,oemhdiag mend_pe cjindnon ja a
	EiPF PL? ai_ qamdjpn nkgdcdib ai_ kmjcenndib dioemhe_daoen-'Nmjoedi( omaingaodji ktmjbgpoahaoe ai_ oce A,oemhdipn kjnnennen a bgtcdie,ahd_e-Rcene orj hj_dadcaodjin caqe
	ai_ kjnoomaingaodjiag hj_dadcaodjin ocao menpgo di oce adiag EiPF _ecakekod_e-gjib ]eei ocjpbco oj noa]dgdne don nompcopme ai_ ngjr don _ebma_aodji di oce ]gjj_ 'Acemojr+
	Ddbpme ha_e ]t Kagjie Q? 0870(+ rceme do can a iaodqe o 0.1 ja 1,3 hdipoen _pe oj makd_ kekod_ane _ebma_aodji ai_
	bgjhempgam adgomaodji-Rce ahdij acd_ nelpeice ja EiPF0 dn esomehegt cjinemqe_+ rdoc ieam
	d_eiodcag nelpeicen ]edib d_eiodade_ di agg hahhagn+ rdoc oce escekodji ja orj ahdij acd_
	np]nodopodjin di oce bpdiea kdb 'Hdheieiu,Jdiai eo ag-+ 0886(-

,(. :mPrgonWQ DrWUWn oT GnGH CScrona

	Njnoiaoaggt+ EiPF iepmjin kjnnenn neqemag ccamacoemdnodcn ocao gdfei oceh oj oce jocem
	kamqjceggpgam megeandib iepmjin ja oce ctkjocagahpn 'RPF+ APF+ EFPF eskmenndib iepmjin(
	di ocao ocet agg necmeoe a iepmjkekod_e dioj oce kjmoag cakdggamt ntnoeh ai_ ajmh oce akes ja a
	omdkamodoe aee_]acf asdn+ apgadggdib oce cmdoemda ja Fammdn _encmd]e_ di ccakoem G-Rce eh]mtjidc
	jmdbdi ja oce RPF+ EFPF ai_ APF eskmenndib iepmjin can ]eei _eoemhdie_ ]t di ndop

-(,(, HSfcOl RWTTSrSnbWObWon oT bVS mOlS UonOR

  Rce kmeneice ja oce QPW beie gea_n oj hjmkcjgjbdcag _daaemeiodaodji ja oce kmdhamt oenodcpgam bjia_ ao C01 di hdce+ rdoc oce _daaemeiodaodji ja Qemojgd ceggn amjh oce ajeoag oenoen hamfdib oce admno noek di oenodcpgam jmbaijbeiendn 'Kabme % Hjno 0880(-Rcene ceggn annjcdaoe rdoc eacc jocem

	]t dioem_dbdoaodjin ai_ heh]maie epicodjin+ kmjbmenndqegt eicjhkanndib oce bemh ceggn ai_ ocpn
	bdqdib mdne oj nehdidaemjpn cjm_n _egdhdoe_ ]t a ]anag heh]maie-?KF dn oce admno ei_jcmdie
	aacojm necmeoe_ ]t Qemojgd ceggn 'Rmai eo ag-+ 0866(+ ai_ dn admno _eoecoa]ge ao C0/-4 ai_ geqegn mdne
	piodg ]dmoc 'Iancdha_a % Ijjkhai+ 1/0/(-Gi maon ocdn kmjcenn ]ebdin ao C02 'Rnped eo ag-+ 0881(
	ai_ di cphain ?KF dn admno _eoecoa]ge ao 6 reefn ja benoaodji-
	Rce _daaemeiodaodji ja oce bjia_ dn _eoemhdie_ ]t oce beieodc nes di hjno hahhagn+ rdoc oce
	kmeneice ja a W ccmjhjnjhe cjioadidib oce QPW beie ]edib oce cmdodcag melpdmeheio di hjno
	epocemdai hahhagn 'Ep]]at eo ag-+ 088/: Qdicgadm eo ag-+ 088/(-Gi_ee_+ oce kmeneice ja QPW

ai_ Cda1n2t beien caqe ]eei ncjri oj ]e npaadcdeio oj mekgace oce W ccmjhjnjhe+ menpgodib di oce kmj_pcodji ja aemodge hage hdce di a_pgocjj_ 'Wahapccd eo ag-+ 1/03(-Rce odhdib ja ?KF eskmenndji ai_ necmeodji ]t oce Qemojgd ceggn dn odbcogt mebpgaoe_ 'mebpgaodji ja ?KF eskmenndji _dncpnne_ di 8VOpbSr -(.(+ an oce Küggemdai _pco jigt mehadin cjmhjiaggt neindodqe ajm a ncjmo kemdj_ ja odhe 'fijri an oce cmdodcag rdi_jr(+ jpond_e ja rcdcc oce Küggemdai _pcon rdgg aadg oj mebmenn 'Rabpccd eo ag-+ 0873: Rnped eo ag-+ 0881(-Rcdn rdi_jr dn amjpi_ C02.C03 di hdce ai_ akkeamn oj ]e _eoemhdie_ ]t oce eskmenndji ja mecekojmn a]ge oj ]di_ ?KF -?KFP1+ rdoc geqegn ncamkgt _ecmeane_ jpond_e ja oce cmdodcag rdi_jr 'Hjnnj eo ag-+ 1//0(-Rce mebmenndji ja oce Küggemdai _pco jice didodaoe_ ]t ?KF+ jccpmn di a cmaidj, cap_ag _dmecodji '?maibj eo ag-+ 1//7( ai_ dn dmmeqemnd]ge+ cjiodipdib eqei da ?KF dn ij gjibem kmeneio 'Rabpccd eo ag-+ 0873(-Rcdn dn cjindnoeio rdoc a kamacmdie acodji+ rdoc oce odnnpen cgjneno oj oce njpmce mebmenndib ]eajme _dnoag nompcopmen+ ai_ dn npkkjmoe_ ]t mame canen ja pidgaoemag Küggemdai _pco _emdqaodqen ]edib kmeneio di hagen aaoem ]dmoc+ 'e-b-kmeneice ja a ndibge oenodn( npcc an di hdse_ bjia_ag _tnbeiendn-Cqd_eice ajm a cjmhjiag maocem ocai kamacmdie acodji ji oce Küggemdai _pcon amdne amjh oce ameehamodi cjr-Dmeehamodidnh jccpmn rcei aianojhjnen ja oce ]gjj_ npkkgt oj ordi hage ai_ aehage cagqen ajmh+ rceme oce ?KF kmj_pce_ ]t oce oenoen ja oce ]pgg caga capnen mebmenndji ja oce Küggemdai _pcon di oce aehage caga 'meqdere_ ]t Cnoeqen eo ag-+ 1/01(-Rce mebmenndji ja oce Küggemdai _pcon jccpmn ocmjpbc admno mebpgaodib akjkojndn ocei mebpgaodib ekdocegdj,heneiccthag omainajmhaodji ja oce heneiccthag ceggn npmmjpi_dib oce Küggemdai _pcon qda ?KF ndbiaggdib '_d Ageheioe eo ag-+ 0883: Redsedma eo ag-+ 0885(-Gi maon oce cmdodcag

-(,(-ESraWabSnb BüllSrWOn 9cQb HgnRromS (EB9H)

	Rce ndbidadcaice ja ?KF ndbiaggdib oj oce _eqegjkheio ja cjmmeco hage beidoagda dn ncjri ]t
	hpoaodjin aaaecodib oce apicodji ja ?KF jm ?KF mecekojmn+ rcdcc ame fijri oj capne a mame
	ajmh ja dioemiag knep_j,cemhakcmj_dodnh cagge_ Nemndnoeio Küggemdai Bpco Qti_mjhe 'NKBQ(-
	Rcdn nti_mjhe dn ccamacoemdne_ ]t oce kemndnoeice ja Küggemdai _pco _emdqaodqen 'd-e-poempn+
	cemqds+ aaggjkdai op]en ai_ pkkem orj ocdm_n ja qabdia( di a kceijotkdcaggt ai_ famtjotkdcaggt
	hage '35VW( kaodeio-NKBQ kaodeion caqe ijmhag _eqegjkheio ja oce esoemiag beidoagda ai_
	necji_amt nespag ccamacoemdnodcn 'Peip eo ag-+ 1/0/(+ rdoc eamgt _eoecoa]ge nthkojhn hadigt
	cjiadie_ oj cmtkojmccd_dnh ai_ dibpdiag cemidan-Go dn otkdcaggt pkji np]nelpeio KPG jm _pmdib
	nkemhaodc qennegn jm qan _eaemein-
	?kkmjsdhaoegt 34% ja canen ja kemndnoeio Küggemdai _pco nti_mjhe ame capne_ ]t hpoaodjin di
	oce ?KF beie Yotke 0 'MKGK9 5//846(Z+ rcdge akkmjsdhaoegt 3/% ja canen ame capne_ ]t
	hpoaodjin di oce ?KFP1 beie Yotke 1 'MKGK9 5//845(Z-Gi oce mehadidib 04% ja canen+ ij
	hpoaodjin di oce ?KF ai_ ?KFP1 beien caqe ]eei d_eiodade_: cjreqem+ do dn agratn dicemdoe_
	di ai apojnjhag mecenndqe haiiem-
	Bjoc ?KF ,., ai_ ?KFP1 ,., hage hdce kmeneio oce nahe knep_jcemhakcmj_dodc
	kceijotke an neei di NKBQ kaodeion 'Becmdibem eo ag-+ 0883: Kdncdia eo ag-+ 0885(-

npmbemt oj omeao oce cemida+ ocao mehiaion ja oce Küggemdai nompcopmen ame _dncjqeme_+ heaidib ocao mekjmodib amelpeicden ajm oce cji_dodji ame gdfegt oj ]e pi_em,mekmeneioe_-? heoa,aiagtndn ja 151 cane mekjmon cjinompcoe_ a noaodnodcag hj_eg npbbenodib ocao hagdbiaicden ja oce Küggemdai odnnpen rjpg_ ]e eskemdeice_ ]t 2-0,7-3% ja NKBQ kaodeion rdocjpo npmbdcag dioemqeiodji 'Damdfpggac eo ag-+ 1/01( ai_ cdbcgt mecjhhei_e_ ocedm mehjqag-Amtkojmccd_dnh dn ocjpbco oj jccpm di NKBQ _pe oj hdn_dmecodji ai_ aiaojhdcag j]nompcodji ]t oce a]ijmhag kmeneice ai_ cjiiecodji oj oce Küggemdai nompcopmen+ maocem ocai a ncjmoeidib ja oce dioemiag Testis -(-

EoabnObOl rolSa oT 6BH -(-(1 6BH 6QbWona Wn ;SmOlS GSproRcQbWdS ;cnQbWon

	Gi ]joc mj_eio ai_ cphai nop_den+ do can ]eei abmee_ ocao ?KF necmeoe_ ]t kmdhamt ai_
	bmjrdib nhagg aiomag ajggdcgen acon an a ']mafe' dicd]dodib apmocem ajggdcpgam mecmpdoheio ai_
	_eqegjkheio-Dpmocem+ di qdomj aiagtndn ja DQF _ekei_eio ajggdcpgam haopmaodji dn cagoe_ ]t oce
	a__dodji ja ?KF+ di_dcaodib ocao ?KF dn dhkjmoaio di aooeipaodib ajggdcpgam neindodqdot oj
	Gi aehagen+ oce otkdcag cdmcpgaodib ?KF geqegn neei di ;WUcrS ,1 cjmmegaoe regg rdoc oce kme_dcodqe
	ctcgdcag DQF acodji 'Bpmgdibem eo ag-+ 1//0(-Rcdn dn npkkjmoe_ ]t a meceio nop_t ocao di_dcaoe_
	kjrem ja ?KF geqegn oj jqamdai menemqe 'Pjjde eo ag-+ 1//1( ocao can meceiogt ]eei rd_egt
	ocao ?KF geqegn kamaggeg agpcopaodjin di oce aiomag ajggdcge cjpio ocmjpbc oce heinompag ctcge
	a_jkoe_ an oce Ejg_ Qoai_am_ di kmdhamt ceagoc came ntnoehn 'Emtiiempk eo ag-+ 1/01( ai_ an a
	'Bekhaii eo ag-+ 1/05(-
	pneapg cj,kme_dcojm ja nodhpgaoe_ jqamdai menkjine 'Ja Kamca eo ag-+ 1/0/: Neñammp]da eo ag-+
	1//4(-Agdidcaggt j]nemqe_ cjmmegaodjin ]eoreei eicaice_ ]anag geqegn ja ?KF ai_ Njgtctnodc Gi nodop ct]md_dnaodji nop_den caqe ccamacoemdne_ ?KF ai_ don cjbiaoe ?KFP1 eskmenndji di
	bmaipgjna ceggn ja iji,aomeodc+ kme,aiomag ai_ nhagg aiomag ajggdcgen ]po ijo di gambem ajggdcgen
	'Bpmgdibem eo ag-+ 0888(-?KF ,., hdce caqe piagoeme_ jenomjpn ctcge geibocn cjreqem+ di_dcaodib
	a np]oge mjge di mebpgaodib jqamdai aemodgdot 'Bpmgdibem eo ag-+ 0888(-Rce apocjmn cjicgp_e_ ocao
	agocjpbc oce iph]em ja didodag kmdhjm_dag ajggdcgen aqadga]ge dhhe_daoegt ajggjrdib ]dmoc ran
	di_ekei_eio ja oce kmeneice ja ?KF+ do ran ai dhkjmoaio aacojm di dicd]dodib ajggdcpgam
	mecmpdoheio ai_ ocpn ?KF kmeneice ran enneiodag ajm kmjgjibdib aecpi_dot-?KF dn admno
	_eoecoa]ge di aehagen ao N3 di ]joc maon ai_ hdce+ cjdicd_dib rdoc didodaodji ja kmdhamt
	ajggdcpgjbeiendn 'Bpmgdibem eo ag-+ 1//1(-

Mqamt Qti_mjhe 'NAMQ( caqe ge_ oj a regg,_eqegjke_ kctndjgjbdcag mjge ajm ?KF di ajggdcpgam _eqegjkheio 'Peqdere_ ]t Aaooeap,Hjiam_ % Beradggt+ 1/00: Tdnnem+ 1/05(-Gi ocdn kaocjgjbt eicaice_ iph]emn ja kmdhamt ajggdcgen necmeoe a]ijmhaggt cdbc geqegn ja ?KF rcdcc menpgon di a _dhdidnce_ npkkmenndji ja ai_mjbei kmj_pcodji ai_ necmeodji cjpkge_ oj ammenoe_ ajggdcpgam haopmaodji-Kdce ocao ccmjidcaggt jqemeskmenn ?KF pi_em oce heoaggjocdjiedi,0 kmjhjojm kjnnenn aerem bemh ceggn di oce jqamden ao ]dmoc+ rdoc oce ojoag iph]em aaggdib oj uemj rdocdi 1 reefn 'Becmdibem eo ag-+ 088/(-Rcdn dn di cjiomano oj ?KF ,., hdce+ rcj caqe noaodnodcaggt dicmeane_ geqegn ja kmdhamt ai_ necji_amt ajggdcgen ao 14 _atn ai_ 3 hjiocn ja abe qemnpn ceoemjutbjpn ai_ rdg_ otke gdooemhaoen-Fjreqem+ ao 3 hjiocn ai_ 02 hjiocn+ _ecmeane_ iph]emn ja kmdhjm_dag ajggdcgen reme j]nemqe_ di ?KF ,., hdce+ npbbenodib a kmehaopme escapnodji ja jqamdai menemqe 'Baamei_n eo ag-+ 0884(-?KF % ?KFP1 hPL? eskmenndji geqegn ceoemjbeiejpngt _ecmeane ao jenompn 'di maon( ]po jocemrdne mehadi cjinoaio ocmjpbcjpo oce jenomjpn ctcge 'Baamei_n eo ag-+ 0884(-Gi qdomj eskemdheion ja cpgopme_ bmaipgjna ceggn caqe di_dcaoe_ ocao esjbeijpn ?KF _ecmeanen amjhaoane acodqdot ai_ Jpoedidndib Fjmhjie Pecekojm 'JFP( iph]em '_d Ageheioe eo ag-+ 0883( rcdgno dicd]dodib bmaipgjna cegg kmjgdaemaodji-Gi maon rdoc ccmjidcaggt cdbc JF+ oce jqamdai kjjg ja kmdhjm_dag ajggdcgen dn _ekgeoe_ ao ai dicmeane_ maoe 'Dgarn eo ag-+ 0886(-Njgthjmkcdnhn di ]joc ?KF ai_ ?KFP1 caqe ]eei annjcdaoe_ rdoc canen ja pieskgadie_ d_djkaocdc diaemodgdot di rjhei 'Pdbji eo ag-+ 1/0/( ai_ di a kjgtctnodc jqamt nti_mjhe 'NAMQ( cjcjmo+ a cji_dodji ocao dn kamogt ccamacoemdne_ ]t dicmeane_ nemph ?KF geqegn 'Eejmbjkjpgjn eo ag-+ 1/02(-Qeqemag ceoemjutbjpn hpoaodjin di ?KFP1 caqe agnj ]eei d_eiodade_ di a cjcjmo ja Fai Acdiene rjhei _dabijne_ rdoc kmdhamt jqamdai dinpaadcdeict 'NMG(+ rdoc di ndgdcj aiagtndn kme_dcodib oce _egeoemdjpn eaaecon ja ocmee qamdaion 'Jd eo ag-+ 1/05(-;WUcrS ,.( :TTSQba oT 6BH RcrWnU TollWQcloUSnSaWa( ?KF+ kmj_pce_ ]t oce bmaipgjna ceggn ja nhagg bmjrdib ajggdcgen+ dicd]don didodag ajggdcge mecmpdoheio ai_ DQF,_ekei_eio bmjroc ai_ negecodji ja kmeaiomag ai_ nhagg aiomag ajggdcgen-Gi a__dodji+ ?KF mehadin cdbcgt eskmenne_ di cphpgpn ceggn ja haopme ajggdcgen-Rce dineo ncjrn di hjme _eoadg oce dicd]dojmt eaaeco ja ?KF ji DQF,di_pce_ AWN08a0 eskmenndji gea_dib oj me_pce_ jenoma_djg 'C1( geqegn+ ai_ oce dicd]dojmt eaaeco ja C1 donega ji ?KF eskmenndji-R+ oenojnoemjie: Atk08a0+ amjhaoane-Ddbpme hj_dade_ amjh qai Fjpoei eo ag-'1/0/( -(

-(, 6BH 6QbWona Wn BOlS GSproRcQbWdS ;cnQbWon

  Rcene egecomjkctndjgjbdcag _aoa reme npkkjmoe_ ]t di qdqj a_hdidnomaodji ja ?KF _dmecogt dioj oce gaoemag qeiomdcgen ocao capne_ ai dicmeane di JF necmeodji elpdqageio oj geqegn melpdme_ oj kmj_pce ai jqpgaojmt npmbe-Go ncjpg_ agnj ]e ijoe_

	ag-+ 088/( -hage hdce ijmhaggt _j ijo caqe idkkgen-Nctndjgjbdcaggt+ ?KF geqegn aagg di ]jtn
	rdoc oce dicmeane di oenojnoemjie ai_ didodaodji ja nkemhaojbeiendn 'Pet eo ag-+ 1//4(: cjreqem+
	do ncjpg_ ]e ijoe_ ocao ocdn ocdn ai_mjbei he_daoe_ _ecmeane di ?KF geqegn dn menomdcoe_ oj kjno,
	iaoag gdae+ an dhhaopme Qemojgd ceggn gacf eskmenndji ja oce ?i_mjbei Pecekojm '?P( 'Bjpfamd eo ocao hjme ocai 7/% ja rjhei rdoc NAMQ akkeam oj caqe ai dicmeane_ JF kpgne amelpeict
	ag-+ 1//8: Acehen eo ag-+ 1//7(-Gioemenodibgt+ ?KF _eadcdeio hdce caqe cdmcpgaodib geqegn ja 'Ratgjm eo ag-+ 0886(+ npbbenodib ocao oce kpgne amelpeict ja EiPF dn kemndnoeiogt accegemaoe_ di
	oenojnoemjie rdocdi oce ijmhag maibe+ npbbenodib ocao cjhkeinaojmt heccaidnhn hat aco oj ocdn nti_mjhe-
	mekgace oce dioemcjiiecoe_ aee_]acf ]eoreei oce orj cjmhjien-Keaircdge hage hdce rdoc
	oambeoe_ hpoaodjin ja ?KFP1 _eqegjk Jet_db cegg ctkemkganda+ npbbenodib ai dicd]dojmt mjge ja ? haejmdot ja dhhaopme iepmjin di oce hjpne ]madi eskmenn ?KFP1+ npbbenodib ocao ?KF
	?KF ji Jet_db cegg kmjgdaemaodji 'Becmdibem eo ag-+ 0883(-ndbiaggdib hat ]e dhkjmoaio di mebpgaodib njhe iepmj_eqegjkheioag kmjcennen 'Je]epmmdem eo ag-+
	Bjoc Jet_db ai_ Qemojgd ceggn ja oce oenoen eskmenn ?KFP1 di_dcaodib a kjoeiodag kamacmdie mjge diomdbpdib lpenodji an oj ocedm mjge di mebpgaodib iepmjgjbdcag apicodji-Ddmno do hat ]e dhkjmoaio
	di mebpgaodib hage bjia_ag apicodji '?maibj eo ag-+ 1//7(-Gi_ee_+ cdbc _jnen ja ?KF menpgo di oj cjind_em oce cdmcpgaodib geqegn ja ?KF ajpi_ di haopme aidhagn+ ]edib mjpbcgt ndhdgam Gi a__dodji oj mebpgaodib EiPF necmeodji kjnoiaoaggt+ ?KF can agnj ]eei ncjri oj
	_ecmeane_ amjhaoane eskmenndji ai_ ceice oenojnoemjie necmeodji di qdomj 'Pacdie eo ag-+ 0887( ]eoreei tjpib a_pgon+ npbbenodib ocao oce mjge ja ?KF can _dnodico ai_ _dqembeio mjgen ]eoreei kmeaemeiodaggt nodhpgaoe necmeodji ai_ a_eijctkjkctneag beie eskmenndji ja oce bjia_jomjkdi
	ai_ di qdqj 'Japmdcc eo ag-+ 1//0(-Ajicjhdoaiogt+ ?KF agnj capnen a _ecmeane di JFP _eqegjkheio ai_ haopme apicodji-DQF di qdqj di maon 'Eammeg eo ag-+ 1/05(-Rcdn acodji ja ?KF ran nes,_ekei_eio+ ]edib
	eskmenndji+ rcdcc ncjpg_ apmocem aco oj _ecmeane oenojnoemjie necmeodji 'Pacdie eo ag-+ 0887(-Adhdij ai_ cjggeabpen '1/05( meceiogt picjqeme_ a _dmeco acodji ja ?KF ji EiPF iepmjiag menomdcoe_ oj aehagen ai_ jccpmmdib jigt ]eajme kp]emot-Gi qdomj aiagtndn _ehjinomaoe_ oce
	Rcdn dn cjiadmhe_ an hage hdce ocao jqemeskmenne_ ?KF pi_em oce cjiomjg ja oce nkecdadcdot ja ocdn menkjine pndib cegg gdien _emdqe_ amjh agg kdopdoamt cegg otken rdoc jigt oce
	heoaggjocdjiedi,0 kmjhjojm ncjre_ ccamacoemdnodc ndbin ja gjr ai_mjbei geqegn+ dicgp_dib
	qabdiag jkeidib+ pi_em_eqegjke_ Ujgaadai _pcon+ pi_encei_e_ oenoen ai_ idkkgen 'Becmdibem eo

Ucdgno necmeodib ?KF dioj oce kemdkcemag ]gjj_ cdmcpgaodji+ Qemojgd ceggn agnj necmeoe ?KF dioj oce nehdidaemjpn op]pgen+ rceme do esdnon ao a hpcc cdbcem cjiceiomaodji cjhkame_ oj oce kganha 'Daggao eo ag-+ 0886: Deidcceg eo ag-+ 0888(-Rce mjge ja ?KF di nehei dn cpmmeiogt picgeam-Pekjmon ja ?KF geqegn cjmmegaodib rdoc nkemh cjpio 'Rpooeghaii eo ag-+ 1//8(+ nkemh ijo kjnnenndib ?KFP1 'Baamei_n eo ag-+ 0883: Daggao eo ag-+ 0885( ai_ dhkmjqdib nkemh qda]dgdot jpond_e ja oce ]j_t 'Qdjr eo ag-+ 0887( ame neehdibgt cjioma_dcojmt--(-(-6BH 6QbWona on non-UonOROl HEG bWaacSa Gi oce a_pgo ]madi+ do can ]eei ncjri ocao haopme iepmjin eskmenn cdbc geqegn ja ?KF mecekojmn di ]joc nesen 'Je]epmmdem eo ag-+ 1//7: Uaib eo ag-+ 1//4: Uaib eo ag-+ 1//8(-Rcdn madnen oce acodqdot-Behjinomaodib ocao ?KFP1 dn eskmenne_ di a ndbidadcaio np]neo ja ctkjocagahdc EiPF iepmjin ]joc di hdce ai_ di cphain ai_ ocao esjbeijpn ?KF di_pcen iepmjiag acodqaodji ja akkmjsdhaoegt caga ja oce EiPF kjkpgaodji gjcaoe_ di oce NM? di hdce+ di_ekei_eio ja nes jm noabe ja oce jenomjpn ctcge-1//7: Uaib eo ag-+ 1//8(-Ajindnoeio rdoc ocdn+ omeaoheio ja hpmdie eh]mtjidc nkdiag hjojm ai_ cjmodcag iepmjin di qdomj rdoc ?KF dhkmjqe_ npmqdqag maoen 'Je]epmmdem eo ag-+ 1//7: Uaib eo ag-+ 1//4(-Rce hage dicmeane di nkdiag ai_ ceme]eggam hjojm iepmjin capne_ ]t ?KF he_daoe_ npmqdqag can ]eei ctkjocendne_ oj cjiomd]poe oj oce np]oge nes,]dane_ _daaemeicen di njhe ]ecaqdjpm kaooemin npcc an dicmeane_ eskgjmaojmt ]ecaqdjpm 'Uaib eo ag-+ 1//8(-?KF ndbiaggdib 'ocmjpbc ?KFP1 ai_ BKNP0]+ QK?B0.4.7( can ]eei ncjri oj mebpgaoe oce iepmjiag nemkdi iepmjnemkdi di a_pgo iepmjin ]joc di qdomj ai_ di qdqj 'Je]epmmdem eo ag-+ 1//7(-Lepmjnemkdi can ]eei _ehjinomaoe_ oj caqe neqemag mjgen di oce ALQ+ dicgp_dib oce cjiomjg ja iepmjiag hdbmaodji ai_ iepmjiag _eaoc 'Imtnojnef eo ag-+ 0870: Impebem eo ag-+ 0886: Weken eo ag-+ 1//1(-Giomdbpdibgt Adhdij ai_ cjggeabpen agnj _ehjinomaoe_ ocao hdbmaojmt EiPF iepmjin eskmenne_ ?KFP1 di ]joc cphain ai_ hdce+ madndib oce kjnnd]dgdot ocao ?KF ndbiaggdib hat agnj kgat a mjge mebpgaodib EiPF kmeiaoaggt-JβR1 bjia_jomjkc cegg gdie menkji_dib oj ?KF-Rce dicmeane di Dnc] omaincmdko geqegn ran _ekei_eio ji oce QK?B 0.4.7 kaocrat+ ndhdgam oj rcao can ]eei _encmd]e_ oj jccpm di oce

-(. 6BH4 ;rom GSnS bo ErobSWn

	Rce esaco ccmjhjnjhe kjndodjidib ja oce ?KF beie ran d_eiodade_ jie team aaoem don didodag
	nelpeicdib 'Aaoe eo ag-+ 0875( ai_ cBL? cgjidib 'Ndcam_ eo ag-+ 0875(+ gjcagdne_ cphai ?KF
	oj 08k02-2 'Ajcei,Fabpeiapem eo ag-+ 0876( ai_ oce hpmdie ?KF ji ccmjhjnjhe 0/ 'Idib
	eo ag-+ 0880(-Rce ?KF beie dn nhagg di ndue ao 1-64 f]k+ cjhkmdndib 4 esjin ai_ dn eimdcce_
	rdoc AE ]ane kadmn-Rce cphai ?KF beie eicj_en a 0-7 f]k hPL? ocao cjioadin a 4
	&piomaingaoe_ kamo ja 0/ ipcgejod_en-Rce kjgta_eitgaodji ndbiag dn kmeneio 8/ ipcgejod_en aaoem
	oce nojk cj_ji 'Aaoe eo ag-+ 0875(-Gi oce mao+ orj _dnodico hPL?n caqe ]eei _encmd]e_-Rcet

_daaem di oce geiboc ja ocedm kjgt? oadgn 'Jee eo ag-+ 0881(-? 1 f]k hPL? dn kme_jhdiaiogt kmeneio _pmdib ajeoag gdae ao oce odhe ja oenodcpgam _daaemeiodaodji ai_ _ecmeanen di oce gaoem noaben ja benoaodji+ rcdge a 0-7 f]k hPL? akkeamn ji _at 07 aaoem benoaodji 'N07( ai_ dn oce hjno a]pi_aiogt _eoecoe_ ajmh aaoem ocdn noabe 'Jee eo ag-+ 0881

(- -(.(

1 GSUclObWon oT bVS 6BH promobSr

  ocjne menkjind]ge ajm didodaodib eskmenndji di oce eh]mtjidc hage bjia_+ rcdgno dhkjmoaio mekmennjmn ja ?KF cai ]e d_eiodade_ di oce aehage eh]mtjidc bjia_-

	hage bjia_ag _eqegjkheio-Fphain rdoc ceoemjutbjpn ipgg hpoaodjin ajm QMV8 _eqegjk Kpoaodjin di B?V0 caqe ]eei dhkgdcaoe_ ]joc di V,gdife_ cjibeidoag a_meiag ctkjkganda ai_
	cahkjhegdc _tnkganda+ a geocag ]jie hagajmhaodji 'Djnoem eo ag-+ 0883(+ agocjpbc ja ijoe+ Gi hdce+ QD,0 eskmenndji dn didodaoe_ di oce beidoag md_ben ]ebdiidib ao C8 'Jpj eo ag-+ 0883(: an AFF 'Ra]amdi eo ag-+ 1///: Ha_caq eo ag-+ 1/01(-Rce pi_emgtdib capne ja AFF di Bas0 hpoaoe_
	akkmjsdhaoegt 64% ja hage QMV8 ceoemjutbjoen agnj ncjre_ nes meqemnag 'Kainjpm eo ag-+ kaodeion dn neehdibgt cjhkges+ rdoc B?V0 eskmenndji otkdcaggt ajpi_ ao agg geqegn ja oce FNE nespag _daaemeiodaodji cjhheicen+ QD,0 dn pkmebpgaoe_ di oce ajeoag oenoen ai_ _jrimebpgaoe_ Go can kmeqdjpngt ]eei mekjmoe_ ocao akkmjsdhaoegt 26/ ]k ja oce ?KF 4' agaifdib mebdji dn 0884(-?maibj ai_ cjggeabpen '0887( _ehjinomaoe_ ocao oce QMV8 BQ dn oce hjno cmdodcag mebdji asdn+ ai_ ocemeajme pihanfdib oce esaco capne ja oce kceijotke hat ]e hanfe_ ]t di oce jqamden+ npbbenodib do hat kgat a mjge di mebpgaodib ?KF acodqdot-Rce ?KF kmjhjojm enneiodag ajm don eskmenndji amjh C01-4 piodg eamgt kjnoiaoag noaben di oce hage hjpne 'Beap eo ajm _eoemhdidib ?KF eskmenndji; diodhaodib ocao QMV8 dn ocemeajme ]joc iecennamt ai_ a]ijmhagdoden di hpgodkge geqegn ja oce mekmj_pcodqe asdn-cjioadin a cjinemqe_ 1/ ]k hjoda 'KGQ,PC,0( ocao dn caka]ge ja ]di_dib QD,0 di qdomj '?maibj ag-+ 1//0(-Rcdn mebdji cjioadin jie QMV ]di_dib ndoe 'BQ( 'Be Qaioa Bam]ama eo ag-+ 0887(+ orj npaadcdeio ajm hage nes _eoemhdiaodji di ]joc hdce ai_ cphain-eo ag-+ 0888(+ ai_ QD,0 dn melpdme_ ajm oce pkmebpgaodji ja ?KF omaincmdkodji ]po ijo enneiodag QD,0 BQn 'Edpdgd eo ag-+ 0886: Qcei eo ag-+ 0883(+ jie E?R? BQ 'Tdbdem eo ag-+ 0887( ai_ jie UR0 BQ 'Laccodbag eo ag-+0887(+ agg ja rcdcc ame cdbcgt cjinemqe_ di epocemdai hahhagn ai_ QMV8 can ]eei ncjri oj mebpgaoe ?KF eskmenndji di kmeiaoag Qemojgd ceggn+ rcdgno do dn ijo ajm Küggemdai _pco mebmenndji '?maibj eo ag-+ 0888(-Rcdn ran _eoemhdie_ an hpoaodjin di oce -(/ HgnbVSaWa oT mObcrS 6BH
	hamnpkdagn 'meqdere_ ]t Nanf eo ag-+ 1//3(-eskmenne_ di a_pgo bmaipgjna ceggn 'orj regg,fijri odnnpe otken ocao necmeoe ?KF(-Rcdn dn QD,0 ]di_dib ndoe capne_ _mahaodc _ecmeanen di ?KF omaincmdko geqegn+ teo oce mebmenndji ja oce
	gdfegt capne_ ]t oce ULR .β,caoeidi kaocrat dicd]dodib oce eskmenndji ja QMV8 ai_ ceice Küggemdai _pco ntnoeh kmjcee_e_ oj cjhkgeodji-Go ran jigt rcei hpoaoe_ ai_ ipgg aggegen reme Rce ?KF beie eicj_en a kme,kmjkmjoedi ja 45/ ahdij acd_n di cphain-Go can a A,oemhdiag
	-(.(1(1 6QbWdObora oT bVS 6BH Eromobor
	;
	Gi hdce+ ?KF eskmenndji dn admno _eoecoe_ 1/c aaoem oce didodag eskmenndji ja QPW hafdib QPW
	donega a qemt gjbdcag cai_d_aoe oj mebpgaoe ?KF eskmenndji-QPW can ]eei ncjri oj acodqaoe a
	003]k ?KF kmjhjojm di qdomj+ rcdgno a hpoaodji di oce QPW ]di_dib _jhadi a]jgdnce_ ?KF KcJeiiai+ 1/02(-
	ncjri ocao ajm oce didodaodji ja ?KF omaincmdkodji+ jigt a kmjsdhag mebdji ja 26/]k dn iecennamt 'Beap eo ag-+ 1//0(+ don kjndodjidib ajggjrdib Qak51 heain do mend_en di a mebdji rceme oce ccmjhaodi dn ©jkei" ai_ oceme esdnon oce kjnnd]dgdot ocao kjnoiaoag mebpgaodji hat oafe kgace _dnoaggt+ rdocdi oce Qak51 beie-eskmenndji 'Fall eo ag-+ 0883(-? hpoaodji ja oce iji,cjineinpn QPW ]di_dib ndoe+ cjreqem+ 'oenodn,nkecdadc eicaicem ja QMV8( AMmeZ 'Njgaicj eo ag-+ 1//8: Qccekemn eo ag-+ 1//2(-iahe_ ajm oce BL? cjineinpn nelpeice do ]di_n-E?R?3 dn eskmenndji can ]eei ccamacoemdne_ Go can ]eei ncjri ocao oce L,oemhdiag kjmodji ja oce kmjoedi+ agocjpbc caqdib ij diomdindc _d_ ijo agoem ?KF eskmenndji+ oceme]t di_dcaodib ocao oce haejm mjge ja QPW di di_pcdib ?KF ?__dodjiaggt+ jqemeskmenndji ja QMV0/ capnen nes meqemnag di aehage hdce 'Njgaicj eo ag-+ 1//8(+ di ]joc kmeiaoag Qemojgd ceggn ai_ jqamdai bmaipgjna ceggn ai_ can ]eei ncjri oj omainacodqaoe acodqdot+ can oce mjge ja ahkgdatdib oce acodqdot ja oce A,oemhdipn 'Udgnji eo ag-+ 0882(+ rdoc eskmenndji jccpmn di_dmecogt 'Fall eo ag-+ 0883(+ dinoea_ kmdicdkaggt jccpmmdib ocmjpbc oce ai_ don _pkgdcaodji ji cphai ccmjhjnjhe 11l02 capnen 35VV oenodcpgam _dnjm_emn ja nespag oce ?KF kmjhjojm di bmaipgjna ceggn '?ioojiei eo ag-+ 1//2(+ a kmjcenn ocao dn iebaodqegt jigt oce ]djgjbdcaggt acodqe A,oemhdipn mebdji melpdme_ oj capne mebmenndji ja oce Küggemdai acodqaodji ja eqjgpodjiamdgt regg cjinemqe_ _jrinomeah acodqaojmn-_eqegjkheio '?gecf eo ag-+ 0888(-mebpgaoe_ ]t DME1 'amdei_ ja E?R?1(-Rce kmeneice ja ao geano jie E?R? BQ di oce ?KF _pcon 'Udgnji eo ag-+ 0882(-
	kmjhjojm npbbenon ocao E?R?3 hat mebpgaoe ?KF eskmenndji ]t _dmeco BL? ]di_dib 'Tdbdem
	Qeqemag _dmeco mebpgaojmn ja oce ?KF kmjhjojm caqe ]eei d_eiodade_ ai_ qagd_aoe_ pndib di qdqj Rafei ojbeocem+ ocene _aoa npbbeno ocao QMVC aahdgt heh]emn cai aco oj mebpgaoe hage,aehage eo ag-+ 0887( jm di cj,jkemaodji rdoc QD,0 'Rmeh]gat eo ag-+ 0888(-

?n oce eskmenndji ja ?KF escd]don a cdbc _ebmee ja nespag _dhjmkcdnh+ ai_ a nomdco oehkjmag mebpgaodji ja ?KF eskmenndji dn enneiodag ajm oce ega]jmaodji ja oce hage ai_ aehage kceijotken+ oce aacojmn mebpgaodib don omaincmdkodjiag acodqdot caqe ]eei nop_de_ di njhe _eoadg-Go ncjpg_ admno ]e ijoe_ ocao oce ?KF kmjhjojm dn gjcaoe_ 323]k _jrinomeah ja oce nojk cj_ji ja Qak51+ a p]dlpdojpngt eskmenne_ nkgdcejnjhe kmjoedi 'Bmennem eo ag-+ 0884(-Ucdge do can ]eei

hj_egn-Ucdge beiemaggt oce mebpgaodji ja ?KF mehadin ndhdgam ]eoreei hagen ai_ aehagen+ oce a]neice jm acodqe mekmenndji ja beien didodaodib hage nespag _daaemeiodaodji kmeqeion don kmeiaoag eskmenndji di oce _eqegjkdib aehage bjia_-Rcemeajme+ oce hjno dhkjmoaio acodqaojmn oj cjind_em hat ]e QPW 'Qes _eoemhdidib mebdji ji W( eskmenndji didodaoen oce hjgecpgam canca_en ocao rdgg menpgo di hage _daaemeiodaodji pi_em ijmhag kctndjgjbdcag cji_dodjin di hahhagn+ ai_ beien ocao ]ecjhe acodqaoe_ ncjmogt aaoem QPW ai_ mehadi acodqaoe_ ocmjpbc oce ©cmdodcag rdi_jr" ajmh bjj_ cai_d_aoen ocao hat mebpgaoe ?KF beie acodqdot-

-(.(1(, HGN (HSf RSbSrmWnWnU rSUWon on N)

?KF di oce aehage bjia_ 'Bemiam_ eo ag-+ 1/01(-Gi_ee_+ β,caoeidi hat kmeqeio oce ]di_dib ja QD,0 oj oce QMV8 eicaicem mebdji ai_ ocpn oce _daaemeiodaodji ja Qemojgd ceggn-?__dodjiaggt+ acodqaodji ja ocdn mjpoe di pi_daaemeiodaoe_ hage bjia_n ja hdce 'C00-4( di_pcen nespag meqemndji-Pnkj0 YP,nkji_di cjhjgjb 'seijkpn gaeqdn(Z+ Uio3 'rdibgenn,otke KKRT dioebmaodji ndoe aahdgt heh]em 3( ai_ Djsg1 'ajmfcea_ ]js J1( kaocratn ame agg acodqaoe_ ao C00-4,01-4 di oce jqamt ai_ cjiqembe oj mekmenn oce eskmenndji ja QMV8 ai_ np]nelpeio hage _daaemeiodaodji-Ma ijoe+ QMV8 ]egjibn oj oce QMVC aahdgt ja omaincmdkodji aacojmn+ agg ja rcdcc ame eskmenne_ ]t oce oenoen _pmdib hahhagdai oenoen _daaemeiodaodji 'Qccekemn eo ag-+ 1//1: Qccekemn eo ag-+ 1//2(-Gi qdomj nop_den caqe ncjri ocao jocem QMVC aahdgt heh]emn 'QMV7 ai_ QMV0/( cai acodqaoe oce ?KF kmjhjojm ndhdgamgt oj QMV8 -cjpkge_ oj QD,0 ai_ acodib qda RCQAM YRCQ bjia_ag _daaemeiodaodji qda ?KF+ ai_ enkecdaggt QMV8 acodqaodji menpgon di ?KF acodqaodji eqei di hahhagn rceme ij W ccmjhjnjhe dn kmeneio 'Moafe eo ag-+ 1/05(-

-(.(1(. H;-1 (HbSroWRoUSnWQ TOQbor 1)

cjh]die_+ kpncdib ?KF geqegn kano a cmdodcag ocmencjg_+ ocao Küggemdai nompcopmen apmoceno amjh oce oenoen reme meoadie_ '?maibj eo ag-+ 0888(-Rcao Küggemdai _pco mebmenndji jccpmme_ eqei rcei ?KF omaincmdko geqegn reme nj ceaqdgt me_pce_ ]t hpoaodji ja QD,0 ]di_dib ndoen+ rcdcc npbbenon ocao ?KF geqegn _pmdib oce nespag _dhjmkcdc rdi_jr ame ndbidadcaiogt di escenn ja rcao dn melpdme_ ajm Küggemdai _pcon mebmenndji-QD,0 can ]eei ncjri oj aco ntiembdnodcaggt rdoc jocem regg,fijri acodqaojmn ja ?KF oj kmjhjoe don eskmenndji dicgp_dib QMV8+ UR0 ai_ E?R?3-QD,0 hat ocemeajme ]e dhkjmoaio di mebpgaodib ?KF geqegn di jm_em oj aacdgdoaoe acodjin ji iji,Küggemdai nompcopmen+ jm oj mebpgaoe ?KF geqegn kjnoiaoaggt-

-(.(1(/ G6I6.

E?R?3 dn a heh]em ja oce E?R? ipcgejod_e ]di_dib aahdgt ja udic adibem omaincmdkodji aacojmn+ _jhadi cammtdib ]djgjbdcag acodqdot ai_ ai L,oemhdiag _jhadi ocao dn kpmkjmoe_ oj ]e _eqjd_ ja diomdindc acodqdot-Rce A,oemhdiag kjmodji ja 038 ahdij acd_n dn cdbcgt cjinemqe_ ]eoreei nkecden ai_ ncamen =2/% cjhjgjbt rdoc jocem bmjroc aacojmn ja oce REDβ aahdgt-Djggjrdib mehjqag ja oce admno 13 ahdij acd_n _pmdib ntiocendn+ ?KF dn mecjbidna]ge an a 03/ fBa bgtcjkmjoedi+ cjhkjne_ ja orj hjijhemn ja 6/ fBa+ noa]dgdne_ ]t _dnpgad_e ]md_ben 'Ndcam_ ai_ Hjnnj 0873(-Jdfe hait hjgecpgen ja oce REDβ npkemaahdgt+ ?KF hpno ocei ]e cgeaqe_ dioj orj L ai_ A oemhdiag _dhemn oj aclpdme don ]djgjbdcag apicodji-Rce cgeaqabe ja ?KF bdqen mdne oj a 00/ fBa L,oemhdiag cjhj_dhem ajmhe_ ]t orj 46 fBa np]pidon ai_ a 14 fBa acodqe A cjhj_dhem cjhkjne_ ja orj d_eiodcag 01-4 fBa np]pidon-Rce iji,cjqageio cjhkges ai_ kmj, cjmhjie ame oce orj ajmhn kme_jhdiaiogt ajpi_ di oce ]gjj_ ja cphain 'Naifcpmno %

WUcrS ,1( BolSQclOr bWmWnU oT bVS QrWbWQOl eWnRoe oT aSfcOl RSbSrmWnObWon Wn mWQS( Qespag

  KF di oce eh]mtjidc mao oenodcge 'Laccodbag ai_ Gibmacah 0885(-?__dodjiaggt+ jigt NA4 dn caka]ge ja cgeaqdib ocdn cjmhjie aaoem cj,omainaecodji dioj hahhagdai ceggn-Go dn agnj ijoerjmoct ocao ocene cjiqemoanen caqe ]eei ncjri oj ]e eskmenne_

	]t iepmjin 'Aadi eo ag-+ 1//2(-
	Rcene menpgon kmdhamdgt npbbeno ocao ?KF dn cgeaqe_ ao don ndoe ja necmeodji-Fjreqem+ jocem
	eskemdheion ncjre_ ocao jigt 4,04% cgeaqe_ ?KF ran kmeneio di oce nemph ai_ dicp]aodji
	he_dph ja oce caga oenoen-Rcdn annphen a kjoeiodag cgeaqabe ao oce ndoe ja acodji ja oce cjmhjie
	maocem ocai ao oce geqeg ja oce kmj_pcdib ceggn 'Laccodbag ai_ Gibmacah 0885(-
	meaccdib keaf eskmenndji ]eoreei C01 ai_ C02-4-QMV8 dn jie ja oce fet mebpgaojmn
	ja ?KF eskmenndji ocao didodaoen oce mebmenndji ja oce Küggemdai _pco-Mpond_e ja dioemacodji ja ?KF rdoc don mecekojm ?KFP1 '_d Ageheioe eo ag-+ 1/0/(-Djggjrdib don kme,
	ocdn cmdodcag rdi_jr+ oce eh]mtjidc bjia_n ]ecjhe cjmhjiaggt dineindodqe ai_ cgeaqabe+ oce L ai_ A,oemhdiag kjmodjin ja oce ?KF mehadi annjcdaoe_ ]t iji,cjqageio ]ji_n
	mebmenndji ja jie kadm ja _pcon caiijo ]e didodaoe_-?_akoe_ amjh Iancdha_a % ai_ ]di_ oj ?KFP1 di ocdn ajmh-Bdi_dib oj oce mecekojm di_pcen _dnnjcdaodji ja oce L,
	Ijjkhai 1/0/
	oemhdiag kmj,mebdji ai_ hafen do kjnnd]ge oj beiemaoe oce haopme gdbai_ caka]ge ja ]djacodqe
	?n _eoemhdie_ eskemdheioaggt di qdomj+ mecjh]diaio ?KF cai ]e cgeaqe_ ]t kganhdi 'Nekdinft ndbiaggdib-
	eo ag-+ 0877(-Fjreqem+ di qdqj+ oce eiuthen caka]ge ja cgeaqdib ?KF mehadi gambegt pifijri-?KF cgeamaice amjh oce ]gjj_ can ]eei _eoemhdie_ di cphain ]t CJGQ? ja aehage kaodeion

_daaemeiodaodji ja oce bjia_n megden ji oce kmecdne acodqaodji ja a ndbiaggdib canca_e ocao diqjgqen iphemjpn beien-Djggjrdib oce akkeamaice ja oce ]dkjoeiodag bjia_ ao C0/-4+ oce eskmenndji ja QPW 'nes _eoemhdidib mebdji ji W( meaccen a keaf ao C00-4-? aer cjpmn gaoem+ QMV8 omaincmdkodji ]ecjhen acodqaoe_ di oce oenodn+ ?gocjpbc oce ndoe ja cgeaqabe oj ajmh oce ]dj,acodqe ?KF dn cpmmeiogt pifijri+ np]odgdndi.fesdi,gdfe kmjkmjoedi cjiqemoanen ame ocjpbco oj ]e menkjind]ge ajm ?KF cgeaqabe ai_ nop_den caqe ncjri ocao apmdi ai_ kmjcjmhjie cjiqemoane 'NA4(+ orj npcc ei_jkmjoeanen+ reme cj,eskmenne_ rdoc ?Rce cdmcpgaodib geqegn ja neqemag heh]emn ja oce REDβ aahdgt ame mebpgaoe_ ]t ocedm dioemacodji rdoc ]di_dib kmjoedin 'e-b-acodqdin ai_ ajggdnoaodin(-? meceio _jcojmag ocendn njpbco oj d_eiodat rceocem ?KF geqegn reme agnj mebpgaoe_ ]t ]di_dib kmjoedin+ ai_ oceme]t agnj kmjqd_e njhe cgpen an oj don ndoe ja cgeaqabe 'Iarabdncd+ 1/04: Iarabdncd eo ag-+ 1/06(-Rce ajggdnoaodin ca_ oce bmeaoeno eaaeco ji ?KF ndbiaggdib Y_eoecoe_ ]t 'BPC(1,Jpc mekjmoem annat di N08 ceggnZ+ cjreqem+ oce eaaeco ran jigt ajpi_ ao gjr ?KF cjiceiomaodjin+ cjhkama]ge oj a_pgo cdmcpgaodib geqegn 'Iarabdncd eo ag-+ 1/06(-Qeqemag ]di_dib kmjoedin reme ncjri oj caqe a nhagg eaaeco ji np] CA 4/ cjiceiomaodjin ja oce ?KF A,oemhdiag di_pce_ ndbiaggdib+ dicgp_dib ]mjmdi ai_ _ecjmdi+ di_dcaodib ocao ?KF cgeaqabe hjno gdfegt jccpmn ao don ndoe ja acodji-Gi 1/0/+ oce oeah ja _d Ageheioe ai_ Aaoe kmjkjne_ ocao cgeaqabe jccpmn ajggjrdib oce ]eajme pi_embjdib cjh]die_ ctnoemecojht ai_ ]dgaoemag nagkdibj,jjkcjmecojht+ ai_ ji cjinecpodqe _atn ajggjrdib oce npmbemt 'Emdendibem eo ag-+ 1/01(-Rce caga,gdae ja ?KF ran ± -(

0 6BH aWUnOllWnU -(0(1 IrOnaTormWnU GroebV ;OQbor-j (IG;j) ;OmWlg

	ncjri oj dioemaco rdoc ocmee otke G mecekojmn ja oce ?codqdi gdfe fdiane '?JI( aahdgt -?cqP0
	'?codqdi mecekojm 09 ?JI1(+ BKNP0a 'Bjie hjmkcjbeidc kmjoedi mecekojm 0?9 ?JI2( ai_
	BKNP0] 'Bjie hjmkcjbeidc kmjoedi mecekojm 0B9 ?JI5(-?gg ocmee otke G mecekojmn acodqaoe
	oce caijidcag QK?B 0.4.7'8( kaocrat 'Qee ;WUcrS -1(
	?KF dn a _dqembeio heh]em ja oce REDβ npkemaahdgt+ a bmjpk cjindnodib ja jqem 2/ kmjoedi
	ndbiaggdib hjgecpgen-Rce ]djgjbdcag dhkjmoaice ja oce REDβ aahdgt esoei_n oj a rd_e qamdeot
	ja kctndjgjbdcag kmjcennen dicgp_dib9 _eqegjkheio 'e-b-ctojnfegeoag jmbaidnaodji ai_ REDβ0+ 1+ 2 Nmjgdaemaodji ai_ _daaemeiodaodji ja hdbmaodji(+ kmjgdaemaodji ai_ ceggpgam _daaemeiodaodji 'Uaoa]e % Kdtaujij+ 1//8: meqdere_ ]t IgpS I GSQSpbor 6lbSrnObWdS nOmSa AWUOnRa :fOmplSa oT rSUclOborg rolSa ;WUcrS ,3
	Uednn % ?oodnaij+ 1/02( ai_ dicgp_en acodqdin+ REDβn+ ij_agn+ ]jie hjmkcjbeidc kmjoedin RnP0 ?JI0 ?codqdin ei_jocegdag ceggn
			BKN,8+ 0/	?codqaodji ja aibdjbeiendn
			6BH	Küggemdai _pco mebmenndji
	6QdG1	?JI1+ QfP0+ ?ARP0?	?coqdin BKN,5+ 6+ 8	Feamo hjmkcjgjbt Nmjhjoen ccji_mjctoe _daaemeiodaodji
			REDβ	Ch]mtjidc kaooemidib
	7BEG1O	?JI2+ Bmf0	6BH BKN,1+ 3+ 4+ 5+ 6+ 0/ EBD4+ 5+ 8	Küggemdai _pco mebmenndji Ch]mtjidc kaooemidib Mnoej]gano _daaemeiodaodji Feamo hjmkcjgjbt Acji_mjctoe _daaemeiodaodji
	?cqP0]	?JI3+ QfP1+ ?coP0]	?codqdin Lj_ag Ktjnoaodi	Ch]mtjidc kaooemidib Feam hjmkcjgjbt Gicd]don a_eijctkjkctneag kmjgdaemaodji Giagahhaojmt menkjine
	RβP0	?JI4	REDβn EBD8 Ktjnoaodi	Pebpgaoen esomaceggpgam haomds Rctmjd_ apicodji Aeggpgam akjkojndn Aeggpgam hdbmaodji ai_ diqandji
	Gi qemoe]maoen+ agg heh]emn ja oce REDβaahdgt ncame oce pne ja epno 6 otke G mecekojmn+ rcdgno 7BEG1P ?JI5 Djggdcpgjbeiendn ai_ jqpgaodji 6BH ?kkei_dcpgam nfegeoag _eqegjkheio BKN,1+ 3,6+ 0/+ 04 Bdaaeemeiodaodji ja jnoej]ganon EBD4+ 5+ 8 Njnoiaoag ]jie ajmhaodji oce 4 otke GG mecekojmn hat edocem ]e nkecdadc ajm neqemag jm epno jie ndibge gdbai_-Rcemeajme+ pi_emnoai_dib oce hjgecpgam ]andn ajm oce _dqemne acodqdoden ja ocene hpgodapicodjiag aacojmn dn ?cqP0c ?JI6 Ch]mtjidc kaooemidib ?codqdin Becmeanen cegg kmjgdaemaodji Lj_ag Gicmeanen cegg akjkojndn
	cjhkges+ an di a__dodji oj oce kmjhdncpdot ja oce mecekojm cjhkgesen+ oce diomaceggpgam menkjinen
	ame ]joc _eqegjkheioag+ ai_ cegg,cjioeso _ekei_eio-IOPlS ,( IgpS I IG;j rSQSpbor lWUOnRa OnR Ynoen TcnQbWona
	a_akoe_ amjh Qe_en J+ 1/03

'BKNn( jm bmjroc ai_ _daaemeiodaodji aacojmn 'EBDn

(-REDβ aahdgt heh]

emn ndbiag ocmjpbc a ceoemjhemdc cjhkges ja omainheh]maie nemdie,ocmejidie fdiane mecekojmn ocao melpdmen oce annjcdaodji ja orj _daaemeio otken ja mecekojm cgann-Gi qemoe]maoen+ oceme esdno gdbai_ ]di_dib mecekojmn 'otke GG( ocao otkdcaggt mecmpdo otke G mecekojmn ocao kjnnenn oce a]dgdot oj cjiaem ndbiag omain_pcodji 'Kjpnoafan % Feg_di+ 1//8(-Kjme nkecdadcaggt+ do can ]eei ncjri ocao REDβn ndbiag ocmjpbc a _dhemdne_ gdbai_ ai_ ai acodqaoe_ cjhkges cjhkmdne_ ja orj otke GG mecekojmn ai_ orj otke G mecekojmn+ agocjpbc oceme esdno _dqemne hjgecpgam heccaidnhn ocmjpbc rcdcc ocdn hat ]e ]mjpbco a]jpo 'meqdere_ ]t Qcchdemem % Fdgg+ 1//6(-Mice oce acodqe cjhkges dn ]mjpbco a]jpo+ oce otke GG mecekojm fdiane+ rcdcc dn cjinodopodqegt acodqe+ kcjnkcjmtgaoen oce diomaceggpgam EgtQem _jhadi ja oce otke G mecekojm+ ocpn acodqaodib don fdiane acodqdot ai_ menpgodib di oce kcjnkcjmtgaodji ja QK?B kmjoedin ocao ame annjcdaoe_ rdoc otke G mecekojmn-?KF can ]eei ncjri oj ]di_ escgpndqegt oj jie otke GG mecekojm+ ?KFP1+ rcdgno ij jocem gdbai_ can ]eei ncjri oj caqe eaaecodqe ]di_dib oj do 'Kdncdia eo ag-+ 0885(-?KFP1 can ]eei

( IG;β TOmWlg mSmPSra OnR bVSWr QoUnObS rSQSpbora(

	qamdaion reme ajpi_ di ]joc hdce ai_ maon+ rdoc oce kmjkjmodji ja ojoag ?KFP1 hPL? -(1(-7onS BorpVoUSnSbWQ ErobSWn GSQSpbor 1O (7BEG1O)6AK-)
	mekmeneioe_ ]t ocene orj dnjajmhn enodhaoe_ ao pi_em 4%-Dpmocem rjmf dn melpdme_ oj ]eooem BKNP0a dn eskmenne_ di oce Küggemdai _pco heneiccthe agjib rdoc ?KFP1 ai_ ?cqP0+ ]po
	egpcd_aoe ocedm kctndjgjbdcag mjgen-_jhdiaio,iebaodqe ajmhn _j ijo ]gjcf oce ?KF,nodhpgaoe_ QK?B0.4.7 kaocrat 'Agamfe eo
	Rce heccaidnh ocmjpbc rcdcc ?KF dioemacon rdoc ?KFP1 dn gdfegt _dnodico amjh jocem ag-+ 1//0: Ejpe_am_ eo ag-+ 1///(-Fjreqem+ di qdqj cji_dodjiag diacodqaodji ja BKNP0a pndib
	heh]emn ja oce REDβ aahdgt '_d Ageheioe eo ag-+ 1/0/(-Go can ]eei kmjkjne_ ocao cgeaqabe ja ai ?KFP199Ame aggege menpgoe_ di oce meoeiodji ja oce Küggemdai _pco di ∼4/% ja oce hage hdce
	apgg,geiboc ?KF menpgon di a cjiajmhaodjiag ccaibe di oce A,oemhdiag _jhadi rcdcc aacdgdoaoen 'Hahdi eo ag-+ 1//1(+ rcdgno jqemeskmenndji ja a cphai ?KF omainbeie di BKNP0a cji_dodjiag
	mecekojm ]di_dib ';WUcrS -*(-Bdi_dib ja ?KFP1 di_pcen oce _dnnjcdaodji ja oce kmj,mebdji qda hpoaion+ menpgoe_ di cjhkgeoe mebmenndji ja oce Küggemdai _pcon 'Hahdi eo ag-+ 1//2(-
	a iebaodqe aggjnoemdc dioemacodji ]eoreei oce mecekojm, ai_ kmj,mebdji,]di_dib ndoen ji oce A, ?ijocem bmjpk rcj ehkgjte_ cji_dodjiag _egeodji ja BKNP0a pndib ai ?KFP199Ame aggege
	ocmjpbc a cjh]diaodji ja ?cqP0+ BKNP0a ai_ BKNP0]-BKN6 ncamen agg ocmee cj,mecekojmn
	ai_ dn agmea_t fijri oj ncame neqemag ndhdgam mjgen rdoc ?KF+ dicgp_dib an iepmjiag npmqdqag beie kmjhjojm _mdqen oce eskmenndji ja oce Ame mecjh]diane eiuthe 'escdndib oce nojk cj_ji
	aacojmn 'Wa]e eo ag-+ 1//1: Uaib eo ag-+ 1//4( ai_ mebpgaojmn ja ]jie _eqegjkheio '?_ahn+ ocao dioemmpkon oce eskmenndji ja JacX(+ ai_ jice acodqaodji can jccpmme_+ oce JacX beie caiijo
	1/01(-Ucdge oce agmea_t fijri acodjin ja oce otke G mecekojmn cai kmjqd_e cgpen a]jpo kjoeiodag ]e diacodqaoe_-Rcemeajme+ oce noadidib ocao dn neei ao ait bdqei kjdio di odhe hat ijo ]e a ompe
	mjgen ja ?KF ndbiaggdib+ oce rd_enkmea_ eskmenndji ja otke G mecekojmn ai_ oce cegg otke meagecodji ja oce eskmenndji ja oce ?KFP1 kmjoedi+ maocem di_dcaodib ocao oce ceggn 'jm ocedm
	_ekei_eio cjioeso ja otke GG mecekojm eskmenndji heai njhe capodji ncjpg_ ]e pmbe_ rcei hjocemn( jice ca_ ai acodqaoe_ ?KFP1 kmjhjojm-
	kmjkjndib ijqeg mjgen ajm ?KF-?KF dn+ cjreqem+ oce jigt fijri gdbai_ ajm ?KFP1 ai_
	ocemeajme ?KFP1 eskmenndji di odnnpen iecenndoaoen a nkecdadc mjge ajm ?KF ndbiaggdib rdocdi
	oce odnnpe-

? nccehaodc dggpnomaodib oce cjhkges jqemgakkdib ja gdbai_,mecekojm cjh]diaodjin ocao cai jccpm di REDβ aahdgt ndbiaggdib-Cacc otke GG gdbai_ ]di_dib mecekojm cai _dhemdne rdoc hpgodkge ncame_ otke G mecekojmn di jm_em oj di_pce diomaceggpgam ndbiaggdib kaocratn-?KF dn oce jigt fijri gdbai_ ja ?KFP1 ai_ don ndbiaggdib melpdmen _dhemdnaodji rdoc jie ja ocmee otke G mecekojmn+ eacc ja ocene otke G mecekojmn dn ncame_ rdoc eqemt heh]em ja oce npkemaahdgt rdoc oce escekodji ja oce ompe REDβn-Ddbpme ha_e ]t Kagjie Q?--(1 6BH GSQSpbora ?KF dn npnkecoe_ oj jigt caqe jie gdbai_ ]di_dib mecekojm 'Tdnnem+ 1//2( an ?KF ,., hdce ame a kceijcjkt ja ?KFP1 ,., hdce 'Kdncdia eo ag-+ 0885(-?n ?KF dn enneiodag oj oce mebmenndji ja oce Küggemdai _pcon+ ?n di_dcaoe_ di ;WUcrS ,3+ ?KF dn ijo oce jigt heh]em ja oce REDβ aahdgt ocao ndbiagn oemhdiag _dhem-Go dn cpmmeiogt pifijri rceocem kmj,mebdji _dnnjcdaodji jccpmn ]eajme eibabeheio rdoc ?KFP1 ]po do dn pigdfegt ocao amee A,oemhdiag ?KF esdnon an do oei_n oj abbmebaoe ao iepomag kF-Rcdn heccaidnh dn agnj npkkjmoe_ ]t kmeqdjpn mekjmon ocao oce kpmdade_ A,oemhdiag _dhem dn genn ]djgjbdcaggt acodqe ]t a aacojm ja 0/ cjhkame_ oj cgeaqe_ ?KF+ rdoc apgg acodqdot menojme_ ]t me,a__dodji ja oce kmj,mebdji rcdcc ajmhn a cjhkges rdoc oce A, oemhdiag _dhem 'Udgnji eo ag-+ 0882(-Nmeiaoaggt+ ?KFP1 eskmenndji can ]eei regg ccamacoemdne_ di oce henjekdocegdag ceggn ja oce Küggemdai _pcon+ ajeoag gpibn 'Aaogdi eo ag-+ 088/: Aaogdi eo ag-+ 0886( ai_ eh]mtjidc hjojm iepmjin 'Uaib eo ag-+ 1//4(-?__dodjiaggt+ oce podgdnaodji ja oce ?KFP1 *.Ame JacX * hjpne ao C07 d_eiodade_ rd_enkmea_ β,bag noadidib+ di oce9 gpibn+ nkdiag cjm_+ kemdkcemag baibgda+ ]madi+ oenoen ai_ agg ekdocegdag odnnpen+ ahjibno jocemn '?_ahn+ 1/01(-Mie caqeao ocao dn dhkjmoaio oj cjind_em rcei dioemkmeodib ocene menpgon+ dn+ di ocdn hj_eg oce ei_jbeijpn acodqdot ja oce ?KFP1 nkecdadcaggt mehjqe_ eskmenndji ja BKNP0a amjh oce heneiccthe ja oce Küggemdai _pco ai_ menpgoe_ di ∼44% ja oce hpoaio hagen meoadidib Küggemdai _pcon+ npbbenodib ocao BKNP0a dn oce kmdhamt otke G mecekojm diqjgqe_ di he_daodib Küggemdai _pco mebmenndji di qdqj 'Mmqdn eo ag-+ 1//7(-BKNP0a can ]eei ncjri oj omain_pce ?KF ndbiaggdib ]t acodqaodib oce QK?B0 kaocrat di oce QK?R,0 Qemojgd cegg gdie 'Begqdgge eo ag-+ 1//4(-Atk06c ** hdce reme cmjnne_ rdoc BKNP0a gjsk.gjsk hdce oj j]oadi cji_dodjiag fijcfjpo hdce rceme oce BKNP0a beie ran nkecdadcaggt diqagd_aoe_ di Jet_db ceggn-Rcdn _egeodji agoeme_ oce ntiocendn ja ai_mjbein an regg an oce haopmaodji ai_ _daaemeiodaodji ja Jet_db ceggn 'Up eo ag-+ 1/01(-Qdice oce apocjmn ca_ kmeqdjpngt j]nemqe_ kceijotkdcaggt cjhkama]ge Jet_db ceggn di ?KF ,., hdce 'Up eo ag-+ 1//4(+ ocet cjicgp_e_ ocao ?KFP1.BKNP0a dioemacodjin he_daoe_ ?KF ndbiaggdib di Jet_db ceggn--(1(.

7onS BorpVoUSnSbWQ ErobSWn GSQSpbor 1P (7BEG1P)6AK0)

  BKNP0] eskmenndji can ]eei ncjri di ]joc hage ai_ aehage mao eh]mtjn aoC04-4 di oce ekdocegdph ja oce Küggemdai ai_ Ujgaadai _pcon+ ]po ijo di oce heneiccthe npmmjpi_dib oce _pcon 'Agamfe eo ag-+ 1//0(-?n ?KFP1 eskmenndji dn kme_jhdiaiogt di oce heneiccthe npmmjpi_dib oce _pcon+ ocdn npkkjmon _aoa amjh oce hage BKNP0] ,., hdce+ ocao _j ijo escd]do ait eqd_eice ja Küggemdai _pco meoeiodji 'Agamfe eo ag-+ 1//0(-Rce aehage ipgg hdce pi_embj ijmhag bjia_ag _eqegjkheio+ di_dcaodib ocao BKNP0] ndbiaggdib dn ijo enneiodag ajm Küggemdai _pco ajmhaodji jm mebmenndji-Rcdn dn npkkjmoe_ ]t es qdqj nop_den ja Küggemdai _pco mebmenndji ocao caqe ncjri ocao kme,omeaoheio rdoc ai aiodneine BKNP0] hjmkcjgdij jgdbjhemn ca_ ij eaaeco ji ?KF,di_pce_ mebmenndji ja oce Küggemdai _pcon 'Tdnnem eo ag-+ 1//0(-Gi jm_em oj nop_t oce eaaeco ja oce a]neice ja ULR3 ji oce a_pgo jqamt+ cji_dodjiag fijcfjpo hdce reme beiemaoe_-Gi ?KFP199cme:Uio3 gjsk.gjsk hdce+ eskmenndji ja Uio3 dn a]jgdnce_ jigt di bmaipgjna ceggn 'Bjtem eo ag-+ 1/0/(-Ajindnoeio rdoc ULR3 ]edib a kjoeiodag ndbiaggdib oambeo

	mebpgaoe_ QK?Bn 'P,QK?B(+ cj,he_daojm QK?Bn 'Aj,QK?B. QK?B3( ai_ oce dicd]dojmt QK?B7 dicmeane_ oce mekjmoem acodqdot di menkjine oj ?KF nodhpgaodji+ rcdgno jqemeskmenndji .(1 6Wma " DPXSQbWdSa ?ijocem _eqegjkheioag _dnjm_em+ oce diaemodgdot nti_mjhe cjibeidoag ctkjbjia_jomjkdc ajggjrdib kmdhemn reme pne_ 'IOPlS -(-Migt 1/ eh]mtjn cjpg_ ]e annenne_+ an kmdjm odnnpe IOPlS .( HcmOn aOmplSa ajggjrdib _at+ nahkgen reme me,ct_maoe_ ajm 0cm ao PR di _encei_dib cjiceiomaodjin ja
	QK?Bn 'G,QK?B. QK?B5+ 6( 'Feg_di eo ag-+ 0886(-P,QK?Bn 'QK?B0+ 1+ 2+ 4 ai_ 7.8( mehadi _dmecogt annjcdaoe_ rdoc otke G REDβ mecekojmn ai_ ame _dmecogt kcjnkcjmtgaoe_ ]t oce fdiane acodqdot ja oce mecekojm jice acodqaoe_-Rcene P,QK?Bn cai ]e apmocem np]_dqd_e_ dioj oce BKN acodqaoe_ QK?Bn 'QK?B0+ 4+ 7( jm RED,acodqaoe_ QK?Bn 'QK?B1+ 2( ]ane_ ji ocedm otke G mecekojm kmeaemeice-Mice kcjnkcjmtgaoe_+ oce QK?Bn cai ajmh a ceoemjomdhemdc cjhkges rdoc oce Aj,QK?B 'QK?B3( ai_ omaingjcaoe oj oce ipcgepn-Rce G,QK?Bn aco an cjhkeododqe dicd]dojmn ja QK?B ja QK?B1 ca_ ij eaaeco 'Tdnnem eo ag-+ 1//0(-Küggemdai _pco meoeiodji aiagtndn can ]eei kemajmhe_ ji cji_dodjiag diacodqaodji hjpne hj_egn ocao diacodqaoe_ edocem QK?B0+ QK?B4 ai_ QK?B7 agjie jm di cjh]diaodjin di ?KFP199Ame eskmenndib ceggn 'Mmqdn eo ag-+ 1//7(-Rce apocjmn ncjre_ ocao eacc QK?B cai acodqaoe Küggemdai _pco mebmenndji ]po oj _daaemdib _ebmeen-Jjnn ja QK?B0 jm QK?B0.QK?B7 ca_ ij eaaeco ji Küggemdai _pco mebmenndji-Jjnn ja QK?B4 di ait cjh]diaodji menpgoe_ di a kamodag meoeiodji ja Küggemdai nompcopmen+ rcdge jigt a omdkge fijcf_jri 'QK?B0.4.7( ran a]ge oj capne cjhkgeoe meoeiodji ja oce Küggemdai _pcon 'Mmqdn eo ag-+ 1//7(-Rcene menpgon npbbeno ocao oceme esdno apicodjiag me_pi_aict ]eoreei oce ja ?KF+ oce hdce reme ctkjaemodge rdoc me_pce_ jqamdai qjgphe-?o 31 _atn kjnokamoph 'N31(+ hdce kjnnenne_ jigt aer ceagoct aiomag ajggdcgen+ hjno gdfegt aoomd]poe_ oj ai dicmeane di ajggdcpgam aomenda ai_ cjindnoeio rdoc oce eamgt ajggdcpgam escapnodji ja ?KF hpoaio hdce gdien-?__dodjiaggt+ aijocem ULR+ ULR6a dn eskmenne_ di oce Küggemdai ekdocegdph ai_ oce Uio6a ipgg hage hdce escd]do meoeiodji ja oce Küggemdai _pcon 'Namm % KcKacji+ 0887(-Rcdn jqemgak di eskmenndji ai_ kceijotke npbbeno a cjhhji kaocrat he_daoen ocedm eaaecon-ctkjbjia_dnh+ cai ]e capne_ ]t a _dnmpkodji ja cjmmeco hdbmaojmt ]ecaqdjpm ja EiPF iepmjin-?gocjpbc ocdn hdbmaojmt ]ecaqdjpm ran didodaggt _encmd]e_ aghjno 2/ teamn abj+ a cjhkmeceindqe kmjcenndib kmeqeioe_ BL? esomacodji ajm jocem canen-HbOUS (8H or GL) CcmPSr oT apSQWmSna OnOlgaSR heocaijg '0//% ordce+ 7/%+ 4/%( ai_ rance_ di 0sNBQ ajm 0cm-Qahkgen reme feko ao 3yA 8roen rcmp lSnUbV :fpSrWmSnb (mm) ajm apmocem kmjcenndib-Rcmjpbcjpo cdnojmt+ oce _endme ja ncdeiodnon oj pi_emnoai_ kctndjgjbt ai_ _dneane ]t ocjmjpbcgt nop_tdib aiaojhdcag aeaopmen+ can agratn aace_ ai diomacoa]ge gdhdoaodji9 ocet caiijo ndhkgt nee ocmjpbc oce odnnpe-Bdnnecodji can ocemeajme ]eei oce hj_pn jkemai_d ja aiaojhdnon9 amjh _encmdkodji ai_ aiaojhdcag hakkdib ja ocene ceggn di cphai eh]mtjgjbt+ rceocem _pe oj njcdjcpgopmag+ megdbdjpn jm hjmag meanjin+ mehadin gacfdib-Apmmeiogt+ akkmjsdhaoegt jigt 4/% IOPlS -( HcmOn aSf RSbSrmWnObWon E8G prWmSra AQ 05 'EU 4-4( 0 GFA.EiPF cegg 7 lpaiodadcaodji 8H6EI:G / HSf RSbSrmWnObWon E8G prWmSra AQ 06 'EU 5( 1 GFA.EiPF cegg /(1(-LVolS-mocnb WmmcnoabOWnWnU 00,02 lpaiodadcaodji ?dhn % M]eecodqen Eagei'n kdjieemdib nop_den+ oj hj_emi _at ]djgjbdnon rcj mjpodiegt necodji odnnpen oj ga]eg nompcopmen ajm hdcmjncjkdc aiagtndn-Ucdgno ocene heocj_n caqe diajmhe_ a reagoc ja fijrge_be gdifdib aiaojhdcag ajmh oj ja cgdidcag AFF canen caqe eskgadie_ beieodc capnen+ rdoc oce mehadidib kmjkjmodji aoomd]poe_ oj pifijri beieodc hpoaodjin-Rce fet adhn ja ocdn rjmf ame ocemeajme oj9 Kaoemdagn % Keocj_n 4',?EAE?RE?RR?A?ERAA?EA,2' QPW neine 4',AAR?A?EARRRERAA?EREE,2' QPW aiodneine 4', AEEE?EEE?R?A?EE?AR???A,2' DED05 neine 4', ARER?EER?EA?RAREREEA,2' AQ 07 'EU 5( 0 GFA.EiPF cegg Qahkgen reme kemhea]dgdne_ ai_ ]gjcfe_ ]t mjoaodji ao 6/ mkh di 0VNBQ cjioadidib /-1% 04 lpaiodadcaodji AQ 08 'EU 6( 0 begaodi 'Nmjga]j(+ ai_ /-4% Rmdoji V,0// 'Qdbha,?g_mdcc( 'NBQER( ao PR 'Begge eo ag-+ 1/03(-GFA.GQF.EiPF cegg 06 lpaiodadcaodji Djm dhhpijnoadidib+ nahkgen reme omainaemme_ oj a njgpodji cjioadidib /-0% nakjidi DED05 aiodneine 4',A?EEAA?REA?A?E?E?E??,2' QPW1 neine AQ 12 'EU 7( 1 GFA.EiPF cegg 14,17 lpaiodadcaodji '0/hb.hJ( di NBQER ojbeocem rdoc oce kmdhamt aiod]j_den 'IOPlS 1( ai_ kgace_ ao 26yA
	QK?Bn di mebpgaodib ?KF he_daoe_ eaaecon ji oce Küggemdai _pcon-_pmdib oce admno omdhenoem ja benoaodji EU 00 1 34,36 -(2(, Con-8OnonWQOl HWUnOllWnU EObVeOga C03 mao pmjbeidoag md_ben cpgopme_ rdoc ?KF ajm 13 cjpmn es qdqj ncjre_ a ctojkganhdc lpaiodadcaodji GFA.EiPF cegg apicodji+ ocet ame dicemeiogt agare_ _pe oj a 2,Bdheindjiag akkmecdaodji ja nompcopmen ]edib oj ccamacoemdne oce _eqegjkheio ja cphai pmjbeidoag ai_ kemdkcemag iemqjpn ntnoehn 4',?AEA?RRA?RAEREREERAR,2' QPW2 neine 4',??AREA??RRARRAEEA?EA,2' QPW2 aiodneine EU 0/ 1 lpaiodadcaodji 27,3/ GFA.EiPF cegg , akkgt meceio a_qaicen di oce adeg_ ja odnnpe cgeamdib ai_ rcjge hjpio dhhpijnoadidib 4',EER??EREEAAR?EAREERE,2' QPW1 aiodneine EU 8 2 18,21 GFA.EiPF cegg lpaiodadcaodji 'Beicchamf+ Gicp,Qcafem Kdid(+ rdoc mjoaodji ao 6/ mkh+ ajm 6 oj 03 _atn _ekei_dib ji odnnpe
	, pne ocene oeccidlpen di cjh]diaodji rdoc oma_dodjiag cdnojgjbdcag heocj_n oj kmjqd_e oce Ch]mtjn ai_ ajeopnen reme adse_ ]t dhhemndji di 3% ND? ao 3yA jqemidbco jm ajm 2,4 _atn EU 01 0 GFA.EiPF cegg 4/ lpaiodadcaodji
	admno _eoadge_ _encmdkodji ja EiPF hdbmaodji di cphai _eqegjkheio ai_ oj cmeaoe a 2B _ekei_dib ji nahkge ndue-Rce odnnpen reme cmtjkmjoecoe_ di 2/% npcmjne.NBQ ao 3yA AQ 08 'EU 6( 0 07 GFA.2BGQAM.JQK
	aogan ja ocedm nkaodag _dnomd]podji _pmdib eamgt _eqegjkheio jqemidbco+ eh]e__e_ di Rdnnpe,Ref MAR cjhkjpi_ 'Qafpma Ddieoef+ SQ?(+ amjuei di _mt dce AQ 10 'EU 6-4( 0 11 GFA.2BGQAM.JQK
	, ccamacoemdne a kjoeiodag mjge ja ?iod,Küggemdai cjmhjie ndbiaggdib di oce _eqegjkheio ai_ nojme_ ao ,7/yA piodg necodjidib-Dmjuei nahkgen reme cpo nemdaggt pndib a Jedca AK 2/4/Q EU 8 0 18 GFA.2BGQAM.JQK
	ja oce EiPF ntnoeh ai_ don kjoeiodag cjiomd]podji oj AFF cmtjnoao 'Jedca Bdjntnoehn Lpnngjcc Eh]F+ Eemhait(-Rce necodjin reme ocar,hjpioe_ jioj EU 8 0 20 GFA.dBGQAM.JQK
	bgann ngd_en ai_ ocei+ nojme_ ao ,7/yA piodg kmjcenndib-Djpm nemden ja necodjin reme beiemaoe_ EU 8 1 2/ 2B Pecjinompcodji
	Udocjpo a bjj_ pi_emnoai_dib ja kctndjgjbdcag _eqegjkheio+ re gacf oce api_aheioag ajm AQ05+ adqe ajm AQ06+ AQ07 ai_ AQ08+ ai_ nds ajm jg_em eh]mtjn ai_ ajeopnen-Rce ocdcfienn EU 01 1 4/,44 2B Pecjinompcodji
	-(2( InbrOQSllclOr HWUnOllWnU EObVeOga 4&,ERAR,2 &ai_ don 4&,?E?A,2& cjhkgeheioamt nelpeice rdocdi oce kmjhjojm mebdji-Rce kcjnkcjmtgaodji di menkjine oj REDβ cai qamt+ rdoc keaf acodqaodji jccpmmdib amjh hdipoen+ fijrge_be melpdme_ ajm cgdidcdain ai_ meneamccemn oj oacfge _eqegjkheioag nti_mjhen ocao diagdco ja oce necodji ran 1/µh ajm eacc nahkge-IobOl ncmPSr ,-
	QBC _dnkgatn njhe _ebmee ja ojgemaice cjreqem+ rdoc np]nodopodjin ja oce necji_ ipcgejod_e ja oj cjpmn aaoem nodhpgaodji 'Mgnnji eo ag-+ 1//0(-a neqeme ceagoccame ai_ ehjodjiag ]pm_ei pkji njcdeot-Peceio a_qaicen di iji,diqandqe+ di Djm rcjge,hjpio noadidib ai_ 2BGQAM cgeamdib+ nahkgen reme rance_ di dce,cjg_ NBQ ao geano
	Aj,dhhpijkmecdkdoaodji nop_den caqe ncjri ocao BKNP0] dioemacon di a gdbai_,_ekei_eio haiiem rdoc ?KFP1 'Ejpé_am_ eo ag-+ 1///: meqdere_ ]t Hjnnj eo ag-+ 1//0(--(2(1 GHB69a Rce cganndcag diomaceggpgam ndbiaggdib kaocrat ja oce REDβ aahdgt dn oce QK?B kaocrat ai_ dn oce 4&,ERAR,2& nelpeice ncjri ijo oj dioemaeme rdoc QK?B ]di_dib 'Qcd eo ag-+ 0887(-Qeqemag jocem heccaidnhn caqe ]eei _encmd]e_+ cjreqem+ dicgp_dib ]di_dib oj jocem qdqj dhabdib oeccidlpen+ caqe ncjri bmeao kmjhdne di _eoecodib cjibeidoag a]ijmhagdoden an 1 odhen ajm 1/ hdi-Leso+ ocet reme adse_ ]t dhhemndji di 3% kamaajmhag_ect_e 'ND?( ao 3yA Rce caijidcag kaocrat ja ULR ndbiaggdib di_pcen ai accphpgaodji ja β,caoeidi di oce ctojkganh ai_ don omaingjcaodji di oce ipcgepn-β,caoeidi acon an a cj,acodqaojm ja oce fB kaocrat cai ]e acodqaoe_ ]t a qamdeot ja esomaceggpgam cpen+ rdoc ?KF ]edib epno jie-regg an kmjqd_dib diajmhaodji ji bmjnn ojkjgjbdcag aeaopmen ja ajeoag _eqegjkheio: cjreqem+ ajm 13c ajm EU 5,7 eh]mtjn+ 2 _atn ajm 8 EU ajeopnen+ ai_ 4 _atn ajm EU 0/,01 ajeopnen-/(1(, 7lSOQVWnU
	?KFP1.BKNP0] dioemacodji can ]eei ncjri oj acodqaoe oce QK?B0 kaocrat di ]joc a cjhhji aeaopme ja ocdn npkemaahdgt-Rcdn dn ]ecapne oce otke G mecekojmn ame a]ge oj _dmecogt omaincmdkodji aacojmn ocmjpbc kmjoedi,kmjoedi dioemacodjin+ mecmpdoheio ja omaincmdkodjiag cj, omaincmdkodji aacojmn ja oce RAD . JCD aahdgt-Gi oce a]neice ja nodhpgaodji ]t ULR kmjoedin+ ?_hdidnomaodji ja ?KF oj hdce di_pcen acodqaodji ja oce LD,fB kaocrat ai_ eskmenndji ja ocet gacf npaadcdeio menjgpodji di jm_em oj diajmh _eqegjkheioag ]djgjbdnon ja cpmmeiogt pifijri ?aoem adsaodji nahkgen reme nojme_ ao 3yA di 0sNBQ cjioadidib /-/0% nj_dph aud_e piodg pne-Rj mehjqe kdbheioaodji ai_ me_pce ndbiag,oj,ijdne maodj megaoe_ oj cehaojhan+ oce odnnpe
	aeaopmen ja jmbaijbeiendn-Rcdn can meceiogt ]eei hjno nomdfdibgt cdbcgdbcoe_ ]t oce npmbe di ]geaccdib ran cammde_ jpo 'Peidem eo ag-+ 1/03(-Rce nahkgen reme _ect_maoe_ ajm 0cm ao PR di
	Xdfa qdmpn diaecodjin ai_ mekjmon ja don _eomdheioag eaaecon ji cekcagdc _eqegjkheio-ancei_dib cjiceiomaodjin ja heocaijg di 0sNBQ '4/%+ 7/%+ 0//%(-Rce nahkgen reme ocei
	omeaoe_ jqemidbco ao 3yA rdoc a 5% ct_mjbei kemjsd_e njgpodji di 0//% heocaijg-Rce

QK?R,0 '_emdqe_ amjh dhhaopme Qemojgd ceggn ]t oambeoe_ jicjbeiendn( ai_ K?,0/ '_emdqe_ amjh a hjpne Jet_db cegg ophjpm( cegg gdien 'Hjnnj eo ag-+ 1//0(+ agocjpbc do can agnj ]eei ncjri oj aco an a iebaodqe mebpgaojm ja diomaceggpgam ndbiaggdib 'Begqdgge eo ag-+ 1//4

dn pi_eoecoa]ge di oce eh]mtjidc bjia_n ja ]joc nesen+ do dn mea_dgt _eoecoa]ge di oce kjnoiaoag jqamt rceme do dn eskmenne_ ]t jjctoen ja nhagg aiomag ajggdcgen ai_ bmaipgjna ceggn ja gambe aiomag ajggdcgen 'Wd eo ag-+ 1//0(-Gi jie ja oce aer nop_den oj esahdie ?KF ndbiaggdib di iepmjin+ Je]epmmdem ai_ cjggeabpen '1//7( _ehjinomaoe_ ocao oce kmj,npmqdqag eaaecon ja ?KF reme he_daoe_ qda BKNP0] ]t mebpgaodib oce npmqdqag aacojm iepmjnemkdi-BKNP0] can agnj ncjri oj he_daoe oce hdbmaodji ja heneiccthag cegg abbmebaoen di ccdcf eh]mtjn di qdomj+ kjnnd]gt ]t kmjhjodib oce eskmenndji ja esomaceggpgam haomds kmjoedin 'Giad eo ag-+ 1//6(-Bpmdib seijkpn eh]mtjbeiendn BKNP0] dn nomjibgt eskmenne_ di oce ]madi+ ai_ hdbmaodib iepmag cmeno ceggn 'Qccdgge eo ag-+ 1/05(-omain_pce esomaceggpgam cpen ]t kcjnkcjmtgaodib mecekojm annjcdaoe_ QK?B hjgecpgen ocao np]nelpeiogt _dnnjcdaoe amjh oce mecekojm ai_ omaingjcaoe oj oce ipcgepn-Udocdi oce QK?B aahdgt oceme ame edbco _dnodico QK?B kmjoedin+ cjhkmdndib ocmee apicodjiag cgannen9 mecekojm ndbiaggdib ]t ]di_dib oj ai_ nelpenoemdib acodqaoe_ otke G mecekojmn jm P,QK?Bn+ ocpn kmeqeiodib ndbiag omain_pcodji-G,QK?Bn ame jaoei pkmebpgaoe_ ]t oce nkecdadc kaocratn ocao ocet dicd]do+ ocpn kmjqd_dib a iebaodqe aee_]acf heccaidnh -einpmdib ocao oce habidop_e ai_ _pmaodji ja oce menkjine cjmmegaoen rdoc oce cjiodipdib kmeneice ja oce esomaceggpgam gdbai_ 'Lafaj eo ag-+ 0886(-Rcdn dn agnj oce cane rdoc ?KF+ an 1 cjpmn omeaoheio ja Jet_db _emdqe_ dhhjmoagdne_ cegg gdien capne_ ai dicmeane di QK?B5 ai_ QK?B6 acodqdot+ rdoc acodqdot keafdib ao 5 cjpmn 'eamgdeno acodqaodji _eoecoe_ ]t Ljmocemi aiagtndn ran ao 8/ hdipoen ajggjrdib ?KF omeaoheio( 'Agamfe eo ag-+ 1//0(-?ccphpgaodji ja QK?B cjhkgesen rdocdi oce ipcgepn menpgon di omaincmdkodjiag menkjinen oj agoem beie eskmenndji-Rce ndhkgeno ja rcdcc dn _dmeco BL? ]di_dib+ rceme QK?Bn apicodji an omaincmdkodji acodqaojmn 'Umaia+ 1///(-Rcdn otkdcaggt jccpmn qda a QK?B ]di_dib egeheio 'QBC( acodqaojmn jm cj,mekmennjmn+ ]gjcfdib jm cjhkeodib rdoc jocem omaincmdkodji aacojmn ai_ adiaggt+ dicmeandib oce _ebma_aodji maoe ja jocem omaincmdkodjiag mekmennjmn 'meqdere_ ]t Umaia+ 1///(-Ucdge oce QK?B diomaceggpgam ndbiaggdib kaocrat dn a p]dlpdojpn aeaopme ja REDβ aahdgt ndbiaggdib+ a iph]em ja QK?B di_ekei_eio canca_en ocao jkemaoe di a cjioeso,_ekei_eio haiiem ame menkjind]ge ajm iph]em ja cegg,nkecdadc menkjinen-Rcdn can ]eei ctkjocendne_ oj jccpm an REDβ mecekojm cjhkgesen caqe ]eei mekjmoe_ oj escd]do _pag nkecdadcdot+ kcjnkcjmtgaodib otmjndie mend_pen 'meqdere_ ]t Xcaib+ 1//8(-Djm dinoaice+ di ekdocegdag ceggn+ REDβ can ]eei ncjri oj acodqaoe oce hdojbei,acodqaoe_ kmjoedi fdiane 'K?NI( kaocrat ]t di_pcdib oce acodqaodji ja K?NI fdiane fdiane 'K?N2I6( qda RP?D5 'Qjmmeiodij eo ag-+ 1//7: Wahancdoa eo ag-+ 1//7(-Rce fdieodcn ja Csomaceggpgam ndbiag-mebpgaoe_ fdiane 'CPI( oce haejmdot ja oce ctojkganhdc β,caoeidi kjjg dn feko diacodqe ]t a _enompcodji cjhkges ocao cjinodopodqegt kcjnkcjmtgaoen oce β,caoeidi rcdcc rdgg ]e oambeoe_ ]t p]dlpdodi gdbane C2 'βRmAN( ai_ eamhamfe_ ajm kmjoeanjhe _ebma_aodji 'meqdere_ ]t Ageqemn % Lpnne+ 1/01(-accphpgaodji ja β,caoeidi di kemd,Küggemdai heneiccthag ceggn+ rcdcc ran a]neio di piomeaoe_ nahkgen '?ggam_ eo ag-+ 1///(-Qp]nelpeio eskemdheion _eoemhdie_ oce ipcgeam omaingjcaodji ja β,caoeidi oj ]e capne_ ]t JCD0+ ai_ diqjgqe_ di oce akjkojndn ja oce heneiccthag gatem kmece_dib oce ekdocegdjheneiccthag omaindodji ocao dn enneiodag ajm oce mebmenndji ja oce Küggemdai _pco-Lpcgeam aacojm κ,gdbco,ccadi,eicaicem ja acodqaoe_ B ceggn 'LD,κB( dn a kmjoedi ocao dn kamo ja oce npkemaahdgt ja omaincmdkodji aacojmn-Go can ]eei kmeqdjpngt dhkgdcaoe_ di a rd_e maibe ja ceggpgam kmjcennen dicgp_dib9 oce dhhpie menkjine+ oce menkjine oj nomenn+ ai_ akjkojndn-LD, fB dn a ctojkganhdc kmjoedi cjhkjne_ ja orj np]pidon9 k4/ ai_ k54 'Peg?( ai_ dn ceg_ di ai diacodqe noaoe ]t ]di_dib oj oce GfB kmjoedi-Rce GII fdiane kcjnkcjmtgaoen GfB di menkjine oj esomaceggpgam ndbiagn+ kemhdoodib oce megeane ja LD,fB dioj oce ctojkganh-Jd]emaoe_ LD,fB omaingjcaoen oj oce ipcgepn rceme do mebpgaoen oambeo beien 'Edghjme 1//5( ';WUcrS -,(-Rce La, oce Ges0 beie di oce hahhamt bgai_ 'Qebeq eo ag-+ 1//0( ai_ oce kmjnoaoe 'Qebeq eo ag-1//0(-Qdhdgamgt+ nodhpgaodji rdoc ?KF can ncjri ocao ntiembdnodc acodqaodji ja LD,fB ai_ QK?B0 ca_ aiod,kmjgdaemaodqe eaaecon di ]meano caicem ceggn 'Epkoa eo ag-+ 1//6(-8H6EI:G . gjno-Rcdn can ]eei enkecdaggt kmj]gehaodc ajm oce nop_t ja _eqegjkheioag kmjcennen+ rceme nompcopmen ame cjiodipaggt eqjgqdib+ ai_ ocemeajme a kmecdne qdnpagdnaodji can ]eei dhkjnnd]ge oj accdeqe ocmjpbc oma_dodjiag heocj_n ai_ aiaojhdcag aoganen-Dpmocem oj ocdn+ a haejmdot ja jpm fijrge_be ja _eqegjkheioag ntnoehn amdnen amjh nop_den di ccdcfei ai_ ue]maadnc: rcdcc+ agocjpbc esceggeio hj_egn di rcdcc oj nop_t ocene kmjcennen+ hat kjnnenn ndbidadcaio _daaemeicen amjh cphain-Ajpkge_ rdoc oce _daadcpgoden di odnnpe accenn+ jpm pi_emnoai_dib ja cphai _eqegjkheio can kmjbmenne_ kemcakn oce ngjreno ja ait ]djgjbdcag kmjcenn ndice oce 082/'n: rcdgno di njhe canen j]nemqaodjin amjh gjrem qemoe]maoen caqe ]eei emmjiejpngt akkgde_ oj cphain menpgodib di noamf cjioma_dcodjin di oce esoaio gdoemaopme-Rce iph]em ja eh]mtjn.ajeopnen aiagtne_+ oce Amjri,Pphk geiboc meaemme_ oj ocene nkecdhein ai_ oce otke ja kmjcenndib ame gdnoe_ di IOPlS .-ndue ai_ _eindot-Rcdn ran ajggjre_ ]t nds rancen ja 2/ hdi di NBQER ao PR-Leso+ necji_amt aiod]j_den 'IOPlS 2( reme _dgpoe_ 094// di a njgpodji cjioadidib /-0% nakjidi '0/hb.hg( di NBQER ai_ kanne_ ocmjpbc a /-11µh adgoem-Qahkgen reme dicp]aoe_ ao 26yA 'Beicchamf+ Gicp,Qcafem Kdid( di oce necji_amt aiod]j_t njgpodji jqemidbco jm ajm 1 _atn _ekei_dib ji nahkge ndue ai_ _eindot-?aoem nds rancen ja 2/ hdin di NBQER ao PR+ nahkgen reme nojme_ di oce _amf ao 3yA di piodg odnnpe cgeamdib-Rce kmjojcjg ran ndhdgam ajm ndibge ai_ hpgodkge ga]eggdib-/(

1(. -9IH8D

  Rrj ajmhn ja EiPF ame kmeneio di oce cphai ]madi-Kahhagdai EiPF 'EiPF,G( mebpgaoen oce mekmj_pcodqe asdn+ rcemean oce apicodji ja EiPF,GG+ jmdbdiaggt dnjgaoe_ amjh oce ccdcfei ctkjocagahpn 'cEiPF,GG( 60+ dn gambegt pifijri-Gi jm_em oj qemdat ocao oce hdbmaojmt EiPF iepmjin re j]nemqe_ di_ee_ eskmenne_ EiPF,G+ eacc aiodnemph ran kmea_njm]e_ ajm 13 cjpmn ao 3yA rdoc oce hahhagdai EiPF,G 'EeieApno+ Jpseh]pmb( ao 4μb.hg ]eajme akkgdcaodji+ rcdcc cjhkgeoegt egdhdiaoe_ EiPF dhhpijmeacodqdot di oce ianag mebdji ai_ ]madi ja AQ 07 eh]mtjn ';WUcrS -.(-Fjreqem+ cdbc nelpeice cjhjgjbt ]eoreei oce EiPF,G ai_ EiPF,GG _ecakekod_en 'jigt 2 ahdij acd_ np]nodopodjin( cjpg_ aggjr EiPF,G aiod]j_den oj cmjnn,meaco

	EU 8,0/+ EU 00,01( reme cjhkame_ ]t jie,rat ?LMT? ajggjre_ ]t Bjiaemmjid'n kjno
	cjc aiagtndn oeno-
	Qemdag cjmjiag necodjin '1/μh( amjh eh]mtjn ai_ ajeopnen reme cpo ai_ ga]egge_ ajm EiPF an
	_encmd]e_ a]jqe-Djpm nemdag nemden reme beiemaoe_ ajm AQ05 'i < 0(+ adqe nemdag nemden reme
	beiemaoe_ ajm AQ06,AQ08 'AQ06,07+ i < 2(+ nds nemden ajm jg_em eh]mtjn ai_ ajeopnen reme
	Djm agg odnnpe cgeamdib+ a hj_dade_ 2BGQAM cgeamdib kmjojcjg ran pne_-?gg dicp]aodji noekn reme beiemaoe_ 'AQ08,12+ i < 2: EU 8,0/+ i < 4: EU 00,01+ i < 2(-EiPF,dhhpijnoadie_
	kemajmhe_ di _amf cji_dodjin ao PR di a aphe cjj_+ ji a op]e mjoaojm 'QB2+ Qopamo( ao 03 mkh+ necodjin reme esahdie_ pndib ai ?sdj Ghabem-X0 ?kjRjhe hdcmjncjke 'Xednn+ Eemhait(+
	pndib a 04 hg ceiomdapbe op]e 'RNN+ Bponccem(-Qahkgen reme admno _ect_maoe_ di ancei_dib elpdkke_ rdoc a hjojmdne_ noabe ai_ ai ?sdjAah Kmh cahema 'Xednn+ Eemhait(-Rj qdnpagdne
	cjiceiomaodjin '4/%+ 7/%+ ai_ 0//%( ja oeomact_mjagpmaie 'RFD: aict_mjpn+ cjioadidib 14/ ai_ cjpio oce ceggn a Xednn 1/s j]eecodqe 'L? /-7( ran pne_-EiPF iepmjin reme cjpioe_ eqemt
	kkh ]potgaoe_ ct_mjstg,]pojgpeie dicd]dojm+ Qdbha,?g_mdcc( _dgpoe_ di F 1 M-Rce didodag 4/% 7/μh nkaiidib oce eiodme cea_ ja eh]mtjn ai_ ajeopnen-Rjoag iph]emn ja EiPF ceggn reme
	RFD ranc ran kemajmhe_ jqemidbco rcdge oce 7/% ai_ 0//% RFD dicp]aodjin reme geao ajm cagcpgaoe_ di eacc nahkge ai_ cjh]die_ oj bdqe bmjpk heain ± QCK ?gg aiagtnen reme
	0c2/ eacc-Qahkgen ieso pi_emreio a _egdkd_aodji noek ja 2/ hdi di _dccgjmjheocaie 'BAK: kemajmhe_ pndib Nmdnh 4 'EmakcNa_ Qjaorame( ai_ annenne_ ajm ijmhagdot 'Qcakdmj,Udgf oeno(
	AQ06,07+ AQ08,12+

Qdbha,?g_mdcc( ajggjre_ ]t ai jqemidbco cgeamdib noek di _d]eiutgeocem 'BBC: Qdbha,?g_mdcc(-Rce ieso _at+ nahkgen reme nojme_ di di_dqd_pag gdbco,a]njm]dib bgann qdagn 'Pjodga]j+ Pjoc( ao /(1(3 HpSQWTWQWbg bSaba rdoc EiPF,GG-Ue ocemeajme kemajmhe_ agpjmenceio di ndop ct]md_duaodji 'DGQF( eskemdheion pndib a cPL? kmj]e _dmecoe_ abadino EiPF,G hPL? '_encmd]e_ ]egjr(+ rceme gacf ja ndbidadcaio ipcgejod_e nelpeice cjhjgjbt rjpg_ mpge jpo oce cmjnn,meacodji ja oce EiPF,G kmj]e rdoc EiPF,GG hPL?-Rcene eskemdheion cjiadmhe_ ocao oce hdbmaojmt EiPF iepmjin di cphain eskmenne_ EiPF,G ';WUcrS -.(-/(1(1* GnGH QSll QocnbWnU ai_ qamdaice+ rcei akkmjkmdaoe-Qahkge nduen reme ccjnei accjm_dib oj oce noai_am_ kmacodce di oce adeg_-Baoa ajm EiPF cegg iph]em ]eoreei oce ajpm bmjpkn aiagtne_ '

CSe boola bo SfplorS VcmOn RSdSlopmSnb

  (,( reme meqemne omaincmd]e_ pndib QpkemQcmdko x GGG Peqemne Rmaincmdkoane 'Jdae Reccijgjbden+ Aamgn]a_ A?+ SQ?(-Peag,odhe NAP ran cammde_ jpo ji ?kkgde_ Bdjntnoehn 68//FR Dano Peag,Rdhe NAP Qtnoeh pndib esji,

	IOPlS 1( ErWmOrg OnbWaSrO 0(1		6rbWQlS 1
	6nbWUSn	Hoab apSQWSa	HocrQS	9WlcbWon
	?KF		Kjpne	?]cah+ ?]13431	094//
	?KF ?KFP1 L? IrWRWmSnaWonOl KWacOlWaObWon OnR 6nOlgaWa oT :Orlg HcmOn 9SdSlopmSnb Pa]]do ?]cah+ a]0/2122 094// Ejao P%B ntnoeh+ ?D0507 091// 8H6EI:G 0
	?KFP1 nkai,nkecdadc RalKai x Eeie Cskmenndji ?nnatn '?kkgde_ Bdjntnoehn+ Aamgn]a_ A?+ SQ?(-Pa]]do A?QJM+ 45E 091/// EiPF Pa]]do Nmja-E-Rmahp+ Sidqemndot ja Bjm_eaps+ Dmaice 092/// Agamdatdib cphai _eqegjkheio pndib 2B dhabdib Kjmbaie Begge+ Baqd_ Ej_eamjt+ Eémam_ Ajpgt+ Qahpeg ?-Kagjie+ Dmaicdn ?KFP1 'Kh//402736[h0(: ?cqP0 'Kh/0220/58[h0(: BKNP0a 'Kh//36654/[h0(: BKNP0] 'Kh/2/12860[h0(-Ajiomjg cjpnefeekdib beien9 Pi07n 'Fn888888/0,n0( ai_ ?co] EiPF Pa]]do JP4+ Bm-P-Beijdo+ Kjioméag Eeiemag Fjnkdoag+ Kjioméag+ Opé]ec+ Aaia_a 090/// ja omainkameio rcjge eh]mtjn Ajggdem+ Najgj Edacj]did ai_ ?gadi Acé_joag
	Bm-Cmdf Fma]jqnuft+ Ginodopoe ja 'Kh//5/6828(-?hkemane acodqaodji ran accdeqe_ ]t ceaodib oj 4/yA ajm 1hdin+ ]eajme EiPF Epdiea,Ndb Cskemdheioag Ke_dcdie ja oce Fpibamdai 090////
	_eioaopmdib ao 84yA ajm 1/n+ ajggjre_ ]t 3/ ctcgen ja 0n 84yA rdoc a 1/ n esoeindji odhe ao ?ca_eht ja Qcdeicen+ Bp_akeno+ Fpibamt Np]gdnce_ di Aegg
	Nemdkcemdi 5/yA-Eeie eskmenndji _aoa reme aiagtne_ pndib QBQ 1-3-0 ai_ Baoa ?nndno 2-/-0 njaorame Pa]]do Kdggdkjme+ ?B042/ 090/// R?E,0 Ejao P%B ntnoeh ?D1104 094// Tjgphe 058+ Gnnpe 0+ kk050,062-e01 '1/06(
	'?kkgde_ Bdjntnoehn+ Aamgn]a_ A?+ SQ?(-Bjp]gecjmodi 'BAV( Ejao	Qaioa Ampu+ QA,7/55	094//
	/(-(. FcOlWbObWdS E8G β,GGG op]pgdi 'RSH0( Kjpne	Qdbha+ R755/	097//
	BLCP Djggjrdib lPR,NAP+ kmdhem kmj_pcon reme mpi ao a cjinoaio 01/T ji a 1% abamjne beg rdoc Ejao P%B ntnoeh+ ?D1143 091// N?V5 Pa]]do Kdggdkjme+ ?B1126 093//
	QWBP™ bjg_ 'RcemhjDdncem Qcdeiodadc+ SQ?( ai_ ]ai_n qdnpagdne_ pndib ai pgomaqdjgeo FpAB Kjpne Jdae Reccijgjbden ?10160 091//
	omaindggphdiaojm-Id56		Pa]]do	?]cah+ a]0447/	091//
	QMV1		Ejao	Qaioa Ampu+ nc,0621/	092//
	QMV0/ /(-(/ LSabSrn 7lob ?N,1 agkca	Ejao Ejao	L,1/: Qaioa Ampu: nc,06231 2B4 npkemiaoaio 092: BQFB	091// 091//
	Apgopme kgaoen reme amjuei an _encmd]e_ a]jqe+ lpdcfgt ocare_ ai_ kmjoedi dhhe_daoegt Lepmjkdgdi,1 'Lmk,1( Ejao P%B ntnoeh ?D1104 093//
	esomacoe_ rdoc 4//μg ja amencgt kmekame_ gtndn ]paaem Y14hK Rmdn kF 6-3+ 4/hK β, Ac?R Ejao Kdggdkjme: ?B033N 094//
	bgtcemjkcjnkcaoe+ 0% Rmdoji s0//+ 0-4hK CER?+ /-4hK CBR?+ 0hK nj_dph Ktjndi Feaqt Acadi Kjpne Kdggdkjme+ /4,605 090///
	jmocjqaia_aoe+ 0/μb.hg Jepkekodi ai_ Neknoaodi ?+ 0/μb.hg akmjodidi+ 0//μb.hg NKQD N?V1 Ejao P%B ntnoeh ?D2253 090///
	NJT?N 'meabeion njpmce_ amjh Qdbha ?g_mdcc+ Qo-Jjpdn KM+ SQ?(Z-Nmjoedi esomacon reme ocei Kjpne ?]cah a]70608 094// ?codi Kjpne Qdbha ?g_mdcc: ?4205 090///
	cjhjbeidne_ pndib a 15 bapbe iee_ge ]eajme ceiomdapbdib ao 01+///b ajm 04 hdin ao 3yA-Rce N,CPI0.1 Pa]]do Aegg Qdbiaggdib: 80/0J 090/// 'Rcm1/1.Rtm1/3( npkemiaoaio ran mecjqeme_ ai_ kmjoedi lpaiodade_ pndib oce Bma_ajm_ heocj_ 'BdjPa_+ CPI0.1 Pa]]do Aegg Qdbiaggdib: 80/1J 090///
	Femcpgen+ A?(-0s nahkge ai_ 0s gja_dib ]paaem 'Giqdomjbei+ Aamgn]a_ A?+ SQ?( ran a__e_ oj
	06/

oce nahkgen+ rcdcc reme ocei ]jdge_ ajm 4 hdi ]eajme egecomjkcjmendn ao 01/T ajm 0// hdin di 3-01% omdn,aceoaoe kmecano QBQ,kjgtacmtgahd_e begn accjm_dib oj oce kmjojcjg npkkgde_ rdoc oce LpN?EC ntnoeh 'Giqdomjbei+ Aamgn]a_ A?+ SQ?(-?aoem ndue amacodjiaodji+ oce kmjoedin reme

;ormObWon oT bVS olTOQborg plOQoRS OnR KCD

  Ue ieso aiagtne_ oce _eqegjkheio ja oce TLM ao np]nelpeio eh]mtjidc noaben 'AQ 07,1/+ akkmjs-33 oj 38 _atn ja benoaodji(-Ue reme a]ge oj d_eiodat nthheomdcag ]eai,ncake_ TLMn+ gjcaoe_ ao oce ]ane ja oce ianag nekoph+ di agg eh]mtjn 'AQ

	Development of the male urogenital system
	beidoag _pcon akkeam hjmkcjgjbdcaggt ndhdgam di ]joc nesen rdoc orj kadme_ nompcopmen9 oce Ujgaadai _pcon 'UB( rcdcc _emdqe amjh oce henjiekcmjn ai_ oce Küggemdai _pcon 'KB(-Rcdn fijrge_be dn kmdhamdgt ]ane_ ji cdnojgjbdcag ai_ egecomji hdcmjncjkt aiagtndn 'Dmdoncc eo omdhenoem ja benoaodji ';WUcrS .-Q5 ;WUcrS ..U(-cphai pmjbeidoag ntnoeh ran nop_de_ pndib aiod]j_den abadino oce Nas1 omaincmdkodji aacojm an Beqegjkheio ja oce EiPF ntnoeh di Fphain ]ecaqdjpm 'Bpgac % Rjmeggj+ 1//2(-cap_aggt+ rceme do hadioadie_ cjioaco rdoc oce jgaacojmt ekdocegdph ocmjpbcjpo oce admno cphain pigdfe di hdce 'Eejmban eo ag-+ 1/04: Jdooge eo ag-+ 1//6(-Feme oce _eqegjkheio ja oce oce _eoecodji ja kcemjhjien , kmdhamdgt iji,qjgaodge ndbiagn megaoe_ oj njcdag ai_ mekmj_pcodqe ran cgjne_ ai_ aghjno cjhkgeoegt nekamaoe_ amjh oce ianag caqdot ';WUcrS .-O-P( esceko ag-+ 1/01: Fancdhjoj+ 1//2(+ ai_ can ijo teo ]eei nop_de_ ao a ceggpgam ai_ hjgecpgam geqeg di 8H6EI:G 1 1(1 Kjno qemoe]maoen kjnnenn orj aiaojhdcaggt _dnodico jgaacojmt ntnoehn9 oce hadi jgaacojmt ntnoeh+ menkjind]ge ajm oce _eoecodji ja qjgaodge j_jmaion+ ai_ oce qjhemjianag ntnoeh+ rcdcc he_daoen oemmdojmden ';WUcrS ., O-Q(-05,12+ i < 6: ;WUcrSa .--..( ai_ ajeopnen 'EU 8,01: i < 7( aiagtne_-Bt AQ 07+ oce TLM ;WUcrS .,
	Nas1 hPL? ran kmeqdjpngt _eoecoe_ di oce henjiekcmjn ai_ UB ao 5,6 benoaodjiag reefn Gi agg qemoe]maoen nop_de_ nj aam+ oce _daaemeiodaodji ja EiPF iepmjin 'd-e oce eskmenndji ja
	'Reggdem eo ag-+ 1///(-Ch]mtjn ai_ ajeopnen ja ]joc nesen+ dicgp_dib 00 hagen 'EU7,EU03( EiPF omaincmdko.kmjoedi ai_ oce aclpdndodji ja nkecdadc kjnohdojodc aeaopmen(+ jccpmn eamgt Uceocem oce TLM meoadin ait kmjgdaemaodqe cakacdot _pmdib eh]mtjbeiendn di cphain dn
	ai_ 8 aehagen 'EU6,EU03( reme pne_ oj _ehjinomaoe oce _daaemeicen di nespag _daaemeiodaodji _pmdib eh]mtjbeiendn rdocdi oce kmenphkodqe TLM 'Djmid % Umat+ 1/04: Qccraiueg,Dpfp_a pifijri-?o AQ 1/+ iphemjpn TLM ceggn eskmenne_ oce kmjgdaemaodji hamfem Id56 ai_ cdbc
	ocao jccpmn ocmjpbc ocdn _eqegjkheioag rdi_jr-?gg haejm cjhkjieion ja oce pmjbeidoag ntnoeh % Naaaa+ 0878: Umat eo ag-+ 0878(-Rcpn+ re admno nop_de_ oce nelpeiodag hjmkcjbeieodc noekn geqegn ja oce noeh cegg hamfem QMV1 ';WUcrS .-m-n(-Gi cjiomano+ ocet reme iebaodqe ajm QMV0/+
	cjpg_ ]e qdnpagdne_ di 2B ';WUcrSa -3-.1(+ ai_ di_dqd_paggt nebheioe_-Djeopnen jg_em ocai gea_dib oj oce ajmhaodji ja oce cphai jgaacojmt.qjhemjianag ntnoehn+ oce akkeamaice ja oce a hamfem ja jgaacojmt einceaocdib ceggn 'a otke ja bgdag cegg rdoc htegdiaodib cakacdot( ai_ Fp,
	EU7+ ojj gambe ajm jpm JQDK hdcmjncjke+ reme _dnnecoe_ kmdjm oj kmjcenndib oj dhabe-admno EiPF,eskmenndib iepmjin ai_ oce didodaodji ja oce EiPF iepmjiag hdbmaojmt kmjcenn-AB+ a hamfem ja dhhaopme iepmjin 'Kampndcc % Uenoji+ 0881( ';WUcrS .-m-n(-Rcene
	j]nemqaodjin npbbeno ocao oce eh]mtjidc TLM cjioadin acodqegt kmjgdaemaodib kmjbeidojmn ocao
	0(.(1 9SdSlopmSnb Wn BOlSa Gi cphain+ oce jgaacojmt kgacj_en _eqegjk an ocdcfeidibn ja oce ecoj_emh ji oce qeiomjgaoemag cjpg_ ]e oce kmecpmnjmn ja oce iepmjin ai_ jgaacojmt einceaocdib ceggn hdbmaodib dioj oce
	Gi oce tjpibeno hage eh]mtj 'EU7(+ oce cap_ag odk ja oce KB ran di cgjne cjioaco rdoc oce nd_en ja oce cea_ amjpi_ oce adaoc reef ja benoaodji 'Kpggem % M'Pacdggt+ 1//3(-Ucdge oceme dn oegeicekcagji amjh oce ianag mebdji-
	UB ]po ca_ ijo teo apggt egjibaoe_ ';WUcrS -3 6-7( ai_ henjiekcmdc op]pgen noehhdib amjh beiemag abmeeheio a]jpo oce esdnoeice ja a TLM di oce cphai eh]mtj 'Qhdoc % Bcaoiabam+
	oce UB cjqeme_ oce oenodn kmdhjm_dph-Rce fd_ietn nodgg jccpkde_ a qeiomag kjndodji a_eaceio oj 1///(+ qemt gdooge diajmhaodji dn aqadga]ge a]jpo don _eqegjkheio ai_ hjgecpgam ndbiaopme-
	oce beidoag md_ben ';WUcrS -36(-?o EU8-4 'i < 0(-?o EU8-4+ oce KB apmocem egjibaoe_ agjib
	oce UB+ cjreqem+ ocet nodgg ca_ ijo apne_ ';WUcrSa -3 8-9(-Gi EU0/ hage ajeopnen 'i < 1(+ Feme+ re admno j]nemqe_ ocao oce kgacj_en diqabdiaoe ao AQ 05 'akkmjs-28 _at ja benoaodji( oj
	oce orj KB caqe apne_ ai_ esoei_e_ he_daggt ]eoreei oce orj UB pk oj oce pmjbeidoag ndipn-ajmh ndhkge jgaacojmt kdon ';WUcrS ., O-P(-?i diqabdiaodji ja oce he_dag jgaacojmt kgacj_e
	Gi ]joc canen+ cjreqem+ oce KB noamoe_ oj amabheio _jmnaggt ';WUcrS -3 :-; OnR ;WUcrS .16(-bdqen mdne oj oce kmenphkodqe qjhemjianag jmbai 'kTLM: ;WUcrS ., Q-R(-
	Rcdn mehiaio ja oce apne_ KB hdbco bdqe mdne oj oce kmjnoaodc pomdcge-?o jg_em aben+ npcc an Ue ocei aiagtne_ di a cphai eh]mtj ao AQ 05 oce eskmenndji ja oce omaincmdkodji aacojmn ?N,
	EU03 'i < 0(+ oce henjiekcmdc iekcmjin ja oce UB caqe mebmenne_ rcdge oce ekd_d_thdn _pcon 1α ai_ N?V5+ rcjne bma_e_ eskmenndji _eadie oce ndoe ja oce TLM aigabe di mj_eion 'Djmid eo
	ai_ qan _eaemein caqe ehembe_ ';WUcrS -3G(-?n kmeqdjpngt mekjmoe_ 'Hacj] eo ag-+ 1/01(+ ai ag-+ 1/00(-?N,1α dhhpijmeacodqdot cjpg_ ]e _eoecoe_ di oce ekd_emhdn+ _jmnag ai_ qeiomag
	akdcag KB mehiaio dn nodgg kmeneio ieso oj oce meoe oenodn ]t EU03 ';WUcrS -3 G-J(-cmaidjaacdag heneiccthe+ ai_ a aer ecoj_emhag ceggn rdocdi oce _jmnag ai_ qeiomag kjmodjin ja
	Qjs8 dn enneiodag oj oenoen _daaemeiodaodji di hagen ai_ eskmenndji ja don hPL? can admno ]eei oce menkdmaojmt ekdocegdph ';WUcrS ., O-P(-Gi oce ianag mebdji+ N?V5 eskmenndji ran cjiadie_
	_eoecoe_ amjpi_ AQ08,AQ10 'Faiget eo ag-+ 1///(-Sndib rcjge,hjpio dhhpijnoadidib ajm oj oce he_dag jgaacojmt ekdocegdph rdoc a _ecmeandib bma_deio ojram_n ?N,1α ,kjndodqe
	07/ 08/

( DnboUSnSaWa OnR molSQclOr aWUnObcrS oT GnGH nScrona Ob 8H 10

	1(,
	'O-P( ?N,1α ai_ N?V5 eskmenndji di a nabdooag necodji ja a AQ05 eh]mtj cea_-?N,1α
	dn eskmenne_ ]t _jmnag ai_ qeiomag cmaidjaacdag heneiccthe+ ai_ aer ecoj_emhag ceggn ja
	oce _jmnag ai_ qeiomag kjmodji ja oce menkdmaojmt ekdocegdph 'PC(-'P( Nas5 dn eskmenne_
	di ai jkkjndoe bma_deio oj ?N,1α+ _eadidib oce ianag iepmjekdocegdph ai_ oce kTLM
	'ammjr(-'Q( B?N noadidib ncjrdib ocao di oce jgaacojmt kgacj_e ai diqabdiaodji ja oce
	he_dag jgaacojmt kgacj_e 'KMN( ajmhn oce kTLM 'ammjr(-'R( EiPF* iepmjin
	_daaemeiodaoe jpond_e oce kTLM ai_ eskmenn BAV an njji an ocet noamo hdbmaodib acmjnn
	oce LK-'S(+ Camgt EiPF* ceggn 'ammjrn( ame _eoecoe_ ao oce ]jm_em ]eoreei oce LK
	ai_ oce ekdocegdph ja oce kTLM-'T( Jaoemag nabdooag necodji ja a AQ 05 cphai eh]mtj
	cea_ noadie_ rdoc B?NG-'U( Fdbc habidadcaodji ja oce ]jse_ amea di T-Rce iepmjiag
	hdbmaojmt hann 'KK+ ammjrn( eskmennen oce dhhaopme iepmjiag cegg hamfem BAV-
	EiPF iepmjin cjagenceice rdoc oce KK 'V-X(+ BLCP ai_ βGGG,op]* ceggn ame _eoecoe_
	di oce he_dag LK ajmhdib oce KK 'V+ ammjr( ai_ βGGG,op]* ceggn ame kmeneio _jmnaggt
	ojram_n oce _eqegjkdib jgaacojmt ]pg] 'V+ ammjrcea_(-βGGG,op]* iepmjin eskmenndib
	BLCP ehembe amjh oce MC 'W+ ammjrcea_n( ojram_n oce cjagenceice ja ceggn di oce LK
	di a ccamacoemdnodc ccadi,gdfe aancdji-'X(+ Fdbc habidadcaodji ja a βGGG,op]* cegg
	eskmenndib BLCP hjqdib amjh oce MC oj oce LK-
	V 4/ μh-?]]meqdaodjin9 DB9 Djme]madi: LK9 ianag heneiccthe: kTLM9 kmenphkodqe
	qjhemjianag jmbai: MC9 jgaacojmt ekdocegdph: KK9 hdbmaojmt hann: KMN9 he_dag
	jgaacojmt kgacj_e-

Qcage ]amn9 O 1// μh: P 0// μh: Q+ T 1// μh: R+ W 1/ μh: S+ X 0/ μh: dineo di X 4 μh: U-

DnboUSnSaWa oT GnGH nScrona OnR bVS "mWUrOborg mOaa"

	1(-
	Gi mj_eion+ eamgt EiPF iepmjin hdbmaoe ojbeocem rdoc a ceoemjbeiejpn cjagenceice ja kgacj_e,
	_emdqe_ ai_ iepmag,cmeno,_emdqe_ hdbmaojmt ceggn 'Djmid eo ag-+ 1/00( ai_ jgaacojmt asjin+
	cjggecodqegt cagge_ oce ©hdbmaojmt hann" 'Tagqem_e eo ag-+ 0881: Kdggem eo ag-+ 1/0/(-Rcdn cegg
	hdbmaodji kmece_en oce oambeodib ja jgaacojmt neinjmt asjin oj oce _eqegjkdib jgaacojmt ]pg]
	'MB(-Rce esdnoeice ja a ndhdgam hdbmaojmt hann di oce cphai eh]mtj can ijo teo ]eei
	_encmd]e_-Ue ocpn dhhpijga]egge_ cjinecpodqe nabdooag necodjin ja a AQ 05 eh]mtj ajm EiPF
	ai_ Bjp]gecjmodi 'BAV: ;WUcrS ., R& S& U(+ a hamfem ja dhhaopme hdbmaojmt iepmjin 'Egeenji
	eo ag-+ 0888(-Ue d_eiodade_ qemt aer '4/ di ojoag( dhhaopme EiPF,eskmenndib ceggn di oce ianag
	heneiccthe+ di oce he_dag kjmodji ja oce jgaacojmt kgacj_e ';WUcrS ., Q-S(+ a_eaceio oj oce
	]anag gahdia ja oce TLM+ ncjrdib ocao oce aclpdndodji ja cegg d_eiodot jccpmn jpond_e oce
	qjhemjianag ekdocegdph+ ai_ neqemag _atn eamgdem ocai kmeqdjpngt ocjpbco '_at 31 YQccraiueg,
	Dpfp_a eo ag-+ 0885Z(-
	?o ocdn noabe+ re agnj j]nemqe_ a hdse_ hann ja dhhaopme EiPF iepmjin eskmenndib edocem
	BAV ';WUcrS ., T-U( jm βGGG,op]pgdi ';WUcrS ., V-X(+ hdbmaodib acmjnn oce ianag heneiccthe
	ojram_n oce oegeicekcagji-Dpmocemhjme+ ocene kdjieem iepmjin agnj eskmenne_ Begoa.Ljocc,
	gdfe CED,megaoe_ mecekojm 'BLCP+ ;WUcrS ., V-X(+ a omainheh]maie kmjoedi nkecdadcaggt
	gjcagdne_ di oce _ei_mdoen ai_ cegg ]j_den ja kjnohdojodc iepmjin-
	Mpm kmeneio _aoa agnj npbbeno ocao oce hjmkcjbeieodc kmjbmahn _eadidib oce _eqegjkheio ja
	oce jgaacojmt ai_ qjhemjianag ntnoehn ai_ oce hjgecpgam ndbiaopme ja oce EiPF hdbmaojmt
	mjpoe ame ao geano kamogt cjinemqe_ acmjnn eqjgpodji 'Cdmafp eo ag-+ 1//1: Kdggem eo ag-+ 1/0/(-

9SdSlopmSnb oT bVS domSronOaOl OnR bSrmWnOl nSrdSa& OnR GnGH nScron mWUrObWon

	Whole mount immunostaining of GnRH	Development of the vomeronasal & terminal nerves
	]pi_gen+ rcdcc ehembe_ amjh oce TLM oj kmjeeco oj oce _eqegjkdib MB-Ma ijoe+ jigt aer _atn 1(.
	'akkmjsdhaoegt 4 _atn( aaoem ocedm didodag akkeamaice njhe EiPF iepmjin ca_ agmea_t eioeme_
	oce oegeicekcagji ai_ cjpg_ ]e neei di oce MB+ nekoph ai_ qeiomag nomdaoph ';WUcrS .-O(-
	Lepmjin ja oce TLL ai_ RL+ rcdcc ]egjib oj oce accennjmt jgaacojmt ntnoeh+ _eqegjk ?o AQ 07+ dhhpijga]eggdib ajm oce jgaacojmt einceaocdib cegg hamfem QMV0/ 'Bammap_ eo ag-+
	ndhpgoaiejpngt amjh oce he_dag kamo ja oce ianag _dnc+ ojbeocem rdoc EiPF iepmjin di 1/02: Djmid eo ag-+ 1/00: Kdggem eo ag-+ 1/0/( βGGG,op]pgdi ai_ EiPF meqeage_ ocao jgaacojmt
	hahhagn+ dicgp_dib cphain 'Kpggem % M'Pacdggt+ 1//3: Temiet eo ag-+ 1//1(-Rce TLL ai_ einceaocdib ceggn eirmakke_ TLL.RL asjin ';WUcrS .-V(-EiPF iepmjin dioemhdibge_ rdoc
	RL omaqeg ojbeocem acmjnn oce ianag mebdji 'Bmjri+ 0876(+ ehembdib amjh oce qjhemjianag QMV0/,kjndodqe ceggn ai_ dhhaopme hdbmaojmt iepmjin 'βGGG,op]pgdi,kjndodqe( di oce ianag
	ekdocegdph ai_ mpiidib he_daggt amjh oce jgaacojmt ekdocegdph ojram_n oce _jmnag mebdji ja oce heneiccthe+ ji ocedm rat amjh oce TLM oj oce _eqegjkdib ajme]madi ';WUcrS .-W-l(-
	MB-Rcedm ceiomag eiomt+ cjreqem+ _daaemn9 do can ]eei kmeqdjpngt ncjri ocao oce TLL meaccen
	oce _jmnag mebdji ja oce MB+ iahegt oce _eqegjkdib accennjmt jgaacojmt ]pg] '?MB(+ menkjind]ge ?n heiodjie_ a]jqe+ di hjno oemmenomdag qemoe]maoen+ qjhemjianag iepmjin kmjeeco oj oce ?MB-
	ajm cj_dib kcemjhjiag diajmhaodji aaoem ]dmoc+ rcemean oce RL kmjeecon ]joc qeiomaggt ai_ Rce kmeneice ja ai accennjmt jgaacojmt ntnoeh can agnj ]eei _jcpheioe_ _pmdib ajeoag gdae di
	_jmnaggt rdocdi oce ajme]madi+ kmdhamdgt oj oce nekoag+ ctkjocagahdc ai_ gdh]dc amean 'Neamnji+ cphain 'Bjnnt+ 087/: Acpac % Xceib+ 0876(-Fjreqem+ oceme dn ij eqd_eice nj aam ajm a
	0830a: Qcraiueg,Dpfp_a % Qdgqemhai+ 087/: Qccraiueg,Dpfp_a % Naaaa+ 0878: Temiet+ iepmjiag cjiiecodji ]eoreei oce TLM ai_ oce ?MB-Ue oenoe_ ocdn kjnnd]dgdot ]t kemajmhdib
	0876: Udmndb,Udecchaii % Mfa+ 1//1: Umat eo ag-+ 0878(-dhhpijcdnojccehdnomt ajm Lepmjkdgdi,1 'LPN,1( ai_ EiPF ji nabdooag necodjin ja EU 8
	cea_n+ rcdcc cjioadie_ ]joc oce TLM ai_ oce ?MB ';WUcrS .. O-R(-LPN,1+ oce mecekojm ajm
	Mpm dhhpijcdnojccehdcag nop_den ja AQ 07 eh]mtjn meqeage_ a hdse_ kjkpgaodji ja TLL ai_ Qehakcjmdi 2D+ dn cdbcgt eskmenne_ ]t a np]neo ja qjhemjianag neinjmt iepmjin di mj_eio
	RL asjin ehembdib amjh oce TLM+ omaqegdib acmjnn oce ianag nekoph+ cmjnndib oce cmd]mdajmh eh]mtjn ai_ agjib qjhemjianag asjin diiemqaodib oce ?MB 'Agjpodem eo ag-+ 1//1(-Ue agnj
	kgaoe ai_ kmjeecodib dioj oce oegeicekcagji ';WUcrS .-O(-Gi jocem hahhagn+ ocdn asjiag ncaaajg_+ j]nemqe_ nomjib LPN,1 eskmenndji di _eqegjkdib iepmjin ja oce TLM ao EU 8+ an regg an
	rcdcc nemqen an a np]nomaoe ajm oce hdbmaodji ja EiPF iepmjin+ eskmennen oce omaindeio asjiag rdocdi oce TLL an do cmjnne_ oce ianag heneiccthe ';WUcrS .. O-P( ai_ eioeme_ oce ]madi
	bgtcjkmjoedi 0 'R?E,0.Ajioacodi,1( 'Wjncd_a eo ag-+ 0884(+ oce iepmji,nkecdadc βGGG,op]pgdi ocmjpbc aeienomaodjin ja oce cmd]mdajmh kgaoe ';WUcrS ..Q(-EiPF iepmjin hdbmaoe_ di ocene
	'Edacj]did eo ag-+ 1//7( an regg an oce iepmjiag otke GGG dioemhe_daoe adgaheio kmjoedi kemdkcemdi mebdjin di odbco annjcdaodji rdoc LPN,1,kjndodqe ad]men ';WUcrS .. O-Q(-Kjmejqem+ aiagtndn ja
	'Umat eo ag-+ 0883(-Rcene hamfemn ame fijri oj ]e eskmenne_ ]t a np]neo ja _eqegjkdib oce TLM oambeo amea meqeage_ LPN,1,eskmenndib ad]men di oce ?MB ]po ijo oce hadi MB ';WUcrS
	jgaacojmt+ qjhemjianag ai_ oemhdiag asjin 'Ejmcah eo ag-+ 088/: 0880( ai_ oj cdbcgdbco oce ..R(-Rcene adi_dibn kmjqd_e nomjib eqd_eice ajm oce aiaojhdcag cjiiecodji ]eoreei oce cphai
	eiodme EiPF hdbmaojmt ncaaajg_ amjh oce jgaacojmt kdo oj oce he_dag nekoag amea 'Dpencfj % TLM ai_ ?MB-
	Umat+ 0883(-Feme+ re kmjqd_e eqd_eice ocao kemdkcemdi ';WUcrS .-R( ai_ R?E,0 ';WUcrS .-S(
	ame agnj eskmenne_ agjib ocdn ncaaajg_ ja qjhemjianag.oemhdiag asjin di AQ 08 cphai eh]mtjn-
	?o AQ 07,1/ 'akkmjs-33 oj 38 _atn ja benoaodji(+ re j]nemqe_ EiPF,dhhpijkjndodqe
	1/3	1/2

iepmjin jpond_e oce TLM ';WUcrS .-O(-Rcene ceggn reme hdbmaodib acmjnn oce ianag nekoph agjib βGGG,op]pgdi, ';WUcrS .-O( ai_ R?E,0,kjndodqe ';WUcrS .-T-U( TLL.RL asji

HWUV-rSaolcbWon -9 WmOUWnU oT bVS GnGH mWUrOborg pObVeOg Wn VcmOn SmPrgoa

	Whole mount immunostaining of GnRH
	Ue ieso kemajmhe_ rcjge,hjpio EiPF dhhpijga]eggdib ja a AQ 10 cphai eh]mtj 'akkmjs-;WUcrS .0
	42 _at ja benoaodji( ai_ _jcpheioe_ oce 2B _dnomd]podji ja EiPF iepmjin ';WUcrS .0 O-P(-
	?o ocdn noabe+ EiPF ceggn hdbmaoe_ rdocdi oce ]madi di ccadi,gdfe nompcopmen ai_ kmjcee_e_
	2B dhabdib ja njgqeio,cgeame_ jmbain '2BGQAM( dn a ndhkge njgqeio,]ane_ cgeamdib heocj_ _jmnaggt ai_ gaoemaggt ojram_n oce nekoph+ MB ai_ cjmoes ';WUcrS .0 O-P+ ammjrcea_n(-
	pne_ ajm omainkameiodndib oce ]madi 'Cmoümf eo ag-+ 1/01: Cmoümf % Bma_fe+ 1/02(-Rcdn heocj_ Kjmejqem+ njhe EiPF,kjndodqe ceggn ajmhe_ a gjjk ai_ noamoe_ opmidib qeiomaggt ojram_n oce
	can ]eei cjh]die_ rdoc dhhpijga]eggdib ajggjre_ ]t gdbco,nceeo ganem,ncaiidib hdcmjncjkt _eqegjkdib ctkjocagahpn ';WUcrS .0 O-P(-
	'JQK( oj nop_t iepmjiag cjiiecodqdot di hjpne eh]mtjn ai_ kjnoiaoag ]madin 'Cmoümf eo ag-+
	1/01: Cmoümf % Bma_fe+ 1/02: Begge eo ag-+ 1/03(-Feme+ re a_akoe_ ocdn oeccidlpe ajm oce admno ? aer _atn gaoem+ ao EU 8+ hait EiPF iepmjin reme nodgg ajpi_ di oce ianag cjhkamoheio di
	odhe oj a rcjge AQ 08 cphai eh]mtj 'akkmjs-37 _at ja benoaodji+ ;WUcrS ./(-Ucjge,hjpio cgjne annjcdaodji rdoc R?E,0,dhhpijmeacodqe TLL.RL asjin-Gi a__dodji+ njhe EiPF ceggn
	dhhpijga]eggdib ajm EiPF ai_ kemdkcemdi ajggjre_ ]t 2BGQAM jkodcag cgeamdib ai_ JQK ca_ annphe_ a kecpgdam mdib,gdfe _dnomd]podji+ ajmhdib orj nthheomdc cdmcgen amjpi_ oce
	kmjqd_e_ esceggeio cgeamdib ja oce odnnpe ai_ cdbc,menjgpodji dhabdib ja dhhpijagpjmenceio _eqegjkdib MB ';WUcrS .0 Q-R(-Gind_e oce ]madi+ EiPF iepmjin reme ij gjibem jmbaidue_ di
	ndbiagn ';WUcrS ./ O-P(-Rce kemdkcemdi aiod]j_t aggjre_ pn oj qdnpagdue hjojm ai_ neinjmt cjiodipjpn ccadin ]po reme maocem hjme rd_egt nkace_ ai_ ncaooeme_ acmjnn hpgodkge amean
	ad]men ja oce eiodme kemdkcemag iemqjpn ntnoeh di cphai eh]mtjn+ dicgp_dib cmaidag iemqen ai_ ';WUcrS .0 S-T(-
	iemqen diiemqaodib oce gdh]n ';WUcrS ./ O-P(+ di a__dodji oj oce ncaaajg_ ja jgaacojmt+
	qjhemjianag ai_ oemhdiag asjin j]nemqe_ a]jqe ]t cjiqeiodjiag 1B cdnojgjbt ';WUcrS .-R(-
	Fdbc,menjgpodji 2B dhabdib ja oce AQ 08 cea_ kemhdooe_ pn oj qdnpagdue hdbmaojmt EiPF
	iepmjin ai_ oce diomacmaidag kmjeecodjin ja oce oemhdiag iemqe ';WUcrS ./ Q-T(-Rce diomacmaidag
	kmjeecodjin ja oce RL ca_ agmea_t meacce_ oce he_dag nekoag amea ]t ocdn eh]mtjidc noabe-
	Sieskecoe_gt+ a cjind_ema]ge np]neo ja RL ad]men nkmjpoe_ _jmnaggt ai_ gaoemaggt oj oegeicekcagdc
	mebdjin cjmmenkji_dib oj oce iejcjmoes ai_ oce _eqegjkdib cdkkjcahkpn ';WUcrS ./ R-T(-Ue
	ajpi_ ocao EiPF iepmjin reme cjindnoeiogt epsoakjne_ oj oce kemdkcemdi,kjndodqe TLL.RL
	rcdge hdbmaodib amjh oce ijne dioj ocene oegeicekcagdc amean ';WUcrS ./ R-T(-
	Ue ieso jkodcaggt ngdce_ oce dhhpijga]egge_ cea_ ja oce AQ 08 eh]mtj ';WUcrS ./U( ai_
	aiagtne_ ocene _dbdoag cjmjiag ngdcen-Rce aaco ocao EiPF iepmjin akkeam ajm oce admno odhe di
	oce dhhe_daoe qdcdidot ja oce TLM ai_ ijrceme egne apmocem enoa]gdncen oce TLM an ocedm ndoe
	ja jmdbdi ';WUcrS ./U(-Rcene nop_den agnj cjiadmh ocao oce TLM hadioadin cjiodipdot rdoc oce
	jgaacojmt ekdocegdph di hjme cap_ag kjndodjin ';WUcrS ./U(-
	1/4 1/8

( LVolS-mocnb WmmcnolOPSllWnU OnR -9IH8D QlSOrWnU oT O 8H ,1 SmPrgo OnR beo GL 3 ToSbcaSa(

	'O-P( Jaoemag ai_ j]gdlpe kmjeecodjin ja oce rcjge cea_ ja a AQ 08 eh]mtj
	dhhpijnoadie_ ajm EiPF-Acadin ja EiPF iepmjin eioem oce ]madi ai_ kmjbmenn edocem
	_jmnaggt 'ammjrn( jm qeiomaggt 'ammjrcea_n( ojram_ oce _eqegjkdib ctkjocagahpn-'Q-R(+
	rcjge,hjpio EiPF.R?E,0 dhhpijga]eggdib ja a EU 8 ajeoag ijne-'S-T(+ _jmnag ai_
	gaoemag kmjeecodjin ja a EU 8 cea_ dhhpijnoadie_ ajm EiPF-?o ocdn noabe+ EiPF
	iepmjin ame _dnomd]poe_ di neqemag ]madi amean+ dicgp_dib oce ctkjocagahpn-
	Qcage ]amn9 O-P 4// μh: Q-R 1// μh: S 2// μh: T 3// μh-?]]meqdaodjin9 AV9 cjmoes:
	FWN9 ctkjocagahpn: MB9 jgaacojmt ]pg]: QCN9 nekoph-
	1(/

9WabrWPcbWon OnR ncmPSr oT GnGH nScrona Wn bVS VcmOn ToSbOl PrOWn Gi

  mj_eion+ EiPF iepmjin hdbmaoe dioj oce ajme]madi ai_ akkeam oj _eoacc amjh oce kemdkcemdi, kjndodqe oemhdiagn ja TLL.RL ad]men ]eajme eioemdib oce nekoag,kmejkodc amea 'Wjncd_a eo ag-+ 0884(-Gi jm_em oj _eoemhdie rceocem ocdn ran agnj oce cane di cphain+ cjmjiag necodjin ja a AQ Ue _d_ ijo j]nemqe ait nes _daaemeice di oce iph]em ja EiPF ceggn di EU 6,0/ ajeopnen 'i < 3 hagen+ heai EiPF cegg iph]em < 00012 ± 1704: i < 3 aehagen+ heai EiPF cegg iph]em < 0/454 ± 0582: o,oeno N < /-76/5(-?o eacc noabe+ re agnj lpaiodade_ oce megaodqe

	Distribution & number of GnRH neurons
	ceme re kmjqd_e eqd_eice ajm ai pieskecoe_ _jmnag hdbmaojmt kaocrat ajm EiPF iepmjin+ _dmecoe_ ojram_n kaggdag ai_ np]kaggdag oegeicekcagdc mebdjin ';WUcrS .1P+ me_ ammjr(-Rj pi_emnoai_ di bmeaoem _eoadg oce aiaojhdcag _dnomd]podji ja EiPF iepmjin di cphai ajeoag ';WUcrS .3O(-_dnomd]podji ja EiPF cegg ]j_den di 2 _daaemeio amean9 oce ijne.MB+ ai_ oce qeiomag ai_ _jmnag ;WUcrS .1
	]madin+ re kemajmhe_ 2B mecjinompcodji aiagtndn ja nemdag necodjin ao ocdn ajeoag noabe 'EU 8+ i hdbmaojmt nomeahn ';WUcrS .3P(-?o AQ 05+ EiPF,dhhpijmeacodqdot ran menomdcoe_ oj oce ijne-
	< 1: ;WUcrS .1Q(-Mpm aiagtndn cjiadmhe_ ocao EiPF iepmjin hdbmaoe_ dioj oce ]madi agjib ?o AQ 06,07+ akkmjsdhaoegt 5/% ja oce ceggn reme hdbmaodib rdocdi oce ijne+ 25% ca_ eioeme_
	orj hadi hdbmaojmt kaocratn+ dicgp_dib oce iergt d_eiodade_ _jmnag kaocrat-Rce gaooem oce ]madi agjib oce _jmnag hdbmaojmt nomeah ai_ 3% ca_ noamoe_ oj opmi qeiomaggt ojram_n oce
	kaocrat cjhkmdne_ orj cjhkjieion9 ]anag ajme]madi-Bpmdib np]nelpeio noaben 'AQ 08 oj EU 01+ i < 00: ;WUcrS .3Q(+ oce iph]em
	ja ceggn di oce ijne kmjbmenndqegt _ecmeane_+ rdoc a cjicjhdoaio dicmeane di ceggn di oce _jmnag
	, a he_dag jie meaccdib oce nekoph._dabjiag ]ai_ ja Bmjca+ di_pndph ai_ qeiomag hdbmaojmt kaocratn-?o oce gaoeno odhe kjdio aiagtne_ 'EU 00,01+ i < 2(+ jigt
	bmdneph.kmenphkodqe cdkkjcahkpn ai_ mjnomj,he_dag iejcjmoes 12% ja EiPF iepmjin reme gjcaoe_ di oce hjme mjnomag mebdjin 'ijne.MB(-
	, a gaoemag jie meaccdib oce qeiomag nomdaoph+ kdmdajmh cjmoes ai_ ahtb_aga ';WUcrS .1Q(-
	?i aiaojhdcag aogan ja oce _eqegjkdib cphai EiPF ceggn dn cpmmeiogt piaqadga]ge-Rj beiemaoe
	12 ajeopn 'akkmjs-EU 7( reme dhhpijga]egge_ ajm kemdkcemdi ai_ EiPF-Nemdkcemdi,kjndodqe a _eoadge_ _dnomd]podji hak ja EiPF iepmjin di EU 01 ajeopnen 'oce gaoeno _eqegjkheioag noabe
	ad]men kmjeecoe_ _eekem ocai eskecoe_+ oj oce he_dj]anag ctkjocagahpn ai_ _eqegjkdib he_dai aqadga]ge ajm ocene nop_den(+ re dhhpijga]egge_ nemdag cjmjiag necodjin ja EU 01 cea_n ai_
	ehdieice ';WUcrS .1O(-EiPF iepmjin reme _eoecoa]ge di ocene mebdjin+ ]po agratn di odbco kemajmhe_ a 2B mecjinompcodji ja EiPF,dhhpijmeacodqe cegg ]j_den ai_ ad]men 'i < 1: ;WUcrS
	akkjndodji oj kemdkcemdi,kjndodqe ad]men mdbco pk oj ocedm oambeo ndoen ';WUcrS .1O+ dineo(+ .2 O-P(-Rcdn eskemdheio meqeage_ a npmkmdndibgt rd_e.]mja_ _dnomd]podji ja EiPF cegg ]j_den
	di_dcaodib ocao hdbmaodib EiPF iepmjin di cphain ieqem gjne cjioaco rdoc oce RL asjiag ai_ ad]men di ctkjocagahdc ';WUcrS .2 O-R( an regg an neqemag esomactkjocagahdc amean+ dicgp_dib
	ncaaajg_ mdbco pk oj ocedm oambeo ndoen-Rcdn npbbenon a api_aheioag _daaemeice ]eoreei mj_eion oce jgaacojmt ]pg]n+ ceme]mag cjmoes+ cdkkjcahkpn+ kdmdajmh cjmoes+ ahtb_aga ai_ ca]eipga
	ai_ cphain di oce hj_e ja hdbmaodji ja EiPF iepmjin _pmdib oce gano kcane ja ocedm ejpmiet-';WUcrS .2 O& P& S(-
	?goemiaodqegt+ TLL.RL asjiag oemhdiagn hdbco agnj kemndno di ocene amean ja mj_eion ]po ocet Ue ieso cjpioe_ EiPF ceggn ao _daaemeio _eqegjkheioag noaben ]eoreei EU 4-4 'AQ 05( ai_
	ij gjibem eskmenn kemdkcemdi-EU 01-?o AQ 05 'oce eamgdeno eh]mtjidc noabe re ca_ accenn oj+ i < 0(+ re j]nemqe_ 4/ EiPF
	?o EU 8+ di feekdib rdoc oce d_eiodadcaodji ja a _jmnag.gaoemag ]maicc ja oce RL di AQ 08 iepmjin+ agg ja rcdcc reme menomdcoe_ oj oce ianag mebdji+ cjiadmhdib ocao oce ]dmoc_aoe ja EiPF
	eh]mtjn+ EiPF iepmjin reme _dnomd]poe_ agjib orj _daaemeio hdbmaojmt nomeahn-Rce admno+ a iepmjin di cphain dn amjpi_ benoaodji _at 28 ';WUcrS .3O(-Migt a aer _atn gaoem 'EU 59 AQ
	qeiomag hdbmaojmt kaocrat _dmecoe_ ojram_n oce kmenphkodqe ctkjocagahdc mebdjin ';WUcrS .1P+ 06,07+ i < 2(+ oce iph]em ja EiPF iepmjin ca_ ephke_ oj 6840 ± 1///+ npbbenodib ocao hjno
	rcdoe ammjr(+ can kmeqdjpngt ]eei _jcpheioe_ di cphain 'Qccraiueg,Dpfp_a % Naaaa+ 0878: ja ocene ceggn ame agmea_t ]jmi ]t oce 28oc _at ja benoaodji+ ai_ ocao EiPF iepmjiag
	Qccraiueg,Dpfp_a eo ag-+ 0885( ai_ di jocem qemoe]maoen 'Djmid % Umat+ 1/04(-Gi a__dodji+ _daaemeiodaodji jccpmn ]eoreei oce 28oc ai_ 33oc _at ';WUcrS .3O(-Mi aqemabe+ amjpi_ 0////
	EiPF iepmjin reme _eoecoa]ge ao 3 _eqegjkheioag noaben9 AQ 06 ai_ 07 ai_ EU 00 ai_ 01
	10/

( GnGH nScrona mWUrObS TolloeWnU O RoraOl OnR O dSnbrOl mWUrOborg pObVeOg PobV Wn VcmOn OnR mocaS ToSbcaSa

	'O( Pekmeneioaodqe cjmjiag necodji ja a EU 8 ajeoag ctkjocagahpn dhhpijga]egge_ ajm
	EiPF 'bmeei( ai_ kemdkcemdi 'me_(-Nemdkcemdi,dhhpijkjndodqe ad]men kmjeeco oj oce
	]anag ctkjocagahpn ai_ _eqegjkdib he_dai ehdieice-Gineo di 'O( ncjrn ocao EiPF
	iepmjin hdbmaoe oj ocedm adiag ctkjocagahdc oambeo amean di odbco annjcdaodji rdoc oce
	kemdkcemdi,kjndodqe ad]men-'P( Pekmeneioaodqe nabdooag necodji ja a AQ 12 ajeoag ]madi
	dhhpijga]egge_ ajm EiPF-EiPF iepmjin eioem oce ]madi ajggjrdib a _jmnag 'me_
	ammjr( ai_ a qeiomag 'rcdoe ammjr( hdbmaojmt kaocrat-Gineo di P ncjrn a cdbc
	habidadcaodji ja hdbmaojmt EiPF ceggn di oce _jmnag kaocrat-'Q( Dmjio 'geao( ai_
	kemnkecodqe 'mdbco( qdern ja a 2B hj_eg ja oce EiPF iepmjin cegg ]j_den _dnomd]podji di
	a 8 EU eh]mtj-Cacc cegg dn mekmeneioe_ ]t a nkceme '0// μh di _daheoem( cjgjpme_
	accjm_dib oj ocedm gjcaodji 'gebei_ ji oce geao(-Rmainkameio cjiojpmn ja ianag
	heneiccthe 'LQ(+ jgaacojmt ]pg] 'MB( nekoph._dabjiag ]ai_ ja Bmjca 'QCN.BB( ai_
	di_pneph bmdneph.cdkkjcahkpn ame agnj ncjri ajm meaemeice-Gi oce dineo+ oce kjndodji
	ja ocene cjiojpmn+ ojbeocem rdoc oce ianag opm]diaoen 'ctai( dn ncjri-'R-S( Jaoemag+ 'T(
	amjioag+ 'U( cap_ag ai_ _jmnag kmjeecodjin 'V-W( ja oce rcjge cea_ ja ai C05-4 hjpne
	eh]mtj dhhpijnoadie_ ajm EiPF ai_ cgeame_ pndib 2BGQAM-?mmjrcea_n di_dcaoe
	ccadin ja EiPF iepmjin eioemdib oce ]madi ai_ kmjbmenndib _jmnaggt-EiPF iepmjin
	ame ajpi_ di oce iejcjmoes 'LAV(+ nekoag._dabjiag ]ai_ ja Bmjca 'QCN.BB( ai_
	ctkjocagahpn 'FWN: ammjrn di S(+ amjpi_ oce jgaacojmt ]pg]n 'MB: ammjr di T(-LAV
	ai_ kdmdajmh cjmoes 'NAV: ammjrn di U ai_ V( ai_ di _eek ]madi amean cjmmenkji_dib oj
	ajmids ai_ _eqegjkdib cdkkjcahkpn 'ammjr di W(-LK9 ianag heneiccthe-Qcage ]amn9
	a+ 0// μh: dineo di O 1/ μh: P 4/ μh: dineo di P 0/μh: R 3// μh: S 1// μh: T 07/ μh:
	U-W 5// μh-

;WUcrS .2( 9WabrWPcbWon oT GnGH QSll PoRWSa OnR nScrWbSa Ob GL 1,(

  'a( Dmjio 'geao( ai_ kemnkecodqe 'mdbco( qdern ja a 2B hj_eg ja oce EiPF iepmjin cegg ]j_den _dnomd]podji di a EU 01 eh]mtj-Cacc cegg dn mekmeneioe_ ]t a nkceme '0// μh di _daheoem( cjgjpme_ accjm_dib oj ocedm gjcaodji 'nee gebei_ ji oce geao(-Rmainkameio

	eo ag-+ 0883(+ ocao ceoemj_dhemdnen rdoc jie ja neqemag otke G RED,β mecekojmn '?cqP0 Y?JI1Z+ Ddiaggt+ pndib ai pi]dane_ rcjge beijhe nelpeicdib 'UEQ( akkmjacc+ re d_eiodade_ ndbidadcaio
	BKNP0a Y?JI2Z ai_ BKNP0] Y?JI5Z(+ ai_ mecmpdon QK?B kmjoedin ocao np]nelpeiogt eqd_eice ajm annjcdaodji ]eoreei apicodjiag hpoaodjin di oce ?KF beie ai_ AFF-Ajggecodqegt+
	pi_embj ipcgeam omaingjcaodji oj mebpgaoe oambeo beie eskmenndji 'Hjnnj eo ag-+ 1//2(-?KF dn jpm _aoa meqeag a ijqeg apicodjiag mjge ja ?KF di oce _eqegjkheio ja EiPF iepmjin+ einpmdib
	oce jigt fijri gdbai_ ja ?KFP1+ npbbenodib ocao odnnpen eskmenndib ocdn mecekojm ame gdfegt oj ocedm akkmjkmdaoe eiomaice dioj oce ]madi ai_ ocet kmjqd_e beieodc eqd_eice ocao ?KF ndbiaggdib
	]e oambeon ja ?KF-Fjreqem+ oce njge njpmce ja ?KF _pmdib eh]mtjidc _eqegjkheio dn dinpaadcdeict cai cjiomd]poe oj a AFF kceijotke di cphain
	cjind_eme_ oj ]e oce oenodn+ rcdcc kmj_pcen ai_ necmeoen ?KF+ menkjind]ge ajm didodaodib
	mebmenndji ja oce Kpggemdai _pcon+ ai_ ocpn cjiomjggdib ijmhag hage nespag _daaemeiodaodji 2(,
	'Becmdibem eo ag-+ 0883(-
	Bjoc di hdce ai_ cphain+ cjhjutbjpn hpoaodjin ja oce ?KF 'MKGK9 5//846( jm ?KF
	mecekojm 'MKGK9 5//845( beien gea_ oj kemndnoeio Kpggemdai _pco nti_mjhe 'NKBQ(+
	cgeamdib ai_ rcjge,hjpio dhhpijcdnojccehdcag oeccidlpen 'Begge eo ag-+ 1/03+ 1/06: Aanjid
	eo ag-+ 1/05: Cmoümf eo ag-+ 1/01( oj heodcpgjpngt nop_t oce 2B jmbaiduaodji ja oce EiPF ai_
	jgaacojmt ntnoehn di ?KFP1 rdg_,otke ai_ fijcf,jpo eh]mtjn-Rcene eskemdheion cjiadmhe_
	ocao ?KF,_eaecodqe ndbiaggdib gea_n oj a]ijmhag _eqegjkheio ja oce jgaacojmt ai_ oemhdiag
	cjiojpmn ja ianag nekoph 'LQ(+ jgaacojmt ]pg] 'MB(+ gaoemag jgaacojmt omaco 'JMR( ai_ iemqen ai_ _eaecodqe eh]mtjidc hdbmaodji ja oce EiPF ceggn oj oce ]anag ajme]madi+ gea_dib oj
	jkodc omaco 'MR( ame agnj ncjri ajm meaemeice-Fdbcem habidadcaodji ja a nhagg _eoadg ja a me_pce_ ndue ja ocdn iepmjiag kjkpgaodji di a_pgo ]madin ai_ _dhdidnce_ jqpgaodji-Sndib
	oce 2B hj_eg dn ncjri-'P( Qahe qdern ja oce 2B hj_egn di O( ncjrdib oce _dnomd]podji
	ja EiPF ad]men 'me_ ]amn(-'Q-S( Pekmeneioaodqe necodjin ja a EU 01 ajeoag ]madi _daaemeio eskemdheioag akkmjaccen+ re _ehjinomaoe_ ocao ?KF kmjhjoen oce hdbmaojmt acodqdot
	ja dhhjmoagdue_ EiPF ceggn ocmjpbc ?KFP1.BKNP0] ndbiaggdib ai_ acodqaodji ja oce K?NI
	kaocrat-

dhhpijga]egge_ ajm EiPF-EiPF oemhdiagn ame agmea_t _eoecoa]ge di oce he_dai ehdieice 'KC+ ammjrn di Q( ai_ EiPF eskmenndib ceggn ame ajpi_ di oce ctkjocagahpn 'FWN+ R( ai_ kdmdajmh cjmoes 'NAV+ S(-Qcage ]amn9 Q 3/ μh: R-S 0/ μh-ccamacoemdne_ ]t oce meoeiodji ja Kpggemdai _pco _emdqaodqen9 oce poempn+ Daggjkdai op]en+ ai_ pkkem kamo ja oce qabdia+ di jocemrdne ijmhaggt qdmdgdne_ beieodc hagen '35VW( 'Becmdibem eo ag-+ 0883: Beggqdgge eo ag-+ 1//3: Hjnnj % _d Ageheioe+ 1//2: Kdncdia eo ag-+ 0888: Mmqdn eo ag-+ 1//7(-Feme+ re mekjmo eh]mtjidc eskmenndji ja ?KF di esoma,bjia_ag odnnpen+ iahegt di jgaacojmt ai_ qjhemjianag mecekojm iepmjin an regg an ji ocedm asjin+ agjib rcdcc EiPF iepmjin hdbmaoe-Ue ncjr ocao hdbmaojmt EiPF ceggn ai_ oce jgaacojmt.qjhemjianag ncaaajg_ eskmenn ]joc ?KF ai_ ?KF mecekojmn+ rcdge kcamhacjgjbdcag kemopm]aodji ja oce ?KF.?KFP1 ndbiag omain_pcodji kaocrat di qdqj agoemn EiPF hdbmaodji-Dpmocemhjme+ re ehkgjte_ odnnpe,

6BH OnR Wba aWUnOllWnU pObVeOg OrS SfprSaaSR Wn OnR OrocnR bVS GnGH mWUrOborg pObVeOg

Ue caqe meceiogt ncjri ocao EiPF iepmjin ]joc di hjpne ai_ cphai ajeopnen eskmenn ?KFP1 _pmdib ocedm hdbmaodji 'Adhdij eo ag-+ 1/05(-Ue ocpn njpbco oj pi_emnoai_ rceocem oceme ran a gjcag njpmce ja ?KF di oce ianag cjhkamoheio ocao hat mebpgaoe EiPF hdbmaodji-Opagdoaodqe NAP ajm ?KF+ ?KFP1+ don cj,mecekojmn ai_ caijidcag diomaceggpgam ndbiaggdib kaocratn meqeage_ hPL?n eskmenndji ja agg beien 'akamo amjh QK?B7( di oce eh]mtjidc ijne ao C00-4 ';WUcrS /1O(-Ue ocei kemajmhe_ lpagdoaodqe ai_ lpaiodoaodqe NAP aiagtnen ja D?AQ, dnjgaoe_ EDN,eskmenndib EiPF iepmjin amjh EiPF99EDN hdce 'Qkembeg eo ag-+ 0888( ai_ meqeage_ eskmenndji ja ?KF omaincmdko di EiPF iepmjin amjh eamgt eh]mtjidc _eqegjkheio 'C01-4( oj a_pgocjj_ 'NL8/: ;WUcrS 1P-R(-

6BH OnR Wba aWUnOllWnU pObVeOg Wa SfprSaaSR Wn bVS SmPrgonWQ noaS

  e gjcagdne_ oj oce qjhemjianag jmbai 'TLM(+ jgaacojmt ekdocegdph 'MC( ai_ oj kmenphkodqe TLL.RL ad]men 'an regg an hdbmaodib EiPF iepmjin ocehnegqen(+ di_dcaodib ocao do dn eskmenne_ agg agjib oce EiPF hdbmaojmt mjpoe ocmjpbc oce ijne-

	Invalidation of AMHR2 alters GnRH development
	2(-
	;WUcrS /1( 'O( Qccehaodc ja a hjpne eh]mtj di_dcaodib oce kgaie ja _dnnecodji oj mehjqe oce ianag
	cjhkamoheio-Pekmeneioaodqe lpagdoaodqe NAP ]ai_n ame ncjri ajm oce eskmenndji ja
	?KF+ don j]gdbaojmt mecekojm ?KFP1+ don fijri cj,mecekojmn ?cqP0+ BKNP0a+
	BKNP0] ai_ don cganndcag diomaceggpgam ndbiaggdib kaocratn+ QK?B0.4.7 ai_ β,
	caoeidi-?gg cjhkjieion ja oce ?KF ndbiaggdib kaocrat ame kmeneio di a_pgo ]madi gtnaoe
	ai_ eskmenndji ja agg cjhkjieion esceko QK?B7 reme ajpi_ di oce eh]mtjidc ijne ao
	C00-4 'P( nccehaodc dggpnomaodib oce D?AQ ja EiPF99EDN hdce oj dnjgaoe a EiPF cegg
	kjkpgaodji-'Q( Opagdoaodqe NAP _ehjinomaodib ?KF dn eskmenne_ ]t hdbmaodib EiPF
	Cs qdqj cpgopmen ja C00-4 ianag eskgaion caqe ]eei pne_ oj nop_t aacojmn mebpgaodib EiPF ?]]meqdaodjin9 ?KF9 aiod,Küggemdai cjmhjie: ?KFP19 ?KF mecekojm1: ?cqP09
	?codqdi mecekojm0. ?codqdi gdfe fdiane 1 '?JI1(: BKNP0a9 Bjie hjmkcjbeidc kmjoedi hdbmaodji ]t ]joc jpm bmjpk 'Edacj]did eo ag-+ 1//3+ 1//6( ai_ jocemn 'Dpencfj % Umat+ 0883(-mecekojm0a.?JI2: BKNP0B9 Bjie hjmkcjbeidc kmjoedi mecekojm0].?JI5: Bdq9 _atn
	?o 3 _atn di qdomj 'BGT(+ jgaacojmt asjin+ rcdcc eskmenn β,op]pgdi 'RSH0(+ ehembe amjh oce di qdomj: LKA9 ianag heneiccthe: MC9 jgaacojmt ekdocegdph: R?E,09 omaindeio asjiag
	ianag eskgaio odnnpe hann ai_ EiPF iepmjin ]ebdi hdbmaodib jpo amjh oce eskgaio+ odbcogt bgtcjkmjoedi.cjioacodi1: RSH09 βGGG,op]pgdi: TLM9 qjhemjianag jmbai-
	annjcdaoe_ oj ocjne ad]men ';WUcrS /1S(-Ue beiemaoe_ ianag eskgaion amjh EiPF99EDN eh]mtjn
	ai_ ncjr ocao aiodnema abadino ?KF ga]egn hdbmaodib EiPF iepmjin ao 3 _atn di qdomj ';WUcrS
	/1 S-T(+ cjiadmhdib ?KF kmjoedi eskmenndji di ocene ceggn-
	12/

Ue agnj qemdade_ ocao oce ?KF kmjoedi dn eskmenne_ di qdqj ]t dhhpijga]eggdib ja cjmjiag necodjin ja oce ianag cjhkamoheio ao

C02-4

';WUcrS /1 U-Y(-?o ocdn odhe+ ?KF eskmenndji dn ajpi_ oj ]ceggn ao C01-4+ ai_ ?KF eskmenndji dn agnj ajpi_ di oce cea_ ao ocdn odhe kjdio-'R( lNAP ncjrdib oce megaodqe a]pi_aice ja ?KF hPL? eskmenndji di EiPF ceggn _pmdib eh]mtjbeiendn ai_ kjnoiaoag gdae-'S( Apgopme ja a ianag eskgaio aaoem 3 _atn di qdomj+ ao ocdn kjdio jgaacojmt asjin ga]egge_ rdoc RSH0 'me_( cai ]e neei hdbmaodib jpo ja oce eskgaio+ rdoc EiPF ceggn 'bmeei( cgjnegt akkjne_-'T( InaSb oT S+ ocene hdbmaodib EiPF ceggn eskmenn ?KF es qdqj-'U( Ajmjiag necodji ja a hjpne ijne ao C02-4 rdoc ]joc oce MC ai_ TLM kjndodqe ajm ?KF dhhpijmeacodqdot 'me_(-'V-Y( InaSb oT U+ ?KF dn eskmenne_ ]t R?E,0 kjndodqe ad]men 'rcdoe(+ ocene ad]men hdbmaoe amjh oce TLM oj oce jgaacojmt ]pg]+ kmjqd_dib a hdbmaojmt ncaaajg_ ocao EiPF iepmjin ajggjr oj meacc oce ]madi-'U-Y( Fjeccno ']gpe( pne_ an a ipcgeam cjpioemnoadi-

EVOrmOQoloUWQOl OnR USnSbWQ WndOlWRObWon oT 6BHG, RWarcpba GnGH nScronOl mWUrObWon OnR bVS olTOQborg)bSrmWnOl nSrdS bOrUSbWnU

  Gi gdbco ja ocene menpgon+ re njpbco oj _eoemhdie rceocem beieodc diqagd_aodji ja ?KFP1 rjpg_ gea_ oj ndhdgam _eaecon di oce EiPF hdbmaojmt kmjcenn ai_ _eqegjkheio ja oce ML ai_ RL-Ue kemajmhe_ a _eoadge_ aiagtndn ja rdg_ otke ai_ ?KFP1 ,.Rce aiaojhdcag gjcaodjin ja oce eiodme EiPF kjkpgaodji cjpg_ ]e annenne_ di ]joc bmjpkn ai_ mekmeneioaodqe dhaben ame kmeneioe_ di ;WUcrS /-O-T-Gi ?KFP1 ,., eh]mtjn+ EiPF iepmjin akkeame_ hjme gdfegt oj cgpnoem di oce ianag cjhkamoheio+ rdoc aerem dhhpijmeacodqe iepmjin Sndib ocdn oeccidlpe+ do ran kjnnd]ge oj ]eooem qdnpagdne oce eiodme diiemqaodji ja oce MB di rdg_,otke qemnpn hpoaio eh]mtjn an regg an oce kmjbmenndji ja oce RL kmjeecodjin ai_ _dnomd]podji ja EiPF iepmjin rdocdi oce qDB-

	?o C03-4+ oce ojoag iph]em ja EiPF iepmjin ran cjhkama]ge ]eoreei cjiomjg ai_ ?KFP1,
	L? omeaoe_ eh]mtjn 'i < 3 ajm agg bmjpkn: ;WUcrS /,U(+ di_dcaodib ocao ?KFP1 iepomagdnaodji
	ca_ ij eaaeco ji EiPF iepmji npmqdqag-Fjreqem+ a ndbidadcaio accphpgaodji ja EiPF ceggn di
	oce ianag cjhkamoheio+ cjicjhdoaio oj _ecmeane_ cegg iph]emn rdocdi oce ]madi+ di_dcaoe_ j]nemqe_ di oce qDB ';WUcrS /-Q-R: ammjrn(+ cjindnoeio rdoc oce menpgon amjh oce
	?n ?KFP1 dn oce jigt mecekojm fijri oj ]di_ ?KF+ don eskmenndji dn a iecennamt melpdmeheio a]ijmhag cegg hdbmaodji di oce ?KFP1,L? dieecoe_ eh]mtjn ';WUcrS /,V(-Gi a__dodji+ rcdge kcamhacjgjbdcag ]gjcfabe ja ?KFP1 mekjmoe_ a]jqe-? 2,Bdheindjiag nebheioaodji ai_
	ajm odnnpen oj ]e menkjindqe oj oce acodjin ja ?KF-Ue ocemeajme diqenodbaoe_ rceocem acpoe EiPF ceggn ijmhaggt opmi qeiomaggt ojram_n oce ]anag ajme]madi+ di ?KFP1,L? eh]mtjn+ mei_emdib ran agnj pi_emoafei oj ]eooem dnjgaoe Nemdkcemdi ad]men ai_ EiPF iepmjin ';WUcrS /-
	kcamhacjgjbdcag ]gjcfabe ja oce mecekojm rdoc ai ?KFP1 iepomagdndib aiod]j_t '?KFP1, L?( cjpg_ aaaeco EiPF hdbmaodji ai_.jm oce jgaacojmt ntnoeh-Rcdn ran accdeqe_ ]t di poemj dieecodji ja ?KFP1,L? oambeoe_ oj oce jgaacojmt kdo di C01-4 eh]mtjn ai_ np]nelpeio aiagtndn ja EiPF hdbmaodji ai_ don asjiag ncaaajg_ 37 cjpmn gaoem 'eskemdheio nccehaodc ;WUcrS /,O(-Ajmmeco oambeodib ja oce dieecodji ndoe ran ancemoadie_ ]t oce pne ja oce Dgpjmjbjg_ omacem-? mekmeneioaodqe dhabe ja Dgpjmjbjg_ pkoafe ai_ EiPF,dhhpijmeacodqdot dn ncjri di ;WUcrS /,P-Ghhpijga]eggdib rdoc Nemdkcemdi+ a iepmji,nkecdadc dioemhe_daoe adgaheio kmjoedi eskmenne_ ]t mj_eio neinjmt ai_ apojijhdc asjin 'Namtnef % Ejg_hai+ 0877(+ dicgp_dib oce _eqegjkdib jgaacojmt iemqe 'ML(+ TLL ai_ RL 'Aanjid eo ag-+ 1/05: Dpencfj % Umat+ 0883(+ ran pne_ oj annenn oce _eqegjkheio ja oce TLL.RL ao C03-4 ';WUcrS /,Q-T(-TLL.RL _eqegjkheio kmjbmenne_ an can kmeqdjpngt ]eei mekjmoe_ 'Wjncd_a eo ag-+ 0884( di nagdie dieecoe_ bmjpkn: cjreqem+ a]ijmhag ML.RL oambeodib jccpmme_ di eh]mtjn dieecoe_ rdoc ?KFP1,L?-Gi ?KFP1,L? omeaoe_ eh]mtjn+ oce asjiag diiemqaodji ja oce jgaacojmt ]pg] 'MB( akkeame_ dicjhkgeoe an cjhkame_ oj cjiomjgn ';WUcrS /,Q& R(-Rcdn _daaemeice di asjiag oambeodib ran hait EiPF ceggn reme ajpi_ oj hdbmaoe _jmnaggt ojram_n oce cjmoes ';WUcrS /,R( ai_ aerem iepmjin meacce_ oce qDB mebdji ';WUcrS /,T(-V-W(-ceggn di ?KFP1 *.* + ?KFP1 *., ai_ ?KFP1 ,., ]madin ai_ ajpi_ ij _daaemeice ]eoreei rdg_
	enkecdaggt eqd_eio ajm oce RL kmjeecodib oj oce qeiomag ajme]madi 'qDB(-Gi cjiomjg aidhagn+ otke ai_ ceoemjutbjpn hdce+ ]po a ndbidadcaio 3/ % me_pcodji di EiPF cegg iph]em di
	ijmhag oambeodib ja Nemdkcemdi kjndodqe ad]men ran neei an ocet opmi qeiomaggt oj oambeo oce cjhjutbjpn ?KFP1 ,., hdce an jkkjne_ oj rdg_,otke ai_ ceoemjutbjpn aidhagn 'Mie,Uat
	ctkjocagahpn ';WUcrS /,S(+ rcemean di ?KFP1,L? dieecoe_ eh]mtjn+ oce ad]men ca_ a ?LMT?+ Bjiaemmjid oeno+ )N ;/-/4: )) N;/-/0(-Rce _dnomd]podji ja EiPF ceggn ran agnj
	ncaooeme_ akkeamaice+ npbbenodib ocao ?KFP1 hat ]e diqjgqe_ di oce asjiag bpd_aice ja oce aaaecoe_ di ?KFP1 ,., hdce+ rdoc a ndbidadcaio me_pcodji di oce iph]em ja ceggn ajpi_ jigt amjh
	ML ai_ RL _pmdib eh]mtjidc _eqegjkheio-oce geqeg ja oce MTJR kmjbmenndib cap_aggt ojram_n oce ctkjocagahpn '_aoa ijo ncjri(-Rcdn

Qdice ocdn kmjeecodji ajmhn oce asjiag ncaaajg_ ajm oce diomaceme]mag hdbmaodji ja EiPF ceggn 'Wjncd_a eo ag-+ 0884(+ re aiagtne_ oce iph]em ai_ _dnomd]podji ja ocene ceggn di

C03-4

eh]mtjn-, hdce ao C02-4 'i < 1 ajm ]joc beijotken( pndib rcjge hjpio dhhpijnoadidib ajm EiPF ai_ Nemdkcemdi ajggjre_ ]t 2BGQAM cgeamdib ai_ gdbco nceeo hdcmjncjkt 'JQK( ';WUcrS /-(-Gi UR '?KFP1 *.* ( eh]mtjn+ Nemdkcemdi kjndodqe ad]men reme neei oj diiemqaoe oce MB ajmhdib a cjhkgeoe mdib amjpi_ don aioemdjm npmaace ';WUcrS /-O& Q& S(-Gi fijcfjpo hdce '?KFP1 ,., (+ Nemdkcemdi kjndodqe asjin ca_ ]ebpi oj diiemqaoe oce MB+ cjreqem+ ocet ca_ aadge_ oj ajmh a mdib amjpi_ oce ]pg] an neei di UR eh]mtjn ';WUcrS /-P& R& T(-?gojbeocem+ ocene eskemdheion meqeage_ ocao kcamhacjgjbdcag jm beieodc diqagd_aodji ja ?KFP1 gea_n oj a]ijmhag _eqegjkheio ja oce EiPF ai_ jgaacojmt ntnoeh ';WUcrS /-U(+ ndhdgam oj rcao can ]eei _encmd]e_ di IQ ajeopnen 'Qccraiueg,Dpfp_a eo ag-+ 0885: Resedma eo ag-+ 1/0/(-Gi jm_em oj _eoemhdie rceocem oce _eaeco di EiPF cegg hdbmaodji ajpi_ di ?KFP1 ,., hjpne eh]mtjn ran cjmmecoe_ gaoem _pmdib _eqegjkheio+ re kemajmhe_ dhhpijagpjmenceice eskemdheion ajm EiPF di a_pgo ?KFP1 *.* ai_ ?KFP1 ,., hdce 'i < 6 ajm eacc bmjpk+ ;WUcrS /.( ai_ ajpi_ _ecmeane_ EiPF dhhpijmeacodqdot ao oce geqeg ja oce jmbaiph qancpgjnph gahdiae oemhdiagdn 'MTJR: ;WUcrS /. O-R(+ rceme oce haejmdot ja EiPF iepmjin ame ijmhaggt gjcaoe_+ ai_ di oce he_dai ehdieice ja oce ctkjocagahpn ';WUcrS /. S-V(+ rcdcc dn oce kmjeecodji ndoe ja iepmjei_jcmdie EiPF ceggn-Ue ieso cjpioe_ oce iph]em ja EiPF,kjndodqe dn npbbenodqe ja a _eaeco di oce hdbmaodji ja EiPF ceggn di ?KFP1 ,., hdce+ an do can ]eei mekjmoe_ ocao oce adiag aiaojhdcag kjndodjidib ja EiPF ceggn dn gdife_ oj oce odhdib ja oce didodaodji ja ocedm hdbmaodji 'Hanjid eo ag-+ 1//8(-;WUcrS /.

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  ]eggdib ja EiPF di a_pgo rdg_ otke ai_ ?KFP1 ,., hdce 'O-V(-Rce haejmdot ja EiPF cegg ]j_den ame gjcaoe_ ao oce geqeg ja oce jmbaiph qancpgjnph gahdiae Mqamdai cdnojgjbt ja ?KFP1 _eadcdeio aidhagn ncjre_ a]ijmhagdoden npbbenodqe ja ai aijqpgaojmt kceijotke+ rdoc oce kmeneice ja aerem kjno,jqpgaodji cjmkjma gpoea+ ai_ accphpgaodji ja kmeiomag ai_ nhagg aiomag ajggdcgen an cjhkame_ oj rdg_,otke aidhagn 'NL 8/+ i

	2(. 6BH WnQrSOaSa GC11 QSll mWUrObWon dWO bVS 6BHG,)7BEG1P bdqei oce di qdqj eaaecon ja ?KFP1 diqagd_aodji ji EiPF iepmjiag hdbmaodji+ re njpbco oj
	aWUnOllWnU pObVeOg _eoemhdie rceocem ?KF ran a kmj,hjodgdot aacojm ajm EL00 ceggn-Sndib omainregg annatn ;WUcrS //(
	';WUcrS //R(+ re ncjre_ ocao mecjh]diaio cphai ?KF ran a]ge oj ndbidadcaiogt dicmeane oce
	oemhdiagdn 'MTJR( di ]joc ?KFP1 *.* ai_ ?KFP1 ,., hdce+ cjreqem oce iph]em ja cegg ]j_den ajpi_ di ?KFP1 ,., aidhagn dn me_pce_ 'Orroea Q& R(-'W( Opaiodoaodji ja oce ojoag EiPF kjkpgaodji meqeage_ ij _daaemeice ]eoreei rdg_ otke '555-8 ± 23-2/( ai_ ?KFP1 *., '502-0 ± 22-26( hdce cjreqem ?KFP1 ,., hdce caqe aerem '3/6-6 ± 16-14( EiPF iepmjin ')N;/-/4+ )) N;/-/0+ 0rat ?LMT?+ Bjiaemmjid kjno cjc oeno+ i < 6 ajm agg bmjpkn(-EiPF ceggn kmjeeco ocedm iemqe oemhdiagn oj oce he_dai ehdieice 'KC(+ rceme a me_pcodji di oce ad]me _eindot dn j]nemqe_ di ?KFP1 ,., hdce cjhkame_ oj rdg_ otken 'S-V(-?n eskecoe_ rdoc a _eadcdeict di EiPF diiemqaodji+ oce aehage Apmmeiogt+ a cjinoaio 8/,_atn haodib kmjojcjg dn jibjdib oj _eoemhdie rceocem ?KFP1 ,., hdce agnj caqe dhkadme_ aemodgdot 'di_dcaoe_ ]t a ndbidadcaio _egat di ocedm admno gdooem+ aerem gdooemn ai_ aerem kpkn kem gdooem kmj_pce_ jqem a 2,hjioc kemdj_(-Ue ieso rji_eme_ rceocem oce _eqegjkheioag gjnn ja aaaemeio kmjeecodji amjh jgaacojmt neinjmt Rce haidkpgaodji ja oce EiPF hdbmaojmt ntnoeh ai_ apicodjiag nop_den ji ocene iepmjin caqe ]eei ccaggeibdib ]ecapne ja ocedm gdhdoe_ iph]em '7// di mj_eion( ai_ aiaojhdcag _dnkemnag agjib ocedm hdbmaojmt mjpoe-Rce beiemaodji ja dhhjmoagdne_ EiPF iepmjin 'EL00 ai_ ER0, 6 cegg gdien9 Keggji eo ag-+ 088/: Pa_jqdcf eo ag-+ 0880( can kemhdooe_ oce nop_t ja menkecodqegt dhhaopme hdbmaojmt ai_ haopme kjno,hdbmaojmt EiPF iepmjin-Gi kamodcpgam+ EL00 ceggn _dnkgat mehamfa]ge hjodgdot di qdomj+ ai_ caqe ]eei pne_ oj diqenodbaoe oce hjgecpgam hjodgdot ja EL00 ceggn ao agg oenoe_ _jnen '4/ ib.hJ9 4/-0 ± 6-1 ceggn kem adeg_+ N ; /-/4: 0// ib.hJ 33-1 ± 6-3 ceggn kem adeg_+ N ; /-/4: 14/ ib.hJ 45-4 ± 7-/ ceggn kem adeg_+ N ; /-/0: i < 1/ ajm agg( cjhkame_ oj cjiomjgn 'nemph amee he_dph+ QDK 00-7 ± 2-5 ceggn kem adeg_+ i < 01: ;WUcrS /R(-Ue ieso diqenodbaoe_ rcdcc mecekojm cjhkges ran melpdme_ ajm ?KF,_ekei_eio cegg hdbmaodji di EL00 ceggn-Rcdn ran accdeqe_ ]t oambeoe_ fijcf_jri ja otke,0 ai_ otke,1 ?KF mecekojmn ?KFP1 ,.< 2 kem beijotke: ;WUcrS /.X(-iepmjin 'MQL( di ?KFP1,ipgg hdce cjpg_ menpgo di oce ctkjkganda ai_.jm _dnmpkodji ja oce heccaidnhn cjiomjggdib oce _dmecodjiag hdbmaodji ja EiPF iepmjin ai_ oj nce_ gdbco ji oce pndib a ndPL? ndgeicdib akkmjacc-Qdgeicdib eaadcdeict ran admno annenne_+ ncjrdib ocao ndPL?
	]djccehdcag kaocratn ehkgjte_ ]t EiPF ceggn 'Aamd]jid eo ag-+ 1//6: Edacj]did eo ag-+ 1//7: omainaecodji ran a]ge oj me_pce ]t 7/% oce hPL? eskmenndji ja oce oambeo mecekojm beien
	Kenndia eo ag-+ 1/00(-
	Rj annenn rceocem EL00 ai_ ER0,6 ceggn eskmenne_ oce hjgecpgam haccdiemt oj menkji_ oj
	?KF nodhpgaodji+ PR,NAP aiagtndn ran cammde_ jpo oj qemdat oce eskmenndji ja ?KF mecekojmn
	';WUcrS //O(-Mpm _aoa ncjr ocao EL00 ceggn eskmenn ?KFP1+ ?cqP0+ BKNP0a ai_ BKNP0]+ '4/ ib.hJ( ran a]ge oj egdcdo a ndbidadcaio dicmeane di EL00 cegg hjodgdot '25-6 ± 1-5 ceggn kem
	rcemean kjno,hdbmaojmt ER0,6 ceggn eskmenn agg mecekojmn esceko BKNP0] ';WUcrS //O(-Rcene adeg_+ i < 20+ Impnfag,Uaggdn oeno ajggjre_ ]t Bpii'n hpgodkge cjhkamdnji oeno( cjhkame_ oj
	menpgon di_dcaoe ocao ?KFP1.BKNP0] ndbiaggdib dn a cagghamf ja hdbmaojmt EiPF iepmjin ceggn eskjne_ oj QDK agjie '06-3 ± 1-1 ceggn kem adeg_+ i < 32(-Qdgeicdib ja ?cqP0 '21-1 ± 2-1
	ai_ npbbeno ocao ?KF cjpg_ he_daoe a _daaemeio ]djgjbdcag menkjine di hdbmaojmt ai_ kjno, ceggn kem adeg_+ i < 8(+ BKNP0a '36-1 ± 2-/ ceggn kem adeg_+ i < 8( jm JLA PL? '18-0 ± 1-4 ceggn
	dhhpijkjndodqe iepmjin di bg cjpg_ ]e capne_ ]t _eadcdeio aaaemeio MQL kmjeecodjin-Nmeqdjpn hdbmaojmt EiPF iepmjin _ekei_dib ji _daaemeiodag mecekojm cjhkgesen eskmenne_ ocmjpbcjpo kem adeg_+ i < 23( _d_ ijo aaaeco oce EL00 menkjine oj ?KF omeaoheio-Gi cjiomano+ fijcf_jri
	nop_den caqe di_ee_ _ehjinomaoe_ ocao _eaaaemeioaodji ja MQL kmjeecodjin oj oce KMB gea_ oj _eqegjkheio-ja ?KFP1 '0/-5 ± /-8 ceggn kem adeg_+ i < 10( ai_ BKNP0] '3-5 ± 0-2 ceggn kem adeg_+ i < 10(
	a hamfe_ _ecmeane di oce iph]em ja RF,eskmenndib iepmjin di oce bg 'Bafem eo ag-+ 0872: La_d menpgoe_ di ndbidadcaiogt me_pce_ EL00 cegg hjodgdot di menkjine oj ?KF 'Kjcf qn-?KFP1
	?codqaodji ja oce K?NI kaocrat can ]eei kmeqdjpngt annjcdaoe_ rdoc dicmeane_ EL00 cegg
	eo ag-+ 0870( ndPL?+ N ; /-/0: Kjcf qn-Bhkm0] ndPL?+ N ; /-/0-Impnfag,Uaggdn oeno ajggjre_ ]t Bpii'n
	hjodgdot 'Kenndia eo ag-+ 1/00: Faiccaoe eo ag-+ 1/01(-Feme re ajpi_ ocao ?KF+ ao
	hpgodkge cjhkamdnji oeno(-Rcene _aoa di_dcaoe ocao oce ?KF dicmeane_ EL00 cegg hjodgdot qda
	cjiceiomaodjin kmeqdjpngt mekjmoe_ oj ]e apicodjiag di jocem cegg gdien 'Eammeg eo ag-+ 1/05(+
	ai ?KFP1. BKNP0] ndbiaggdib-
	ndbidadcaiogt dicmeanen oce kcjnkcjmtgaodji ja CPI0.1 di EL00 ceggn rdocdi aer hdipoen ai_ di

, hdce caqe agoeme_ jqamdai hjmkcjgjbt+ rdoc a _ecmeane di oce iph]em ja cjmkjma gpoea 'X(-'Y& l( Gi UR hdce+ RF eskmenndji dn cjiadie_ oj oce bgjhempgam gatem rceme dhhpijkjndodqe ceggn ai_ ad]men ame rd_egt ajpi_+ cjreqem+ ocdn eskmenndji dn hamfe_gt me_pce_ di ?KFP1 ,., hdce-'W( _aoa ncjri an heai ± QCK-i < 6+ ) N ;/-/4+

)) N ;/-/0 ]t Mie,rat ?LMT? ajggjre_ ]t Bjiaemmjid Njno cjc oeno-?]]meqdaodjin9 MTJR+ jmbaiph qancpgjnph ja oce gahdia oemhdiagdn: KC+ he_dai ehdieice: 2T+ ocdm_ qeiomdcge: ED+ Emaadai ajggdcge: ?+ aiomag ajggdcge: N?+ kmeaiomag ajggdcge: Q?+ nhagg aiomag ajggdcge: AJ+ cjmkpn gpoeph: ?o+ aomeodc ajggdcge: KMB+ hadi jgaacojmt ]pg]: ?MB+ accennjmt jgaacojmt ]pg]: bg+ bgjhempgam gatem: jkg+ jpoem kgesdajmh gatem: bm+ bmaipgam gatem-jgaacojmt bgjhempgd-Nmeqdjpn nop_den caqe _ehjinomaoe_ ocao di oce hadi jgaacojmt ]pg] 'KMB(+ jigt oce bgjhempgam gatem 'bg( eskmennen otmjndie ct_mjstgane 'RF(+ oce enneiodag maoe,gdhdodib eiuthe diqjgqe_ di oce ntiocendn ja _jkahdie amjh J,otmjndie 'Faganu eo ag-+ 0870(-Ajindnoeio rdoc ocene mekjmon+ di oce KMB ja ?KFP1 UR hdce+ RF,dhhpijkjndodqe iepmjin reme j]nemqe_ hadigt di oce bg ';WUcrS /.Y(-RF,dhhpijkjndodqe iepmjin reme agnj ajpi_ npmmjpi_dib oce bgjhempgd+ ai_ nomjibgt noadie_ RF,dhhpijkjndodqe iemqe ad]men reme rd_enkmea_ di oce bg ';WUcrS /.Y(-Der RF,dhhpijkjndodqe ceggn reme j]nemqe_ di oce KMB ja ?KFP1 -.-cjhkame_ rdoc UR hdce+ rcdge RF iemqe ad]men reme hamfe_gt me_pce_ di oce bgjhempgd ja ?KFP1 -.-';WUcrS /.l(-Rcene _aoa npbbeno ocao oce _ecmeane di oce iph]em ja RF, a _jne,_ekei_eio haiiem ';WUcrS // P-Q(-Kjmejqem+ ndice ?KF can ]eei kmeqdjpngt ncjri oj di_pce hdbmaodji ja ?KFP1,eskmenndib ceggn amjh oce cjegjhdc ekdocegdph dioj oce Kpggemdai _pco heneiccthe 'Xcai eo ag-+ 1//5( ai_ ';WUcrS //S(+ cjhkame_ oj hjcf omainaecoe_ ceggn-Iijcf_jri ja di_dqd_pag ?KF mecekojmn ge_ oj _dnodico hjodgdot menkjinen ja EL00 ceggn oj ?KF nodhpgaodji ';WUcrS //T(-?n ncjri a]jqe ';WUcrS //R(+ ocdn _jne ja mecjh]diaio ?KF

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	?KF mecekojmn ame eskmenne_ ]t oce dhhjmoagdne_ hpmdie EiPF cegg gdien EL00 ai_
	ER0,6 an _eoemhdie_ ]t lPR,NAP+ _aoa ijmhagdne_ oj EL00 eskmenndji 'O(-EL00
	ceggn menkji_ oj ?KF omeaoheio ]t dicmeandib oce kcjnkcjmtgaodji ja K?NI di ]joc a
	_jne 'P( ai_ odhe 'Q( _ekei_eio haiiem+ npbbenodib ocdn kaocrat dn acodqe di ocene ceggn
	i < 4-Csjbeijpn ?KF dn a]ge oj dicmeane oce hjodgdot ja EL00 ceggn pndib a omainregg
	hjodgdot annat+ i < 00 ajm QDK+ i < 07 ajm agg jocem bmjpkn 'R(-Gi jm_em oj _eoemhdie
	rcdcc ?KF mecekojmn reme dhkjmoaio ajm he_daodib ocdn hjodgdot eaaeco+ oce eskmenndji
	ja eacc kjoeiodag mecekojm ran fijcfe_ _jri pndib oambeoe_ ndPL?n-'S(-Cacc ndPL?
	ran a]ge oj me_pce oce eskmenndji ja don oambeo PL? rdoc ij eaaeco ji oce geqeg ja gjib
	iji,cj_dib PL? 'JLA( i < 2 'S(-Csjbeijpn ?KF ran a]ge oj di_pce dicmeane_
	hjodgdot di cjiomjg+ ?cqP0+ BKNP0a ai_ JLA ndPL? omeaoe_ bmjpkn-ndPL? he_daoe_
	fijcf_jri ja ?KFP1 ai_ BKNP0] menpgoe_ di ij ccaibe oj oce hjodgdot ja EL00

ceggn cjhkame_ oj cjiomjg rcei omeaoe_ rdoc ?KF-'O& P( Baoa ncjri an heai ± QCK+ ) N ;/-/4+ )) N ;/-/0+ )))N ;/-//0 ]t 0rat ?LMT?+ Bpiieoo'n kjno cjc oeno oj cjhkame hpgodkge bmjpkn-'R-T( Baoa ncjri an he_dai ± dioemlpamodge maibe+ a < ndhdgam bmjpkn an _eoemhdie_ ]t Impnfag,Uaggdn oeno ajggjre_ ]t Bpii'n hpgodkge cjhkamdnji oeno-;WUcrS /

0( 6BH Wa cnOPlS bo rSaQcS WmmorbOlWaSR GnGH QSlla Trom IC;i WnRcQSR OpopboaWa

	an _ahabdib oj kmjoedi apicodji ai_ jccpm di cjinemqe_ mend_pen+ npbbenodib ocene qamdaion gdfegt
	dhkaco kmjoedi apicodji 'IOPlSa 3 OnR 1*(-
	Rj annenn oce ]djgjbdcag acodqdot ja oce qamdaion+ re oenoe_ ocedm hjodgdot,di_pcdib kmjkemoden ji
	EL00 ceggn ';WUcrS /1P(-Ue ajpi_ ocao adqe ja oce nds oenoe_ hpoaion reme genn eaaecodqe ao
	kmjhjodib EL00 hjodgdot an cjhkame_ oj UR ?KF ';WUcrS /1P(-Ue ieso noamoe_ oj diqenodbaoe
	oce ?KF necmeojmt cakacdot ja AMQ,6 ceggn omainaecoe_ rdoc 2 _daaemeio ?KF qamdaion
	'k-Egp05/?nk+ k-Tag01Egt+ k-?nk177Egp(+ ocao me_pce EL00 cegg hjodgdot-Ma ocene qamdaion+
	jigt oce ?KF k-?nk177Egp+ gjcaoe_ di oce adaoc esji ja oce L,oemhdiag _jhadi+ ncjre_
	ndbidadcaiogt me_pce_ ?KF necmeodji di qdomj
	Gj_d_e ame ga]egge_ L

'O( EL00 ceggn cpgopme_ di QDK ncjr gjr geqegn ja akjkojodc ai_ iecmjodc ceggn ocao dn cjhkama]ge oj EL00 ceggn cpgopmen rdoc 0//ib.hJ ja ?KF-RLDα omeaoheio capnen ndbidadcaio dicmeanen di oce kmjkjmodji ja akjkojodc ai_ iecmjodc ceggn an can ]eei kmeqdjpngt mekjmoe_ ajm jocem cegg gdien-Aj,cpgopme ja RLDα ai_ 0//ib.hJ ?KF dn pia]ge oj Gicmeane EL00cegg npmqdqag an cjhkame_ oj RLDα omeaoheio agjie-'P( oce nahe kaooemi ran j]nemqe_ ajm ER0,6 ceggn-?kjkojodc ceggn ndibge ga]egge_ rdoc ?iiesdiT ame ga]egge_ ?+ iecmjodc ceggn _jp]ge kjndodqe ajm ?iiesdiT ai_ Nmjkd_dph ';WUcrS /1Q(-Rcene menpgon cjiadmh ocao oce d_eiodade_ ?KF qamdaion ame di_ee_ gjnn,ja,apicodji hpoaodjin+ npbbenodib a kaocjbeidc mjge di AFF kaodeion ai_ kjdio ojram_n a mjge ajm ?KF di EiPF iepmjiag hdbmaodji-

IOPlS

34 GSnobgpSa& TcnQbWonOl prSRWQbWon OnR QlWnWQOl WnTormObWon oT KH proPOnRa VOrPocrWnU 6BH dOrWOnba( IOPlS 1*4 GSnobgpSa& TcnQbWonOl prSRWQbWon OnR QlWnWQOl WnTormObWon oT 8HH proPOnRa (normOl aSnaS oT amSll or OPaSnQS oT TormOl bSab) VOrPocrWnU 6BH OnR 6BHG, dOrWOnba( ;WUcrS /1( ;cnQbWonOl dOlWRObWon oT 6BH mcbObWona WRSnbWTWSR Wn 8HH OnR KH pObWSnba Ucjge

	± QB-i =6 ajm agg bmjpkn+ ) N ;/-/4+ )) N ;/-/0+ ))) N ;/-//0 ]t Impnfag,Uaggdn oeno
	ajggjre_ ]t Bpii'n hpgodkge cjhkamdnji oeno-Gi jm_em oj qagd_aoe rceocem oce hpoaoe_
	?KF dnjajmhn reme omaingaoe_ ai_ necmeoe_+ ai CJGQ? ajm c?KF ran kemajmhe_ ji oce
	cji_dodjie_ he_dph ja omainaecoe_ AMQ,6 ceggn 'Q(-Qeqemag ja oce hpoaoe_ ajmhn ja ?KF

esjhe nelpeicdib ja 6/ IQ ai_ 32 iAFF kmj]ai_n ai_ d_eiodade_ neqemag ceoemjutbjpn hdnneine hpoaodjin di oce ?KF beie ai_ di don mecekojmn di ]joc IQ ai_ iAFF di_dqd_pagn 'O(-Kpoaodjin reme ntiocendne_ ]t oambeoe_ hpoabeiendn ja oce cgjie_ rdg_ otke c?KF nelpeice-Rcene hpoaoe_ ajmhn ja ?KF reme oenoe_ ajm ocedm a]dgdot oj di_pce EL00 cegg hjodgdot qda omainregg annat 'P(-Rce haejmdot ja hpoaoe_ ?KF dnjajmhn reme pia]ge oj di_pce oce nahe geqeg ja hjodgdot an c?KF UR-Baoa mekmeneioe_ an heai _daaeme_ di ocedm geqeg ja necmeodji an _eoemhdie_ ]t CJGQ?+ ]po agg reme _dnodibpdnca]ge amjh oce hjcf he_dph ocao cjioadin ij ?KF-Baoa mekmeneioe_ an he_dai ± dioemlpamodge maibe-) N ;/-/4 ]t Impnfag,Uaggdn oeno ajggjre_ ]t Bpii'n hpgodkge cjhkamdnji oeno-

d'AMH ont entraîné une diminution de la motilité de la cellule GnRH et une diminution de la sécrétion de l'AMH par les cellules COS-7 transfectées, ce qui suggère fortement que ces variantes ont un effet pathogène. Nos résultats mettent en évidence un rôle nouveau pour l'AMH dans le développement et la fonction des neurones de la GnRH et indiquent que l'insuffisance de signalisation AMH contribue à la pathogenèse de la CHH.En résumé, ce travail donne un aperçu de la base moléculaire de la signalisation AMH dépendant dans l'établissement correct du processus migratoire GnRH. En outre, ce travail implique des mutations AMH dans la pathophysiologie de la CHH en cohérence avec le rôle de ce gène dans le bon développement des neurones GnRH et supporte l'idée que les défauts migratoires de la population GnRH sont exclusivement réservés à KS et ne se produisent pas dans les conditions de nCHH.

Development of the vomeronasal & terminal nerves

Whole mount immunostaining of GnRH

Distribution & number of GnRH neurons