Martin Drucker

Aurélie Bak

Jean Luc Macia

Stéphane Blanc

Do viruses sense their vector ?

à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d'enseignement et de recherche français ou étrangers, des laboratoires publics ou privés.

Martin Drucker 1,2 , Aurélie Bak 1 , Jean-Luc Macia 1 , Stéphane Blanc 1 1 Equipe CaGeTE, INRA UMR 385 BGPI, Montpellier, France 2 contact : drucker@supagro.inra.fr

Noncirculative transmission:

… is often thought to be purely mechanical Aphid transmission experiments using protoplasts:

Cauliflower mosaic virus

Circular ds DNA, icosahedral

Turnip mosaic virus

→

  Virus acquisition is not purely mechanical → Ca 2+ signaling pathways are involved in acquisition → TPC1 channels are not involved in virus-vector recognition Aphid transmission of both CaMV and TuMV requires live cells The general Ca 2+ channel blocker lanthanum inhibits transmission Aluminium does not inhibit transmission Gadolinium inhibits transmission of TuMV and maybe CaMV → Other Ca 2+ channels are involved Lin et al. (2005) Biochem BiophysRes Comm 332, 823-830

Aphids? © INRA, UMR 385, 2012 YES! YES! Do viruses sense their vector? Do viruses sense their vector?