Martina Rojnic Kuzman

Simavi Vahip

Andrea Fiorillo

Julian Beezhold

Mariana Pinto Da Costa

Oleg Skugarevsky

Geert Dom

Izet Pajevic

Alma Mihaljevic Peles

Pavel Mohr

Anne Kleinberg

Eka Chkonia

Judit Balazs

William Flannery

Ramune Mazaliauskiene

Jana Chihai

Jerzy Samochowiec

Doina Cozman

Goran Mihajlovic

Lubomira Izakova

Celso Arango

Philip Gorwood

Mental Health Services during the first wave of the COVID-19 pandemic in Europe: Results from the EPA Ambassadors Survey and implications for clinical practice

ou non, émanant des établissements d'enseignement et de recherche français ou étrangers, des laboratoires publics ou privés.

Introduction

The COVID-19 pandemic has led to a worldwide crisis in a variety of sectors, including health, social welfare and society at large. The World Health Organisation (WHO) declared that mental health services should be considered one of the essential health services to be maintained during the COVID-19 health crisis for different population levels [START_REF]Guidelines to help countries maintain essential health services during the COVID-19 pandemic[END_REF], because the pandemic is associated with a significantly increased demand for mental health services [START_REF] Fiorillo | The consequences of the COVID-19 pandemic on mental health and implications for clinical practice[END_REF][START_REF] Moreno | How mental health care should change as a consequence of the COVID-19 pandemic[END_REF].

For example, up to a third of persons who develop COVID-19 exhibit neuropsychiatric manifestations directly due to the infection itself (4) and significant numbers of patients are presenting with deterioration in their existing mental disorders, along with many with new anxiety and mood disorders triggered by the pandemic and its economic and social consequences [START_REF] Czeisler | Mental health, substance use, and suicidal ideation during the COVID-19 pandemic: United States, June 24-30, 2020[END_REF][START_REF] Fiorillo | Effects of the lockdown on the mental health of the general population during the COVID-19 pandemic in Italy: Results from the COMET collaborative network[END_REF][START_REF] Daly | Longitudinal changes in mental health and the COVID-19 pandemic: evidence from the UK Household Longitudinal Study[END_REF]. People with chronic mental disorders have increased mortality risk factors, including smoking, metabolic syndrome and hypertension and may be at increased COVID-19 infection risk [START_REF] Zhou | Clinical course and risk factors mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study[END_REF][START_REF] Taquet | Bidirectional associations between COVID-19 and psychiatric disorder: retrospective cohort studies of 62'354 COVID-19 cases in the USA[END_REF]. Importantly, frontline medical staff suffers from higher levels of burn out [START_REF] Zhang | Mental Health and Psychosocial Problems of Medical Health Workers during the COVID-19 Epidemic in China[END_REF][START_REF] Dong | The social psychological impact of the COVID-19 pandemic on medical staff in China: A cross-sectional study[END_REF].

Apart from an increased demand for mental health services for different levels of population, the pandemic has also brought the need for fast and flexible adaptations in the organization of mental health services to respond to these increased demands. There was also a need to maintain mental health care for all persons currently treated for pre-existing mental health disorders, who need continuous and un-interrupted medical care, for example regarding substitution therapy or long acting injectable medications. Moreover, psychiatric facilities with patients hospitalized due to chronic psychiatric conditions constituted particularly vulnerable units, due to greater potency of the virus spreading [START_REF] Shah | Focus on mental health during the coronavirus (COVID-19) pandemic: Applying learnings from the past outbreaks[END_REF]. However, despite these requirements, during the first wave of the COVID-19 pandemic, psychiatric services were reduced to emergency care only in most countries, with the few remaining services which almost spontaneously shifted from the traditional face-to-face services to the remote services (from telephone services to the use of different video platforms), as the only possible option [START_REF]The impact of COVID-19 on mental, neurological and substance use services: results of a rapid assessment[END_REF].

Response of the (inter)national psychiatric associations to COVID-19 pandemics in March 2020

With high demands for mental health services together with a dramatic increase of the number of patients with COVID-19 requiring all health resources to be directed to the prevention of the pandemic and the organization of health care for COVID-19 patients, different solutions by national policy makers were searched for within different countries.

In line with WHO recommendations [START_REF]Guidelines to help countries maintain essential health services during the COVID-19 pandemic[END_REF], mental health national and international professional associations across Europe issued recommendations during the first peak period of COVID-19 pandemic (in March 2020) for the organization of mental health services. However, despite those efforts, disruption in mental health service delivery was observed in most countries [START_REF]The impact of COVID-19 on mental, neurological and substance use services: results of a rapid assessment[END_REF].

According to the websites of the European and the World Psychiatric Associations, the majority of European national psychiatric associations provided a series of guidance documents (https://www.europsy.net/epa-resources-for-covid-19/ and https://www.wpanet.org/covid-19-resources?lang=de) which defined the basic organisation of psychiatric care in their countries [START_REF]COVID-19 Resource Centre[END_REF][START_REF]World Psychiatric Association Coronavirus (COVID-19) Mental Health Resources[END_REF]. The topics of these documents, as well as the major recommendations included in those documents, were relatively similar across different professional associations, as well as across the guidelines issued by the organisations of patients and their families active in Europe (The Global Alliance of Mental Illness Advocacy Networks-Europe GAMIAN-Europe and EUFAMI). In general, and in line with the WHO recommendations (1), all stressed the need to maintain the care for persons with pre-existing mental health care and comply with epidemiological measures; all stressed psychosocial consequences of the restrictive public measures to general population and frontline medical workers, and all recommended organisational changes in the direction of offering remote instead of face-to-face services. These recommendations are summarised in Table 1. Responses were collected from July to August 2020, using an online questionnaire.

Psychiatrists who are either individual members of the EPA, attendees of the congresses of the EPA or the members of the EPA Council of National Associations member societies and early career psychiatrists (ECP) were invited to participate by sending them an invitation with a link to the online questionnaire. Responses were collected from July 2020 to August 2020.

The survey was open to all clinicians in mental health, and in this regard, do not pretend to have any exhaustivity nor representativity. We initially sent an invitation email to the EPA list of past participants (who agreed to be contacted), which means around 10,000 e-mail addresses. We contacted all National Psychiatric Associations (N=44) and the Council (ECP)

early career psychiatrists (N=1) who were asked to distribute the invitations among the members of their associations.

Nine hundred forty responses were collected, with 857 participants practicing in Europe.

Therefore, only responses from the 857 participants practicing in Europe were included in the final analyses. Among them, 56% of respondents were female (N=480), 38.8% (N=333) were below 40 years of age, whereas 28.9% (N=419) were aged 41-60 and the rest (32.3%) were aged over 60. Most responders were psychiatrists (75.5%, N=647) followed by trainees in psychiatry (13.3%, N=117), other mental health professionals (including psychologists, social workers and nurses) (5.7%, N=49), and users of mental health services (0.8%, N=7).

Access to consultations with psychiatrists

We categorized countries to three regions according to EuroVoc. Before the analyses, we weighed our sample according to the total number of psychiatrists working in each country, so that the structure of the sample had the same structure as the targeted population. We provide both crude and weighted estimates. For each region, we calculated the median and interquartile range (IQR) of number of patients before pandemic and during the April 2020, number tested, percentage tested out of all those seen during April, and the estimated percentage affected with SARS-CoV-2 out of all patients seen during April 2020. For the difference between the number of patients seen before the pandemic and during April 2020, we calculated the median of absolute differences (∆) with the 95% Bonett-Price confidence interval (CI), statistical significance of the differences using the Wilcoxon rank-sum (Mann-Whitney U) test, and the percentage change (∆%) relative to the number of patients before the pandemic. To test the significance of differences in medians between the three regions, we used the quantile regression. As the maximum missing data for any variable was ≤ 1%, we excluded these cases from specific analyses (pairwise deletion).

We controlled for the inflation of false positive results caused by multiple testing by using the Benjamini-Hochberg procedure with a false positive rate set at FDR < 5%. We calculated all confidence intervals at 95% level and set the two-tail significance rate at 0.05. We performed While 857 participants responded, 236 had no data on the number of patients before the pandemic, 12 more declared that they had zero patients before and during April as being tested or infected, and one participant declared no patients seen before the pandemic, nor during April. The final sample size was therefore 608, consisting only of participants who practice in Europe, and who had at least one patient monthly before the pandemic.

In the weighted total sample, the median number of patients seen monthly by one psychiatrist before the pandemic was 50 (IQR 30-100), and the difference between the three regions were not significant ( FDR < 5%), but it was also significant in the Central and Eastern Europe (∆ = -25 compared to the Western Europe; 95% CI -28; -3; p = 0.025; FDR < 5%). We have not observed any significant difference between the three regions in the number of tested patients, the percentage tested out of all patients seen during April, and the percentage infected by SARS-CoV-2 out of all those seen during April (Table 2). Data are presented as median number of patients if not stated otherwise Abbreviations: n, number of participants; M, median; IQR, interquartile range; ∆, median of differences between the number of patients before pandemic and during April 2020; CI, Bonett-Price confidence interval for median; p, statistical significance of the absolute difference calculated using Wilcoxon rank-sum (Mann-Whitney U) test; ∆%, median of relative differences in number of patients calculated as the number of patients (Aprilbefore)/before * FDR <5% † There were 4 (0.7%) missing data for number of patients during April 2020; 5 (0.8%) for number tested; 6 (1.0%) for number infected ‡ Samples were weighted for the total number of psychiatrists in particular countries

Although it is possible that this decrease in the number of visits resulted from public measures (such as physical distancing, quarantine and call for stay at home except in emergencies) which were in place in most countries during the study period and lower number of patients seeking psychiatric help at that time, this may also reflect the disruption of mental health services contrary to the recommendation of the WHO (1) and the recommendations of psychiatric associations [START_REF]COVID-19 Resource Centre[END_REF][START_REF]World Psychiatric Association Coronavirus (COVID-19) Mental Health Resources[END_REF]. Indeed, the WHO survey performed in 130 countries which used responses collated by national ministries of health, found that in most countries, disruption in the organisation of outpatient and community mental health patients with drug addiction and for suicidal patients), psychotherapy and child and adolescent psychiatry were most disrupted [START_REF]The impact of COVID-19 on mental, neurological and substance use services: results of a rapid assessment[END_REF].

Interestingly, the number of psychiatric patients being tested for COVID-19 was quite low as well as the number of positive cases, without any significant differences between the regions.

(Table 2). While this may reflect a protective effect from social isolation of patients with severe psychiatric disorders, it may not be different from other groups who were aware that they may be at risk of severe COVID-19 forms (for example older adults, people with chronic morbidities, or cancer or compromised immune system). Thus, it is also possible that these figures increased over the following months. However, large population studies in the USA report contrary findings, with persons with pre-existing psychiatric disorders more likely to develop COVID-19 infection [START_REF] Taquet | Bidirectional associations between COVID-19 and psychiatric disorder: retrospective cohort studies of 62'354 COVID-19 cases in the USA[END_REF][START_REF]WHO Coronavirus situation report[END_REF]. While the reasons for this finding are unclear, and in part also explained by the accessibility of the medical care and the overall living conditions and socioeconomic status for the persons with mental illness in America, it would be of interest to examine the dynamics of the rates of patients with psychiatric conditions who are exposed and infected with SARS-CoV-2 and develop COVID-19 over specific phases of pandemic, as it should be considered when planning the organisation of health care for persons with pre-existing mental health problems.

Replacement of face-to-face by remote consultations

In line with the recommendation by the psychiatric associations, in most European countries, face-to-face has been replaced by online consultations, online consultation delivery ranging from 25% to more than 75% of all consultations. However, several differences between countries have been detected. In most of the countries, approximately 50% of services were offered online, but in others, especially Western countries, the percentage of telepsychiatry consultations was significantly higher (Figure 1). Although most national psychiatric associations recommended replacing the traditional face-to-face with online or remote consultations, it seems that most countries lacked infrastructure, IT expertise or legal frameworks for rapid provision of telepsychiatry during the first wave pandemic peak, which may explain the variation of the degree of the implementation across countries. Countries with a number of responses lower than 5 were not shown.

Organization of mental health services for patients

The re-organisation of mental health care services for patients with mental disorders who were infected by SARS-CoV-2 was rather different across Europe. Indeed, we observed a high variation in hospital-based care for persons with COVID-19 and pre-existing mental disorders for these patients in the overall sample, ranging from "general hospitals" (28.8%),

to "psychiatric hospitals" (22.1%), "COVID-19 wards specifically designed for psychiatric patients" (28.4%) and "COVID-19 wards for all patients" (20.7%) (Figure 2). The creation of specialist units for patients with mental health problems who developed COVID-19 may reflect differences between mental health services in Europe in general.

However, it may also reflect the fact that health services in general were struggling in March 2020, and possibly trying out different options, with rapid changes everywhere.

Considering that few national psychiatric associations issued recommendations on the organisation of care for mentally ill patients who developed COVID-19, it is not known whether they were represented in local authorities (for example ministries) responsible for the organisation of health services, and whether they contributed to the decision-making process.

Other factors including the stigma towards psychiatry may be also relevant to care delivery for example resulting in decreased availability of adequate health care for patients with mental illness [START_REF] Winkler | A blind spot on the global mental health map: a scoping review of 25 years' development of mental health care for people with severe mental illnesses in central and eastern Europe[END_REF]. This may be an argument for the organisation of psychiatric care within specialist COVID-19 centres for all patients to guarantee an equal level of care, especially in countries where psychiatric facilities are less equipped with protective equipment, supply of oxygen or have worse sanitary conditions.

This was recognized in some countries (e.g., Croatia) where the national psychiatric associations specifically tackled the problem of stigma in their March 2020 recommendations. It is noteworthy that some national psychiatric associations (e.g., Slovakia) clearly stated that adequate equipment and personnel in psychiatric facilities should be provided before psychiatric wards admitted patients with comorbid acute SARS-CoV-2 infection. This seems especially important considering the increased risk of patients with mental health problems for developing complicated forms of COVID-19 due to the presence of multiple risk factors [START_REF] Czeisler | Mental health, substance use, and suicidal ideation during the COVID-19 pandemic: United States, June 24-30, 2020[END_REF].

In some countries such as France, the guidelines issued by professional associations supported the organisation of COVID-19 units within psychiatric wards, which were adequately equipped with equipment and staff for the safe management of COVID-19, in concordance with the exiting reports from the literature [START_REF] Chevance | Ensuring mental health care during the SARS-CoV-2 epidemic in France: A narrative review[END_REF].

However, organisation of COVID-19 units within psychiatric hospitals may be problematic if these hospitals also include nearby wards for patients with chronic mental illnesses, forensic wards or old age psychiatric units; or with high levels of staff rotating between wards due to very high rate of spread of the SARS-CoV-2 virus once introduced [START_REF] Shah | Focus on mental health during the coronavirus (COVID-19) pandemic: Applying learnings from the past outbreaks[END_REF][START_REF] Xiang | The COVID-19 outbreak and psychiatric hospitals in China: managing challenges through mental health service reform[END_REF]. The impact of different models of service delivery is yet to be determined, therefore it is crucial that all facilities monitor the treatment outcomes for patients with COVID-19 and preexisting mental disorders; and work to prevent the increased morbidity and mortality due to inequitable access to health services.

While service delivery for patients with acute mental health problems who develop COVID-19 may differ due to local circumstances, it is important that ethical principles are followed.

Patients with psychiatric problems should receive the same level of health care for COVID-19, as persons without pre-existing mental disorders. This is especially important since reports from some countries (such as USA) suggest a doubled mortality rate due to COVID-for medical comorbidities, thus highlighting the role of social, behavioural and lifestyle factors in contributing to this profound inequality [START_REF] Taquet | Bidirectional associations between COVID-19 and psychiatric disorder: retrospective cohort studies of 62'354 COVID-19 cases in the USA[END_REF][START_REF]WHO Coronavirus situation report[END_REF].

Cooperation between mental health providers

While an effective fight against pandemic COVID-19 required cooperation at different levels, most participants reported a drop in the quality of cooperation with nurses, general practitioners, psychologists, and family members with whom close collaboration had previously been a good and an integral part of work prior to the pandemic. On the other hand, no significant change was reported in the quality of cooperation with occupational therapists, physiotherapists, pharmacists, policy makers and insurance companies, reflecting the low levels of cooperation reported even before the COVID-19 pandemic (Figure 3).

This reduced or less effective cooperation with policy makers may have adversely influenced effective psychiatric and health service delivery for persons with mental illness as well as the poor implementation of the recommendations issued by the psychiatric associations. For example, good cooperation with policy makers and health care insurance companies may be crucial for introducing legislative and financial coverage for new ways of health care provision, such as telepsychiatry and remote working, or liaison psychiatric care within COVID-19 units (3). Also, good cooperation with general practitioners, nurses and pharmacists may be critical for aspects of service delivery during pandemic times, for example, the organisation of substitute therapy or change long-acting injectable medication especially during periods of lockdown and isolation. Finally, cooperation between psychiatrists and legal experts is needed to assure the human rights of patients [START_REF] Thome | The impact of the COVID-19 outbreak on the medico-legal and human rights of psychiatric patients[END_REF]. Importantly, studies have shown that medical personnel experience increased amounts of insomnia, somatization, anxiety and depression during a pandemic [START_REF] Moser | Years of life lost due to the psychosocial consequences of COVID-19 mitigation strategies based on Swiss data[END_REF][START_REF] Sani | Mental health during and after the COVID-19 emergency in Italy[END_REF]. Thus, good cooperation between health care providers may also have a protective effect for clinicians working with COVID-19 patients, especially when it is difficult to predict a return to normality and the predicted consequences counted as years of life lost (YLL) due to psychosocial consequences of COVID-19 mitigation measures [START_REF] Lu | Psychological status of medical workforce during the COVID-19 pandemic: A cross-sectional study[END_REF][START_REF] Pappa | Prevalence of depression, anxiety, and insomnia among healthcare workers during the COVID-19 pandemic: A systematic review and meta-analysis[END_REF]. Developing a support system at scale, for people affected by mental crises after various disasters, is a challenge for mental health services and requires engagement and support from all mental health care providers [START_REF] Moreno | How mental health care should change as a consequence of the COVID-19 pandemic[END_REF]. European countries which proved effective but within specific local context in countries where this service is not fully implemented yet. There is a need for discussions on all aspects of the use of remote/telepsychiatry and finding ways to optimise implementation across countries [START_REF] Ramalho | Telepsychiatry During the COVID-19 Pandemic: Development of a Protocol for Telemental Health Care[END_REF]. When it comes for the hospital-based care for persons with COVID-19 and pre-existing mental disorders, we detected large differences between countries, in particular regarding access to services (with different level of access and types of consultations), assessment processes, and admission to hospital settings (specific wards for COVID-19 inpatients) for patients with psychiatric disorders. As the effect of these individual solutions on the delivery and quality of health care is not known, it would be of interest to continue to monitor the accessibility of and quality of psychiatric services (for example number of patients, waiting lists, type of services, type of personnel, equipment etc.) based on the real life data and in specific national context, in order to make transparent decision on which services should continue and which should be re-organized.

Conclusions

According to our results, during the pandemics, most participants experienced a drop of the cooperation between different stakeholders including a poor cooperation with policy makers.

Thus, a better cooperation between different levels of health care providers must be guaranteed to assure an efficient and enduring provision of health care services and the implementation of recommendation by the national psychiatric associations in the real-world practice. As we expect the rise in mental health problems during and following the pandemic [START_REF] Moser | Years of life lost due to the psychosocial consequences of COVID-19 mitigation strategies based on Swiss data[END_REF], since the infection with SARS-CoV-2 increases the risk of mental disorders in general population [START_REF] Sani | Mental health during and after the COVID-19 emergency in Italy[END_REF], medical workers [START_REF] Lu | Psychological status of medical workforce during the COVID-19 pandemic: A cross-sectional study[END_REF][START_REF] Pappa | Prevalence of depression, anxiety, and insomnia among healthcare workers during the COVID-19 pandemic: A systematic review and meta-analysis[END_REF] This survey had several limitations. The major limitation is certainly the lack of knowledge on the representativeness of the sample, because of the method of recruitment, as the survey was open to "all clinicians in mental health". In this regard we acknowledge that the sample does not have any exhaustivity nor representativity. Secondly, the overall number of participants is rather low, especially when it comes to the numbers in specific countries.

Finally, the data obtained by the participants are relying on their estimations, based on their everyday clinical practice, rather than accurate number of cases based on national statistics.

Nevertheless, this survey presents data on the functionality of several important mental health services during the first wave of the COVID-19 pandemic in Europe. Although these data are changing inevitably due to the dynamics of the COVID-19 pandemics, they still present a valuable source of information on the development of the first response of mental health systems to the situation. This study also presents how different countries adapted to the disruption of the mental health services in pandemic in the first wave. While the mental health policies might have changed in the second and third waves, the adaptation to the first wave set out some of the important decisions to mental health services organization. Learning from this pandemic experience, from its start, seems crucial for the future. Secondly, we gathered data from many countries in Europe, including those from which we lack data when it comes to the organization of mental health in Europe. This information will be used by the European Psychiatric Association and Council of National Psychiatric Associations in coordinating the exchange of learning, facilitating wider implementation of good clinical practice throughout Europe and supporting all European authorities, organizations and mental health workers in their relevant needs.

Financial support

The work was funded by the European Psychiatric Association.

Tables and Figures

Table 1. Countries with a number of responses lower than 5 were not shown.

  statistical data analyses using StataCorp 2019 (Stata Statistical Software: Release 16. College Station, TX: StataCorp LLC).

Figure 1 .

 1 Figure 1. Estimation of the percentage of on-line services provided instead of face-to-face

Figure 2 .

 2 Figure 2. Predominant model of service for persons with pre-existing mental health problems

  Another option recommended by national associations (e.g. Turkey) includes different steps for psychiatric patients tested positive: giving priority to safe provision of the maximum possible quality psychiatric services using close and continuous consultation and liaison with COVID-19 services of general hospitals; and providing at least one fully equipped (physical needs, personal protective equipment and staffing) COVID-19 psychiatry unit for each region of the country dedicated to care for acutely ill psychiatric COVID-19 positive patients. Due to established risk factors and high vulnerability to complicated forms of COVID-19 in older age or dementia patients, wards for old age psychiatry should be kept separate.

Figure 3 .

 3 Figure 3. Cooperation between health care providers during April 2020 compared to the

  National psychiatric associations responded rapidly to the first wave of the COVID-19 pandemic with most issuing recommendations already by March 2020 and were markedly consistent across Europe in terms of topics and overall recommendations. Nevertheless, contrary to the recommendations of the WHO (1) and the efforts of the national psychiatric associations[START_REF]COVID-19 Resource Centre[END_REF][START_REF]World Psychiatric Association Coronavirus (COVID-19) Mental Health Resources[END_REF], we detected significant changes in mental health care service delivery in April 2020, considering a significant drop in the number of outpatients visits across Europe countries, probably indicating the disruption of psychiatric services across Europe, and the effects on the lock down measures contributing to the decrease in the number of patients seeking psychiatric help on the other side.With a significant reduction of in-person consultations mainly due to lockdown measures, most countries shifted, to varying degrees, towards online or remote psychiatric care as one of the only safe options available at the time. This might represent a significant barrier specifically for vulnerable, multi-problem patients often with less means to or competencies to access to digital communication. It is reasonable to expect that the use of telepsychiatry and remote consultation will increase further given the potential duration of the pandemic. As the equipment and legislation supporting the implementation of remote services may be lacking in many European countries, future efforts should focus on implementation research and implementation of the new remote services based on the models established in other

Figure 1 .

 1 Figure 1. Estimation of the percentage of on-line services provided instead of face-to-face

Figure 2 .

 2 Figure 2. Predominant model of service for persons with pre-existing mental health problems

Figure 3 .

 3 Figure 3. Cooperation between health care providers during April 2020 compared to the

Table 1 .

 1 Recommendations on mental health care during the COVID-19 pandemic issued by European psychiatric associations in March 2020

	Topic

Changes of mental health services in Europe in April 2020

	Associations member societies and early career psychiatrists (ECP). They were offered to
	become "EPA Ambassadors" and to participate in EPA surveys to rapidly obtain Europe-
	wide information regarding psychiatric care and services. The Ambassadors agreed to collect
	important information in their own country, to inform stakeholders at the European level,
	therefore facilitating faster actions and adaptations of mental health policies in Europe. The
	questionnaire focused on the organization of mental health care for patients with pre-existing
	mental health problems during the first wave European COVID-19 pandemic peak (April
	2020) and included questions on the access to care (the estimation on the number of patients
	treated, estimation of the number of patients tested and positive for COVID-19), modalities
	of visits (the estimation on the number of patients who were visited using remote services
	instead of face to face visits)
	To assess psychiatric care throughout time periods, the European Psychiatric Association
	(EPA) approached psychiatrists working in Europe, who are either individual members of the
	EPA, attendees of the congresses of the EPA or the members of the EPA Council of National

, the type of planned facilities for patients with mental health problems and COVID-19 and the level of satisfaction with the collaboration between different stakeholders in organization of mental health care. Questions also inquired data on sociodemographics (age, gender, duration of mental health care practice, position, type of work and place of work).

Table 2 )

 2 . The median number was the same in Central and Eastern Europe than in Northern and Western Europe, the latter being used as the reference region (∆ = 0;

95% CI -38; 38; p > 0.999; FDR > 5%). In Southern Europe, the median number of patients was larger than in Northern and Western Europe, but the difference was not significant (∆ = 30; 95% CI -6; 66; p = 0.101; FDR > 5%). During April 2020 the number of patients decreased by 10 (95% CI -15; -5; p<0.001; FDR <5%), corresponding to 25% less median number of patients monthly. The relative decrease in the number of patients during April was significantly different between the three European regions. The decrease was the largest in Southern Europe (∆ = -42 compared to the Western Europe; 95% CI -64; -20; p < 0.001;

Table 2 .

 2 Estimation of numbers of patients with mental health problems seen by psychiatrists

		During	Difference in the number		Percentage
	Before	April	of	Number	tested	Percentage
	pandemic	2020 †	patients during the first	tested	out of all in	infected
			lockdown		April

  was observed, while the hospital-based services remained fully open in around 70% of countries. Services for substance use disorders were the most affected. Specific interventions for old age psychiatry, promotion and prevention services (including those for

		n M	(IQR) M	(IQR) ∆	(95% CI)	p	∆% M (IQR) M (IQR) M	(IQR)
	Crude sample
	Whole Europe	60 8	80	(40-150)	40	(20-80)	-20	(-25; -15)	<0.001* -40 3	(0-10)	7 (0-25)	1	(0-10)
	Northern and Western	16 8	50	(30-100)	40	(20-70)	-5	(-10; -0)	0.044* -13 2	(0-7)	4 (0-20)	1	(0-10)
	Southern	19 7	10 0	(50-200)	45	(20-98)	-40	(-57; -23)	<0.001* -54 4	(0-10)	7 (0-31)	3	(0-13)
	Central and Eastern	24 3	80	(35-150)	30	(20-80)	-20	(-27; -13)	<0.001* -40 3	(0-10)	10 (0-31)	0	(0-6)
	Weighted
	sample ‡
	Whole Europe	60 8	50	(30-100)	40	(20-70)	-10	(-15; -5)	<0.001* -25 3	(0-5)	7 (0-25)	0	(0-12)
	Northern and Western	16 8	50	(30-100)	47	(20-65)	-8	(-18; 2)	0.110 -8 4	(0-5)	5 (0-17)	0	(0-12)
	Southern	19 7	80	(40-150)	40	(15-80)	-30	(-42; -18)	<0.001* -50 2	(0-10)	8 (0-33)	3	(0-10)
	Central and Eastern	24 3	50	(25-100)	30	(15-70)	-10	(-14; -6)	<0.001* -33 2	(0-10)	10 (0-40)	0	(0-13)

services

  , survivors of COVID-19 with post acute -COVID-19[START_REF] Montani | Multidisciplinary approach for post-acute COVID-19 syndrome: time to break down the walls[END_REF], keens of the deceased from COVID-19[START_REF] Verdery I Sur | Tracking the reach of COVID-19 kin loss with a bereavement multiplier applied to the United States[END_REF], it is reasonable to assume an increased demand for efficient mental health services. The cooperation of different stakeholders is necessary to assure the accessible and un-interrupted mental health care services under the new circumstances and the implementation of new types and modalities services, including remote services, possibly post-COVID-19 services, liaison services within COVID-19 units etc. The European Psychiatric Association, as the European umbrella psychiatric association representing individual members and 44 national psychiatric associations should play a role in monitoring and reporting real world data from the represented countries and actively participate with other European stakeholders in shaping the recommendations and standards for the organisation of mental health care on the European level. However, given the high variation in the provision of psychiatric care across the countries observed in the survey, the EPA should facilitate the identification of country/ region -specific elements contributing to this variation and facilitate wider implementations of good clinical practice throughout Europe in the direction of the improvement of the mental health care accessibility and quality of mental health care acknowledging the local context.

Data availability statement

Conflict of interest

We declare no conflicts of interest.