Keywords:

However, the Voc has limited to about 0.6 V in the related P3HT-based BHJ devices with PCBM as the acceptor due to the high HOMO level (-5.2 eV) of P3HT, which consequently

General introduction

Energy is nowadays the most important and urgent problem facing humans, and the global demand for renewable energy is growing ever faster. Fossil fuels such as oil, gas, coal and other non-renewable energy are the main energy sources human consumed in the last century, their production and combustion have become a serious issue of our ecological environment, because of the large amount of carbon dioxide (CO2) emission, a key driver of global warming. The fossil fuels are not able to meet the future need due to their limited resources and sky-rocketing price, leading to ever urgent need for clean, renewable and sustainable energy sources. To achieve this goal is one of humanity's greatest challenges. The sun can provide our planet an inexhaustible and endless source of energy, and the Earth receives sufficient solar energy per hour to satisfy humans' annual demand. The energy irradiated on the Earth's surface from the sun each year is twice as the energy of all fossil and nuclear energy stores. Solar energy is therefore a promising alternative to these non-renewable energy sources and will play a significant role in meeting increasing energy demands.

The organic photovoltaic cells (OPV cells) promise to provide solar-to-electric energy conversion. It is one of the most important and promising long-term strategies for providing clean and renewable energy to our planet. It have attracted widespread attention as promising candidates to meet the increasing demand for renewable energy, due to their outstanding properties, such as ease of fabrication, mechanical flexibility, potential for renewable and green energy source low-cost potential, etc. [START_REF] Tang | Two-layer organic photovoltaic cell[END_REF][START_REF] Granström | Laminated fabrication of polymeric photovoltaic diodes[END_REF][START_REF] Brabec | Polymer-fullerene bulk-heterojunction solar cells[END_REF][START_REF] Peumans | Small molecular weight organic thin-film photodetectors and solar cells[END_REF][START_REF] Halls | Efficient photodiodes from interpenetrating polymer networks[END_REF] Currently, a record power conversion efficiency (PCE) of 13.2% for an OPV multi-junction cell was reached by Heliatek.(6) The development and synthesis of new organic semiconductors, that can be electron donor or acceptor for their use in the active layer is of great importance, together with technical progress in the device fabrication to reach OPV cells with high performance. Small molecules for OPVs have emerged as attractive candidates over their polymer counterparts, because of the well-defined but versatile chemical structures which allow easier energy level control, together with higher purity.

The work reported herein is focused on the development and synthesis of small molecules.

The motivation is to obtain new small molecules for use as active materials via green synthesis within as simple as possible procedures. In this work, we investigated few new materials from initial design to synthesis and to characterization.

The first chapter is a bibliographic review. We explain the functional principle, important characterizations, and different types of organic photovoltaic devices before focusing on the state-of-the-art electronic materials for OPV devices. A summary of the performance of various organic π-conjugated materials used as donors or acceptors for OPV cells is given.

The outlook on organic photovoltaics is summarized as the closing remark.

The second chapter focuses on theoretical calculations used for molecular design. In particular, a series of small molecules based on benzothiadiazole (Bz) core, 4,4'-di-n-octyldithieno [3,2-b:2',3'-d] silole (or dithienosilole, DTS) core, and subphthalocyanines (SubPcs) unit are theoretically investigated. Their electronic properties are predicted via theoretical calculations using density functional theory (DFT). The synthetic strategies for obtaining these molecules are also described.

The third chapter describes the experimental synthetic methods used for the molecules previously designed. In particular, direct arylation methods used as a green synthetic approach are presented, as well as traditional Suzuki cross-coupling. The E-Factor (kg waste / kg product) for assessing the environmental impact of the two manufacturing processes is also given.

In the fourth chapter, four obtained Bz-based small molecules are investigated in terms of optical, electrochemical, thermal properties and structural properties. We identify these molecules as promising materials for applications in OPV cells.

The fifth chapter presents the experimental procedures related to the synthesized molecules throughout this work.

Finally, the general conclusion and perspective of this work are presented.

Chapter I: Bibliography

Chapter I : Bibliography I Renewable solar energy Currently, more than 80% (as shown in the following two figures) of the worldwide energy supply is from carbon-based fossil fuels like oil, coal, gas, and other non-renewable sources.(7) Their production and combustion have become nowadays a major problem of our environment due to the emission of huge amount of carbon dioxide (CO2), a dominant greenhouse gas and a key driver of global climate change. Use of fossil fuels has led to serious ecological problems (global warming, pollution, planet degradation) and economic concerns (limited resources while sky-rocketing price). Therefore, renewable energies are one of the hot topics of the global energy strategy. The demand to explore and develop renewable energy sources has become increasingly urgent. Among the renewable energy resources: biomass, hydropower, geothermal, wind and solar, the inexhaustible solar energy appears as one of the most promising energies.(8) The sun represents the most powerful energy source available on earth. The energy received from sunlight striking the earth surface in 1 hour (120 000 TW, consisting of 5% ultraviolet, 43% visible and 52% infrared, as plotted in Figure I-3) is far more than all of the energy consumed on our planet in an entire year. [START_REF] Goldemberg | World energy assessment: overview: 2004 update[END_REF][START_REF] Armaroli | The future of energy supply: challenges and opportunities[END_REF] Consequently, the use of solar energy is one of the most significant challenges nowadays in scientific community. Organic photovoltaic cells (OPVs) which convert directly solar energy into electrical energy are considered as one of the most promising long-term and cost-effective solutions to meet the demand of clean and renewable energy source for our planet. OPVs therefore have attracted great concern in both science and industry. [START_REF] Brabec | Polymer-fullerene bulk-heterojunction solar cells[END_REF][START_REF] Cheng | Synthesis of Conjugated Polymers for Organic Solar Cell Applications[END_REF][START_REF] Günes | Conjugated Polymer-Based Organic Solar Cells[END_REF][START_REF] Chen | Development of Novel Conjugated Donor Polymers for High-Efficiency Bulk-Heterojunction Photovoltaic Devices[END_REF][START_REF] Li | Polyphenylene-Based Materials for Organic Photovoltaics[END_REF][START_REF] Chen | Recent Progress in Polymer Solar Cells: Manipulation of Polymer:Fullerene Morphology and the Formation of Efficient Inverted Polymer Solar Cells[END_REF][START_REF] Beaujuge | Molecular Design and Ordering Effects in π-Functional Materials for Transistor and Solar Cell Applications[END_REF][START_REF] Kan | A Series of Simple Oligomer-like Small Molecules Based on Oligothiophenes for Solution-Processed Solar Cells with High Efficiency[END_REF][START_REF] Kan | Small Molecules Based on Alkyl/Alkylthio-thieno[3,2-b]thiophene-Substituted Benzo[1,2-b:4,5-b′]dithiophene for Solution-Processed Solar Cells with High Performance[END_REF][START_REF] Zhao | Efficient organic solar cells processed from hydrocarbon solvents[END_REF][START_REF] Holliday | A rhodanine flanked nonfullerene acceptor for solution-processed organic photovoltaics[END_REF][START_REF] Zhou | Polymer Homo-Tandem Solar Cells with Best Efficiency of 11.3%[END_REF][START_REF] Sun | A molecular nematic liquid crystalline material for high-performance organic photovoltaics[END_REF][START_REF] Chen | An Efficient Triple-Junction Polymer Solar Cell Having a Power Conversion Efficiency Exceeding 11%[END_REF][START_REF] Heeger | Semiconducting polymers: the third generation[END_REF][START_REF] Heeger | 25th Anniversary Article: Bulk Heterojunction Solar Cells: Understanding the Mechanism of Operation[END_REF][START_REF] Park | Bulk heterojunction solar cells with internal quantum efficiency approaching 100%[END_REF][START_REF] Sun | Solution-processed small-molecule solar cells with 6.7% efficiency[END_REF][START_REF] Chen | High Performance Photovoltaic Applications Using Solution-Processed Small Molecules[END_REF][START_REF] Cnops | 8.4% efficient fullerene-free organic solar cells exploiting long-range exciton energy transfer[END_REF] The common building block of an organic photovoltaic system consists of one or several photoactive organic materials sandwiched between an anode and a cathode. A randomized network of active materials blending is often used as the organic photovoltaic system. It is named as a bulk heterojunction (BHJ). Figure I-4 depicts a BHJ-based organic photovoltaic device (OPV). The often used anode is indium tin oxide (ITO) coated on a glass substrate modified with an interfacial layer based on poly(ethylenedioxythiophene):poly(styrene sulfonic acid)(PEDOT:PSS) which offers good charge transport. The cathode is typically a low work function metal. The most frequently used cathode according to the literature is aluminum. Poly- (3-hexylthiophene) (P3HT) and [6,6]-phenyl-C61-butyric acid methyl ester (PCBM) blend is one of the most commonly used photoactive layer. [START_REF] Mazzio | The future of organic photovoltaics[END_REF] P3HT and PCBM are the most common electron donor and electron acceptor, respectively. The detailed photovoltaic process in organic photovoltaic cells will be given below (section II.2). There are mainly two kinds of organic materials for photovoltaic cells: polymers and small molecules. A common feature of both polymers and small molecules is that both of them are constituted of large -conjugated systems. OPV cells have drawn more and more attention from both academic and industrial researchers, as evidenced by the evaluation of the numbers of articles concerning organic solar cells and published in international journals over the last three decades (see .

Figure I-5: Number of publications dealing with organic solar cells during the period of 1980-2016 (Source Scopus).

As shown in Figure I-5, a big rise occurred in the very beginning of the last ten years, and the interest in organic solar cells is steadily continuing and increasing. Figure I-6 shows the best research-cell efficiencies for a variety of photovoltaic technologies, with leading efficiencies for inorganic multijunction cells up to 46%, and with efficiencies of single crystalline and multicrystalline Si cells surpassing 27% and 25%, respectively. Although these high efficiencies are appealing and promising, they are not the only standard for evaluating the potential of these technologies. The overwhelming drawbacks of these inorganic photovoltaic technologies are their high production costs owing to the amount of materials needed for these devices and vacuum processing demanded for production, as well their high fabrication costs. [START_REF] Mazzio | The future of organic photovoltaics[END_REF] Besides, inorganic silicon solar cells are expensive, rigid, heavy, and complicated to produce. Organic photovoltaic cells based on π-conjugated small molecules and polymers [START_REF] Green | Solar cell efficiency tables (version 47)[END_REF] are part of an emerging photovoltaic technology with best power conversion efficiencies (PCEs) for both triple-junction [START_REF] Chen | An Efficient Triple-Junction Polymer Solar Cell Having a Power Conversion Efficiency Exceeding 11%[END_REF] and single-junction achieving 11.5% [START_REF] Zhao | Efficient organic solar cells processed from hydrocarbon solvents[END_REF], with appealing properties such as low cost, light weight, flexibility, transparency, solution processability, printability, portability and large-area fabrication compatibility. [START_REF] Peumans | Small molecular weight organic thin-film photodetectors and solar cells[END_REF][START_REF] Günes | Conjugated Polymer-Based Organic Solar Cells[END_REF][START_REF] Kan | A Series of Simple Oligomer-like Small Molecules Based on Oligothiophenes for Solution-Processed Solar Cells with High Efficiency[END_REF][START_REF] Kan | Small Molecules Based on Alkyl/Alkylthio-thieno[3,2-b]thiophene-Substituted Benzo[1,2-b:4,5-b′]dithiophene for Solution-Processed Solar Cells with High Performance[END_REF][START_REF] Sun | A molecular nematic liquid crystalline material for high-performance organic photovoltaics[END_REF][START_REF] Heeger | Semiconducting polymers: the third generation[END_REF][START_REF] Heeger | 25th Anniversary Article: Bulk Heterojunction Solar Cells: Understanding the Mechanism of Operation[END_REF][START_REF] Park | Bulk heterojunction solar cells with internal quantum efficiency approaching 100%[END_REF][START_REF] Yu | Polymer photovoltiac cells: Enhanced efficiencies via a network of internal donor-acceptor heterojunctions[END_REF][START_REF] Li | High-efficiency solution processable polymer photovoltaic cells by selforganization of polymer blends[END_REF][START_REF] Thompson | Polymer-Fullerene Composite Solar Cells[END_REF][START_REF] Li | Polymer solar cells[END_REF][START_REF] Sariciftci | Photoinduced electron transfer from a conducting polymer to buckminsterfullerene[END_REF][START_REF] You | A polymer tandem solar cell with 10.6% power conversion efficiency[END_REF][START_REF] He | Enhanced power-conversion efficiency in polymer solar cells using an inverted device structure[END_REF][START_REF] Dou | Tandem polymer solar cells featuring a spectrally matched low-bandgap polymer[END_REF][START_REF] Kim | Rhodanine dye-based small molecule acceptors for organic photovoltaic cells[END_REF][START_REF] Krebs | Fabrication and processing of polymer solar cells: A review of printing and coating techniques[END_REF][START_REF] Zhang | A solution-processed high performance organic solar cell using a small molecule with the thieno [3, 2-b] thiophene central unit[END_REF][START_REF] Zhang | Small-molecule solar cells with efficiency over 9%[END_REF][START_REF] Kim | Efficient tandem polymer solar cells fabricated by all-solution processing[END_REF][START_REF] Peet | Efficiency enhancement in low-bandgap polymer solar cells by processing with alkane dithiols[END_REF][START_REF] Chen | Polymer solar cells with enhanced open-circuit voltage and efficiency[END_REF][START_REF] Guo | Polymer solar cells with enhanced fill factors[END_REF] The photovoltaic effect, namely, the transform of light into electricity, can be tracked to the pioneering studies of Becquerel in liquid electrolytes in 1839 [START_REF] Becquerel | Mémoire sur les effets électriques produits sous l'influence des rayons solaires[END_REF] and has been investigated for a wide range of materials. It took quite a long time before the first report by Chapin et al. in 1954 (52) on a silicon-based single p-n junction device with an efficiency of 6%. Almost 30 years after, Tang et al. [START_REF] Tang | Two-layer organic photovoltaic cell[END_REF] developed a two-layer organic photovoltaic cell and reported the first thin-film OPV cell affording a power conversion efficiency of about 1% in 1986. Hereafter, organic photovoltaics have become one of the state-of-the-art issues in science, as illustrated by the blooming and fruitful publication numbers shown in Figure I-5.

The OPV performances have been improved steadily to power conversion efficiencies over 11% (see . [START_REF] Zhao | Efficient organic solar cells processed from hydrocarbon solvents[END_REF][START_REF] Chen | An Efficient Triple-Junction Polymer Solar Cell Having a Power Conversion Efficiency Exceeding 11%[END_REF] In addition, the considerable contribution from world-wide industries such as Solarmer (USA), Heliatek (Germany) and so on, has so far leaded OPV to a new record power conversion efficiency of 13.2% set by Heliatek R&D teams (6) on 8 February, 2016.

Organic photovoltaic cells belong to a significant emerging technology in the modern era. It could facilitate the ever broader use of solar energy in coming years, wherever clean, renewable energy is needed, not only for industries such as building and construction materials, but also automotive, light architectural structures and flexible devices.

II. 2 Functional principle of organic photovoltaic cells

Contemporary organic photovoltaic cells are often based on a heterojunction made of two materials: an electron donor (D) and an electron acceptor (A). In the molecular case, the basic energy level diagram used to describe the operating principle of an OPV cell is shown in Figure I-7. The molecular energy levels involved in the light conversion into electricity are the highest occupied molecular orbital (HOMO) and the lowest unoccupied molecular orbital (LUMO), respectively. The ionization potential (IP) is the energy needed to remove an electron from a neutral molecule, and is related to the HOMO energy level. The fundamental gap, Efund or HOMO-LUMO energy gap is defined as the difference between IP and the electron affinity (EA). (53) The EA is the amount of energy released when an electron is added to a neutral molecule. EA is used to estimate the electron-withdrawing ability of a molecule to act as an electron-acceptor in an OPV device, and is thus linked to the LUMO energy level relative to vacuum. S0 indicates the (singlet) electronic ground state and S1 denotes the lowest (singlet) excited state (here considered to be available via one-photon absorption). The energy difference between S1 and S0 is called the optical gap (Eopt (eV)), given by the equation: [START_REF]Energy of Photon[END_REF]

E= hc / λ (1)

Where h is Planck's constant (6.626 × 10 -34 J•s) and c is the speed of light (2.998 × 10 8 m•s -1 ), and hc = 1240 eV• nm, thus

E (eV) = 1240 / λ (nm) (2)
Eopt is generally lower than the Efund, which is ascribed to the electrostatic bound between electron and hole in the excited state contrary to the ionized state. The exciton (or electronhole pair) binding energy EB is the difference between fundamental gap and the optical gap,

given by Figure I-7:

EB = Efund -Eopt (3)
In the material case, the molecular energy levels are broadened into electronic bands. The upper occupied band is referred to as the valence band and the lower unoccupied band is referred to as the conduction band. The material band gap is defined as the energy difference between the top of the valence band and the bottom of the conduction band.

As simply described in Figure I-8, the photovoltaic effect of converting sunlight into electricity in an organic photovoltaic cell can be summarized as the following four steps: [START_REF] Heeger | 25th Anniversary Article: Bulk Heterojunction Solar Cells: Understanding the Mechanism of Operation[END_REF][START_REF] Nunzi | Organic photovoltaic materials and devices[END_REF] (i) Photon absorption and excitons generation; (ii) excitons diffusion to the D/A interface;

(iii) excitons dissociation into free charge carriers (electrons and holes), and (iv) charge transport and charge collection at the electrodes, which produces current in the external circuit. The band gap, evaluated from the onset of the absorption band, are of 580 nm and 660 nm (i.e. 2.13 eV and 1.88 eV) for MDMO-PPV and P3HT, respectively.(37) A material presenting a band gap of 1.1 eV (1100 nm, Eopt (eV) = 1240/ λ (nm) ) is able to absorb 77% of the solar emission on the Earth surface, while the band gap of most of the semiconducting polymers is larger than 2 eV (620 nm) which restricts the possible harvest of solar photons to around 30%. [START_REF] Günes | Conjugated Polymer-Based Organic Solar Cells[END_REF][START_REF] Thompson | Polymer-Fullerene Composite Solar Cells[END_REF][START_REF] Nunzi | Organic photovoltaic materials and devices[END_REF] Thus, it is possible to harvest more sunlight and as a result, an increase in the photocurrent can be prospected by lowering the band gap of organic semiconductors. In addition, since the absorption coefficients of organic materials are as high as 10 5 cm -1 (see Figure I-9(up)), a thickness of active layer of only 100 nm is sufficient to absorb most of the incident photons. [START_REF] Nunzi | Organic photovoltaic materials and devices[END_REF] Increasing the layer thickness might hamper charge transport and therefore lower the fill factor (see , though it is often favorable to light absorption. Unlike what happens in inorganic semiconductors, and owing to the low dielectric constant of organic materials, the photon absorption at room temperature in organic materials results in coulombically bound neutral electron-hole pairs (excitons), rather than free charge carriers.

The exciton binding energy is in the range of 0.35 -0.5 eV. [START_REF] Scharber | Efficiency of bulk-heterojunction organic solar cells[END_REF] That is the reason why an electron donor/electron acceptor interface is needed in OPV devices to provide a driving force for the dissociations of excitons and the generation of free charge carriers.

II. 2-2 Diffusion and dissociation of excitons

For achievement of high power conversion in OPV, the maximum of excitons generated due to light absorption should give rise to the formation of free charge carriers (electron and hole).

It is shown that only 10% of the incident photons result in free charge carriers generation in conjugated polymers. [START_REF] Miranda | Ultrafast photogeneration of charged polarons in conjugated polymers[END_REF] One of the reasons for this low percentage is the low exciton lifetime (10 to 400 ps). [START_REF] Dimitrov | Singlet Exciton Lifetimes in Conjugated Polymer Films for Organic Solar Cells[END_REF] As a consequence, the order of magnitude of exciton diffusion length should be the same as the size of the photoactive domain, which limits the component thickness. [START_REF] Mozer | Conjugated polymer photovoltaic devices and materials[END_REF] Otherwise, excitons decay via luminescence or non-radiative recombination to the ground state, which is in competition with exciton diffusion before reaching the interface.

Generally, exciton diffusion lengths in organic semiconductors are of about 10-20 nm. [START_REF] Nunzi | Organic photovoltaic materials and devices[END_REF] Charge dissociation is one of the subsequent key steps for sunlight conversion into electricity.

In this step, the exciton is split in free charge carriers, the electron is transferred to the electron acceptor material and the hole to the electron donor material. Blending conjugated electron-donor polymers with electron-withdrawing materials such as the commonly used fullerene derivatives is a quite effective method for forming a charge transfer state (CTS). The CTS can be regarded as a state in which charge carriers are coulombically bound across the D/A interface. It is possible to promote charge dissociation from CTS when the energy offset (ΔE) between the LUMO of donor and the LUMO of acceptor is larger than the exciton binding energy. The minimum offset required for charge separation is approximately 0.3 eV. [START_REF] Scharber | Design rules for donors in bulk-heterojunction solar cells-Towards 10% energy-conversion efficiency[END_REF][START_REF] Brédas | Charge-Transfer and Energy-Transfer Processes in π-Conjugated Oligomers and Polymers: A Molecular Picture[END_REF][START_REF] Wang | Correlating molecular morphology with optoelectronic function in solar cells based on low band-gap copolymer: fullerene blends[END_REF] Then the photoinduced charges can migrate to their corresponding electrodes.

Therefore, the effect of charge recombination processes should be reduced or avoided as much as possible.

II. 2-3 Transport of charge carriers and charge collection

For efficient photovoltaic cells, the separated charges are required to be transported to the suitable electrodes within their lifetime which is estimated to be the order of magnitude of a few µs at 295 K. [START_REF] Vijila | Relation between charge carrier mobility and lifetime in organic photovoltaics[END_REF] The dominant driving force is the internal electric field created by the equalization of the Fermi energy levels of the two electrodes. Under the influence of the electric field, the charges remain separated (and thus no recombination after exciton dissociation) and migrate to the organic layers. [START_REF] Brédas | Charge-Transfer and Energy-Transfer Processes in π-Conjugated Oligomers and Polymers: A Molecular Picture[END_REF] Thus, the work functions of the electrodes (or of the charge transport layers) are determinant and require a careful choice of the electrode metals (and the interface layers). In addition, transport of charge carriers is strongly affected by charge recombination during the charge transport to the electrodes, especially if the transport medium for both holes and electrons is the same material.( 60) Therefore, charge carries recombination process should adequately slow down to let charge carriers reach the electrodes. Thus, the charge carrier mobilities (strongly dependent on the molecular organization of the material) through the active layer are determinant and require careful control on the active layer morphology. An important objective for OPV cells is to minimize the energy and charge loss processes for the purpose of improving the device efficiencies.

As the last step, charge carriers are collected from the device via two selective contacts (see . Usually, an indium tin oxide (ITO) due to its large optical transparency and high conductivity serves as the anode on one side, matching the HOMO levels of donor.( 65 The short-circuit current density, Jsc, corresponds to the maximum current delivered under lighting by a solar cell and is measured when no voltage is applied to the device. Jsc is mainly determined by factors associated with each of the four steps described above. A broad absorption spectrum is favorable to harvest as much as possible of the photons from the solar light and would increase the Jsc value. For a given absorption outline of a given material, the bottleneck of charge carriers is the charge mobility which is sensitive to the nanoscale morphology of the organic semiconducting-material thin film. [START_REF] Van Duren | Relating the Morphology of Poly(p-phenylene vinylene)/Methanofullerene Blends to Solar-Cell Performance[END_REF][START_REF] Hoppe | Efficiency limiting morphological factors of MDMO-PPV: PCBM plastic solar cells[END_REF][START_REF] Hoppe | Nanoscale Morphology of Conjugated Polymer/Fullerene-Based Bulk-Heterojunction Solar Cells[END_REF][START_REF] Gebeyehu | The interplay of efficiency and morphology in photovoltaic devices based on interpenetrating networks of conjugated polymers with fullerenes[END_REF][START_REF] Martens | Disclosure of the nanostructure of MDMO-PPV:PCBM bulk hetero-junction organic solar cells by a combination of SPM and TEM[END_REF]

(b) Open-circuit voltage (Voc)

The open circuit voltage, Voc, represents the maximum voltage obtainable from a solar cell, and is measured when the current equals to zero. Experimentally, the HOMO and LUMO energy levels can be evaluated from the oxidation potential of the donor and reduction potential of the acceptor via electrochemical characterization. In organic photovoltaic cells, it has been reported that the Voc value is not exactly determined by the energy difference between the HOMO of the donor material and the LUMO of the acceptor at the interface. [START_REF] Gadisa | Correlation between oxidation potential and open-circuit voltage of composite solar cells based on blends of polythiophenes/fullerene derivative[END_REF][START_REF] Mutolo | Enhanced Open-Circuit Voltage in Subphthalocyanine/C60 Organic Photovoltaic Cells[END_REF] Its value also depends on that of the binding energy of the excitons. Where e is the elementary charge, and the value of 0.3 V is an empirical factor. 0.3 V is found to be the deviations between the theoretical biggest built-in potential (VBI) and the Voc. [START_REF] Scharber | Design rules for donors in bulk-heterojunction solar cells-Towards 10% energy-conversion efficiency[END_REF] It is necessary that the electron acceptor material has a conduction band edge that is lower than that of the electron donor material. [START_REF] Hoppe | Organic solar cells: An overview[END_REF][START_REF] Mcgehee | Solar cells: pictures from the blended zone[END_REF][START_REF] Nelson | Organic photovoltaic films[END_REF][START_REF] Archer | Clean electricity from photovoltaics[END_REF] A minimum energy offset between the LUMO level of the polymer donor and the PCBM acceptor of approximately 0.3 eV has been demonstrated necessary to achieve efficient electron transfer from the LUMO of polymer donor to the LUMO of PCBM acceptor. [START_REF] Scharber | Design rules for donors in bulk-heterojunction solar cells-Towards 10% energy-conversion efficiency[END_REF][START_REF] Brédas | Charge-Transfer and Energy-Transfer Processes in π-Conjugated Oligomers and Polymers: A Molecular Picture[END_REF][START_REF] Koster | Bimolecular recombination in polymer/fullerene bulk heterojunction solar cells[END_REF] According to equation ( 4), to offer a high Voc, HOMO energy level of the donor can be decreased or LUMO energy level of the acceptor can be increased. However, such changes could simultaneously result in wider band gap and narrower absorption width, which means lower efficiency of photon absorption from the solar spectrum. Meanwhile, the LUMOs offset shown in Figure I-13 in BHJ should be larger than 0.3 eV.

In the Scharber model, the only inputs required are the HOMO and LUMO energy levels. The generated PCE values in the Scharber model should be understood as the potential performance that may be reached, if the assumptions can be met. These assumptions combine various additional conditions that have to be met to achieve a high-performance candidate, especially requirements associated with complicated optimization and control of BHJ activelayer morphology, interface behavior, and the dynamics of exciton and charge carriers. The standard parameters that reflect the assumptions in the Scharber model include a uniform external quantum efficiency of 65%, a fill factor (FF) of 0.65, a required LUMO offset of 0.3 eV between donor and acceptor for efficient charge separation, and an empirical loss parameter of 0.3 eV. However, there is no certainty that the top candidates will truly perform as well as expected, because their performances may be affected by various factors, such as morphology control, interface layer and device fabrication. It is indicated that the theoretical efficiency limit in the standard Scharber model is 11.1%, which requires energy levels of LUMO and HOMO of the ideal donor have to be -3.9 eV and -5.4 eV (Eg = 1.5 eV) respectively as the optimal parameter combination. 4).( 61) It is of great interest that the efficiency of the device keeps consistent with the LUMO offset (ΔE), precisely, the lower the offset, the higher the efficiency. Figure I-14 suggests that the photovoltaic efficiency of a BHJ solar cell should be more sensitive to variations of the LUMO offset compared to changes of the band gap of the donor. As a result, we can conclude that the choice of the D/A couple is as significant as the band gap of the donor material.

(c) Fill factor (FF)

The Fill factor (FF) is a parameter that is associated with Voc and Jsc, and evaluates the maximum portion of electric power that can be extracted from a photovoltaic cell. The FF can be given by the ratio of the electric power between the blue and purple areas the J-V curve (see Figure I-12), and defined by equation:

FF = Pmax / (Jsc x Voc) = (Jmax x Vmax) / (Jsc x Voc) ( 5
)
Where Jmax is the current density and the voltage at the maximum or ideal power point, and

Vmax is the voltage at the maximum or ideal power point. The FF provides a sign of how possibly charges can be extracted from a cell and is usually described as the "squareness" of the J-V curve, and will have a value of unity in an ideal case that corresponds to output power of Pideal. Alan J. Heeger [START_REF] Heeger | 25th Anniversary Article: Bulk Heterojunction Solar Cells: Understanding the Mechanism of Operation[END_REF] suggested that the FF in BHJ solar cells is affected by the competition between charge carriers sweep-out by the internal voltage (built in electric field)

and the loss of charge carriers by recombination. It is also indicated that the series and shunt resistances are two essential factors that affect the fill factor of a solar cell. [START_REF] Mazzio | The future of organic photovoltaics[END_REF][START_REF] Hoppe | Organic solar cells: An overview[END_REF][START_REF] Kippelen | Organic photovoltaics[END_REF] Besides, morphology is also of high influence on FF.( 81)

II. 3-3 Power conversion efficiency (PCE)

As mentioned previously, the performances of terrestrial solar cells are measured under AM1.5G conditions with incident power of 100 mW/cm 2 and at a temperature of 25°C. Power conversion efficiency (PCE) suggests the percentage of incident optical power that converts into electricity, and is defined as the ratio of output energy from a PV device to input energy from the solar spectrum. It is the most important and commonly used metric to determine the performance of a solar cell and compare it to the others. As sketched in the J-V curve, the maximum power point (Pmax) is localized on the J-V curve where the product of the current density and voltage is the highest.( 56) To determine the efficiency of a solar cell, the output power requires to be compared to the input power, as indicated below:

PCE = Pmax / Pin = (Jmax x Vmax) / Pin (6)
According to equation ( 6), the maximum power created in the external circuit is the product of the fill factor, open circuit voltage and short-circuit current density. Consequently, the power conversion efficiency can be described as:( 4)

PCE = (FF x Jsc x Voc) / Pin (7)
Where Pin represents the total power density of the incident light source. Therefore, the power conversion efficiency is mainly dependent on the three parameters: the open circuit voltage (Voc), the fill factor (FF), and the short-circuit current density (Jsc).

Furthermore, it is worth mentioning that external quantum efficiency (EQE) is a means for estimating the portion of current that can be generated by a special wavelength of light. It is defined as the number of charge carriers divided by the total number of incident photons. It

shows the potential that one absorbed photon will lead to the generation of one electron that can flow through an external field. EQE indicates the overall efficiency of the four principle steps in the photovoltaic process, as given by equation (8):

EQE(λ) = ηA (λ) x ηED (λ) x ηCT (λ) x ηCC (λ) (8)
Here, ηA is the photon absorption efficiency, the exciton diffusion efficiency ηED is the portion of photoinduced excitons that reaches the D/A interface prior to recombination. ηCT is the charge transfer efficiency, and the charge collection efficiency ηCC is the potential that a free charge carrier originated from excitons dissociation at the D/A interface reaches its respective electrodes, and λ is the wavelength of interest. [START_REF] Mazzio | The future of organic photovoltaics[END_REF][START_REF] Peumans | Efficient bulk heterojunction photovoltaic cells using small-molecular-weight organic thin films[END_REF] It shows the closer of the EQE value to 1, the more efficient of current generation at a certain wavelength, with limited recombination loss. Clearly, decreasing recombination loss will offer higher EQE values.

II. 4 Types of OPV and their architectures

D/A heterojunction devices can be divided into two principal types of architectures: bilayer (or planar) heterojunction ( 1) and bulk heterojunction (BHJ) that was first reported in 1995 [START_REF] Sun | Solution-processed small-molecule solar cells with 6.7% efficiency[END_REF][START_REF] Yu | Polymer photovoltiac cells: Enhanced efficiencies via a network of internal donor-acceptor heterojunctions[END_REF][START_REF] Brabec | Origin of the open circuit voltage of plastic solar cells[END_REF]. The first reported thin-film organic photovoltaic cells was a donor/acceptor (D/A) heterojunction cell, which gave a power conversion efficiency of approaching 1%. [START_REF] Tang | Two-layer organic photovoltaic cell[END_REF] This first report paved the way towards higher power conversion efficiencies reached thanks to the development of enhanced active materials. The performance of bilayer based organic photovoltaics is hampered by the short exciton diffusion length (5-20 nm) in organic materials, [START_REF] Nunzi | Organic photovoltaic materials and devices[END_REF][START_REF] Lunt | Exciton diffusion lengths of organic semiconductor thin films measured by spectrally resolved photoluminescence quenching[END_REF] because the optimal thickness of the photoactive layer in planar architecture is related to the exciton diffusion length. Therefore the optimal percentage of the incident light that the device can absorb and transform into electrical power is limited. The bilayer architecture is one of the most common types of OPV, but it causes efficiency loss not only due to excitons created too far away from the D/A interface, but also because of the low D/A interfacial area. One big advantage of bilayer heterojunction over single layer [START_REF] Hoppe | Organic solar cells: An overview[END_REF] is that holes and electrons can be effectively separated to reduce efficiency loss due to charge recombination after the excitons dissociation. But, it also constitutes a limit for high conversion efficiency, because the bilayer structures are primarily limited by the exciton diffusion length.( 32)

II. 4-2 Bulk heterojunction

Due to the limitation of bilayer heterojunction, further evolution was achieved in polymer devices by means of blends of the electron-rich and electron-deficient materials [START_REF] Granström | Laminated fabrication of polymeric photovoltaic diodes[END_REF][START_REF] Yu | Polymer photovoltiac cells: Enhanced efficiencies via a network of internal donor-acceptor heterojunctions[END_REF].

Different from bilayer heterojunction device, the active layer is blend of bicontinuous and interpenetrating donor and acceptor materials in a bulk heterojunction (BHJ) device. The BHJ concept was created by Yu et al.(35) and Halls et al.(5) in 1995, which is one of the state-ofthe-art device architectures for OPV so far. BHJ is resulted from phase separation in a 5-20 nm length scale of the donor and acceptor materials during spin-coating and solvent evaporation. It overcomes the exciton diffusion bottleneck [START_REF] Nunzi | Organic photovoltaic materials and devices[END_REF][START_REF] Lunt | Exciton diffusion lengths of organic semiconductor thin films measured by spectrally resolved photoluminescence quenching[END_REF] Bulk heterojunction can be fabricated via vacuum deposition or solution processing techniques. Soluble materials can be deposited from solution via spin coating. Some of small molecules can be deposited under vacuum via thermal evaporation, for instance, thin films of DCV5T-Me: C60 reported by Bäuerle et al. [START_REF] Fitzner | Correlation of π-Conjugated Oligomer Structure with Film Morphology and Organic Solar Cell Performance[END_REF] was vacuum deposited in BHJ single layer.

Active layers of metal phthalocyanine: C60 and DCV6T: C60 were vacuum processed in a tandem cell. Because vacuum deposition allows for good control of the layer thickness which is necessary for the optimization of the device stack with regard to optical interference effects. [START_REF] Riede | Efficient Organic Tandem Solar Cells based on Small Molecules[END_REF] Vacuum deposition for OPV devices in an efficient roll-to-roll-process developed by Heliatek is an innovative technology that meets pioneer spirit. (6) In addition, thermal annealing, as another method for the fabrication of bulk heterojunction device completed with a metal cathode, was used to improve the efficiency of polymer solar cells. [START_REF] Padinger | Effects of Postproduction Treatment on Plastic Solar Cells[END_REF] This effect was ascribed to polymer chain alignment, leading to an increase in the formation of an interfacial layer at the organic/cathode interface or the charge carrier mobility. Another effect of efficiency enhancement in BHJ cells was attributed to a confined geometry by using a metal contact during annealing, preventing the formation of a rough surface morphology while allowing for the formation of an interpenetrating donor-acceptor network.( 82) Whereas solution-processed BHJ type architecture with a fullerene acceptor was first reported in 1995 by Yu et al.(35) and Halls et al.(5). Over the last decade, the solution-processed BHJ OPVs has shown dramatic improvement in power conversion efficiency from less than 1% in the earliest publications to 11.7% [START_REF] Zhao | Efficient organic solar cells processed from hydrocarbon solvents[END_REF] in the very recent literature. The power conversion efficiency of OPV cells based on small molecules and polymers have improved steadily over the past decade. Moreover, bulk-heterojunction OPVs based on small molecules (SM-BHJ)

have become a competitive alternative to the more widely investigated counterparts based on conjugated polymers.( 92) So far, the performance of both polymer-based BHJ [START_REF] Zhou | Polymer Homo-Tandem Solar Cells with Best Efficiency of 11.3%[END_REF][START_REF] Chen | An Efficient Triple-Junction Polymer Solar Cell Having a Power Conversion Efficiency Exceeding 11%[END_REF][START_REF] You | A polymer tandem solar cell with 10.6% power conversion efficiency[END_REF][START_REF] Chen | Single-Junction Polymer Solar Cells Exceeding 10% Power Conversion Efficiency[END_REF][START_REF] Liu | Aggregation and morphology control enables multiple cases of high-efficiency polymer solar cells[END_REF][START_REF] Kang | Simplified Tandem Polymer Solar Cells with an Ideal Self-Organized Recombination Layer[END_REF][START_REF] He | Single-junction polymer solar cells with high efficiency and photovoltage[END_REF][START_REF] Zhang | Realizing over 10% efficiency in polymer solar cell by device optimization[END_REF][START_REF] Liu | Single-Junction Polymer Solar Cells with Over 10% Efficiency by a Novel Two-Dimensional Donor-Acceptor Conjugated Copolymer[END_REF][START_REF] Liu | Enhanced efficiency of polymer solar cells by adding a high-mobility conjugated polymer[END_REF](100) and SM-BHJ [START_REF] Kan | A Series of Simple Oligomer-like Small Molecules Based on Oligothiophenes for Solution-Processed Solar Cells with High Efficiency[END_REF][START_REF] Liu | Solution-processed small-molecule solar cells: breaking the 10% power conversion efficiency[END_REF] are comparable, with power conversion efficiency over 10%.

BHJ is regarded as the state of the art active layer morphology so far, because the interfacial area between donor and acceptor phases in a bulk heterojunction is greatly improved.

Therefore, compared to bilayer heterojunction, the bicontinuous, nanoscale and interpenetrating network formed in BHJ architecture leads to higher performance of the OPV devices. [START_REF] Hoppe | Organic solar cells: An overview[END_REF][START_REF] Lin | Small molecule semiconductors for high-efficiency organic photovoltaics[END_REF]101) The progress is mainly ascribed to the improvement of the D/A heterojunction [START_REF] Tang | Two-layer organic photovoltaic cell[END_REF]102) that acts as a dissociation position for the coulombically bound photon generated excitons. However, due to the complicated nanomorphology, a D/A blend is hard to control and optimize the active layer morphology.( 68)

II. 4-3 Tandem OPV cells

A class of OPV technology is "tandem cell" architecture (as shown in Figure I-17(left)), [START_REF] Kim | Efficient tandem polymer solar cells fabricated by all-solution processing[END_REF] which is based on a multilayer structure that comprises two or even more independent active layers in series. It reveals numerous advantages for further improvement, as reviewed by Christoph J. Brabec et al. in 2009(79) and by Yang Yang et al. in 2013(103). It is sufficient to realize the practical application of plastic photovoltaics in rooftop solar panel. A wide band-gap material for the first cell and a relatively lower band-gap semiconductor for the second charge-separation layer with are typically used in the tandem cells. [START_REF] Mazzio | The future of organic photovoltaics[END_REF][START_REF] Kim | Efficient tandem polymer solar cells fabricated by all-solution processing[END_REF]104) The tandem architecture allows to address two particular weakness originated from the inherent properties of π-conjugated organic materials.(105-109) To begin with, the combination of two semiconductors with different band gaps enables a wide absorption over a wide range of solar emission spectrum due to the complementary absorption spectra from each layer (see Figure I-17(right)). The power conversion efficiency of the tandem cell is inherently higher than that of a single cell made from the narrower band-gap material, resulting from the higher energy of electron-hole pair generated by photons compared to that of the energy gap that rapidly relax to the band edges respectively. Moreover, owing to the low mobility of the charge carriers, an addition in the thickness of the active layer enhances the internal resistance of the device, as a consequence, both the Voc and fill factor (FF) are improved.(110) Hence, the tandem cells are able to give a higher optical density over a broader fraction of the solar spectrum. In other words, the tandem cell structure is beneficial to the efficiency of light harvest. The organic tandem photovoltaic cells have showed the highest performance of a bulk heterojunction solar cell to date, achieving over 11%. [START_REF] Zhou | Polymer Homo-Tandem Solar Cells with Best Efficiency of 11.3%[END_REF][START_REF] Chen | An Efficient Triple-Junction Polymer Solar Cell Having a Power Conversion Efficiency Exceeding 11%[END_REF]111) Specifically, a new record power conversion efficiency of 13.2% for a multi-junction device had been set by Heliatek on February 8, 2016.(6) However, one major issue with tandem cells is that the total current of the cell is limited by the current generated in the front or back cell which is lowest. Therefore, to make full use of a tandem cell, the current generated in each sub-cell should match each other. Determining by the specific absorption and charge carrier mobilities of semiconducting materials, tandem cells generally use thicker back cell than the front cell so that the photocurrent created in each sub-cell are balanced. [START_REF] Kim | Efficient tandem polymer solar cells fabricated by all-solution processing[END_REF]112) Due to the number of sub-cells and required precision of various processing steps, the scale up to roll-to-roll production in tandem cells is even a greater challenge.

II. 5 Organic semiconducting materials for OPVs

Generally, organic semiconductors have a wide band gap above 1.4 eV but less than 3 eV, materials with a band gap above 3 eV are considered as insulators. Organic semiconductors have been the focus of considerable research due to their intrinsic properties. [START_REF] Cheng | Synthesis of Conjugated Polymers for Organic Solar Cell Applications[END_REF]113) The explored applications of organic semiconductors include organic light emitting diodes (OLED)(114-116), organic field effect transistors (OFET)(117-119), and organic photovoltaics (OPV) [START_REF] Cheng | Synthesis of Conjugated Polymers for Organic Solar Cell Applications[END_REF][START_REF] Günes | Conjugated Polymer-Based Organic Solar Cells[END_REF][START_REF] Li | High-efficiency solution processable polymer photovoltaic cells by selforganization of polymer blends[END_REF][START_REF] You | A polymer tandem solar cell with 10.6% power conversion efficiency[END_REF][START_REF] Mozer | Conjugated polymer photovoltaic devices and materials[END_REF].

II. 5-1 Introduction of semi-conductor property and π-conjugation

The molecular structure of organic semiconductors consistently contains a π-conjugated backbone, along which the carbon or hetero atoms (nitrogen, oxygen and sulfur) are sp 2 pz-hybridized. The first classic example of a semiconducting polymer is polyacetylene (containing alternating single and double bonds, the structure and π orbital are showed in For organic semiconductors, the charge carrier mobilities strongly rely on the morphology, for instance, the charge carrier mobilities of highly disordered amorphous films (normally 10 -6 to 10 -3 cm 2 V -1 S -1 ) can be enhanced over several orders of magnitude when making them highly ordered crystalline (over 1 cm 2 V -1 S -1 ).( 123) Currently, organic photovoltaic donors are principally based on two types of electrondonating materials: polymers [START_REF] Günes | Conjugated Polymer-Based Organic Solar Cells[END_REF][START_REF] Heeger | Semiconducting polymers: the third generation[END_REF][START_REF] Sun | Solution-processed small-molecule solar cells with 6.7% efficiency[END_REF](126)(127)(128) and small molecules [START_REF] Kan | A Series of Simple Oligomer-like Small Molecules Based on Oligothiophenes for Solution-Processed Solar Cells with High Efficiency[END_REF][START_REF] Kan | Small Molecules Based on Alkyl/Alkylthio-thieno[3,2-b]thiophene-Substituted Benzo[1,2-b:4,5-b′]dithiophene for Solution-Processed Solar Cells with High Performance[END_REF][START_REF] Chen | High Performance Photovoltaic Applications Using Solution-Processed Small Molecules[END_REF][START_REF] Zhang | A solution-processed high performance organic solar cell using a small molecule with the thieno [3, 2-b] thiophene central unit[END_REF][START_REF] Zhang | Small-molecule solar cells with efficiency over 9%[END_REF][START_REF] Lin | Small molecule semiconductors for high-efficiency organic photovoltaics[END_REF][START_REF] Liu | Solution-processed small-molecule solar cells: breaking the 10% power conversion efficiency[END_REF][START_REF] Walker | Small Molecule Solution-Processed Bulk Heterojunction Solar Cells[END_REF](129)(130)(131)(132)(133), and OPV acceptors are mainly based on either fullerene or their derivatives [START_REF] Brabec | Polymer-fullerene bulk-heterojunction solar cells[END_REF][START_REF] Sun | Solution-processed small-molecule solar cells with 6.7% efficiency[END_REF][START_REF] Yu | Polymer photovoltiac cells: Enhanced efficiencies via a network of internal donor-acceptor heterojunctions[END_REF][START_REF] Zhang | A solution-processed high performance organic solar cell using a small molecule with the thieno [3, 2-b] thiophene central unit[END_REF]127,131) and fullerene-free materials including both polymer and small molecules) [START_REF] Holliday | A rhodanine flanked nonfullerene acceptor for solution-processed organic photovoltaics[END_REF][START_REF] Cnops | 8.4% efficient fullerene-free organic solar cells exploiting long-range exciton energy transfer[END_REF]128,(134)(135)(136). (PSBTBT), poly [2,6-(4,4-bis(2-ethylhexyl)-4H-cyclopenta [2,1-b;3,4-b′]dithiophene)-alt-4,7- (PffBT4T-2OD). The power conversion efficiencies of BHJ architecture fabricated by blends of conjugated polymers and soluble fullerene derivatives have seen a dramatic rise from around 1% in 1992 [START_REF] Sariciftci | Photoinduced electron transfer from a conducting polymer to buckminsterfullerene[END_REF] to over 10% in 2013 -2015(23, 25, 40, 93-99), as evidenced by the performance shown in Table I [START_REF] Chen | An Efficient Triple-Junction Polymer Solar Cell Having a Power Conversion Efficiency Exceeding 11%[END_REF], and a new record of 13.2% set by Heliatek for multijunction (6).

(b) Small-molecules based donors

As succinctly illustrated in Figure I-24, solution-processed π-conjugated small molecules with narrow band gap have recently gained more attention for use as the donor component in BHJ solar cells with fullerene derivatives as electron acceptor materials. In regard to the performance in BHJ-OPVs, small molecules have almost caught up with their polymer counterparts. (19-21, 24, 29, 45, 84, 129, 130, 132, 137, 150) Small molecules-based OPV cells (SM-OPVs) are an attractive and comparable alternative to polymer-based OPV cells. Small molecules offer several advantages compared to their polymer counterparts, including well-defined but versatile chemical structures which allow easier energy level control, higher material purity, better ordered, generally higher Voc [START_REF] Walker | Small Molecule Solution-Processed Bulk Heterojunction Solar Cells[END_REF], reduced even no batch-to-batch variation, and good solubility via employment of the appropriate type, number and length of side chains. [START_REF] Sun | Solution-processed small-molecule solar cells with 6.7% efficiency[END_REF]130,133,(151)(152)(153) Furthermore, small molecule processed through solution deposition affords the possibility of cost-effective roll-to-roll (R2R) manufacture. Similarly, small molecules are also based on electron donor and electron acceptor cores. 2-yl)thiophen-2-yl)- [START_REF] Tang | Two-layer organic photovoltaic cell[END_REF][START_REF] Granström | Laminated fabrication of polymeric photovoltaic diodes[END_REF][START_REF] Halls | Efficient photodiodes from interpenetrating polymer networks[END_REF]thiadiazolo [3,4-c]pyridine)-3,3'-di-2-ethylhexylsilylene-2,2'bithiophene (DTS(PTTh2)2), the design of which is based on a core acceptor/donor/acceptor (A/D/A) framework incorporated with donor end-capping units. The electron-rich core dithienosilole (DTS) unit linked with two electron-deficient units [START_REF] Tang | Two-layer organic photovoltaic cell[END_REF][START_REF] Granström | Laminated fabrication of polymeric photovoltaic diodes[END_REF][START_REF] Halls | Efficient photodiodes from interpenetrating polymer networks[END_REF]thiadiazole [3,4,c]pyridine (PT) leads to strong intramolecular charge transfer feature, and the 4-coordinate silicon atom allows for incorporation of alkyl chains to enable good solubility in organic solvent.( 29) DTS(PTTh2)2 and p-DTS(FBTTh2)2 have been well investigated by Alan J. Small molecules are good candidates for OPVs not only due to their advantages but also their high performances. [START_REF] Kan | A Series of Simple Oligomer-like Small Molecules Based on Oligothiophenes for Solution-Processed Solar Cells with High Efficiency[END_REF]129) So far, the performance of small molecules-based BHJ device [START_REF] Kan | A Series of Simple Oligomer-like Small Molecules Based on Oligothiophenes for Solution-Processed Solar Cells with High Efficiency[END_REF][START_REF] Liu | Solution-processed small-molecule solar cells: breaking the 10% power conversion efficiency[END_REF] is comparable to that of polymer-based OPV devices [START_REF] Zhou | Polymer Homo-Tandem Solar Cells with Best Efficiency of 11.3%[END_REF][START_REF] Chen | An Efficient Triple-Junction Polymer Solar Cell Having a Power Conversion Efficiency Exceeding 11%[END_REF][START_REF] You | A polymer tandem solar cell with 10.6% power conversion efficiency[END_REF][START_REF] Chen | Single-Junction Polymer Solar Cells Exceeding 10% Power Conversion Efficiency[END_REF][START_REF] Liu | Aggregation and morphology control enables multiple cases of high-efficiency polymer solar cells[END_REF][START_REF] Kang | Simplified Tandem Polymer Solar Cells with an Ideal Self-Organized Recombination Layer[END_REF][START_REF] He | Single-junction polymer solar cells with high efficiency and photovoltage[END_REF][START_REF] Zhang | Realizing over 10% efficiency in polymer solar cell by device optimization[END_REF][START_REF] Liu | Single-Junction Polymer Solar Cells with Over 10% Efficiency by a Novel Two-Dimensional Donor-Acceptor Conjugated Copolymer[END_REF][START_REF] Liu | Enhanced efficiency of polymer solar cells by adding a high-mobility conjugated polymer[END_REF](100) (d) Non-fullerene acceptors While fullerene derivatives are the most commonly representative electron acceptors used in OPVs, they also have a few distinct disadvantages, such as weak absorption in the visible region, difficulty in modifying the energy levels, high cost of synthesis and purification.(159-162) Therefore, the design and synthesis of fullerene-free (n-type) materials including polymers and small molecules have recently drawn more and more attention. [START_REF] Holliday | A rhodanine flanked nonfullerene acceptor for solution-processed organic photovoltaics[END_REF][START_REF] Kim | Rhodanine dye-based small molecule acceptors for organic photovoltaic cells[END_REF][START_REF] Lin | Small molecule semiconductors for high-efficiency organic photovoltaics[END_REF]130,(134)(135)(136)163) Different from fullerene derivatives, the energy levels of polymer and small molecular acceptors can be tuned more efficiently by chemistry engineering. It is worth noting that more and more research efforts are devoted to non-fullerene acceptors, although the efficiency of devices based on these materials are lower than that of fullerene systems. Efficiency reaching 6.8% has been achieved for the device based on polymer and small molecular blend by Y. Lin et al. in 2015.(164) A new record efficiency of 9.6% has been reached for OPV device based on fullerene-free acceptors by Y. Lin et al. in 2016.(165) Therefore, developing fullerene-free acceptors would be a promising approach for costeffective and high performance devices.

II. 6 Outlook

Many novel and excellent polymers and small molecules have been designed and synthesized for organic photovoltaics, and an attractive efficiency of over 10% PCE has been achieved.

Concerning chemical design, the D/A (also named push-pull) framework has confirmed to be a smart strategy to obtain good light absorption. Apart from the absorption, energy levels, morphologies, solubility and mobility etc. could also be well controlled via careful efforts in molecule design. Various electron donor cores, electron acceptor units, terminal units, as well as bridges with different conjugation lengths have been employed in the initial design.

Attributed to the complicated and multi-step photoelectric conversion processes, it is necessary and important to obtain a delicate balance among molecular design, (30, 81, 84, 129, 130, 137, 153, 170, 171) morphology,(172, 173) interfacial layer,(174-176) and device fabrication [START_REF] Chen | Recent Progress in Polymer Solar Cells: Manipulation of Polymer:Fullerene Morphology and the Formation of Efficient Inverted Polymer Solar Cells[END_REF][START_REF] Kyaw | Efficient Solution-Processed Small-Molecule Solar Cells with Inverted Structure[END_REF]178) to optimize the efficiencies of OPV devices (179).

For these prospects, the following issues need to be paid attention and solved:

( Besides, morphology could be controlled and optimized by different process methods, such as vacuum deposition and thermal annealing. In the phase separation of active layer, the sweepout time is confined to the charge mobility and thus by the blend morphology of the phase separation in BHJ materials. Therefore, improvement in the morphology with better structural order could obviously enhance the mobility and thus result in a reduction of the sweep-out time, which could facilitate the charge carriers to sweep out to the external circuit prior to their recombination to ground state, giving rise to higher FF.( 27) However, to finely control the phase separation of different D/A blend films and thus to optimize and achieve ideal morphology which can lead to the highest theoretical efficiency is still a big challenge.

(3) Green chemistry for material synthesis. Organic materials for OPV have been studied

intensively in recent years. However, as the technologies become commercialized, these materials will be required in large scale. Thus, efficient syntheses of these materials are of great significance. We should also bear in mind that tandem-architecture technology is advantageous for efficient and complementary absorption. It has been demonstrated experimentally that realizing tandem structure can be highly favorable to improve the performance of devices based on materials

unable to fully realize their potential. [START_REF] Ameri | Organic tandem solar cells: A review[END_REF] Besides, the lifetime of organic solar cells is still an important challenge to realize commercialization.

To conclude, organic photovoltaics have gone through enormous progress in the last decade.

The device performance was greatly improved from below 3% to the present 13.2% power conversion efficiency. If OPVs holds its promise, we believe that it can soon become a widespread, clean and renewable energy source to meet the increasing energy demand in our planet and to benefit future generations.

III PhD objectives

As a clean and sustainable energy source, organic photovoltaic cells seem to have the potential of replacing the often used fossil fuels and satisfying the increasingly energy demand in our planet. The striking progress in organic photovoltaics encourages chemists to design and synthesis new conjugated materials for OPVs, which also have drawn our attention. Therefore, to design and synthesize novel organic small molecules for application in OPV devices is the aim of our team, attributed to the advantages of small molecules (see section II. 5-4(b)). According to numerous experimental and theoretical reports about molecules design, the push-pull structures offer a facile way to tune the physical and optoelectronic properties of electron-donating or electron-accepting materials in organic photovoltaic cells. were chosen as building blocks for the backbone of π-conjugated small molecules. [START_REF] Zhou | Rational Design of High Performance Conjugated Polymers for Organic Solar Cells[END_REF]137) Attributed to the feature of fluorine (will be discussed in detail in chapter II), fluorinated benzothiadiazole (ffBz) were also chosen as an acceptor building block. To ensure sufficient solubility of small molecules, alkyl (linear octyl-and branched 2-ethylhexyl-) cyanoacetate were selected as the terminal group. Linear side groups may lead to a relatively coplanar backbone structure thus allows for closer π-π stacking distance and consequently increased charge mobility, whereas branched side chains may result in steric hindrance if molecular chains undergo packing. [START_REF] Wang | Correlating molecular morphology with optoelectronic function in solar cells based on low band-gap copolymer: fullerene blends[END_REF] Therefore, the difference in the nature of the alkyl chains would provide us interesting results leading to different morphologies in a blend. [START_REF] Zhou | Rational Design of High Performance Conjugated Polymers for Organic Solar Cells[END_REF] Once a molecule was designed, the following aim was to synthesize them within as less as possible steps. The synthesis of these materials originated from appropriate precursors was conducted with co-workers via different methods in parallel. Interestingly, our designed Bzbased small molecules were able to be obtained in a considerable yield through eco-friendly synthetic approach (direct arylation) within only two steps. With regard to synthesized molecules, material characterizations were performed in terms of electrochemistry, UV-Vis absorption, fluorescence, thermal characteristics. Atomic Force Microscopy (AFM) was also envisaged to study the morphology of thin films. As the final target, the synthesized materials should be subjected to the measurement in OPV device via collaboration with Laboratoire d'analyse et d'architecture des systèmes (LAAS-CNRS) and the Centro de Investigaciones en Óptica (CIO-León) in Mexico.

To be mentioned, subphthalocyanines (SubPcs)-based small molecules were also envisaged as an extension of molecular design, due to their unique optical and electronic properties and thus great potential in the field of photonic devices. (185,186) Herein, in brief, the following three aspects are the primary objectives of this PhD thesis and will be further discussed in the following successive chapters.

( The computations conducted in the CEP provide insights into novel and promising molecular patterns that can be further studied by more detailed simulations, which facilitate the reasonable design of new materials. However, it should be pointed out that most of promising candidates would be difficult to synthesize due to their structural complexity (see Figure , notwithstanding these massive design choices. Actually, these predicted molecules probably won't be soluble and adding alkyl chain is a supplementary difficulty. thiadiazole, diBrBz) is among the best fragments that lead to the highest efficiencies and proved to be stable, which could be a guiding for us to design molecules built from diBrBz.

) 1

I. 2 Theoretical work on active-layer interface

In addition to the high-throughput design effort to organic photovoltaics from the Harvard Clean Energy Project, other advanced theoretical investigations on the complicated bilayer interfacial interaction were reported. The aim is to provide visual view to help researchers Therefore, designing new candidates for organic solar cells with the modern advanced computational technology has been a widely recognized approach, and these theoretical simulations provide us useful tools for the optimization of molecular design and for the understanding of interface morphology.

II Small molecules design

From the previous description, we need to bear in mind that the design of new materials for organic photovoltaics involves not only careful balances between Jsc, Voc and FF, but also a comprehensive understanding of all of the optical and electronic processes that occur in a solid-state OPV. Many efforts have been recently devoted to the design and synthesis of lowband gap copolymers combining alternating donor and acceptor (D-A) fragments, used as electron-donating components to harvest the low-energy photon portion of the solar spectrum, in the other words, to achieve wide spectrum in the Infrared and near-Infrared region.(199-

201)

Power conversion efficiencies beyond 10% have been achieved in organic BHJ devices using D-A units.( 40) However, due to the disadvantages of polymer synthesis and purification, increasingly attention nowadays has turned to small molecules. Thus, we aimed to develop a new series of organic small molecules for photovoltaic applications. To achieve our objectives, the design of such materials needs to be first conducted. It is most of time accomplished by an exhaustive bibliographic work that is evidenced by the II.5-4 part of Chapter I. Moreover, we have used theoretical calculations to anticipate the energy levels of the frontier orbitals (HOMO and LUMO) of target molecules. In the search for new and efficient materials for organic photovoltaics, many small molecules have been designed and synthesized in the past few years.( 84) Nowadays, their efficiency in term of photo conversion (DRCN5T: 10.08%) [START_REF] Kan | A Series of Simple Oligomer-like Small Molecules Based on Oligothiophenes for Solution-Processed Solar Cells with High Efficiency[END_REF] has become equivalent to that of polymers (PffBT4T-2OD: 10.8%) [START_REF] Liu | Aggregation and morphology control enables multiple cases of high-efficiency polymer solar cells[END_REF]202) for single junction BHJ devices. Besides, their synthetic reproducibility and the numerous attainable structures make them very attractive for generating materials with easy energy level control, mobility, solid packing mode and solubility. [START_REF] Lin | Small molecule semiconductors for high-efficiency organic photovoltaics[END_REF]153) To our knowledge, alternating electron-rich and electron-deficient (D-A)

fragments in a conjugated polymer backbone is one of the most commonly employed approaches for tuning the material band gap. In the same manner, this strategy has also been proven to be a good strategy for reaching efficient narrow band-gap small molecules. Various central electron acceptor cores like Bz, DPP, etc. and electron donor cores such as DTS, BDT, FL and so on, (see Figure I-22), terminal units (dicyanovinyl, alkyl cyanoacetate, rhodanine, and 1,3-indanedione), as well as π-conjugated bridges made of thiophene rings with different conjugation lengths have been used for the design of small functional molecules. [START_REF] Zhou | Rational Design of High Performance Conjugated Polymers for Organic Solar Cells[END_REF]137) Here we will focus on symmetrical structures for simplicity, using the D-A strategy. In consequence, an A or D fragment will be in the center of the molecule. In our work, a series of small molecules comprised of the building block Bz and those of DTS as the central core were designed.

II. 1 Small molecules based on benzothiadiazole (Bz) core

Since Bz has been explored as a common acceptor unit in many high performance materials [START_REF] Chen | Development of Novel Conjugated Donor Polymers for High-Efficiency Bulk-Heterojunction Photovoltaic Devices[END_REF][START_REF] Park | Bulk heterojunction solar cells with internal quantum efficiency approaching 100%[END_REF][START_REF] Peet | Efficiency enhancement in low-bandgap polymer solar cells by processing with alkane dithiols[END_REF]127,203,204), which is also in good agreement with the five most enriched moieties of the Harvard Clean Energy Project, it was chosen in our molecular design. Adequate lengths of alkyl chains can ensure the material solubility. Octyl (linear chain) cyanoacetate and 2-ethylhexyl (branched chain) cyanoacetate as the terminal groups were proved to confer a good solubility of small molecules and thus promote self-organization in nanoaggregate structures which contribute to enhanced photovoltaic performances.( 205)

Besides, linear side groups may lead to a relatively coplanar backbone structure thus allows for closer π-π stacking distance and consequently increased charge mobility, whereas branched side chains may result in steric hindrance prohibiting molecular packing.( 63)

Therefore, the difference in the nature of the alkyl chains would provide us interesting results leading to different morphologies in blend.( 81) Thus, the combination of the Bz, thiophene or bithiophene and alkyl (octyl-and 2-ethylhexyl) cyanoacetate fragments leads to one kind of non-sophisticated designed molecules: A-D-A-D-A-type symmetric molecules (as provided in

Figure . The differences between these molecules are the number of thiophene rings forming the π-conjugation bridges and the nature of the alkyl chains. As illustrated in Scheme II-1, to obtain the target molecules, the first step consists of coupling 4,7-dibromobenzo-2,1,3-thiadiazole with thienyl carboxaldehyde via a chosen coupling method, leading to a D-A-D intermediate. In that purpose, synthesis methods via eco-friendly synthetic approaches are of paramount importance. Thus, we intend to investigate this first coupling by comparing the classical Suzuki or Stille coupling with direct arylation, which could be a method of choice for the present work. The chosen synthetic approach will be further discussed in the next chapter.

Bz(T 1 CAEH) 2 Bz(T 1 CAO) 2 Bz(T 2 CAO) 2 Bz(T 2 CAEH) 2 Bz(T 3 CAEH) 2 Bz(T 4 CAEH) 2 Bz(T 4 CAO) 2 Bz(T 3 CAO) 2
Scheme II-1: Synthesis strategies designed for obtaining Bz-based small molecules (R= octyl cyanoacete and 2-ethylhexyl cyanoacetate).

Then, the D-A-D intermediate backbone will be further elongated by double Knoevenagel condensation, leading finally in only two steps to an A-D-A-D-A structure, with the benzothiadiazole as the central core.

II. 2 Small molecules based on dithienosilole (DTS) core

The withdrawing block (2,1,3-benzothiadiazole, Bz) have been used as electron donors for smallmolecule based OPV. By changing cyano group to dicyanovinylene group, the efficiency decreased from 2.3% to 0.07%, which suggests that the cyano is better than dicyanovinylene group in this case (see Table II-1).( 210) But these molecules with such terminal groups are not very soluble, thus their applications in OPV device are limited. Another two A-D-D-D-A structure small molecules, DCAO3TSi and C8-Ester, with the DTS unit as the central building block, terthiophene as the π-bridge and octyl cyanoacetate as the terminal acceptor group, also showed moderate performance, offering efficiencies of 4.35% and 5.84%, respectively.(205, 211) Here the alkyl cyanoacetate group is a good compromise between dicyanovinyl for electron withdrawing and terminal alkyl chains for the solubility. For molecules DTS(PTTh2)2 and p-DTS(FBTTh2)2, the two electron acceptor units ( [START_REF] Tang | Two-layer organic photovoltaic cell[END_REF][START_REF] Granström | Laminated fabrication of polymeric photovoltaic diodes[END_REF][START_REF] Halls | Efficient photodiodes from interpenetrating polymer networks[END_REF] thiadiazolo [3,4-c] II-1). Among all the small molecules listed in Table II- for DTS(TBzT1CAO)2, the third step will be the coupling between fragments diTDTS and BrBzT2CHO, and the last step will be double Knoevenagel condensation.

4,4'-di-n-octyl-dithieno[3,2-b:2',3'-d]silole (dithienosilole,

Scheme II-3: Synthesis routes to obtain precursors for DTS-based target molecules.

Prior to the synthesis of precursors, various fragments displayed in Scheme II-3 need to be synthesized, such as different DTS cores and fragments originated from 2,1,3benzothiadiazole and thiophene (or bithiophene) carboxaldehyde. Due to the high cost of fragment diBrDTS, we planned to synthesize it in our lab although it is commercially available. The proposed synthetic strategies for obtaining DTS cores and Bz-based fragments are presented in Scheme II-4 and Scheme II-5, respectively.

Scheme II-4: General procedure to synthesize the DTS cores for the target molecules.

Scheme II-5: Envisaged synthesis routes for Bz-based fragments via direct arylation.

Fragment diBrDTS can be obtained in three steps, while DTS-(SnBu3)2 and diTDTS can be obtained in one more step. Bz-based fragments (BrBzT1CHO, BrBzT2CHO and BzT2CHO) can be obtained in one step by direct arylation. Then DTS-based cores need to be coupled with these non-symmetrical Bz-based fragments that are not easy to be isolated to achieve target molecules. The details about these syntheses will be given in Chapter III.

II. 3 Small molecules based on subphthalocyanines (SubPcs)

Subphthalocyanines (SubPcs) were discovered coincidentally in 1972 by Meller and Ossko (212) when they were attempting to synthesize boron phtalocyanines (BPcs). SubPcs (185,186,213) as the best known contracted porphyrinoid species, are a novel class of Pcs ( 214) related compounds, comprising three instead of four N-fused diiminoisoindoline units From Table II-2, we can see that SubPcs can function as electron donor with a good efficiency of 3.0% and 4.0% when using C60 and fused fluorinated SubPc dimer (FSubPcDimer, see

Figure as electron acceptors, respectively. SubPcs can also act as electron acceptor with a higher efficiency of 4.69%. When combining SubPcBCl and SubNcBCl as acceptors in a three-layer device, this leads to a remarkable PCE of 8.4%. This is the best non-fullerenebased OPV cell reported up to now, consisting of a SubPcBCl acceptor. a for the detailed donor/acceptor weight ratio in device, see the relevant references.

In summary, inspired by the unique optical and electrical properties of SubPcs and their potential in OPV device, we envisaged to combine fragments BrBzT1CHO and BrBzT2CHO

with phenol-substituted SubPcs (see Scheme . This would lead to a set of novel SubPcs derivatives. The chemical structures and synthesis strategies proposed for SubPcs-based novel molecules are shown in Scheme II-6. More details about the synthesis will be described in the next chapter. Once molecules were designed, theoretical calculations were carried out to predict their electronic properties and thus to evaluate their potential in OPV applications.

III Theoretical calculation

Nowadays, molecular modeling techniques and particularly quantum chemistry provide a competitive alternative for interpretation of experimental results, as well as for molecular design through the prediction of optoelectronic properties. The density functional theory (DFT) (184) method and time-dependent DFT (TD-DFT)(266-268) can offer a good treatment of the electron correlation effects, therefore, compare very well with the experimental results.(269, 270) Thus, to further predict the electronic properties of all designed molecules aforementioned, we conducted all the calculations using DFT method at the B3LYP/Def2-TZVP(-f) level. To facilitate the computation, the terminal octyl or 2-ethylhexyl chains were replaced by methyl groups.

III. 1 Bz-based small molecules

III. 1-1 Electronic and optical properties

To ensure that optimized geometries of Bz-based small molecules will be the most stable conformation, the core fragment (4,7-dithieno-2,1,3-benzothiadiazole, diTBz) was first optimized with different configuration (see Figure . From the energy listed in Table II-3 Figure II-13: The scheme of dihedral angles for structural analysis.

The dihedral angles (θA, θB, θC, θD) are defined as the dihedral angle for adjacent rings. The dihedral angles for Bz(T1CAMe)2, Bz(T2CAMe)2 and Bz(T3CAMe)2 are in the range of 1-6°, suggesting their good coplanarity. It indicates such nearly planar geometry is favorable to the π electron transfer from the electron-donating unit to electron-withdrawing moiety. Note that here the dihedral angle values (italic) for Bz(T4CAMe)2 are not strictly accurate because here the geometry optimization of Bz(T4CAMe)2 is not totally achieved (as there is one imaginary frequency), although it shows good coplanarity. Due to the large molecular system of Bz(T4CAMe)2, the computation is time-consuming, thus the further optimization is so far not finished yet. In addition, to synthesis ter-thiophene and quater-thiophene fragments, at least one or two more steps will be needed from the commercial reagent, which will cause difficulty in the synthesis. Thus we do not envisage to synthesize Bz(T3CAMe)2 and Bz(T4CAMe)2. and Bz(T2CAMe)2 are distributed almost entirely over the conjugated molecule that adopts an aromatic character, which is beneficial for obtaining high charge mobility. The LUMO of Bz(T1CAMe)2 and Bz(T2CAMe)2 are slightly concentrated on benzothiadiazole unit in the two species with a quinoid character. However, for Bz(T3CAMe)2 and Bz(T4CAMe)2, their HOMO orbitals are more concentrated in the central part of the backbone, while their LUMOs are more localized on the benzothiadiazole and cyano groups. This phenomenon could be interpreted as the effect of the torsion in their geometries. Besides, we can observe that from Bz(T1CAMe)2 to Bz(T4CAMe)2, with the increase in the conjugation length, the HOMO and LUMO energy levels are increased simultaneously. The increased degree of HOMO energy levels is larger than that of LUMO, which leads to lowering trend in the band gap. Note that although the nature of the optimized Bz(T4CAMe)2 was not checked, it is expected that the electron density distribution of its frontier molecular orbitals and the general trend in energy levels and energy gaps from Bz(T1CAMe)2 to Bz(T4CAMe)2 will not be affected. The ΔE values for the four molecules are all larger than 0.3 eV, which is an encouraging parameter for charge separation upon electron transfer from donor to acceptor.

Table II- shows that the theoretically most stable conformation, for diTffBz, is trans-trans, like for the previously studied diTBz. One can also observe that the di-fluorination of diTBz unit reduces both HOMO and LUMO energy levels but widen the energy gap, which is in good agreement with the experimental results reported by Son et al.(278). Like it is the case for Bz(T1CAMe)2, Bz(T2CAMe)2, and Bz(T3CAMe)2, the dihedral angles for ffBz(T1CAMe)2, ffBz(T2CAMe)2 and ffBz(T3CAMe)2 are in a reasonable range of 1-8°, suggesting good coplanarity. It indicates that such good coplanarity is benefit for the π electron transfer from the electron-donating unit to the electron-withdrawing moiety. On the contrary, the large dihedral angles observed for ffBz(T4CAMe)2 reveal obvious torsion in the geometry due to the elongated chain. Similarly, like it is the case for Bz(T3CAMe)2 and Bz(T4CAMe)2, we do not envisage to synthesize ffBz(T3CAMe)2 and ffBz(T4CAMe)2 due to the difficulty in their synthesis. Table II-7. From these results, it is apparent that the modeled structures of DTS molecules are relatively planar, the dihedral angles between the constituent rings is generally low. This is certainly related to the π-conjugated A-D structure of these compounds. The frontier molecular orbitals and electronic properties of molecules DTS(BzT2CAMe

θ A θ B θ C θ A θ B θ A θ B
electronic parameters of these compounds were also evaluated. It turns out that the energies of their frontier orbitals are very close, in the order of -5.35 eV for the energy of the HOMO and -3.6 eV for the energy of the LUMO. These values are very close to those of an ideal donor, according to the Scharber model, which indicates that the optimized energy values of HOMO and LUMO are -5.4 eV and -3.9 eV, respectively. [START_REF] Thompson | Polymer-Fullerene Composite Solar Cells[END_REF][START_REF] Zhou | Rational Design of High Performance Conjugated Polymers for Organic Solar Cells[END_REF] In addition, the calculation shows that these molecules have a narrow gap in the order of 1.8 eV. Such low energy gap means they may exhibit wide absorption extended to Infrared -Near Infrared region, which is of great significance for the photovoltaic effect. Our DTS-based target molecules may act as electron donors with PCBM as acceptor and may guarantee good performances for OPV cells.

These results encourage us therefore to continue this work by carrying out the synthesis of these molecules. To understand the interaction between the macrocycle of SubPcs and axial substituents, these lasts (see Figure were also studied by DFT. alkyl cyanoacetate group, lowering energy gap of approximately 0.2 eV. This is owing to the spatial electron delocalization that helps to stabilize the molecule. In addition, combing these substituents to phenoxy-SubPc and their respective SubPcs derivatives, for instance, PBrBzT1CHO, phenoxy-SubPc and SubPc-PBrBzT1CHO, the energy levels of SubPc-PBrBzT1CHO are higher than those of substituents but lower than those of phenoxy-SubPc, and the energy gap of SubPc-PBrBzT1CHO (2.67 eV) is lower than both the substituent (2.82 eV) and phenoxy-SubPc (2.72 eV). It again reveals that there may be intramolecular interaction between the axial substituent and the macrocycle of SubPcs, which contributes to stabilize both of them. Generally, peripheral substitution on SubPcs has influence on the electronic characteristics of macrocycle in SubPcs, and it is rarely seen that axial substitution exhibits effect on the electronic properties of SubPcs.(185, 186) Based on our theoretical studies, it reveals that our designed SubPc-based molecules exhibit different and original electronic properties, which will be interesting for further study in the field of SubPcs.

IV Conclusion

To summary, three different series of small molecules were designed and theoretically studied via DFT computations at B3LYP/Def2-TZVP(-f) level. Their geometries and electronic properties were investigated. For Bz-based molecules, the lower the conjugation length is, the flatter the structure is. The optical and electronic band gaps decrease when the conjugation length increases. For DTS-based molecules, they show quite low band gaps of about 1.8 eV.

Our proposed axial substituents make the target SubPcs-based molecules innovative components with original behavior for organic electronics. Given the resultant energy level diagram of these new designed molecules, it implies that they all may be promising candidates for use as active materials for organic photovoltaics applications. We should keep in mind that the LUMO offset should be larger than 0. From synthesis point of view, Bz-based molecules could be obtained in two steps, DTS-based molecules could be obtained in at least three steps in the case of using the commercial fragment diBrDTS, and SubPc-based molecules could be obtained in more than four steps.

Both DTS-and SubPcs-based molecules need non-symmetrical intermediates to be synthesized, which make their syntheses more difficult. Thus, we planned to synthesize Bzbased molecules first, then DTS-based molecules, finally SubPcs-based molecules. The details about their syntheses will be presented in the following chapter. (A) are simple units usually associated with good conversion yields. [START_REF] Chen | Development of Novel Conjugated Donor Polymers for High-Efficiency Bulk-Heterojunction Photovoltaic Devices[END_REF][START_REF] Park | Bulk heterojunction solar cells with internal quantum efficiency approaching 100%[END_REF][START_REF] Peet | Efficiency enhancement in low-bandgap polymer solar cells by processing with alkane dithiols[END_REF]127,203,204,(300)(301)(302) These fragments are aimed at being connected together by coupling reactions.

In this context, we propose here to use an environmentally attractive coupling procedure without polluting wastes in a cost-effective way in comparison to the other existing procedures.

II Synthesis of benzothiadiazole (Bz) based small molecules

The basic idea of this study is to provide small, as simple as possible molecules obtained after as few synthetic steps as possible, from commercially available raw materials. The need of two steps is believed to be the minimum reachable path, leading to the fewest waste production and lowest cost. 4,7-dibromobenzo-2,1,3-thiadiazole (diBrBz) acts here as the electrophile on both sides, in reaction with thiophene carboxaldehyde which is found here to This "ligand-free" strategy was first proposed by Doucet and co-workers (289) who obtained high yields using only 0.1-0.001 mol% catalyst. Such low quantities of catalyst are impossible to weigh accurately in our conditions due to the too low quantities of reactants, so we employed slightly higher relative amounts of palladium acetate. In presence of 0.25 and 0.5 mol% catalyst and of 2 equivalents of potassium acetate relative to diBrBz, the desired product was synthesized in 73% and 71% yield, respectively. Note that once again, the workup of the reaction is extremely easy, as it consists only of filtration, then washing with water, ethyl acetate, and petroleum ether. It is worth noting that only the desirable coupling product resulting from C-H cleavage on the 5-position of 2-thiophene carboxaldehyde was found.

Moreover, no arylation of the acetyl function was observed as this was the case for the In contrast, the batch with molecule TCHO resulted only in black degradation products:

thiophene carboxaldehyde is indeed unstable under direct arylation conditions and must be employed in such conditions that it reacts quickly and completely. This is the reason why we tested the reaction of direct arylation of diBrBz with TCHO in default in Route c (see experimental section). When TCHO is used in 0.9 eq and even down to 0.5 eq with regard to diBrBz, then the yield (calculated with respect to the limiting reactant) is quantitative, and no degradation product is produced. It is worth noting that the purification of the molecule is very easy, driven by simple washing with water to eliminate KOAc and KBr, ethyl acetate to eliminate Pd(OAc)2, and finally petroleum ether to help in eliminating AcOEt and remaining DMA. The ease of purification is undoubtedly linked to the cleanliness of the reaction that does not generate side products.

The two routes used for obtaining the elongated intermediate Bz(T2CHO)2, documented in the experimental section are summarized in Scheme III-4.

Scheme III-4: Classical (top) and new (bottom) routes to molecule Bz(T2CHO)2.

As described above for the synthesis of Bz(T1CHO)2, Bz(T2CHO)2 was obtained in quantitative yield by Suzuki coupling (Route a), using the same synthetic procedure. Route c was then directly tested by reacting T2CHO and diBrBz in the ratio of 2.2:1 as for molecule Bz(T1CHO)2. In this case, molecule Bz(T2CHO)2 was obtained with an excellent yield of 92% which was not further investigated. The improved yield is attributed to the greater reactivity of molecule T2CHO towards the coupling compared to that of molecule TCHO and to the lower solubility of Bz(T2CHO)2 with respect to that of Bz(T1CHO)2.

The Knoevenagel condensation is driven in a classical manner. Most of organic molecules for organic electronics are purified by means of column chromatography. Here, it is noteworthy that the target molecules are purified by simple recrystallization in ethyl acetate, reducing the waste problem originated from the synthesis procedure. All the target molecules were fully characterized and their structures are confirmed by different analytic tools (elemental analysis, NMR, MS) which are summarized in experimental section.

II. 1-2 Environmental and economic aspects

Among the aspects of importance for OPV (efficiency, stability, printability), materials for large-scale production should be as inexpensive as possible. The cost trends of 20 €/g for the upscaling scenario and 10 €/g for the industrial scenario have been recently suggested.(310)

The materials synthesis must be realized from commercially available chemicals in few steps and with straightforward purification procedures.(133) Overall yields and E-factor (defined by the ratio of the mass of waste per unit mass of product) are quantifiable green metrics used for evaluating the environmental impact associated with the production of organic materials for sustainable applications.(311, 312) These metrics for the molecules elaborated in this work have been evaluated (see Table III-1 and Annexes 6 for details).

(a) Molecule Bz(T1CHO)2 obtained via Routes a, b, and c

The three synthesis protocols described above (Scheme III-1, Scheme III-2 and Scheme III-3)

have been compared for the synthesis of molecule Bz(T1CHO)2. As can be seen in Table III-1, the calculated E-factor and price of Bz(T1CHO)2 (see Annexes 6) show dramatic change from one route to another. The atom economy is calculated as the ratio of the mass of the desired product to the mass of the reactants. Surprisingly, the E-factor calculation for Route b affords a value very close to that calculated for Route a. This is due to the consequent amount of catalyst (10 mol% Pd(OAc)2) and ligand (20 mol% P t Bu2Me.HBF4) used for the direct arylation which is revealed here to be less eco-friendly than the Suzuki coupling. On the other hand, Suzuki coupling involves expensive raw materials which increase the cost of Bz(T1CHO)2. A consequent improvement of the green metrics is obtained when direct arylation without ligand (Route c) is carried out. This process involves a low amount of catalyst (0.5 mol% palladium acetate) and the absence of any additive, resulting in a very simple protocol with an E-factor of 143g/g, which is approximately one third of that obtained from the two other routes. Moreover, the cost of Bz(T1CHO)2 becomes nearly one twelfth and one third of that resulted from Route a and Route b, respectively. This represents a great improvement in term of waste production and cost for the synthesis of the same intermediate. In addition, the atom economy of Route b and c are higher than that of Route a, suggesting that the direct arylation is greener than the traditional Suzuki coupling. The difference in atom economy between Route b and Route c is attributed to the yield.

(b) Molecule Bz(T1CHO)2 obtained via Route c and different ratios (r)

We then examined if it was possible to improve the Route c metrics by increasing the yield of the reaction. For achieving better yields and decreasing the amount of degradation products associated with side reactions experienced by TCHO, the molecular ratio between TCHO and diBrBz was lowered to 0.9, then 0.5 (instead of 2.2). The obtained values are gathered in For the synthesis of Bz(T2CHO)2, the calculated green metrics for Route a and Route c confirmed the previous trends (see : the E-factor calculation for Route c returned a value of 76 g/g, which was around one-sixth of that found for Route a, and the cost was reduced by a factor 5 between Route a and Route c. It is worth noting here that for Route c, the molecular ratio T2CHO/diBrBz ratio (r) was 2.2.

Route a Route c

Yield (%) 100% 91%

E-factor (g/g) 497 76

Cost (€/g) 201 40

Atom economy 48% 66%

From the aspect of atom economy, it is obvious that the Route c is greener than Route a, which is also consistent with the E-factor. It confirms that ligand-less direct arylation is a greener procedure. Among the four products identified in the crude sample, there was always an excess of diBrBz making the isolation of the mono-substituted product very difficult. It seems that diBrBz is poorly reactive. We even tested synthesis at room temperature, to reduce or avoid the formation of di-substituted molecule Bz(T1CHO)2, but it was still found in the crude product, as proved by 1 H NMR analysis. Another issue was the large quantity of TCHO also identified by 1 H NMR spectroscopy in the crude product. We can infer that diBrBz is very stable under Suzuki reaction and undergoes very slow additive oxidation during the catalytic cycle, while the transmetallation of the borate of the thiophene moiety takes place more rapidly (the catalytic cycle of Suzuki cross-coupling reaction is given in Annexes, on Figure NMR analysis of the crude product. At the best, a 22% yield in non-isolated product was reached by using the following conditions: the molar ratio of 2-thiophenecarboxaldehyde (500 mg, 1.7 mmol, 1eq)/4,7-dibromobenzo-2,1,3-thiadiazole is 0.7, the amount of ligand (P t Bu2Me.HBF4) and additive (pivalic acid) is 10 mol% and 30 mol% (relative to diBrBz), respectively; fixed amount of potassium carbonate (K2CO3, 705 mg, 3eq) and palladium acetate (Pd(OAc)2, 38 mg, 10% mol) (relative to diBrBz), 7.5 mL dry toluene under an argon atmosphere in a three-necked flask and refluxed for 18h.

In order to improve the yield of this mono-coupling reaction, lots of efforts were made to optimize reaction conditions, such as playing with the TCHO/diBrBz ratio, the amount of catalyst and base, various temperatures and time of reaction. The relevant details in synthesis of fragment BrBzT1CHO via various conditions are summarized in the experimental section (Table V-3 and V-4). Like it was the case for Suzuki reactions, mainly four products were identified in the crude mixture: diBrBz, molecule Bz(T1CHO)2, BrBzT1CHO and TCHO. It is worth to note that the non-reacted starting materials can be recovered. First, Route c was carried out at temperature of 105°C, 115°C, 125°C and 140°C (oil bath, the temperature of the reaction mixture is at around 10°C below) (see Table V -3). Note that when the temperature of the oil bath reached 140°C, only di-substituted product was formed. We reached a 20% of non-isolated product at best at 115°C. Thus, various procedures were carried out at a maximum temperature of 115°C (oil bath) (see Table V -4). The best obtained result was 35% yield of isolated product, which was obtained via Route c under the following condition:

molar TCHO/diBrBz ratio of 0.5, 1.5 equivalent of potassium acetate (KOAc) and 1 mol% catalyst palladium acetate (Pd(OAc)2) (relative to diBrBz), 6 mL DMA and stirring at 105 °C for 21 h under an argon atmosphere in a three-necked flask. As a 30% yield of isolated product was obtained via Route a as mentioned above, thus, direct arylation is comparable to the traditional Suzuki coupling method. Taking into account the environmental factors, direct arylation (especially Route c) is preferable in that case, and this fully validates our efforts in optimizing the direct arylation method.

In order to increase more the yield in mono-substituted compounds via Routes b and c, another protocol was designed and carried out, as displayed in Scheme III-6. But this time, the reactants were changed into 4-bromobenzo-2,1,3-thiadiazole (BrBz) and 5-bromo-2thiophenecarboxaldehyde (BrTCHO). The reaction conditions were based on the optimal conditions found for syntheses of molecules Bz(T1CHO)2 and Bz(T2CHO)2. The protocol was tested with a molar ratio of 1:1 between BrBz and BrTCHO under Routes b and c given in Scheme III-6. Unfortunately, the 1 H NMR analysis showed only reactants in the crude samples.

Scheme III-6: Other protocols to obtain fragment BrBzT1CHO.

In conclusion, we have tested Suzuki and direct arylation coupling procedures with many different operating conditions. The best yield in isolated product is 35% by using Route c.

Therefore, the Route c is best coupling protocol for the formation of new C-C bond throughout our work.

III. 1-2 Synthesis of fragment BrBzT2CHO

Inspired by previous work, we also tried to synthesize 5'-(7-bromo-2,1,3-benzothiadiazol-4yl)-[2,2'-bithiophene]-5-carboxldehyde (BrBzT2CHO) via Route c. The best way for obtaining BrBzT1CHO was directly applied to the present case, as presented in Scheme III-7.

The only difference was the T2CHO/diBrBz molar ratio which was fixed at 1 instead of 0.5.

Scheme III-7: Synthetic route to obtain fragment BrBzT2CHO.

Similar to the case of BrBzT1CHO, mainly four products were identified in the crude mixture, consisting of diBrBz, T2CHO, BrBzT2CHO and di-substituted molecule Bz(T2CHO)2. They were detected by TLC under UV lamp and their ratio was able to be analysed by 1 H NMR spectroscopy. Based on the experience for purifying fragment BrBzT1CHO, the crude product was subjected to flash chromatography to isolate very pure mono-arylated BrBzT2CHO in 8% yield. This result was reproducible. In spite of the fact that the yield was not optimistic, the isolated mono-substituted product was very pure. This very pure fragment BrBzT2CHO would be very advantageous for the further synthesis of DTS-based target molecules. Once these fragments were obtained, they could be coupled via either direct arylation or Stille coupling, forming DTS-based precursors (see Scheme II-3 in Chapter II). Synthesis via direct arylation is a preferable approach throughout this project. Then these precursors will be engaged in Knoevenagel condensations to yield a series of the target DTS-based molecules (see Scheme II-2 in Chapter II). To fulfil these aims, the first strategy was to couple fragment diBrDTS with BzT2CHO under different direct arylation conditions that are proven to be very effective, for obtaining the di-substituted molecules Bz(T1CHO)2 and Bz(T2CHO)2. Two tested reactions are given in Scheme III-10.

Scheme III-10: One strategy supposed to obtain DTS(BzT2CHO)2.

However, neither of the reactions worked, only both of the starting materials were found in the crude mixture as proved by 1 H NMR analysis. Since the strategy via direct arylation failed, the fragment BzT2CHO was recovered and used for the synthesis of BzT2CAO previously described. It infers that the C-H bond activation is harder to reach on the benzothiadiazole ring than that on the thiophene ring. Thus, we turned to another strategy Unfortunately, this reaction did not work in our case.

Scheme III-12:

The strategy for obtaining DTS(TBzT1CHO)2.

Due to the limited time, further work on DTS(TBzT1CHO)2 was also suspended. More efforts should be devoted to find the optimal direct arylation procedure for obtaining it. Once it will be obtained, followed by Knoevenagel condensation, the target molecule DTS(TBzT1CAO)2

(see Scheme II-2 in Chapter II) will be achieved. Besides, if the strategy for obtaining DTS(TBzT1CHO)2 would be realized, the coupling between fragments diTDTS and BrBzT2CHO would also be achieved and thus similar target molecule DTS(TBzT2CAO)2 (see Scheme II-2 in Chapter II) would be obtained afterwards.

IV Subphthalocyanine (SubPc) derivatives: synthesis and axial substitution

IV. 1 Synthesis of chloroboron subphthalocyanine (SubPcBCl)

SubPcs have become molecular materials in areas of energy and electron transfer, particularly ascribe to their unique optical properties. The chemistry of SubPcs has been well explored over the last two decades because of the great contribution from the teams of Torres (185,186,247,316),Bender (234,250), Hanack (317) etc.. So far SubPcs are only known as boron complex (BSubPcs). The boron atom performed perfectly as the central cavity and efficiently directs the phthalonitrile cyclotrimerization reaction that causes these macrocycles. The general synthesis procedure is typically carried out in the presence of a boron trihalide (BCl3 or BBr3) at high temperature (185,186,234,316,318). As a consequence, a halide atom (Cl or Br) consequently occupies the axial position of the SubPc, forming chloroboron SubPcs (SubPcBCl) or bromine boron SubPcs.

Dedicated efforts have been devoted to the preparation of SubPcBCl. One of major breakthroughs is the Torres group's discovery of a high efficient method for the preparation of SubPcs in high yields.(316) They reported that the experimentally determined optimal stoichiometry between phthalonitrile and BCl3 is 1:1. Another major breakthrough is the development of general methodology for axial substitution in BSubPcs species.(316) Herein, we carried out the following reactions (see Scheme III-13) several times to reproduce the work of Claessens et al.(316) From the results summarized in the experimental section (see Table V-5), a maximum of 47% yield was achieved.

Scheme III-13: Synthesis route to SubPcBCl.

In our work, we did exactly the same treatment as described by Claessens et al.,(316) but the yield (12%) was quite lower than that claimed in their article (82%). Then a little different treatment was tried. We skipped directly to the washing step in place of washing after extraction, and washing, and a moderate yield (47%) was finally obtained using this modified treatment (see experimental section).

IV. 2 Axial substitution of SubPcBCl

SubPcs are synthetically diverse molecules, and their reactivity is presumably classified in mainly three groups: axial reactivity, peripheral reactivity, and ring expansion reactivity.( 186)

The electronic and physical properties of SubPcs are rather attractive, and they may be welltuned by alternating their axial ligands with certain nucleophiles (247) or by modifying the peripheral substituents at the isoindole rings.

The reactivity at the axial position in SubPcs has been exhaustively investigated for the substitution of these molecules for different aims. To begin with, axial functionalization can help these molecules soluble in water(319) or organic (320) media, which is important for the device processing and biological applications. Furthermore, it has been proved that substitution with some ligands enhances their optical, thermal, and chemical stability (320, 321). Moreover, this axial substitution tolerates for straightforwardly merging these singular chromophores into larger multicomponent and more complex systems without influencing the electronic characteristics of the macrocycles, which are principally evaluated by the feature of the peripheral substituents.(232, 251) Besides, the variation of axial substitution is of great interest for SubPcs chemistry. Among the many possible substituting compounds, phenol derivatives are to date the most widely used reagent for the axial substitution reactions. From the point of experiment, we found that phenol derivatives provide many advantages: (i) phenol derivatives are available in considerable quantities; (ii) the reaction is carried out in a simple and straightforward way and it generally affords moderate to favorable yield. (185,186,316) A recent study showed that over 90% of the research published in chemistry journals on SubPcs involve the synthesis of phenoxy-SubPcs during the last decade.( 186)

Therefore, our study commenced with the axial substitution using phenol, as schemed in Scheme III-14. This work was inspired by the work of Torres et al.(247,316). It was found that the phenol in fivefold excess can give good yields of phenoxy-perfluoroSubPc. Thus the same condition and procedure were applied to our work. The corresponding phenoxy-SubPc was able to be monitored by TLC and 1 H NMR. It was purified by column chromatography in 41% yield.

Scheme III-14: Synthesis route to phenoxy-SubPc.

With regard to synthesized SubPcBCl and phenoxy-SubPc, they were also characterized in term of UV-Vis absorption as well as 1 BrBzT2CHO) were obtained at the moment, the following interesting work hasn't been conducted due to lack of time. Besides, we may encounter difficulties in the following synthesis due to reactivity of the hydrogen on the benzene ring. However, based on our theoretical calculations, once SubPcs-based target molecules were achieved, their interesting electronic properties would make them promising candidates for electron donors or acceptors.

V Conclusion

To conclude, the present study provides chemical synthetic protocols for the synthesis of regioselective D-A based materials in addition to give a general guideline towards the design of benzothiadiazole and thiophene-based materials for the applications in OPVs. As synthetic chemists, our aim is to contribute to develop clean energy using materials that are obtained according to green practices. Five new Bz-based molecules have been synthesized according to green practices. The proposed molecules are unsophisticated and obtained via a synthetic approach that may significantly impact the environmental factors, in term of non-reacted raw materials or waste generation. The ligand-less direct arylation reaction has proved to be a powerful green tool for obtaining dithienylbenzothidiazole blocks, which are very often used as a building block for more expanded materials used in organic electronics. E-factor values below 400 g/g associated with molecules prices in the order of 45 €/g are promising numbers

for potential large-scale applications. Their full characterization will be described in Chapter IV.

Direct arylation method in our work on di-substituted molecules Bz(T1CHO)2 and Bz(T2CHO)2 has exhibited the following advantages over traditional cross-coupling techniques: fewer synthetic steps, higher yields, lower catalyst loadings, no use of organometallic intermediate, and does not require chromatographic purification. The advantages of direct arylation make it an ideal and green strategy for the synthesis of organic electronic materials. It is quite an attractive method that can be added to chemists' toolbox, enabling more effective designation and preparation of highly efficient polymers or small molecules and providing a new vision into promising and novel electrical materials. Syntheses of SubPcBCl and its axial substitution using phenol were studied. Axial substitution using mono-substituted fragments (BrBzT1CHO or BrBzT2CHO) via direct arylation were also envisaged. Due to lack of time, this idea has not yet been explored. Based on theoretical calculations presented in the previous chapter, it is predicted that original electronic properties are awaited for these SubPcs-based new materials that may lead to promising performances in organic photovoltaics, paving the way for innovative materials.

Chapter IV: Materials characterization Chapter IV : Materials characterization

In this section, the obtained and well characterized compounds including Bz(T1CAO)2, Bz(T1CAEH)2, Bz(T2CAO)2 and Bz(T2CAEH)2 are going to be described and discussed in terms of optical and electrochemical properties, thermal properties, structural properties and their potential in organic photovoltaic application. The influence of the different alkyl chains (linear and branched) on these characteristics will also be investigated. For convenience, Bz(T1CAR)2 represents both Bz(T1CAO)2 and Bz(T1CAEH)2, and Bz(T2CAR)2 represents both Bz(T2CAO)2 and Bz(T2CAEH)2. Besides, molecule BzT2CAO was obtained very recently, thus it is not well studied, and here we will just simply discuss its electronic properties in solution.

I Optical properties

The UV-vis absorption of the four molecules in dichloromethane (DCM) solution was recorded at room temperature, as given in and. [START_REF] Liu | Aggregation and morphology control enables multiple cases of high-efficiency polymer solar cells[END_REF]324,325) It also suggests annealing weakens the aggregation effect greatly at elevated temperature due to weaker π-π packing, resulting in less-ordered structure. In particular, annealing at 160°C for 20 min results in almost no aggregation, and the absorption shape is like the one observed from solution. We can conclude that annealing makes morphology of Bz(T1CAEH)2 film less ordered. Thus, annealing is not suitable for our molecules even they are chemically stable until 300°C, although it has been proven to be film with the shoulder at around 584 nm, while the shoulder of P3HT at 605 nm also collapsed. For both blends, their spectra are very close to that of pristine Bz(T1CAO)2 and Bz(T1CAEH)2 thin films but with less-resolved shoulders. It suggests that there is almost no change on the structure of Bz(T1CAO)2 and Bz(T1CAEH)2 but on the structure of P3HT in the blends. We can infer the existence of the interaction between the two compounds (Bz(T1CAO)2 and Bz(T1CAEH)2) and P3HT, and the interaction has much influence on the structure of P3HT but weak influence on the structure of these two compounds. The four molecules undergo reversible reduction and oxidation events. This demonstrates that the reduction and oxidation species are electrochemically stable, a positive feature for their potential operational stability in OPV devices. The highest occupied molecular orbital (HOMO) and the lowest unoccupied molecular orbital (LUMO) values were estimated from the onset voltages of the oxidation and reduction waves, respectively.

As indicated in Table IV- Based on the design rules for donors in BHJ solar cells with regard to Scharber model,( 61

V Conclusion

A series of π-conjugated small molecules were characterized in terms of various measurements. Their strong absorption in the region of 300-700 nm in solution is prerequisite for excitons generation. Their good thermal stability associated with their optoelectronic properties and ability to tolerate electron transfer make them interesting molecules to be tested as electron donors or acceptors in OPV applications. We show that a simple replacement of the branched (2-ethylhexyl) with linear (octyl) chain leads to a drastic change in their intermolecular interaction as supported by SAXS measurements. This property will presumably be beneficial for achieving appropriate thin film morphology (depending on the nature of the alkyl chain) for a given use. In that aim, further investigations on thin films of these molecules are also yet to be carried out to evaluate their potential performance in organic photovoltaics. Works are in progress to test them in these roles.

Differential Scanning Calorimetry, DSC, was performed with a DSC 204 F1 Phoenix ® system (NETZSCH). Samples (2-5 mg) were filled in 30l perforated aluminium pans and measurements were conducted under nitrogen atmosphere. Three different heating/cooling cycles were registered for each sample in temperature ranges situated between 5°C and 250°C with a 10°C/min rate. With the exception of the first thermogram, all the cycles were reproducible. The values reported correspond to those determined from the position of the top of the peaks. ΔH is the enthalpy in kJ.mol -1 associated with each phase transition.

LC textures were acquired with an Olympus BX53 polarized light microscope equipped with a Mettler FP82HT heating stage.

The SAXS patterns were obtained with a transmission Guinier-like geometry. A linear focalized monochromatic Cu Kα1 beam (λ = 1.5405 Å) was obtained using a sealed-tube generator (600 W) equipped with a bent quartz monochromator. In all cases, the crude powder was filled in Lindemann capillaries of 1 mm diameter and 10 μm wall-thickness. The diffraction patterns were recorded with a curved Inel CPS120 counter gas-filled detector linked to a data acquisition computer (periodicities up to 90 Å) and on image plates scanned by STORM 820 from Molecular Dynamics with 50 μm resolution (periodicities up to 120 Å).

The sample temperature was controlled within ±0.01 °C, and exposure times were varied from 1 to 24 h.

II Computational details

Theoretical calculations were performed with Orca code 3.0.( 183) Structural optimizations and subsequent frequency calculations (to confirm that the minimum energy ground state is reached without any imaginary frequency) were carried out using an all electron triple zeta basis set with one polarization functions on H,C,N,O and S atoms (Def2-TZVP(-f)).( 334) The B3LYP functional together with Grimme's D3(BJ)(335, 336) model used to add molecular mechanics damped dispersion was applied for ground states calculation. Vertical excitations were computed with TD-DFT using BHandHLYP functional using the B3LYP optimized ground state structures. This hybrid functional which is Becke's half and half method(337) with LYP correlation,( 338) is particularly well adapted in our case due to the presence of molecular species with delocalized electron. Bulk solvent effect, i.e. CH2Cl2, were included using the conductor like screening model (COSMO).( 339) The terminal alkyl groups were 123 replaced by methyl groups, to gain computational time since experimental data concerning optoelectronic properties of the molecules (see Table IV-1) has been proven to be not affected by this simplification. Absorption spectra were simulated using the orca_mapspc program that applies Gaussian-type lineshape function to the calculated transition with a defined full-widthhalf-maximum of 1200 cm -1 . The nature of the transitions was determined using natural transition orbitals.(272, 340)

III Films elaboration

Electronic grade regioregular P3HT (PlexcoreVR average Mn 54 000-75 000; >98% head-totail regioregular) is purchased from Sigma-Aldrich and PCBM is acquired from LUMTEC (99.5%). ITO was purchased from SOLEMS: reference 1) ITO sol 30/1.1 and 30 ohm/cm 2 . 2)

ITO sol 12/1.1 and 10 ohm/cm 2 , both used as received. All the materials, pristine and blended are dissolved in warm chlorobenzene (50°C) to produce 10 mg/mL concentration solutions.

Solutions are filtered using 0.2 m PTFE filters to remove any soluble aggregates. Films are prepared by spin coating at 1500 rpm for 30 s and then at 2000 rpm for 60s on 120nm thick indium tin oxide (ITO) covered glass substrates. The thicknesses of films were from 50 up to 100 nm. All the thin films were elaborated under clean-room conditions.

IV Synthetic procedure

In this part, the 1 H NMR spectrum was given for Bz-based target molecules and intermediates Bz(T1CHO)2 and Bz(T2CHO)2, not for the rest intermediates.

5,5'-(2,1,3-benzothiadiazole-4,7-diyl)bis-(2-thiophenecarboxaldehyde) -molecule

Bz(T1CHO)2

Route a: All solvents and basic solutions were previously degassed by bubbling through argon for 20 min. 2,1,3-benzothiadiazole-4,7-bis(boronic acid pinacol ester) (247 mg, 0.637 mmol, 1 eq) and 5-bromo-2-thiophenecarboxaldehyde (0.196 mL, 1.64 mmol, 2.5 eq) were placed in a three-necked flask which was brought under an inert atmosphere. Toluene (10 mL), K2CO3 (2.0 M, 5 mL), H2O (4 mL) and Aliquat 336 (4-5 drops) were added and the mixture was vigorously stirred under argon for 10 min at room temperature. Pd(PPh3)4 (45 mg, 2.4 mol%) was then added and the mixture was allowed to react for 24 h at 80 °C. After cooling to room temperature, the solid crude mixture was filtered, washed with distilled water, ethyl acetate, then with a vol 1:1 dichloromethane:petroleum ether mixture. After drying under vacuum, 230 mg of pure product were recovered (quantitative yield).

Route b:

In a three-necked flask containing a stirring bar, Pd(OAc)2 (7.6 mg, 0.034 mmol), P t Bu2Me.HBF4 (16.9 mg, 0.068 mmol), pivalic acid (35 mg, 0.34 mmol), 4,7-dibromobenzo-2,1,3-thiadiazole (100 mg, 0.34 mmol), potassium carbonate (141 mg, 1.0 mmol), and 2thiophenecarboxaldehyde (84 mg, 0.75 mmol) were sequentially added under a flow of argon.

Dry toluene (4 mL) was added and the reaction mixture was heated at 120°C in an oil bath for 5.5 h until judged complete by examining aliquots with TLC. After cooling to room temperature, the solid crude mixture was filtered, washed with distilled water, ethyl acetate, then with petroleum ether. After drying under vacuum, 119 mg of pure product were recovered (98% yield).

Route c:

In a 100 mL three-necked round-bottomed flask, equipped with a thermometer, magnetic stirrer, condenser and rubber seal, 2-thiophenecarboxaldehyde (419 mg, 3.74 mmol, 2.2 eq) and DMA (6 mL) were added to a mixture of 4,7-dibromobenzo-2,1,3-thiadiazole (500 mg, 1.7 mmol, 1 eq), potassium acetate (334 mg, 3.4 mmol, 2 eq), and palladium acetate (1.9 mg, 8.4×10 -3 mmol (0.5%)) in one portion under argon atmosphere. The reaction mixture was then heated to 150°C and stirred under vigorous reflux for 24 h. The dark red solution was cooled to ambient temperature and filtered. After washing with water, ethyl acetate, and then petroleum ether, the corresponding red diarylated product was dried, affording 430 mg of pure product (71% yield). Route a: All solvents and basic solutions were previously degassed by bubbling through argon for 20 min. 2,1,3-benzothiadiazole-4,7-bis(boronic acid pinacol ester) (173 mg, 0.445 mmol, 1 eq) and 5'-bromo-2,2'-bithiophene- 5-carboxaldehyde (305 mg, 1.11 mmol, 2.5 eq) were placed in a three-necked flask which was brought under an inert atmosphere. Toluene (25 mL), K2CO3 (2.0 M, 5 mL), H2O (4 mL) and Aliquat 336 (2-3 drops) were added and the mixture was vigorously stirred under argon for 10 min at room temperature. Pd(PPh3)4 (38.5 mg, 3.0 mol%) was then added and the mixture was allowed to react for 24 h at 80 °C. After cooling to room temperature, the solid crude mixture was filtered, washed with distilled water, ethyl acetate, then with petroleum ether. After drying under vacuum, 230 mg of pure product were recovered (quantitative yield).

Route c:

In a 100 mL three-necked round-bottomed flask, equipped with a thermometer, magnetic stirrer, condenser and rubber seal, 2,2'-bithiophene-5-carboxaldehyde (727 mg, 3.74 mmol, 2.2 eq) and DMA (6 mL) were added to a mixture of 4,7-dibromobenzo-2,1,3thiadiazole (500 mg, 1.7 mmol, 1 eq), potassium acetate (334 mg, 3.4 mmol), and palladium acetate (1.9 mg, 8.4×10 -3 mmol (0.5%)) in one portion under argon atmosphere. The reaction mixture was then heated to 150°C and stirred under vigorous reflux for 24 h. The dark red solution was cooled to ambient temperature and filtered. After washing with water, ethyl acetate, and then petroleum ether, the corresponding red diarylated product was dried, affording 811 mg of pure product (92% yield). stirred for 40 h under argon at room temperature (followed by TLC). After removal of solvent, the obtained powder was washed with distilled water (10 mL), then ethanol (10 mL) and petroleum ether (30 mL), affording Bz(T1CAO)2 as dark solid, then further purified by recrystallization in 20 mL ethyl acetate, giving rise to 460 mg pure black solid (51% yield). was stirred for 29 h under argon at room temperature (followed by TLC). After removal of solvent, the obtained powder was washed with distilled water (10 mL), then ethanol (10 mL) and petroleum ether (20 mL), affording Bz(T2CAO)2 as dark solid, then further purified by recrystallization with 15 mL ethyl acetate, giving rise to 640 mg pure product (76% yield). was stirred for 40 h under argon at room temperature (followed by TLC). After removal of solvent, the obtained powder was washed with distilled water (10 mL), then ethanol (10 mL) and petroleum ether (20 mL), affording Bz(T2CAEH)2 as dark solid, then further purified by recrystallization with 15 mL ethyl acetate, giving rise to 570 mg pure product (68% yield). and gradually rise of the polarity until 1:1) and then on silica gel (petroleum ether: ethyl acetate, from 4:1 until 0:1) to a yellowish orange powder in 10% to 30% yield.

Direct arylation

Route b

The 4,7-dibromobenzo-2,1,3-thiadiazole (500 mg, 1.7 mmol, 1eq), 2thiophenecarboxaldehyde (r eq) where "r" means molar ratios of 2thiophenecarboxaldehyde/4,7-dibromobenzo-2,1,3-thiadiazole, various amount of ligand (P t Bu2Me.HBF4) and additive (pivalic acid) (relative to 4,7-dibromobenzo-2,1,3-thiadiazole), fixed amount of potassium carbonate (K2CO3, 705 mg, 3eq) and palladium acetate (Pd(OAc)2, 38 mg, 10% mol) (relative to 4,7-dibromobenzo-2,1,3-thiadiazole) were dissolved in 7.5 mL dry toluene (fixed parameter) under an argon atmosphere in a three-necked flask. The reaction mixture was refluxed at fixed temperature of oil bath (120 °C) for various reaction times (h).

Then, the solvent was evaporated and the reaction yield was estimated from the1 HNMR spectrum of the crude product. All reaction conditions are resumed in Table V-2.

Route c

i) The 4,7-dibromobenzo-2,1,3-thiadiazole (500 mg, 1.7 mmol, 1eq, fixed parameter), 2thiophenecarboxaldehyde (191 mg, 1.7 mmol, 1eq) (molar ratio of 2thiophenecarboxaldehyde/4,7-dibromobenzo-2,1,3-thiadiazole is 1), potassium acetate (KOAc, 250 mg, 2.55 mmol, 1.5 eq) and palladium acetate (Pd(OAc)2, 4 mg, 1% relative to 4,7-dibromobenzo-2,1,3-thiadiazole) were dissolved in 6 mL DMA under an argon atmosphere in a schlenk. All of these parameters above were fixed. The reaction mixture was stirred at various temperatures (T) X °C for various reaction times (h). Then, the solvent was evaporated and the product was purified in the same way as the Suzuki coupling reaction (column on basic alumina and then on silica gel). The reaction yield was estimated from the *T is the temperature of oil bath.

ii) The 4,7-dibromobenzo-2,1,3-thiadiazole (500 mg, 1.7 mmol, 1eq, fixed parameter), 2thiophenecarboxaldehyde (r eq) where "r" means molar ratios of 2thiophenecarboxaldehyde/4,7-dibromobenzo-2,1,3-thiadiazole, various amount of potassium acetate (KOAc) and catalyst palladium acetate (Pd(OAc)2) (relative to 4,7-dibromobenzo-2,1,3-thiadiazole) were dissolved in fixed amount of DMA (6 mL) under an argon atmosphere in a three-necked flask. The reaction mixture was stirred at different temperatures (T, X °C)

for various reaction times (h). Then, the solvent was evaporated and the product was purified in the same way as for the Suzuki cross-coupling reaction (column on basic alumina and then on silica gel). All reaction conditions are summarized in Table V-3. *T is the temperature of the reaction mixture. Note that the temperature of the reaction mixture is around 10°C below that of the oil bath.

5'-(7-bromo-2,1,3-benzothiadiazol-4-yl)-[2,2'-bithiophene]-5-carboxaldehyde (BrBzT2CHO)

To a 100 mL three-necked round-bottomed flask, containing a thermometer, stirring bar, and condenser, 4,7-dibromobenzo-2,1,3-thiadiazole (0.5g, 1.7 mmol), potassium acetate (334 mg, 3.4 mmol), and palladium acetate (4 mg, 0.017 mmol) were sequentially added and a rubber seal was used to rigorously keep the system anhydrous and under argon atmosphere. Then 2,2'-bithiophene-5-carboxaldehyde (330 mg, 1.7 mmol) and DMA (8 mL) were added to the mixture using syringe under argon atmosphere. The reaction mixture was then heated to 120°C (oil bath) and stirred under vigorous reflux for 24 hours. The red solution was cooled to room temperature and extracted with dichloromethane several times, then organic phase was evaporated, the residues (500-600mg) was subjected to flash chromatography using ethyl acetate and petroleum ether (from 0:1, 5:95; 1:9; 15:85 to 1:4) as eluent, giving rise to the corresponding red (or orange) mono-arylated product (50 mg, very pure, 8% yield)

5'-(2,1,3-benzothiadiazol-4-yl)-[2,2'-bithiophene]-5-carboxaldehyde (BzT2CHO)

To a 100 mL three-necked round-bottomed flask, containing a thermometer, stirring bar, and condenser, 4-bromobenzo-2,1,3-thiadiazole (500 mg, 2.33 mmol), potassium acetate (457 mg, 4.66 mmol), and palladium acetate (5.2 mg, 0.023 mmol) were sequentially added and a rubber seal was used to rigorously keep the system anhydrous and under argon atmosphere. Then 2,2-bithiophene-5-carboxaldehyde (451 mg, 2.33 mmol) and DMA (8 mL) were added to the mixture using syringe under argon atmosphere. The reaction mixture was then heated to 150°C (oil bath) and stirred under vigorous reflux for 18 hours. The red solution was cooled to room temperature and extracted with dichloromethane and then filtered, the solvent was evaporated, then the residues was subjected to flash chromatography directly using ethyl acetate and petroleum (1:4) as eluent, giving rise to the corresponding orange red direct-arylated product (153 mg, 20% yield, very pure). was dissolved in dry CH2Cl2 (45 mL). The mixture was deoxygenated with argon for 20 minutes. Triethylamine (2.17 mL) and octyl cyanoacetate (2.53 mL, 12 mmol) were added successively. The resulting solution was stirred for 25h under argon at room temperature (followed by TLC). After removal of solvent, the resulting mixture was first washed with petroleum ether, then, with distilled water, ethanol and petroleum ether, affording BzT2CAO as red solid, giving rise to red product (415 mg, 68 % yield).

Boron subphthalocyanine (SubPcBCl)

BCl3 (2 mL, 2 mmol or 4 mL, 4 mmol, 1M solution in p-xylene, 1 eq) was added to dry phthalonitrile (256 mg, 2 mmol or 512 mg, 4 mmol, 1 eq) under an argon atmosphere. The reaction mixture was stirred under reflux for X h (or min). The purple solution was then flushed with argon. Treatment: i): The solvent was evaporated and crude product was extracted with toluene, and a purple solid was recovered after removal of the toluene. Then the resultant purple solid was thoroughly washed with methanol and hexane, yielding pure SubPcBCl. ii): The solvent was evaporated and the solid was dried overnight under reduced pressure, and then the crude product was directly washed thoroughly with methanol and hexane, giving rise to pure SubPcBCl. All reaction conditions and different treatment are presented in Table V-5.

Phenoxy-SubPc

SubPcBCl (51.7 mg, 0.12 mmol) and phenol (56.5 mg, 0.6 mmol) were refluxed in dry toluene (2mL) for 5.5 h. The reaction mixture was cooled down to room temperature, the solvent evaporated under reduced pressure and the resulting purple solid was washed with methanol and hexane (herein, 40 mg of pink crude product was recovered) before being subjected to column chromatography on silica gel using toluene/ethyl acetate (20:1) as eluent, giving rise to 24 mg phenoxy-SubPc (41%).

3,3'-dibromo-5,5'-bis(trimethylsilyl)-2,2'-bithiophene(144)

n-butyllithium solution in hexanes (2.5 M) (7.5 mL, 18.7 mmol) was added dropwisely over a period of 1 h to a solution of 3,3',5,5'-tetrabromo-2,2'-bithiophene (4.5 g, 9.3 mmol) in dry THF (110 mL), at -78 °C. The mixture was stirred for 30 min and di-n-chlorotrimethylsilane (3 mL, 23.25 mmol) was added in one portion, then the cooling bath was removed to warm the mixture to ambient temperature. The reaction mixture was stirred overnight, and then poured into water, extracted with diethyl ether. After removal of the solvent, the residue was purified by flash chromatography on silica gel using hexane as the eluent, giving a colourless oil in 50% yield (2.03 g). 1 H NMR (400 MHz, CDCl3) δ 7.17

4,4'-di-n-octyl-5,5'-bis(tributyltin)-dithieno[3,2-b:2',3'-d]silole

To a 100 mL three-necked round-bottomed flask, containing a thermometer, stirring bar, and condenser, 2,6-dibromo-4,4di-n-octyl-4H-silolo [3,2-b:4,5-b']dithiophene (1.0 g, 1.74 mmol) was dissolved in 20 mL dry THF, then the solution was cooled down carefully to -78°C by a acetone-liquid nitrogen bath. Then 1.5 mL n-butyllithium solution in hexane (2.5 M) diluted in 5 mL THF was added drop wisely (last for 2h). After stirring for another 30mins at -78°C, 1.0 mL tri-n-butyltin chloride (1.19g, 3.65mmol) was added in one portion. Subsequently, the cooling bath was removed, and the argon was stopped. The reaction mixture was stirred at ambient temperature for 16h, followed by poured into water (35 mL) and extracted with diethyl ether for three times, affording 2.3 g of a yellow oil as crude product which was not able to be characterized properly. 67%

1 HNMR yield was however estimated from this crude product that was well dried and stored under argon without further purification for future work.

General conclusion and future work

General conclusion

The objective of this thesis was to design and synthesize novel organic small molecules for applications in OPV devices. In this work, various π-conjugated organic molecules were designed and attempted to be synthesized.

A bibliographic review explains the work principle of organic photovoltaics. Then the important parameters for characterizing the performance of an organic solar cell are discussed with standard condition for testing efficiency of OPV cells. Hereafter different types of OPV device architectures are described. Finally, the state-of-the-art electronic materials for OPV devices are discussed. In particular, some representative and promising polymer-based donors, small-molecules based donors, fullerene based acceptors and fullerene-free based acceptors are deeply discussed together with their corresponding performances in OPV devices. It reveals that small molecule semiconductors are emerging and promising candidates for use as active materials in OPV cells.

The second chapter describes the molecular design. A set of small molecules comprised of benzothiadiazole (Bz) core, 4,4'-di-n-octyl-dithieno [3,2-b:2',3'-d]silole (DTS) core, and subphthalocyanines (SubPcs) unit are designed via DFT computations at B3LYP/ Def2-TZVP(-f) level. Their synthetic strategies are also presented. It is anticipated that these designed molecules show promising potential for organic photovoltaic applications.

In the third chapter, the experimental methods for the molecules syntheses are mainly investigated. Three methods are involved throughout this work: traditional Suzuki crosscoupling, Stille cross-coupling and the emerging direct arylation. Particularly, the direct arylation method is emphatically discussed by means of E-factor (g waste / g product) and cost (€/g). It is demonstrated that direct arylation is an attractive green approach for the synthesis of electronic materials. Among all designed molecules, five molecules based on Bz core are obtained. For DTS and SubPc based target molecules, one more step needs done for obtaining the target molecules.

For obtained four small molecules: Bz(T1CAO)2, Bz(T1CAEH)2, Bz(T2CAO)2 and Bz(T2CAEH)2, they are deeply investigated as presented in the fourth chapter. Their optical properties are fully studied in terms of UV-Vis absorption and photoluminescence. The evaluations of their electronic properties are studied by electrochemistry. Then the thermal and structural properties are studied by means of TGA, DSC and SAXS. We identify these molecules as promising materials for applications in OPV cells. Besides, the experimental results are consistent with theoretical calculation, which suggests that using theoretical calculation to design and predict new materials is a good methodology.

In conclusion, this thesis highlights the need to develop new organic electronic materials for photovoltaic applications and the need to develop green synthesis. Three synthetic approaches (Suzuki, Stille and direct arylation) were involved throughout this work. The E-factor is presented for assessing the environmental impact of two manufacturing processes: the emerging direct arylation method versus the traditional Suzuki cross-coupling method. It

shows that direct arylation is a very promising synthetic method for green chemistry. We synthesized new small molecules, Bz(T1CAO)2, Bz(T1CAEH)2, Bz(T2CAO)2 and Bz(T2CAEH)2 for their use in active layers in solution-processed BHJ-OPVs. All four compounds may have the potential of being used as acceptor when blend with P3HT.

Molecules Bz(T2CAO)2, Bz(T2CAEH)2 and BzT2CAO may be potential candidates for use as electron donors with PCBM as the electron acceptor. The effect of alkyl chains on the morphology was also discussed. Further work is needed to better understand and optimize the performance of these materials in OPV devices.

Future work

First, concerning the initial molecules design, as illustrated in chapter II and III, further synthesis needs to be done to obtain corresponding DTS-and SubPc-based target molecules.

Once the target molecules are obtained, various characterizations will be carried out to study their optoelectronic properties, thermal and structural properties together with the morphology study on their thin films. Then, to measure their charge transfer mobilities and to test them in OPV devices will be the final aim.

Second, molecules Bz(T1CAO)2, and Bz(T1CAEH)2 have been tested as acceptor with P3HT

as donor in BHJ-OPV device, which was done by my colleague Dr. Daniel Hernandez Maldonado in collaboration with Dr. Jose-Luis Maldonado's laboratory. Bz(T1CAO)2, and Bz(T1CAEH)2 showed very low efficiencies (less than 0.1%), which may be caused by the annealing process as discussed in chapter IV. Thus, to fabricate devices via vacuum deposition should be performed to improve the device performance. Works in that aim are under progress. To use DIP molecule as additive in order to improve the crystallinity thus to improve the active layer morphology will be another proposal.

Third, apart from Bz(T1CAO)2, and Bz(T1CAEH)2, we have also obtained Bz(T2CAO)2, Bz(T2CAEH)2, and BzT2CAO that need to be further studied. The charge transfer mobilities need to be measured to know if they will behave as electron donors or acceptors. Their thin film morphologies need also to be studied. Finally, we need to fabricate BHJ devices via vacuum deposition and to test their power conversion efficiencies.

In addition, it will be necessary to study the morphology of the BHJ active layer.

The OPV device will be fabricated in Dr. Jose-Luis Maldonado's laboratory (Mexico). The charge transfer mobilities and BHJ device morphology will be performed by Dr. Isabell Séguy from LAAS laboratory and by collaboration with LAPLACE laboratory in Toulouse, respectively. Annex 6

Annexes

E-factor and costs

Prices are calculated from raw materials purchased from Aldrich unless indicated La synthèse des molécules à base de SubPc n'a pas non plus pu être menée à terme. Il s'est avéré que les rendements de réactions annoncés dans la littérature pour la synthèse de la SubPcBCl sont beaucoup plus optimistes que ceux que nous avons pu atteindre en utilisant les protocoles décrits. Nous avons néanmoins pu isoler la SubPcBCl avec un rendement de 12%, puis effectuer la substitution de l'atome de chlore avec un rendement de 41%.

Figure list

Scheme list

CHAPITRE II : CONCEPTION DES MOLECULES

Titre: Design, synthesis and characterization of new organic semi-conductors for photovoltaics

Résumé

Les cellules photovoltaïques organiques sont une technologie prometteuse pour répondre aux besoins futurs en énergie. Elles présentent de faibles coûts de production, peuvent être réalisées sur substrats flexibles et s'intègrent dans des dispositifs légers. Une voie d'amélioration du rendement de photoconversion est la conception de nouvelles molécules actives présentant des propriétés structurales optimisées. Le présent travail s'inscrit dans cette dynamique: sur la base de calculs utilisant la théorie de la fonctionnelle de la densité, de nouveaux semiconducteurs organiques ont été conçus puis synthétisés.

Pour cela, des techniques de synthèses les plus économiques et les moins polluantes possible ont été mises en oeuvre. Ainsi, le couplage du benzothiadiazole avec le thiophène carboxhaldéhyde par hétéroarylation directe sans additif ni ligand est utilisé avec succès pour la première fois selon des techniques de chimie verte. Cinq molécules sont ainsi isolées en seulement deux étapes. L'étude de leurs propriétés optiques et électroniques par différentes techniques spectroscopiques (UV/vis, fluorescence) et par électrochimie, de leurs propriétés thermiques, et de leur aptitude à s'autoorganiser ont permis de révéler leur aptitude prometteuse pour une utilisation en photovoltaïque organique.

Une série de molécules dérivées du fragment dithiénosilole (DTS) ont été également étudiées par calculs de DFT. Les résultats obtenus montrent que ces dérivés présentent des largeurs de bande interdite très faibles, ce qui constitue un atout pour leur utilisation en cellule photovoltaïque. Ces résultats ont par conséquent motivé leur synthèse. Enfin, un travail purement théorique a été réalisé sur des molécules dérivées des subphthalocyanines de bore. Les calculs effectués révèlent des propriétés électroniques originales pour ces nouveaux matériaux qui devraient mener à des performances intéressantes pour le photovoltaïque organique, ouvrant ainsi la voie vers des matériaux innovants et prometteurs.

Mots clés: Semi-conducteurs organiques; photovoltaïque organique; synthèse; caractérisation

Abstract

Organic solar cells appear as a promising technology to meet future energy requirements, owing to their low production costs, their great flexibility and their ability to be integrated into light devices. Currently, they exhibit modest performances in photoconversion, thus new active molecules with optimized structural properties need to be developed. This work comes in that aim: on the basis of theoretical calculations with density functional theory, new organic semiconductors have been designed and synthesized. For this, the more economical and cleaner syntheses techniques have been employed. Thus, the coupling of the benzothiadiazole with thiophene carboxhaldehyde via direct heteroarylation without additive nor ligand is performed with success for the first time. According to green chemistry techniques, five molecules are thus isolated in only two steps. The study of their optical and electronic properties by means of different spectroscopic techniques (UV/vis, fluorescence) and electrochemistry, of their thermal properties, and of their ability to self-organize have revealed their promising abilities for use in organic photovoltaics.

A series of small molecules based on dithienosilole (DTS) core have also been designed via DFT computations. The calculations show their considerable low bandgap. Their syntheses have been conducted. It anticipates their promising potential for organic photovoltaic applications. Finally, a purely theoretical work has been completed on molecules derived from boron subphthalocyanines. The calculations predict interesting electronic properties for these new materials that may lead to promising performances in organic photovoltaics, paving the way for innovative materials.

Keywords: Organic semiconductors; organic photovoltaics; synthesis; characterization

Figure I- 1 :

 1 Figure I-1: World total primary energy supply in 2013, provided by International Energy Agency. Coal: peat and oil shale are aggregated with coal, other: geothermal, solar, wind, heat, etc., are included.(7)

Figure

  Figure I-2: U.S. energy consumption by energy source in 2014. Source: U.S. Energy Information Administration.(11)

Figure I- 4 :

 4 Figure I-4: Device architecture of a bulk heterojunction photovoltaic cell.

Figure I- 6 :

 6 Figure I-6: The latest chart on record cell efficiencies, provided by The National Center for Photovoltaics (NCPV) at National Renewable Energy Laboratory (NREL).(33) Progress in photovoltaic power conversion efficiencies is tracked six monthly by Green et al.[START_REF] Green | Solar cell efficiency tables (version 47)[END_REF]

Figure I- 7 :

 7 Figure I-7: Basic energy level diagram and illustration of energy gap in molecular case of an organic semiconductor.(53)

Figure I- 8 :

 8 Figure I-8: Functional principle of a D/A solar cell.

Figure I- 9 :

 9 Figure I-9: Absorption coefficients of films of commonly used materials are depicted in comparison with the standard AM 1.5 terrestrial solar spectrum (up)(according to Ref.(56)), and the structures of the materials (down).

3

 3 photovoltaic characterization, thus it is important to have a standard reference spectra in order to allow the reproducibility of characterization and comparison of photovoltaic devices from different research laboratories and manufacturers. The standard spectrum outside the Earth's atmosphere that is typically used for power applications of solar cells in space is AM0 (in red on Figure I-10), which has an overall power of 1366.1 W/m 2 . Herein Air Mass (AM) means the proportion of atmosphere that the sunlight must travel through before striking at the Earth's surface (or sea level) relative to its overhead path length, as shown in FigureI-11, and AM is equal to Y/X, namely, AM = 1/cos(θ) (where θ is the angle from the vertical, zenith angle). AM1 refers to the spectrum after passing through the atmosphere (perfectly clear and cloudless sky) at the Earth's surface when the sun is directly overhead (θ = 0°). AM2 corresponds to a solar zenith angle of θ = 60° which is useful to predict wintertime performance of cells in temperate latitudes.

Figure I- 10 :

 10 Figure I-10: Standard Solar Spectra for space and terrestrial use. (Source: pveducation) The standard solar spectrum at the Earth's surface is named AM1.5G (67)(the G represents global and includes both direct and diffuse radiation, in blue on Figure I-10) or AM1.5D (the D means direct and which involves direct radiation only, in green on Figure I-10), where Air mass 1.5 (AM1.5, 1.5 times thickness of Earth's atmosphere normal to Earth's surface)

Figure I- 11 :

 11 Figure I-11: Scheme of the sunlight path length, in units of Air Mass and dependent on the angle from the vertical (zenith angle θ). (Source: pveducation) II. 3-2 Important parameters for OPV efficiency The performance of OPVs is principally characterized by the power conversion efficiency.(13) There are three important photovoltaic parameters for evaluating photovoltaic performance: the open-circuit voltage (Voc), the short-circuit (photo) current density (Jsc), and the fill factor (FF). A typical current density versus voltage curve for a typical bulk heterojunction OPV device (see architecture provided in Figure I-4) in the dark and under illumination is illustrated in Figure I-12. All photovoltaic cells are photo diodes, which are able to create current or voltage from incident light when processing in reverse bias (where the voltage at the cathode is lower than at the anode). In the dark, as the orange dashed line showed in the current density versus voltage (J-V) curve, there is nearly no current flow until forward bias larger than the open circuit voltage are injected. When under illumination, as evidenced by the shift (blue solid line) in J-V curve, power is generated by the device.

Figure I- 12 :

 12 Figure I-12: Current density versus voltage schematic diagram of organic solar cells in the dark and under illumination.

Figure I- 13 :

 13 Figure I-13: Schematic energy level diagram between an ideal polymer and a PC61BM acceptor.(63) The Voc of a conjugated polymer-PCBM photovoltaic cell (see Figure I-13) can be estimated by the Scharber model given the empirical equation:(61) Voc = 1/e (| E D HOMO -E A LUMO |) -0.3 V

Figure I- 14 :

 14 Figure I-14: Efficiency of a D/A OPV cell vs the band gap energy of the donor, and the LUMO offset between the two materials.(79) Figure I-14 provides the efficiency of a D/A OPV cell versus the band gap energy of the donor and the offset between the LUMO of the donor and the LUMO of the acceptor, with the assumption that Voc obeys equation (4).(61) It is of great interest that the efficiency of the

Figure 1

 1 Figure I-15: The architecture structure of (a) bilayer heterojunction and (b) BHJ OPV devices.(84) II. 4-1 Bilayer heterojunction In a bilayer heterojunction device, donor and acceptor materials are stacked sequentially with a planar interface as displayed in Figure I-15a. The photoactive layer is sandwiched between a high work function anode matching the HOMO of donor and a relatively low work function metal cathode matching the LUMO of acceptor, for efficient collection of the corresponding charge carriers. Figure I-16 shows the schematic energy level diagram of an OPV, revealing the anode and cathode work functions. Generally, a transparent indium tin oxide (ITO) (presenting a work function of -4.7 eV) and aluminum (presenting a work function of -4.3 eV)are the most commonly used anode and cathode, respectively.(85) Generally, bilayer heterojunction devices are achieved by vacuum deposition due to the difficulty to find proper solvents for donor and acceptor layers without damaging the D/A interface.[START_REF] Lin | Small molecule semiconductors for high-efficiency organic photovoltaics[END_REF]

Figure I- 16 :

 16 Figure I-16: Schematic energy level diagram of an OPV, revealing the anode and cathode work functions, the HOMO and LUMO offsets (ΔHOMO and ΔLUMO, respectively) and the maximum open-circuit voltage (Voc).(87)

  by producing an intricate interpenetrating network (Figure I-15b), and also provides charge transport paths to facilitate the charge collection at electrodes for achieving photoelectric conversion. A typical BHJ solar cell,(28) as the architecture outlined in Figure I-15b. As for the bilayer case, the active layer is sandwiched between anode and cathode. Holes and electrons are transported to anode and cathode respectively in a standard architecture. As indicated in the schematic energy level diagram of an OPV (see Figure I-16), the anode typically includes a high work function transparent conducting electrode that is coated with a conducting substrate, and adjusted with an interfacial layer favorable to hole selection and/or electron blocking. The most commonly selected materials used as anode are indium tin oxide (ITO) (presenting a work function of -4.7 eV) on glass substrates adjusted with a interfacial layer about 40nm thick based on poly(ethylenedioxythiophene):poly(styrene sulfonic acid)(PEDOT:PSS).(88) These materials are preferable because of their great optical transparency and good charge transport. A low work function metal with an electron selective layer is often selected as the cathode (as revealed in the schematic energy level diagram). The most commonly encountered cathode is aluminum not only due to its low work function value but also high reflectivity.

Figure I- 17 :

 17 Figure I-17: Schematic architecture of an organic tandem solar cell including two subcells with different and complementary absorption spectra.(79)

Figure I- 18 )

 18 Figure I-18), which was studied in 1977 (120) by Hideko Shirakawa, Alan Heeger and Alan MacDiarmid who has been honored with the Nobel Prize in 2000 for their discovery and development of conductive polymers (121, 122). The π conjugation (overlap) along the backbone leads to the formation of π orbital delocalization, relating to the molecular frontier orbitals (HOMO and LUMO) and determining the electronic and optical properties of the molecules or polymers.

Figure I- 18 :

 18 Figure I-18: trans-polyacetylene and its schematic π orbital.

Figure I- 19 :

 19 Figure I-19: Illustration of energy binding mechanism with increase in the conjugation length of the ethylene in polyacetylene.II. 5-2 Optical properties of semiconducting polymersNormally, the sp 2 pz hybridized wave functions of the carbon atoms in repeat unit causes the πconjugated electronic structure of polymers.[START_REF] Heeger | Semiconducting polymers: the third generation[END_REF] 121, 122, 124) As a schematic band diagram shown in Figure I-20(left), semiconducting polymers are depicted in aspects of the energy bands including the orthogonal π-bonds that generated by the pz wave functions and the bonding and anti-bonding σ-bands between neighboring carbon atoms. As provided in Figure I-20(right), the absorption of photons results in the migration of electrons from the valence band (π-band) to the conduction band (π*-band). As a result, mobile electrons and holes, which are responsible for the photoelectric conversion, are generated. The electrons and holes generated on a single chain relax fast to the respective band edges and, accordingly, either form neutral intrachain excitons or recombine when at energy hʋ>Eg. If the electrons and holes are on isolated chains, polarons will be formed due to their self-localization.(121, 122, 124) The π-π* interchain stacking is a key parameter for the wave function of excitons spread onto the adjacent chains (interchain transfer of excitons). The intrachain excitons can migrate, separate to produce polaron pairs on adjacent chains, go through intersystem crossing to the triplet state, or radiatively and non-radiatively decay to ground state.

Figure I- 20 :

 20 Figure I-20: Schematic band diagram for π-conjugated polymers (left) and π-π* interband transition associated with generation of a mobile electron and a mobile hole in the π*-band and π-band respectively (right).(26) II. 5-3 Charge transport mechanism in conjugated polymers The morphology of polymeric materials plays a significant role in charge transport. It is worth noting that the mechanism of charge transport process in polymers is quite complex. Band transport and hopping are the main mechanisms of charge transport in conjugated polymers.(125) Band transport, often called intrachain transport, can be considered as exclusively for intrachain motion, which is the mechanism that should be conceived when considering conjugation. Hopping can be considered for both intrachain and interchain transport.(125) Here, hopping is a process by which charge carriers jump from one monomer or chain to another instead of transport coherently, which is considered to be very important in devoting to the charge carrier mobility. It is possible that a mix of band transport and hopping occurs in conjugated polymers (see Figure I-21b). It should also be noted that hopping can exhibit intrachain transport, as sketched in Figure I-21a. A defect or kink in a conjugated polymer will create the chance for charge to travel from one part of a chain to another without moving along the chain. Similarly, some non-conjugated materials show good semiconducting behavior with charge transport being exclusively owing to hopping.(125) Poly (vinyl carbazole) may be the simplest case of a polymer of which the charge transport mechanism is exclusively hopping (Figure I-21c).

Figure I- 21 :

 21 Figure I-21: One difference of hopping transport from coherent (band) transport is that there is no need for charge carrier to move from one unit to the next. (a) This involves intrachain transport that may occur by a hopping mechanism, particularly when defects are existed in the chain. (b) It is possible that both coherent transport and hopping can occur in conjugated polymers, with the charge carrier hopping from one chain to another. (c) Only hopping transport exhibits in some polymers like poly(vinyl carbazole), due to lack of conjugated backbone.(125) II. 5-4 Polymer-based and small molecule-based materials for OPV

Figure I- 22 :

 22 Figure I-22: Structures of some (a) electron donor and (b) electron acceptor units.

Figure I- 23 :

 23 Figure I-23: Chemical structures of representative polymers acting as donors in OPV devices.

Figure I- 24 :

 24 Figure I-24: The development of heterojunction solar cells based on polymers and small molecules.(30)

  Figure I-22 provides several representative small molecularbased donors that show good performance in BHJ devices, their chemical structures are given in Figure I-25.

Figure I- 25 :

 25 Figure I-25: Chemical structures of representative small molecular-based donors.

Figure I- 27 :

 27 Figure I-27: Chemical structures of fullerene-free acceptors for OPVs.

  blocks and bonding rules (see Figure, which were chosen with potential and feasibility following the advice from Zhenan Bao group at Stanford University.

Figure II- 1 :

 1 Figure II-1: The 26 building blocks (including chemical connections indicated by 'X') of the resulting CEP molecular candidate library. Five most efficient moieties in the top PCE are highlighted in green, and red indicates the five less efficient moieties.(188) The performance of the top virtual candidates built from the building blocks marked in red and green in Figure II-1 with predicted PCE ≥10% are given in Figure II-2. It reveals that these top candidates comprised of the five most efficient fragments have the highest efficiencies compared to those of most other fragments, while those comprised of the five less efficient moieties lead the lowest performances.

Figure II- 2 :

 2 Figure II-2: Ranking of building blocks related to calculated PCE ≥ 10%.(188) It is worth mentioning that the candidates in the CEP were assessed and ranked by means of the Scharber model (61), a specialized version of the Schockley-Queisser model (193) for OPV donor material performance prediction. Top candidates are in a list of candidates with

Figure II- 3 :

 3 Figure II-3: Chemical structures of some top candidates gathered in the CEPDB.In general, the top candidates in the CEPDB are comprised of fused rings which would offer rigid structure, but their non-symmetrical structures will make the synthesis difficult. Of the 26 building blocks shown in Figure II-1, the building block 15(4,7-dibromobenzo-2,1,3-

  Figure II-4: Pentacene-C60 bilayer interface simulated by molecular dynamics.

Figure II- 5 :

 5 Figure II-5: Chemical structures of designed small molecules based on Bz core.

  DTS) is a well-known electron-rich unit used for developing efficient organic photovoltaic cells, attributed to its highly planar geometry and good electron-donating ability.(206-209) Yang et al. demonstrated that the 4-coordinate Si atom allows for incorporation of aliphatic side chains to guarantee the solubility of small molecules in organic solvents.(144) Figure II-6 shows chemicals structures of some small-molecule donors based on DTS unit, their corresponding electronic properties and OPV performance are given in TableII-1.

Figure II- 6 :

 6 Figure II-6: Chemical structures of some donor materials based on DTS core (C8 = octyl).

  pyridine (PT) unit and fluorinated Bz unit) are linked through the DTS central block, and hexylsubstituted bithiophene are incorporated as the end-capping units, formatting a framework of D-A-D-A-D structure. This D-A-D-A-D structure contributes to strong intramolecular charge transfer characteristics and thus broad optical spectrum. From DTS(PTTh2)2 and p-DTS(FBTTh2)2, the fluorination simultaneously raises the HOMO and LUMO energy levels and increases the band gap (see Table

  Scheme II-2: Chemical structures of designed target molecules based on DTS core.To obtain these DTS-based target molecules, first we need to find appropriate intermediates.As evidenced by Scheme II-3, different precursors, such as DTS(BzT2CHO)2 and DTS(TBzT1CHO)2 are necessary to be obtained. The reactant 4,4'-dioctyl-5,5'-dibromodithieno[3,2-b:2',3'-d]-silole (diBrDTS) is commercial. The DTS(BzT2CHO)2precursor could be obtained within two steps and via direct arylation: the first step consists of the coupling between 4-bromo-2,1,3-benzothiadiazole (BrBz) and 2,2'-bithiophene-5carboxaldehyde (T2CHO), which are both commercial, leading to fragment BrBzT2CHO; the second step consists of the coupling of the diBrDTS core with the previously obtained BzT2CHO fragment (see Scheme II-3 top). DTS(BzT2CHO)2 could be also obtained within three steps, the two last belonging to Stille coupling: the first step is the direct arylation leading to fragment BrBzT2CHO; the second step is the reaction between diBrDTS and tri-n-

  photovoltaic cells,[START_REF] Cnops | 8.4% efficient fullerene-free organic solar cells exploiting long-range exciton energy transfer[END_REF][START_REF] Mutolo | Enhanced Open-Circuit Voltage in Subphthalocyanine/C60 Organic Photovoltaic Cells[END_REF](216)(217)(218)(219)(220)(221)(222)(223)(224)(225)(226)(227)(228)(229)(230)(231) as novel and efficient light-harvesting units for artificial photosynthetic systems,(232) organic light-emitting diodes,(233-236) organic field effect transistors (OFETs),(237-240) optical information recording media.(241-245) Moreover, the unique electronic and optical properties displayed in SubPcs have been demonstrated to exhibit a significant extinction coefficient (k, associated with complex refractive index ñ = n -ik) up to 1.6 at 590 nm in sublimated films, and promising power conversion efficiency of 3.0% have been proved in OPVs.[START_REF] Mutolo | Enhanced Open-Circuit Voltage in Subphthalocyanine/C60 Organic Photovoltaic Cells[END_REF] 218)

Figure II- 8 :

 8 Figure II-8: The axial and peripheral positions on SubPcBCl. (white sticks: H; grey sticks: C; blue sticks: N; yellow sticks: B; green sticks: Cl).(221)Apart from the outstanding electronic properties, SubPcs display multiple options for functionalization at the axial(219, 234, 247, 250) or peripheral positions(185, 186, 216, 234, 248) (see FigureII-8). As a consequence, peripheral substituted SubPcs have significant influence on the electronic characteristics of macrocycle, and it is worth mentioning that their nature, with respect to that of axial groups, induces the most relevant impact on the stability of the SubPcs materials exposed to sunlight.(186) The presence of π-conjugated functional groups or electron-rich or electron-deficient groups on the isoindole rings significantly affects the location of the frontier orbital levels (HOMO-LUMO), thus as a consequence, the Q-band absorption and emission maxima, and the redox potentials.(234, 251) On one hand, it has been demonstrated that SubPcs can function as energy donors (252-255) or energy acceptors(256), or function as electron donors or acceptors in D-A systems(249, 257). On the other hand, SubPcs show low tendency to aggregate in solution because of their non-planar structure. Nonetheless, it is easy to tailor the redox and excited states of these molecules, so that SubPcs can play various roles in electron/energy donors or acceptors in artificial photosynthetic systems.(232, 249, 252, 255,(257)(258)(259)(260)(261)(262)(263)(264)(265)

Figure II- 9 :

 9 Figure II-9: Chemical structures of some materials associated with SubPcs in OPV application.

6 :

 6 Scheme II-6: Designed SubPcs derivatives and synthesis strategies via axial substitution.

Figure II- 10 :

 10 Figure II-10: Conformations of diTBz characterized by dihedral angles (θA and θB).Orbital energy levels and dihedral angles of diTBz in different conformation are also listed in TableII-3. Their energy levels are very close to each other, with slightly deviation in the range of 0.03-0.05 eV. Trans-trans conformation shows the lowest energy gap and smallest dihedral angles, revealing that trans-trans conformation is theoretically easier for electron transfer along the backbone chain compared to trans-cis and cis-cis conformations. It reveals that the trans-trans conformation is the good choice in our related calculations.

Figure II- 11

 11 Figure II-11 displays the frontier orbitals of diTBz in different conformations. It shows no difference in the electron density distribution among the three conformations. The HOMO is delocalized over the whole molecule, while the LUMO is localized on the electron-accepting Bz unit.

Figure II- 11 :

 11 Figure II-11: Frontier molecular orbitals of diTBz in different conformations at the B3LYP/Def2-TZVP(-f) level.

  For the Bz-based small molecules, named as Bz(T1CAEH)2, Bz(T1CAO)2, Bz(T2CAEH)2, Bz(T2CAO)2, Bz(T3CAEH)2, Bz(T3CAO)2, Bz(T4CAEH)2 and Bz(T4CAO)2 (see Figure, replacing terminal octyl or 2-ethylhexyl chains by methyl groups leads to the newly named Bz(T1CAMe)2, Bz(T2CAMe)2, Bz(T3CAMe)2 and Bz(T4CAMe)2 (see Figure.

Figure II- 12 :

 12 Figure II-12: Structures of designed molecules with different conjugation lengths.

Figure II- 14 :

 14 Figure II-14: Frontier molecular orbitals of Bz(T1CAMe)2, Bz(T2CAMe)2, Bz(T3CAMe)2 and Bz(T4CAMe)2 in their optimized geometries at B3LYP/Def2-TZVP(-f) level.To obtain further insights into the effect of molecular structure and electron distribution on the electronic characteristics, calculations of the electronic structure of molecules Bz(T1CAMe)2 and Bz(T2CAMe)2 in excited states were performed with the help of Prof.Fabienne Alary. Because molecules Bz(T3CAMe)2 and Bz(T4CAMe)2 are much larger, to perform TD-DFT calculations on them will be very time-consuming, and it is not necessary to synthesize them, therefore, they were not further studied by TD-DFT. The Natural Transition

Figure II- 15 :

 15 Figure II-15: NTOs isodensity surface for the strongest transition are represented and the associated wavelengths are indicated for Bz(T1CAMe)2 and Bz(T2CAMe)2 in CH2Cl2 at B3LYP/Def2-TZVP(-f) level.

Figure II- 16 :

 16 Figure II-16: Simulated absorption spectra of Bz(T1CAMe)2 (left) and Bz(T2CAMe)2 (right) with different functionals with Def2-TZVP(-f) basis set. As already discussed in chapter I, for OPVs, the energy level of donor HOMO and the energy level of acceptor LUMO should match the anode/cathode to achieve a higher/lower work function, respectively. Meanwhile, the energy difference or offset (ΔE), between the donor LUMO energy and the acceptor LUMO energy should be larger than 0.3 eV, which is the determining driving force required to guarantee efficient charge separation at the D/A interface. The Voc value can be theoretically obtained from the LUMO of PCBM (-4.3 eV)(141), according to the empirical Scharber model.(61) Table II-5 lists evaluated Voc and ΔE predicted with Bz(T1CAMe)2, Bz(T2CAMe)2, Bz(T3CAMe)2 and Bz(T4CAMe)2 as donors associated with PCBM as the acceptor. The calculated Voc values of OPV systems based on these molecules are from 0.77 to 1.7 V. Such large values are of great importance for OPV performance. In particular, Voc predicted with molecules Bz(T1CAMe)2 and Bz(T2CAMe)2exhibit significantly large values (beyond 1.0 V), suggesting that active layers consisting of these components associated with PCBM can be expected to have a potential in OPV devices.

5 : 2

 52 Theoretical open-circuit voltage and energy offset in blends of Bz(Effect of fluorine substitutionSubstitution of carbon or hydrogen atoms with fluorine in D-A based organic molecules has been shown to tune the molecular orbital levels and thus impact on the photovoltaic performance of an OPV device.[START_REF] Wang | Correlating molecular morphology with optoelectronic function in solar cells based on low band-gap copolymer: fullerene blends[END_REF][START_REF] Zhou | Rational Design of High Performance Conjugated Polymers for Organic Solar Cells[END_REF] 127) The introduction of F atom into the conjugated backbone can simultaneously lower the HOMO and LUMO levels, giving only minor changes to the optical band gap.(49) Thus, enhanced stability against photo-oxidation by lowering the HOMO energy level can be achieved. Fluorination of conjugated molecules offers a series of unique features such as great thermal and oxidative stability, elevated resistance to degradation,(273) enhanced hydrophobicity,(274) and high lipophobicity in perfluorinated substances.(275) These features are related to the unique properties of the fluorine atom: first, fluorine atom is the smallest electron-withdrawing group with a Van der Waals radius of 1.35 Å, only slightly larger than that of hydrogen (1.2 Å); second, fluorine atom is the most electronegative element, presenting a Pauling electronegativity of 4.0, which is much larger than that of hydrogen (2.2).(127) In addition, fluorine atoms often have a great effect on interand intramolecular interactions via C-F•••H, F•••S, and C-F•••πF interactions.(274, 276) Such interactions can improve molecular organization leading to shorter π-π stacking distances that improve charge carrier mobility.(277) Fluorination may be therefore a promising strategy to improve the PCE of OPV devices. To theoretically study the effect of fluorine substitution, we started from the simple case: the fluorinated diTBz derivative, 5,6-difluoro-4,7-dithieno-2,1,3-benzothiadiazole (diTffBz), deriving from Figure II-10. To compare the calculated results on diTBz and diTffBz, their corresponding frontier orbitals and electronic properties with different conformations are provided in Figure II-17. Like it was the case for diTBz, it shows no difference in the electron density distribution among the three conformations of diTffBz. The HOMO is distributed over the whole molecule, while the LUMO is concentrated on the electron-accepting Bz unit. It

Figure II- 17 :

 17 Figure II-17: Frontier molecular orbitals and electronic properties of diTBz and diTffBz with different conformations calculated by DFT. (Eh = Hartree energy, 1 hartree = 27.2107 eV)Following calculation results on diTffBz, the fluorinated Bz(T1CAMe)2, Bz(T2CAMe)2, Bz(T3CAMe)2 and Bz(T4CAMe)2 are named as ffBz(T1CAMe)2, ffBz(T2CAMe)2, ffBz(T3CAMe)2 and ffBz(T4CAMe)2 with the diTffBz core. Their geometries at the ground state were optimized using DFT method with the B3LYP/Def2-TZVP(-f) level. Similarly, the structural analysis for optimized geometries of these fluorinated derivatives were investigated by examinating calculated dihedral angles (as indicated in Figure. These results are presented in Table

Figure II- 18

 18 Figure presents their frontier orbitals and electronic properties. The comparison of these results with those obtained with Bz(T1CAMe)2, Bz(T2CAMe)2, Bz(T3CAMe)2 and Bz(T4CAMe)2 shows that the fluorination reduces HOMO and LUMO energy levels simultaneously but widens the energy gap of about 0.1 eV. In addition, from Bz(T1CAMe)2 to Bz(T4CAMe)2, the HOMO and LUMO energy levels are increased simultaneously with the increase in the conjugation length, and the increasement in the degree of HOMO energy level is larger than that of LUMO energy level, leading to lowering tendency in the band gap. It also shows similar electron density distribution of the frontier orbitals: the HOMOs of ffBz(T1CAMe)2, ffBz(T2CAMe)2 and ffBz(T3CAMe)2 are distributed entirely over the conjugated backbone that adopts an aromatic character, and their LUMOs are rather localized on benzothiadiazole unit with a quinoid character; for ffBz(T4CAMe)2, its HOMO orbitals is more localized in the central part of the backbone, while its LUMO is more localized on the benzothiadiazole and cyano groups, which is related to its elongated chain.

Figure II- 18 :

 18 Figure II-18: Frontier molecular orbitals and electronic properties of ffBz(T1CAMe)2, ffBz(T2CAMe)2, ffBz(T3CAMe)2 and ffBz(T4CAMe)2 at B3LYP/Def2-TZVP(-f) level.

Figure II- 19 :

 19 Figure II-19: Simulated absorption spectra of Bz(T1CAMe)2, ffBz(T1CAMe)2, Bz(T2CAMe)2, ffBz(T2CAMe)2 at BHandHLYP/ Def2-TZVP(-f) level. III. 2 DTS-based small molecules A set of A-D-A-D-A-D-A-type molecules (DTS(BzT2CAO)2, DTS(TBzT1CAO)2 and DTS(TBzT2CAO)2) based on DTS core have been envisaged (see Scheme II-2). In order to facilitate the computation, all the octyl chains were replaced with methyl group, leading to molecules DTS(BzT2CAMe)2, DTS(TBzT1CAMe)2 and DTS(TBzT2CAMe)2, as displayed in Figure II-20. Similar calculations were conducted on molecules containing DTS. These molecules are much more complex than Bz-based molecules and thus the necessary calculations require long time to optimize the geometry. Whereas the vibration frequency calculations have not performed currently, we may estimate that the calculated structures are very close to those of the ground state. This allows us to have a clear vision of the influence of the conjugation length on the molecular structure.

Figure II- 20 :

 20 Figure II-20: The scheme of dihedral angles for structural analysis. The structural analysis for optimized geometries of DTS(BzT2CAMe)2 and DTS(TBzT1CAMe)2 (Note that the geometry optimization of DTS(TBzT2CAMe)2 has not accomplished yet) were studied by examining calculated dihedral angles (defined as the dihedral angle for adjacent rings) indicated in Figure II-20. These results are summarized in

  )2 and DTS(TBzT1CAMe)2 are presented in Figure II-21. One can observe that the electron spatial distributions of their HOMOs are more localized on the central part of the backbone, and their LUMOs are slightly localized on the benzothiadiazole core and the cyano group. Besides, the

Figure II- 21 :

 21 Figure II-21: Frontier molecular orbitals and electronic properties of DTS-based small molecules calculated by DFT at B3LYP/Def2-TZVP(-f) level.

Figure II- 22 :

 22 Figure II-22: Chemical structures of calculated SubPcs-based small molecules. A purely theoretical work has been completed on molecules derived from boron SubPcs. The frontier orbital and electronic properties of SubPcs-based small molecules are shown in Figure II-23. In general, one can observe that the designed axial substitution leads to reduction in energy levels of both frontier orbitals and results in lowering the energy gap of phenoxy-SubPcs. Substituent PBzT1CAMe shows greater effect on the LUMO energy level and band gap of phenoxy-SubPc than PBzT1CHO does. Similarly, PBzT2CAMe shows greater effect on the LUMO energy level and band gap of the phenoxy-SubPc than PBzT2CHO does. The slight energy difference between energy gaps of similar compounds, like SubPc-PBrBzT1CHO and SubPc-PBrBzT2CHO, SubPc-PBrBzT1CAMe and SubPc-PBrBzT2CAMe), are of 0.06 eV and 0.07 eV, respectively, which can be ignored. For phenoxy-SubPc, it shows that the electron density distribution of both HOMO and LUMO are only localized on the macrocycle of SubPcs, which is in accordance with the prediction of HOMO and LUMO energy levels of boron subphthalocyanines reported by Bender et al.(251)Interestingly, with regard to axial substituted SubPc derivatives, the electron density distribution of the HOMO is localized on the macrocycle of SubPcs for most of the derivatives, excluding SubPc-PBzT2CHO for which the HOMO is localized on the axial substituent. This unusual distribution of HOMO of SubPc-PBzT2CHO could be ascribed to the more electron-rich bithiophene fragment relative to macrocycle. This phenomenon is in accordance with the axial thiophene-BSubPcs reported byMauldin et al. (219) For SubPc-PBrBzT1CHO and SubPc-PBrBzT2CHO, their electron density distribution of the LUMO is greatly located on the axial substituents and slightly distributed on the macrocycle of SubPcs. This may due to the electron-rich nature of the thiophene or bithiophene fragments. It is worth to note that for SubPc-PBrBzT1CAMe and SubPc-PBrBzT2CAMe, the LUMOs are localized only on the axial substituents, which could be attributed to the electron-withdrawing nature of

Figure II- 23 :

 23 Figure II-23: Frontier molecular orbitals and electronic properties of SubPcs-based small molecules calculated by DFT at B3LYP/Def2-TZVP(-f) level.

Figure II- 24 :

 24 Figure II-24: Structure of axial substituents.The frontier molecular orbitals and electronic properties of the four substituents are provided in Figure One can observe that for similar fragments, like PBrBzT1CHO and PBrBzT2CHO, PBrBzT1CAMe and PBrBzT2CAMe, increasing thiophene rings lead to increasing the energy levels (especially the HOMO levels) of both frontier orbitals, and results in reducing the energy gap of around 0.2 eV. This is due to the enhanced conjugation length. Comparing PBrBzT1CHO with PBrBzT1CAMe, we can see that both HOMO and LUMO energy levels are reduced (especially the LUMO energy levels) when introducing

Figure II- 25 :

 25 Figure II-25: Frontier molecular orbitals and electronic properties of axial substituents calculated by DFT at B3LYP/Def2-TZVP(-f) level.

  3 eV in the Scharber model. Theoretically, on one hand, all of the Bz-, DTS-, and SubPcs-based molecules could be used as electron donor when using PCBM as acceptor. In particular, with regard to DTS-based target molecules, their HOMO and LUMO energy levels are very close to those of ideal donor materials, making them promising donors for OPV cells. On the other hand, only molecules Bz(T1CAMe)2 and ffBz(T1CAMe)2 could act as electron acceptors when using P3HT as the donor.

Figure II- 26 :

 26 Figure II-26: Energy level diagram of molecules calculated by DFT at B3LYP/Def2-TZVP(-f) level.

  photovoltaics are often based on alternating electron donor and electron acceptor (D-A) moieties that result in materials with a strong absorption. From the synthetic point of view, the drawback of this D-A strategy is related to the coupling methods required for connecting these cores, bridges, and terminal units. On the one hand, D-A molecules are often obtained by units coupling via polluting synthetic procedures using stannylated derivatives (279) or via reactions involving diboronic acid pinacol esters which belong to a class of expensive and low yield isolated intermediates.(280, 281) On the other hand, direct arylation (the coupling of transition-metal (palladium, Rhodium, Ruthenium) catalyzed aryl C-H bonds with aryl halides) proceeds via C-H bond activation without need of the preparation of organometallic compounds, allowing for promising and atom-economical alternative to traditional cross-coupling reactions for the formation of new C-C bonds.(181) This method becomes very commonly used nowadays for polymers synthesis and is identified as an eco-friendly synthetic procedure offering new opportunities for the production of green energy from more environmentally friendly materials.(282, 283) It has recently emerged as a simple and feasible method to synthesize conjugated materials from simple building blocks for use in organic electronics.(182, 284-287) It was proposed two decades ago in pioneering works of Ohta et al. on direct arylation of thiophenes with aryl halides via C-H bond functionalization using palladium catalysis which gave moderate yields at 150°C.(288) Doucet and co-workers demonstrated that direct arylation can be considered as an environmentally and economically attractive approach to yield highly selective 2 or 5arylated thiophenes employing low loading catalyst at 150°C.(289-295) Moreover, the direct arylation through ligand-free catalysis offers advantages: properly used, the catalysis may be faster (296) and due to reduced numbers of additives and reactants, the work-up is easier and thus costs are reduced. The proposed mechanism of this procedure involves the decomposition at 100°C of Pd(OAc)2 with formation of solvent-stabilized Pd(0)-colloids in a polar solvent.(297) This is very close to what happens in the Heck reaction where Pd(OAc)2can be used as catalyst on aryl iodides without additional ligand.(298) However, if the solvent is concentrated (296) or if the catalyst/substrate ratio is too high, the solvent-stabilized Pd(0)colloids show a tendency to agglomerate and form non active black palladium powder. To our knowledge, the direct arylation without ligand at low catalyst loading has been used only once for π-conjugated polymers synthesis, in particular the polycondensation reaction of 3,3′,4,4′tetramethylbithiophene with 2,7-dibromo-9,9-dioctylfluorene in the presence of 2 mol % of Pd(OAc)2.(299) In this case however, 30 mol % of PivOH was used. This method offers simpler, shorter and cheaper reaction pathways for intermediates and final materials synthesis, and generates less toxic waste in comparison to classic cross-coupling techniques. The motivation of the present work is to demonstrate an unsophisticated and easy preparation of organic semi-conducting small molecules with a structure based on alternating D-A fragments, in accordance to the theoretical study presented in Chapter II. As demonstrated in Chapter I, among D and A fragments, thiophene (D), benzothiadiazole (A) and cyanoacetate

be exclusively 5 -

 5 photovoltaic performances. (205) Among the Bz-based molecules presented before, we chose to synthesize Bz(T1CAO)2, Bz(T1CAEH)2, Bz(T2CAO)2 and Bz(T2CAEH)2 because they are achievable in two steps. Their precursors Bz(T1CHO)2 and Bz(T2CHO)2 can be obtained from commercially available reagents, such as diBrBz, TCHO and T2CHO.

Figure III- 1

 1 Figure III-1 shows the structures of molecules that have been achieved in only two steps. The first step consists in synthesis of intermediates 5,5'-(2,1,3-benzothiadiazole-4,7-diyl)bis-(2thiophenecarboxaldehyde) (molecule Bz(T1CHO)2), or 5',5'''-(2,1,3-benzothiadiazole-4,7diyl)bis-[(2,2'-bithiophene)-5-carboxaldehyde] (Bz(T1CHO)2) by coupling a benzothiadiazolering with a thiophene or bithiophene carboxaldehyde unit, respectively. The second step consists in the Knoevenagel condensation of Bz(T1CHO)2 or Bz(T2CHO)2, respectively, with 2-ethylhexyl-or octyl-cyanoacetate. It is showed here that the coupling method may have a dramatic impact on environmental and economical parameters of the synthetic method.

Figure III- 1 : 2 . 2 .

 122 Figure III-1: Chemical structures of the synthesized molecules.

  reaction of TCHO with other aryl bromides.(305, 306) Only monoarylated product (see experimental section) and homocoupling product of thiophene carboxaldehyde ( 1 H NMR spectrum shown in Figure A.5 in Annexes) were detected as side products. In order to check the stability of the reactants under the reaction conditions, both starting materials diBrBz and TCHO were engaged separately in the direct arylation conditions via Route c without any other reactant. After 24h at 150°C, each batch was treated as previously described. Analyses of the batch conducted with diBrBz revealed the absence of homocoupling by-products and any other degradation processes, and the total recovery of diBrBz. It demonstrates the outstanding stability of di-bromobenzothiadiazole that does not undergo undesirable reaction.

  (d) Target molecules obtained by Knoevenagel condensation Finally, the four target molecules, Bz(T1CAEH)2, Bz(T1CAO)2, Bz(T2CAEH)2 and Bz(T2CAO)2, were obtained via Route c followed by Knoenenagel condensation. The overall green metrics are presented in

  Scheme II-2 in Chapter II). To obtain such precursors, it is now necessary to synthesize relevant DTS fragments. Their chemical structures are presented in Figure

Figure III- 2 :III. 1 1 - 1

 2111 Figure III-2: Chemical structures of various fragments for DTS-based target molecules. III. 1 Synthesis of mono-substituted compounds and related BzT2CAO molecule

Figure III- 3 :

 3 Figure III-3: Products found in the crude product of Suzuki reaction for fragment BrBzT1CHO.

  Finally, the thiophene moiety was protonated instead of reacting with Bz, forming TCHO and killing the catalytic cycle.In order to optimize the reaction yield in decreasing risks of degradation of the 5-formyl-2thiopheneboronic acid pinacol ester before it reacts, we tried to add it drop wisely under heating at 83 °C and vigorous stirring. Whereas the obtained yield was poorly reproducible, we reached at best 30% yield. This result may support the hypothesis of different reaction kinetics of diBrBz and thiophene carboxaldehyde boronic derivatives, which renders the coupling conditions tricky.Direct arylation methods were thus implemented to synthesis BrBzT1CHO via Routes b and c, as illustrated in Scheme III-5. Route b was conducted in toluene for four times under different conditions with fixed amount of catalyst and base. We tried to change the ratio between diBrBz and TCHO, the loading of ligand, the amount of additive, and length of reaction time. More details about synthesis are presented in the experimental section (see TableV-2). The same by-products as previously were found in the crude sample: diBrBz, molecule Bz(T1CHO)2, BrBzT1CHO and TCHO. The reaction yield was evaluated from 1 H

III. 1 - 3 2 Scheme III- 9 :

 1329 Scheme III-8: Strategy to obtain non-symmetric molecule BzT2CAO.

using 2 .

 2 Scheme III-11: Second strategy for obtaining DTS(BzT2CHO)2. The next step (or final step) will carry out the Knoevenagel condensation on DTS(BzT2CHO)2, which will form another A-D-A-D-A-D-A small molecule (This last step has not been conducted due to the limited time and graduation schedule).

  H NMR analysis. Their normalized absorption spectra in dichloromethane are shown in Figure III-4. Our spectrum of SubPcBCl (red) is in very good accordance with that of Bender.(221) Both BSubPc derivatives share very similar absorption curve that is characteristic of BSubPc derivatives in general.(234) The main absorption bands for SubPcBCl and phenoxy-SubPc are observed at λmax 565 and 563 nm with distinct shoulders at 549 and 547 nm, respectively.

Figure III- 4 :

 4 Figure III-4: Normalized absorption spectra of SubPcBCl and phenoxy-SubPc in CH2Cl2 solution. According to the designed SubPcs derivatives and synthetic strategy via axial substitution (see Scheme II-6 in chapter II), the next step will be carried out on phenoxy-SubPc with fragment BrBzT1CHO or BrBzT2CHO (see Figure III-2) via direct arylation procedure to achieve the axial substituted target molecules. Although both phenoxy-SubPc and BrBzT1CHO (or

  Many efforts and energy were devoted to the syntheses of DTS-based target molecules, from syntheses of various DTS-based fragments to syntheses of mono-substituted fragments. The final coupling between these fragments were first attempted via direct arylation procedure, and then conducted via traditional Stille coupling. One more step needs to be done on compound DTS(BzT2CHO)2 using Knoevenagel condensation, to get one DTS-based target molecule DTS(BzT2CAO)2 (A-D-A-D-A-D-A). Although direct arylation procedure did not succeed for the syntheses of DTS-based target molecules so far, it is without any doubt a green approach.

Figure IV- 1 .

 1 It is noticeable that the nature of the alkyl chain (R = octyl or 2-ethylhexyl) does not affect the absorption spectrum. The large absorption band that peaks at 497 nm and 525 nm for Bz(T1CAR)2 and Bz(T2CAR)2, respectively, can be attributed to the intramolecular charge transfer (ICT) transition.(322) A higher energy transition occurs at 385 nm and 450 nm for Bz(T1CAR)2 and Bz(T2CAR)2, respectively. It should be noted that the increase of the number of thiophene units from one to two at both sides of the benzozothiadiazole core induces a red shift of 28 nm, as a result of the extension of the conjugation.

Figure IV- 1 :

 1 Figure IV-1: Absorption spectra of the four molecules under study in DCM solution with concentrations as indicated.

Figure IV- 3 :

 3 Figure IV-3: UV-vis absorption spectra of molecules Bz(T1CAMe)2 and ffBz(T1CAMe)2 under study in DCM solution and by DFT at BHandHLYP/Def2-TZVP level. (Exp. indicates experimental absorption; Cal. means calculated absorption) The fluorescence in dichloromethane solution was also measured to analyse the emission due to excitation at a wavelength corresponding to the principal absorption, as shown in Figure IV-4. One can observe that Stokes shifts for compounds Bz(T1CAR)2 and Bz(T2CAR)2 are of 70 nm (0.32 eV) and 80 nm (0.30 eV), respectively. The fluorescence spectra of Bz(T1CAR)2 present two principal peaks: a maximum at 567 nm and a large shoulder at 606 nm. The energy between this two neighbouring peaks is about 0.14 eV (1129 cm -1 ), which could correspond to the vibration energy of the C=C ring stretching.(323) This phenomenon indicates a fine (or rigid) structure of Bz(T1CAR)2. The fluorescence spectra of Bz(T2CAR)2 show only one dominant wide peak at 625 nm.

Figure IV- 4 :

 4 Figure IV-4: Emission spectra of the four molecules under study in DCM solution with concentrations as indicated.

Figure IV- 5 :

 5 Figure IV-5: Normalized absorption and excitation spectra of Bz(T1CAO)2 in dichloromethane (left) and of Bz(T2CAR)2 in DCM (right). Transitioning from solution to the solid state (thin films were prepared by spin coating from dichlorobenzene solutions in collaboration with Dr. Isabelle Séguy from LAAS), as shown in Figure IV-6. We observe that the absorption band of both Bz(T1CAO)2 and Bz(T1CAEH)2 exhibit two maxima of equivalent intensity centred at about 540 and 580 nm, respectively.The energy between this two adjacent peaks is about 0.16 eV (1290 cm -1 ) that corresponds to the vibration energy of the C=C ring stretching. We can also observe a shoulder at about 504 nm for both molecules. Both molecules in solid state exhibit broad and red-shifted optical absorption maxima (Δλ = 40-110 nm), along with the emergence of fine structure within the low energy band. Such features are ascribed to a more rigid and ordered structure in the solid state, which result in greater π-electron delocalization across the molecular backbone and increased intermolecular interactions.(132)

  Figure IV-7: UV-vis absorption spectra of Bz(T1CAEH)2 film spin coated from chlorobenzene solution at room temperatures and annealed as indicated. The film was sequentially annealed at increasing temperature for 20 minutes. Blends of both Bz(T1CAO)2 and Bz(T1CAEH)2 with P3HT in thin film (1:1 wt. ratio) were prepared by spin coating via collaboration with Dr. Isabelle Séguy from LAAS laboratory. The absorption analysis on pristine thin films and blend are presented in Figure IV-8. Pure P3HT in thin film shows a typical -* absorption band centred at approximately 550 nmwith well-resolved shoulders at 523, 555, and 605 nm, respectively. For blend P3HT:Bz(T1CAO)2 (1:1 wt.), a maximum absorption peaks at 533 nm with a shoulder at 582 nm. The spectrum of the P3HT:Bz(T1CAO)2 blend shows the behavior of pristine Bz(T1CAO)2 film with the shoulder at around 580 nm, while the shoulder of P3HT at 605 nm collapsed. Similarly, P3HT:Bz(T1CAEH)2 blend shows the behavior of pristine Bz(T1CAEH)2

Figure

  Figure IV-8: Normalized absorption spectra of pure P3HT, Bz(T1CAO)2 and Bz(T1CAEH)2 and 1:1 wt. blends in thin films.

FigureFigure IV- 10 :

 10 Figure IV-9: Cyclic voltammetry of Bz(T1CAO)2 in 0.1 M PF6TBA dichloromethane solution; Pt electrode; scan rate = 200 mV.s -1 .

  1, their electrochemical gaps are in good agreement with the optical gaps. The high molar extinction coefficient (beyond 5.1 x 10 4 M -1 cm -1 ) at the maximum absorption wavelength is attributed to the strong conjugation of the alternating D-A structure.The five molecules exhibit deep LUMO energies values: -4.20 eV, -4.05 eV and -3.94 eV for the symmetrical thiophene, bithiophene derivatives and non-symmetrical bithiophene derivative, respectively. They also show deep HOMO energies values: -6.4 eV, -6.0 eV and -6.24 eV for the symmetrical thiophene, bithiophene derivatives and non-symmetrical bithiophene derivative, respectively. To make the parallel with well-known materials for OPV, we may point out that these LUMO and HOMO energy values are of 0.6 eV, 0.7 eV and 0.4 eV, respectively, lower than those of P3HT (-3.55 eV and -5.45 eV, respectively), and very close to those of PC60BM (-4.37 eV and -6.45 eV, respectively), as depicted in Figure IV-11 that offers visual comparison. Thus, if thin films made of these molecules exhibit good electron mobility, then they would be good acceptors candidates according to the energy levels of their frontier orbitals. Besides, we can observe the trends in decreasing optical and electrochemical band gap in solution from Bz(T1CAR)2 to Bz(T2CAR)2. These trends are supported by DFT calculations, as indicated in Figure The calculated HOMO and LUMO energy levels are higher than those obtained from experimental condition, and the band gap is 0.2 eV larger than experimental result. This trivial difference reveals that our calculations are of good accuracy. In addition, one can see the trends in decreasing optical and electrochemical band gap in solution from non-symmetrical structure to symmetrical structures.

94 a

 94 Figure IV-11: Diagram of the energy levels for the investigated molecules, P3HT and PCBM, estimated via electrochemical measurements. (All values have been measured in our laboratory in the same experimental conditions; Calc. represents calculated result)

Figure

  Figure IV-12: Cyclic voltammogram of pristine P3HT, Bz(T1CAO)2, Bz(T1CAEH)2 films and blend P3HT:Bz(T1CAO)2 (1:1 wt.) and blend P3HT:Bz(T1CAEH)2 (1:1 wt.) in 0.1 M PF6TBA acetonitrile solution; Pt electrode; scan rate = 50 mV.s -1 .

  ) a minimum energy offset(ΔE, between the LUMO level of the donor material and the PCBM of approximately 0.3 eV has been demonstrated necessary to achieve efficient electron transfer from the LUMO of the donor to the LUMO of PCBM acceptor.[START_REF] Scharber | Design rules for donors in bulk-heterojunction solar cells-Towards 10% energy-conversion efficiency[END_REF][START_REF] Brédas | Charge-Transfer and Energy-Transfer Processes in π-Conjugated Oligomers and Polymers: A Molecular Picture[END_REF][START_REF] Koster | Bimolecular recombination in polymer/fullerene bulk heterojunction solar cells[END_REF] On one hand, according to energy level diagram shown in Figure molecules Bz(T2CAO)2, Bz(T2CAEH)2 and BzT2CAO can be good candidates used as donors with PCBM as the acceptor. We can also predict that the power conversion efficiency based on Scharber model associated to Bz(T2CAO)2 and Bz(T2CAEH)2 may reach an ideal efficiency of 9.00 %, as the red cross marked in Figure IV-13. The blend using BzT2CAO as donor and PCBM as acceptor in an OPV device may reach an ideal efficiency between 6.00% and 7.00%, according to the red dot marked in Figure IV-13. Despite achieving ideal efficiency requires an ideal morphology and sufficient charge transport, it confirms that Bz(T2CAR)2 and BzT2CAO are promising donors for OPV devices. On the other hand, the energy level diagram of Figure IV-11 also suggests that all the five compounds may have the potential of being used as acceptors when blended with P3HT.

Figure IV- 13 :

 13 Figure IV-13: Outline plot showing the evaluated energy-conversion efficiency (contour lines and colours) versus the band gap and LUMO level of the donor based on Scharber model. A schematic energy diagram of a donor/PCBM system with the band gap energy (Eg) and the energy offset (ΔE) is also given.(61) Red cross indicates the ideal efficiency of Bz(T2CAR)2 used as the donor with PCBM as the acceptor. Red point indicates the ideal efficiency of BzT2CAO used as the donor with PCBM as the acceptor.

Figure IV- 14 :

 14 Figure IV-14: TGA plot of studied molecules with a heating rate of 10 °C/min under N2 atmosphere.

Figure IV- 15 :

 15 Figure IV-15: DSC thermograms of the molecules upon third heating and cooling cycles, measured at 10°C/min under nitrogen atmosphere. SAXS patterns of Bz(T1CAO)2 at 150°C (Figure IV-16) contain a unique sharp small-angle peak, corresponding to a layer spacing of 35.3 Å, and a broad wide-angle scattering due to liquid-like lateral distances between segregated chains and mesogens. Besides the usual signal from molten chains, hch, located at about 4.7 Å, two further maxima are observed for the rigid parts around 3.6 (h) and 7.2 Å (2h + h), respectively attributed to local-range face-to-face stacking and to overlapping contributions from face-to-face piled dimer and side-by-side lateral distances. Molecular areas AMol close to 30 Å 2 result from the ratio of estimated molecular volume (1040 ± 40 Å 3 ,   1.15 g.cm -3 ) and layer spacing. These values substantially exceed the cross-section of stretched chains (23.3 Å 2 at 150°C), which explains that the layer thickness is noticeably below the length of the entirely stretched molecule conformation (ca. 40 Å).

Figure IV- 16 :

 16 Figure IV-16: SAXS pattern of Bz(T1CAO)2 at 150°C, in the sanidic type smectic A phase. SAXS shows that Bz(T1CAO)2 is crystalline in the pristine state (Figure A.8 left), melts around 135°C to a smectic A phase with local stacking of the rigid parts (sanidic type smectic A phase -Figure IV-17a) (330) and gives rise to crystalline polymorphism upon cooling (Figure A.8 right). Cold crystallization however appears on the second heating in DSC and confirms that these monotropic organizations revealed by DSC are metastable and thus not accessible to the more time-demanding SAXS experiments which only evidenced crystalline phases (see Figure A.8). On the other hand, the metastable monotropic phases could be observed by POM analysis. Bz(T1CAO)2 revealed a batonnet-like texture (331) (Figure IV-17a) within a narrow temperature range from 185 to 180°C, corresponding to the formation of the monotropic smectic A (SmA) phase.(331) Then, a fan-shaped texture typical of a SmA phase is observed after maintaining the temperature at a constant value of 170°C for 30 minutes (Figure IV-17b). On cooling, the DSC curve presents two further low energetic transitions at 135°C and 60°C (ΔH = 1.4 and 2.2 kJ mol -1 , respectively), the broken fanshaped POM texture of the upper phase suggesting a tilted smectic phase with in-plane order (Figure IV-17c).(331) Clearly, Bz(T1CAO)2 shows crystalline and ordered mesophases below the fluid SmA phase which may be helpful for morphology control and interesting for charge transfer.(332) The alkyls chains play a central role in the appearance of mesomorphism, but as depicted in Yongsheng Chen's work,(137, 333) they are also crucial for the photovoltaic performance, apart from having great impact on donor and acceptor mixtures as well as on the π-conjugation.

Figure IV- 17 :

 17 Figure IV-17: POM images of (a) the batonnet-like texture of Bz(T1CAO)2 at 183°C, (b) the SmA phase of Bz(T1CAO)2 at 170°C and (c) the smectic phase observed at 85°C.

125 1 H

 1 NMR (400 MHz, CDCl3) δ 10.02 (s, 2H), 8.29 (d, J = 4 Hz, 2H), 8.08 (s, 2H), 7.90 (d, J = 4 Hz, 2H); 1 H NMR (400 MHz, 6 d DMSO) δ 10.03 (s, 2H), 8.43 (s, 2H), 8.38 (d, J = 4 Hz, 2H), 8.17 (d, J = 4 Hz, 2H).

Figure

  Figure V-1: 1 H NMR spectrum of Bz(T1CHO)2 in CDCl3 (top) and 6 d DMSO (down).

1 H

 1 NMR (400 MHz, CDCl3) δ 9.92 (s, 2H), 8.12 (d, J = 4 Hz, 2H), 7.96 (s, 2H), 7.74 (d, J = 4 Hz, 2H), 7.50 (d, J = 4 Hz, 2H), 7.41 (d, J = 4 Hz, 2H); 1 H NMR (400 MHz, 6 d DMSO) δ 9.90 (s, 2H), 8.32 (s, 2H), 8.03 (d, J = 4 Hz, 2H), 7.64 (d, J = 4 Hz, 2H), 7.52 (d, J = 4 Hz, 2H), 7.60 (d, J = 4 Hz, 2H).

Figure 2 :

 2 Figure V-2: 1 H NMR spectrum Bz(T1CHO)2 in CDCl3 (top) and 6 d DMSO (down).

1 H 2 :

 12 Figure V-3: 1 H NMR spectrum of Bz(T1CAO)2.

Figure 2 :

 2 Figure V-4: 1 H NMR spectrum of Bz(T1CAEH)2.

1

  HNMR (400MHz, CDCl3):  8.30 (s, 2H), 8.12 (d, J = 4 Hz, 2H), 7.97 (s, 2H), 7.72 (d, J = 4 Hz, 2H), 7.53 (d, J = 4 Hz, 2H), 7.40 (d, J = 4 Hz, 2H), 4.33 (t, J = 6.8 Hz, 4H), 1.78 (m, 4H), 1.35 (m, 20H), 0.92 (m, 6H). MS (CI-NH3): [M] + calcd for C46H46N4O4S5: 878.2; found: 879.6. Element. Anal. Calcd for C46H46N4O4S5: C, 62.84; H, 5.27; N, 6.37; found: C, 62.59; H, 5.04; N, 6.60. UV-vis (CH2Cl2): λmax = 522nm; ε = 53440 L•mol -1 •cm -1 ; Optical Gap = 2.0 eV (λonset = 630nm).

Figure 2 :

 2 Figure V-5: 1 H NMR spectrum of Bz(T2CAO)2.

1

  HNMR (400MHz, CDCl3): 8.30 (s, 2H), 8.12 (d, J = 4 Hz, 2H), 7.97 (s, 2H), 7.73 (d, J = 4 Hz, 2H), 7.53 (d, J = 4 Hz, 2H), 7.41 (d, J = 4 Hz, 2H), 4.25(t, J = 6.8 Hz, 4H), 1.74 (m, 4H),1.37 (m, 20H), 0.97 (m, 6H). MS (CI-NH3): [M] + calcd for C46H46N4O4S5: 878.2; found: 879.6. Element. Anal. Calcd for for C46H46N4O4S5: C,62.84; H, 5.27; N, 6.37; found: C, 63.10; H, 5.53; N, 6.34. UV-vis (CH2Cl2): λmax = 525nm; ε = 53440 L•mol -1 •cm -1 ; Optical Gap = 2.0 eV (λonset = 632nm).

Figure

  Figure V-6: 1 H NMR spectrum of Bz(T2CAEH)2.

1 H

 1 NMR (400 MHz, CDCl3): δ 10.01 (s, 1H), 8.21 (d, J = 4.0 Hz, 1H), 7.95 (d, J = 7.6 Hz, 1H), 7.88 (d, J= 7.6 Hz, 1H), 7.87 (d, J= 4 Hz 1H).

1

  HNMR (400 MHz, CDCl3): δ 9.92 (s, 1H), 8.07(d, J = 4 Hz, 1H), 7.91(d, J = 7.6 Hz, 1H), 7.78(d, J = 7.6 Hz, 1H), 7.74 (d, J = 4 Hz, 1H), 7.47 (d, J = 4 Hz, 1H), 7.39 (d, J = 4 Hz, 1H).

1 H

 1 NMR (400 MHz, CDCl3): δ 9.91 (s, 1H), 8.09 (d, J = 4.0 Hz, 1H), 8.00 (dd, J = 8.8, 0.9 Hz, 1H), 7.92 (dd, J = 7.1, 0.9 Hz, 1H), 7.74 (d, J = 4.0 Hz, 1H), 7.68 (dd, J = 8.8, 7.1 Hz, 1H), 7.48 (d, J = 4.0 Hz, 1H), 7.39 (d, J = 4.0 Hz, 1H)

Figure

  Figure V-7: 1 HNMR spectrum of BzT2CAO.

  1 HNMR (400MHz, CDCl3): δ (ppm) = 8.87-8.77 (6H, m), 7.94-7.89 (6H, m), 6.77 (t, J = 7.6 Hz, 2H),6.63 (t, J = 7.6 Hz,1H), 5.40 (d, J = 7.6 Hz, 2H).

Figure

  Figure V-8: 1 HNMR spectrum of phenoxy-SubPc 2-(2,2-dicyanovinyl)thiophene(34)2-thiophenecarboxaldehyde (654 mg, 5.4 mmol), malononitrile (705mg, 8.8 mmol), and basic aluminum oxide (2.55g) were stirred in dry toluene(50 mL) for 11 h at 70°C. After cooling down to room temperature, the reaction solution was diluted with toluene and filtered through a pad of silica gel. After removal of solvent, the residue was purified by recrystallization from ethanol to yield yellow crystals in 88% yield (760 mg).1 H NMR (400 MHz, CDCl3): δ 7.90 (dd, J = 5.5, 1.5 Hz, 2H), 7.83 (d, J = 3.9 Hz, 1H), 7.31 -7.29 (m, 1H).2-[2-[5'-(7-bromo-2,1,3-benzothiadiazole-4-yl)]thienylmethylene]-propanedinitrile.2-(2-thienylmethylene)-propanedinitrile (1 g, 6.21 mmol), 4,7dibromobenzo-2,1,3-thiadiazole (555 mg, 1.89 mmol), potassium acetate (613 mg, 6.26 mmol), and PdCl(dppb) (36 mg, 0.070 mmol) were dissolved in cyclopentyl methyl ether (CPME) under argon atmosphere in a three-necked flask. The reaction mixture was stirred at 103°C for 28 h. After cooling down to room temperature, the solvent was evaporated under vacuum, and the residue was subjected to flash chromatography on silica gel using ethyl acetate and petroleum ether (1:4) three times to afford 18 mg orange solid (3% yield). 1 H NMR (400 MHz, CDCl3) δ 8.26 (d, J = 4.0 Hz, 1H), 7.96 (d, J = 7.6 Hz, 1H), 7.91 (d, J = 7.6 Hz, 1H), 7.88 (s, 1H) 7.87 (d, J = 4.0 Hz, 1H).

  To a solution of 3,3'-dibromo-5,5'-bis(trimethylsilyl)-2,2'-bithiophene(1.98 g, 4.23 mmol) in dry THF(40 mL) was added a 2.5 M solution of n-butyllithium in hexanes(3.6 mL, 8.88 mmol) drop wisely at -78°C. After stirring at -78 °C for 15 min, di-n-chlorodioctylsilane (1.8 mL, 5.08 mmol) was introduced in one portion by syringe to the solution, and then the cooling bath was removed to warm the mixture to room temperature. After stirring for 2 h under room temperature, the mixture was poured into water and extracted with diethyl ether for several times. After removal of the solvent, the residue was purified by flash chromatography on silica gel using hexane as eluent to give yellow oil in 53% yield (1.24 g).1 H NMR (400 MHz, CDCl3) δ 7.18 (s, 2H),1.50 -1.40 (m, 4H), 1.34 -1.20 (m, 20H), 1.0 -0.9 (m, 10H), 0.39 d]silole (1.24 g, 2.2 mmol) in THF (15 mL). After being stirred at ambient temperature for 4.5 h, the mixture was extracted with diethyl ether, and the volatiles were evaporated under vacuum. The residue was subjected to flash chromatography on silica gel using hexane as eluent to give light yellow oil (702 mg, 56% yield).1 H NMR (400 MHz, CDCl3) δ 7.05 (s, 2H),1.40 -1.28 (m, 28H), 0.94 (m, 6H).

  mL dry THF and cooled down to -78°C by a liquid nitrogen-acetone bath. Then nbutyllithium solution in hexanes (2.5 M)(3.5 mL, 8.64 mmol) was added drop by drop in 10 mins. The reaction mixture was stirred for 15 mins at -78°C, di-n-chlorosilane(1.5 mL, 4.32 mmol) was added in one portion, then the cooling bath was removed and the solution was stirred overnight. Then the solution was poured into water and extracted with diethyl ether for several times. The organic phase was dried over anhydrous MgSO4. After removal of the solvent, the residue was purified by flash chromatography on silica gel using hexane as eluent to yield light yellow oil (24 mg, 1%).1 H NMR (400 MHz, CDCl3) δ 7.22 (d, J = 4.4 Hz, 1H), 7.10 (d, J = 4.8 Hz, 1H), 1.47 (m, 4H), 1.30 (m, 20H), 0.93 (m, 10H). mmol) was dissolved in 5 mL dry toluene and degassed under argon for a while. Then the 5 mL solution was introduced to the flask by syringe in one portion, then 95 mL dry toluene was added in one porting. After, tetrakis(triphenylphosphine) (Pd(PPh3)4) (2.2 mol % relative to 2-(tributylstannyl)) was added and the mixture was refluxed for 15 h. After cooling down to room temperature, the reaction mixture was poured into water and extracted with diethyl ether. After removal of the solvent, the residue was purified by column chromatography on silica gel using hexane as eluent to give red oil (400 mg, 56%).1 H NMR (400 MHz, CDCl3) δ 7.21 (dd, J = 5

Fragment

  49 mmol) in dry toluene(12 mL) was degassed with argon for 25mins, following the addition of Pd(PPh3)4 (14 mg, 0.012 mmol). After stirring and refluxing for 24 h at 110 °C with the protection of argon, the reaction mixture was poured into water (10 mL) and extracted with CH2Cl2 (10 mL x 2). The organic layer dried over anhydrous Na2SO4. After removal of solvent, the crude product was purified by silica gel using ethyl acetate:petroleum ether (1:4 to 1:1 to 1:0) as eluent to afford compound DTS(BzT2CHO)2. 1 H NMR (400 MHz, CDCl3) δ 9.92 (s, 1H), 8.23 (s, 2H), 8.09 (d, J = 4.0 Hz, 1H), 7.94 (d, J = 1.0 Hz, 1H), 7.74 (d, J = 4.0 Hz, 1H), 7.49 (d, J = 3.8 Hz, 1H), 7.40 (d, J = 4.0 Hz, 1H), 1.42 -1.34 (m, 4H), 1.32 - 1.20 (m, 20H), 1.09 (m, 4H), 0.89 -0.80 (m, 6H).

Figure A. 2 :Figure

 2 Figure A.2: Catalytic cycle of Suzuki-Miyaura cross-coupling reaction.

Figure A. 4 : 5 Figure A. 5 : 1 H

 4551 Figure A.4: Catalytic cycle of direct arylation between a thiophene and bromobenzene using a carboxylate additive.(182)

Figure

  Figure A7-I: SOMO of the oxidized form of Bz(T2CAMe)2.

Figure A7 - 2 Figure

 A72 Figure A7-III: Simulated absorption spectrum of Bz(T1CAMe)2 in CH2Cl2 and Natural transitions orbital isodensity surface for main transitions (f>0.05) of Bz(T1CAMe)2

Figure I- 1 : 5 Figure I- 2 : 6 Figure I- 3 : 6 Figure I- 4 :Figure I- 5 : 11 Figure I- 9 : 12 Figure I- 10 : 14 Figure I- 11 : 15 Figure I- 12 : 15 Figure I- 13 : 16 Figure I- 14 : 18 Figure I- 15 : 20 Figure I- 16 : 25 Figure I- 19 : 26 Figure I- 20 :

 15263645119121014111512151316141815201625192620 Figure I-1: World total primary energy supply in 2013, provided by International Energy Agency. Coal: peat and oil shale are aggregated with coal, other: geothermal, solar, wind, heat, etc., are included.(7) .......................................................................................................... 5 Figure I-2: U.S. energy consumption by energy source in 2014. Source: U.S. Energy Information Administration.(11) ................................................................................................ 6 Figure I-3: The spectrum of solar radiation.(12) ........................................................................ 6 Figure I-4: Device architecture of a bulk heterojunction photovoltaic cell. .............................. 7 Figure I-5: Number of publications dealing with organic solar cells during the period of 1980-2016 (Source Scopus). ................................................................................................................ 7 Figure I-6: The latest chart on record cell efficiencies, provided by The National Center for Photovoltaics (NCPV) at National Renewable Energy Laboratory (NREL).(33) Progress in photovoltaic power conversion efficiencies is tracked six monthly by Green et al.(34) ........... 8 Figure I-7: Basic energy level diagram and illustration of energy gap in molecular case of an organic semiconductor.(53) ...................................................................................................... 10 Figure I-8: Functional principle of a D/A solar cell. ................................................................ 11 Figure I-9: Absorption coefficients of films of commonly used materials are depicted in comparison with the standard AM 1.5 terrestrial solar spectrum (up)(according to Ref.(56)), and the structures of the materials (down). .............................................................................. 12 Figure I-10: Standard Solar Spectra for space and terrestrial use. (Source: pveducation) ....... 14 Figure I-11: Scheme of the sunlight path length, in units of Air Mass and dependent on the angle from the vertical (zenith angle θ). (Source: pveducation) .............................................. 15 Figure I-12: Current density versus voltage schematic diagram of organic solar cells in the dark and under illumination. .................................................................................................... 15 Figure I-13: Schematic energy level diagram between an ideal polymer and a PC61BM acceptor.(63) ............................................................................................................................. 16 Figure I-14: Efficiency of a D/A OPV cell vs the band gap energy of the donor, and the LUMO offset between the two materials.(79) ......................................................................... 18 Figure I-15: The architecture structure of (a) bilayer heterojunction and (b) BHJ OPV devices.(84) .............................................................................................................................. 20 Figure I-16: Schematic energy level diagram of an OPV, revealing the anode and cathode work functions, the HOMO and LUMO offsets (ΔHOMO and ΔLUMO, respectively) and the maximum open-circuit voltage (Voc).(87) ................................................................................ 21 Figure I-17: Schematic architecture of an organic tandem solar cell including two sub-cells with different and complementary absorption spectra.(79)...................................................... 23 Figure I-18: trans-polyacetylene and its schematic π orbital. .................................................. 25

Figure I- 25 : 35 Figure I- 27 : 37 Figure II- 1 : 46 Figure II- 2 : 46 Figure II- 3 : 48 Figure II- 5 : 50 Figure II- 6 : 52 Figure 57 Figure 58 Figure II- 9 : 61 Figure II- 12 : 62 Figure II- 13 : 63 Figure II- 14 : 64 Figure II- 15 : 65 Figure II- 16 : 66 Figure II- 17 : 68 Figure II- 18 : 70 Figure II- 20 : 71 Figure II- 21 : 72 Figure II- 22 : 73 Figure II- 23 : 74 Figure II- 24 : 74 Figure II- 25 : 76 Figure III- 1 : 82 Figure III- 2 : 89 Figure III- 3 : 90 Figure III- 4 : 99 Figure IV- 1 :Figure IV- 4 :Figure IV- 5 :Figure IV- 6 :

 25352737146246348550652575896112621363146415651666176818702071217222732374247425761822893904991456 Figure I-25: Chemical structures of representative small molecular-based donors. ................ 33 Figure I-26: Common fullerene and its derivatives acceptor materials. .................................. 35 Figure I-27: Chemical structures of fullerene-free acceptors for OPVs. ................................. 37 Figure II-1: The 26 building blocks (including chemical connections indicated by 'X') of the resulting CEP molecular candidate library. Five most efficient moieties in the top PCE are highlighted in green, and red indicates the five less efficient moieties.(188) .......................... 46 Figure II-2: Ranking of building blocks related to calculated PCE ≥ 10%.(188) .................... 46 Figure II-3: Chemical structures of some top candidates gathered in the CEPDB. ................. 47 Figure II-4: Pentacene-C60 bilayer interface simulated by molecular dynamics...................... 48 Figure II-5: Chemical structures of designed small molecules based on Bz core. ................... 50 Figure II-6: Chemical structures of some donor materials based on DTS core (C8 = octyl). .. 52 Figure II-7: 3D structure of SubPcBCl illustrating its unique bowl-shaped structure: a top view (left) and side view (right). (white sticks: H; grey sticks:C; blue sticks: N; yellow sticks: B; green stick: Cl).(221) ........................................................................................................... 57 Figure II-8: The axial and peripheral positions on SubPcBCl. (white sticks: H; grey sticks:C; blue sticks: N; yellow sticks: B; green sticks: Cl).(221) .......................................................... 58 Figure II-9: Chemical structures of some materials associated with SubPcs in OPV application. ............................................................................................................................... 59 Figure II-10: Conformations of diTBz characterized by dihedral angles (θA and θB). ............ 61 Figure II-11: Frontier molecular orbitals of diTBz in different conformations at the B3LYP/Def2-TZVP(-f) level. .................................................................................................. 61

Figure V- 7 : 1

 71 Figure V-7: 1 HNMR spectrum of BzT2CAO. ........................................................................

Figure V- 8 : 1

 81 Figure V-8: 1 HNMR spectrum of phenoxy-SubPc ................................................................

  photon et génération d'un exciton (paire électron-trou); (ii) diffusion de l'exciton à l'interface D/A; (iii) dissociation de l'exciton en porteurs de charge libres (électrons et trous), et (iv) transport et collecte des charges aux électrodes, générant un courant électrique dans le circuit externe. Chacune des quatre étapes intervenant de façon cruciale dans le processus global, il convient de les optimiser par le choix de matériaux D et A stables qui devront participer de façon la plus active possible à l'absorption de la lumière, posséder des niveaux d'énergie en faveur de la dissociation des charges, s'organiser en film mince de façon à favoriser le transport des charges et transférer aux électrodes les charges générées.

Figure 1 :

 1 Figure 1: Principe de fonctionnement d'une cellule organique à hétérojonction donneur/accepteur.

Figure 2 :

 2 Figure 2: Courbes I(V) dans le noir et sous illumination d'une cellule OPV.

Figure 3 :

 3 Figure 3: Structures chimiques de polymères (gauche), et petites molécules (droite) donneurs d'électrons et de dérivés du fullerène (bas) et PCE associés.

Figure 4 :

 4 Figure 4: Structures chimiques de matériaux accepteurs d'électrons non-fullerène (gauche) et de dérivés du fullerène (droite) et PCE associés.

Figure 5 :

 5 Figure 5: Evolution comparée depuis 2003 des performances des cellules OPV respectivement à base de matériaux polymères et de petites molécules, utilisés comme donneurs d'électrons.[START_REF] Kan | A Series of Simple Oligomer-like Small Molecules Based on Oligothiophenes for Solution-Processed Solar Cells with High Efficiency[END_REF][START_REF] Zhao | Efficient organic solar cells processed from hydrocarbon solvents[END_REF][START_REF] Chen | High Performance Photovoltaic Applications Using Solution-Processed Small Molecules[END_REF][START_REF] Liu | Aggregation and morphology control enables multiple cases of high-efficiency polymer solar cells[END_REF]156)

Brédas ( 194 )

 194 ont étudié en détail les interactions entre le fullerène (C60) et le pentacène par modélisation en dynamique moléculaire. Les résultats obtenus décrivent la complexité morphologique à l'interface de la couche active qui affectera le processus électronique au cours de l'effet photovoltaïque. D'autre part, des simulations de morphologie réalisées à l'aide du modèle de Monte Carlo ont prédit l'importance de la qualité de la morphologie d'un mélange donneur-accepteur sur les performances de cellules de type BHJ(198).Tous ces travaux théoriques nous donnent des pistes pour la conception des molécules futures, aussi bien du point de vue moléculaire, grâce à des descriptions structurales moléculaires avancées, que du point de vue du matériau avec des descriptions théoriques des interfaces et des morphologies de plus en plus fines. Pour notre part, sur la base d'une synthèse bibliographique (partie II.5-4 du chapitre I), nous proposons ici des nouvelles structures moléculaires que nous avons soumises à des calculs théoriques dans le but d'anticiper les niveaux d'énergie de leurs orbitales frontières (HOMO et LUMO) et de valider leur utilité potentielle en OPV. Cette validation obtenue, nous pourrons alors envisager de les synthétiser. Ces dernières années, de nombreux efforts ont été consacrés à la conception et à la synthèse de petites molécules ou polymères à faible largeur de bande interdite et conçus selon une alternance de fragments donneur et accepteur (D/A). Nous avons suivi cette stratégie afin d'obtenir des matériaux absorbant fortement dans la région visible et proche infrarouge du spectre solaire.(199-201) Pour des raisons de facilité synthétique, nous avons ciblé des petites molécules symétriques dont la synthèse comporte peu d'étapes intermédiaires, 2 à 3 étapes s'avérant être un minimum. Les calculs, effectués avec le programme OCRA (183) utilisant la théorie fonctionnelle de densité (DFT) (184), ont pour but principal d'évaluer les niveaux d'énergie des orbitales frontières (HOMO et LUMO)de ces molécules cibles. Ils ont été conduits sur une série de petites molécules à base de benzothiadiazole (Bz),de 4,4'-di-n-octyl-dithiényl[3,2-b:2',3'-d]silane (ou dithiénylsilane, DTS) et de subphthalocyanines (SubPcs). Les molécules étudiées (voir Figure 6) ici sont de trois types, leurs structures ainsi que les voies de synthèses envisagées sont présentées: -Centrées sur le fragment benzothiadiazole, avec structures symétriques simples de type A-D-A-D-A. -Centrées sur le fragment dithiénylsilane (DTS), ce dernier étant un donneur d'électron reconnu pour sa stabilité chimique et fréquemment utilisé dans les matériaux efficaces en OPV (206-209,144). Nous avons proposé les structures de type A-D-A-D-A-D-A, plus étendues que les précédentes. -A base de subphtalocyanine (SubPc), qui se sont révélé être de bons matériaux donneurs (252-255) ou accepteurs (256) d'électrons pour des applications en OPV (216,218).

Figure 6 :

 6 Figure 6: Structures molécules à base de benzothiadiazole (gauche), de dithiénylsilane (haut droite) et de subphtalocyanine (bas droite).

Figure 8 :Tableau 3 :

 83 Figure 8: Structure des substituants axiaux de la chloro-subphtalocyanines de bore

Figure 9 :Schéma 1 :

 91 Figure 9: Diagramme d'énergie des orbitales frontières des molécules cible.

Schéma 3 :Schéma 4 :

 34 Synthèse du phenoxy-SubPc à partir du la SubPcBCl. Ce travail préliminaire, nécessaire à l'acquisition du savoir-faire dans la synthèse des dérivés de subphtalocyanines, sera poursuivi au laboratoire dans le futur. Pour cela, il est envisagé d'utiliser un phénol substitué en position para-par un fragment très proche de ceux vus précédemment, puis de le faire réagir sur la SubPcBCl pour obtenir les molécules cibles présentées en Figure 8. Le schéma réactionnel global est le suivant: Dérivés SubPcs cibles et stratégies de synthèse par substitution axiale. CHAPITRE IV : CARACTERISATION DES MATERIAUX Dans cette section, les composés Bz(T1CAO)2, Bz(T1CAEH)2, Bz(T2CAO)2, Bz(T2CAEH)2 et BzT2CAO sont étudiés en termes de propriétés optiques, électrochimiques, et thermiques afin d'évaluer leur potentielle utilisation en application photovoltaïque organique. Les composés symétriques montrent, pour une longueur de conjugaison équivalente, des spectres d'absorption et d'émissions similaires : la nature des chaines alkyle n'est pas un facteur influant sur leurs propriétés optiques. L'addition d'un noyau thiophène dans le chemin de conjugaison moléculaire provoque un effet bathochrome sur le spectre d'absorption électronique.

Figure 10 :

 10 Figure 10: Spectre d'absorption (à gauche) et d'émission (à droite) des molécules symétriques à base de Bz.

Figure 12 :

 12 Figure 12: Thermogrammes des molécules symétriques enregistrés au troisième cycle de chauffage à 10°C/min sous atmosphère d'azote.

Table I

 I

	-1, it is clear that PPV-based BHJ
	devices exhibit relatively poor performance, such as 2.3% and 2.5%. PCE as high as 3.3%
	was achieved in BHJ device based on MDMO-PPV which was blended with PC60BM as
	acceptor, attributed to active layer morphologies tune.(138, 139) Hereafter, P3HT-based BHJ
	devices have been thoroughly studied due to its lower band gap (1.9 eV) (as shown in Table I-
	1) which leads to a remarkably higher current density of more than 10 mA/cm 2 , as well as its
	enhanced π-stacking and crystallinity which results in a higher hole mobility.(140-142) An

impressive efficiency of 5% in BHJ device based on P3HT:PCBM blend was achieved by

Kim et al. in 2006 by optimizing active layer morphology.(141)

Table I -1: Electronic properties and OPV performance of some typical polymer-based donors.

 I

	restricts the device performance. Thus, presently, numerous novel conjugated polymers built
	from donor and acceptor building blocks have been emerged and have promoted a rapid
	development of high performance BHJ devices, such as poly[(4,4′-bis(2-
	ethylhexyl)dithieno[3,2-b:2′,3′-d]silole)-2,6-diyl-alt-(2,1,3-benzothiadiazole)-4,7-diyl]
	Donor	HOMO/LUMO a (eV)	Eg (eV)	Acceptor b	Jsc (mA cm -2 )	Voc (V)	FF	PCE (%)	Ref.
	MEH-PPV	-5.0/-2.8	2.2	PCBM	3	0.67	0.36	2.3	(143)
	MDMO-PPV	-5.3/-3.0	2.3	PC71BM	5.25	0.82	0.61	2.5	(138)
	P3HT	-5.2/-3.3	1.9	PCBM	11.1	0.61	0.66	5.0	(141)
	PSBTBT	-5.05/-3.27	1.78	PC71BM	12.7	0.68	0.55	4.75	(144)
	PCPDTBT	-4.9/-3.5	1.4	PC71BM	16.2	0.62	0.55	5.5	(48)
	PCDTBT	-5.5/-3.6	1.9	PC71BM	12.40	0.88	0.68	7.5	(28, 145)
	PBDT-DTNT	-5.19/-3.26	1.93	PC71BM	17.4	0.75	0.61	8.4	(146)
	PNT4T-2OD	-5.24/-3.71	1.53	PC71BM	19.8	0.76	0.68	10.1	(94)
	PBTff4T-2OD	-5.20/-3.57	1.63	PC71BM	18.2	0.77	0.74	10.4	(94)
	PTB7-Th	-5.22/-3.63	1.59	PC71BM	17.43	0.825 0.74	10.6	(96)
	PffBT4T-2OD	-5.34/-3.69	1.65	TC71BM	18.8	0.77	0.75	10.8	(94)
	a from electrochemistry, b for the detailed donor/acceptor weight ratio in device, see the relevant
	references.

Table I -2: Electronic properties and OPV performance of some typical small molecular donors.

 I

	Donor	HOMO/LUMO a (eV)	Eg (eV)	Acceptor	Jsc (mA cm -2 )	Voc (V)	FF	PCE b (%)	Ref.
	DTS(PTTh2)2	-5.2/-3.6	1.6	PC71BM	14.4	0.78	0.593 6.7	(29)
	DR3TBDTT	-5.02/-3.27	1.75	PC71BM	13.17	0.93	0.663 8.12	(155)
	p-DTS(FBTTh2)2	-5.12/-3.34	1.78	PC71BM	14.74	0.773 0.724 8.24	(154)
	DRCN7T	-5.08/-3.44	1.64	PC71BM	14.87	0.91	0.69	9.3	(19)
	DR3TSBDT	-5.07/-3.30	1.77	PC71BM	14.61	0.92	0.74	9.95	(156)
	DRCN5T	-522/-3.41	1.81	PC71BM	15.88	0.92	0.69	10.08	(19)
	a from electrochemistry, b for the detailed donor/acceptor weight ratio in device, see the relevant
	references.
	Heeger and co-workers, giving PCEs of 6.7% and 8.24% respectively.(29, 154) A series of
	small molecules-based donor materials blended with PC71BM reported by Y. Chen et
	al.exhibit higher efficiencies above 9%, such as DRCN7T, DR3TSBDT, DRCN5T listed
	here.

Figure I-26: Common fullerene and its derivatives acceptor materials.

	and good interaction with donor materials to form nanoscale morphological network in
	organic photovoltaic devices.(134, 157, 158)
	Buckminster-fullerene (C60) has first proven to be an ideal acceptor with conjugated polymer
	MEH-PPV donor by Sariciftci and co-workers in 1992.(39) Later, Yu et al. introduced the
	BHJ architecture and replaced C60 with its derivative [6,6]-phenyl-C61-butyric acid methyl
	ester (PC61BM) as acceptor.(35) The efficiency of BHJ cells are able to be further improved
	by replacing PC60BM with [6,6]-phenyl-C71-butyric acid methyl ester (PC71BM) due to its
	stronger light absorption in the visible spectrum region than that of C60. Indene-C60 bisadduct
	(ICBA) is easier to synthesis in comparison to that of PCBM and shows better solubility than
	PCBM. Table I-3 gives relevant examples about the efficiencies of OPVs based on fullerene
	derivatives acceptors, which indicates the development of electron acceptors based on
	fullerene derivatives. For instance, the device made from P3HT and ICBA presented a Voc of , both 0.84V, a Jsc of 10.61(mA cm -2 ), a FF of 0.727, and a PCE of 6.48% (158), which is higher showing power conversion efficiency over 10%. The highest PCE for single-junction OPVs based on small molecule reported to date has reached to 10.10%.(19) Via careful and than that of P3HT/PCBM (5.0%) (141).
	interdisciplinary efforts in the design and synthesis of new small molecules based on D/A
	building blocks, together with morphology control and device optimization, it is believed that
	the performance of a single junction OPV based on small molecule will achieve 12% in the
	near future.
	(c) Fullerene and fullerene derivative acceptors
	As the rapid development of electron-donating materials including polymers and small
	molecules, efficiencies of BHJ devices based on donor/fullerene derivatives blends have
	achieved over 11%.(21, 23) Taking into account of the wide spread in the reported good
	performances in OPVs, so far, fullerene derivatives (see Figure I-26) are no doubt considered
	as the more successful candidates for acceptor in OPVs, which can be ascribed to their
	advantages, such as good electron mobility and large electron affinity, adequate band gaps,

Table I-3: Electronic properties and OPV performance of typical fullerene and its derivatives as acceptors.

	Acceptor	HOMO/LUMO a (eV)	Eg (eV)	Donor	Jsc(mA cm -2 )	Voc (V)	FF	PCE b (%)	Ref.
	C60	-6.1/-3.7	2.4	SubPcBCl	3.36	0.97	0.57	2.1	(74)
	PCBM	-6.1/-4.3	1.8	P3HT	11.1	0.61	0.66	5.0	(141)
	PC71BM	-5.8/-4.0	1.8	DRCN5T	15.88	0.92	0.69	10.08	(19)
	ICBA	-5.7/-3.74	1.96	P3HT	10.61	0.84	0.73	6.48	(158)

a from electrochemistry, b for the detailed donor/acceptor weight ratio in device, see the relevant references.

Table I -4: Electronic properties and OPV performance of some typical non-fullerene acceptors.

 I

	Acceptor	HOMO/LUMO a (eV)	Eg (eV)	Donor	Jsc(mA cm -2 )	Voc (V)	FF	PCE b (%)	Ref.
	S(TPA-DPP)	-5.26/-3.26	2.0	P3HT	2.68	1.18	0.379	1.20	(166)
	Cz-RH	-5.53/-3.50	2.03	P3HT	4.69	1.03	0.53	2.56	(43)
	Flu-RH	-5.58/-3.53	2.05	P3HT	5.70	1.03	0.52	3.08	(43)
	PPDIDTT	-5.5/-3.6	1.9	PBDTTT-C-T	8.55	0.752 0.515	3.45	(167)
	DTBTF	-5.68/-3.62	2.06	DR3TSBDT	7.42	1.15	0.45	3.84	(136)
	FBR	-5.70/-3.57	2.14	P3HT	7.95	0.82	0.63	4.11	(22)
	TPE-PDI4	-5.77/-3.72	2.05	PBDTT-F-TT	11.7	0.91	0.52	5.53	(168)
	N2200	-5.9/-4.3	1.6	PBDTTT-EF-T	13.0	0.794 0.556	5.73	(169)
	ITIC	-5.48/-3.83	1.65	PTB7-TH	14.21	0.81	0.591	6.80	(164)
	a from electrochemistry, b for the detailed donor/acceptor weight ratio in device, see the relevant
	references.

  State of the art syntheses often rely on traditional cross-coupling methods

	(Suzuki, Stille, Heck, etc.) for the formation of new C-C bonds. However, these traditional
	coupling methods exhibit drawbacks including the usage of an organometallic reagent that
	yields a stoichiometric amount of metal waste and is often toxic, expensive, difficult to
	handle, and require extra synthetic steps. Owing to disadvantages of typical coupling
	methods, direct arylation (the coupling of transition-metal (palladium, Rhodium, Ruthenium)
	catalyzed aryl C-H bonds with aryl halides) proceeds via C-H bond activation without need of
	the preparation of organometallic. It has emerged as a feasible alternative, allowing for
	promising and atom-economical method to classical cross coupling reactions for the
	formation of new C-C bonds.(181, 182) Therefore, direct arylation can be added to chemists'
	toolbox. It would be quite attractive to give rise to organic materials for OPV devices by using
	this strategy.

Chapter II: Molecular design Chapter II : Molecular design

	I Introduction
	As mentioned in Chapter I, novel appropriate materials need to be designed and synthesized
	Molecular design to develop the OPV technology for the future demand. One design method is the conventional
	(2) Green chemistry approach for materials synthesis experimental development of novel materials that is mainly based on experience or empirical
	(3) Materials characterization intuition with a certain series of molecules. Employing this method, one obvious drawback is
	that only a few materials per year can be studied by an experimental team owing to the
	lengthy and complicated synthesis and characterization procedures. The other design method
	is based on the virtual large-scale screening framework conducted by theoretical research and
	assessment using first-principles quantum chemistry. Here, it is worth mentioning that the
	Harvard Clean Energy Project has made great effort to molecules design; more details will be
	addressed below.
	I. 1

Theoretical work on molecular design

	The Harvard Clean Energy Project (CEP) initiated in 2008, is a theory-driven and high-
	throughput screening framework for the aim of identifying promising high-performance
	material candidates for organic electronics, in particular organic photovoltaics.(187-189) It is
	administered by the Alán Aspuru-Guzik Research Group at Harvard University and supported
	by many external contributors and collaborators.(190, 191) The CEP currently focuses on the
	characterization of millions of molecular motifs by means of first-principles quantum
	chemistry. In this project, millions of molecular structures were studied to propose proper
	compounds particularly for the harvesting and conversion of solar energy and for other
	organic electronic applications. To our knowledge, the CEP is the most extensive quantum
	chemical study ever conducted. The computational exploration of compounds merging the
	level of theory and scope established in the CEP is unprecedented. So far, 2.3 million
	molecular motifs derived from 150 million density functional theory (DFT) simulations and
	comprised 400TB of data have been assessed. These massive data are stored and freely
	accessible in the Clean Energy Project Database (CEPDB) which is a massive reference
	database for organic semiconducting materials with a special emphasis on organic
	photovoltaic applications.(192) The 2.3 million molecular motifs are based on 26 building

Table II -1: Electronic properties and OPV performance of some typical donors based on dithienosilole core.

 II

	Donor	HOMO/LUMO a (eV)	Eg (eV)	Acceptor	Jsc (mA cm -2 )	Voc (V)	FF	PCE b (%)	Ref.
	BDCDTS	-5.80/-3.92	1.88	C60	0.73	0.43	0.24	0.07	(210)
	BCNDTS	-5.40/-3.23	2.17	C60	4.17	1.02	0.54	2.3	(210)
	C8-Ester	-5.28/-3.52	1.76	PCBM	9.79	0.82	0.54	4.35	(205)
	DCAO3TSi	-4.95/-3.26	1.69	PCBM	11.51	0.80	0.64	5.84	(211)
	DTS(PTTh2)2	-5.2/-3.6	1.6	PC71BM	14.4	0.78	0.593 6.7	(29)
	p-DTS(FBTTh2)2	-5.12/-3.34	1.78	PC71BM	14.74	0.773	0.724 8.24	(154)

a from electrochemistry, b for the detailed donor/acceptor weight ratio in device, see the relevant references.

Table II -2: Performance of some OPV devices based on SubPcs.

 II

	Donor	Acceptor	Jsc (mA cm -2 )	Voc (V)	FF	PCE a (%)	Ref.
	SubPcBCl	C60	5.4	0.92	0.61	3.0	(216)
	SubPcBCl	FSubPcDimer	7.8	0.95	0.54	4.0	(226)
	α-6T	SubPcBCl	4.17	1.02	0.54	4.69	(31)
	α-6T	SubNcBCl/SubPcBCl	9.79	0.82	0.54	8.40	(31)

Table II -3: Total energy, orbital energy levels and dihedral angles of diTBz.

 II

	conformation	Total energy (Eh)	HOMO/LUMO (eV)	Eg (eV)	θA/θB (°)
	trans-trans -1842.65750205	-5.60/-2.85	2.75	2.17 / 5.21
	trans-cis	-1842.65638543	-5.64/-2.80	2.84	20.85 / 23.28
	cis-cis	-1842.65547381	-5.60/-2.80	2.80	22.18 / 18.89

Table II -

 II 4.

	Bz(T 1 CAMe) 2
	Bz(T 2 CAMe) 2
	Bz(T 3 CAMe) 2
	Bz(T 4 CAMe) 2

Table II -4: Dihedral angles (°) in Bz(T1CAMe)2, Bz(T2CAMe)2, Bz(T3CAMe)2 and Bz(T4CAMe)2.

 II

	θ A Frontier molecular orbitals of Bz(T1CAMe)2, Bz(T2CAMe)2, Bz(T3CAMe)2 and θ B Bz(T 1 CAMe) 2
	Bz(T4CAMe)2 are presented in Figure II-14. It illustrates that the HOMOs of Bz(T1CAMe)2
	Bz(T 2 CAMe) 2			θ A	θ B
	Bz(T 3 CAMe) 2
			θ C	θ A	θ B
	Bz(T 4 CAMe) 2
				θ A	θ B
		θA	θB	θC	θD	θE	θF	θG	θH
	Bz(T1CAMe)2	1.25	1.24
	Bz(T2CAMe)2	2.68	2.05	3.01	1.29
	Bz(T3CAMe)2	0.85	3.25	1.07	0.29	6.22	4.63
	Bz(T4CAMe)2	0.12	4.93	0.20	1.93	1.59	2.27	1.00	0.75

Table II -6: Dihedral angles (°) in ffBz(T1CAMe)2, ffBz(T2CAMe)2, ffBz(T3CAMe)2 and ffBz(T4CAMe)2.

 II

		Total Energy (Eh)		HOMO	LUMO		HOMO/LUMO (eV) E g (eV)
	diTBz (trans-trans) -1842.65750205					-5.60/-2.85	2.75
	diTBz (trans-cis)	-1842.65638543					-5.64/-2.80	2.84
	diTBz (cis-cis)	-1842.65547381					-5.60/-2.80	2.80
	diTffBz (trans-trans) -2041.20436988					-5.81/-2.95	2.86
	diTffBz (trans-cis)	-2041.20388083					-5.79/-2.94	2.85
	diTffBz (cis-cis)	-2041.20321912					-5.82/-2.91	2.91
		θA	θB	θC	θD	θE	θF	θG	θH
	ffBz(T1CAMe)2	3.81	0.95
	ffBz(T2CAMe)2	0.69	0.19	4.16	0.17
	ffBz(T3CAMe)2	3.65	8.85	1.70	1.90	4.63	3.07
	ffBz(T4CAMe)2 21.78	14.90	4.55	1.43	3.36	2.54	4.90	10.10

Table II -7: Dihedral angles (°) in DTS(BzT2CAMe)2 and DTS(TBzT1CAMe)2.

 II

		θA	θB	θC	θD	θE	θF	θG	θH
	DTS(BzT2CAMe)2	0.48	0.56	1.02	1.01	0.27	0.37
	DTS(TBzT1CAMe)2 4.43	4.36	0.26	0.60	7.00	1.42
	DTS(TBzT2CAMe)2	*	*	*	*	*	*	*	*

*Non-available data due to the time-consuming calculations.

  To provide a visual comparison, the HOMO and LUMO energy levels of molecules designed by DFT are presented in Figure The HOMO and LUMO levels of P3HT and PCBM were evaluated by cyclic voltammetry (CV) measurements in CH2Cl2 solution in our lab.

	HOMO	LUMO	HOMO/LUMO (eV)	Eg (eV)
	PBzT 1 CHO		-5.90/-3.08	2.82
	PBzT 2 CHO		-5.64/-3.04	2.60
	PBzT 1 CAMe		-5.95/-3.34	2.61
	PBzT 2 CAMe		-5.70/-3.27	2.43

Table III -1: Reaction yields, E-factors and costs calculated for Bz(T1CHO)2 obtained via the three investigated routes. Route a Route b Route c

 III

	Yield (%)	100%	98%	71%
	E-factor (g/g)	441	495	143
	Cost (€/g)	176	38.5	14
	Atom economy	41%	65%	47%

Table III -

 III 2. The reaction yield is improved, but with much worse green metrics. This is due to the fact that the non-reacted molecule diBrBz (when used in excess) is accounted as a waste, thus substantially contributes to the increase of the calculated value of the E-factor. Due to the fact that molecule diBrBz does not react by homocoupling reaction nor decomposes through any other degradation processes under these reaction conditions as demonstrated earlier, it may possible to recycle it. Thus, with optimized synthesis conditions, including the recycling of diBrBz, it is feasible to synthesize Bz(T1CHO)2 in 71% yield and more with an E-factor approaching 143 g/g and a cost of around 14 €/g as reported in first column of TableIII-2.

Table III -2: Reaction yields, E-factors and costs calculated for the synthesis of Bz(T1CHO)2 obtained via Route c with decreasing the TCHO/diBrBz ratios (r).

 III

		r = 2.2	r = 0.9	r = 0.5
	Yield (%)	71%	100%	100%
	E-factor (g/g)	143	226	408
	Cost (€/g)	14	22	39
		(c) Molecule Bz(T2CHO)2 obtained via Routes a and c

Table III -3: Reaction yields, E-factors and costs calculated for Bz(T2CHO)2 obtained via Route a and Route c.

 III

Table III -4: Reaction yields for Knoevenagel condensation, and total E-factors and costs calculated for the target molecules obtained via Route c followed by Knoevenagel condensation.

 III  In a general manner, the E-factor is twice higher for molecules bearing one thiophene ring at each side of benzothiadiazole, than for those bearing bithiophene units. This is directly linked to the E-factors for intermediate synthesis, of 143 and 76 g/g for compounds Bz(T1CHO)2 and Bz(T2CHO)2, respectively, and to the best Knoevenagel reaction yields obtained with molecule Bz(T2CHO)2.

		Bz(T1CAO)2	Bz(T1CAEH)2	Bz(T2CAO)2	Bz(T2CAEH)2
	Knoevenagel condensation yield	51%	47%	76%	68%
	Total E-factor (g/g) 230	380	144	162
	Total cost (€/g)	45	37	50	47

The estimated cost per gram is constant from one molecule to another, of around 45 €/g, which is acceptable for a fine chemical with a potential large scale application. It is worth noting that these numbers are maximum values deduced from (non-negotiated) prices of commercial raw materials, always more expensive at laboratory scale than for upscaling or industrial purpose.

Table IV -1: Optoelectronic properties of the target molecules.

 IV

		λmax	 (M -	Eg opt	Eox	Ered	Eg el	HOMO	LUMO
		(nm) a	1 cm -1 )	(eV) b	(V/Fc + /Fc) c	(V/Fc + /Fc) c	(eV) c	(eV) d	(eV) d
	Bz(T1CAO)2	498 51000	2.1	+1.01	-1.18	2.16	-6.4	-4.2
	Bz(T1CAEH)2 497 55000	2.1	+0.99	-1.17	2.19	-6.4	-4.2
	Bz(T2CAO)2	522 53440	2.0	+0.57	-1.34	1.91	-6.0	-4.05
	Bz(T2CAEH)2 525 53440	2.0	+0.55	-1.37	1.92	-5.9	-4.0
	BzT2CAO	461		2.36	+0.85	-1.45	2.30	-6.24	-3.

Table IV -2: Electronic properties of pristine P3HT, Bz(T1CAO)2, Bz(T1CAEH)2 films and blend P3HT:Bz(T1CAO)2 (1:1 wt.) and blend P3HT:Bz(T1CAEH)2 (1:1 wt.).

 IV

		Ered	Eox	Eg el	LUMO	HOMO
	Films
		(V/Fc + /Fc) a	(V/Fc + /Fc) a	(eV) a	(eV) b	(eV) b
	P3HT	-	0,06		-	-5.45
	Bz(T 1 CAO) 2	-1.16	+0.93	2.09	-4,23	-6.32
	Bz(T 1 CAEH) 2	-1.16	+1,03	2.19	-4,23	-6.42
	P3HT:Bz(T 1 CAO) 2 (1:1 wt.)	-1.16	+0,01	1.17	-4,23	-5.40
	P3HT:Bz(T 1 CAEH) 2 (1:1 wt.)	-1.19	+0,01	1.20	-4,20	-5.40

a Measured in CV in acetonitrile solution with FP6TBA electrolyte. b Estimated by cyclic voltammetry, with Fc/Fc + at 5.39 eV below vacuum.

Table V

 V

	-1 resumes the results obtained from various "r" molar ratios of 2-
	thiophenecarboxaldehyde/4,7-dibromobenzo-2,1,3-thiadiazole, and various amounts of
	palladium acetate (relative to 4,7-dibromobenzo-2,1,3-thiadiazole). The other parameters are
	fixed (quantity of 4,7-dibromobenzo-2,1,3-thiadiazole: 500 mg, KOAc: 334 mg, DMA: 6 mL,
	temperature of reaction: 150°C and time of reaction: 24 h)

Table V -1: Yields for molecule Bz(T1CHO)2 obtained from different Route c conditions.

 V

	r	palladium acetate Yield of reaction
	2.2	0.5%	71%
	0.9	0.5%	100%
	0.5	0.25%	100%

Table V -2: Yields for BrBzT1CHO obtained from different Route b conditions.

 V

	r	Ligand Additive Time (h) 1 H NMR Yield
	0.7	10%	30%	18	22%
	0.5	20%	1	6	5%
	1	20%	1	4	16%
	1	20%	1	4	10%

Table V -3: Yields for BrBzT1CHO obtained from different Route c (i) conditions.

 V

	T (°C)*	Time (h)	1 H NMR Yield
	105	21	16%
	115	2	20%
	125	1.75	16%
	140	24	0%

Table V -4: Yields for BrBzT1CHO obtained from different Route c (ii) conditions.

 V

	r	KOAc Pd(OAc)2	T (°C)*	Time (h)	Isolate Yield
	0.5	1.5	1%	105	21	35%
	0.7	2	0.5%	45	2	10%
	1	2	0.5%	45	1.75	10%
	1	2	0.5%	60	7	10%
	0.5	2	0.5%	105	24	trace
	1	2	0.5%	105	24	30%
	1	2	1%	105	24	trace
	1	2	1%	85	6	trace

Table V -5: Yields for SubPcBCl obtained from different conditions.

 V

	Treatment method Reaction time	Isolated yield
	i	3h	12%
	i	30min	6%
	ii	20min	7%
	i + ii	1.5h	34%
	ii	1h	47%
	1 HNMR (400MHz, CDCl3): δ (ppm) = 8.93 (6H, dd), 7.98 (6H, dd). 1 HNMR (400MHz,
	C6D6): δ (ppm) = 8.69 (6H, dd), 7.35 (6H, dd). 1 HNMR (400MHz, D6DMSO): δ (ppm) =
	8.92 (6H, dd), 8.08 (6H, dd).

Table A6 -

 A6 I: Molecule 5 obtained via Route a, b, and c.

	reagent			amount (g)	amount (mL)	density (g/mL)	total mass (g)	price (€/g or €/mL)	total price (€)
	Route a
	2,1,3-benzothiadiazole-4,7-bis(boronic acid pinacol ester)	0.247			0.247	138.000	34.086
	5-Bromo-2-thiophenecarboxaldehyde (1.607 g/mL at 25 °C)	0.314			0.314	3.170	0.995
	toluene				10	0.865	8.650	0.050	0.500
	K 2 CO 3 2mol/L (= 280 g/L)			5		1.400	0.140	0.196
	H 2 O				29	1	29.000
	Aliquat 336			4-5 drops = 0.25	0.884	0.221	0.150	0.033
	Pd(PPh 3 ) 4		0.045			0.045	30.000	1.350
	ethyl acetate			20	0.902	22.173	0.085	1.700
	dichloromethane			20	1.33	26.600	0.059	1.180
	petroleum ether 40-60°C			20	0.65	13.000	0.020	0.400
	total masses			101.650
	amount of product			0.230
	E-Factor route a			(total masses -amount)/amount		440.96
	cost (€/g)						175.83
	Route b
	reagent			amount (g)	amount (mL)	density (g/mL)	total mass (g)
	4,7-Dibromobenzo-2,1,3-thiadiazole a	0.100			0.100	6.600	0.660
	2-thiophenecarboxaldehyde	b	0.084			0.084	0.330	0.028
	Pd(OAc) 2	c		0.008			0.008	69.000	0.524
	PtBu2Me.HBF4		0.017	5		0.017	63.000	1.065
	PivOH			0.035			0.035	0.270	0.009
	K 2 CO 3			0.141			0.141	0.140	0.020
	toluene				4	0.865	3.460	0.050	0.173
	H 2 O				20	1	20.000
	ethyl acetate			20	0.902	22.173	0.085	1.700
	petroleum ether 40-60°C			20	0.65	13.000	0.020	0.400
	total masses			59.018
	amount of product			0.119
	E-Factor route b			(total masses -amount)/amount		494.95
	cost (€/g)						38.48
	Route c
	reagent			amount (g)	amount (mL)	density (g/mL)	total mass (g)
	4,7-Dibromobenzo-2,1,3-thiadiazole	0.500			0.500	6.600	3.300
	2-thiophenecarboxaldehyde	0.419			0.419	0.280	0.117
	DMA				6	0.937	5.622	0.040	0.240
	KOAc			0.334			0.334	0.300	0.100
	Pd(OAc)2		0.002			0.002	63.000	0.120
	H 2 O				20	1	20.000
	ethyl acetate			20	0.902	22.173	0.085	1.700
	petroleum ether 40-60°C			20	0.65	13.000	0.020	0.400
	total masses			62.050
	amount of product			0.430
	E-Factor route c			(total masses -amount)/amount		143.30
	cost (€/g)						13.90
	a, b, c: purchased from Interchim, Alfa Aesar, and Strem, respectively

Table A6 -

 A6 II: Molecule 5 obtained via Route c and different ratios (r), b, and c.

	Route c / r = 2.2
	reagent	amount (g)	amount (mL)	density (g/mL)	total mass (g)
	4,7-Dibromobenzo-2,1,3-thiadiazole	0.500			0.500	6.600	3.300
	2-thiophenecarboxaldehyde	0.419			0.419	0.280	0.117
	DMA		6	0.937	5.622	0.040	0.240
	KOAc	0.334			0.334	0.300	0.100
	Pd(OAc)2	0.002			0.002	63.000	0.120
	H 2 O		20	1	20.000
	ethyl acetate		20	0.902	22.173	0.085	1.700
	petroleum ether 40-60°C		20	0.65	13.000	0.020	0.400
	total masses		62.050
	amount of product		0.430
	E-Factor route c		(total masses -amount)/amount			143.30
	cost (€/g)						13.90
	Route c / r = 0.9
	reagent	amount (g)	amount (mL)	density (g/mL)	total mass (g)
	4,7-Dibromobenzo-2,1,3-thiadiazole	0.500			0.500	6.600	3.300
	2-thiophenecarboxaldehyde	0.172			0.172	0.280	0.048
	DMA		6	0.937	5.622	0.040	0.240
	KOAc	0.334			0.334	0.300	0.100
	Pd(OAc)2	0.002			0.002	63.000	0.120
	H 2 O		20	1	20.000
	ethyl acetate		20	0.902	22.173	0.085	1.700
	petroleum ether 40-60°C		20	0.65	13.000	0.020	0.400
	total masses		61.803
	amount of product		0.272
	E-Factor route c		(total masses -amount)/amount			226.22
	cost (€/g)						21.72
	Route c / r = 0.5
	reagent	amount (g)	amount (mL)	density (g/mL)	total mass (g)
	4,7-Dibromobenzo-2,1,3-thiadiazole	0.500			0.500	6.600	3.300
	2-thiophenecarboxaldehyde	0.095			0.095	0.280	0.027
	DMA		6	0.937	5.622	0.040	0.240
	KOAc	0.334			0.334	0.300	0.100
	Pd(OAc)2	0.002			0.002	63.000	0.120
	H 2 O		20	1	20.000
	ethyl acetate		20	0.902	22.173	0.085	1.700
	petroleum ether 40-60°C		20	0.65	13.000	0.020	0.400
	total masses		61.726
	amount of product		0.151
	E-Factor route c		(total masses -amount)/amount			407.78
	cost (€/g)						38.98

Table A6 -

 A6 III: Molecule 7 obtained via Routes a and c.

	reagent	amount (g)	amount (mL)	density (g/mL)	total mass (g)	price (€/g or €/mL)	total price (€)
	Route a
	2,1,3-benzothiadiazole-4,7-bis(boronic acid pinacol ester)	0.173			0.173	138.000	23.874
	5'-Bromo-2,2'-bithiophene-5-carboxaldehyde	0.305			0.305	54.000	16.470
	toluene		25	0.865	21.625	0.050	1.250
	K 2 CO 3 2mol/L (= 280 g/L)		5		1.400	0.140	0.196
	H 2 O		29	1	29.000
	Aliquat 336		4-5 drops = 0.25	0.884	0.221	0.150	0.033
	Pd(PPh 3 ) 4	0.039			0.039	30.000	1.155
	ethyl acetate		20	0.902	22.173	0.085	1.700
	dichloromethane		20	1.33	26.600	0.059	1.180
	petroleum ether 40-60°C		20	0.65	13.000	0.020	0.400
	total masses		114.536
	amount of product		0.230
	E-Factor route a		(total masses -amount)/amount			496.98
	cost (€/g)						201.12
	Route c
	reagent	amount (g)	amount (mL)	density (g/mL)	total mass (g)
	4,7-Dibromobenzo-2,1,3-thiadiazole	0.500			0.500	6.600	3.300
	2,2'-bithiophene-5-carbaldehyde d	0.727			0.727	37.000	26.899
	DMA		6	0.937	5.622	0.040	0.240
	KOAc	0.334			0.334	0.300	0.100
	Pd(OAc)2	0.002			0.002	63.000	0.120
	H 2 O		20	1	20.000
	ethyl acetate		20	0.902	22.173	0.085	1.700
	petroleum ether 40-60°C		20	0.65	13.000	0.020	0.400
	total masses		62.358
	amount of product		0.811
	E-Factor route c		(total masses -amount)/amount			75.89
	cost (€/g)						40.39
	Table A6-IV: Bz(T1CAO)2
	reagent	amount (g)	amount (mL)	density (g/mL) total mass (g)	price (€/g or €/mL)	total price (€)
	molecule 5	0.450			0.450	14.000	6.300
	triethylamine	1.680	2.3	0.73	1.680	0.283	0.651
	octylcyanoacetate	2.500	2.7	0.924	2.500	3.750	9.375
	dichloromethane		30	1.33	39.900	0.059	1.770
	water		10	1	10.000
	ethanol		10	1	10.000	0.032	0.320
	petroleum ether 40-60°C		30	0.65	19.500	0.020	0.600
	ethyl acetate		20	0.902	22.173	0.085	1.700
	total masses		106.203
	amount of product		0.460
	E-Factor route c		(total masses -amount)/amount			229.88
	cost (€/g)						45.03

Table A6

 A6

	-V: Bz(T1CAEH)2
	d: purchased from TCI Europe

Table A6 -

 A6 VI: Bz(T2CAO)2

d: purchased from TCI Europe

Table A6

 A6

	Annexes
	C -3.43328962670595 -6.77580969871453 -0.40196358392883 O -6.31949202870346 -8.41964690203890 0.95644379872917 H 18.30726452639465 5.60636222654416 1.91927226994220 Annex 7 H -4.36826928238882 -6.98741321944136 -0.91549299006198 C -5.60464428095372 -9.30620867626890 0.07775189926335 H 16.71909399250280 4.82016952045407 2.01471763754764
	reagent H -2.63201635444213 -6.69906220231025 -1.13506158299990 amount (g) H -6.37036890289432 -9.89076106764908 -0.42725464393152 H 17.89459276800478 4.31538602053937 0.76062413969671 Theoretical calculations H -3.21178882225456 -7.56508214262861 0.31208763110612 H -5.02637887369920 -8.75459230476138 -0.66199768091196 S 1.77432263918056 -2.50622974381978 0.46253500954627	amount (mL)	density (g/mL)	total mass (g)	price (€/g or €/mL)	total price (€)
	molecule 5 Table A7-I: Ground-state Cartesian coordinates of Bz(T1CAMe)2 in CH2Cl2 0.190 0.190 H -4.95026428432677 -9.96115771552098 0.64876157171191 C 3.16502154200480 -4.69071339837521 0.45238860524511	14.000	2.660
	-VII: Bz(T2CAEH)2 d: purchased from TCI Europe triethylamine 2-ethylhexylcyanoacetate d C 3.52188127462369 -3.50865462434769 -0.02312086412719 0.700 1.050 C -0.48959367210441 -4.11809784434672 0.65851645597074 C 1.84557438511921 -5.08899139730241 0.55876273749105 Table A7-II: Ground-state Cartesian coordinates of Bz(T2CAMe)2 in CH2Cl2 0.96 0.73 0.700 1.11 0.95 1.050 dichloromethane 20 1.33 26.600 water 10 1 10.000 ethanol 10 1 10.000 petroleum ether 40-60°C 20 0.65 13.000 ethyl acetate 8 0.902 7.216 total masses amount of product E-Factor route c cost (€/g) 68.756 0.180 (total masses -amount)/amount reagent amount (g) amount (mL) density (g/mL) total mass (g) molecule 7 0.500 0.500 triethylamine d 1.240 1.7 0.73 1.241 octylcyanoacetate 1.850 2 0.924 1.848 dichloromethane 40 1.33 53.200 ethanol 10 1 10.000 petroleum ether 40-60°C 20 0.65 13.000 ethyl acetate 15 0.902 13.530 total masses amount of product E-Factor route c cost (€/g) 93.319 0.640 (total masses -amount)/amount reagent amount (g) amount (mL) density (g/mL) total mass (g) molecule 7 0.500 0.500 triethylamine d 1.240 1.7 0.73 1.241 2-ethylhexylcyanoacetate 1.900 2 0.95 1.900 dichloromethane 40 1.33 53.200 ethanol 10 1 10.000 petroleum ether 40-60°C 20 0.65 13.000 ethyl acetate 15 0.902 13.530 total masses amount of product E-Factor route c cost (€/g) (total masses -amount)/amount 93.371 0.570 H 6.05939949349445 0.34079056482612 -0.16504781892921 N 8.34754466317542 -3.61580969983038 -0.39850122729142 S 7.78134230640971 -5.12995119833919 -0.41132145162661 N 6.19618920219010 -4.83712977703144 -0.29639133286658 C 6.03685701268153 -3.51060996373109 -0.24056115463085 C 7.29540800677292 -2.79546367637270 -0.30402323959877 C 4.78835992851491 -2.81384498607865 -0.13664327250968 C 4.88389087188389 -1.43301340167563 -0.13159319269990 C 6.10262632415653 -0.74003211549418 -0.19453001055549 C 7.33712935706796 -1.36252408278048 -0.26993413768217 S 8.56954225326217 1.12263303004226 -0.29344593719670 C 8.57762518478992 -0.61370506658070 -0.30053210408760 C 9.88321744961530 -1.08416482328796 -0.32723821496625 C 10.85023200733237 -0.07280873791571 -0.34172332566478 C 10.31254966787906 1.20514797741097 -0.33005747589957 H 10.11406053777243 -2.13560822455464 -0.33794518110014 H 11.91028457782639 -0.26775026570512 -0.36430544083503 H 3.98084514931512 -0.84213875439689 -0.05211909215821 C 10.91024054080739 2.49624361713146 -0.34754125491095 C 12.22597362628845 2.84551792901466 -0.37544226368309 H 10.23211346392808 3.34239410790516 -0.34899807262004 C 13.25365766837061 1.87128511437694 -0.44599225781470 N 14.07593508392382 1.06407276748994 -0.52184675213081 C 12.52617937758235 4.31799670827946 -0.44366363569693 O 11.69921152568739 5.09793067390376 -0.84241946595305 O 13.73593848469114 4.77769252563035 -0.07832427552227 C 14.62228655700479 4.05698470184201 0.79695399167566 H 15.18272033341919 4.82130202459810 1.33032028348594 H 14.06880680258562 3.45104458856012 1.51314960989640 H 15.30001802495926 3.43020128694078 0.22187604487296 S 2.00966048791308 -2.65601668233909 -0.06791409326934 C 3.29969902312667 -4.86470977431273 0.16077461143412 C 1.95110273866125 -5.20811511097430 0.28054812227799 H 4.10579180022806 -5.57562265383982 0.20879634646427 H 1.60914873140766 -6.21797277178447 0.43685724381129 C 1.09363248732899 -4.12343936431457 0.17869295131518 C -0.32578079743771 -4.03448690504576 0.22812633866813 C -1.24307122332730 -5.01685483006144 0.44691508661511 H -0.75912302713140 -3.05165612662592 0.08016765792875 C -0.85790637251548 -6.34501901647474 0.75767625068832 N -0.52905473371920 -7.41781575858922 1.02971138566497 C -2.68827552642340 -4.60505211956293 0.47144125465656 O -3.00294546205531 -3.46204849561969 0.68348862096789 O -3.64948579827646 -5.52730634719019 0.28269727148835 C -1.39658717366572 -3.06937534472384 0.65222623953923 H 3.99530298936181 -5.37505442176528 0.42495110068935 C 3.34397615474397 -3.36444939449446 0.32636020626414 H 5.71170221841585 0.59725040409583 C -2.72125058022714 -3.49263528908532 0.78181104250788 H 1.54205167621454 -6.12422485627459 0.62122769988280 0.33604861771635 C -2.86528133476066 -4.86863193742348 0.89620926289836 C 0.93810083039681 -4.02675237397898 0.57655824809700 N 8.17006785306471 -3.23946094206575 -0.03554584845209 S -1.29962235030570 -5.64455037526270 0.84119794860914 C -4.09154687801179 -5.57682302592942 0.95993992502733 S 7.67530567705331 -4.77716374647891 -0.10650983001549 H -1.10048602394481 -2.03578862440196 0.55040263589144 C -4.40354827483153 -6.89903933070771 1.07138459682644 N 6.07714047453702 -4.56190121214709 0.01497562164131 C 5.85610735592532 -3.24724074003635 H -3.57322494054688 -2.82782806479728 0.79160160722822 H -4.94434603641970 -4.90745885161013 0.94201463257166 0.11809057044102 C 10.59698983512611 2.89946833105371 0.30479440724380 C -3.40265785903024 -7.89808209036161 1.18533128113320 C 7.08159697655619 -2.47377458384515 0.08702339206960 C 10.03748937027617 4.16470205524521 0.38335695884938 N -2.57913705418001 -8.69869881250359 1.30626667705839 C 4.57650542985758 -2.61115745483943 0.24297622512345 C 10.99353816252661 5.18311180587623 0.39569035719274 C -5.86200384675508 -7.24650556482607 1.18726392493458 C 4.61525246756855 -1.22758313993114 0.29615897962728 C 12.30364276096685 4.72621212041563 0.33085552723408 O -6.65618917172524 -6.43689158081757 1.61133730130236 C 5.80285693937480 -0.47922823528582 0.26694904662554 S 12.32959386042040 2.97972766140094 0.25400939896717 O -6.30368037688369 -8.46085225919447 0.84561121731872 C 7.06417900642246 -1.04262597888611 0.17737173493329 H 8.97180456852473 4.33737539311894 0.42776438459249 C -5.58887393571605 -9.36513894264461 -0.03320888891006 S 8.20689171411887 1.49325753420363 0.26011223202984 H 10.75552695434228 6.23637500011609 0.44913652996973 H -6.36168934332649 -9.92394459598497 -0.55409161024597 C 8.27618377204463 -0.25390806920209 0.18646048265958 H -4.98825973683260 -8.81693467372442 -0.75569039155671 C 9.59292075747857 -0.67333201426819 0.15872968030302 Table A7-III: Ground-state Cartesian coordinates of the oxidized form of Bz(T2CAMe)2 in 0.283 0.272 1.080 1.199 0.059 1.180 0.032 0.320 0.020 0.400 0.085 0.680 380.98 37.28 price (€/g or €/mL) total price (€) 40.000 20.000 0.283 0.481 3.750 7.500 0.059 2.360 0.032 0.320 0.020 0.400 0.085 1.275 144.81 50.53 price (€/g or €/mL) total price (€) 40.000 20.000 0.283 0.481 1.080 2.160 0.059 2.360 0.032 0.320 0.020 0.400 0.085 1.275 162.81 47.36 H -4.97194163524490 -10.04015382695236 0.55447294346059 C 10.52110049668406 0.37790340196747 0.19873446970869 CH2Cl2 and its SOMO C -0.48044469748910 -4.10773905425685 0.67042760998330 C 9.94218639973843 1.62725227549200 0.25851277277009 C -1.41420800933187 -3.07509195807345 0.65571068841694 H 9.86536054995040 -1.71332442056120 0.11047916562074 C 3.33671792757404 -3.30059305982861 0.39114359685763 C -2.72574241836834 -3.52744729364600 0.75482458208817 H 11.59144275058109 0.22643970952988 0.18502190472244 H 5.64840368976492 0.66388324131837 0.37444214119899 C -2.83736672124867 -4.91285188219065 0.85689494936751 H 3.68730321007410 -0.67809032859434 0.38555380708297 N 8.15081500512980 -3.17737119824655 0.07029275484481 S -1.26416292317516 -5.65704663729099 0.82440607591467 C 13.43990941708773 5.57048047468734 0.31578361541561 S 7.67109453674612 -4.71979250559196 0.00388316830933 H -1.14495617339902 -2.03213706139874 0.56887190810596 C 14.77032782397694 5.27507408948561 0.27481763868192 N 6.07198745069536 -4.50731469209620 0.11164340929084 H -3.59210333612016 -2.88154915860793 0.75305222150126 H 13.21641479628499 6.63171533160719 0.32853753976167 C 5.84419067805861 -3.19707408279657 0.20621859841632 C 10.55731470334350 2.94453917556990 0.34554156083234 C 15.23455713908139 3.93997737312530 0.17830111862692 C 7.05980027657614 -2.42013381356566 0.18077595131835 C 10.03312583976361 4.23117722875742 0.42159259513404 N 15.60082764514565 2.84933609206961 0.07444803203303 C 4.55104793513201 -2.56379814781528 0.31210803302313 C 11.01482620368357 5.21827943040310 0.41073062995646 C 15.70960220292820 6.44115946507010 0.19850330813517 C 4.58056190166238 -1.15729285172429 0.34628067013296 C 12.31361456875667 4.71919347981185 0.32207442354456 O 15.33137381308462 7.50990204172196 -0.20926187518677 C 5.74726804847273 -0.41281890424129 0.32370893829720 S 12.29568557055873 2.98013323266671 0.25956560168408 O 16.99664382438647 6.30063069584158 0.56663560698190 C 7.03298184869401 -0.97849658502586 0.25814507621848 H 8.97444125331409 4.44057184443479 0.48526277644889 C 17.47137530548624 5.23783657076521 1.41113172980852 S 1.79641541514106 -2.55735446447629 C 3.16573924608899 -4.73363217317148 C 1.82426635480318 -5.12606442582424 H 3.99188952785725 -5.42099923780805 H 1.50946398875822 -6.15853894909413 C 0.93803258868694 -4.07027191816624 C 17.50835650046780 5.14854890296886 1.34210194539574 O -6.68179563059622 -6.36663242922519 1.65951633293394 O 17.04460236253065 6.19221426554201 0.44919424268413 C -5.88732329620406 -7.18103013107218 1.26243908937701 O 15.42606434722655 7.41873625337077 -0.38065525164538 N -2.59766368464667 -8.63623522357434 1.28970428077655 C 15.77220022527028 6.35153296594781 0.07372406867797 C -3.42613756945301 -7.83575358813215 1.20476979437528 N 15.58730804787895 2.78190795917506 -0.07506435852326 H -4.97437436571082 -4.85164533506268 1.03346465476218 C 15.23500872503406 3.87399816024423 0.05615588405826 C -4.43228552599023 -6.84051102983293 1.12427285908194 H 13.26402834976570 6.60540098557652 0.30966848070580 C -4.11888827127637 -5.51826120757370 1.02001685365769 C 14.79356801103553 5.21638398287138 0.17973873667706 0.53938186949476 C 13.47266743224797 5.54196900129400 0.27338999191996 0.54110191086338 H 3.64826986195373 -0.61217722487027 0.41333502606814 0.31849002741412 H 11.53529827992181 0.27275445000185 0.27913154205099 0.49137816733082 H 9.82903981614142 -1.64777928842230 0.22804246720034 0.37035412753538 C 9.87884116408878 1.69388879793314 0.32179679627597 0.43271380503160 C 10.46540820643730 0.42742439936936 0.28383800519813 H 17.81751112257238 4.40013982076536 0.80997031680404 C 9.55098243281038 -0.60823269071627 0.25729966386809 H 16.70455562011443 4.90336073507709 2.10833956307816 C 8.21346255546345 -0.18592301294641 0.27241350396583 H 18.30078524215240 5.66713313719825 1.96860270079816 S 8.14641583833998 1.56909958156015 0.32527815906977 H 10.80682748436899 6.27797274377046 0.46353807840767
	158

Table A7 -

 A7 IV: Ground-state Cartesian coordinates of the reduced form of Bz(T2CAMe)2 in CH2Cl2 and its SOMO SOMO of the reduced form of Bz(T2CAMe)2.

	C 7.10498918784651 -2.53074892664984 C 10.06390592353170 4.11944344323369	0.05964617846440 0.27597306449804
	C 4.58731071258894 -2.64606243358906 C 10.99914367659964 5.13798219871979	0.19815415005969 0.30576247725508
	C 4.63952078144021 -1.23991648876762 C 12.33445078592207 4.70651862145570	0.21931054447602 0.28010269452097
	C 5.81778635180327 -0.51139364321706 S 12.37637496883122 2.94475239265120	0.18411246245531 0.21395982966100
	C 7.09705949960382 -1.09259726235016 H 8.99577700999226 4.28654598833022	0.11908006368127 0.29171829579334
	S 8.23045142478012 H 10.74351680803598	1.44703422906438 6.18840764757638	0.18468612131428 0.34898889633153
	C 8.29413942674155 -0.31174499055040	0.12245549041981
	C 9.62917259128030 -0.72274993859803	0.09522910783444
	C 10.55000281356521	0.31937499642416	0.12615108393080
	C 9.98006219411350	1.58636110819332	0.17865214523154
	H 9.90810379511618 -1.76199101431194	0.05563882475298
	H 11.62023583240350	0.15999283294871	0.11233138189950
	H 3.71348800806978 -0.68238580830790	0.28440855706167
	C 13.43244048174864 C 14.80160407940782 H 13.16590144683315 C 15.33056190825830 N 15.74719799073552 C 15.67927981058541 O 15.28063012619659 O 16.97833881239366 C 17.50383022758477 H 18.29824454874847 H 16.74340552371990 H 17.91066638430890 S 1.80639107780418 -2.54739215729235 5.56816362210001 5.33389368875389 6.61889013692220 4.03051074343705 2.95849027201528 6.52037572763876 7.62180370360900 6.42306838416633 5.36913706282680 5.83452133104758 4.98107543737790 4.56832161925982 C 3.15107285517194 -4.75066668477514 C 1.81863807236999 -5.12512807926553 H 3.96608593861396 -5.45259888834614 H 1.50130822824963 -6.15685169106719 C 0.92331915053963 -4.06062934333361 C -4.12191108571751 -5.49822377651214 Figure A7-II: State, f, (nm), n Hole	0.31664661325832 0.33094108093965 0.35103684214115 0.20325980657642 0.06701038801340 0.34144775997717 0.00613341750629 0.70466022824209 1.54101097810199 2.12034890383726 2.21602535204497 0.92799696078296 0.38300661744709 0.35357573503387 0.48092821791760 0.31344282460768 0.54852373581769 0.51576136976472 1.04850944665940	Electron
	C -4.46737492650425 -6.83885200304498 S1, 2.07, 472.7, 0.93	1.15528710882607
	H -4.96757302688397 -4.81938048292557	1.06576450924957
	C -3.48946261511562 -7.85572391218218	1.23637856029514
	N -2.68535705521120 -8.68372233727379	1.33158026303652
	C -5.89879046849519 -7.16086410514386	1.31430922826040
	O -6.71424323390643 -6.34025466019162	1.69632322830673
	O -6.35157606224516 -8.41163497809232 S2, 0.088, 343, 0.88	1.06508568863206
	C -5.71187145382249 -9.31643256937167	0.13803191535565
	H -6.52116180562327 -9.86526092708895 -0.33866730773163
	H -5.14870095509862 -8.77200792740208 -0.61738111053521
	H -5.06155314376547 -10.00376828070193	0.67413509508489
	C -0.48439035766207 -4.11060884756480	0.64504575569410
	C -1.41027683705442 -3.05855002487043 S3, 0.422, 342.8, 0.93	0.65555776845411
	C 3.35895909524314 -3.37164724059587 C -2.72199906518843 -3.47668680203439	0.29022931381003 0.79628624648173
	H 5.73541349547162 C -2.88390991419423 -4.86518046592501 0.56799075606796	0.22243844999261 0.90997883894359
	N 8.18701116850452 -3.30502626286746 -0.03675564128488 S -1.30638920639706 -5.64501268110584 0.82810751056555
	S 7.68568188369451 -4.85590815688089 -0.08130038118649 H -1.11890644174052 -2.02247957081382 0.55640140750385
	N 6.07685184633117 -4.61300844285625 H -3.57040726821134 -2.80607443118679	0.02208076110208 0.81770566787584
	C 5.86740083934319 -3.29714320499971 C 10.63082213871279 2.84003049823419	0.09637432027708 0.22256915467928

  ) ......................................................................................... 27 Figure I-21: One difference of hopping transport from coherent (band) transport is that there is no need for charge carrier to move from one unit to the next. (a) This involves intrachain transport that may occur by a hopping mechanism, particularly when defects are existed in the chain. (b) It is possible that both coherent transport and hopping can occur in conjugated polymers, with the charge carrier hopping from one chain to another. (c) Only hopping transport exhibits in some polymers like poly(vinyl carbazole), due to lack of conjugated backbone.(125) ......................................................................................................................... 28 Figure I-22: Structures of some (a) electron donor and (b) electron acceptor units. ............... 29 Figure I-23: Chemical structures of representative polymers acting as donors in OPV devices. .................................................................................................................................................. 29 Figure I-24: The development of heterojunction solar cells based on polymers and small molecules.(30) .......................................................................................................................... 32

  H NMR spectrum of Bz(T1CAO)2. ...................................................................Figure V-4: 1 H NMR spectrum of Bz(T1CAEH)2. .................................................................Figure V-5: 1 H NMR spectrum of Bz(T2CAO)2. ...................................................................Figure V-6: 1 H NMR spectrum of Bz(T2CAEH)2. .................................................................

Table V -

 V 4: Yields for BrBzT1CHO obtained from different Route c (ii) conditions............. 133 Table V-5: Yields for SubPcBCl obtained from different conditions. ................................... 136

	Résumé de thèse
	INTRODUCTION GENERALE
	L'énergie est aujourd'hui un problème important et urgent auquel nous devons faire
	face, la demande mondiale en énergie renouvelable étant ne croissance constante. Les
	combustibles fossiles tels que le pétrole, le gaz, le charbon et d'autres énergies non
	renouvelables sont actuellement les principales sources d'énergie. Leur production et leur
	combustion sont devenues un problème sérieux pour notre environnement, en raison des
	fortes émissions en dioxyde de carbone (CO2), constituant un facteur clé du réchauffement
	climatique. Les combustibles fossiles ne sont pas en mesure de satisfaire nos les besoins
	futurs en énergie car leurs ressources sont limitées, ce qui conduit à un besoin urgent de
	sources d'énergie propres, renouvelables et durables. Atteindre cet objectif est l'un des plus
	grands défis de l'humanité.
	Résumé de thèse

Le soleil peut constituer pour notre planète une source inépuisable et infinie de l'énergie : la

  comme donneuses d'électrons, associées au PCBM comme accepteur d'électrons, ont été évaluées. Parmi les 2.3 millions de molécules virtuelles étudiées, environ 1000 auraient la capacité à mener à un PCE supérieur à 11%, la majorité des candidats menant à un PCE inférieur à 4%.(188) Toutefois, il convient de souligner que la plupart des candidats

	prometteurs seraient difficiles (voir impossible) à synthétiser en raison de leur complexité
	structurelle (hétérocycles complexes fusionnés). De plus, l'ajout de chaînes alkyles
	indispensable à rendre solubles ces molécules virtuelles constitue une difficulté de synthèse
	supplémentaire non négligeable. Parmi les 26 blocs de base, le 4,7-dibromobenzo-2,1,3-
	thiadiazole (diBrBz) figure parmi les fragments menant aux candidats les plus prometteurs, ce
	qui pourrait être un guide dans la conception de nos molécules. Par ailleurs, nous constatons
	que la majorité des structures moléculaires générées sont asymétriques, alors que
	généralement les molécules synthétisées, testées en OPV et décrites dans la littérature sont
	symétriques, pour des raisons de synthèse, principalement.
	Une autre stratégie récemment proposée consiste à réaliser un criblage virtuel à grande
	échelle par calculs théoriques. C'est précisément l'objet du projet « Clean Energy Project »
	(CEP),(187-189) initié en 2008 par le groupe d'Alán Aspuru-Guzik de l'Université de
	Harvard et soutenu par de nombreux contributeurs et collaborateurs externes.(190,191) Selon
	ce projet, 26 blocs génériques, constitués de cycles ou hétérocycles aromatiques, ont été
	utilisés pour générer 2,3 millions de motifs moléculaires, tous virtuels, constituant une base de
	données de référence massive concernant des matériaux semi-conducteurs organiques pour
	une application en photovoltaïque organique.(192) Les performances des molécules

Une méthode de conception moléculaire, très classiquement utilisée, consiste à imaginer des nouvelles molécules sur la base de la bibliographie, d'en réaliser la synthèse puis de les tester en cellule OPV. L'inconvénient majeur de cette méthode est qu'elle est coûteuse en temps et en moyens pour un résultat non garanti. virtuellement générées ont été évaluées en OPV par calculs théoriques : leurs structures ont été optimisées, puis les niveaux de leurs orbitales frontières calculés. Enfin, à l'aide du modèle

de Scharber,[START_REF] Scharber | Design rules for donors in bulk-heterojunction solar cells-Towards 10% energy-conversion efficiency[END_REF]

les performances de composants constitués de ces molécules, considérées Des investigations théoriques avancées d'une tout autre nature ont été réalisées afin d'étudier les interactions à l'interface d'un système bicouche, pour en donner une représentation visuelle simple et pédagogique. Ainsi, les groupes

et de

Tableau 1 :

 1 Une fois ces molécules conçues, des calculs théoriques ont été effectués pour prédire leurs propriétés électroniques. Les méthodesDFT (184) et TD-DFT (266-268) sont couramment utilisées et les résultats obtenus présentent de bon accords avec les résultats expérimentaux.(269, 270) Ainsi, pour prédire les propriétés électroniques de toutes les molécules conçues ci-dessus, nous avons effectué tous les calculs en utilisant la méthode DFT au niveau B3LYP/Def2-TZVP (-f). Pour faciliter le calcul, les chaînes terminales octyles (O) ou 2-éthylhexyle (EH) ont été remplacées par des groupes méthyle (Me). Les structures des molécules centrées sur le fragment benzothiadiazole ont été modélisées, la conformation des molécules et les angles dièdres entres les différents fragments ont été discutés. Il ressort de cette étude que les molécules cibles présentent des énergies d'orbitales frontières HOMO et LUMO compatibles avec une utilisation en qualité de donneurs d'électrons en association avec le PCBM comme accepteur. Les principaux résultats, ainsi que les paramètres OPV calculés selon le modèle de Scharber(61) pour des dispositifs conçus avec ces matériaux, ont été sont consignés dans le tableau suivant : Energies des orbitales frontières HOMO et LUMO des molécules, tension de circuit ouvert (Voc) et différence d'énergies des niveaux LUMO des molécules et du PCBM pour des dispositifs conçus à base de ces molécules associées au PCBM comme accepteur d'électron.Des calculs similaires ont été conduits sur les molécules à base de DTS. Ces molécules étant beaucoup plus complexes que les précédentes (voir Figure7), les calculs nécessaires nécessitent des temps plus long pour en optimiser la géométrie puis, par calculs de fréquence de vibration, vérifier que nous avons bien atteint bien un minimum d'énergie moléculaire correspondant à l'état fondamental le plus stable. Les calculs actuels n'ont pas encore, de notre point de vue, atteint tout à fait leur terme, mais nous pouvons estimer que les structures calculées sont actuellement très proches de structures à l'état fondamental, ce qui nous permet d'ores et déjà d'avoir une vision claire de l'influence de la longueur de conjugaison sur la structure moléculaire. En particulier, nous avons examiné l'effet de l'extension moléculaire sur les torsions des structures suivantes, les valeurs des angles étant données dans le Tableau Structures des molécules étudiées et angles dièdres examinés.

		HOMO	LUMO	Voc (V)	ΔE (eV)
	Bz(T1CAMe)2	-6.29	-3.89	1.7	0.4
	Bz(T2CAMe)2	-5.79	-3.64	1.2	0.66
	Bz(T3CAMe)2	-5.56	-3.51	0.96	0.8
	Bz(T4CAMe)2	-5.37	-3.39	0.77	0.9

* données non disponibles actuellement pour des raisons de durée de calcul.

Tableau 4 :

 4 Rendements de réaction, E-facteurs et coûts calculés pour Bz(T1CHO)2 obtenus pour les trois voies explorées. Enfin, ces intermédiaires conduisent aux molécules cibles par condensation de Knoevenagel, menée de façon classique La purification finale est réalisée par simple recristallisation dans l'acétate d'éthyle, ce qui réduit le problème des déchets liés au procédé de synthèse. Le tableau suivant résume les paramètres de synthèse des 4 molécules isolées. Rendements de la condensation Knoevenagel, E-facteurs globaux et coûts calculés pour les molécules cible obtenues via la Voie c. La synthèse des molécules base de DTS s'est avérée beaucoup plus complexe car le nombre d'étapes nécessaires était plus important et l'obtention et purification de certain synthons s'est révélée délicate. Les voies de synthèse des précurseurs di-aldéhydiques des molécules cibles sont schématisées ci-dessous : Voies de synthèse des dialdéhydes à base de DTS.Parmi les synthons nécessaires, nous avons isolé tous les réactifs (à gauche) des réactions cidessus ainsi que le produit dialdéhyde DTS(BzT2CHO)2. Par manque de temps, nous n'avons pas poursuivi les synthèses initialement prévues.

			Voie a	Voie b	Voie c
	Rd t (%)		100%		98%	71%
	E-factor (g/g)	441		495	143
	Coût (€/g)		176		38.5	14
	Tableau 5: Bz(T1CAO)2	Bz(T1CAEH)2	Bz(T2CAO)2	Bz(T2CAEH)2
	Rd t Knoevenagel	Cond.	51%	47%	76%	68%
	E-facteur (g/g)	global	230	380	144	162
	Coût total (€/g)	45	37	50	47

(a) (b)

HNMR spectrum of the crude product. All reaction yields are presented in TableV-4.

H NMR (300 MHz, CDCl3): δ 10.01 (s, 1H), 8.21 (d, J = 4.0 Hz, 1H), 7.95 (d, J = 7.7 Hz, 1H), 7.88 (d, J= 8 Hz, 1H), 7.87 (d, J= 4 Hz, 1H). 1 H NMR (400 MHz, CDCl3): δ 10.01 (s, 1H), 8.21 (d, J = 4.0 Hz, 1H), 7.95 (d, J = 7.6 Hz, 1H), 7.89 -7.86 (t, J = 4.0 Hz, J = 7.6 Hz,

2H).

Absorption spectra in solution were simulated using the orca_mapspc program that applies Gaussian-type lineshape function to the calculated transition with a defined full-width-halfmaximum of 1200cm-1. Different functionals have been tested to predict the absorption spectra that may help us to further understand optical properties of Bz(T1CAMe)2 and Bz(T2CAMe)2. It suggests that BHandHLYP method offers good agreement with experimental results in our case, as evidenced by Figure IV-2. The large absorption band that peaks at 525 nm for simulated Bz(T2CAMe)2 is observed at the same energy than that experimentally recorded. The maximum absorption wavelength of the large band simulated for Bz(T1CAMe)2 is 476 nm, which slightly blue shifted of 21 nm compared to that of experimental result. The most important contribution to this principal absorbance band originates from the HOMO to LUMO transition (as discussed in chapter II). All used chemicals and solvents were purchased from chemical companies and used as received, unless otherwise mentioned. All reactions were performed under ambient atmosphere and under air exposition unless special indication. 1 H experiments were recorded in the listed deuterated solvents (internal standard) on a DPX 400 Bruker Spectrometer.

Multiplicity of NMR signal was denoted as m (massif), s (singlet), d (doublet), t (triplet).

Mass analyses were performed at the Service de Spectrométrie de Masse de la Structure Fédérative Toulousaine en Chimie Moléculaire.

Elemental analyses (C, H, N) were carried out in the analysis service of the LCC laboratory.

Voltammetry measurements were carried out with a potentiostat Autolab PGSTAT100 controlled by GPES 4.09 software. Experiments were performed at room temperature in a homemade airtight three-electrode cell connected to a vacuum/argon line. The reference electrode consisted in a saturated calomel electrode (SCE) separated from the solution by a bridge compartment. The counter electrode was a platinum wire of ca 1cm² apparent surface.

The working electrode was a Pt microdisk (0.5mm diameter) or a glassy carbon (1mm diameter). The supporting electrolyte (nBu4N)[PF6] (Fluka, 99% electrochemical grade) was used as received and simply degassed under argon. Dichloromethane was freshly distilled over CaH2 prior to use. The solutions used during the electrochemical studies were typically 10 -3 mol.L -1 in compound and 0.1 mol.L -1 in supporting electrolyte. Before each measurement, the solutions were degassed by bubbling Ar and the working electrode was polished with a polishing machine (Presi P230).

UV-VIS-NIR absorption spectra were recorded on one Perkin Elmer Lambda 35 spectrometer, using dichloromethane as solvent. The solutions used for the electronic absorption analyses were typically about 10 -5 mol.L-1 in molecule.

Phase transition was determined by differential scanning calorimetry (DSC) thermograms, which were obtained on a DSC 204 NETZSCH system using 2-5 mg samples in 30 μl sample pans and a scan rate of 10°C min-1. ΔH is the enthalpy associated with each phase transition and it is calculated in kJ.mol-1. 343) Suzuki cross-coupling exhibits several advantages: commercial availability of many organoboronic acids and esters, gentle reaction conditions, insensitive to water presence, and the coupling is predominantly stereo-and regioselective.

Annexes Annex 1

These qualities allow Suzuki's cross-coupling method applicable for industrial produce.(344) However, one big disadvantage of this reaction is that by-products such as self-coupling products(345) or coupling products of phosphine-bound aryls are often formed. Recent developments in methods and catalyst have broadened its possible applications greatly, making the scope of the reaction reagents extend from aryls to alkyl, alkenyl and alkynyl.

Potassium trifluoroborates and organoboronate esters or the classic boronic acids are often used as the reagents.

The general mechanism for Suzuki cross-coupling is described in Figure A.2, which can also be used for other cross-coupling methods. It can be summarized in four steps.(344) First, oxidative addition of an organic halide to the Pd(0)-species to generate Pd(II). This is the ratedetermining step of the catalytic cycle. The organic halide in the presence of electrondeficient groups would be more reactive than those with electron-rich groups.(343) Second, metathesis that may involve an exchange of the anion adhered to the palladium for the anion of the base. Third, transmetallation transfers the organic group from metal boron to metal

Scheme list

Table list

Table list

Table I-