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Bordeaux

Bordeaux (, ; Gascon Bordèu ; Bordele) is a city on the river Garonne in the Gironde department, southwestern France. A port city, it is the capital of the Nouvelle-Aquitaine region, as well as the prefecture of the Gironde department. Its inhabitants are called "Bordelais (masculine) or "Bordelaises (feminine). The term "Bordelais" may also refer to the city and its surrounding region.

The city of Bordeaux proper had a population of 259,809 in 2020 within its small municipal territory of 49 km2, but together with its suburbs and exurbs the Bordeaux metropolitan area had a population of 1,376,375 that same year (Jan. 2020 census), the sixth-most populated in France after Paris, Lyon, Marseille, Lille, and Toulouse.

Bordeaux and 27 suburban municipalities form the Bordeaux Metropolis, an indirectly elected metropolitan authority now in charge of wider metropolitan issues. The Bordeaux Metropolis, with a population of 819,604 at the January 2020 census, is the fifth most populated metropolitan council in France after those of Paris, Marseille, Lyon and Lille.

Bordeaux is a world capital of wine: many châteaux and vineyards stand on the hillsides of the Gironde, and the city is home to the world's main wine fair, Vinexpo. Bordeaux is also one of the centers of gastronomy and business tourism for the organization of international congresses. It is a central and strategic hub for the aeronautics, military and space sector, home to international companies such as Dassault Aviation, Ariane Group, Safran and Thalès. The link with aviation dates back to 1910, the year the first airplane flew over the city. A crossroads of knowledge through university research, it is home to one of the only two megajoule lasers in the world, as well as a university population of more than 130,000 students within the Bordeaux Metropolis.

Bordeaux is an international tourist destination for its architectural and cultural heritage with more than 362 historic monuments, making it, after Paris, the city with the most listed or registered monuments in France. The "Pearl of Aquitaine" has been voted European Destination of the year in a 2015 online poll. The metropolis has also received awards and rankings by international organizations such as in 1957, Bordeaux was awarded the Europe Prize for its efforts in transmitting the European ideal. In June 2007, the Port of the Moon in historic Bordeaux was inscribed on the UNESCO World Heritage List, for its outstanding architecture and urban ensemble and in recognition of Bordeaux's international importance over the last 2000 years. Bordeaux is also ranked as a Sufficiency city by the Globalization and World Cities Research Network.

5th century BC to 11th century AD

Around 300 BC, the region was the settlement of a Celtic tribe, the Bituriges Vivisci, named the town Burdigala, probably of Aquitanian origin.

In 107 BC, the Battle of Burdigala was fought by the Romans who were defending the Allobroges, a Gallic tribe allied to Rome, and the Tigurini led by Divico. The Romans were defeated and their commander, the consul Lucius Cassius Longinus, was killed in battle.

The city came under Roman rule around 60 BC, and it became an important commercial centre for tin and lead. During this period were built the amphitheatre and the monument Les Piliers de Tutelle.

In 276, it was sacked by the Vandals. The Vandals attacked again in 409, followed by the Visigoths in 414, and the Franks in 498, and afterwards the city fell into a period of relative obscurity.

In the late sixth century the city re-emerged as the seat of a county and an archdiocese within the Merovingian kingdom of the Franks, but royal Frankish power was never strong. The city started to play a regional role as a major urban center on the fringes of the newly founded Frankish Duchy of Vasconia. Around 585 Gallactorius was made Count of Bordeaux and fought the Basques.

In 732, the city was plundered by the troops of Abd er Rahman who stormed the fortifications and overwhelmed the Aquitanian garrison. Duke Eudes mustered a force to engage the Umayyads, eventually engaging them in the Battle of the River Garonne somewhere near the river Dordogne. The battle had a high death toll, and although Eudes was defeated he had enough troops to engage in the Battle of Poitiers and so retain his grip on Aquitaine.

In 737, following his father Eudes's death, the Aquitanian duke Hunald led a rebellion to which Charles responded by launching an expedition that captured Bordeaux. However, it was not retained for long, during the following year the Frankish commander clashed in battle with the Aquitanians but then left to take on hostile Burgundian authorities and magnates. In 745 Aquitaine faced another expedition where Charles's sons Pepin and Carloman challenged Hunald's power and defeated him. Hunald's son Waifer replaced him and confirmed Bordeaux as the capital city (along with Bourges in the north).

During the last stage of the war against Aquitaine (760–768), it was one of Waifer's last important strongholds to fall to the troops of King Pepin the Short. Charlemagne built the fortress of Fronsac (Frontiacus, Franciacus) near Bordeaux on a hill across the border with the Basques (Wascones), where Basque commanders came and pledged their loyalty (769).

In 778, Seguin (or Sihimin) was appointed count of Bordeaux, probably undermining the power of the Duke Lupo, and possibly leading to the Battle of Roncevaux Pass. In 814, Seguin was made Duke of Vasconia, but was deposed in 816 for failing to suppress a Basque rebellion. Under the Carolingians, sometimes the Counts of Bordeaux held the title concomitantly with that of Duke of Vasconia. They were to keep the Basques in check and defend the mouth of the Garonne from the Vikings when they appeared in c. 844. In Autumn 845, the Vikings were raiding Bordeaux and Saintes, count Seguin II marched on them but was captured and executed.

Although the port of Bordeaux was a buzzing trade center, the stability and success of the city was threatened by Viking and Norman incursions and political instability. The restoration of the Ramnulfid Dukes of Aquitaine under William IV and his successors (known as the House of Poitiers) brought continuity of government.

12th century to 15th century, the English era

From the 12th to the 15th century, Bordeaux flourished once more following the marriage of Eléonore, Duchess of Aquitaine and the last of the House of Poitiers, to Henry II Plantagenêt, Count of Anjou and the grandson of Henry I of England, who succeeded to the English crown months after their wedding, bringing into being the vast Angevin Empire, which stretched from the Pyrenees to Ireland. After granting a tax-free trade status with England, Henry was adored by the locals as they could be even more profitable in the wine trade, their main source of income, and the city benefited from imports of cloth and wheat. The belfry (Grosse Cloche) and city cathedral St-André were built, the latter in 1227, incorporating the artisan quarter of Saint-Paul. Under the terms of the Treaty of Brétigny it became briefly the capital of an independent state (1362–1372) under Edward, the Black Prince, but after the Battle of Castillon (1453) it was annexed by France.

15th century to 17th century
In 1462, Bordeaux created a local parliament.

Bordeaux adhered to the Fronde, being effectively annexed to the Kingdom of France only in 1653, when the army of Louis XIV entered the city.

18th century, the golden era
The 18th century saw another golden age of Bordeaux. The Port of the Moon supplied the majority of Europe with coffee, cocoa, sugar, cotton and indigo, becoming France's busiest port and the second busiest port in the world after London. Many downtown buildings (about 5,000), including those on the quays, are from this period.

Bordeaux was also a major trading centre for slaves. In total, the Bordeaux shipowners deported 150,000 Africans in some 500 expeditions.

French Revolution: political disruption and loss of the most profitable colony
At the beginning of the French Revolution (1789), many local revolutionaries were members of the Girondists. This Party represented the provincial bourgeoisie, favorable towards abolishing aristocracy privileges, but opposed to the Revolution's social dimension. The Gironde valley's economic value and significance was satiated by the city's commercial power which was in dire contrast to the emerging widespread poverty affecting its inhabitants. Trade and commerce were the driving factors in the region's economic prosperity, still this resulted in a significant number of locals struggling to survive on a daily basis due to lack of food and resources. This socioeconomic disparity served as fertile ground for discontent, sparking frequent episodes of mass unrest well before the tumultuous events of 1783. [1]

In 1793, the Montagnards led by Robespierre and Marat came to power. Fearing a bourgeois misappropriation of the Revolution, they executed a great number of Girondists. During the purge, the local Montagnard Section renamed the city of Bordeaux "Commune-Franklin" (Franklin-municipality) in homage to Benjamin Franklin.

At the same time, in 1791, a slave revolt broke out at Saint-Domingue (current Haiti), the most profitable of the French colonies.In the lively era of the 18th century, Bordeaux emerged as a center of economic activity, particularly known at first for its successful wine trade. The city's placement along the Gironde River was very strategic, helping to facilitate the transportation of produce to markets both internationally and domestically, which led to an increase in exports and Bordeaux's economic prosperity. There was a significant transformation to the economic landscape of Bordeaux in 1785, which was spurred by the attraction of large profits, traders and merchants in Bordeaux began to turn their attention to the slave trade. This was a very important moment in the city's economic history seeing as it diversified its commercial expansion, at a serious moral cost. This introduced a new layer of difficulty to Bordeaux's economic activities. Even though it brought along significant wealth to certain segments of society, it complicated the socio-economic inconsistencies within the region. The entry into the slave trade brought even more tension within Bordeaux society. The trade exacerbated the divide between an elite with growing wealth and those living in poverty. This economic divide laid out the foundation for the mass unrest that would break out in the French Revolution. [2]

Three years later, the Montagnard Convention abolished slavery. In 1802, Napoleon revoked the manumission law but lost the war against the army of former slaves. In 1804, Haiti became independent. The loss of this "Pearl" of the West Indies generated the collapse of Bordeaux's port economy, which was dependent on the colonial trade and trade in slaves.

Towards the end of the Peninsular War of 1814, the Duke of Wellington sent William Beresford with two divisions and seized Bordeaux, encountering little resistance. Bordeaux was largely anti-Bonapartist and the majority supported the Bourbons. The British troops were treated as liberators. Distinguished historian of the French revolution Suzanne Desan explains that "examining intricate local dynamics" is essential to studying the Revolution by region. [3]

19th century, rebirth of the economy
From the Bourbon Restoration, the economy of Bordeaux was rebuilt by traders and shipowners. They engaged to construct the first bridge of Bordeaux, and customs warehouses. The shipping traffic grew through the new African colonies.

Georges-Eugène Haussmann, a longtime prefect of Bordeaux, used Bordeaux's 18th-century large-scale rebuilding as a model when he was asked by Emperor Napoleon III to transform the quasi-medieval Paris into a "modern" capital that would make France proud. Victor Hugo found the town so beautiful he said: "Take Versailles, add Antwerp, and you have Bordeaux".

In 1870, at the beginning of the Franco-Prussian war against Prussia, the French government temporarily relocated to Bordeaux from Paris. That recurred during World War I and again very briefly during World War II, when it became clear that Paris would fall into German hands.

20th century

During World War II, Bordeaux fell under German occupation.

In May and June 1940, Bordeaux was the site of the life-saving actions of the Portuguese consul-general, Aristides de Sousa Mendes, who illegally granted thousands of Portuguese visas, which were needed to pass the Spanish border, to refugees fleeing the German occupation.

From 1941 to 1943, the Italian Royal Navy established BETASOM, a submarine base at Bordeaux. Italian submarines participated in the Battle of the Atlantic from that base, which was also a major base for German U-boats as headquarters of 12th U-boat Flotilla. The massive, reinforced concrete U-boat pens have proved impractical to demolish and are now partly used as a cultural center for exhibitions.

21st century, listed as World heritage
In 2007, 40% of the city surface area, located around the Port of the Moon, was listed as World heritage sites. Unesco inscribed Bordeaux as "an inhabited historic city, an outstanding urban and architectural ensemble, created in the age of the Enlightenment, whose values continued up to the first half of the 20th century, with more protected buildings than any other French city except Paris".

Geography
Bordeaux is located close to the European Atlantic coast, in the southwest of France and in the north of the Aquitaine region. It is around 500 km southwest of Paris. The city is built on a bend of the river Garonne, and is divided into two parts: the right bank to the east and left bank in the west. Historically the left bank is more developed because when flowing outside the bend, the water makes a furrow of the required depth to allow the passing of merchant ships, which used to offload on this side of the river. But, today, the right bank is developing, including new urban projects. In Bordeaux, the Garonne River is accessible to ocean liners through the Gironde estuary. The right bank of the Garonne is a low-lying, often marshy plain.

Climate
Bordeaux's climate can be classified as oceanic (Köppen climate classification Cfb), bordering on a humid subtropical climate (Cfa). However, the Trewartha climate classification system classifies the city as solely humid subtropical, due to a recent rise in temperatures related – to some degree or another – to climate change and the city's urban heat island.

The city enjoys cool to mild, wet winters, due to its relatively southerly latitude, and the prevalence of mild, westerly winds from the Atlantic. Its summers are warm and somewhat drier, although wet enough to avoid a Mediterranean classification. Frosts occur annually, but snowfall is quite infrequent, occurring for no more than 3–4 days a year. The summer of 2003 set a record with an average temperature of 23.3 °C, while February 1956 was the coldest month on record with an average temperature of −2.00 °C at Bordeaux Mérignac-Airport.

Economy
Bordeaux is a major centre for business in France as it has the sixth largest metropolitan population in France. It serves as a major regional center for trade, administration, services and industry.

Wine

The vine was introduced to the Bordeaux region by the Romans, probably in the mid-first century, to provide wine for local consumption, and wine production has been continuous in the region since.

Bordeaux wine growing area has about 116160 ha of vineyards, 57 appellations, 10,000 wine-producing estates (châteaux) and 13,000 grape growers. With an annual production of approximately 960 million bottles, the Bordeaux area produces large quantities of everyday wine as well as some of the most expensive wines in the world. Included among the latter are the area's five premier cru (First Growth) red wines (four from Médoc and one, Château Haut-Brion, from Graves), established by the Bordeaux Wine Official Classification of 1855:

Both red and white wines are made in the Bordeaux region. Red Bordeaux wine is called claret in the United Kingdom. Red wines are generally made from a blend of grapes, and may be made from Cabernet Sauvignon, Merlot, Cabernet Franc, Petit verdot, Malbec, and, less commonly in recent years, Carménère.

White Bordeaux is made from Sauvignon blanc, Sémillon, and Muscadelle. Sauternes is a sub-region of Graves known for its intensely sweet, white, dessert wines such as Château d'Yquem.

Because of a wine glut (wine lake) in the generic production, the price squeeze induced by an increasingly strong international competition, and vine pull schemes, the number of growers has recently dropped from 14,000 and the area under vine has also decreased significantly. In the meantime, the global demand for first growths and the most famous labels markedly increased and their prices skyrocketed.

The Cité du Vin, a museum as well as a place of exhibitions, shows, movie projections and academic seminars on the theme of wine opened its doors in June 2016.

Others
The Laser Mégajoule will be one of the most powerful lasers in the world, allowing fundamental research and the development of the laser and plasma technologies.

Some 15,000 people work for the aeronautic industry in Bordeaux. The city has some of the biggest companies including Dassault, EADS Sogerma, Snecma, Thales, SNPE, and others. The Dassault Falcon private jets are built there as well as the military aircraft Rafale and Mirage 2000, the Airbus A380 cockpit, the boosters of Ariane 5, and the M51 SLBM missile.

Tourism, especially wine tourism, is a major industry. Globelink.co.uk mentioned Bordeaux as the best tourist destination in Europe in 2015. Gourmet Touring is a tourism company operating in the Bordeaux wine region.

Access to the port from the Atlantic is via the Gironde estuary. Almost nine million tonnes of goods arrive and leave each year.

Major companies
This list includes indigenous Bordeaux-based companies and companies that have major presence in Bordeaux, but are not necessarily headquartered there.
 * Arena
 * Groupe Bernard
 * Groupe Castel
 * Cdiscount
 * Dassault
 * Jock
 * Marie Brizard
 * McKesson Corporation
 * Oxbow
 * Ricard
 * Sanofi Aventis
 * Smurfit Kappa
 * Snecma
 * Solectron
 * Thales Group

Population
In January 2020, there were 259,809 inhabitants in the city proper (commune) of Bordeaux. The commune (including Caudéran which was annexed by Bordeaux in 1965) had its largest population of 284,494 at the 1954 census. The majority of the population is French, but there are sizable groups of Italians, Spaniards (Up to 20% of the Bordeaux population claim some degree of Spanish heritage), Portuguese, Turks, Germans.

The built-up area has grown for more than a century beyond the municipal borders of Bordeaux due to the small size of the commune (49 km2) and urban sprawl, so that by January 2020 there were 1,376,375 people living in the overall 6316 km2 metropolitan area (aire d'attraction) of Bordeaux, only a fifth of whom lived in the city proper.

Municipal administration

The Mayor of the city is the environmentalist Pierre Hurmic.

Bordeaux is the capital of five cantons and the Prefecture of the Gironde and Aquitaine.

The town is divided into three districts, the first three of Gironde. The headquarters of Urban Community of Bordeaux Mériadeck is located in the neighbourhood and the city is at the head of the Chamber of Commerce and Industry that bears his name.

The number of inhabitants of Bordeaux is greater than 250,000 and less than 299,999 so the number of municipal councilors is 65. They are divided according to the following composition:

Mayors of Bordeaux
Since the Liberation (1944), there have been six mayors of Bordeaux:
 * RPR was renamed to UMP in 2002 which was later renamed to LR in 2015.

Presidential elections of 2007
At the 2007 presidential election, the Bordelais gave 31.37% of their votes to Ségolène Royal of the Socialist Party against 30.84% to Nicolas Sarkozy, president of the UMP. Then came François Bayrou with 22.01%, followed by Jean-Marie Le Pen who recorded 5.42%. None of the other candidates exceeded the 5% mark. Nationally, Nicolas Sarkozy led with 31.18%, then Ségolène Royal with 25.87%, followed by François Bayrou with 18.57%. After these came Jean-Marie Le Pen with 10.44%, none of the other candidates exceeded the 5% mark. In the second round, the city of Bordeaux gave Ségolène Royal 52.44% against 47.56% for Nicolas Sarkozy, the latter being elected President of the Republic with 53.06% against 46.94% for Ségolène Royal. The abstention rates for Bordeaux were 14.52% in the first round and 15.90% in the second round.

Parliamentary elections of 2007
In the parliamentary elections of 2007, the left won eight constituencies against only three for the right. It should be added that after the partial 2008 elections, the eighth district of Gironde switched to the left, bringing the count to nine. In Bordeaux, the left was for the first time in its history the majority as it held two of three constituencies following the elections. In the first division of the Gironde, the outgoing UMP MP Chantal Bourragué was well ahead with 44.81% against 25.39% for the Socialist candidate Beatrice Desaigues. In the second round, it was Chantal Bourragué who was re-elected with 54.45% against 45.55% for his socialist opponent. In the second district of Gironde the UMP mayor and all new Minister of Ecology, Energy, Sustainable Development and the Sea Alain Juppé confronted the General Counsel PS Michèle Delaunay. In the first round, Alain Juppé was well ahead with 43.73% against 31.36% for Michèle Delaunay. In the second round, it was finally Michèle Delaunay who won the election with 50.93% of the votes against 49.07% for Alain Juppé, the margin being only 670 votes. The defeat of the so-called constituency "Mayor" showed that Bordeaux was rocking increasingly left. Finally, in the third constituency of the Gironde, Noël Mamère was well ahead with 39.82% against 28.42% for the UMP candidate Elizabeth Vine. In the second round, Noël Mamère was re-elected with 62.82% against 37.18% for his right-wing rival.

Municipal elections of 2008
In 2008 municipal elections saw the clash between mayor of Bordeaux, Alain Juppé and the President of the Regional Council of Aquitaine Socialist Alain Rousset. The PS had put up a Socialist heavyweight in the Gironde and had put great hopes in this election after the victory of Ségolène Royal and Michèle Delaunay in 2007. However, after a rather exciting campaign it was Alain Juppé who was widely elected in the first round with 56.62 percent, far ahead of Alain Rousset who garnered 34.14 percent of the vote. At present, of the eight cantons that has Bordeaux, five are held by the PS and three by the UMP, the left eating a little each time into the right's numbers.

European elections of 2009
In the European elections of 2009, Bordeaux voters largely voted for the UMP candidate Dominique Baudis, who won 31.54% against 15.00% for PS candidate Kader Arif. The candidate of Europe Ecology José Bové came second with 22.34%. None of the other candidates reached the 10% mark. The 2009 European elections were like the previous ones in eight constituencies. Bordeaux is located in the district "Southwest", here are the results:

UMP candidate Dominique Baudis: 26.89%. His party gained four seats. PS candidate Kader Arif: 17.79%, gaining two seats in the European Parliament. Europe Ecology candidate Bove: 15.83%, obtaining two seats. MoDem candidate Robert Rochefort: 8.61%, winning a seat. Left Front candidate Jean-Luc Mélenchon: 8.16%, gaining the last seat. At regional elections in 2010, the Socialist incumbent president Alain Rousset won the first round by totaling 35.19% in Bordeaux, but this score was lower than the plan for Gironde and Aquitaine. Xavier Darcos, Minister of Labour followed with 28.40% of the votes, scoring above the regional and departmental average. Then came Monique De Marco, Green candidate with 13.40%, followed by the member of Pyrenees-Atlantiques and candidate of the MoDem Jean Lassalle who registered a low 6.78% while qualifying to the second round on the whole Aquitaine, closely followed by Jacques Colombier, candidate of the National Front, who gained 6.48%. Finally the candidate of the Left Front Gérard Boulanger with 5.64%, no other candidate above the 5% mark. In the second round, Alain Rousset had a tidal wave win as national totals rose to 55.83%. If Xavier Darcos largely lost the election, he nevertheless achieved a score above the regional and departmental average obtaining 33.40%. Jean Lassalle, who qualified for the second round, passed the 10% mark by totaling 10.77%. The ballot was marked by abstention amounting to 55.51% in the first round and 53.59% in the second round.

Only candidates obtaining more than 5% are listed

2017 elections
Bordeaux voted for Emmanuel Macron in the presidential election. In the 2017 parliamentary election, La République En Marche! won most of the constituencies in Bordeaux.

2019 European elections
Bordeaux voted in the 2019 European Parliament election in France.

Municipal elections of 2020
After 73 years of right-of-centre rule, the ecologist Pierre Hurmic (EELV) came in ahead of Nicolas Florian (LR/LaREM).

Parliamentary representation
The city area is represented by the following constituencies: Gironde's 1st, Gironde's 2nd, Gironde's 3rd, Gironde's 4th, Gironde's 5th, Gironde's 6th, Gironde's 7th.

University

During Antiquity, a first university had been created by the Romans in 286. The city was an important administrative centre and the new university had to train administrators. Only rhetoric and grammar were taught. Ausonius and Sulpicius Severus were two of the teachers.

In 1441, when Bordeaux was an English town, the Pope Eugene IV created a university by demand of the archbishop Pey Berland. In 1793, during the French Revolution, the National Convention abolished the university, and replace them with the École centrale in 1796. In Bordeaux, this one was located in the former buildings of the college of Guyenne. In 1808, the university reappeared with Napoleon. Bordeaux accommodates approximately 70,000 students on one of the largest campuses of Europe (235 ha).

Schools
Bordeaux has numerous public and private schools offering undergraduate and postgraduate programs.

Engineering schools:
 * Arts et Métiers ParisTech, graduate school of industrial and mechanical engineering
 * ESME-Sudria, graduate school of engineering
 * École nationale supérieure d'électronique, informatique, télécommunications, mathématique et mécanique de Bordeaux (ENSEIRB-MATMECA)
 * École supérieure de technologie des biomolécules de Bordeaux
 * École nationale supérieure des sciences agronomiques de Bordeaux Aquitaine
 * École nationale supérieure de chimie et physique de Bordeaux
 * École pour l'informatique et les nouvelles technologies
 * Institut des sciences et techniques des aliments de Bordeaux
 * Institut de cognitique
 * École supérieure d'informatique
 * École privée des sciences informatiques

Business and management schools:
 * The Bordeaux MBA (International College of Bordeaux)
 * IUT Techniques de Commercialisation of Bordeaux (business school)
 * INSEEC Business School (Institut des hautes études économiques et commerciales)
 * KEDGE Business School (former BEM – Bordeaux Management School)
 * Vatel Bordeaux International Business School
 * E-Artsup
 * Institut supérieur européen de gestion group
 * Institut supérieur européen de formation par l'action

Other:
 * École nationale de la magistrature (National school for the judiciary)
 * École d'architecture et de paysage de Bordeaux
 * École des beaux-arts de Bordeaux
 * École française des attachés de presse et des professionnels de la communication (EFAP)
 * Conservatoire national des arts et métiers d'Aquitaine (CNAM)
 * École des Avocats ALIENOR de Bordeaux (law school)

Weekend education
The École Compleméntaire Japonaise de Bordeaux (ボルドー日本語補習授業校), a part-time Japanese supplementary school, is held in the Salle de L'Athénée Municipal in Bordeaux.

Heritage and architecture
Bordeaux is classified "City of Art and History". The city is home to 362 monuments historiques (only Paris has more in France) with some buildings dating back to Roman times. Bordeaux, Port of the Moon, has been inscribed on UNESCO World Heritage List as "an outstanding urban and architectural ensemble".

Bordeaux is home to one of Europe's biggest 18th-century architectural urban areas, making it a sought-after destination for tourists and cinema production crews. It stands out as one of the first French cities, after Nancy, to have entered an era of urbanism and metropolitan big scale projects, with the team Gabriel father and son, architects for King Louis XV, under the supervision of two intendants (Governors), first Nicolas-François Dupré de Saint-Maur then the Marquis de Tourny.

Saint-André Cathedral, Saint-Michel Basilica and Saint-Seurin Basilica are part of the World Heritage Sites of the Routes of Santiago de Compostela in France. The organ in Saint-Louis-des-Chartrons is registered on the French monuments historiques.

Buildings
Main sights include:
 * Place de la Bourse (1735–1755), designed by the Royal architect Jacques Gabriel as landscape for an equestrian statue of Louis XV, now replaced by the Fountain of the Three Graces.
 * Grand Théâtre (1780), a large neoclassical theater built in the 18th century.
 * Allées de Tourny
 * Cours de l'Intendance
 * Place du Chapelet
 * Place du Parlement
 * Place des Quinconces, the largest square in France.
 * Monument aux Girondins
 * Place Saint-Pierre
 * Pont de pierre (1822)
 * Bordeaux Cathedral (Saint André), consecrated by Pope Urban II in 1096 and dedicated to the Apostle Saint Andrew. Of the original Romanesque edifice only a wall in the nave remains. The Royal Door is from the early 13th century, while the rest of the construction is mostly from the 14th and 15th centuries.
 * Tour Pey-Berland (1440–1450), a massive, quadrangular Gothic tower annexed to the cathedral.
 * Sainte-Croix church: This church, dedicated to the Holy Cross, stands on the site of a seventh-century abbey destroyed by the Saracens. Rebuilt under the Carolingians, it was again destroyed by the Normans in 845 and 864. The present building was erected and was built in the late 11th and early 12th centuries. The façade is in Romanesque style.
 * The Gothic Saint Michel Basilica, constructed between the end of the 14th century and the 16th century.
 * Basilica of Saint Severinus, the oldest church in Bordeaux, built in the early sixth century on the site of a palaeo-Christian necropolis. It has an 11th-century portico, while the apse and transept are from the 12th. The 13th-century nave has chapels from the 11th and the 14th centuries. The ancient crypt houses tombs of the Merovingian family.
 * Église Saint-Pierre, Gothic church
 * Église Saint-Éloi, Gothic church
 * Église Saint-Bruno, baroque church decorated with frescoes
 * Église Notre-Dame, baroque church
 * Église Saint-Paul-Saint-François-Xavier, baroque church
 * Palais Rohan, once the archbishop's residence, now city hall
 * , the remains of a late second-century Roman amphitheatre
 * Porte Cailhau, a medieval gatehouse in the old city walls.
 * La Grosse Cloche (15th century), the second remaining gate in the medieval walls. It was the belfry of the old Town Hall. It consists of two 40 m circular towers and a central bell tower housing a bell weighing 7800 kg. The clock is from 1759.
 * Grande Synagogue, completed 1882
 * Rue Sainte-Catherine, the longest pedestrian street in France
 * Darwin ecosystem, alternative place into former military barracks
 * The BETASOM submarine base

Contemporary architecture

 * Cité Frugès, district of Pessac, built by Le Corbusier, 1924–1926, listed as UNESCO heritage
 * Fire Station, la Benauge, Claude Ferret/Adrien Courtois/Yves Salier, 1951–1954
 * Mériadeck district, 1960–70's
 * Court of first instance, Richard Rogers, 1998
 * CTBA, wood and furniture research center, A. Loisier, 1998
 * Hangar 14 on the Quai des Chartrons, 1999
 * The Management Science faculty on the Bastide, Anne Lacaton/Jean-Philippe Vassal, 2006
 * The Jardin botanique de la Bastide, Catherine Mosbach/Françoise Hélène Jourda/Pascal Convert, 2007
 * The Nuyens School complex on the Bastide, Yves Ballot/Nathalie Franck, 2007
 * Seeko'o Hotel on the Quai de Bacalan, King Kong architects, 2007
 * Matmut Atlantique stadium, Herzog & de Meuron, 2015
 * Cité du Vin, XTU architects, Anouk Legendre & Nicolas Desmazières, 2016
 * MECA, Maison de l'Économie Créative et de la culture de la Région Nouvelle-Aquitaine, Bjarke Ingels, 2019

Museums

 * Musée des Beaux-Arts (Fine arts museum), one of the finest painting galleries in France with paintings by painter such as Tiziano, Veronese, Rubens, Van Dyck, Frans Hals, Claude, Chardin, Delacroix, Renoir, Seurat, Redon, Matisse and Picasso.
 * Musée d'Aquitaine (archeological and history museum)
 * Musée du Vin et du Négoce (museum of the wine trade)
 * Musée des Arts Décoratifs et du Design (museum of decorative arts and design)
 * Musée d'Histoire Naturelle (natural history museum)
 * Musée Mer Marine (Sea and Navy museum)
 * Cité du Vin
 * CAPC musée d'art contemporain de Bordeaux (modern art museum)
 * Musée national des douanes (history of French customs)
 * Bordeaux Patrimoine Mondial (architectural and heritage interpretation centre)
 * Musée d'ethnologie (ethnology museum)
 * Institut culturel Bernard Magrez, modern and streetart museum into an 18th-century mansion
 * Cervantez Institute (into the house of Goya)
 * Cap Sciences
 * Centre Jean Moulin

Memory of slavery
Slavery was part of a growing drive for the city. Firstly, during the 18th and 19th centuries, Bordeaux was an important slave port, which saw some 500 slave expeditions that cause the deportation of 150,000 Africans by Bordeaux shipowners. Secondly, even though the "Triangular trade" represented only 5% of Bordeaux's wealth, the city's direct trade with the Caribbean, that accounted for the other 95%, concerns the colonial stuffs made by the slave (sugar, coffee, cocoa). And thirdly, in that same period, a major migratory movement by Aquitanians took place to the Caribbean colonies, with Saint-Domingue (now Haiti) being the most popular destination. 40% of the white population of the island came from Aquitaine. They prospered with plantations incomes, until the first slave revolts which concluded in 1848 in the final abolition of slavery in France.

A statue of Modeste Testas, an Ethiopian woman who was enslaved by the Bordeaux-based Testas brothers was unveiled in 2019. She was trafficked by them from West Africa, to Philadelphia (where one of the brothers coerced her to have two children by him) and was ultimately freed and lived in Haiti. The bronze sculpture was created by the Haitian artists Woodly Caymitte.

A number of traces and memorial sites are visible in the city. Moreover, in May 2009, the Museum of Aquitaine opened the spaces dedicated to "Bordeaux in the 18th century, trans-Atlantic trading and slavery". This work, richly illustrated with original documents, contributes to disseminate the state of knowledge on this question, presenting above all the facts and their chronology.

The region of Bordeaux was also the land of several prominent abolitionists, as Montesquieu, Laffon de Ladébat and Elisée Reclus. Others were members of the Society of the Friends of the Blacks as the revolutionaries Boyer-Fonfrède, Gensonné, Guadet and Ducos.

Parks and gardens

 * Jardin public de Bordeaux, with inside the Jardin botanique de Bordeaux
 * Jardin botanique de la Bastide
 * Parc bordelais
 * Parc aux Angéliques
 * Jardin des Lumières
 * Parc Rivière
 * Parc Floral

Pont Jacques Chaban-Delmas

Europe's longest-span vertical-lift bridge, the Pont Jacques Chaban-Delmas, was opened in 2013 in Bordeaux, spanning the River Garonne. The central lift span is 117 m, weighs 4,600 tons and can be lifted vertically up to 53 m to let tall ships pass underneath. The €160 million bridge was inaugurated by President François Hollande and Mayor Alain Juppé on 16 March 2013. The bridge was named after the late Jacques Chaban-Delmas, who was a former Prime Minister and Mayor of Bordeaux.

Shopping

Bordeaux has many shopping options. In the heart of Bordeaux is Rue Sainte-Catherine. This pedestrian-only shopping street has 1.2 km of shops, restaurants and cafés; it is also one of the longest shopping streets in Europe. Rue Sainte-Catherine starts at Place de la Victoire and ends at Place de la Comédie by the Grand Théâtre. The shops become progressively more upmarket as one moves towards Place de la Comédie and the nearby Cours de l'Intendance is where one finds the more exclusive shops and boutiques.

Culture
Bordeaux is also the first city in France to have created, in the 1980s, an architecture exhibition and research centre, Arc en rêve. Bordeaux offers a large number of cinemas, theatres, and is the home of the Opéra national de Bordeaux. There are many music venues of varying capacity. The city also offers several festivals throughout the year. In October 2021, Bordeaux was shortlisted for the European Commission's 2022 European Capital of Smart Tourism award along with Copenhagen, Dublin, Florence, Ljubljana, Palma de Mallorca and Valencia.

Road
Bordeaux is an important road and motorway junction. The city is connected to Paris by the A10 motorway, with Lyon by the A89, with Toulouse by the A62, and with Spain by the A63. There is a 45 km ring road called the "Rocade" which is often very busy. Another ring road is under consideration.

Bordeaux has five road bridges that cross the Garonne, the Pont de pierre built in the 1820s and three modern bridges built after 1960: the Pont Saint Jean, just south of the Pont de pierre (both located downtown), the Pont d'Aquitaine, a suspension bridge downstream from downtown, and the Pont François Mitterrand, located upstream of downtown. These two bridges are part of the ring-road around Bordeaux. A fifth bridge, the Pont Jacques-Chaban-Delmas, was constructed in 2009–2012 and opened to traffic in March 2013. Located halfway between the Pont de pierre and the Pont d'Aquitaine and serving downtown rather than highway traffic, it is a vertical-lift bridge with a height in closed position comparable to that of Pont de pierre, and to the Pont d'Aquitaine when open. All five road bridges, including the two highway bridges, are open to cyclists and pedestrians as well. Another bridge, the Pont Jean-Jacques Bosc, is to be built in 2018.

Lacking any steep hills, Bordeaux is relatively friendly to cyclists. Cycle paths (separate from the roadways) exist on the highway bridges, along the riverfront, on the university campuses, and incidentally elsewhere in the city. Cycle lanes and bus lanes that explicitly allow cyclists exist on many of the city's boulevards. A paid bicycle-sharing system with automated stations was established in 2010.

Rail

The main railway station, Gare de Bordeaux Saint-Jean, near the center of the city, has 12 million passengers a year. It is served by the French national (SNCF) railway's high speed train, the TGV, that gets to Paris in two hours, with connections to major European centers such as Lille, Brussels, Amsterdam, Cologne, Geneva and London. The TGV also serves Toulouse and Irun (Spain) from Bordeaux. A regular train service is provided to Nantes, Nice, Marseille and Lyon. The Gare Saint-Jean is the major hub for regional trains (TER) operated by the SNCF to Arcachon, Limoges, Agen, Périgueux, Langon, Pau, Le Médoc, Angoulême and Bayonne.

Historically the train line used to terminate at a station on the right bank of the river Garonne near the Pont de Pierre, and passengers crossed the bridge to get into the city. Subsequently, a double-track steel railway bridge was constructed in the 1850s, by Gustave Eiffel, to bring trains across the river direct into Gare de Bordeaux Saint-Jean. The old station was later converted and in 2010 comprised a cinema and restaurants.

The two-track Eiffel bridge with a speed limit of 30 km/h became a bottleneck and a new bridge was built, opening in 2009. The new bridge has four tracks and allows trains to pass at 60 km/h. During the planning there was much lobbying by the Eiffel family and other supporters to preserve the old bridge as a footbridge across the Garonne, with possibly a museum to document the history of the bridge and Gustave Eiffel's contribution. The decision was taken to save the bridge, but by early 2010 no plans had been announced as to its future use. The bridge remains intact, but unused and without any means of access.

The LGV Sud Europe Atlantique became fully operational in July 2017, shortening the journey time from Bordeaux city to Paris to 2hrs 4mins.

Air

Bordeaux is served by Bordeaux–Mérignac Airport, located 8 km from the city centre in the suburban city of Mérignac.

Trams, buses and boats

Bordeaux has an important public transport system called Transports Bordeaux Métropole (TBM). This company is run by the Keolis group. The network consists of:
 * Four tram lines (A, B, C and D)
 * 75 bus routes, all connected to the tramway network (from 1 to 96)
 * 13 night bus routes (from 1 to 16)
 * An electric bus shuttle in the city centre
 * A boat shuttle on the Garonne river

This network is operated from 5 am to 2 am.

There had been several plans for a subway network to be set up, but they stalled for both geological and financial reasons. Work on the Tramway de Bordeaux system was started in the autumn of 2000, and services started in December 2003 connecting Bordeaux with its suburban areas. The tram system uses Alstom APS a form of ground-level power supply technology developed by French company Alstom and designed to preserve the aesthetic environment by eliminating overhead cables in the historic city. Conventional overhead cables are used outside the city. The system was controversial for its considerable cost of installation, maintenance and also for the numerous initial technical problems that paralysed the network. Many streets and squares along the tramway route became pedestrian areas, with limited access for cars.

The Bordeaux Tramway system reached the Mérignac airport on April 29th 2023 with the opening of a 5-km extension of Line A.

Taxis
There are more than 400 taxicabs in Bordeaux.

Public transportation statistics
The average amount of time people spend commuting with public transit in Bordeaux, for example to and from work, on a weekday is 51 min. 12.% of public transit riders, ride for more than 2 hours every day. The average amount of time people wait at a stop or station for public transit is 13 min, while 15.5% of riders wait for over 20 minutes on average every day. The average distance people usually ride in a single trip with public transit is 7 km, while 8% travel for over 12 km in a single direction.

Sport

The 41,458-capacity Nouveau Stade de Bordeaux is the largest stadium in Bordeaux. The stadium was opened in 2015 and replaced the Stade Chaban-Delmas, which was a venue for the FIFA World Cup in 1938 and 1998, as well as the 2007 Rugby World Cup. In the 1938 FIFA World Cup, it hosted a violent quarter-final known as the Battle of Bordeaux. The ground was formerly known as the Stade du Parc Lescure until 2001, when it was renamed in honour of the city's long-time mayor, Jacques Chaban-Delmas.

There are two major sport teams in Bordeaux, Girondins de Bordeaux is the football team, playing in Ligue 2, the second tier of French football. Union Bordeaux Bègles is a rugby team in the Top 14 in the Ligue Nationale de Rugby. Skateboarding, rollerblading, and BMX biking are activities enjoyed by many young inhabitants of the city. Bordeaux is home to a quay which runs along the Garonne river. On the quay there is a skate-park divided into three sections. One section is for Vert tricks, one for street style tricks, and one for little action sports athletes with easier features and softer materials. The skate-park is very well maintained by the municipality.

Other sports clubs include top flight ice hockey team Boxers de Bordeaux and third-tier basketball team JSA Bordeaux Basket

Bordeaux is also the home to one of the strongest cricket teams in France and are champions of the South West League.

There is a 250 m wooden velodrome, Vélodrome du Lac, in Bordeaux which hosts international cycling competition in the form of UCI Track Cycling World Cup events.

The 2015 Trophee Eric Bompard was in Bordeaux. But the Free Skate was cancelled in all of the divisions due to the Paris bombing(s) and aftermath. The Short Program occurred hours before the bombing. French skaters Chafik Besseghier (68.36) in tenth place, Romain Ponsart (62.86) in 11th. Mae-Berenice-Meite (46.82) in 11th and Laurine Lecavelier (46.53) in 12th. Vanessa James/Morgan Cipres (65.75) in second.

Between 1951 and 1955, an annual Formula 1 motor race was held on a 2.5-kilometre circuit which looped around the Esplanade des Quinconces and along the waterfront, attracting drivers such as Juan Manuel Fangio, Stirling Moss, Jean Behra and Maurice Trintignant.

Notable people

 * Ausonius (310–395), Roman poet and teacher of rhetoric
 * Jean Alaux (1786–1864), painter
 * Bertrand Andrieu (1761–1822), engraver
 * Jean Anouilh (1910–1987), dramatist
 * Lucien Arman (1811–1873), shipbuilder and politician
 * Yvonne Arnaud (1892–1958), pianist, singer and actress
 * Xavier Arnozan (1852–1928), physician
 * Floyd Ayité (born 1988), Togolese footballer
 * Jonathan Ayité (born 1985), Togolese footballer
 * Christine Barbe, winemaker
 * Jean-Baptiste Barrière (1707–1747), cellist, composer
 * Gérard Bayo (born 1936), writer and poet,
 * François Bigot (1703–1778), last "Intendant" of New France
 * Arnaud Binard (born 1971), actor and producer
 * Rosa Bonheur (1822–1899), animal painter and sculptor
 * Grégory Bourdy (born 1982), golfer
 * Samuel Boutal (born 1969), footballer
 * Edmond de Caillou (died c. February 1316) Gascon knight fighting in Scotland
 * Gérald Caussé, Presiding Bishop of The Church of Jesus Christ of Latter Day Saints
 * Leopold Chasseriau (1825–1891), planter
 * René Clément (1913–1996), actor, director, writer
 * Jean-René Cruchet (1875–1959), pathologist
 * José Cubero Sánchez (1964–1985), Spanish bullfighter
 * Boris Cyrulnik (born 1937), psychiatrist and psychoanalyst
 * Damia (1899–1978), singer and actress
 * Étienne Noël Damilaville (1723–1768), encyclopédiste
 * Lili Damita (1901–1994), actress
 * Frédéric Daquin, (born 1978), footballer
 * Danielle Darrieux (1917–2017), actress
 * Bernard Delvaille (1931–2006), poet, essayist
 * David Diop (1927–1960), poet
 * Jean-Francois Domergue, footballer
 * Eleanor of Aquitaine (1122–1204), duchess of Aquitaine, queen of France and queen of England
 * Jacques Ellul (1912–1994), sociologist, theologian, Christian anarchist
 * Jean Eustache (1938–1981), Nouvelle Vague director
 * Marie Fel (1713–1794), opera singer
 * Jean-Luc Fournet (1965), papyrologist
 * Pierre-Jean Garat (1762–1823), singer
 * Armand Gensonné (1758–1793), politician
 * Sébastien Gervais (born 1976), professional footballer
 * Stephen Girard (1750–1831), merchant, banker, and Philadelphia philanthropist
 * Jérôme Gnako (born 1968), footballer
 * Randolphe Gohi (born 1969), former professional footballer
 * Eugène Goossens (1867–1958), conductor, violinist
 * Anna Hamilton (1864–1935), doctor, superintendent of the Protestant Hospital at Bordeaux (1901–1934)
 * Adolphe Jacquies (c. 1798–1860), Canadian shopkeeper, printer, trade unionist, and newspaper publisher
 * Pierre Lacour (1745–1814), painter
 * Léopold Lafleurance (1865–1953), flautist
 * Joseph Henri Joachim Lainé (1767–1835), statesman
 * Sainte Jeanne de Lestonnac (1556–1640), Roman Catholic saint and foundress of the Sisters of the Company of Mary, Our Lady
 * Christophe Lestrade (born 1969), former professional footballer
 * André Lhote (1885–1962), cubist painter
 * Jeanne Henriette Louis, (1938), professor of North American civilization
 * Jean-Baptiste Lynch (1749–1835), politician
 * Lucenzo (born 1983), singer
 * Jean-Jacques Magendie (1766–1835), officer
 * François Magendie (1783–1855), physiologist
 * Bruno Marie-Rose (born 1965), athlete (sprinter)
 * Albert Marquet, (1875–1947), painter
 * François Mauriac (1885–1970), writer, Nobel laureate 1952
 * Benjamin Millepied (born 1977), dancer and choreographer
 * Édouard Molinaro (1928–2013), film director, screenwriter
 * Pierre Molinier (1900–1976), painter, photographer
 * Michel de Montaigne (1533–1592), essayist
 * Montesquieu (1689–1755), man of letters and political philosopher
 * Olivier Mony (1966–), writer and literary critic
 * Étienne Marie Antoine Champion de Nansouty (1768–1815), general
 * Elie Okobo, basketball player
 * Pierre Palmade (born 1968), actor and comedian
 * St. Paulinus of Nola (354–431), educator, religious figure
 * Émile Péreire (1800–1875), banker and industrialist
 * Sophie Pétronin (born 1945), aid worker and humanitarian
 * Albert Pitres (1848–1928), neurologist
 * Hippolyte Pradelles (1824–1913), naturalist painter
 * Georges Antoine Pons Rayet (1839–1906), astronomer, discoverer of the Wolf-Rayet stars, & founder of the Bordeaux Observatory
 * Odilon Redon (1840–1916), painter
 * Richard II of England (1367–1400), king
 * Pierre Rode (1774–1830), violinist
 * Olinde Rodrigues (1795–1851), mathematician, banker and social reformer
 * Marie-Sabine Roger (born 1957), writer
 * Eugenie Santa Coloma Sourget (1827–1895), composer, pianist and singer
 * Bernard Sarrette (1765–1858), conductor and music pedagogue
 * Jean-Jacques Sempé (1932–2022), cartoonist
 * Florent Serra (born 1981), tennis player
 * Alfred Smith, (1854–1932), painter
 * Soko (born 1985), singer
 * Philippe Sollers, (born 1936), writer
 * Wilfried Tekovi, (born 1989), Togolese footballer
 * Elie Vinet (1509–1587), historian and humanist of the Renaissance
 * Adam Siao Him Fa, (born 2001), professional figure skater

Twin towns – sister cities
Bordeaux is twinned with:

 * 🇮🇱 Ashdod, Israel, since 1984
 * 🇪🇸 Bilbao, Spain
 * 🇦🇿 Baku, Azerbaijan, since 1985
 * Bristol, United Kingdom, since 1947
 * 🇲🇦 Casablanca, Morocco, since 1988
 * 🇯🇵 Fukuoka, Japan, since 1982
 * 🇵🇱 Kraków, Poland, since 1993
 * 🇵🇪 Lima, Peru, since 1957
 * 🇺🇸 Los Angeles, California United States, since 1968
 * 🇪🇸 Madrid, Spain, since 1984
 * 🇩🇪 Munich, Germany, since 1964
 * Oran, Algeria, since 2003
 * Porto, Portugal, since 1978
 * 🇨🇦 Quebec City, Quebec Canada, since 1962
 * 🇵🇸 Ramallah, Palestine
 * 🇱🇻 Riga, Latvia
 * 🇷🇺 Saint Petersburg, Russia, since 1993
 * Wuhan, China, since 1998

Partnerships

 * 🇹🇷 Samsun, Turkey, since 2010

title: Bordeaux


text:
Puzzle Bobble

Puzzle Bobble, (パズルボブル) internationally known as Bust-A-Move, is a 1994 tile-matching puzzle arcade game developed and published by Taito. It is based on the 1986 arcade game Bubble Bobble, featuring characters and themes from that game. Its characteristically cute Japanese animation and music, along with its play mechanics and level designs, made it successful as an arcade title and spawned several sequels and ports to home gaming systems.

Gameplay
At the start of each round, the rectangular playing arena contains a prearranged pattern of colored "bubbles". At the bottom of the screen, the player controls a device called a "pointer", which aims and fires bubbles up the screen. The color of bubbles fired is randomly generated and chosen from the colors of bubbles still left on the screen.

The objective of the game is to clear all the bubbles from the arena without any bubble crossing the bottom line. Bubbles will fire automatically if the player remains idle. After clearing the arena, the next round begins with a new pattern of bubbles to clear. The game consists of 32 levels. The fired bubbles travel in straight lines (possibly bouncing off the sidewalls of the arena), stopping when they touch other bubbles or reach the top of the arena. If a bubble touches identically-colored bubbles, forming a group of three or more, those bubbles—as well as any bubbles hanging from them—are removed from the field of play, and points are awarded. After every few shots, the "ceiling" of the playing arena drops downwards slightly, along with all the bubbles stuck to it. The number of shots between each drop of the ceiling is influenced by the number of bubble colors remaining. The closer the bubbles get to the bottom of the screen, the faster the music plays and if they cross the line at the bottom then the game is over.

Release
Two different versions of the original game were released. Puzzle Bobble was originally released in Japan only in June 1994 by Taito, running on Taito B System hardware (with the preliminary title "Bubble Buster"). Then, 6 months later in December, the international Neo Geo version of Puzzle Bobble was released. It was almost identical aside from being in stereo and having some different sound effects and translated text.

Reception
In Japan, Game Machine listed the Neo Geo version of Puzzle Bobble on their February 15, 1995 issue as being the second most-popular arcade game at the time. It went on to become Japan's second highest-grossing arcade printed circuit board (PCB) software of 1995, below Virtua Fighter 2. In North America, RePlay reported the Neo Geo version of Puzzle Bobble to be the fourth most-popular arcade game in February 1995.

Reviewing the Super NES version, Mike Weigand of Electronic Gaming Monthly called it "a thoroughly enjoyable and incredibly addicting puzzle game". He considered the two player mode the highlight, but also said that the one player mode provides a solid challenge. GamePro gave it a generally negative review, saying it starts out fun but that ultimately lacks intricacy and longevity. They elaborated that in one player mode all the levels feel the same, and that two player matches are over too quickly to build up any excitement. They also criticized the lack of any 3D effects in the graphics. Next Generation reviewed the SNES version of the game and called it "addictive as hell".

A reviewer for Next Generation, while questioning the continued viability of the action puzzle genre, admitted that the game is "very simple and very addictive". He remarked that though the 3DO version makes no significant additions, none are called for by a game with such simple enjoyment. GamePro's brief review of the 3DO version commented that the game's controls are responsive, and they also praised visuals and music. Edge magazine ranked the game 73rd on their 100 Best Video Games in 2007. IGN rated the SNES version 54th in its Top 100 SNES Games.

Legacy
The simplicity of the concept has led to many clones, both commercial and otherwise. 1996's Snood replaced the bubbles with small creatures and has been successful in its own right. Worms Blast was Team 17's take on the concept. On September 24, 2000, British game publisher Empire Interactive released a similar game, Spin Jam, for the original PlayStation console. Mobile clones include Bubble Witch Saga and Bubble Shooter. Frozen Bubble is a free software clone. For Bubble Bobble's 35th anniversary, Taito launched Puzzle Bobble VR: Vacation Odyssey on the Oculus Quest and Oculus Quest 2, later coming to PlayStation 4 and PlayStation 5 as Puzzle Bobble 3D: Vacation Odyssey in 2021. ''

Puzzle Bobble Everybubble!
Puzzle Bobble Everybubble! was released on May 23, 2023 for Nintendo Switch. The game also comes with an extra mode called "Puzzle Bobble vs. Space Invaders", where up to four players can work together to erase bubble-encased invaders before they reach the player while only being able to aim straight up.

license: Creative Commons - Attribution Share-Alike - https://creativecommons.org/licenses/by-sa/4.0/

title: Puzzle Bobble


text:
Bone

A bone is a rigid organ that constitutes part of the skeleton in most vertebrate animals. Bones protect the various other organs of the body, produce red and white blood cells, store minerals, provide structure and support for the body, and enable mobility. Bones come in a variety of shapes and sizes and have complex internal and external structures. They are lightweight yet strong and hard and serve multiple functions.

Bone tissue (osseous tissue), which is also called bone in the uncountable sense of that word, is hard tissue, a type of specialised connective tissue. It has a honeycomb-like matrix internally, which helps to give the bone rigidity. Bone tissue is made up of different types of bone cells. Osteoblasts and osteocytes are involved in the formation and mineralisation  of bone; osteoclasts are involved in the resorption of bone tissue. Modified (flattened) osteoblasts become the lining cells that form a protective layer on the bone surface. The mineralised matrix of bone tissue has an organic component of mainly collagen called ossein and an inorganic component of bone mineral made up of various salts. Bone tissue is mineralized tissue of two types, cortical bone and cancellous bone. Other types of tissue found in bones include bone marrow, endosteum, periosteum, nerves, blood vessels and cartilage.

In the human body at birth, approximately 300 bones are present. Many of these fuse together during development, leaving a total of 206 separate bones in the adult, not counting numerous small sesamoid bones. The largest bone in the body is the femur or thigh-bone, and the smallest is the stapes in the middle ear.

The Greek word for bone is ὀστέον ("osteon"), hence the many terms that use it as a prefix—such as osteopathy. In anatomical terminology, including the Terminologia Anatomica international standard, the word for a bone is os (for example, os breve, os longum, os sesamoideum).

Structure
Bone is not uniformly solid, but consists of a flexible matrix (about 30%) and bound minerals (about 70%), which are intricately woven and continuously remodeled by a group of specialized bone cells. Their unique composition and design allows bones to be relatively hard and strong, while remaining lightweight.

Bone matrix is 90 to 95% composed of elastic collagen fibers, also known as ossein, and the remainder is ground substance. The elasticity of collagen improves fracture resistance. The matrix is hardened by the binding of inorganic mineral salt, calcium phosphate, in a chemical arrangement known as bone mineral, a form of calcium apatite. It is the mineralization that gives bones rigidity.

Bone is actively constructed and remodeled throughout life by special bone cells known as osteoblasts and osteoclasts. Within any single bone, the tissue is woven into two main patterns, known as cortical and cancellous bone, each with a different appearance and characteristics.

Cortex

The hard outer layer of bones is composed of cortical bone, which is also called compact bone as it is much denser than cancellous bone. It forms the hard exterior (cortex) of bones. The cortical bone gives bone its smooth, white, and solid appearance, and accounts for 80% of the total bone mass of an adult human skeleton. It facilitates bone's main functions—to support the whole body, to protect organs, to provide levers for movement, and to store and release chemical elements, mainly calcium. It consists of multiple microscopic columns, each called an osteon or Haversian system. Each column is multiple layers of osteoblasts and osteocytes around a central canal called the osteonic canal. Volkmann's canals at right angles connect the osteons together. The columns are metabolically active, and as bone is reabsorbed and created the nature and location of the cells within the osteon will change. Cortical bone is covered by a periosteum on its outer surface, and an endosteum on its inner surface. The endosteum is the boundary between the cortical bone and the cancellous bone. The primary anatomical and functional unit of cortical bone is the osteon.

Trabeculae

Cancellous bone or spongy bone, also known as trabecular bone, is the internal tissue of the skeletal bone and is an open cell porous network that follows the material properties of biofoams. Cancellous bone has a higher surface-area-to-volume ratio than cortical bone and it is less dense. This makes it weaker and more flexible. The greater surface area also makes it suitable for metabolic activities such as the exchange of calcium ions. Cancellous bone is typically found at the ends of long bones, near joints, and in the interior of vertebrae. Cancellous bone is highly vascular and often contains red bone marrow where hematopoiesis, the production of blood cells, occurs. The primary anatomical and functional unit of cancellous bone is the trabecula. The trabeculae are aligned towards the mechanical load distribution that a bone experiences within long bones such as the femur. As far as short bones are concerned, trabecular alignment has been studied in the vertebral pedicle. Thin formations of osteoblasts covered in endosteum create an irregular network of spaces, known as trabeculae. Within these spaces are bone marrow and hematopoietic stem cells that give rise to platelets, red blood cells and white blood cells. Trabecular marrow is composed of a network of rod- and plate-like elements that make the overall organ lighter and allow room for blood vessels and marrow. Trabecular bone accounts for the remaining 20% of total bone mass but has nearly ten times the surface area of compact bone.

The words cancellous and trabecular refer to the tiny lattice-shaped units (trabeculae) that form the tissue. It was first illustrated accurately in the engravings of Crisóstomo Martinez.

Marrow
Bone marrow, also known as myeloid tissue in red bone marrow, can be found in almost any bone that holds cancellous tissue. In newborns, all such bones are filled exclusively with red marrow or hematopoietic marrow, but as the child ages the hematopoietic fraction decreases in quantity and the fatty/ yellow fraction called marrow adipose tissue (MAT) increases in quantity. In adults, red marrow is mostly found in the bone marrow of the femur, the ribs, the vertebrae and pelvic bones.

Vascular supply
Bone receives about 10% of cardiac output. Blood enters the endosteum, flows through the marrow, and exits through small vessels in the cortex. In humans, blood oxygen tension in bone marrow is about 6.6%, compared to about 12% in arterial blood, and 5% in venous and capillary blood.

Cells

Bone is metabolically active tissue composed of several types of cells. These cells include osteoblasts, which are involved in the creation and mineralization of bone tissue, osteocytes, and osteoclasts, which are involved in the reabsorption of bone tissue. Osteoblasts and osteocytes are derived from osteoprogenitor cells, but osteoclasts are derived from the same cells that differentiate to form macrophages and monocytes. Within the marrow of the bone there are also hematopoietic stem cells. These cells give rise to other cells, including white blood cells, red blood cells, and platelets.

Osteoblast

Osteoblasts are mononucleate bone-forming cells. They are located on the surface of osteon seams and make a protein mixture known as osteoid, which mineralizes to become bone. The osteoid seam is a narrow region of a newly formed organic matrix, not yet mineralized, located on the surface of a bone. Osteoid is primarily composed of Type I collagen. Osteoblasts also manufacture hormones, such as prostaglandins, to act on the bone itself. The osteoblast creates and repairs new bone by actually building around itself. First, the osteoblast puts up collagen fibers. These collagen fibers are used as a framework for the osteoblasts' work. The osteoblast then deposits calcium phosphate which is hardened by hydroxide and bicarbonate ions. The brand-new bone created by the osteoblast is called osteoid. Once the osteoblast is finished working it is actually trapped inside the bone once it hardens. When the osteoblast becomes trapped, it becomes known as an osteocyte. Other osteoblasts remain on the top of the new bone and are used to protect the underlying bone, these become known as bone lining cells.

Osteocyte
Osteocytes are cells of mesenchymal origin and originate from osteoblasts that have migrated into and become trapped and surrounded by a bone matrix that they themselves produced. The spaces the cell body of osteocytes occupy within the mineralized collagen type I matrix are known as lacunae, while the osteocyte cell processes occupy channels called canaliculi. The many processes of osteocytes reach out to meet osteoblasts, osteoclasts, bone lining cells, and other osteocytes probably for the purposes of communication. Osteocytes remain in contact with other osteocytes in the bone through gap junctions—coupled cell processes which pass through the canalicular channels.

Osteoclast
Osteoclasts are very large multinucleate cells that are responsible for the breakdown of bones by the process of bone resorption. New bone is then formed by the osteoblasts. Bone is constantly remodeled by the resorption of osteoclasts and created by osteoblasts. Osteoclasts are large cells with multiple nuclei located on bone surfaces in what are called Howship's lacunae (or resorption pits). These lacunae are the result of surrounding bone tissue that has been reabsorbed. Because the osteoclasts are derived from a monocyte stem-cell lineage, they are equipped with phagocytic-like mechanisms similar to circulating macrophages. Osteoclasts mature and/or migrate to discrete bone surfaces. Upon arrival, active enzymes, such as tartrate-resistant acid phosphatase, are secreted against the mineral substrate. The reabsorption of bone by osteoclasts also plays a role in calcium homeostasis.

Composition
Bones consist of living cells (osteoblasts and osteocytes) embedded in a mineralized organic matrix. The primary inorganic component of human bone is hydroxyapatite, the dominant bone mineral, having the nominal composition of Ca10(PO4)6(OH)2. The organic components of this matrix consist mainly of type I collagen—"organic" referring to materials produced as a result of the human body—and inorganic components, which alongside the dominant hydroxyapatite phase, include other compounds of calcium and phosphate including salts. Approximately 30% of the acellular component of bone consists of organic matter, while roughly 70% by mass is attributed to the inorganic phase. The collagen fibers give bone its tensile strength, and the interspersed crystals of hydroxyapatite give bone its compressive strength. These effects are synergistic. The exact composition of the matrix may be subject to change over time due to nutrition and biomineralization, with the ratio of calcium to phosphate varying between 1.3 and 2.0 (per weight), and trace minerals such as magnesium, sodium, potassium and carbonate also be found.

Type I collagen composes 90–95% of the organic matrix, with the remainder of the matrix being a homogenous liquid called ground substance consisting of proteoglycans such as hyaluronic acid and chondroitin sulfate, as well as non-collagenous proteins such as osteocalcin, osteopontin or bone sialoprotein. Collagen consists of strands of repeating units, which give bone tensile strength, and are arranged in an overlapping fashion that prevents shear stress. The function of ground substance is not fully known. Two types of bone can be identified microscopically according to the arrangement of collagen: woven and lamellar.

 * Woven bone (also known as fibrous bone), which is characterized by a haphazard organization of collagen fibers and is mechanically weak.
 * Lamellar bone, which has a regular parallel alignment of collagen into sheets ("lamellae") and is mechanically strong.

Woven bone is produced when osteoblasts produce osteoid rapidly, which occurs initially in all fetal bones, but is later replaced by more resilient lamellar bone. In adults, woven bone is created after fractures or in Paget's disease. Woven bone is weaker, with a smaller number of randomly oriented collagen fibers, but forms quickly; it is for this appearance of the fibrous matrix that the bone is termed woven. It is soon replaced by lamellar bone, which is highly organized in concentric sheets with a much lower proportion of osteocytes to surrounding tissue. Lamellar bone, which makes its first appearance in humans in the fetus during the third trimester, is stronger and filled with many collagen fibers parallel to other fibers in the same layer (these parallel columns are called osteons). In cross-section, the fibers run in opposite directions in alternating layers, much like in plywood, assisting in the bone's ability to resist torsion forces. After a fracture, woven bone forms initially and is gradually replaced by lamellar bone during a process known as "bony substitution". Compared to woven bone, lamellar bone formation takes place more slowly. The orderly deposition of collagen fibers restricts the formation of osteoid to about 1 to 2 μm per day. Lamellar bone also requires a relatively flat surface to lay the collagen fibers in parallel or concentric layers.

Deposition
The extracellular matrix of bone is laid down by osteoblasts, which secrete both collagen and ground substance. These cells synthesise collagen alpha polypetpide chains and then secrete collagen molecules. The collagen molecules associate with their neighbors and crosslink via lysyl oxidase to form collagen fibrils. At this stage, they are not yet mineralized, and this zone of unmineralized collagen fibrils is called "osteoid". Around and inside collagen fibrils calcium and phosphate eventually precipitate within days to weeks becoming then fully mineralized bone with an overall carbonate substituted hydroxyapatite inorganic phase.

In order to mineralise the bone, the osteoblasts secrete alkaline phosphatase, some of which is carried by vesicles. This cleaves the inhibitory pyrophosphate and simultaneously generates free phosphate ions for mineralization, acting as the foci for calcium and phosphate deposition. Vesicles may initiate some of the early mineralization events by rupturing and acting as a centre for crystals to grow on. Bone mineral may be formed from globular and plate structures, and via initially amorphous phases.

Types

Five types of bones are found in the human body: long, short, flat, irregular, and sesamoid.
 * Skeletal system.svg bones are characterized by a shaft, the diaphysis, that is much longer than its width; and by an epiphysis, a rounded head at each end of the shaft. They are made up mostly of compact bone, with lesser amounts of marrow, located within the medullary cavity, and areas of spongy, cancellous bone at the ends of the bones. Most bones of the limbs, including those of the fingers and toes, are long bones. The exceptions are the eight carpal bones of the wrist, the seven articulating tarsal bones of the ankle and the sesamoid bone of the kneecap. Long bones such as the clavicle, that have a differently shaped shaft or ends are also called modified long bones.
 * Short bones are roughly cube-shaped, and have only a thin layer of compact bone surrounding a spongy interior. Short bones provide stability and support as well as some limited motion. The bones of the wrist and ankle are short bones.
 * Flat bones are thin and generally curved, with two parallel layers of compact bone sandwiching a layer of spongy bone. Most of the bones of the skull are flat bones, as is the sternum.
 * Sesamoid bones are bones embedded in tendons. Since they act to hold the tendon further away from the joint, the angle of the tendon is increased and thus the leverage of the muscle is increased. Examples of sesamoid bones are the patella and the pisiform.
 * Irregular bones do not fit into the above categories. They consist of thin layers of compact bone surrounding a spongy interior. As implied by the name, their shapes are irregular and complicated. Often this irregular shape is due to their many centers of ossification or because they contain bony sinuses. The bones of the spine, pelvis, and some bones of the skull are irregular bones. Examples include the ethmoid and sphenoid bones.

Terminology
In the study of anatomy, anatomists use a number of anatomical terms to describe the appearance, shape and function of bones. Other anatomical terms are also used to describe the location of bones. Like other anatomical terms, many of these derive from Latin and Greek. Some anatomists still use Latin to refer to bones. The term "osseous", and the prefix "osteo-", referring to things related to bone, are still used commonly today.

Some examples of terms used to describe bones include the term "foramen" to describe a hole through which something passes, and a "canal" or "meatus" to describe a tunnel-like structure. A protrusion from a bone can be called a number of terms, including a "condyle", "crest", "spine", "eminence", "tubercle" or "tuberosity", depending on the protrusion's shape and location. In general, long bones are said to have a "head", "neck", and "body".

When two bones join, they are said to "articulate". If the two bones have a fibrous connection and are relatively immobile, then the joint is called a "suture".

Development
The formation of bone is called ossification. During the fetal stage of development this occurs by two processes: intramembranous ossification and endochondral ossification. Intramembranous ossification involves the formation of bone from connective tissue whereas endochondral ossification involves the formation of bone from cartilage.

Intramembranous ossification mainly occurs during formation of the flat bones of the skull but also the mandible, maxilla, and clavicles; the bone is formed from connective tissue such as mesenchyme tissue rather than from cartilage. The process includes: the development of the ossification center, calcification, trabeculae formation and the development of the periosteum.

Endochondral ossification occurs in long bones and most other bones in the body; it involves the development of bone from cartilage. This process includes the development of a cartilage model, its growth and development, development of the primary and secondary ossification centers, and the formation of articular cartilage and the epiphyseal plates.

Endochondral ossification begins with points in the cartilage called "primary ossification centers". They mostly appear during fetal development, though a few short bones begin their primary ossification after birth. They are responsible for the formation of the diaphyses of long bones, short bones and certain parts of irregular bones. Secondary ossification occurs after birth and forms the epiphyses of long bones and the extremities of irregular and flat bones. The diaphysis and both epiphyses of a long bone are separated by a growing zone of cartilage (the epiphyseal plate). At skeletal maturity (18 to 25 years of age), all of the cartilage is replaced by bone, fusing the diaphysis and both epiphyses together (epiphyseal closure). In the upper limbs, only the diaphyses of the long bones and scapula are ossified. The epiphyses, carpal bones, coracoid process, medial border of the scapula, and acromion are still cartilaginous.

The following steps are followed in the conversion of cartilage to bone:
 * 1) Zone of reserve cartilage. This region, farthest from the marrow cavity, consists of typical hyaline cartilage that as yet shows no sign of transforming into bone.
 * 2) Zone of cell proliferation. A little closer to the marrow cavity, chondrocytes multiply and arrange themselves into longitudinal columns of flattened lacunae.
 * 3) Zone of cell hypertrophy. Next, the chondrocytes cease to divide and begin to hypertrophy (enlarge), much like they do in the primary ossification center of the fetus. The walls of the matrix between lacunae become very thin.
 * 4) Zone of calcification. Minerals are deposited in the matrix between the columns of lacunae and calcify the cartilage. These are not the permanent mineral deposits of bone, but only a temporary support for the cartilage that would otherwise soon be weakened by the breakdown of the enlarged lacunae.
 * 5) Zone of bone deposition. Within each column, the walls between the lacunae break down and the chondrocytes die. This converts each column into a longitudinal channel, which is immediately invaded by blood vessels and marrow from the marrow cavity. Osteoblasts line up along the walls of these channels and begin depositing concentric lamellae of matrix, while osteoclasts dissolve the temporarily calcified cartilage.

Functions
Bones have a variety of functions:

Mechanical
Bones serve a variety of mechanical functions. Together the bones in the body form the skeleton. They provide a frame to keep the body supported, and an attachment point for skeletal muscles, tendons, ligaments and joints, which function together to generate and transfer forces so that individual body parts or the whole body can be manipulated in three-dimensional space (the interaction between bone and muscle is studied in biomechanics).

Bones protect internal organs, such as the skull protecting the brain or the ribs protecting the heart and lungs. Because of the way that bone is formed, bone has a high compressive strength of about 170 MPa, poor tensile strength of 104–121 MPa, and a very low shear stress strength (51.6 MPa). This means that bone resists pushing (compressional) stress well, resist pulling (tensional) stress less well, but only poorly resists shear stress (such as due to torsional loads). While bone is essentially brittle, bone does have a significant degree of elasticity, contributed chiefly by collagen.

Mechanically, bones also have a special role in hearing. The ossicles are three small bones in the middle ear which are involved in sound transduction.

Synthetic
The cancellous part of bones contain bone marrow. Bone marrow produces blood cells in a process called hematopoiesis. Blood cells that are created in bone marrow include red blood cells, platelets and white blood cells. Progenitor cells such as the hematopoietic stem cell divide in a process called mitosis to produce precursor cells. These include precursors which eventually give rise to white blood cells, and erythroblasts which give rise to red blood cells. Unlike red and white blood cells, created by mitosis, platelets are shed from very large cells called megakaryocytes. This process of progressive differentiation occurs within the bone marrow. After the cells are matured, they enter the circulation. Every day, over 2.5 billion red blood cells and platelets, and 50–100 billion granulocytes are produced in this way.

As well as creating cells, bone marrow is also one of the major sites where defective or aged red blood cells are destroyed.

Metabolic

 * Mineral storage – bones act as reserves of minerals important for the body, most notably calcium and phosphorus.

Determined by the species, age, and the type of bone, bone cells make up to 15 percent of the bone. Growth factor storage—mineralized bone matrix stores important growth factors such as insulin-like growth factors, transforming growth factor, bone morphogenetic proteins and others.
 * Fat storage – marrow adipose tissue (MAT) acts as a storage reserve of fatty acids.
 * Acid-base balance – bone buffers the blood against excessive pH changes by absorbing or releasing alkaline salts.
 * Detoxification – bone tissues can also store heavy metals and other foreign elements, removing them from the blood and reducing their effects on other tissues. These can later be gradually released for excretion.
 * Endocrine organ – bone controls phosphate metabolism by releasing fibroblast growth factor 23 (FGF-23), which acts on kidneys to reduce phosphate reabsorption. Bone cells also release a hormone called osteocalcin, which contributes to the regulation of blood sugar (glucose) and fat deposition. Osteocalcin increases both the insulin secretion and sensitivity, in addition to boosting the number of insulin-producing cells and reducing stores of fat.
 * Calcium balance – the process of bone resorption by the osteoclasts releases stored calcium into the systemic circulation and is an important process in regulating calcium balance. As bone formation actively fixes circulating calcium in its mineral form, removing it from the bloodstream, resorption actively unfixes it thereby increasing circulating calcium levels. These processes occur in tandem at site-specific locations.

Remodeling
Bone is constantly being created and replaced in a process known as remodeling. This ongoing turnover of bone is a process of resorption followed by replacement of bone with little change in shape. This is accomplished through osteoblasts and osteoclasts. Cells are stimulated by a variety of signals, and together referred to as a remodeling unit. Approximately 10% of the skeletal mass of an adult is remodelled each year. The purpose of remodeling is to regulate calcium homeostasis, repair microdamaged bones from everyday stress, and to shape the skeleton during growth. Repeated stress, such as weight-bearing exercise or bone healing, results in the bone thickening at the points of maximum stress (Wolff's law). It has been hypothesized that this is a result of bone's piezoelectric properties, which cause bone to generate small electrical potentials under stress.

The action of osteoblasts and osteoclasts are controlled by a number of chemical enzymes that either promote or inhibit the activity of the bone remodeling cells, controlling the rate at which bone is made, destroyed, or changed in shape. The cells also use paracrine signalling to control the activity of each other. For example, the rate at which osteoclasts resorb bone is inhibited by calcitonin and osteoprotegerin. Calcitonin is produced by parafollicular cells in the thyroid gland, and can bind to receptors on osteoclasts to directly inhibit osteoclast activity. Osteoprotegerin is secreted by osteoblasts and is able to bind RANK-L, inhibiting osteoclast stimulation.

Osteoblasts can also be stimulated to increase bone mass through increased secretion of osteoid and by inhibiting the ability of osteoclasts to break down osseous tissue. Increased secretion of osteoid is stimulated by the secretion of growth hormone by the pituitary, thyroid hormone and the sex hormones (estrogens and androgens). These hormones also promote increased secretion of osteoprotegerin. Osteoblasts can also be induced to secrete a number of cytokines that promote reabsorption of bone by stimulating osteoclast activity and differentiation from progenitor cells. Vitamin D, parathyroid hormone and stimulation from osteocytes induce osteoblasts to increase secretion of RANK-ligand and interleukin 6, which cytokines then stimulate increased reabsorption of bone by osteoclasts. These same compounds also increase secretion of macrophage colony-stimulating factor by osteoblasts, which promotes the differentiation of progenitor cells into osteoclasts, and decrease secretion of osteoprotegerin.

Volume
Bone volume is determined by the rates of bone formation and bone resorption. Certain growth factors may work to locally alter bone formation by increasing osteoblast activity. Numerous bone-derived growth factors have been isolated and classified via bone cultures. These factors include insulin-like growth factors I and II, transforming growth factor-beta, fibroblast growth factor, platelet-derived growth factor, and bone morphogenetic proteins. Evidence suggests that bone cells produce growth factors for extracellular storage in the bone matrix. The release of these growth factors from the bone matrix could cause the proliferation of osteoblast precursors. Essentially, bone growth factors may act as potential determinants of local bone formation. Cancellous bone volume in postmenopausal osteoporosis may be determined by the relationship between the total bone forming surface and the percent of surface resorption.

Clinical significance
A number of diseases can affect bone, including arthritis, fractures, infections, osteoporosis and tumors. Conditions relating to bone can be managed by a variety of doctors, including rheumatologists for joints, and orthopedic surgeons, who may conduct surgery to fix broken bones. Other doctors, such as rehabilitation specialists may be involved in recovery, radiologists in interpreting the findings on imaging, and pathologists in investigating the cause of the disease, and family doctors may play a role in preventing complications of bone disease such as osteoporosis.

When a doctor sees a patient, a history and exam will be taken. Bones are then often imaged, called radiography. This might include ultrasound X-ray, CT scan, MRI scan and other imaging such as a Bone scan, which may be used to investigate cancer. Other tests such as a blood test for autoimmune markers may be taken, or a synovial fluid aspirate may be taken.

Fractures

In normal bone, fractures occur when there is significant force applied or repetitive trauma over a long time. Fractures can also occur when a bone is weakened, such as with osteoporosis, or when there is a structural problem, such as when the bone remodels excessively (such as Paget's disease) or is the site of the growth of cancer. Common fractures include wrist fractures and hip fractures, associated with osteoporosis, vertebral fractures associated with high-energy trauma and cancer, and fractures of long-bones. Not all fractures are painful. When serious, depending on the fractures type and location, complications may include flail chest, compartment syndromes or fat embolism. Compound fractures involve the bone's penetration through the skin. Some complex fractures can be treated by the use of bone grafting procedures that replace missing bone portions.

Fractures and their underlying causes can be investigated by X-rays, CT scans and MRIs. Fractures are described by their location and shape, and several classification systems exist, depending on the location of the fracture. A common long bone fracture in children is a Salter–Harris fracture. When fractures are managed, pain relief is often given, and the fractured area is often immobilised. This is to promote bone healing. In addition, surgical measures such as internal fixation may be used. Because of the immobilisation, people with fractures are often advised to undergo rehabilitation.

Tumors
Tumor that can affect bone in several ways. Examples of benign bone tumors include osteoma, osteoid osteoma, osteochondroma, osteoblastoma, enchondroma, giant-cell tumor of bone, and aneurysmal bone cyst.

Cancer
Cancer can arise in bone tissue, and bones are also a common site for other cancers to spread (metastasise) to. Cancers that arise in bone are called "primary" cancers, although such cancers are rare. Metastases within bone are "secondary" cancers, with the most common being breast cancer, lung cancer, prostate cancer, thyroid cancer, and kidney cancer. Secondary cancers that affect bone can either destroy bone (called a "lytic" cancer) or create bone (a "sclerotic" cancer). Cancers of the bone marrow inside the bone can also affect bone tissue, examples including leukemia and multiple myeloma. Bone may also be affected by cancers in other parts of the body. Cancers in other parts of the body may release parathyroid hormone or parathyroid hormone-related peptide. This increases bone reabsorption, and can lead to bone fractures.

Bone tissue that is destroyed or altered as a result of cancers is distorted, weakened, and more prone to fracture. This may lead to compression of the spinal cord, destruction of the marrow resulting in bruising, bleeding and immunosuppression, and is one cause of bone pain. If the cancer is metastatic, then there might be other symptoms depending on the site of the original cancer. Some bone cancers can also be felt.

Cancers of the bone are managed according to their type, their stage, prognosis, and what symptoms they cause. Many primary cancers of bone are treated with radiotherapy. Cancers of bone marrow may be treated with chemotherapy, and other forms of targeted therapy such as immunotherapy may be used. Palliative care, which focuses on maximising a person's quality of life, may play a role in management, particularly if the likelihood of survival within five years is poor.

Other painful conditions

 * Osteomyelitis is inflammation of the bone or bone marrow due to bacterial infection.
 * Osteomalacia is a painful softening of adult bone caused by severe vitamin D deficiency.
 * Osteogenesis imperfecta
 * Osteochondritis dissecans
 * Ankylosing spondylitis
 * Skeletal fluorosis is a bone disease caused by an excessive accumulation of fluoride in the bones. In advanced cases, skeletal fluorosis damages bones and joints and is painful.

Osteoporosis
Osteoporosis is a disease of bone where there is reduced bone mineral density, increasing the likelihood of fractures. Osteoporosis is defined in women by the World Health Organization as a bone mineral density of 2.5 standard deviations below peak bone mass, relative to the age and sex-matched average. This density is measured using dual energy X-ray absorptiometry (DEXA), with the term "established osteoporosis" including the presence of a fragility fracture. Osteoporosis is most common in women after menopause, when it is called "postmenopausal osteoporosis", but may develop in men and premenopausal women in the presence of particular hormonal disorders and other chronic diseases or as a result of smoking and medications, specifically glucocorticoids. Osteoporosis usually has no symptoms until a fracture occurs. For this reason, DEXA scans are often done in people with one or more risk factors, who have developed osteoporosis and are at risk of fracture.

One of the most important risk factors for osteoporosis is advanced age. Accumulation of oxidative DNA damage in osteoblastic and osteoclastic cells appears to be a key factor in age-related osteoporosis.

Osteoporosis treatment includes advice to stop smoking, decrease alcohol consumption, exercise regularly, and have a healthy diet. Calcium and trace mineral supplements may also be advised, as may Vitamin D. When medication is used, it may include bisphosphonates, Strontium ranelate, and hormone replacement therapy.

Osteopathic medicine
Osteopathic medicine is a school of medical thought that links the musculoskeletal system to overall health. , over 77,000 physicians in the United States are trained in osteopathic medical schools.

Osteology
The study of bones and teeth is referred to as osteology. It is frequently used in anthropology, archeology and forensic science for a variety of tasks. This can include determining the nutritional, health, age or injury status of the individual the bones were taken from. Preparing fleshed bones for these types of studies can involve the process of maceration.

Typically anthropologists and archeologists study bone tools made by Homo sapiens and Homo neanderthalensis. Bones can serve a number of uses such as projectile points or artistic pigments, and can also be made from external bones such as antlers.

Other animals
Bird skeletons are very lightweight. Their bones are smaller and thinner, to aid flight. Among mammals, bats come closest to birds in terms of bone density, suggesting that small dense bones are a flight adaptation. Many bird bones have little marrow due to them being hollow.

A bird's beak is primarily made of bone as projections of the mandibles which are covered in keratin.

Some bones, primarily formed separately in subcutaneous tissues, include headgears (such as bony core of horns, antlers, ossicones), osteoderm, and os penis/os clitoris. A deer's antlers are composed of bone which is an unusual example of bone being outside the skin of the animal once the velvet is shed.

The extinct predatory fish Dunkleosteus had sharp edges of hard exposed bone along its jaws.

The proportion of cortical bone that is 80% in the human skeleton may be much lower in other animals, especially in marine mammals and marine turtles, or in various Mesozoic marine reptiles, such as ichthyosaurs, among others. This proportion can vary quickly in evolution; it often increases in early stages of returns to an aquatic lifestyle, as seen in early whales and pinnipeds, among others. It subsequently decreases in pelagic taxa, which typically acquire spongy bone, but aquatic taxa that live in shallow water can retain very thick, pachyostotic, osteosclerotic, or pachyosteosclerotic bones, especially if they move slowly, like sea cows. In some cases, even marine taxa that had acquired spongy bone can revert to thicker, compact bones if they become adapted to live in shallow water, or in hypersaline (denser) water.

Many animals, particularly herbivores, practice osteophagy—the eating of bones. This is presumably carried out in order to replenish lacking phosphate.

Many bone diseases that affect humans also affect other vertebrates—an example of one disorder is skeletal fluorosis.

Society and culture
Bones from slaughtered animals have a number of uses. In prehistoric times, they have been used for making bone tools. They have further been used in bone carving, already important in prehistoric art, and also in modern time as crafting materials for buttons, beads, handles, bobbins, calculation aids, head nuts, dice, poker chips, pick-up sticks, arrows, scrimshaw, ornaments, etc.

Bone glue can be made by prolonged boiling of ground or cracked bones, followed by filtering and evaporation to thicken the resulting fluid. Historically once important, bone glue and other animal glues today have only a few specialized uses, such as in antiques restoration. Essentially the same process, with further refinement, thickening and drying, is used to make gelatin.

Broth is made by simmering several ingredients for a long time, traditionally including bones.

Bone char, a porous, black, granular material primarily used for filtration and also as a black pigment, is produced by charring mammal bones.

Oracle bone script was a writing system used in Ancient China based on inscriptions in bones. Its name originates from oracle bones, which were mainly ox clavicle. The Ancient Chinese (mainly in the Shang dynasty), would write their questions on the oracle bone, and burn the bone, and where the bone cracked would be the answer for the questions.

To point the bone at someone is considered bad luck in some cultures, such as Australian aborigines, such as by the Kurdaitcha.

The wishbones of fowl have been used for divination, and are still customarily used in a tradition to determine which one of two people pulling on either prong of the bone may make a wish.

Various cultures throughout history have adopted the custom of shaping an infant's head by the practice of artificial cranial deformation. A widely practised custom in China was that of foot binding to limit the normal growth of the foot.

title: Bone