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Alameda, California

Alameda (Spanish for "tree-lined path") is a city in Alameda County, California, United States, located in the East Bay region of the Bay Area. The city is built on an informal archipelago in San Francisco Bay, consisting of Alameda Island, Bay Farm Island and Coast Guard Island, along with other smaller islands. As of the 2020 census, the city's population was 78,280.

Spanish and Mexican era
Alameda occupies what was originally a peninsula connected to Oakland. Much of it was low-lying and marshy. The higher ground nearby and adjacent parts of what is now downtown Oakland were the site of one of the largest coastal oak forests in the world. Spanish colonists called the area Encinal, meaning "forest of evergreen oak". Alameda is Spanish for "grove of poplar trees" or "tree-lined avenue". It was chosen as the name of the city in 1853 by popular vote.

The inhabitants at the time of the arrival of the Spanish in the late 18th century were a local band of the Ohlone tribe. The peninsula was included in the vast Rancho San Antonio granted in 1820 to Luis Peralta by the Spanish king who claimed California. The grant was later confirmed by the Republic of Mexico upon its independence in 1821 from Spain.

Over time, the place became known as Bolsa de Encinal or Encinal de San Antonio.

Post-Conquest era
The city was founded on June 6, 1853, after the United States acquired California following the Mexican–American War of 1848. The town originally contained three small settlements. "Alameda" referred to the village at Encinal and High streets, Hibbardsville was located at the North Shore ferry and shipping terminal, and Woodstock was on the west near the ferry piers of the South Pacific Coast Railroad and the Central Pacific. Eventually, the Central Pacific's ferry pier became the Alameda Mole. The borders of Alameda were made coextensive with the island in 1872, incorporating Woodstock into Alameda. In his autobiography, writer Mark Twain described Alameda as "The Garden of California." The first post office opened in 1854. The first school, Schermerhorn School, was opened in 1855 (and eventually renamed as Lincoln School). The San Francisco and Alameda Railroad opened the Encinal station in 1864. The early formation of the Park Street Historic Commercial District (or downtown) was centered near the train lines. Encinal's own post office opened in 1876, was renamed West End in 1877, and closed in 1891. On September 6, 1869, the Alameda Terminal made history; it was the site of the arrival of the first train via the First transcontinental railroad to reach the shores of San Francisco Bay, thus achieving the first coast to coast transcontinental railroad in North America.

The Croll Building, on the corner of Webster Street and Central Avenue, was the site of Croll's Gardens and Hotel, used as training quarters for some of the most popular fighters in boxing from 1883 to 1914. Jack Johnson and several other champions all stayed and trained here. ]

The need for expanded shipping facilities and increased flow of current through the estuary led to the dredging of a tidal canal through the marshland between Oakland and Alameda. Construction started in 1874, but it was not completed until 1902, resulting in Alameda becoming an island.

Modern era
In 1917, a private entertainment park called Neptune Beach was built in the area now known as Crab Cove, which became a major recreation destination in the 1920s and 1930s. Both the American snow cone and the popsicle were first sold at Neptune Beach. The Kewpie doll became the original prize for winning games of chance at the beach – another Neptune Beach innovation. The park closed down in 1939.

The Alameda Works Shipyard was one of the largest and best-equipped shipyards in the country. Together with other industrial facilities, it became part of the defense industry buildup before and during World War II, which attracted many migrants from other parts of the United States for the high-paying jobs. In the 1950s, Alameda's industrial and shipbuilding industries thrived along the Alameda Estuary.

In the early 21st century, the Port of Oakland, across the estuary, has become one of the largest ports on the West Coast. Its operators use shipping technologies originally experimented within Alameda. As of March 21, 2006, Alameda is a "Coast Guard City", one of seven then designated in the country. As of 2018, it is one of twenty-one within the country. In addition to the regular trains running to the Alameda Mole, Alameda was also served by local steam commuter lines of the Southern Pacific (initially, the Central Pacific). Alameda was the site of the Southern Pacific's West Alameda Shops, where all the electric trains were maintained and repaired. These were later adapted as the East Bay Electric Lines. The trains ran to both the Oakland Mole and the Alameda Mole.

In the 1930s Pan American Airways established a seaplane port along with the fill that led to the Alameda Mole, the original home base for the China Clipper flying boat. In 1929, the University of California established the San Francisco Airdrome located near the current Webster Street tube as a public airport. The Bay Airdrome had its gala christening party in 1930. The Airdrome was closed in 1941 when its air traffic interfered with the newly built Naval Air Station Alameda (NAS Alameda).

In the late 1950s, the Utah Construction Company began a landfill beyond the Old Sea Wall and created South Shore.

On February 7, 1973, a USN Vought A-7E Corsair II fighter jet on a routine training mission from Lemoore Naval Air Station suddenly caught fire 28,000 ft above the San Francisco Bay, crashing into the Tahoe Apartments in Alameda. Eleven people including the pilot died in the crash and fire.

Geography
Alameda's nickname is "The Island City" (or simply "the island"). The current city occupies three islands as well as a small section of the mainland. Today, the city consists of the main original section, with the former Naval Air Station Alameda (NAS Alameda) at the west end of Alameda Island, Southshore along the southern side of Alameda Island, and Bay Farm Island, which is part of the mainland proper.

The area of the former NAS is now known as "Alameda Point." The Southshore area is separated from the main part of Alameda Island by a lagoon; the north shore of the lagoon is located approximately where the original south shore of the island was. Alameda Point and Southshore are built on bay fill. Not all of Alameda Island is part of the City of Alameda; a small portion of a dump site west of the former runway at Alameda Naval Air Station extends far enough into San Francisco Bay that it is over the county line and therefore part of the City and County of San Francisco.

Coast Guard Island, a small island between Alameda Island and Oakland, is also part of Alameda and is the home of Integrated Support Command Alameda.

Ballena Isle, an even smaller island, is also part of Alameda.

Climate
This region experiences warm (but not hot), dry summers, and cool (but not cold), wet winters. According to the Köppen climate classification system, Alameda has a warm-summer Mediterranean climate, abbreviated "Csb" on climate maps. Annual precipitation is about 22. in, all rain (snow is extremely rare at sea level in the San Francisco Bay Area).

Hazards
The low-lying island has seen sea-level and groundwater level rise threaten its infrastructure and people not just through flooding events, but through the increased liquefaction risk from more saturated soils. The locations of increasing groundwater-induced risks and flooding risks (such as from another megaflood) may be most precise in private insurance company maps.

2010
The 2010 United States Census reported that Alameda had a population of 73,812. (2015 census estimates place the population at 78,630)

The population density was 3,214.9 PD/sqmi. The racial makeup of Alameda was 37,460 (50.8%) White, 23,058 (31.2%) Asian, 4,759 (6.4%) African American, 426 (0.6%) Native American, 381 (0.5%) Pacific Islander, 2,463 (3.3%) from other races, and 5,265 (7.1%) from two or more races. Hispanic or Latino of any race were 8,092 persons (11.0%).

The Census reported that 72,316 people (98.0% of the population) lived in households, 857 (1.2%) lived in non-institutionalized group quarters, and 639 (0.9%) were institutionalized.

There were 30,123 households, out of which 9,144 (30.4%) had children under the age of 18 living in them, 13,440 (44.6%) were opposite-sex married couples living together, 3,623 (12.0%) had a female householder with no husband present, 1,228 (4.1%) had a male householder with no wife present. There were 1,681 (5.6%) unmarried opposite-sex partnerships, and 459 (1.5%) same-sex married couples or same-sex partnerships. 9,347 households (31.0%) were made up of individuals, and 2,874 (9.5%) had someone living alone who was 65 years of age or older. The average household size was 2.40. There were 18,291 families (60.7% of all households); the average family size was 3.06.

The age distribution of the population shows 15,304 people (20.7%) under the age of 18, 5,489 people (7.4%) aged 18 to 24, 21,000 people (28.5%) aged 25 to 44, 22,044 people (29.9%) aged 45 to 64, and 9,975 people (13.5%) who were 65 years of age or older. The median age was 40.7 years. For every 100 females, there were 91.7 males. For every 100 females age 18 and over, there were 88.5 males.

Per capita annual income (in 2013 dollars) in 2009–2013 was $41,340 per the US Census. Median household income in 2009–2013 was $74,606 per the US Census.

There were 32,351 housing units at an average density of 1,409.0 /sqmi, of which 30,123 were occupied, of which 14,488 (48.1%) were owner-occupied, and 15,635 (51.9%) were occupied by renters. The homeowner vacancy rate was 1.1%; the rental vacancy rate was 5.7%. 37,042 people (50.2% of the population) lived in owner-occupied housing units and 35,274 people (47.8%) lived in rental housing units.

2000
As of the census of 2000, there were 72,259 people, 30,226 households, and 17,863 families residing in the city. The population density was 2,583.3/km$2$ (6,693.4/mi2). There were 31,644 housing units at an average density of 1,131.3/km$2$ (2,931.2/mi2). The racial makeup of the city was 56.95% White, 6.21% Black or African American, 0.67% Native American, 26.15% Asian, 0.60% Pacific Islander, 3.29% from other races, and 6.13% from two or more races. 9.31% of the population were Hispanic or Latino of any race.

There were 30,226 households, out of which 27.7% had children under the age of 18 living with them, 43.7% were married couples living together, 11.4% had a female householder with no husband present, and 40.9% were non-families. Of all households, 32.2% were made up of individuals, and 9.4% had someone living alone who was 65 years of age or older. The average household size was 2.35 and the average family size was 3.04.

In the city, the age distribution of the population shows 21.5% under the age of 18, 7.0% from 18 to 24, 33.6% from 25 to 44, 24.6% from 45 to 64, and 13.3% who were 65 years of age or older. The median age was 38 years. For every 100 females, there were 92.3 males. For every 100 females age 18 and over, there were 89.5 males.

The median income for a household in the city was $56,285, and the median income for a family was $68,625. Males had a median income of $49,174 versus $40,165 for females. The per capita income for the city was $30,982. About 6.0% of families and 8.2% of the population were below the poverty line, including 11.4% of those under age 18 and 6.1% of those age 65 or over.

There is a large Filipino community; and also a major Portuguese community, from which Tom Hanks' mother came and where Lyndsy Fonseca was raised for some time. Alameda also has a historic Japanese American community and had a small Japanese business district on a portion of Park Street before World War II, when the city's Japanese population was interned. A Japanese Buddhist church is one of the few remaining buildings left of Alameda's pre-war Japanese American community.

Economy
Naval Air Station Alameda (NAS), decommissioned in 1997, was turned over to the City of Alameda for civilian development, today known as Alameda Point.

The aircraft carrier USS Hornet (CV-12), a museum ship, has been moored at the former Naval Air Station as the USS Hornet Museum since 1998.

A cluster of artisan distilleries, wineries, breweries and tasting rooms along Monarch Street at Alameda Point is now referred to by the City of Alameda as "Spirits Alley". Admiral Maltings also sits in this area, supplying craft brewers and whisky producers, and is the first craft malting house in California.

According to the city's 2020 Comprehensive Annual Financial Report, the top employers in the city are:
 * Top employers

Arts and culture

The Alameda Arts Council (AAC) serves as the local Alameda City arts council. The Alameda Civic Ballet is the ballet troupe of the city. The Alameda Museum features displays on the history of Alameda. The Alameda Art Association has about 80 members as of January 2011, and has a gallery space at South Shore Center mall. The Association began in 1944. Photo-realist Robert Bechtle has painted numerous Alameda subjects, including Alameda Gran Torino, which was acquired by SFMOMA in 1974 and remains one of Bechtle's most famous works.

Theaters
The city restored the historic Art Deco city landmark Alameda Theatre, expanding it to include a theater multiplex. The public opening was May 21, 2008.

The Altarena Playhouse, which performs comedies, dramas, and musicals, was founded in 1938 and is the longest continuously operating community theater in the San Francisco Bay Area.

Festivals
The Fourth of July parade is advertised as the second oldest and second-longest Fourth of July parade in the United States. It features homemade floats, classic cars, motorized living room furniture, fire-breathing dragons, and marching bands.

There are three major events when the street in Alameda's historic downtown district is closed to vehicular traffic. The Park Street Spring Festival takes place every May during the weekend of Mother's Day and attracts over 50,000 visitors. The Park Street Art & Wine Faire takes place the last weekend of every July and attracts over 100,000 visitors. The Park Street Classic Car Show is held on the second Saturday every October and displays over 400 vintage vehicles.

The annual Sand Castle and Sculpture Contest takes place in June at the Robert Crown Memorial State Beach. The first contest was held in 1967.

Government
According to the California Secretary of State, as of February 10, 2019, Alameda has 48,609 registered voters. Of those, 27,323 (56.2%) are registered Democrats, 5,240 (10.8%) are registered Republicans, and 13,950 (28.7%) have declined to state a political party.

Alameda Free Library
After two previous failures, voters in the city passed a ballot measure in 2000 authorizing a bond measure for construction of a new main library to replace the city's Carnegie Library, damaged during the 1989 Loma Prieta earthquake. The city also received state funds for the new main library and opened the doors to the new facility in November 2006.

There are three library locations: the Main Library in downtown Alameda and two library branches; the Bay Farm Island Library serving the Bay Farm and Harbor Bay communities and the West End Library serving the West End of Alameda.

Education

Public primary and secondary education in Alameda is the responsibility of the Alameda Unified School District, which is legally separate from the City of Alameda government (as is common throughout California). The College of Alameda, a two-year community college in the West End is part of the Peralta Community College District. The city has numerous private primary schools, and one private high school, St. Joseph Notre Dame High School, a Catholic school.

Media
Alameda's first newspaper, the Encinal, appeared in the early 1850s. Following the Encinal, several other papers appeared along geographic lines, and the Daily Argus eventually rose to prominence. Around 1900, the Daily Argus began to fade in importance and east and west papers The Times and The Star combined to take the leading role as the Alameda Times-Star in the 1930s. The Times-Star was sold to the Alameda Newspaper Group in the 1970s. In 1997, the Hills Newspaper chain was bought by Knight Ridder. Between 2001 and 2023, the Alameda Sun ran a local weekly print newspaper.

The community is currently served by weekly newspaper, the Alameda Journal and a non-profit online news outlet called the Alameda Post.

Transportation

Vehicle access to Alameda Island is via three bridges from Oakland (Park Street, Fruitvale Avenue, and High Street Bridges), as well as the two one-way Posey and Webster Street Tubes leading into Oakland's Chinatown. Connections from Alameda to Bay Farm Island are provided via the Bay Farm Island Bridge for vehicular traffic as well as the Bay Farm Island Bicycle Bridge (the only pedestrian/bicycle-only drawbridge in the United States ).

California State Route 61 runs down city streets from the Posey and Webster Street Tubes, across the Bay Farm Island Bridge, and south to the Oakland Airport. The island is just minutes off Interstate 880 in Oakland. The speed limit for the city is 25 mph (40 km/h) on almost every road.

Public transportation options include:
 * AC Transit buses, which range from local connections to Oakland and Berkeley to express service to San Francisco
 * Ferry services – In addition to the Alameda/Oakland Ferry and the Alameda Harbor Bay Ferry routes, San Francisco Bay Ferry also provides service between Alameda Main Street Station and South San Francisco. All ferry services are operated by the Water Transit Authority.
 * The closest BART stations are Lake Merritt and 12th Street, near the exit to the Posey Tube, and Fruitvale, near the Fruitvale Bridge. BART's long-term plans for a second tunnel include Alameda as a candidate for the first stop on a new East Bay line.

Notable buildings

 * Alameda City Hall; NRHP-listed
 * Alameda High School; NRHP-listed
 * Croll Building; NRHP-listed and a California Historical Landmark
 * Masonic Temple and Lodge; NRHP-listed, and part of the Park Street Historic Commercial District
 * Park Street Historic Commercial District; NRHP-listed and a California Historical Landmark

Notable people

 * Albert Arents, a mining engineer who helped develop mineral resources of the Rocky Mountains.
 * John Baker, MLB catcher for San Diego Padres and Chicago Cubs, was born in Alameda.
 * Hester A. Benedict (1838–1921), president, Pacific Coast Women's Press Association
 * Mike Brisiel, an offensive guard for Oakland Raiders.
 * Virginia Lee Burton, Caldecott-winning children's author and illustrator.
 * Harold Camping, television and radio personality, president and general manager of Family Stations, Inc.
 * Phyllis Diller, television comedian, attended Sunday school at First Presbyterian, married and lived in Alameda at the start of her comedy act in San Francisco in the 1950s.
 * General James Doolittle, who received the Medal of Honor for his bombing of Japan during World War II; Doolittle was born in Alameda in 1896.
 * Garrett Eckbo, landscape architect who lived in Alameda as a child, later forming the Bay Area firm of Eckbo, Royston, Williams with Robert Royston and Edward Williams.
 * Leif Erickson, actor, born in Alameda in 1911.
 * Larry Eustachy, college basketball coach, born in Alameda.
 * Debbi Fields, founder of Mrs. Fields Cookies, attended Alameda High School, where she was a cheerleader.
 * Albert Ghiorso, nuclear scientist, co-discoverer of 12 chemical elements on the periodic table; in Guinness Book of World Records for Most Elements Discovered.
 * Brad Gillis, guitarist with Night Ranger, a San Francisco rock band formed in the 1980s.
 * Katharine Graham, the late publisher of The Washington Post, lived in Alameda as a child, according to Personal History, her autobiography.
 * Tim Hardaway Jr., a professional basketball player, was born in Alameda.
 * Horace Heidt, bandleader and radio personality, born in Alameda on May 21, 1901.
 * Emily Heller, comedian
 * Marielle Heller, actress and director
 * Bruce Henderson, author, grew up in Alameda, according to his book Hero Found: The Greatest POW Escape of the Vietnam War.
 * Benjamin Jealous, former President of the NAACP, lived in Alameda.
 * Joseph R. Knowland, congressman and Alameda native, was editor and publisher of the Oakland Tribune.
 * William Fife Knowland, U.S. Senator, was student body president at Alameda High School.
 * Robert L. Lippert, theater chain owner and film producer, was an Alameda native.
 * Paul Mantz, air racer and Hollywood stunt pilot, was born in Alameda in 1903.
 * Louis A. McCall Sr., drummer and musician known as the co-founder of Con Funk Shun.
 * Margaret McNamara, founder of Reading is Fundamental, and wife of Robert McNamara, grew up in Alameda.
 * George P. Miller, a congressman from 1945 to 1973.
 * Jack Mingo, author
 * Hugo Wilhelm Arthur Nahl, designer of the Seal of California.
 * Don Perata, former President Pro Tempore of California State Senate, lives in Alameda; once taught at Saint Joseph Notre Dame High, Encinal High, and Alameda High, among other Alameda schools.
 * Carl Ravazza, bandleader, born in Alameda, 1910.
 * Bill Rigney, Major League Baseball player and manager, was born in Alameda.
 * Dutch Ruether, pitcher for 1927 New York Yankees, was born in Alameda.
 * Jane Sibbett, actress and comedian, grew up in Alameda.
 * Operatic mezzo-soprano Frederica Von Stade has lived in Alameda since 1992.
 * Sharon Tate, actress, resident in early to late-1960s.
 * Charles Lee Tilden, for whom Tilden Regional Park is named, was a longtime resident of Alameda; Tilden Way at the southeast end of the city is named for him.
 * Baseball Hall of Famer Willie Stargell, MLB player Tommy Harper, MLB player Curtell Howard Motton, 2003 National League Rookie of the Year Dontrelle Willis, 2007 National League Most Valuable Player Jimmy Rollins, NBA player J.R. Rider, and NFL players Melvin Carver and Junior Tautalatasi  all attended Encinal High School.
 * Jason Kidd (NBA player and coach) and Joe Nelson (MLB pitcher) attended St. Joseph Notre Dame High School in Alameda.
 * MLB players Ray French, Johnny Vergez, Andy Carey, Bill Serena, Erik Schullstrom, Dick Bartell, Duffy Lewis, Chris Speier, and Bryan Woo all attended Alameda High School.
 * Many people from naval families, including celebrities such as Ann Curry, Brigette Lundy-Paine, Tom Hanks, and Jim Morrison of The Doors, have lived in Alameda.

Sister cities
Alameda's relationships with Wuxi and Jiangyin were initiated in 2005, in part, by Stewart Chen, who then served on the City of Alameda Social Service and Human Relations board, and who went on to be elected to Alameda City Council in November 2012.

Wuxi, China, is a so-called friendship city, because the diplomacy organization Sister Cities International does not recognize the relationship.

 * 🇨🇳 Jiangyin, China
 * 🇯🇵 Arita, Japan
 * 🇰🇷 Yeongdong-gun, South Korea
 * 🇸🇪 Lidingö, Sweden. Initiated in 1959 as part of President Eisenhower's people-to-people-movement, whose purpose was to develop better understanding among people from different countries after World War II. Both Alameda and Lidingö are islands with a bridge connecting them to a big city.
 * 🇵🇭 Dumaguete, Philippines
 * 🇮🇹 Varazze, Italy

Friendship city

 * 🇨🇳 Wuxi, China (Friendship city since 2004)

title: Alameda, California


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Alpha helix

An alpha helix (or α-helix) is a sequence of amino acids in a protein that are twisted into a coil (a helix).

The alpha helix is the most common structural arrangement in the secondary structure of proteins. It is also the most extreme type of local structure, and it is the local structure that is most easily predicted from a sequence of amino acids.

The alpha helix has a right-handed helix conformation in which every backbone N−H group hydrogen bonds to the backbone C=O group of the amino acid that is four residues earlier in the protein sequence.

Other names
The alpha helix is also commonly called a:
 * Pauling–Corey–Branson α-helix (from the names of three scientists who described its structure)
 * 3.613-helix because there are 3.6 amino acids in one ring, with 13 atoms being involved in the ring formed by the hydrogen bond (starting with amidic hydrogen and ending with carbonyl oxygen)

Discovery
In the early 1930s, William Astbury showed that there were drastic changes in the X-ray fiber diffraction of moist wool or hair fibers upon significant stretching. The data suggested that the unstretched fibers had a coiled molecular structure with a characteristic repeat of ≈5.1 Å.

Astbury initially proposed a linked-chain structure for the fibers. He later joined other researchers (notably the American chemist Maurice Huggins) in proposing that:

 * the unstretched protein molecules formed a helix (which he called the α-form)
 * the stretching caused the helix to uncoil, forming an extended state (which he called the β-form).

Although incorrect in their details, Astbury's models of these forms were correct in essence and correspond to modern elements of secondary structure, the α-helix and the β-strand (Astbury's nomenclature was kept), which were developed by Linus Pauling, Robert Corey and Herman Branson in 1951 (see below); that paper showed both right- and left-handed helices, although in 1960 the crystal structure of myoglobin showed that the right-handed form is the common one. Hans Neurath was the first to show that Astbury's models could not be correct in detail, because they involved clashes of atoms. Neurath's paper and Astbury's data inspired H. S. Taylor, Maurice Huggins and Bragg and collaborators to propose models of keratin that somewhat resemble the modern α-helix.

Two key developments in the modeling of the modern α-helix were: the correct bond geometry, thanks to the crystal structure determinations of amino acids and peptides and Pauling's prediction of planar peptide bonds; and his relinquishing of the assumption of an integral number of residues per turn of the helix. The pivotal moment came in the early spring of 1948, when Pauling caught a cold and went to bed. Being bored, he drew a polypeptide chain of roughly correct dimensions on a strip of paper and folded it into a helix, being careful to maintain the planar peptide bonds. After a few attempts, he produced a model with physically plausible hydrogen bonds. Pauling then worked with Corey and Branson to confirm his model before publication. In 1954, Pauling was awarded his first Nobel Prize "for his research into the nature of the chemical bond and its application to the elucidation of the structure of complex substances" (such as proteins), prominently including the structure of the α-helix.

Geometry and hydrogen bonding
The amino acids in an α-helix are arranged in a right-handed helical structure where each amino acid residue corresponds to a 100° turn in the helix (i.e., the helix has 3.6 residues per turn), and a translation of 1.5 Å along the helical axis. Dunitz describes how Pauling's first article on the theme in fact shows a left-handed helix, the enantiomer of the true structure. Short pieces of left-handed helix sometimes occur with a large content of achiral glycine amino acids, but are unfavorable for the other normal, biological L-amino acids. The pitch of the alpha-helix (the vertical distance between consecutive turns of the helix) is 5.4 Å, which is the product of 1.5 and 3.6. The most important thing is that the N-H group of one amino acid forms a hydrogen bond with the C=O group of the amino acid four residues earlier; this repeated i + 4 → i hydrogen bonding is the most prominent characteristic of an α-helix. Official international nomenclature specifies two ways of defining α-helices, rule 6.2 in terms of repeating φ, ψ torsion angles (see below) and rule 6.3 in terms of the combined pattern of pitch and hydrogen bonding. The α-helices can be identified in protein structure using several computational methods, such as DSSP (Define Secondary Structure of Protein).

Similar structures include the 310 helix (i + 3 → i hydrogen bonding) and the π-helix (i + 5 → i hydrogen bonding). The α-helix can be described as a 3.613 helix, since the i + 4 spacing adds three more atoms to the H-bonded loop compared to the tighter 310 helix, and on average, 3.6 amino acids are involved in one ring of α-helix. The subscripts refer to the number of atoms (including the hydrogen) in the closed loop formed by the hydrogen bond.

Residues in α-helices typically adopt backbone (φ, ψ) dihedral angles around (−60°, −45°), as shown in the image at right. In more general terms, they adopt dihedral angles such that the ψ dihedral angle of one residue and the φ dihedral angle of the next residue sum to roughly −105°. As a consequence, α-helical dihedral angles, in general, fall on a diagonal stripe on the Ramachandran diagram (of slope −1), ranging from (−90°, −15°) to (−70°, −35°). For comparison, the sum of the dihedral angles for a 310 helix is roughly −75°, whereas that for the π-helix is roughly −130°. The general formula for the rotation angle Ω per residue of any polypeptide helix with trans isomers is given by the equation

The α-helix is tightly packed; there is almost no free space within the helix. The amino-acid side-chains are on the outside of the helix, and point roughly "downward" (i.e., toward the N-terminus), like the branches of an evergreen tree (Christmas tree effect). This directionality is sometimes used in preliminary, low-resolution electron-density maps to determine the direction of the protein backbone.

Stability
Helices observed in proteins can range from four to over forty residues long, but a typical helix contains about ten amino acids (about three turns). In general, short polypeptides do not exhibit much α-helical structure in solution, since the entropic cost associated with the folding of the polypeptide chain is not compensated for by a sufficient amount of stabilizing interactions. In general, the backbone hydrogen bonds of α-helices are considered slightly weaker than those found in β-sheets, and are readily attacked by the ambient water molecules. However, in more hydrophobic environments such as the plasma membrane, or in the presence of co-solvents such as trifluoroethanol (TFE), or isolated from solvent in the gas phase, oligopeptides readily adopt stable α-helical structure. Furthermore, crosslinks can be incorporated into peptides to conformationally stabilize helical folds. Crosslinks stabilize the helical state by entropically destabilizing the unfolded state and by removing enthalpically stabilized "decoy" folds that compete with the fully helical state. It has been shown that α-helices are more stable, robust to mutations and designable than β-strands in natural proteins, and also in artificially designed proteins.

Visualization
The 3 most popular ways of visualizing the alpha-helical secondary structure of oligopeptide sequences are (1) a helical wheel, (2) a wenxiang diagram, and (3) a helical net. Each of these can be visualized with various software packages and web servers. To generate a small number of diagrams, Heliquest can be used for helical wheels, and NetWheels can be used for helical wheels and helical nets. To programmatically generate a large number of diagrams, helixvis can be used to draw helical wheels and wenxiang diagrams in the R and Python programming languages.

Experimental determination
Since the α-helix is defined by its hydrogen bonds and backbone conformation, the most detailed experimental evidence for α-helical structure comes from atomic-resolution X-ray crystallography such as the example shown at right. It is clear that all the backbone carbonyl oxygens point downward (toward the C-terminus) but splay out slightly, and the H-bonds are approximately parallel to the helix axis. Protein structures from NMR spectroscopy also show helices well, with characteristic observations of nuclear Overhauser effect (NOE) couplings between atoms on adjacent helical turns. In some cases, the individual hydrogen bonds can be observed directly as a small scalar coupling in NMR.

There are several lower-resolution methods for assigning general helical structure. The NMR chemical shifts (in particular of the Cα, Cβ and C′) and residual dipolar couplings are often characteristic of helices. The far-UV (170–250 nm) circular dichroism spectrum of helices is also idiosyncratic, exhibiting a pronounced double minimum at around 208 and 222 nm. Infrared spectroscopy is rarely used, since the α-helical spectrum resembles that of a random coil (although these might be discerned by, e.g., hydrogen-deuterium exchange). Finally, cryo electron microscopy is now capable of discerning individual α-helices within a protein, although their assignment to residues is still an active area of research.

Long homopolymers of amino acids often form helices if soluble. Such long, isolated helices can also be detected by other methods, such as dielectric relaxation, flow birefringence, and measurements of the diffusion constant. In stricter terms, these methods detect only the characteristic prolate (long cigar-like) hydrodynamic shape of a helix, or its large dipole moment.

Amino-acid propensities
Different amino-acid sequences have different propensities for forming α-helical structure. Methionine, alanine, leucine, glutamate, and lysine uncharged ("MALEK" in the amino-acid 1-letter codes) all have especially high helix-forming propensities, whereas proline and glycine have poor helix-forming propensities. Proline either breaks or kinks a helix, both because it cannot donate an amide hydrogen bond (having no amide hydrogen), and also because its sidechain interferes sterically with the backbone of the preceding turn – inside a helix, this forces a bend of about 30° in the helix's axis. However, proline is often seen as the first residue of a helix, it is presumed due to its structural rigidity. At the other extreme, glycine also tends to disrupt helices because its high conformational flexibility makes it entropically expensive to adopt the relatively constrained α-helical structure.

Table of standard amino acid alpha-helical propensities
Estimated differences in free energy change, Δ(ΔG), estimated in kcal/mol per residue in an α-helical configuration, relative to alanine arbitrarily set as zero. Higher numbers (more positive free energy changes) are less favoured. Significant deviations from these average numbers are possible, depending on the identities of the neighbouring residues.

 * {| class="wikitable sortable"

!rowspan=2| Amino acid !rowspan=2 class="unsortable"| 3- letter !rowspan=2 class="unsortable"| 1- letter !colspan=2| Helical penalty !kcal/mol !kJ/mol
 * +Differences in free energy change per residue
 * Alanine
 * Ala
 * A
 * 0.00 kcal/mol
 * Arginine
 * Arg
 * R
 * 0.21 kcal/mol
 * Asparagine
 * Asn
 * N
 * 0.65 kcal/mol
 * Aspartic acid
 * Asp
 * D
 * 0.69 kcal/mol
 * Cysteine
 * Cys
 * C
 * 0.68 kcal/mol
 * Glutamic acid
 * Glu
 * E
 * 0.40 kcal/mol
 * Glutamine
 * Gln
 * Q
 * 0.39 kcal/mol
 * Glycine
 * Gly
 * G
 * 1.00 kcal/mol
 * Histidine
 * His
 * H
 * 0.61 kcal/mol
 * Isoleucine
 * Ile
 * I
 * 0.41 kcal/mol
 * Leucine
 * Leu
 * L
 * 0.21 kcal/mol
 * Lysine
 * Lys
 * K
 * 0.26 kcal/mol
 * Methionine
 * Met
 * M
 * 0.24 kcal/mol
 * Phenylalanine
 * Phe
 * F
 * 0.54 kcal/mol
 * Proline
 * Pro
 * P
 * 3.16 kcal/mol
 * Serine
 * Ser
 * S
 * 0.50 kcal/mol
 * Threonine
 * Thr
 * T
 * 0.66 kcal/mol
 * Tryptophan
 * Trp
 * W
 * 0.49 kcal/mol
 * Tyrosine
 * Tyr
 * Y
 * 0.53 kcal/mol
 * Valine
 * Val
 * V
 * 0.61 kcal/mol
 * }
 * Threonine
 * Thr
 * T
 * 0.66 kcal/mol
 * Tryptophan
 * Trp
 * W
 * 0.49 kcal/mol
 * Tyrosine
 * Tyr
 * Y
 * 0.53 kcal/mol
 * Valine
 * Val
 * V
 * 0.61 kcal/mol
 * }
 * V
 * 0.61 kcal/mol
 * }

Dipole moment
A helix has an overall dipole moment due to the aggregate effect of the individual microdipoles from the carbonyl groups of the peptide bond pointing along the helix axis. The effects of this macrodipole are a matter of some controversy. α-helices often occur with the N-terminal end bound by a negatively charged group, sometimes an amino acid side chain such as glutamate or aspartate, or sometimes a phosphate ion. Some regard the helix macrodipole as interacting electrostatically with such groups. Others feel that this is misleading and it is more realistic to say that the hydrogen bond potential of the free NH groups at the N-terminus of an α-helix can be satisfied by hydrogen bonding; this can also be regarded as set of interactions between local microdipoles such as C=O···H−N.

Coiled coils
Coiled-coil α helices are highly stable forms in which two or more helices wrap around each other in a "supercoil" structure. Coiled coils contain a highly characteristic sequence motif known as a heptad repeat, in which the motif repeats itself every seven residues along the sequence (amino acid residues, not DNA base-pairs). The first and especially the fourth residues (known as the a and d positions) are almost always hydrophobic; the fourth residue is typically leucine – this gives rise to the name of the structural motif called a leucine zipper, which is a type of coiled-coil. These hydrophobic residues pack together in the interior of the helix bundle. In general, the fifth and seventh residues (the e and g positions) have opposing charges and form a salt bridge stabilized by electrostatic interactions. Fibrous proteins such as keratin or the "stalks" of myosin or kinesin often adopt coiled-coil structures, as do several dimerizing proteins. A pair of coiled-coils – a four-helix bundle –  is a very common structural motif in proteins. For example, it occurs in human growth hormone and several varieties of cytochrome. The Rop protein, which promotes plasmid replication in bacteria, is an interesting case in which a single polypeptide forms a coiled-coil and two monomers assemble to form a four-helix bundle.

Facial arrangements
The amino acids that make up a particular helix can be plotted on a helical wheel, a representation that illustrates the orientations of the constituent amino acids (see the article for leucine zipper for such a diagram). Often in globular proteins, as well as in specialized structures such as coiled-coils and leucine zippers, an α-helix will exhibit two "faces" – one containing predominantly hydrophobic amino acids oriented toward the interior of the protein, in the hydrophobic core, and one containing predominantly polar amino acids oriented toward the solvent-exposed surface of the protein.

Changes in binding orientation also occur for facially-organized oligopeptides. This pattern is especially common in antimicrobial peptides, and many models have been devised to describe how this relates to their function. Common to many of them is that the hydrophobic face of the antimicrobial peptide forms pores in the plasma membrane after associating with the fatty chains at the membrane core.

Larger-scale assemblies
Myoglobin and hemoglobin, the first two proteins whose structures were solved by X-ray crystallography, have very similar folds made up of about 70% α-helix, with the rest being non-repetitive regions, or "loops" that connect the helices. In classifying proteins by their dominant fold, the Structural Classification of Proteins database maintains a large category specifically for all-α proteins.

Hemoglobin then has an even larger-scale quaternary structure, in which the functional oxygen-binding molecule is made up of four subunits.

DNA binding
α-Helices have particular significance in DNA binding motifs, including helix-turn-helix motifs, leucine zipper motifs and zinc finger motifs. This is because of the convenient structural fact that the diameter of an α-helix is about 12 Å including an average set of sidechains, about the same as the width of the major groove in B-form DNA, and also because coiled-coil (or leucine zipper) dimers of helices can readily position a pair of interaction surfaces to contact the sort of symmetrical repeat common in double-helical DNA. An example of both aspects is the transcription factor Max (see image at left), which uses a helical coiled coil to dimerize, positioning another pair of helices for interaction in two successive turns of the DNA major groove.

Membrane spanning
α-Helices are also the most common protein structure element that crosses biological membranes (transmembrane protein), it is presumed because the helical structure can satisfy all backbone hydrogen-bonds internally, leaving no polar groups exposed to the membrane if the sidechains are hydrophobic. Proteins are sometimes anchored by a single membrane-spanning helix, sometimes by a pair, and sometimes by a helix bundle, most classically consisting of seven helices arranged up-and-down in a ring such as for rhodopsins (see image at right) and other G protein–coupled receptors (GPCRs). The structural stability between pairs of α-Helical transmembrane domains rely on conserved membrane interhelical packing motifs, for example, the Glycine-xxx-Glycine (or small-xxx-small) motif.

Mechanical properties
α-Helices under axial tensile deformation, a characteristic loading condition that appears in many alpha-helix-rich filaments and tissues, results in a characteristic three-phase behavior of stiff-soft-stiff tangent modulus. Phase I corresponds to the small-deformation regime during which the helix is stretched homogeneously, followed by phase II, in which alpha-helical turns break mediated by the rupture of groups of H-bonds. Phase III is typically associated with large-deformation covalent bond stretching.

Dynamical features
Alpha-helices in proteins may have low-frequency accordion-like motion as observed by the Raman spectroscopy and analyzed via the quasi-continuum model. Helices not stabilized by tertiary interactions show dynamic behavior, which can be mainly attributed to helix fraying from the ends.

Helix–coil transition
Homopolymers of amino acids (such as polylysine) can adopt α-helical structure at low temperature that is "melted out" at high temperatures. This helix–coil transition was once thought to be analogous to protein denaturation. The statistical mechanics of this transition can be modeled using an elegant transfer matrix method, characterized by two parameters: the propensity to initiate a helix and the propensity to extend a helix.

In art

At least five artists have made explicit reference to the α-helix in their work: Julie Newdoll in painting and Julian Voss-Andreae, Bathsheba Grossman, Byron Rubin, and Mike Tyka in sculpture.

San Francisco area artist Julie Newdoll, who holds a degree in microbiology with a minor in art, has specialized in paintings inspired by microscopic images and molecules since 1990. Her painting "Rise of the Alpha Helix" (2003) features human figures arranged in an α helical arrangement. According to the artist, "the flowers reflect the various types of sidechains that each amino acid holds out to the world". This same metaphor is also echoed from the scientist's side: "β sheets do not show a stiff repetitious regularity but flow in graceful, twisting curves, and even the α-helix is regular more in the manner of a flower stem, whose branching nodes show the influence of environment, developmental history, and the evolution of each part to match its own idiosyncratic function."

Julian Voss-Andreae is a German-born sculptor with degrees in experimental physics and sculpture. Since 2001 Voss-Andreae creates "protein sculptures" based on protein structure with the α-helix being one of his preferred objects. Voss-Andreae has made α-helix sculptures from diverse materials including bamboo and whole trees. A monument Voss-Andreae created in 2004 to celebrate the memory of Linus Pauling, the discoverer of the α-helix, is fashioned from a large steel beam rearranged in the structure of the α-helix. The 10 ft, bright-red sculpture stands in front of Pauling's childhood home in Portland, Oregon.

Ribbon diagrams of α-helices are a prominent element in the laser-etched crystal sculptures of protein structures created by artist Bathsheba Grossman, such as those of insulin, hemoglobin, and DNA polymerase. Byron Rubin is a former protein crystallographer now professional sculptor in metal of proteins, nucleic acids, and drug molecules – many of which featuring α-helices, such as subtilisin, human growth hormone, and phospholipase A2.

Mike Tyka is a computational biochemist at the University of Washington working with David Baker. Tyka has been making sculptures of protein molecules since 2010 from copper and steel, including ubiquitin and a potassium channel tetramer.

license: Creative Commons - Attribution Share-Alike - https://creativecommons.org/licenses/by-sa/4.0/

title: Alpha helix


text:
Accrington

Accrington is a town in the Hyndburn borough of Lancashire, England. It lies about 4 mi east of Blackburn, 6 mi west of Burnley, 13 mi east of Preston, 20 mi north of Manchester and is situated on the culverted River Hyndburn. Commonly abbreviated by locals to "Accy", the town has a population of 35,456 according to the 2011 census.

Accrington is a former centre of the cotton and textile machinery industries. The town is famed for manufacturing the hardest and densest building bricks in the world, "The Accrington NORI" (iron), which were used in the construction of the Empire State Building and for the foundations of Blackpool Tower; famous for Accrington Stanley F.C. and the Haworth Art Gallery which holds Europe's largest collection of Tiffany glass.

Etymology
The name "Accrington" likely has Anglo-Saxon origins. The earliest known recording of the name is found in the Parish of Whalley records from 850, where it is written as "Akeringastun". In subsequent records, the name appears in various forms, including "Akarinton" in 1194, "Akerunton", "Akerinton", and "Akerynton" in 1258, "Acrinton" in 1292, "Ackryngton" in 1311, and "Acryngton" in 1324. The name may derive from the Old English words "æcern", meaning "acorn", and "tun", meaning "farmstead" or "village", thus possibly meaning "acorn farmstead". However, some sources argue that this interpretation is not definitive and that alternative explanations may exist.

New Accrington, the southern part of the town, was historically part of the Forest of Blackburnshire. The area's abundance of oak trees can be inferred from local place names such as Broad Oak and Oak Hill. Acorns, a product of oak trees, were once a crucial food source for swine, which may have led to the naming of a farmstead after this resource. In the Lancashire dialect, "acorn" is pronounced "akran", which might have influenced the name's development.

No known Old English personal name corresponds to the first element in "Accrington". Nevertheless, the Frisian names "Akkrum" and "Akkeringa", as well as the Dutch name "Akkerghem", are believed to derive from the personal name "Akker". This finding suggests the possibility of a related Old English name from which "Accrington" could have originated. It is also worth noting that "Ingas" is the Old Norse word for "tribe", which may be relevant to the name's origin.

Overall, the etymology of "Accrington" is complex and there are several theories about its origin. While the "acorn farmstead" interpretation is the most commonly accepted explanation, further research and analysis may be needed to confirm or refute this theory, or to identify alternative possibilities.

Early history
There appears to be no mention of Accrington from the Roman period. The area typically appears to be heavily forested, with very few established settlements. According to folklore, a tall Danish tribal leader named Wada invaded the area between 760 and 798; who seems to have founded Waddington, Paddington (Padiham) and Akeringastun (Accrington). Descendants of the Wada held much of the lands until the sixteenth century. In 1442, the Waddingtons' hold leases on Berefeld (Bellfield), and in 1517 it is recorded that Thomas Waddington transferred the lands Scaytcliff (Scaitcliffe) and Peneworth (Pennyworth) to Nicholas Rishton and to his Son Geoffrey. Accrington covers two townships which were established in 1507 following disafforestation; those of Old Accrington and New Accrington; which were merged in 1878 with the incorporation of the borough council. The William Yates map of The county Palatine of Lancaster printed in 1786 shows Old Accrington included the area of Oaklea and also the intersection of the Winburn River (now the River Hyndburn) and Warmden Brook. New Accrington included the area of Green Haworth and Broadfield. There have been settlements there since the medieval period, likely in the Grange Lane and Black Abbey area, and the King's Highway which passes above the town was at one time used by the kings and queens of England when they used the area for hunting when the Forest of Accrington was one of the four forests of the hundred of Blackburnshire.

Robert de Lacy gave the manor of Accrington to the monks of Kirkstall in the 12th century. The monks built a grange there; removing the inhabitants to make room for it. The locals got their revenge by setting fire to the new building, destroying its contents and in the process killing the three lay brothers who occupied it. An area of the town is named 'Black Abbey', a possible reference to the murders. Regardless of whatever happened, Accrington did not remain under monastic control for long before reverting to the de Lacys.

It is thought the monks of Kirkstall may have built a small chapel there during their tenure for the convenience of those in charge residing there and their tenants, but the records are uncertain. What is known is that there was a chapel in Accrington prior to 1553 where the vicar of Whalley was responsible for the maintenance of divine worship. However it did not have its own minister and it was served, when at all, by the curate of one of the adjacent chapels. In 1717 Accrington was served by the curate of Church, who preached there only once a month. St. James's Church was built in 1763, replacing the old chapel however it did not achieve parochial status until as late as 1870.

Industrial Revolution
Until around 1830, visitors considered Accrington to be just a "considerable village". The Industrial Revolution, however, resulted in large changes and Accrington's location on the confluence of a number of streams made it attractive to industry and a number of mills were built in the town in the mid-18th century. Further industrialisation then followed in the late-18th century and local landowners began building mansions in the area on the outskirts of the settlement where their mills were located while their employees lived in overcrowded unsanitary conditions in the centre.

Industrialisation resulted in rapid population growth during the 19th century, as people moved from over North West England to Accrington, with the population increasing from 3,266 in 1811 to 10,376 in 1851 to 43,211 in 1901 to its peak in 1911 at 45,029.

This fast population growth and slow response from the established church allowed non-conformism to flourish in the town. By the mid-19th century, there were Wesleyan, Primitive Methodist, United Free Methodist, Congregationalist, Baptist, Swedenborgian, Unitarian, Roman Catholic and Catholic Apostolic churches in the town. The Swedenborgian church was so grand that it was considered to be the ‘Cathedral' of that denomination.

For many decades the textiles industry, the engineering industry and coal mining were the central activities of the town. Cotton mills and dye works provided work for the inhabitants, but often in very difficult conditions. There was a regular conflict with employers over wages and working conditions. On 24 April 1826 over 1,000 men and women, many armed, gathered at Whinney Hill in Clayton-le-Moors to listen to a speaker from where they marched on Sykes's Mill at Higher Grange Lane, near the site of the modern police station and magistrates' courts, and smashed over 60 looms. These riots spread from Accrington through Oswaldtwistle, Blackburn, Darwen, Rossendale, Bury and Chorley. In the end, after three days of riots 1,139 looms were destroyed, 4 rioters and 2 bystanders shot dead by the authorities in Rossendale and 41 rioters sentenced to death (all of whose sentences were commuted).

In 1842 'plug riots' a general strike spread from town to town due to conditions in the town. In a population of 9,000 people as few as 100 were fully employed. From 15 August 1842 the situation boiled over and bands of men entered the mills which were running and stopped the machinery by knocking out the boiler plugs. This allowed the water and steam to escape shutting down the mill machinery. Thousands of strikers walked over the hills from one town to another to persuade people to join the strike in civil disturbances that lasted about a week. The strike was associated with the Chartist movement but eventually proved unsuccessful in its aims.

In the early 1860s the Lancashire cotton famine badly affected Accrington, although less so than the wider area due to its more diverse economy, with as many as half of the town's mill employees out of work at one time.

Conditions were such that a Local Board of Health was constituted in 1853 and the town itself incorporated in 1878 allowing the enforcement of local laws to improve the town.

Accrington Pals
One well-known association the town has is with the 'Accrington Pals', the nickname given to the smallest home town battalion of volunteers formed to fight in the First World War. The Pals battalions were a peculiarity of the 1914-18 war: Lord Kitchener, the Secretary of State for War, believed that it would help recruitment if friends and work-mates from the same town were able to join up and fight together. Strictly speaking, the 'Accrington Pals' battalion is properly known as the '11th East Lancashire Regiment': the nickname is a little misleading, since of the four 250-strong companies that made up the original battalion only one was composed of men from Accrington. The rest volunteered from other east Lancashire towns such as Burnley, Blackburn and Chorley.

The Pals' first day of action, 1 July 1916, took place in Serre, near Montauban in the north of France. It was part of the 'Big Push' (later known as the Battle of the Somme) that was intended to force the German Army into a retreat from the Western Front, a line they had held since late 1914. The German defences in Serre were supposed to have been obliterated by sustained, heavy, British shelling during the preceding week; however, as the battalion advanced it met with fierce resistance. 235 men were killed and a further 350 wounded — more than half of the battalion — within half an hour. Similarly, desperate losses were suffered elsewhere on the front, in a disastrous day for the British Army (approximately 19,000 British soldiers were killed in a single day).

Later in the year, the East Lancashire Regiment was rebuilt with new volunteers — in all, 865 Accrington men were killed during World War I. All of these names are recorded on a war memorial, an imposing white stone cenotaph, which stands in Oak Hill Park in the south of the town. The cenotaph also lists the names of 173 local fatalities from World War II. The trenches from which the Accrington Pals advanced on 1 July 1916 are still visible in John Copse west of the village of Serre, and there is a memorial there made of Accrington brick.

After the war and until 1986, Accrington Corporation buses were painted in the regimental colours of red and blue with gold lining. The mudguards were painted black as a sign of mourning.

Demography
The 2001 census gave the population of Accrington town as 35,200. The figure for the urban area was 71,220, increased from 70,442 in 1991. This total includes Accrington, Church, Clayton-le-Moors, Great Harwood and Oswaldtwistle.

The 2011 census gave a population of 35,456 for the Accrington built-up area subdivision (which includes Huncoat, Baxenden and Rising Bridge in Rossendale) and a population of 125,000 for the wider Accrington/Rossendale Built-up area. The area in 2001 was listed as 696 ha, whereas in 2011 it was 742.25 ha.

The borough of Hyndburn as a whole has a population of 80,734. This includes Accrington Urban Area and other outlying towns and villages such as; Altham, Rishton, part of Belthorn, and Knuzden and Whitebirk (considered suburbs of Blackburn).

Economy
Historically, cotton and textile machinery were important industries in Accrington, with many mills and factories operating in the town during the 19th and early 20th centuries. The town was renowned for its production of cotton cloth, and several of its mills became famous for their high-quality fabrics, including the Victoria and Jubilee mills. However, like many other towns in Lancashire, the decline of the cotton industry in the mid-20th century led to a significant reduction in manufacturing activity in Accrington.

One notable industrial product associated with Accrington is NORI bricks, a type of iron-hard engineering brick that was produced in nearby Huncoat. The NORI brickworks were established in the 1860s, and their products were widely used in the construction of mills, factories, and other industrial buildings throughout the north of England, as well as Blackpool Tower and the Empire State Building. The brickworks closed in 2013 due to declining demand, but reopened in 2015 after being acquired by a local businessman.

Today, the town's economy is more diverse, with a range of businesses and services operating in the area. Many of the old mill and factory buildings have been repurposed as offices, workshops, and other facilities, providing space for a variety of enterprises. The town also has a number of retail and commercial areas, including the Arndale Centre and the Peel Centre, which are home to a range of shops, restaurants, and other businesses.

Accrington power station was a coal and refuse-fired electricity generating station that operated on Argyle Street adjacent to the gasworks between 1900 and 1958. The power station supplied electricity to Accrington, Haslingden, and the Altham and Clayton-le-Moors areas. The site is now a residential area.

Accrington remains a centre of business and industry in the region, with a rich history of manufacturing and innovation. The area benefits from its location close to major transport links, including the M65 motorway and the East Lancashire railway line, which connect Accrington to other parts of the county and beyond.

In recent years, the town has seen investment in new development projects, including the £60 million "Civic Quarter" regeneration scheme, which aims to revitalize the town center and create new jobs and opportunities for local people. The project includes the construction of a new public square, a state-of-the-art leisure center, and new office and retail spaces, as well as the refurbishment of existing buildings.

In addition to its commercial and industrial activities, Accrington is also home to a number of cultural and recreational amenities. The town has a rich sporting heritage, with Accrington Stanley Football Club, founded in 1968, representing the town in the English Football League. The town also has a strong tradition of brass band music, with several local bands competing at regional and national level. Other cultural attractions in the town include the Haworth Art Gallery, which houses a collection of British art and decorative arts, and the Accrington Market Hall, which runs events and activities.

Poverty, regeneration and investment
Some areas of Accrington have high levels of poverty and deprivation. In one area of the town in 2020, 77% of children were living in poverty. Deprivation increased in Accrington from 2004 to 2010. The Accrington Town Centre Investment Plan 2022-2032 states "Accrington has severe pockets of deprivation – particularly around employment, income and living environment - which has been getting worse during the last 20 years".

The council has a regeneration plan in place, which will, according to the council, boost the local economy. The plan is to upgrade old shops and to build a bus station. A memorial for the Accrington Pals may be built outside the town hall.

The Hyndburn Borough Council plans to spend £10 million to refurbish the town centre, including:

 * Revitalising the town square to attract visitors.
 * Building a new bus station. Plans for the new bus station were put forward in January 2013 and approved in October 2014. The bus station was completed during and officially opened on 11 July 2016. The new station was criticised by traders as the old station was closer and easier to get to.

Half of Blackburn Road is being refurbished and is now being made into a more attractive shopping street, upgrading shops, adding more trees, and repaving the pavements.

As of 2014, two new phases were being built: the first one called the Acorn Park, where new houses were being built with balconies and greener spaces, and Project Phoenix, which will also include new housing.

Geography
Accrington is a hill town located at between the Pennines and the West Pennine Moors, within a bowl and largely encircled by surrounding hills to rising to a height of 409 m in the case of Hameldon Hill to the east. The River Hyndburn or Accrington Brook flows through the centre of the town. Hill settlements origins were as the economic foci of the district engaging in the spinning and weaving of woollen cloth. Wool, lead and coal were other local industries.

Geographical coordinates: 53° 46' 0" North, 2° 21' 0" West. Height above sea level: there is a spot height outside the Market Hall which is 133.5 m the benchmark on the side of the neighbouring Town Hall is 441.10 ft. The highest height in the town is 320 m which is in Baxenden and the lowest at the town hall which is at 132.5 m. Accrington is lowering in elevation travelling northwards towards the Hyndburn. North of the river the elevation rises again, crossing over the watershed between Hyndburn and River Calder, both eventually leading into River Ribble via separate routes. The Hyndburn district further north eventually falls to the modest elevation of the Calder river banks.

Railway
Accrington railway station, located on the East Lancashire Line, provides strong local travel links. The station runs trains locally and from Blackpool to York. However, recent changes to the train timetables have increased the journey time to Preston by up to 1.5 hours, a vital link to London or Scotland. In 2015, a train service to Manchester via the Todmorden Curve opened, providing a new rail link south to Manchester.

Roads
The town is served by junction seven of the M65 motorway and the A680 road, which runs from Rochdale to Whalley. The town is also linked from the A56 dual carriageway which briefly merges with the A680, connecting to the M66 motorway heading towards Manchester. The closest airports are Manchester Airport, Blackpool Airport, and Leeds Bradford Airport, all within 30 miles.

Bus
Several bus companies provide services in the town, including Pilkington Bus, Holmeswood Coaches, Rosso, and Transdev Blazefield subsidiaries Blackburn Bus Company and Burnley Bus Company. Regular bus services connect Accrington to other towns in East Lancashire, including Blackburn, Oswaldtwistle, Rishton, Burnley, and Clitheroe. M&M Coaches provided services in the area until the company ceased business suddenly on 21 September 2016.

Cycleways and Footpaths
The trackbed from Accrington to Baxenden, which was once a rail link south to Manchester, is now a linear treelined cycleway/footpath. The cycleway/footpath is a popular route for cycling and walking, offering views

Public services
Accrington Library, on St James Street was built in 1908 as a Carnegie library. It has a stained glass window by Gustav Hiller and was a place of inspiration for the young Jeanette Winterson.

Near the Tesco supermarket, there is Accrington Skate Park which is popular during the school holidays. On Broadway, Accrington Police Station serves the Borough of Hyndburn. In April 2003, Hyndburn Community Fire Station opened, also serving the Borough of Hyndburn.

Police Services
The town is served by the Lancashire Constabulary Police station on Broadway after moving into town from its previous location on Manchester Road as an effort to save money due to rising expenses and decreasing funding by the government. Crime is very low in Accrington compared to nearby towns.

Policing of the Railway station and railway-owned properties are served by the British Transport Police, nearest post in Preston.

Governance
Accrington is represented in parliament as a part of the constituency of Hyndburn. The constituency boundaries do not align exactly with those of the district of the same name.

Accrington was first represented nationally after the Redistribution of Seats Act 1885 after the 1885 general election by Accrington (UK Parliament constituency). This seat was abolished in the 1983 general election and replaced with the present constituency of Hyndburn (UK Parliament constituency).

Accrington became incorporated as a municipal borough in 1878. Under the Local Government Act 1972, since 1974, the town has formed part of the larger Borough of Hyndburn including the former Urban Districts of Oswaldtwistle, Church, Clayton-le-Moors, Great Harwood and Rishton.

Hyndburn consists of 16 wards, electing a total of 35 councillors. Due to its size Accrington is represented by a number of wards in the Borough of Hyndburn. The town largely consists of the Milnshaw, Peel, Central, Barnfield and Spring Hill wards, although some parts of those wards are in other towns in the borough.

Health
The local hospital is Accrington Victoria Hospital however, as it only deals with minor issues, Accident and Emergency is provided by the Royal Blackburn Hospital. Other services are provided at the Accrington Pals Primary Health Care Centre and the Accrington Acorn Primary Health Care Centre.

Accrington Dialect
The dialect spoken in Accrington is part of the broader Lancashire dialect, which belongs to the larger category of Northern English dialects. This dialect has its roots in the Old English and Middle English languages, with influences from Old Norse due to the Viking invasions in the region. Features of the Accrington dialect include pronunciations, vocabulary, and grammatical structures that distinguish it from other dialects in the Lancashire region.

Vocabulary specific to the Accrington dialect may include words such as "ginnel" (a narrow passage between buildings) or "snap" (referring to a packed lunch or a meal taken to work).

In terms of grammar, the Accrington dialect may exhibit features common to other Northern English dialects, such as the use of "thee" and "thou" for "you" and "were" instead of "was" in certain contexts. Additionally, the Accrington dialect might display non-standard verb conjugations and a preference for certain sentence structures or word order.

The Accrington dialect, like many local dialects, is subject to change and variation over time due to factors such as increased mobility, urbanization, and exposure to other dialects and languages. This may lead to a gradual loss or modification of certain dialect features and an increased convergence with more standardised forms of English.

History of Accrington Dialect
The history of the Accrington dialect is intertwined with the broader history of the Lancashire dialect, as well as the linguistic influences that have shaped the region over time. Although specific information about the Accrington dialect's history is limited, it is reasonable to assume that it has been impacted by similar historical events and linguistic developments as the wider Lancashire area.

Influence of Old English and Middle English
The Accrington dialect has its roots in the Old English and Middle English languages that were spoken in England during the early and late medieval periods, respectively. These languages formed the basis for many dialects in the region, including those spoken in Accrington. As the dialect evolved over time, it retained some elements of these early linguistic influences, which can be observed in the pronunciation, vocabulary, and grammar of the modern Accrington dialect.

Impact of Viking invasions and Old Norse
The Viking invasions during the late 8th to 11th centuries introduced the Old Norse language to the north of England, including the Lancashire region. This contact between Old English and Old Norse speakers likely influenced the Accrington dialect and other Lancashire dialects, with some Old Norse words and grammatical features being incorporated into the local language. As a result, the Accrington dialect shares some common linguistic traits with other Northern English dialects that have been similarly impacted by the Old Norse influence.

Development and changes over time
The Accrington dialect, like other regional dialects, has undergone various changes and developments throughout its history. Factors contributing to these changes may include the expansion and decline of local industries, increased mobility and migration, and exposure to other dialects and languages. Additionally, educational policies and the influence of mass media may have played a role in shaping the modern Accrington dialect, as people in the area increasingly adopt more standardized forms of English in formal settings. Despite these changes, the Accrington dialect continues to exhibit unique features that distinguish it from other dialects in the Lancashire region and reflects the town's rich linguistic heritage.

Pronunciation and Phonetics
The pronunciation and phonetics of the Accrington dialect are characterized by a few distinctive features that set it apart from other dialects in the Lancashire region. However, specific studies and resources focusing solely on the phonetics and pronunciation of the Accrington dialect are currently unavailable. The limited information available is largely based on the broader Lancashire dialect, which may encompass some of the features present in the Accrington dialect. The lack of specific studies or resources highlights a need for more research and documentation on the Accrington dialect to better understand its unique phonetic and pronunciation features.

Vowel shifts and variations
One example of a vowel shift in the Accrington dialect is the pronunciation of the word "acorn" as "akran". This variation demonstrates a tendency in the Accrington dialect to alter vowel sounds compared to Standard English. Other examples of vowel shifts specific to Accrington are not well-documented, but the "akran" example suggests that similar variations may exist in other words and phrases.

Consonant changes
Information on consonant changes specific to the Accrington dialect is scarce. However, based on the broader tendencies of Lancashire dialects and the limited available evidence, it is possible that the Accrington dialect exhibits consonant changes such as the pronunciation of "th" as "d" or "t" (e.g., "them" pronounced as "dem" or "tem") or the elision of certain consonants in some words. Further research is needed to identify and document specific consonant changes unique to the Accrington dialect.

Accent and stress patterns
The accent and stress patterns of the Accrington dialect have not been thoroughly documented in linguistic research. It is difficult to provide specific examples or details about the stress patterns in the Accrington dialect without more comprehensive data. Further study of the Accrington dialect's pronunciation and phonetics is necessary to fully understand its unique accent and stress patterns.

In conclusion, while the Accrington dialect exhibits some unique features, such as the pronunciation of "acorn" as "akran", more research and documentation are needed to provide a comprehensive understanding of the dialect's specific vowel shifts, consonant changes, and accent and stress patterns. The lack of specific studies on the Accrington dialect highlights an opportunity for linguists and researchers to further explore this unique dialect and its pronunciation and phonetics.

Local and Regional Words
Ginnel - A local term for a narrow passage or alleyway between buildings, commonly found in Accrington and other Lancashire towns.

Mither - A verb meaning to bother or annoy someone, or to be fussy or worried about something.

Industry and Occupation-Related Terminology
Tackler - A term referring to a skilled worker responsible for setting up and maintaining looms in the textile industry, which was used in Accrington during the 19th and early 20th centuries.

Landscape and Geography-Related Vocabulary
Clough - A term used in Accrington and other parts of Lancashire to describe a steep-sided, wooded valley or ravine, as in the case of Woodnook Clough. Brook - A small stream or watercourse, such as the Hyndburn Brook, which runs through Accrington.

Ancient Customs and Traditions of Accrington
Accrington, as a historic town, has been home to several ancient customs and traditions that have shaped its local culture and identity. While some of these customs may no longer be practiced, they offer valuable insights into the town's past.

Rush-Bearing Festival
One of the most notable ancient customs in Accrington was the rush-bearing festival. This annual event involved the gathering of rushes from nearby marshlands and meadows to be used as fresh flooring material in local churches. The rushes were then transported to the churches in decorative carts or wagons, accompanied by a festive procession, music, and dancing. This event was once widespread across Lancashire and the North of England, but its prevalence in Accrington is particularly noteworthy.

Wakes Week
Another significant custom in Accrington was Wakes Week, a holiday period that took place in the town and surrounding areas. Typically, it occurred during the summer months and lasted for one week. During this time, local mills and factories closed, allowing workers to enjoy a much-needed break from their labor-intensive occupations. Wakes Week often featured various festivities, such as fairs, carnivals, and other communal events, which brought the community together in celebration.

Local Sports and Games
In the past, Accrington was known for hosting traditional sports and games, which were enjoyed by the local community. Some of these sports included football, cricket, and quoits. These games not only provided entertainment but also fostered a sense of community spirit and camaraderie.

Football team
Accrington Stanley F.C., entered the Football League in 1921 with the formation of the old Third Division (North); after haunting the lower reaches of English football for forty years, they eventually resigned from the League in 1962, due to financial problems, and folded in 1965. The club was reformed three years later and then worked its way through the non-league divisions to reach the Nationwide Conference in 2003. In the 2005–06 season, Stanley, after winning against Woking with three matches to spare, secured a place back in the Football League and the town celebrated with a small parade and honours placed on senior executives of the team. One of the teams relegated— and thus being replaced by Stanley—were Oxford United, who was voted into the Football League to replace the previous Accrington Stanley. The football stadium is called the Crown Ground. Until the 2012–13 season, when Fleetwood Town entered the league, Accrington was the smallest town in England and Wales with a Football League club.

Accrington Stanley Football Club has had its own pub in the town, the Crown, since July 2007.

Team history
An earlier club, Accrington F.C., was one of the twelve founder members of the Football League in 1888. However, their time in league football was even less successful and considerably briefer than that of Accrington Stanley: they dropped out of the league in 1893 and folded shortly afterwards due to financial problems. The town of Accrington thus has the unique "distinction" of having lost two separate clubs from league football. Accrington Stanley F.C. are currently placed in EFL League Two after being relegated from EFL League One in the 2022/23 season, having finished 23rd.

Cricket
Accrington Cricket Club plays at Thorneyholme Road in the Lancashire League. Cricket is also played in parks. Schools nearby have shown major interest in cricket and have held cricket training and tournaments.

Other sports
There are two sports centres, the main one being the Hyndburn Sports Centre, which recently renovated its swimming pool area and is situated near Lidl.

Media
Local news and television programmes are provided by BBC North West and ITV Granada. Television signals are received from the Winter Hill TV transmitter and one of the three local relay transmitters (Woodnook, Pendle Forest and Haslingden ).

Local radio stations are BBC Radio Lancashire on 95.5 FM, Heart North West on 96.9 FM, Smooth North West on 100.4 FM, Greatest Hits Radio Lancashire on 96.5 FM, and Capital Manchester and Lancashire (formerly 2BR) on 99.8 FM.

The town is served by the local newspaper, Accrington Observer which publishes on Fridays.

Education
Accrington has the following primary schools:

 * St Mary's RC Primary School, Clayton le Moors
 * Hyndburn Park Primary School,
 * Peel Park Primary School,
 * Sacred Heart Primary School,
 * Benjamin Hargreaves CE Primary School,
 * Springhill County Primary School,
 * Accrington Huncoat Primary School,
 * St Johns and St Augustines CE Primary School,
 * St Mary Magdalen's CE Primary School,
 * St Nicholas' CE Primary School,
 * Woodnook Primary School,
 * St James CE Primary School, Altham,
 * St Johns CE Primary School, Baxenden,
 * All Saints CE Primary School,
 * Mount Pleasant Primary School,
 * Green Haworth CE Primary School,
 * Stonefold CE Primary School,
 * St Peters CE Primary School.
 * St Mary's RC Primary School, Oswaldtwistle.
 * St Anne's and St Joseph's RC Primary School
 * St Oswald's RC Primary School
 * Hippings Methodist Primary School Oswaldtwistle
 * St Andrews CoE Primary School Oswaldtwistle
 * St Oswalds CoE Primary School Knuzden
 * West End Primary School Oswaldtwistle
 * Moor End Community Primary School Oswaldtwistle
 * St Paul's CoE Primary School Oswaldtwistle

The secondary schools serving Accrington are:
 * Accrington Academy
 * Heathland School
 * The Hollins
 * The Hyndburn Academy
 * Mount Carmel Roman Catholic High School
 * Rhyddings
 * St Christopher's Church of England High School

The college in the town centre is Accrington and Rossendale College; nearby universities include University Centre at Blackburn College, and the University of Central Lancashire in Preston.

Haworth Art Gallery
The Haworth Art Gallery is an art museum located in Accrington, Lancashire, England. The gallery is housed in a Tudor-style mansion, originally known as Hollins Hill, which was built in 1909 by William Haworth, a local cotton manufacturer. Upon his death in 1913, William Haworth bequeathed the mansion and its surrounding parkland to the people of Accrington. The gallery opened in 1921.

The Haworth Art Gallery holds the largest public collection of Tiffany glass in Europe, known as the Tiffany Glass Collection. The collection was donated by Joseph Briggs, an Accrington native who worked for the famous American artist and designer Louis Comfort Tiffany. In addition to the Tiffany Glass Collection, the gallery holds a range of artwork, including 19th and 20th-century oil paintings, watercolours, prints, and sculptures.

The Haworth Art Gallery also holds temporary exhibitions showing contemporary art by local and national artists.

The Viaduct
The Viaduct is a bridge which has a railway line on it, it goes through the town and has many storage units and shop on sale by National Rail. The Viaduct ends at the Accrington Eco Station.

Town Hall
Accrington Town Hall was built in memory of Sir Robert Peel and opened as the Peel Institute in 1858; it is also listed.

The Arcade
The Arcade is a Victorian shopping centre with about 10-15 shops and restaurants.

Oakhill Park
Oakhill Park is a large and old park with a view of Accrington. It has won awards such as the best park in Lancashire. It has also been awarded an Eco Award. It is on Manchester Road.

Haworth Park
Haworth Park can be accessed from Manchester Road and is off Hollins Lane at the top of Harcourt Road. The Park was originally William Haworth's private residence. The Haworth Art Gallery holds the Tiffany Glass collection.

The Coppice and Peel Park
Peel Park is a green space in the centre of Accrington. The park was opened by William Peel on 29 September 1909 and was originally called the Corporation Park. The park was renamed in honour of William Peel, the grandson of Sir Robert Peel, in recognition of his service as a Liberal MP for the town. The park covers an area of approximately 18 acres and includes a wide range of features, including a lake, flower gardens, a bandstand, and a bowling green.

The Coppice is a hill in the park, and provides a 2.2-mile scenic walk around the park, offering visitors views of the surrounding area. The Coppice has been part of the park since it was first opened, and there have been refurbishments to the paths and monuments at the top of the hill over the years.

In 2009, the people of Accrington celebrated the centenary of the Coppice being handed over to the town. The occasion was marked with a series of events and activities, including a refurbishment of the paths and monument at the top of the hill. Since then, there have been several revamps to the playground area of the park.

Events and festivals are held in the park throughout the year, including the annual Accrington Food and Drink Festival, which takes place in the summer.

Early landowners
This section outlines the contributions of landowning families, including the de Lacy, Walmsley, Peel, Hargreaves and Haworth families, to the development of Accrington.

De Lacy family
The de Lacy family were the first recorded landowners in Accrington, instrumental in the town's establishment as a regional center for agriculture and trade.

Walmsley family
The Walmsley family acquired the manor of Accrington in the 16th century and owned several mills, contributing to the expansion of Accrington's textile industry.

Peel family
The Peel family were key figures in the 18th and 19th centuries, with Sir Robert Peel, 1st Baronet, establishing textile mills in the area, significantly boosting Accrington's economy.

Hargreaves family
The Hargreaves family built the Broad Oak Print Works in 1778, which became one of the largest textile printing establishments in the region.

Haworth family
The Haworth family were prominent landowners in Accrington, with James Haworth establishing Haworth Mill in the early 1800s. The family's investments in local industry contributed to the town's economic development.

Peel, Yates and Co.
Peel, Yates and Co. was a partnership between the Peel family and the Yates family. The Peel family, led by Robert Peel (1750-1830), and the Yates family, led by William Yates (1769-1849), established Peel, Yates and Co. in 1795. The company owned and operated several cotton mills in Accrington, including the Woodnook Mill, which employed around 800 people during its peak operation.

Duckworth Family
The Duckworth family were landowners and industrialists in Accrington during the 19th century. They invested in the local textile industry, owning several mills, such as the Broad Oak Mill and the Spring Hill Mill. The Duckworth family's mills employed hundreds of workers.

Birtwistle family
The Birtwistle family were involved in the cotton industry in Accrington, owning and operating cotton mills during the 19th century. Members of the family, including John Birtwistle (1807-1884), owned mills like the Church Bank Mill and the Wellington Mill, employing over 1,000 workers between the two establishments.

Holden family
The Holden family contributed to Accrington's development through their involvement in various industries, such as coal mining and brick manufacturing. The family-owned Accrington Brick and Tile Company, established by Joseph Holden

Notable residents

 * Alan Ramsbottom, professional cyclist
 * Andy Hargreaves, academic
 * Andy Kanavan, rock drummer with Dire Straits and Level 9 was born in the town
 * Jenny (Jane) Kenney, sister of suffragette Annie Kenney who taught at Montessori school in the 1900s
 * Anthony Rushton, tech entrepreneur
 * Barry Stanton (actor), actor for RSC and films such as The Madness of King George
 * David Lloyd, cricketer, now a pundit for Sky Sports
 * Diana Vickers, singer-songwriter, stage actress and fashion designer
 * Edward Ormerod, mining engineer and inventor of the Ormerod safety link for use in coal mines
 * Frederick Higginbottom, journalist and newspaper editor
 * Graeme Fowler, cricketer, former England batsman, cricket coach and occasional pundit on BBC Radio's Test Match Special
 * Harrison Birtwistle, composer
 * Hollie Steel, Britain's Got Talent finalist of 2009
 * Jeanette Winterson, author; Oranges Are Not the Only Fruit is an account of her childhood in the town
 * John Rex Whinfield, chemist, inventor of Terylene (polyester), the first completely synthetic fibre invented in UK
 * John Virtue, artist
 * Jon Anderson, singer with rock band Yes, was born in the town
 * Jonathan Slinger, RADA trained actor
 * Julie Hesmondhalgh, actor, Hayley Cropper in the TV Soap Coronation Street
 * Mick O'Shea, author and scriptwriter
 * Mike Duxbury, footballer, was born in the town
 * Mystic Meg, astrologer, was born in the town as Margaret Anne Lake in 1942
 * Netherwood Hughes, World War I veteran, died in 2009, aged 108
 * Nicholas Freeston (1907-1978), Award-winning Lancashire poet
 * Pauline Aitken, artist
 * Paul Manning, undercover police officer and whistleblower
 * Reece Bibby, member of Stereo Kicks and 2014 finalist of The X Factor. Now a member of the band New Hope Club
 * Ron Hill, long-distance and marathon runner
 * Thomas Birtwistle, trade unionist
 * Vicky Entwistle, actor, Janice Battersby in the TV Soap Coronation Street
 * William Macrorie bishop of Maritzburg
 * Stephen Heys, footballer
 * Val Robinson, footballer and field hockey player

title: Accrington