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Dr. Strangelove

Dr. Strangelove or: How I Learned to Stop Worrying and Love the Bomb (known simply and more commonly as Dr. Strangelove) is a 1964 political satire black comedy film cowritten, produced, and directed by Stanley Kubrick and starring Peter Sellers in three roles, including the title character. The film, financed and released by Columbia Pictures, was a co-production between the United States and the United Kingdom.

The film, which satirizes the Cold War fears of a nuclear conflict between the Soviet Union and the United States, also stars George C. Scott, Sterling Hayden, Keenan Wynn, Slim Pickens, and Tracy Reed and is loosely based on the thriller novel Red Alert (1958) by Peter George, who also co-wrote the screenplay with Kubrick and Terry Southern.

The story concerns an unhinged United States Air Force general who orders a pre-emptive nuclear attack on the Soviet Union. It separately follows the President of the United States (Sellers), his advisors, the Joint Chiefs of Staff, and a Royal Air Force exchange officer (Sellers) as they attempt to prevent the crew of a B-52 (following orders from the general) from bombing the Soviet Union and starting a nuclear war.

The film is often considered one of the best comedies ever made and one of the greatest films of all time. In 1998, the American Film Institute ranked it twenty-sixth in its list of the best American movies (in the 2007 edition, the film ranked thirty-ninth), and in 2000, it was listed as number three on its list of the funniest American films. In 1989, the United States Library of Congress included Dr. Strangelove as one of the first 25 films selected for preservation in the National Film Registry for being "culturally, historically, or aesthetically significant". The film received four Academy Award nominations, including Best Picture, Best Director, Best Adapted Screenplay, and Best Actor for Sellers. The film was also nominated for seven BAFTA Film Awards, winning Best Film From Any Source, Best British Film, and Best Art Direction (Black and White), and it also won the Hugo Award for Best Dramatic Presentation.

Plot
United States Air Force Brigadier General Jack D. Ripper, the commander of Burpelson Air Force Base, orders his executive officer, Group Captain Lionel Mandrake (an exchange officer from the Royal Air Force), to put the base on alert (condition red, the most intense lockdown status), confiscate all privately owned radios from base personnel and issue "Wing Attack Plan R" to the planes of the 843rd Bomb Wing. At the time of issuance of that order, the planes, flying B-52 bombers armed with hydrogen bombs, are on airborne alert two hours from their targets inside the USSR. All the aircraft commence attack flights on the USSR and set their radios to allow communications only through their CRM 114 discriminators, which are designed to accept only communications preceded by a secret three-letter code known only to General Ripper. Happening upon a radio that had been missed earlier and hearing regular civilian broadcasting, Mandrake realizes that no attack order has been issued by the Pentagon and tries to stop Ripper, who locks them both in his office. Ripper tells Mandrake that he believes the Soviets have been fluoridating American water supplies to pollute the "precious bodily fluids" of Americans. Mandrake realizes Ripper has gone completely mad. In the War Room at the Pentagon, General Buck Turgidson briefs President Merkin Muffley and other officers about how "Plan R" enables a senior officer to launch a retaliatory nuclear attack on the Soviets if all of his superior officers have been killed in a first strike on the United States. Trying every CRM code combination to issue a recall order would require two days, so Muffley orders the U.S. Army to storm the base and arrest General Ripper. Turgidson, noting the slim odds of recalling the planes in time, then proposes that Muffley not only let the attack proceed but send reinforcements. Muffley rejects Turgidson's recommendation and instead brings Soviet ambassador Alexei de Sadeski into the War Room to telephone Soviet Premier Dimitri Kissov. Muffley warns the Premier of the impending attack and offers to reveal the targets, flight plans, and defensive systems of the bombers so that the Soviets can protect themselves.

After a heated discussion with the Premier, the ambassador informs President Muffley that the Soviet Union created a doomsday machine as a nuclear deterrent; it consists of many buried cobalt bombs, which are set to detonate automatically should any nuclear attack strike the country. The resulting nuclear fallout would render the Earth's surface uninhabitable for 93 years. The device cannot be deactivated, as it is programmed to explode if any such attempt is made. The President's German scientific advisor, the paraplegic former Nazi Dr. Strangelove, points out that such a doomsday machine would only have been an effective deterrent if everyone knew about it; de Sadeski replies that the Soviet Premier had planned to reveal its existence to the world the following week at the Party Congress.

When the U.S. Army troops gain control of Burpelson, General Ripper commits suicide. Mandrake deduces Ripper's CRM code from doodles on his desk blotter and relays it to the Pentagon. Using the code, Strategic Air Command successfully recalls all of the bombers except for one, commanded by Major T. J. "King" Kong. Because its radio equipment was damaged by a Soviet SAM, it is unable to receive or send communications. To conserve fuel, Kong flies below radar and switches targets. Because the Soviet attack also damaged the bomb bay doors, Kong enters the bay and repairs the electrical wiring. When he is successful, the bomb drops with him straddling it. Kong joyously hoots and waves his cowboy hat as he rides the falling bomb to his death.

In the War Room, Dr. Strangelove recommends that the President gather several hundred thousand people to live in deep underground mines where the radiation will not penetrate. Worried that the Soviets will do the same, Turgidson warns about a "mineshaft gap" while de Sadeski secretly photographs the War Room. Dr. Strangelove suddenly stands up out of his wheelchair. As Strangelove exclaims, "Mein Führer, I can walk!" the doomsday device explodes.

Cast

 * Peter Sellers as:
 * Group Captain Lionel Mandrake, a British RAF exchange officer
 * Merkin Muffley, the President of the United States
 * Dr. Strangelove (né Merkwürdigliebe), the wheelchair-using nuclear war expert and former Nazi, who has alien hand syndrome
 * George C. Scott as General Buck Turgidson, Chairman of the Joint Chiefs of Staff
 * Sterling Hayden as Brigadier General Jack D. Ripper, paranoid commander of Burpelson Air Force Base, which is part of the Strategic Air Command.
 * Keenan Wynn as Colonel "Bat" Guano, the Army officer who finds Mandrake and Ripper
 * Jack Creley as Mr. Staines, National Security Advisor
 * Slim Pickens as Major T. J. "King" Kong, the B-52 bomber's commander and pilot
 * Peter Bull as Soviet Ambassador Alexei de Sadeski
 * James Earl Jones as Lieutenant Lothar Zogg, the B-52's bombardier (film debut)
 * Tracy Reed as Miss Scott, General Turgidson's secretary and mistress, the film's only female character. She also appears as "Miss Foreign Affairs", the Playboy Playmate in Playboy June 1962 issue, which Major Kong is shown perusing at one point.
 * Shane Rimmer as Capt. Ace Owens, the co-pilot of the B-52

Peter Sellers's multiple roles
Columbia Pictures agreed to finance the film if Peter Sellers played at least four major roles. The condition stemmed from the studio's opinion that much of the success of Kubrick's previous film Lolita (1962) was based on Sellers's performance, in which his single character assumes several identities. Sellers also played three roles in The Mouse That Roared (1959). Kubrick accepted the demand, later saying that "such crass and grotesque stipulations are the sine qua non of the motion-picture business."

Sellers ended up playing three of the four roles written for him. He had been expected to play Air Force Major T. J. "King" Kong, the B-52 aircraft commander, but from the beginning, Sellers was reluctant. He felt his workload was too heavy and worried he would not properly portray the character's Texan accent. Kubrick pleaded with him, and he asked the screenwriter Terry Southern (who had been raised in Texas) to record a tape with Kong's lines spoken in the correct accent, which he practiced using Southern's tapes. But after the start of shooting in the aircraft, Sellers sprained his ankle and could no longer work in the cramped aircraft mockup.

Sellers improvised much of his dialogue, with Kubrick incorporating the ad-libs into the written screenplay so that the improvised lines became part of the canonical screenplay, a practice known as retroscripting.

Group Captain Lionel Mandrake
According to film critic Alexander Walker, the author of biographies of both Sellers and Kubrick, the role of Group Captain Lionel Mandrake was the easiest of the three for Sellers to play, since he was aided by his experience of mimicking his superiors while serving in the RAF during World War II. There is also a heavy resemblance to Sellers's friend and occasional co-star Terry-Thomas and the prosthetic-limbed RAF flying ace Sir Douglas Bader.

President Merkin Muffley
For his performance as President Merkin Muffley, Sellers assumed a Midwestern American English accent. Sellers drew inspiration for the role from Adlai Stevenson, a former Illinois governor who was the Democratic candidate for the 1952 and 1956 presidential elections and the U.N. ambassador during the Cuban Missile Crisis.

In early takes, Sellers simulated cold symptoms to emphasize the character's apparent weakness. That caused frequent laughter among the film crew, ruining several takes. Kubrick ultimately found this comic portrayal inappropriate, feeling Muffley should be a serious character. In later takes, Sellers played the role straight, though the President's cold is still evident in several scenes.

Dr. Strangelove

Dr. Strangelove is a scientist and former Nazi, suggesting Operation Paperclip, the US effort to recruit top German technical talent at the end of World War II. He serves as President Muffley's scientific adviser in the War Room. When General Turgidson wonders aloud to Mr. Staines (Jack Creley), what kind of name "Strangelove" is, possibly a "Kraut name", Staines responds that Strangelove's original German surname was Merkwürdigliebe ("Strange love" in German) and that "he changed it when he became a citizen". Strangelove accidentally addresses the president as Mein Führer twice in the film. Dr. Strangelove did not appear in the book Red Alert.

The character is an amalgamation of RAND Corporation strategist Herman Kahn, rocket scientist Wernher von Braun (a central figure in Nazi Germany's rocket development program recruited to the US after the war), and Edward Teller, the "father of the hydrogen bomb". Rumors claimed the character was based on Henry Kissinger, but Kubrick and Sellers denied this; Sellers said: "Strangelove was never modeled after Kissinger—that's a popular misconception. It was always Wernher von Braun." Furthermore, Henry Kissinger points out in his memoirs that at the time of the writing of Dr. Strangelove, he was a little-known academic.

The wheelchair-using Strangelove furthers a Kubrick trope of the menacing, seated antagonist, first depicted in Lolita through the character "Dr. Zaempf". Strangelove's accent was influenced by that of Austrian-American photographer Weegee, who worked for Kubrick as a special photographic effects consultant. Strangelove's appearance echoes the mad scientist archetype as seen in the character Rotwang in Fritz Lang's film Metropolis (1927). Sellers's Strangelove takes from Rotwang the single black gloved hand (which, in Rotwang's case, is mechanical because of a lab accident), the wild hair, and, most importantly, his ability to avoid being controlled by political power. According to Alexander Walker, Sellers improvised Dr. Strangelove's lapse into the Nazi salute, borrowing one of Kubrick's black leather gloves for the uncontrollable hand that makes the gesture. Dr. Strangelove apparently has alien hand syndrome. Kubrick wore the gloves on the set to avoid being burned when handling hot lights, and Sellers, recognizing the potential connection to Lang's work, found them to be menacing.

Slim Pickens as Major T. J. "King" Kong
Slim Pickens, an established character actor and veteran of many Western films, was eventually chosen to replace Sellers as Major Kong after Sellers' injury. John Wayne was offered the role after Sellers was injured, but he never responded to Kubrick's offer. Dan Blocker of the Bonanza western television series was also approached to play the part, but according to Southern, Blocker's agent rejected the script as being "too pinko". Kubrick then recruited Pickens, whom he knew from his brief involvement in a Marlon Brando western film project that was eventually filmed as One-Eyed Jacks.

His fellow actor James Earl Jones recalls, "He was Major Kong on and off the set—he didn't change a thing—his temperament, his language, his behavior." Pickens was not told that the movie was a black comedy, and he was only given the script for scenes he was in to get him to play it "straight".

Kubrick's biographer John Baxter explained, in the documentary Inside the Making of Dr. Strangelove: "As it turns out, Slim Pickens had never left the United States. He had to hurry and get his first passport. He arrived on the set, and somebody said, 'Gosh, he's arrived in costume!', not realizing that that's how he always dressed ... with the cowboy hat and the fringed jacket and the cowboy boots—and that he wasn't putting on the character—that's the way he talked."

Pickens, who had previously played only supporting and character roles, said that his appearance as Maj. Kong greatly improved his career. He later commented, "After Dr. Strangelove, my salary jumped five times, and assistant directors started saying 'Hey, Slim' instead of 'Hey, you'."

George C. Scott as General Buck Turgidson
George C. Scott played the role of General Buck Turgidson, the Chairman of the Joint Chiefs of Staff. In this capacity General Turgidson was the nation's highest-ranking military officer and the principal military advisor to the President and the National Security Council. He is seen during most of the movie advising President Muffley on the best steps to take in order to stop the fleet of B-52 Stratofortresses that was deployed by Brigadier General Jack D. Ripper to drop nuclear bombs on Soviet soil.

According to James Earl Jones, Kubrick tricked Scott into playing the role of Gen. Turgidson in a much more outlandish manner than Scott was comfortable doing. According to Jones, Kubrick talked Scott into doing absurd "practice" takes, which Kubrick told Scott would never be used, as a way to warm up for the "real" takes. According to Jones, Kubrick used these takes rather than the more restrained ones in the final film, allegedly causing Scott to swear never to work with Kubrick again.

During the filming, Kubrick and Scott had different opinions regarding certain scenes, but Kubrick obtained Scott's compliance largely by beating him at chess, which they played frequently on the set.

Novel and screenplay
Stanley Kubrick started with nothing but a vague idea to make a thriller about a nuclear accident that built on the widespread Cold War fear for survival. While doing research, Kubrick gradually became aware of the subtle and paradoxical "balance of terror" between nuclear powers. At Kubrick's request, Alastair Buchan (the head of the Institute for Strategic Studies) recommended the thriller novel Red Alert by Peter George. Kubrick was impressed with the book, which had also been praised by game theorist and future Nobel Prize in Economics winner Thomas Schelling in an article written for the Bulletin of the Atomic Scientists and reprinted in The Observer, and immediately bought the film rights. In 2006, Schelling wrote that conversations between Kubrick, Schelling, and George in late 1960 about a treatment of Red Alert updated with intercontinental missiles eventually led to the making of the film.

In collaboration with George, Kubrick started writing a screenplay based on the book. While writing the screenplay, they benefited from some brief consultations with Schelling and later, Herman Kahn. In following the tone of the book, Kubrick originally intended to film the story as a serious drama. However, he began to see comedy inherent in the idea of mutual assured destruction as he wrote the first draft. He later said:"My idea of doing it as a nightmare comedy came in the early weeks of working on the screenplay. I found that in trying to put meat on the bones and to imagine the scenes fully, one had to keep leaving out of it things which were either absurd or paradoxical, in order to keep it from being funny; and these things seemed to be close to the heart of the scenes in question."

Among the titles that Kubrick considered for the film were Dr. Doomsday or: How to Start World War III Without Even Trying, Dr. Strangelove's Secret Uses of Uranus, and Wonderful Bomb. After deciding to make the film a black comedy, Kubrick brought in Terry Southern as a co-writer in late 1962. The choice was influenced by reading Southern's comic novel The Magic Christian, which Kubrick had received as a gift from Peter Sellers, and which itself became a Sellers film in 1969. Southern made important contributions to the film, but his role led to a rift between Kubrick and Peter George; after Life magazine published a photo-essay on Southern in August 1964 which implied that Southern had been the script's principal author—a misperception neither Kubrick nor Southern did much to dispel— George wrote a letter to the magazine, published in its September 1964 issue, in which he pointed out that he had both written the film's source novel and collaborated on various incarnations of the script over a period of ten months, whereas "Southern was briefly employed ... to do some additional rewriting for Kubrick and myself and fittingly received a screenplay credit in behind Mr. Kubrick and myself."

Sets and filming
Dr. Strangelove was filmed at Shepperton Studios, near London, as Sellers was in the middle of a divorce at the time and unable to leave England. The sets occupied three main sound stages: the Pentagon War Room, the B-52 Stratofortress bomber and the last one containing both the motel room and General Ripper's office and outside corridor. The studio's buildings were also used as the Air Force base exterior. The film's set design was done by Ken Adam, the production designer of several James Bond films (at the time he had already worked on Dr. No). The black-and-white cinematography was by Gilbert Taylor, and the film was edited by Anthony Harvey and an uncredited Kubrick. The original musical score for the film was composed by Laurie Johnson, and the special effects were done by Wally Veevers. The opening theme is an instrumental version of "Try a Little Tenderness." The theme of the chorus from the bomb run scene is a modification of "When Johnny Comes Marching Home." Sellers and Kubrick got along well during the film's production and shared a love of photography.

For the War Room, Ken Adam first designed a two-level set which Kubrick initially liked, only to decide later that it was not what he wanted. Adam next began work on the design that was used in the film, an expressionist set that was compared with The Cabinet of Dr. Caligari and Fritz Lang's Metropolis. It was an enormous concrete room (130 ft long and 100 ft wide, with a 35 ft-high ceiling) suggesting a bomb shelter, with a triangular shape (based on Kubrick's idea that this particular shape would prove the most resistant against an explosion). One side of the room was covered with gigantic strategic maps reflecting in a shiny black floor inspired by dance scenes in Fred Astaire films. In the middle of the room there was a large circular table lit from above by a circle of lamps, suggesting a poker table. Kubrick insisted that the table would be covered with green baize (although this could not be seen in the black-and-white film) to reinforce the actors' impression that they are playing 'a game of poker for the fate of the world.' Kubrick asked Adam to build the set ceiling in concrete to force the director of photography to use only the on-set lights from the circle of lamps. Moreover, each lamp in the circle of lights was carefully placed and tested until Kubrick was happy with the result.

Lacking cooperation from the Pentagon in the making of the film, the set designers reconstructed the aircraft cockpit to the best of their ability by comparing the cockpit of a B-29 Superfortress and a single photograph of the cockpit of a B-52 and relating this to the geometry of the B-52's fuselage. The B-52 was state-of-the-art in the 1960s, and its cockpit was off-limits to the film crew. When some United States Air Force personnel were invited to view the reconstructed B-52 cockpit, they said that "it was absolutely correct, even to the little black box which was the CRM." It was so accurate that Kubrick was concerned about whether Adam's team had carried out all its research legally.

In several shots of the B-52 flying over the polar ice en route to Russia, the shadow of the actual camera plane, a Boeing B-17 Flying Fortress, is visible on the icecap below. The B-52 was a scale model composited into the Arctic footage, which was sped up to create a sense of jet speed. Home movie footage included in Inside the Making of Dr. Strangelove on the 2001 Special Edition DVD release of the film shows clips of the B-17 with a cursive "Dr. Strangelove" painted over the rear entry hatch on the right side of the fuselage.

In 1967, some of the flying footage from Dr. Strangelove was re-used in The Beatles' television film Magical Mystery Tour. As told by editor Roy Benson in the BBC Radio Documentary Celluloid Beatles, the production team of Magical Mystery Tour lacked footage to cover the sequence for the song "Flying." Benson had access to the aerial footage filmed for the B-52 sequences of Dr. Strangelove, which was stored at Shepperton Studios. The use of the footage prompted Kubrick to call Benson to complain.

Fail Safe
Red Alert author Peter George collaborated on the screenplay with Kubrick and satirist Terry Southern. Red Alert was more solemn than its film version, and it did not include the character Dr. Strangelove, though the main plot and technical elements were quite similar. A novelization of the actual film, rather than a reprint of the original novel, was published by Peter George, based on an early draft in which the narrative is bookended by the account of aliens, who, having arrived at a desolated Earth, try to piece together what has happened. It was reissued in October 2015 by Candy Jar Books, featuring never-before-published material on Strangelove's early career.

During the filming of Dr. Strangelove, Stanley Kubrick learned that Fail Safe, a film with a similar theme, was being produced. Although Fail Safe was to be an ultrarealistic thriller, Kubrick feared that its plot resemblance would damage his film's box office potential, especially if it were released first. Indeed, the novel Fail-Safe (on which the film is based) is so similar to Red Alert that Peter George sued on charges of plagiarism and settled out of court. What worried Kubrick the most was that Fail Safe boasted the acclaimed director Sidney Lumet and the first-rate dramatic actors Henry Fonda as the American president and Walter Matthau as the advisor to the Pentagon, Professor Groeteschele. Kubrick decided to throw a legal wrench into Fail Safe's production gears. Lumet recalled in the documentary Inside the Making of Dr. Strangelove: "We started casting. Fonda was already set ... which of course meant a big commitment in terms of money. I was set, Walter [Bernstein, the screenwriter] was set ... And suddenly, this lawsuit arrived, filed by Stanley Kubrick and Columbia Pictures."

Kubrick argued that Fail Safe's own source novel Fail-Safe (1962) had been plagiarized from Peter George's Red Alert, to which Kubrick owned creative rights. He pointed out unmistakable similarities in intentions between the characters Groeteschele and Strangelove. The plan worked, and the suit was settled out of court, with the agreement that Columbia Pictures, which had financed and was distributing Strangelove, also buy Fail Safe, which had been an independently financed production. Kubrick insisted that the studio release his movie first, and Fail Safe opened eight months after Dr. Strangelove, to critical acclaim but mediocre ticket sales.

Ending
The end of the film shows Dr. Strangelove exclaiming, "Mein Führer, I can walk!" before cutting to footage of nuclear explosions, with Vera Lynn and her audience singing "We'll Meet Again". This footage comes from nuclear tests such as shot "Baker" of Operation Crossroads at Bikini Atoll, the Trinity test, a test from Operation Sandstone and the hydrogen bomb tests from Operation Redwing and Operation Ivy. In some shots, old warships (such as the German heavy cruiser Prinz Eugen), which were used as targets, are plainly visible. In others, the smoke trails of rockets used to create a calibration backdrop can be seen. Former Goon Show writer and friend of Sellers Spike Milligan was credited with suggesting Vera Lynn's song for the ending.

Original ending
It was originally planned for the film to end with a scene that depicted everyone in the War Room involved in a pie fight. Accounts vary as to why the pie fight was cut. In a 1969 interview, Kubrick said, "I decided it was farce and not consistent with the satiric tone of the rest of the film." Critic Alexander Walker observed that "the cream pies were flying around so thickly that people lost definition, and you couldn't really say whom you were looking at." Nile Southern, son of screenwriter Terry Southern, suggested the fight was intended to be less jovial: "Since they were laughing, it was unusable, because instead of having that totally black, which would have been amazing, like, this blizzard, which in a sense is metaphorical for all of the missiles that are coming, as well, you just have these guys having a good old time. So, as Kubrick later said, 'it was a disaster of Homeric proportions.

Effects of the Kennedy assassination on the film
A first test screening of the film was scheduled for November 22, 1963, the day of the assassination of John F. Kennedy. The film was just weeks from its scheduled premiere, but because of the assassination, the release was delayed until late January 1964, as it was felt that the public was in no mood for such a film any sooner.

During post-production, one line by Slim Pickens, "a fella could have a pretty good weekend in Dallas with all that stuff", was dubbed to change "Dallas" to "Vegas", since Dallas was where Kennedy was killed. The original reference to Dallas survives in the English audio of the French-subtitled version of the film.

The assassination also serves as another possible reason that the pie-fight scene was cut. In the scene, after Muffley takes a pie in the face, General Turgidson exclaims: "Gentlemen! Our gallant young president has been struck down in his prime!" Editor Anthony Harvey stated that the scene "would have stayed, except that Columbia Pictures were horrified, and thought it would offend the president's family." Kubrick and others have said that the scene had already been cut before preview night because it was inconsistent with the rest of the film.

Re-release in 1994
In 1994, the film was re-released. While the 1964 release used a 1.85:1 aspect ratio, the new print was in the slightly squarer 1.66:1 (5:3) ratio that Kubrick had originally intended.

Satirizing the Cold War
Dr. Strangelove ridicules nuclear war planning. It mocks numerous contemporary Cold War attitudes such as the "missile gap" but it primarily directs its satire on the theory of mutually assured destruction (MAD), in which each side is supposed to be deterred from a nuclear war by the prospect of a universal cataclysm regardless of who "won". Military strategist and former physicist Herman Kahn, in the book On Thermonuclear War (1960), used the theoretical example of a "doomsday machine" to illustrate the limitations of MAD, which was developed by John von Neumann.

The concept of such a machine is consistent with MAD doctrine when it is logically pursued to its conclusion. It thus worried Kahn that the military might like the idea of a doomsday machine and build one. Kahn, a leading critic of MAD and the Eisenhower administration's doctrine of massive retaliation upon the slightest provocation by the USSR, considered MAD to be foolish bravado, and urged the United States to instead plan for proportionality, and thus even a limited nuclear war. With this reasoning, Kahn became one of the architects of the flexible response doctrine which, while superficially resembling MAD, allowed for the possibility of responding to a limited nuclear strike with a proportional, or calibrated, return of fire (see Conflict escalation).

Kahn educated Kubrick on the concept of the semi-realistic "cobalt-thorium G" doomsday machine, and then Kubrick used the concept for the film. Kahn in his writings and talks would often come across as cold and calculating, for example, with his use of the term "megadeaths" and in his willingness to estimate how many human lives the United States could lose and still rebuild economically. Kahn's dispassionate attitude towards millions of deaths is reflected in Turgidson's remark to the president about the outcome of a preemptive nuclear war: "Mr. President, I'm not saying we wouldn't get our hair mussed. But I do say no more than ten to twenty million killed, tops, uh, depending on the breaks." Turgidson has a binder that is labelled "World Targets in Megadeaths," a term coined in 1953 by Kahn and popularized in his 1960 book On Thermonuclear War.

The fallout-shelter-network proposal mentioned in the film, with its inherently high radiation protection characteristics, has similarities and contrasts to that of the real Swiss civil defense network. Switzerland has an overcapacity of nuclear fallout shelters for the country's population size, and by law, new homes must still be built with a fallout shelter. If the US did that, it would violate the spirit of MAD and, according to MAD adherents, allegedly destabilize the situation because the US could launch a first strike and its population would largely survive a retaliatory second strike (see MAD § Theory).

To rebut early 1960s novels and Hollywood films like Fail-Safe and Dr. Strangelove, which raised questions about US control over nuclear weapons, the Air Force produced a documentary film, SAC Command Post, to demonstrate its responsiveness to presidential command and its tight control over nuclear weapons. However, later academic research into declassified documents showed that U.S. military commanders had been given presidentially authorized pre-delegation for the use of nuclear weapons during the early Cold War, showing that this aspect of the film's plot was plausible.

The characters of Buck Turgidson and Jack Ripper both satirize the real-life Gen. Curtis LeMay of the Strategic Air Command.

Sexual themes
In the months following the film's release, director Stanley Kubrick received a fan letter from Legrace G. Benson of the Department of History of Art at Cornell University interpreting the film as being sexually-layered. The director wrote back to Benson and confirmed the interpretation, "Seriously, you are the first one who seems to have noticed the sexual framework from intromission (the planes going in) to the last spasm (Kong's ride down and detonation at target)."

Release
The film was a popular success, earning US$4,420,000 in rentals in North America during its initial theatrical release.

Critical response
Dr. Strangelove is Kubrick's highest-rated film on Rotten Tomatoes, holding a 98% approval rating based on 96 reviews, with an average rating of 9.1/10. The site's summary states that "Stanley Kubrick's brilliant Cold War satire remains as funny and razor-sharp today as it was in 1964." The film also holds a score of 97 out of 100 on Metacritic, based on 32 reviews, indicating "universal acclaim". The film is ranked number 7 in the All-Time High Scores chart of Metacritic's Video/DVD section. It was selected for preservation in the United States National Film Registry.

Dr. Strangelove is on Roger Ebert's list of The Great Movies, and he described it as "arguably the best political satire of the century". One of the most celebrated of all film comedies, in 1998, Time Out conducted a reader's poll and Dr. Strangelove was voted the 47th greatest film of all time. Entertainment Weekly voted it at No. 14 on their list of 100 Greatest Movies of All Time. in 2002, it was ranked as the 5th best film in Sight & Sound poll of best films. John Patterson of The Guardian wrote, "There had been nothing in comedy like Dr Strangelove ever before. All the gods before whom the America of the stolid, paranoid 50s had genuflected—the Bomb, the Pentagon, the National Security State, the President himself, Texan masculinity and the alleged Commie menace of water-fluoridation—went into the wood-chipper and never got the same respect ever again." It is also listed as number 26 on Empire's 500 Greatest Movies of All Time, and in 2010 it was listed by Time magazine as one of the 100 best films since the publication's inception in 1923. The Writers Guild of America ranked its screenplay the 12th best ever written.

In 2000, readers of Total Film magazine voted it the 24th greatest comedic film of all time. The film ranked 42nd in the BBC's 2015 list of the 100 greatest American films. The film was selected as the 2nd best comedy of all time in a poll of 253 film critics from 52 countries conducted by the BBC in 2017.

Studio response
Columbia Pictures' early reaction to Dr. Strangelove was anything but enthusiastic. In "Notes From The War Room", in the summer 1994 issue of Grand Street magazine, co-screenwriter Terry Southern recalled that, as production neared the end, "It was about this time that word began to reach us, reflecting concern as to the nature of the film in production. Was it anti-American? Or just anti-military? And the jackpot question: Was it, in fact, anti-American to whatever extent it was anti-military?"

Southern recalled how Kubrick grew concerned about seeming apathy and distancing by studio heads Abe Schneider and Mo Rothman, and by Columbia's characterization of the film as "just a zany, novelty flick which did not reflect the views of the corporation in any way." Southern noted that Rothman was in "prominent attendance" at a ceremony in 1989 when the Library of Congress announced it as one of the first 25 films on the National Film Registry.

Accolades
The film ranked No. 32 on TV Guide's list of the 50 Greatest Movies on TV (and Video).

American Film Institute included the film as #26 in AFI's 100 Years...100 Movies, #3 in AFI's 100 Years...100 Laughs, #64 in AFI's 100 Years...100 Movie Quotes ("Gentlemen, you can't fight in here! This is the War Room!") and #39 in AFI's 100 Years...100 Movies (10th Anniversary Edition).

Canceled sequel
In 1995, Kubrick enlisted Terry Southern to script a sequel titled Son of Strangelove. Kubrick had Terry Gilliam in mind to direct. The script was never completed, but index cards laying out the story's basic structure were found among Southern's papers after he died in October 1995. It was set largely in underground bunkers, where Dr. Strangelove had taken refuge with a group of women.

In 2013, Gilliam commented, "I was told after Kubrick died—by someone who had been dealing with him—that he had been interested in trying to do another Strangelove with me directing. I never knew about that until after he died but I would have loved to."

Stage adaptation
On July 14, 2023, it was announced that a stage adaptation of the film, co-adapted by Armando Iannucci and Sean Foley and starring Steve Coogan will premiere in London's West End in autumn 2024. It will be the first stage adaptation of Kubrick's works.

title: Dr. Strangelove


text:
DNA ligase

DNA ligase is a type of enzyme that facilitates the joining of DNA strands together by catalyzing the formation of a phosphodiester bond. It plays a role in repairing single-strand breaks in duplex DNA in living organisms, but some forms (such as DNA ligase IV) may specifically repair double-strand breaks (i.e. a break in both complementary strands of DNA). Single-strand breaks are repaired by DNA ligase using the complementary strand of the double helix as a template, with DNA ligase creating the final phosphodiester bond to fully repair the DNA.

DNA ligase is used in both DNA repair and DNA replication (see Mammalian ligases). In addition, DNA ligase has extensive use in molecular biology laboratories for recombinant DNA experiments (see Research applications). Purified DNA ligase is used in gene cloning to join DNA molecules together to form recombinant DNA.

Enzymatic mechanism
The mechanism of DNA ligase is to form two covalent phosphodiester bonds between 3' hydroxyl ends of one nucleotide ("acceptor"), with the 5' phosphate end of another ("donor"). Two ATP molecules are consumed for each phosphodiester bond formed. AMP is required for the ligase reaction, which proceeds in four steps:

 * 1) Reorganization of activity site such as nicks in DNA segments or Okazaki fragments etc.
 * 2) Adenylylation (addition of AMP) of a lysine residue in the active center of the enzyme, pyrophosphate is released;
 * 3) Transfer of the AMP to the 5' phosphate of the so-called donor, formation of a pyrophosphate bond;
 * 4) Formation of a phosphodiester bond between the 5' phosphate of the donor and the 3' hydroxyl of the acceptor.

Ligase will also work with blunt ends, although higher enzyme concentrations and different reaction conditions are required.

E. coli
The E. coli DNA ligase is encoded by the lig gene. DNA ligase in E. coli, as well as most prokaryotes, uses energy gained by cleaving nicotinamide adenine dinucleotide (NAD) to create the phosphodiester bond. It does not ligate blunt-ended DNA except under conditions of molecular crowding with polyethylene glycol, and cannot join RNA to DNA efficiently.

The activity of E. coli DNA ligase can be enhanced by DNA polymerase at the right concentrations. Enhancement only works when the concentrations of the DNA polymerase 1 are much lower than the DNA fragments to be ligated. When the concentrations of Pol I DNA polymerases are higher, it has an adverse effect on E. coli DNA ligase

T4
The DNA ligase from bacteriophage T4 (a bacteriophage that infects Escherichia coli bacteria). The T4 ligase is the most-commonly used in laboratory research. It can ligate either cohesive or blunt ends of DNA, oligonucleotides, as well as RNA and RNA-DNA hybrids, but not single-stranded nucleic acids. It can also ligate blunt-ended DNA with much greater efficiency than E. coli DNA ligase. Unlike E. coli DNA ligase, T4 DNA ligase cannot utilize NAD and it has an absolute requirement for ATP as a cofactor. Some engineering has been done to improve the in vitro activity of T4 DNA ligase; one successful approach, for example, tested T4 DNA ligase fused to several alternative DNA binding proteins and found that the constructs with either p50 or NF-kB as fusion partners were over 160% more active in blunt-end ligations for cloning purposes than wild type T4 DNA ligase. A typical reaction for inserting a fragment into a plasmid vector would use about 0.01 (sticky ends) to 1 (blunt ends) units of ligase. The optimal incubation temperature for T4 DNA ligase is 16 °C.

Bacteriophage T4 ligase mutants have increased sensitivity to both UV irradiation and the alkylating agent methyl methanesulfonate indicating that DNA ligase is employed in the repair of the DNA damages caused by these agents.

Mammalian
In mammals, there are four specific types of ligase.
 * 1) DNA ligase 1: ligates the nascent DNA of the lagging strand after the Ribonuclease H has removed the RNA primer from the Okazaki fragments.
 * 2) DNA ligase 3: complexes with DNA repair protein XRCC1 to aid in sealing DNA during the process of nucleotide excision repair and recombinant fragments. Of the all known mammalian DNA ligases, only ligase 3 has been found to be present in mitochondria.
 * 3) DNA ligase 4: complexes with XRCC4.  It catalyzes the final step in the non-homologous end joining DNA double-strand break repair pathway.  It is also required for V(D)J recombination, the process that generates diversity in immunoglobulin and T-cell receptor loci during immune system development.
 * DNA ligase 2: A purification artifact resulting from proteolytic degradation of DNA ligase 3. Initially, it has been recognized as another DNA ligase and it is the reason for the unusual nomenclature of DNA ligases.

DNA ligase from eukaryotes and some microbes uses adenosine triphosphate (ATP) rather than NAD.

Thermostable
Derived from a thermophilic bacterium, the enzyme is stable and active at much higher temperatures than conventional DNA ligases. Its half-life is 48 hours at 65 °C and greater than 1 hour at 95 °C. Ampligase DNA Ligase has been shown to be active for at least 500 thermal cycles (94 °C/80 °C) or 16 hours of cycling.10 This exceptional thermostability permits extremely high hybridization stringency and ligation specificity.

Measurement of activity
There are at least three different units used to measure the activity of DNA ligase:
 * Weiss unit - the amount of ligase that catalyzes the exchange of 1 nmole of 32P from inorganic pyrophosphate to ATP in 20 minutes at 37°C. This is the one most commonly used.
 * Modrich-Lehman unit - this is rarely used, and one unit is defined as the amount of enzyme required to convert 100 nmoles of d(A-T)n to an exonuclease-III resistant form in 30 minutes under standard conditions.
 * Many commercial suppliers of ligases use an arbitrary unit based on the ability of ligase to ligate cohesive ends. These units are often more subjective than quantitative and lack precision.

Research applications
DNA ligases have become indispensable tools in modern molecular biology research for generating recombinant DNA sequences. For example, DNA ligases are used with restriction enzymes to insert DNA fragments, often genes, into plasmids.

Controlling the optimal temperature is a vital aspect of performing efficient recombination experiments involving the ligation of cohesive-ended fragments. Most experiments use T4 DNA Ligase (isolated from bacteriophage T4), which is most active at 37 °C. However, for optimal ligation efficiency with cohesive-ended fragments ("sticky ends"), the optimal enzyme temperature needs to be balanced with the melting temperature Tm of the sticky ends being ligated, the homologous pairing of the sticky ends will not be stable because the high temperature disrupts hydrogen bonding. A ligation reaction is most efficient when the sticky ends are already stably annealed, and disruption of the annealing ends would therefore result in low ligation efficiency. The shorter the overhang, the lower the Tm.

Since blunt-ended DNA fragments have no cohesive ends to anneal, the melting temperature is not a factor to consider within the normal temperature range of the ligation reaction. The limiting factor in blunt end ligation is not the activity of the ligase but rather the number of alignments between DNA fragment ends that occur. The most efficient ligation temperature for blunt-ended DNA would therefore be the temperature at which the greatest number of alignments can occur. The majority of blunt-ended ligations are carried out at 14-25 °C overnight. The absence of stably annealed ends also means that the ligation efficiency is lowered, requiring a higher ligase concentration to be used.

A novel use of DNA ligase can be seen in the field of nano chemistry, specifically in DNA origami. DNA based self-assembly principles have proven useful for organizing nanoscale objects, such as biomolecules, nanomachines, nanoelectronic and photonic component. Assembly of such nano structure requires the creation of an intricate mesh of DNA molecules. Although DNA self-assembly is possible without any outside help using different substrates such as provision of catatonic surface of Aluminium foil, DNA ligase can provide the enzymatic assistance that is required to make DNA lattice structure from DNA over hangs.

History
The first DNA ligase was purified and characterized in 1967 by the Gellert, Lehman, Richardson, and Hurwitz laboratories. It was first purified and characterized by Weiss and Richardson using a six-step chromatographic-fractionation process beginning with elimination of cell debris and addition of streptomycin, followed by several Diethylaminoethyl (DEAE)-cellulose column washes and a final phosphocellulose fractionation. The final extract contained 10% of the activity initially recorded in the E. coli media; along the process it was discovered that ATP and Mg++ were necessary to optimize the reaction. The common commercially available DNA ligases were originally discovered in bacteriophage T4, E. coli and other bacteria.

Disorders
Genetic deficiencies in human DNA ligases have been associated with clinical syndromes marked by immunodeficiency, radiation sensitivity, and developmental abnormalities, LIG4 syndrome (Ligase IV syndrome) is a rare disease associated with mutations in DNA ligase 4 and interferes with dsDNA break-repair mechanisms. Ligase IV syndrome causes immunodeficiency in individuals and is commonly associated with microcephaly and marrow hypoplasia. A list of prevalent diseases caused by lack of or malfunctioning of DNA ligase is as follows.

Xeroderma pigmentosum
Xeroderma pigmentosum, which is commonly known as XP, is an inherited condition characterized by an extreme sensitivity to ultraviolet (UV) rays from sunlight. This condition mostly affects the eyes and areas of skin exposed to the sun. Some affected individuals also have problems involving the nervous system.

Ataxia-telangiectasia
Mutations in the ATM gene cause ataxia–telangiectasia. The ATM gene provides instructions for making a protein that helps control cell division and is involved in DNA repair. This protein plays an important role in the normal development and activity of several body systems, including the nervous system and immune system. The ATM protein assists cells in recognizing damaged or broken DNA strands and coordinates DNA repair by activating enzymes that fix the broken strands. Efficient repair of damaged DNA strands helps maintain the stability of the cell's genetic information. Affected children typically develop difficulty walking, problems with balance and hand coordination, involuntary jerking movements (chorea), muscle twitches (myoclonus), and disturbances in nerve function (neuropathy). The movement problems typically cause people to require wheelchair assistance by adolescence. People with this disorder also have slurred speech and trouble moving their eyes to look side-to-side (oculomotor apraxia).

Fanconi Anemia
Fanconi anemia (FA) is a rare, inherited blood disorder that leads to bone marrow failure. FA prevents bone marrow from making enough new blood cells for the body to work normally. FA also can cause the bone marrow to make many faulty blood cells. This can lead to serious health problems, such as leukemia.

Bloom syndrome
Bloom syndrome results in skin that is sensitive to sun exposure, and usually the development of a butterfly-shaped patch of reddened skin across the nose and cheeks. A skin rash can also appear on other areas that are typically exposed to the sun, such as the back of the hands and the forearms. Small clusters of enlarged blood vessels (telangiectases) often appear in the rash; telangiectases can also occur in the eyes. Other skin features include patches of skin that are lighter or darker than the surrounding areas (hypopigmentation or hyperpigmentation respectively). These patches appear on areas of the skin that are not exposed to the sun, and their development is not related to the rashes.

As a drug target
In recent studies, human DNA ligase I was used in Computer-aided drug design to identify DNA ligase inhibitors as possible therapeutic agents to treat cancer. Since excessive cell growth is a hallmark of cancer development, targeted chemotherapy that disrupts the functioning of DNA ligase can impede adjuvant cancer forms. Furthermore, it has been shown that DNA ligases can be broadly divided into two categories, namely, ATP- and NAD+-dependent. Previous research has shown that although NAD+-dependent DNA ligases have been discovered in sporadic cellular or viral niches outside the bacterial domain of life, there is no instance in which a NAD+-dependent ligase is present in a eukaryotic organism. The presence solely in non-eukaryotic organisms, unique substrate specificity, and distinctive domain structure of NAD+ dependent compared with ATP-dependent human DNA ligases together make NAD+-dependent ligases ideal targets for the development of new antibacterial drugs.

license: Creative Commons - Attribution Share-Alike - https://creativecommons.org/licenses/by-sa/4.0/

title: DNA ligase


text:
Dewey Decimal Classification

The Dewey Decimal Classification (DDC), colloquially known as the Dewey Decimal System, is a proprietary library classification system which allows new books to be added to a library in their appropriate location based on subject. It was first published in the United States by Melvil Dewey in 1876. Originally described in a 44-page pamphlet, it has been expanded to multiple volumes and revised through 23 major editions, the latest printed in 2011. It is also available in an abridged version suitable for smaller libraries. OCLC, a non-profit cooperative that serves libraries, currently maintains the system and licenses online access to WebDewey, a continuously updated version for catalogers.

The decimal number classification introduced the concepts of relative location and relative index. Libraries previously had given books permanent shelf locations that were related to the order of acquisition rather than topic. The classification's notation makes use of three-digit numbers for main classes, with fractional decimals allowing expansion for further detail. Numbers are flexible to the degree that they can be expanded in linear fashion to cover special aspects of general subjects. A library assigns a classification number that unambiguously locates a particular volume in a position relative to other books in the library, on the basis of its subject. The number makes it possible to find any book and to return it to its proper place on the library shelves. The classification system is used in 200,000 libraries in at least 135 countries.

1873–1885: early development
Melvil Dewey (1851–1931) was an American librarian and self-declared reformer. He was a founding member of the American Library Association and can be credited with the promotion of card systems in libraries and business. He developed the ideas for his library classification system in 1873 while working at the Amherst College library. He applied the classification to the books in that library, until in 1876 he had a first version of the classification. In 1876, he published the classification in pamphlet form with the title A Classification and Subject Index for Cataloguing and Arranging the Books and Pamphlets of a Library. He used the pamphlet, published in more than one version during the year, to solicit comments from other librarians. It is not known who received copies or how many commented as only one copy with comments has survived, that of Ernest Cushing Richardson. His classification system was mentioned in an article in the first issue of the Library Journal and in an article by Dewey in the Department of Education publication Public Libraries in America in 1876. In March 1876, he applied for, and received, copyright on the first edition of the index. The edition was 44 pages in length, with 2,000 index entries, and was printed in 200 copies.

1885–1942: period of adoption
The second edition of the Dewey Decimal system, published in 1885 with the title Decimal Classification and Relativ Index for arranging, cataloging, and indexing public and private libraries and for pamflets, clippings, notes, scrap books, index rerums, etc. [sic], comprised 314 pages, with 10,000 index entries. Five hundred copies were produced. Editions 3–14, published between 1888 and 1942, used a variant of this same title. Dewey modified and expanded his system considerably for the second edition. In an introduction to that edition Dewey states that "nearly 100 persons hav [spelling of 'have' per English-language spelling reform, which Dewey championed] contributed criticisms and suggestions".

One of the innovations of the Dewey Decimal system was that of positioning books on the shelves in relation to other books on similar topics. When the system was first introduced, most libraries in the US used fixed positioning: each book was assigned a permanent shelf position based on the book's height and date of acquisition. Library stacks were generally closed to all but the most privileged patrons, so shelf browsing was not considered of importance. The use of the Dewey Decimal system increased during the early 20th century as librarians were convinced of the advantages of relative positioning and of open shelf access for patrons.

New editions were readied as supplies of previously published editions were exhausted, even though some editions provided little change from the previous, as they were primarily needed to fulfill demand. In the next decade, three editions followed closely on: the 3rd (1888), 4th (1891), and 5th (1894). Editions 6 through 11 were published from 1899 to 1922. The 6th edition was published in a record 7,600 copies, although subsequent editions were much lower. During this time, the size of the volume grew, and edition 12 swelled to 1,243 pages, an increase of 25% over the previous edition.

In response to the needs of smaller libraries which were finding the expanded classification schedules difficult to use, in 1894, the first abridged edition of the Dewey Decimal system was produced. The abridged edition generally parallels the full edition, and has been developed for most full editions since that date. By popular request, in 1930, the Library of Congress began to print Dewey Classification numbers on nearly all of its cards, thus making the system immediately available to all libraries making use of the Library of Congress card sets.

Dewey's was not the only library classification available, although it was the most complete. Charles Ammi Cutter published the Expansive Classification in 1882, with initial encouragement from Melvil Dewey. Cutter's system was not adopted by many libraries, with one major exception: it was used as the basis for the Library of Congress Classification system.

In 1895, the International Institute of Bibliography, located in Belgium and led by Paul Otlet, contacted Dewey about the possibility of translating the classification into French, and using the classification system for bibliographies (as opposed to its use for books in libraries). This would have required some changes to the classification, which was under copyright. Dewey gave permission for the creation of a version intended for bibliographies, and also for its translation into French. Dewey did not agree, however, to allow the International Institute of Bibliography to later create an English version of the resulting classification, considering that a violation of their agreement, as well as a violation of Dewey's copyright. Shortly after Dewey's death in 1931, however, an agreement was reached between the committee overseeing the development of the Decimal Classification and the developers of the French Classification Decimal. The English version was published as the Universal Decimal Classification and is still in use today.

According to a study done in 1927, the Dewey system was used in the US in approximately 96% of responding public libraries and 89% of the college libraries. After the death of Melvil Dewey in 1931, administration of the classification was under the Decimal Classification Committee of the Lake Placid Club Education Foundation, and the editorial body was the Decimal Classification Editorial Policy Committee with participation of the American Library Association (ALA), Library of Congress, and Forest Press. By the 14th edition in 1942, the Dewey Decimal Classification index was over 1,900 pages in length and was published in two volumes.

1942–present: forging an identity
The growth of the classification to date had led to significant criticism from medium and large libraries which were too large to use the abridged edition but found the full classification overwhelming. Dewey had intended issuing the classification in three editions: the library edition, which would be the fullest edition; the bibliographic edition, in English and French, which was to be used for the organization of bibliographies rather than of books on the shelf; and the abridged edition. In 1933, the bibliographic edition became the Universal Decimal Classification, which left the library and abridged versions as the formal Dewey Decimal Classification editions. The 15th edition, edited by Milton Ferguson, implemented the growing concept of the "standard edition", designed for the majority of general libraries but not attempting to satisfy the needs of the very largest or of special libraries. It also reduced the size of the Dewey system by over half, from 1,900 to 700 pages. This revision was so radical that an advisory committee was formed right away for the 16th and 17th editions. The 16th and 17th editions, under the editorship of the Library of Congress, grew again to two volumes. However, by then, the Dewey Decimal system had established itself as a classification for general libraries, with the Library of Congress Classification having gained acceptance for large research libraries.

The first electronic version of "Dewey" was created in 1993. Hard-copy editions continue to be issued at intervals; the online WebDewey and Abridged WebDewey are updated quarterly.

Administration and publication
Dewey and a small editorial staff managed the administration of the very early editions. Beginning in 1922, the Lake Placid Club Educational Foundation, a not-for-profit organization founded by Melvil Dewey, managed administrative affairs. The ALA set up a Special Advisory Committee on the Decimal Classification as part of the Cataloging and Classification division of ALA in 1952. The previous Decimal Classification Committee was changed to the Decimal Classification Editorial Policy Committee, with participation of the ALA Division of Cataloging and Classification, and of the Library of Congress.

Melvil Dewey edited the first three editions of the classification system and oversaw the revisions of all editions until his death in 1931. May Seymour became editor in 1891 and served until her death in 1921. She was followed by Dorcas Fellows, who was editor until her death in 1938. Constantin J. Mazney edited the 14th edition. Milton Ferguson functioned as editor from 1949 to 1951. The 16th edition in 1958 was edited under an agreement between the Library of Congress and Forest Press, with David Haykin as director. Editions 16–19 were edited by Benjamin A. Custer and the editor of edition 20 was John P. Comaromi. Joan Mitchell was editor until 2013, covering editions 21 to 23. In 2013 Michael Panzer of OCLC became Editor-in-Chief. The Dewey Editorial Program Manager since 2016 has been Rebecca Green.

Dewey himself held copyright in editions 1 to 6 (1876–1919). Copyright in editions 7–10 was held by the publisher, The Library Bureau. On the death of May Seymour, Dewey conveyed the "copyrights and control of all editions" to the Lake Placid Club Educational Foundation, a non-profit chartered in 1922. The Online Computer Library Center of Dublin, Ohio, US, acquired the trademark and copyrights associated with the Dewey Decimal Classification system when it bought Forest Press in 1988. In 2003 the Dewey Decimal Classification came to the attention of the U.S. press when OCLC sued the Library Hotel for trademark infringement for using the classification system as the hotel theme. The case was settled shortly thereafter.

The OCLC has maintained the classification since 1988, and also publishes new editions of the system. The editorial staff responsible for updates is based partly at the Library of Congress and partly at OCLC. Their work is reviewed by the Decimal Classification Editorial Policy Committee, a ten-member international board which meets twice each year. The four-volume unabridged edition was published approximately every six years, with the last edition (DDC 23) published in mid-2011. In 2017 the editorial staff announced that the English edition of DDC will no longer be printed, in favor of using the frequently updated WebDewey. An experimental version of Dewey in RDF was previously available at dewey.info beginning in 2009, but has not been available since 2015.

In addition to the full version, a single-volume abridged edition designed for libraries with 20,000 titles or fewer has been made available since 1895. The last printed English abridged edition, Abridged Edition 15, was published in early 2012.

Design
The Dewey Decimal Classification organizes library materials by discipline or field of study. The scheme comprises ten classes, each divided into ten divisions, each having ten sections. The system's notation uses Indo-Arabic numbers, with three whole numbers making up the main classes and sub-classes and decimals designating further divisions. The classification structure is hierarchical and the notation follows the same hierarchy. Libraries not needing the full level of detail of the classification can trim right-most decimal digits from the class number to obtain more general classifications. For example:

 * 500 Natural sciences and mathematics
 * 510 Mathematics
 * 516 Geometry
 * 516.3 Analytic geometries
 * 516.37 Metric differential geometries
 * 516.375 Finsler geometry

The classification was originally enumerative, meaning that it listed all of the classes explicitly in the schedules. Over time it added some aspects of a faceted classification scheme, allowing classifiers to construct a number by combining a class number for a topic with an entry from a separate table. Tables cover commonly used elements such as geographical and temporal aspects, language, and bibliographic forms. For example, a class number could be constructed using 330 for economics + .9 for geographic treatment + .04 for Europe to create the class 330.94 European economy. Or one could combine the class 973 (for the United States) + .05 (for periodical publications on the topic) to arrive at the number 973.05 for periodicals concerning the United States generally. The classification also makes use of mnemonics in some areas, such that the number 5 represents the country Italy in classification numbers like 945 (history of Italy), 450 (Italian language), and 195 (Italian philosophy). The combination of faceting and mnemonics makes the classification synthetic in nature, with meaning built into parts of the classification number.

The Dewey Decimal Classification has a number for all subjects, including fiction, although many libraries maintain a separate fiction section shelved by alphabetical order of the author's surname. Each assigned number consists of two parts: a class number (from the Dewey system) and a book number, which "prevents confusion of different books on the same subject". A common form of the book number is called a Cutter number, which represents the author and distinguishes the book from other books on the same topic.

Classes
(From DDC 23 )
 * 000 – Computer science, information and general works
 * 100 – Philosophy and psychology
 * 200 – Religion
 * 300 – Social sciences
 * 400 – Language
 * 500 – Pure science
 * 600 – Technology
 * 700 – Arts and recreation
 * 800 – Literature
 * 900 – History and geography

Tables
(From DDC 23 )
 * T1 Standard Subdivisions
 * T2 Geographic Areas, Historical Periods, Biography
 * T3 Subdivisions for the Arts, for Individual Literatures, for Specific Literary Forms
 * T3A Subdivisions for Works by or about Individual Authors
 * T3B Subdivisions for Works by or about More than One Author
 * T3C Notation to Be Added Where Instructed in Table 3B, 700.4, 791.4, 808–809
 * T4 Subdivisions of Individual Languages and Language Families
 * T5 Ethnic and National Groups
 * T6 Languages

Relative Index
The Relative Index (or, as Dewey spelled it, "Relativ Index") is an alphabetical index to the classification, for use both by classifiers and by library users when seeking books by topic. The index was "relative" because the index entries pointed to the class numbers, not to the page numbers of the printed classification schedule. In this way, the Dewey Decimal Classification itself had the same relative positioning as the library shelf and could be used either as an entry point to the classification, by catalogers, or as an index to a Dewey-classed library itself.

Influence and criticism
Dewey Decimal Classification numbers formed the basis of the Universal Decimal Classification (UDC), which combines the basic Dewey numbers with selected punctuation marks (comma, colon, parentheses, etc.). Adaptations of the system for specific regions outside the English-speaking world include the Korean Decimal Classification, the New Classification Scheme for Chinese Libraries, and the Nippon Decimal Classification in Japan.

Despite its widespread use, the classification has been criticized for its complexity and its limited capability for amendment. In particular, the arrangement of subheadings has been described as archaic and biased towards an Anglo-American world view. This is particularly clear in the 800s section, in which most literature, particularly from outside the United States or Europe, is relegated to the 890s particularly when contrasted with the 900s—history. In 2007–08, the Maricopa County Library District in Arizona abandoned the DDC in favor of the Book Industry Standards and Communications (BISAC) system commonly used by commercial bookstores, in an effort to make its libraries more accessible for their users. Several other libraries across the United States and other countries (including Canada and the Netherlands) followed suit.

Treatment of homosexuality
In 1932, topics relating to homosexuality were first added to the system under 132 (mental derangements) and 159.9 (abnormal psychology). In 1952, homosexuality was also included under 301.424 (the study of sexes in society). In 1989, it was added to 363.49 (social problems), a classification that continues in the current edition.

In 1996, homosexuality was added to 306.7 (sexual relations); this remains the preferred location in the current edition. Although books can also be found under 616.8583 (sexual practices viewed as medical disorders), the official direction states: "Use 616.8583 for homosexuality only when the work treats homosexuality as a medical disorder, or focuses on arguing against the views of those who consider homosexuality to be a medical disorder."

Treatment of religion
The top-level class for religion heavily favors Christianity, dedicating nearly all of the 200 division to it: the world's thousands of other religions were listed under the 290s. For example, Islam is under just DDC 297, despite being almost as large as Christianity by population. The entire 200 section has remained largely unchanged since DDC 1, since restructuring would pose a significant amount of work for existing libraries. The motivation for this change is ideological rather than technical, as appending significant figures can add space as needed.

Treatment of women
It has also been argued by Hope A. Olson that the placement of topics related to women shows implicit bias, but this has been simpler to address than the religion schema. Some changes made so far have been in numerical proximity, altering the placement of topics relative to each other. For example, in older versions of the DDC, some categories regarding women were adjacent to categories on etiquette; the placement of these categories next to each other imposed an association of etiquette with women, rather than treating it as gender-neutral. This was changed in DDC version 17, in 1965.

title: Dewey Decimal Classification


text:
Duḥkha

Duḥkha (Sanskrit: दुःख; Pali: dukkha), 'unease', "standing unstable," commonly translated as "suffering", "pain", or "unhappiness", is an important concept in Buddhism, Jainism and Hinduism. Its meaning depends on the context, and may refer more specifically to the "unsatisfactoriness" or "unease" of mundane life, not being at ease when driven by craving/grasping and ignorance.

While the term dukkha has often been derived from the prefix du ("bad" or "difficult") and the root kha ("empty," "hole"), meaning a badly fitting axle-hole of a cart or chariot giving "a very bumpy ride," it may actually be derived from duḥ-stha, a "dis-/ bad- + stand-", that is, "standing badly, unsteady," "unstable."

In Buddhism, dukkha is part of the first of the Four Noble Truths and one of the three marks of existence. The term also appears in scriptures of Hinduism, such as the Upanishads, in discussions of moksha (spiritual liberation).

Etymology and meaning
Duḥkha (Sanskrit: दुःख; Pali: dukkha) is a term found in the Upanishads and Buddhist texts, meaning anything that is "uneasy, uncomfortable, unpleasant, difficult, causing pain or sadness". It is also a concept in Indian religions about the nature of life that innately includes the "unpleasant", "suffering", "pain", "sorrow", "distress", "grief" or "misery." The term duḥkha does not have a one-word English translation, and embodies diverse aspects of unpleasant human experiences. It is often understood as the opposite of sukha, meaning "happiness," "comfort" or "ease."

Axle hole
The word has been explained in recent times as a derivation from Aryan terminology for an axle hole, referring to an axle hole which is not in the center and leads to a bumpy, uncomfortable ride. According to Winthrop Sargeant, "The ancient Aryans who brought the Sanskrit language to India were a nomadic, horse- and cattle-breeding people who travelled in horse- or ox-drawn vehicles. Su and dus are prefixes indicating good or bad. The word kha, in later Sanskrit meaning 'sky,' 'ether,' or 'space,' was originally the word for 'hole,' particularly an axle hole of one of the Aryan's vehicles. Thus sukha ... meant, originally, 'having a good axle hole,' while duhkha meant 'having a poor axle hole,' leading to discomfort."

Joseph Goldstein, American vipassana teacher and writer, explains the etymology as follows: "The word dukkha is made up of the prefix du and the root kha. Du means 'bad' or 'difficult'. Kha means 'empty'. 'Empty', here, refers to several things—some specific, others more general. One of the specific meanings refers to the empty axle hole of a wheel. If the axle fits badly into the center hole, we get a very bumpy ride. This is a good analogy for our ride through saṃsāra."

'Standing unstable'
However, according to Monier Monier-Williams, the actual roots of the Pali term dukkha appear to be Sanskrit दुस्- (dus-, "bad") + स्था (stha, "to stand"). Regular phonological changes in the development of Sanskrit into the various Prakrits led to a shift from dus-sthā to duḥkha to dukkha.

Analayo concurs, stating that dukkha as derived from duh-stha, "standing badly," "conveys nuances of "uneasiness" or of being "uncomfortable." Silk Road philologist Christopher I. Beckwith elaborates on this derivation. According to Beckwith: "...although the sense of duḥkha in Normative Buddhism is traditionally given as 'suffering', that and similar interpretations are highly unlikely for Early Buddhism. Significantly, Monier-Williams himself doubts the usual explanation of duḥkha and presents an alternative one immediately after it, namely: duḥ-stha "'standing badly,' unsteady, disquieted (lit. and fig.); uneasy", and so on. This form is also attested, and makes much better sense as the opposite of the Rig Veda sense of sukha, which Monier-Williams gives in full."

Translation
The literal meaning of duhkha, as used in a general sense is "suffering" or "painful." Its exact translation depends on the context. Contemporary translators of Buddhist texts use a variety of English words to convey the aspects of dukh. Early Western translators of Buddhist texts (before the 1970s) typically translated the Pali term dukkha as "suffering." Later translators have emphasized that "suffering" is a too limited translation for the term duḥkha, and have preferred to either leave the term untranslated, or to clarify that translation with terms such as anxiety, distress, frustration, unease, unsatisfactoriness, not having what one wants, having what one doesn't want, etc. In the sequence "birth is painful," dukhka may be translated as "painful." When related to vedana, "feeling," dukkha ("unpleasant," "painful") is the opposite of sukkha ("pleasure," "pleasant"), yet all feelings are dukkha in that they are impermanent, conditioned phenomena, which are unsatisfactory, incapable of providing lasting satisfaction. The term "unsatisfactoriness" then is often used to emphasize the unsatisfactoriness of "life under the influence of afflictions and polluted karma."

Early Buddhism
Duḥkha is one of the three marks of existence, namely anitya ("impermanent"), duḥkha ("unsatisfactory"), anatman (without a lasting essence).

Within the Buddhist sutras, duḥkha has a broad meaning, and is divided in three categories:
 * Dukkha-dukkha, aversion to physical suffering – this includes the physical and mental sufferings of birth, aging, illness, dying; distress due to what is not desirable.
 * Viparinama-dukkha, the frustration of disappearing happiness – this is the duḥkha of pleasant or happy experiences changing to unpleasant when the causes and conditions that produced the pleasant experiences cease.
 * Sankhara-dukkha, the unsatisfactoriness of changing and impermanent "things" – the incapability of conditioned things to give us lasting happiness. This includes "a basic unsatisfactoriness pervading all existence, all forms of life, because all forms of life are changing, impermanent and without any inner core or substance." On this level, the term indicates a lack of lasting satisfaction, or a sense that things never measure up to our expectations or standards.

Various sutras sum up how life in this "mundane world" is regarded to be duḥkha, starting with saṃsāra, the ongoing process of death and rebirth itself:
 * 1) Birth is duḥkha, maturation is duhkha, aging is duḥkha, illness is duḥkha, death is duḥkha;
 * 2) Sorrow, lamentation, pain, grief, and despair are duḥkha;
 * 3) Association with the unbeloved is duḥkha; separation from the loved is duḥkha;
 * 4) Not getting what is wanted is duḥkha.
 * 5) In conclusion, the five clinging-aggregates are duḥkha.

Early emphasis is on the importance of developing insight into the nature of duḥkha, the conditions that cause it, and how it can be overcome. This process is formulated in the teachings on the Four Noble Truths.

Chinese Buddhism
Chinese Buddhist tradition has been influenced by Taoism and Confucian theory that advocates that duhkha (古:十Ten directions, 口 hole or opening) is associated to the theory of seven emotions of endogenous disease through the formation of the spirit of the po a term that relates to the Western psychological notion of ego or the theological reference to the human soul. This theory is expounded in the application of traditional Chinese medicine for the treatment and prevention of pain and suffering from illness, disease and ignorance.

Literal suffering and awakening
Awakening, that is, awakening to one's true mind of emptiness and compassion, does not necessarily end physical suffering. In the Buddhist tradition, suffering after awakening is often explained as the working-out or untangling of karma of one's previous present life.

Hinduism
In Hinduism, duḥkha encompasses many meanings such as the phenomenological senses of pain and grief, a deep-seated dissatisfaction with the limitations of worldly existence, and the devastation of impermanence.

In Hindu scriptures, the earliest Upaniads — the Brihadaranyaka Upanishad and the Chandogya Upanishad — in all likelihood predate the advent of Buddhism. In these scriptures of Hinduism, the Sanskrit word dukha (दुःख) appears in the sense of "suffering, sorrow, distress", and in the context of a spiritual pursuit and liberation through the knowledge of Atman (soul/self).

The verse 4.4.14 of the states:

The verse 7.26.2 of the states:

The concept of sorrow and suffering, and self-knowledge as a means to overcome it, appears extensively with other terms in the pre-Buddhist Upanishads. The term Duhkha also appears in many other middle and later post-Buddhist Upanishads such as the verse 6.20 of Shvetashvatara Upanishad, as well as in the Bhagavad Gita, all in the contexts of moksha and bhakti.

Verse 2.56 of the Bhagavad Gita states:

And verse 8.15 of the Bhagavad Gita states:

The term also appears in the foundational Sutras of the six schools of Hindu philosophy, such as the opening lines of Samkhya karika of the Samkhya school. The Samkhya school identifies three types of suffering. The Yoga Sutras of Patanjali state that "for one who has discrimination, everything is suffering" (duḥkham eva sarvaṁ vivekinaḥ).

Jainism
Duḥkha is explained in the Tattvartha Sutra, an authoritative Jain scripture from the 2nd century.

title: Duḥkha


text:
Darwin Awards

The Darwin Awards are a rhetorical tongue-in-cheek honor that originated in Usenet newsgroup discussions around 1985. They recognize individuals who have supposedly contributed to human evolution by selecting themselves out of the gene pool by dying or becoming sterilized by their own actions.

The project became more formalized with the creation of a website in 1993, followed by a series of books starting in 2000 by Wendy Northcutt. The criterion for the awards states: "In the spirit of Charles Darwin, the Darwin Awards commemorate individuals who protect our gene pool by making the ultimate sacrifice of their own lives. Darwin Award winners eliminate themselves in an extraordinarily idiotic manner, thereby improving our species' chances of long-term survival."

Accidental self-sterilization also qualifies, but the site notes: "Of necessity, the award is usually bestowed posthumously." The candidate is disqualified, though, if "innocent bystanders" are killed in the process, as they might have contributed positively to the gene pool. The logical problem presented by award winners who may have already reproduced is not addressed in the selection process owing to the difficulty of ascertaining whether or not a person has children; the Darwin Award rules state that the presence of offspring does not disqualify a nominee.

History
The origin of the Darwin Awards can be traced back to posts on Usenet group discussions as early as 1985. A post on August 7, 1985 describes the awards as being "given posthumously to people who have made the supreme sacrifice to keep their genes out of our pool. Style counts, not everyone who dies from their own stupidity can win." This early post cites an example of a person who tried to break into a vending machine and was crushed to death when he pulled it over himself. Another widely distributed early story mentioning the Darwin Awards is the JATO Rocket Car, which describes a man who strapped a jet-assisted take-off unit to his Chevrolet Impala in the Arizona desert and who died on the side of a cliff as his car achieved speeds of 250 to 300 mph. This story was later determined to be an urban legend by the Arizona Department of Public Safety. Wendy Northcutt says the official Darwin Awards website run by Northcutt does its best to confirm all stories submitted, listing them as, "confirmed true by Darwin". Many of the viral emails circulating the Internet, however, are hoaxes and urban legends.

The website and collection of books were started in 1993 by Wendy Northcutt, who at the time was a graduate in molecular biology from the University of California, Berkeley. She went on to study neurobiology at Stanford University, doing research on cancer and telomerase. In her spare time, she organised chain letters from family members into the original Darwin Awards website hosted in her personal account space at Stanford. She eventually left the bench in 1998 and devoted herself full-time to her website and books in September 1999. By 2002, the website received 7 million page hits per month.

Northcutt encountered some difficulty in publishing the first book, since most publishers would only offer her a deal if she agreed to remove the stories from the Internet, but she refused: "It was a community! I could not do that. Even though it might have cost me a lot of money, I kept saying no." She eventually found a publisher who agreed to print a book containing only 10% of the material gathered for the website. The first book turned out to be a success, and was listed on The New York Times best-seller list for 6 months.

Not all of the feedback from the stories Northcutt published was positive, and she occasionally received email from people who knew the deceased. One such person advised: "This is horrible. It has shocked our community to the core. You should remove this." Northcutt demurred: "I can't. It's just too stupid." Northcutt kept the stories on the website and in her books, citing them as a "funny-but-true safety guide", and mentioning that children who read the book are going to be much more careful around explosives.

The website also awards Honorable Mentions to individuals who survive their misadventures with their reproductive capacity intact. One example of this is Larry Walters, who attached helium-filled weather balloons to a lawn chair and floated far above Long Beach, California, in July 1982. He reached an altitude of 16000 ft, but survived, to be later fined for crossing controlled airspace. (Walters later fell into depression and committed suicide.) Another notable honorable mention was given to the two men who attempted to burgle the home of footballer Duncan Ferguson (who had an infamous reputation for physical aggression on and off the pitch, including four convictions for assault and who had served six months in Glasgow's Barlinnie Prison) in 2001, with one burglar requiring three days' hospitalisation after being confronted by the player.

A 2014 study published in the British Medical Journal found that between 1995 and 2014, males represented 88.7% of Darwin Award winners (see figure).

The comedy film The Darwin Awards (2006), written and directed by Finn Taylor, was based on the website and many of the Darwin Awards stories.

Rules
Northcutt has stated five requirements for a Darwin Award:

Nominee must be dead or rendered sterile
This may be subject to dispute. Potential awardees may be out of the gene pool because of age; others have already reproduced before their deaths. To avoid debates about the possibility of in vitro fertilization, artificial insemination, or cloning, the original Darwin Awards book applied the following "deserted island" test to potential winners: If the person were unable to reproduce when stranded on a deserted island with a fertile member of the opposite sex, he or she would be considered sterile. Winners of the award, in general, either are dead or have become unable to use their sexual organs.

Astoundingly stupid judgment
The candidate's foolishness must be unique and sensational, likely because the award is intended to be funny. A number of foolish but common activities, such as smoking in bed, are excluded from consideration. In contrast, self-immolation caused by smoking after being administered a flammable ointment in a hospital and specifically told not to smoke is grounds for nomination. One "Honorable Mention" (a man who attempted suicide by swallowing nitroglycerine pills, and then tried to detonate them by running into a wall) is noted to be in this category, despite being intentional and self-inflicted (i.e. attempted suicide), which would normally disqualify the inductee.

Cause of one's own demise
Killing a friend with a hand grenade would not be eligible, but killing oneself while manufacturing a homemade chimney-cleaning device from a grenade would be. To earn a Darwin Award, one must have killed oneself, or rendered oneself sterile; merely causing death to a third party is insufficient.

Capable of sound judgment
The nominee must be at least past the legal driving age and free of mental defect (Northcutt considers injury or death caused by mental defect to be tragic, rather than amusing, and routinely disqualifies such entries). After much discussion, a small category regarding deaths below this age limit also exists. Entry into this category requires that the peers of the candidate be of the opinion that the actions of the person in question were above and beyond the limits of reason.

In 2011, however, the awards targeted a 16-year-old boy in Leeds who died stealing copper wiring (the standard minimum driving age in Great Britain being 17). In 2012, Northcutt made similar light of a 14-year-old girl in Brazil who was killed while leaning out of a school bus window, but she was "disqualified" for the award itself because of the likely public objection owing to the girl's age, which Northcutt asserts is based on "magical thinking".

Event must be verified
The story must be documented by reliable sources: e.g., reputable newspaper articles, confirmed television reports, or responsible eyewitnesses. If a story is found to be untrue, it is disqualified, but particularly amusing ones are placed in the urban legend section of the archives. Despite this requirement, many of the stories are fictional, often appearing as "original submissions" and presenting no further sources than unverified "eyewitnesses". Most such stories on Northcutt's Darwin Awards site are filed in the Personal Accounts section.

Informal rules
In addition, later revisions to the qualification criteria add several requirements that have not been made into formalized "rules":
 * Innocent bystanders cannot be endangered.
 * The qualifying event must be caused without deliberate intent to end the nominee's own life (or fertility). (To discourage notoriety-seekers from injuring themselves purposely to win a Darwin.)

Reception
The Darwin Awards have received varying levels of scrutiny from the scientific community. In his book Encyclopedia of Evolution, biology professor Stanley A. Rice comments: "Despite the tremendous value of these stories as entertainment, it is unlikely that they represent evolution in action", citing the nonexistence of "judgment impairment genes". On an essay in the book The Evolution of Evil, professor Nathan Hallanger acknowledges that the Darwin Awards are meant as black humor, but associates them with the eugenics movement of the early 20th century. University of Oxford biophysicist Sylvia McLain, writing for The Guardian, says that while the Darwin Awards are "clearly meant to be funny", they do not accurately represent how genetics work, further noting that "'smart' people do stupid things all the time". Geologist and science communicator Sharon A. Hill has criticized the Darwin Awards on both scientific and ethical grounds, claiming that no genetic traits impact personal intelligence or good judgment to be targeted by natural selection, and calling them an example of "ignorance" and "heartlessness".

Notable recipients

 * The driver of the JATO Rocket Car in the well-known urban legend.
 * Garry Hoy who fell from the 24th story of the Toronto-Dominion Centre whilst attempting to demonstrate to a group of students that the windows were unbreakable. His death has been featured in television programs such as 1000 Ways to Die and MythBusters.
 * Charles Stephens, the first person to die while attempting to go over Niagara Falls in a barrel.
 * Larry Walters was awarded an 'Honorable Mention' for his lawn chair balloon flight into controlled airspace.
 * John Allen Chau who, supposedly on his own behalf, tried to convert an isolated indigenous group on North Sentinel Island to Christianity, and was killed by them.

title: Darwin Awards