text:
Adenine

Adenine (symbol A or Ade) is a  purine nucleobase. It is one of the four nucleobases in the nucleic acids of DNA, the other three being guanine (G), cytosine (C), and thymine (T). Adenine derivatives have various roles in biochemistry including cellular respiration, in the form of both the energy-rich adenosine triphosphate (ATP) and the cofactors nicotinamide adenine dinucleotide (NAD), flavin adenine dinucleotide (FAD) and Coenzyme A. It also has functions in protein synthesis and as a chemical component of DNA and RNA. The shape of adenine is complementary to either thymine in DNA or uracil in RNA.

The adjacent image shows pure adenine, as an independent molecule. When connected into DNA, a covalent bond is formed between deoxyribose sugar and the bottom left nitrogen (thereby removing the existing hydrogen atom). The remaining structure is called an adenine residue, as part of a larger molecule. Adenosine is adenine reacted with ribose, as used in RNA and ATP; Deoxyadenosine is adenine attached to deoxyribose, as used to form DNA.

Structure
Adenine forms several tautomers, compounds that can be rapidly interconverted and are often considered equivalent. However, in isolated conditions, i.e. in an inert gas matrix and in the gas phase, mainly the 9H-adenine tautomer is found.

Biosynthesis
Purine metabolism involves the formation of adenine and guanine. Both adenine and guanine are derived from the nucleotide inosine monophosphate (IMP), which in turn is synthesized from a pre-existing ribose phosphate through a complex pathway using atoms from the amino acids glycine, glutamine, and aspartic acid, as well as the coenzyme tetrahydrofolate.

Manufacturing method
Patented Aug. 20, 1968, the current recognized method of industrial-scale production of adenine is a modified form of the formamide method. This method heats up formamide under 120 degree Celsius conditions within a sealed flask for 5 hours to form adenine. The reaction is heavily increased in quantity by using a phosphorus oxychloride (phosphoryl chloride) or phosphorus pentachloride as an acid catalyst and sunlight or ultraviolet conditions. After the 5 hours have passed and the formamide-phosphorus oxychloride-adenine solution cools down, water is put into the flask containing the formamide and now-formed adenine. The water-formamide-adenine solution is then poured through a filtering column of activated charcoal. The water and formamide molecules, being small molecules, will pass through the charcoal and into the waste flask; the large adenine molecules, however, will attach or "adsorb" to the charcoal due to the van der Waals forces that interact between the adenine and the carbon in the charcoal. Because charcoal has a large surface area, it's able to capture the majority of molecules that pass a certain size (greater than water and formamide) through it. To extract the adenine from the charcoal-adsorbed adenine, ammonia gas dissolved in water (aqua ammonia) is poured onto the activated charcoal-adenine structure to liberate the adenine into the ammonia-water solution. The solution containing water, ammonia, and adenine is then left to air dry, with the adenine losing solubility due to the loss of ammonia gas that previously made the solution basic and capable of dissolving adenine, thus causing it to crystallize into a pure white powder that can be stored.

Function
Adenine is one of the two purine nucleobases (the other being guanine) used in forming nucleotides of the nucleic acids. In DNA, adenine binds to thymine via two hydrogen bonds to assist in stabilizing the nucleic acid structures. In RNA, which is used for protein synthesis, adenine binds to uracil.

Adenine forms adenosine, a nucleoside, when attached to ribose, and deoxyadenosine when attached to deoxyribose. It forms adenosine triphosphate (ATP), a nucleoside triphosphate, when three phosphate groups are added to adenosine. Adenosine triphosphate is used in cellular metabolism as one of the basic methods of transferring chemical energy between chemical reactions. ATP is thus a derivative of adenine, adenosine, cyclic adenosine monophosphate, and adenosine diphosphate.

 * {| class="wikitable left" style="text-align:center"

 * Adenosin.svg
 * Desoxyadenosin.svg
 * Adenosine, A
 * Deoxyadenosine, dA
 * }
 * Deoxyadenosine, dA
 * }

History
In older literature, adenine was sometimes called Vitamin B4. Due to it being synthesized by the body and not essential to be obtained by diet, it does not meet the definition of vitamin and is no longer part of the Vitamin B complex. However, two B vitamins, niacin and riboflavin, bind with adenine to form the essential cofactors nicotinamide adenine dinucleotide (NAD) and flavin adenine dinucleotide (FAD), respectively. Hermann Emil Fischer was one of the early scientists to study adenine.

It was named in 1885 by Albrecht Kossel after Greek ἀδήν aden "gland", in reference to the pancreas, from which Kossel's sample had been extracted.

Experiments performed in 1961 by Joan Oró have shown that a large quantity of adenine can be synthesized from the polymerization of ammonia with five hydrogen cyanide (HCN) molecules in aqueous solution; whether this has implications for the origin of life on Earth is under debate.

On August 8, 2011, a report, based on NASA studies with meteorites found on Earth, was published suggesting building blocks of DNA and RNA (adenine, guanine and related organic molecules) may have been formed extraterrestrially in outer space. In 2011, physicists reported that adenine has an "unexpectedly variable range of ionization energies along its reaction pathways" which suggested that "understanding experimental data on how adenine survives exposure to UV light is much more complicated than previously thought"; these findings have implications for spectroscopic measurements of heterocyclic compounds, according to one report.

title: Adenine


text:
1192

Year 1192 (MCXCII) was a leap year starting on Wednesday (link will display the full calendar) of the Julian calendar, the 1192nd year of the Common Era (CE) and Anno Domini (AD) designations, the 192nd year of the 2nd millennium, the 92nd year of the 12th century, and the 3rd year of the 1190s decade.

Events

 * January 7 – Venus occults Jupiter.
 * April 28 – Conrad of Montferrat (Conrad I), King of Jerusalem, is assassinated in Tyre, only days after his title to the throne is confirmed by election. The killing is carried out by Hashshashin, later the basis of folk etymology for the English word "assassin."
 * August 21 – Minamoto no Yoritomo is granted the title of shōgun, thereby officially establishing the first shogunate in the history of Japan.
 * Margaritus of Brindisi is created the first Count of Malta for capturing Constance, Holy Roman Empress in 1191.
 * Second Battle of Tarain in India: The Ghurid forces of Mu'izz al-Din are victorious over Prithviraj Chauhan.
 * The Lugouqiao (later the Marco Polo) Bridge is completed in Beijing.
 * Constance, Holy Roman Empress is released by Tancred, King of Sicily under the pressure of Pope Celestine III in May, and returns to Germany in June.
 * Prince Yaroslav Vladimirovich of Novgorod burns down Tartu and Otepää Castles, in Estonia.

The Third Crusade

 * August 5 – Battle of Jaffa: Richard I of England defeats the forces of Saladin and ends hostilities, paving the way for a truce.
 * September 2 – After negotiations between Richard and Saladin, the Treaty of Jaffa is signed, which makes sure Jerusalem remains in Muslim hands, but insures visiting rights for pilgrims to come to the Holy City. The Third Crusade ends.
 * October 9 – Richard leaves the Holy Land, setting sail from Acre and beginning his return to Europe.
 * December 11 – Returning from the Third Crusade, Richard I of England is taken prisoner by Leopold V, Duke of Austria, and secured at Dürnstein.

Births

 * September 17 – Minamoto no Sanetomo, Japanese shōgun (d. 1219)
 * Queen Maria of Jerusalem (d. 1212)
 * King Stefan Radoslav of Serbia (d. 1234)
 * Saint Syed Jalaluddin Bukhari of Uch Sharif (d. 1291)

Deaths

 * April 26 – Emperor Go-Shirakawa of Japan (b. 1127)
 * April 28 – Conrad of Montferrat, King of Jerusalem (b. mid-1140s)
 * May 8 – Duke Ottokar IV, Duke of Styria (b. 1163)
 * August 25 – Hugh III, Duke of Burgundy (b. 1142)
 * Saint Margaret of England, English saint
 * Ikhtiyar al-Din Hasan ibn Ghafras, vizier of the Sultanate of Rum
 * Kilij Arslan II, Sultan of Rum
 * Rashid ad-Din Sinan, the "Old Man of the Mountain", leader of the Hashashin sect (b. 1132/1135)
 * Prithviraj Chauhan, King of the Chauhan Dynasty (b. 1166)

license: Creative Commons - Attribution Share-Alike - https://creativecommons.org/licenses/by-sa/4.0/

title: 1192


text:
1158

Year 1158 (MCLVIII) was a common year starting on Wednesday (link will display the full calendar) of the Julian calendar.

Byzantine Empire

 * Autumn – Emperor Manuel I Komnenos sets out from Constantinople at the head of an expeditionary army. He marches to Cilicia; and while the main army follows the coast road eastwards Manuel hurries ahead with a force of only 500 cavalry. He manages to surprise Thoros II "the Great", lord of the Armenian Kingdom of Cilicia, who participated in the attack on Cyprus in 1156. Thoros flees into the mountains and Cilicia is occupied by the Byzantines.

Europe

 * January 11 – Vladislav II becomes king of Bohemia. He is crowned by Frederick Barbarossa, Holy Roman Emperor, with a diadem (called by the chroniclers a diadema or circulus). Vladislaus is also invested with Upper Lusatia, and accompanies Frederick to Milan to suppress the rebellion in Lombardy (northern Italy).
 * The Diet of Roncaglia is convoked by Frederick I. He mobilises an army of 100,000 men and leaves in June for a second Italian expedition – accompanied by Henry the Lion and his Saxon forces. He crosses the Alps and lays siege to Milan. German forces capture the city from the rebels after a short siege. However Milan soon rebels again, with Empress Beatrice taken captive and forced into parading on a donkey.
 * Summer – King Henry II of England travels to France to meet King Louis VII and propose a marriage between his three-year-old son Henry and Louis' daughter Margaret (less than a year old). She is shipped to England, as the future wife and queen. The Vexin region is promised to Margaret as dowry and is put under the care of the Knights Templar, until her future husband is old enough to take control of it.
 * August 31 – King Sancho III ("the Desired") dies after a 1-year reign. He is succeeded as ruler of Castile by his 2-year-old son Alfonso VIII ("the Noble"). The noble houses of Lara and Castro claim the regency, as the boy's uncle, Ferdinand II (ruler of León and Galicia).
 * Raymond of Fitero, Spanish monk and abbot, pledges to defend the fortress of Calatrava (guarding the roads to Córdoba and Toledo) from incoming Muslim raiders. It is the founding moment of the Order of Calatrava, the spearhead of the Iberian armies during the Reconquista.
 * Portuguese forces, led by King Afonso I of Portugal ("the Great"), conquer Pamela, Alcácer do Sal and Sesimbra from the diminished Almoravids.
 * 12-year-old William Marshal is sent from Englan to the Château de Tancarville in Normandy to be brought up in the household of William de Tancarville, a cousin of William's mother. He begins his training as a knight, this also includes academic studies, practical lessons in chivalry and courtly life, and warfare and combat (using wooden swords and spears).
 * Welsh forces under Ifor Bach ("Ivor the Short") attack Cardiff Castle and kidnap William Fitz Robert, Norman lord of Glamorgan, along with his family.

Asia

 * September 5 – Emperor Go-Shirakawa of Japan abdicates the throne after a 3-year reign. He is succeeded by his 15-year-old son Nijō as the 77th emperor. Go-Shirakawa retains power, and gives Kiyomori Taira a higher position to lead a samurai-dominated government.

Economy

 * To restore confidence in the English currency, Henry II mints a new penny (known to specialists as the Tealby penny) with his own image.

Education

 * The University of Bologna is granted its first privileges by Frederick I.

Religion

 * The Roman Catholic Diocese of Derry is founded in Ireland.

Births

 * August 6 – Al-Nasir li-Din Allah, Abbasid caliph (d. 1225)
 * September 23 – Geoffrey II, duke of Brittany (d. 1186)
 * Albert I ("the Proud"), margrave of Meissen (d. 1195)
 * Baldwin of Bethune, French nobleman (d. 1212)
 * Ermengol VIII (or Armengol), count of Urgell (d. 1208)
 * Fujiwara no Ietaka, Japanese waka poet (d. 1237)
 * Giordano Forzatè, Italian religious leader (d. 1248)
 * Henry I, Count of Bar, French nobleman and knight (d. 1190)
 * Henry I, Duke of Mödling ("the Elder"), German nobleman (d. 1223)
 * Jinul (or Chinul), Korean Zen master (d. 1210)
 * Margaret of France, Queen of England and Hungary, daughter of Louis VII of France (d. 1197)
 * Philip of Dreux, bishop of Beauvais (d. 1217)
 * Satō Tsugunobu, Japanese warrior (d. 1185)
 * Taira no Shigehira, Japanese general (d. 1185)
 * Theobald I, Count of Bar, French nobleman and knight (d. 1214)
 * Valdemar Knudsen, Danish bishop (d. 1236)
 * Yvette of Huy, Belgian anchoress (d. 1228)

Deaths

 * April 26 – Martirius, archbishop of Esztergom
 * July 19 – Wibald, German monk and abbot (b. 1098)
 * July 27 – Geoffrey VI, count of Nantes (b. 1134)
 * August 20 – Rögnvald Kali Kolsson, Earl of Orkney
 * August 31 – Sancho III, king of Castile (b. 1134)
 * September 22 – Otto of Freising, German bishop (b. 1114)
 * December 15 – Frederick II, German archbishop
 * Abu Jafar ibn Atiyya, Almohad vizier and writer
 * Anselm of Havelberg, German bishop (b. 1100)
 * Barthélemy de Jur, French bishop (b. 1080)
 * Oda of Brabant, Belgian prioress and saint
 * Thorbjorn Thorsteinsson, Norwegian pirate

title: 1158


text:
User:Perry Bebbington

Perry Bebbington. Living in Nottingham in the UK. Main expertise is in electronics and telecommunications, and I'll write on those subjects as and when I see something that I vaguely know anything about with a ? next to it.

Created the original entries for PDH, SDH, multiplexer, inverse multiplexer and enjoying seeing others adding to and improving my entries even after just a few days! Pity I did them before I got my username sorted out though.

More about me at http://www.bebbington.org and http://www.sepsolutions.co.uk

Feel free to leave me messages on this page.

Perry, I responded to your query on my talk page (sorry for the delay!) Verloren

title: User:Perry Bebbington


text:
Hebron

Hebron (الخليل, or خَلِيل الرَّحْمَن ; חֶבְרוֹן , ) is a Palestinian  city in the southern West Bank, 30 km south of Jerusalem. Nestled in the Judaean Mountains, it lies 930 m above sea level. The second-largest city in the West Bank (after East Jerusalem), and the third-largest in the Palestinian territories (after East Jerusalem and Gaza), it had a population of 201,063 Palestinians in 2017, and seven hundred Jewish settlers concentrated on the outskirts of its Old City. Since 1997, the city has been under the civil control of the Palestinian Authority, though the Israeli military maintains a presence in an area comprising 20% of the city known as H2. Hebron includes the Cave of the Patriarchs, which Jewish, Christian, and Islamic traditions all designate as the burial site of three key patriarchal/matriarchal couples. The city is often considered one of the four holy cities in Judaism as well as in Islam.

Hebron is considered one of the oldest cities in the Levant. According to the Bible, Abraham settled in Hebron and bought the Cave of the Patriarchs as a burial place for his wife Sarah. Biblical tradition holds that the patriarchs Abraham, Isaac, and Jacob, along with their wives Sarah, Rebecca, and Leah, were buried in the cave. Hebron is also recognized in the Bible as the place where David was anointed king of Israel. Following the Babylonian captivity, the Edomites settled in Hebron. During the first century BCE, Herod the Great built the wall that still surrounds the Cave of the Patriarchs, which later became a church, and then a mosque. With the exception of a brief Crusader control, successive Muslim dynasties ruled Hebron from the 6th century CE until the Ottoman Empire's dissolution following World War I, when the city became part of British Mandatory Palestine.

A massacre in 1929 and the Arab uprising of 1936–39 led to the emigration of the Jewish community from Hebron. The 1948 Arab–Israeli War saw the entire West Bank, including Hebron, occupied and annexed by Jordan, and since the 1967 Six-Day War, the city has been under Israeli military occupation. Following Israeli occupation, Jewish presence was reestablished at the city. Since the 1997 Hebron Protocol, most of Hebron has been governed by the Palestinian National Authority. The city is often described as a "microcosm" of the Israeli–Palestinian conflict and the Israeli occupation of the West Bank. The Hebron Protocol of 1997 divided the city into two sectors: H1, controlled by the Palestinian National Authority, and H2, roughly 20% of the city, including 35,000 Palestinians, under Israeli military administration.

All security arrangements and travel permits for local residents are coordinated between the Palestinian National Authority and Israel via the Israeli military administration of the West Bank (COGAT). The Jewish settlers have their own governing municipal body, the Committee of the Jewish Community of Hebron. Today, Hebron is the capital of the Hebron Governorate, the largest governorate of the State of Palestine, with an estimated population of around 782,227. It is a busy hub of West Bank trade, generating roughly a third of the area's gross domestic product, largely due to the sale of limestone from quarries in its area. It has a local reputation for its grapes, figs, limestone, pottery workshops, metalworking workshops and glassblowing factories. The old city of Hebron features narrow, winding streets, flat-roofed stone houses, and old bazaars. The city is home to Hebron University, Al-Quds Open University and the Palestine Polytechnic University.

Etymology
The name "Hebron" appears to trace back to two northwest Semitic languages, which coalesce in the form ḥbr, having reflexes in Hebrew and Amorite, with a basic sense of 'unite' and connoting a range of meanings from "colleague" to "friend". In the proper name Hebron, the original sense may have been alliance.

The Arabic name for Hebron, al-Khalīl, emerged as the city's actual name in the 13th century. Earlier Muslim sources refer to the city as Ḥabra or Ḥabrūn. The name al-Khalīl derives from the Qur'anic epithet for Abraham, Khalil al-Rahman (إبراهيم خليل الرحمن) "Beloved of the Merciful" or "Friend of God". Arabic Al-Khalil thus precisely translates the ancient Hebrew toponym Ḥebron, understood as ḥaḇer (friend).

Bronze and Iron Age
Archaeological excavations reveal traces of strong fortifications dated to the Early Bronze Age, covering some 24–30 dunams centered around Tel Rumeida. The city flourished in the 17th–18th centuries BCE before being destroyed by fire, and was resettled in the late Middle Bronze Age. This older Hebron was originally a Canaanite royal city. Abrahamic legend associates the city with the Hittites. It has been conjectured that Hebron might have been the capital of Shuwardata of Gath, an Indo-European contemporary of Jerusalem's regent, Abdi-Ḫeba, although the Hebron hills were almost devoid of settlements in the Late Bronze Age. The Abrahamic traditions associated with Hebron are nomadic. This may also reflect a Kenite element, since the nomadic Kenites are said to have long occupied the city, and Heber is the name for a Kenite clan. In the narrative of the later Hebrew conquest, Hebron was one of two centres under Canaanite control. They were ruled by the three sons of Anak (benê/yelîdê hāʿănaq). or may reflect some Kenite and Kenizzite migration from the Negev to Hebron, since terms related to the Kenizzites appear to be close to Hurrian. This suggests that behind the Anakim legend lies some early Hurrian population. In Biblical lore they are represented as descendants of the Nephilim. The Book of Genesis mentions that it was formerly called Kirjath-arba, or "city of four", possibly referring to the four pairs or couples who were buried there, or four tribes, or four quarters, four hills, or a confederated settlement of four families.

The story of Abraham's purchase of the Cave of the Patriarchs from the Hittites constitutes a seminal element in what was to become the Jewish attachment to the land in that it signified the first "real estate" of Israel long before the conquest under Joshua. In settling here, Abraham is described as making his first covenant, an alliance with two local Amorite clans who became his ba'alei brit or masters of the covenant. The Hebron of the Israelites was centered on what is now known as Tel Rumeida, while its ritual centre was located at Elonei Mamre. Hebrew Bible narrative also describes the city.

It is said to have been wrested from the Canaanites by either Joshua, who is said to have wiped out all of its previous inhabitants, "destroying everything that drew breath, as the Lord God of Israel had commanded", or the Tribe of Judah as a whole, or specifically Caleb the Judahite. The town itself, with some contiguous pasture land, is then said to have been granted to the Levites of the clan of Kohath, while the fields of the city, as well as its surrounding villages were assigned to Caleb, who expels the three giants, Sheshai, Ahiman, and Talmai, who ruled the city. Later, the biblical narrative has King David called by God to relocate to Hebron and reign from there for some seven years. It is there that the elders of Israel come to him to make a covenant before Elohim and anoint him king of Israel. It was in Hebron again that Absalom has himself declared king and then raises a revolt against his father David. It became one of the principal centers of the Tribe of Judah and was classified as one of the six traditional Cities of Refuge.

As is shown by the discovery at Lachish, the second most important city in the Kingdom of Judah after Jerusalem, of seals with the inscription lmlk Hebron (to the king Hebron), Hebron continued to constitute an important local economic centre, given its strategic position on the crossroads between the Dead Sea to the east, Jerusalem to the north, the Negev and Egypt to the south, and the Shepelah and the coastal plain to the west. Lying along trading routes, it remained administratively and politically dependent on Jerusalem for this period.

Classic antiquity
After the destruction of the First Temple, most of the Jewish inhabitants of Hebron were exiled, and according to the conventional view, some researchers found traces of Edomite presence after the 5th–4th centuries BCE, as the area became Achaemenid province, and, in the wake of Alexander the Great's conquest, Hebron was throughout the Hellenistic period under the influence of Idumea (as the new area inhabited by the Edomites was called during the Persian, Hellenistic and Roman periods), as is attested by inscriptions for that period bearing names with the Edomite God Qōs. Jews also appear to have lived there after the return from the Babylonian exile. During the Maccabean revolt, Hebron was burnt and plundered by Judah Maccabee who fought against the Edomites in 167 BCE. The city appears to have long resisted Hasmonean dominance, however, and indeed as late as the First Jewish–Roman War was still considered Idumean.

The present day city of Hebron was settled in the valley downhill from Tel Rumeida at the latest by Roman times. Herod the Great, king of Judea, built the wall that still surrounds the Cave of the Patriarchs. During the First Jewish–Roman War, Hebron was captured and plundered by Simon Bar Giora, a leader of the Zealots, without bloodshed. The "little town" was later laid to waste by Vespasian's officer Sextus Vettulenus Cerialis. Josephus wrote that he "slew all he found there, young and old, and burnt down the town." After the suppression of the Bar Kokhba revolt in 135 CE, innumerable Jewish captives were sold into slavery at Hebron's Terebinth slave-market.

The city was part of the Byzantine Empire in Palaestina Prima province at the Diocese of the East. The Byzantine emperor Justinian I erected a Christian church over the Cave of Machpelah in the 6th century CE, which was later destroyed by the Sassanid general Shahrbaraz in 614 when Khosrau II's armies besieged and took Jerusalem. Jews were not permitted to reside in Hebron under Byzantine rule. The sanctuary itself however was spared by the Persians, in deference to the Jewish population, who were numerous in the Sassanid army.

Muslim conquest and Islamic caliphate
Hebron was one of the last cities of Palestine to fall to the Islamic invasion in the 7th century, possibly the reason why Hebron is not mentioned in any traditions of the Arab conquest. When the Rashidun Caliphate established its rule over Hebron in 638, the Muslims converted the Byzantine church at the site of Abraham's tomb into a mosque. It became an important station on the caravan trading route from Egypt, and also as a way-station for pilgrims making the yearly hajj from Damascus. After the fall of the city, Jerusalem's conqueror, Caliph Omar ibn al-Khattab permitted Jewish people to return and to construct a small synagogue within the Herodian precinct.

Catholic bishop Arculf, who visited the Holy Land during the Umayyad period, described the city as unfortified and poor. In his writings he also mentioned camel caravans transporting firewood from Hebron to Jerusalem, which implies there was a presence of Arab nomads in the region at that time. Trade greatly expanded, in particular with Bedouins in the Negev (al-Naqab) and the population to the east of the Dead Sea (Baḥr Lūṭ). According to Anton Kisa, Jews from Hebron (and Tyre) founded the Venetian glass industry in the 9th century.

Hebron was almost absent from Muslim literature before the 10th century. In 985, al-Muqaddasi described Hebron (Habra) as the village of Abraham al-Khalil, with a strong fortress and a stone dome over Abraham's sepulchre. The mosque contained the tombs of Isaac, Jacob, and their wives. Surrounding the area were villages with vineyards producing exceptional grapes and apples. Hebron had a public guest house offering lentils and olive oil to both the poor and the rich. The guest house was established through the bequest of Prophet Muhammad's companions, including Tamim-al Dari, and received generous donations. It was highly regarded as an excellent house of hospitality and charity in the realm of al-Islam. The custom, known as the 'Table of Abraham' (simāt al-khalil), was similar to the one established by the Fatimids. In 1047, Nasir-i-Khusraw described Hebron in his Safarnama as having many villages providing revenues for pious purposes. He mentioned a spring flowing from under a stone, with water channeled to a covered tank outside the town. The Sanctuary stood on the town's southern border, enclosed by four walls. Barley was the primary crop, with abundant olives. Visitors were provided with bread, olives, lentils cooked in olive oil, and raisins. Hebron had numerous mills operated by oxen and mules, along with working girls baking bread. The hospitality extended to about three-pound loaves of bread and meals for every arriving person, including up to 500 pilgrims on certain days.

The tradition survives to this day in the form of the Takiat Ibrahim soup kitchen, which has been active in providing food for thousands over Ramadan, which coincided with food shortages during the 2024 Israel–Hamas war. Geniza documents from this period mention "the graves of the patriarchs" and attest to the presence of an organised Jewish community in Hebron. The Jews maintained a synagogue near the tomb and earned their livelihood accommodating Jewish pilgrims and merchants. During the Seljuk period, the community was headed by Saadia b. Abraham b. Nathan, known as the "haver of the graves of the patriarchs."

Crusader and Ayyubid period
The Caliphate lasted in the area until 1099, when the Christian Crusader Godfrey de Bouillon took Hebron and renamed it "Castellion Saint Abraham". It was designated capital of the southern district of the Crusader Kingdom of Jerusalem and given, in turn, as the fief of Saint Abraham, to Geldemar Carpinel, the bishop Gerard of Avesnes, Hugh of Rebecques, Walter Mohamet and Baldwin of Saint Abraham. As a Frankish garrison of the Kingdom of Jerusalem, its defence was precarious being 'little more than an island in a Moslem ocean'. The Crusaders converted the mosque and the synagogue into a church. In 1106, an Egyptian campaign thrust into southern Palestine and almost succeeded the following year in wresting Hebron back from the Crusaders under Baldwin I of Jerusalem, who personally led the counter-charge to beat the Muslim forces off. In the year 1113 during the reign of Baldwin II of Jerusalem, according to Ali of Herat (writing in 1173), a certain part over the cave of Abraham had given way, and "a number of Franks had made their entrance therein". And they discovered "(the bodies) of Abraham, Isaac and Jacob", "their shrouds having fallen to pieces, lying propped up against a wall...Then the King, after providing new shrouds, caused the place to be closed once more". Similar information is given in Ibn at Athir's Chronicle under the year 1119; "In this year was opened the tomb of Abraham, and those of his two sons Isaac and Jacob ...Many people saw the Patriarch. Their limbs had nowise been disturbed, and beside them were placed lamps of gold and of silver." The Damascene nobleman and historian Ibn al-Qalanisi in his chronicle also alludes at this time to the discovery of relics purported to be those of Abraham, Isaac and Jacob, a discovery that excited eager curiosity among all three communities in Palestine, Muslim, Jewish, and Christian. Towards the end of the period of Crusader rule, in 1166 Maimonides visited Hebron and wrote,"On Sunday, 9 Marheshvan (17 October), I left Jerusalem for Hebron to kiss the tombs of my ancestors in the Cave. On that day, I stood in the cave and prayed, praise be to God, (in gratitude) for everything."

A royal domain, Hebron was handed over to Philip of Milly in 1161 and joined with the Seigneurie of Transjordan. A bishop was appointed to Hebron in 1168 and the new cathedral church of St Abraham was built in the southern part of the Haram. In 1167, the episcopal see of Hebron was created along with that of Kerak and Sebastia (the tomb of John the Baptist). In 1170, Benjamin of Tudela visited Hebron, referred to as in its Frankish name St. Abram de Bron. He mentioned the great church called St. Abram, which was once a Jewish place of worship during the time of Muslim rule. The Gentiles had erected six tombs there, claimed to be those of Abraham, Sarah, Isaac, Rebekah, Jacob, and Leah. The custodians collected money from pilgrims by presenting these tombs as the tombs of the Patriarchs. However, if a Jew offered a special reward, they would open an iron gate leading to a series of empty caves, until reaching the third cave where the actual sepulchers of the Patriarchs and Matriarchs were said to be located.

The Kurdish Muslim Saladin retook Hebron in 1187 – again with Jewish assistance according to one late tradition, in exchange for a letter of security allowing them to return to the city and build a synagogue there. The name of the city was changed back to Al-Khalil. A Kurdish quarter still existed in the town during the early period of Ottoman rule. Richard the Lionheart retook the city soon after. Richard of Cornwall, brought from England to settle the dangerous feuding between Templars and Hospitallers, whose rivalry imperiled the treaty guaranteeing regional stability stipulated with the Egyptian Sultan As-Salih Ayyub, managed to impose peace on the area. But soon after his departure, feuding broke out and in 1241 the Templars mounted a damaging raid on what was, by now, Muslim Hebron, in violation of agreements.

In 1244, the Khwarazmians destroyed the town, but left the sanctuary untouched.

Mamluk period
In 1260, after Mamluk Sultan Baibars defeated the Mongol army, the minarets were built onto the sanctuary. Six years later, while on pilgrimage to Hebron, Baibars promulgated an edict forbidding Christians and Jews from entering the sanctuary, and the climate became less tolerant of Jews and Christians than it had been under the prior Ayyubid rule. The edict for the exclusion of Christians and Jews was not strictly enforced until the middle of the 14th-century and by 1490, not even Muslims were permitted to enter the caverns. The mill at Artas was built in 1307, and the profits from its income were dedicated to the hospital in Hebron. Between 1318 and 1320, the Na'ib of Gaza and much of coastal and interior Palestine ordered the construction of Jawli Mosque to enlarge the prayer space for worshipers at the Ibrahimi Mosque.

Hebron was visited by some important rabbis over the next two centuries, among them Nachmanides (1270) and Ishtori HaParchi (1322) who noted the old Jewish cemetery there. Sunni imam Ibn Qayyim Al-Jawziyya (1292–1350) was penalised by the religious authorities in Damascus for refusing to recognise Hebron as a Muslim pilgrimage site, a view also held by his teacher Ibn Taymiyyah. The Jewish-Italian traveller, Meshullam of Volterra (1481) found not more than twenty Jewish families living in Hebron. and recounted how the Jewish women of Hebron would disguise themselves with a veil in order to pass as Muslim women and enter the Cave of the Patriarchs without being recognized as Jews. Minute descriptions of Hebron were recorded in Stephen von Gumpenberg's Journal (1449), by Felix Fabri (1483) and by Mejr ed-Din It was in this period, also, that the Mamluk Sultan Qa'it Bay revived the old custom of the Hebron "table of Abraham", and exported it as a model for his own madrasa in Medina. This became an immense charitable establishment near the Haram, distributing daily some 1,200 loaves of bread to travellers of all faiths. The Italian rabbi Obadiah ben Abraham Bartenura wrote around 1490:"I was in the Cave of Machpelah, over which the mosque has been built; and the Arabs hold the place in high honour. All the Kings of the Arabs come here to repeat their prayers, but neither a Jew nor an Arab may enter the Cave itself, where the real graves of the Patriarchs are; the Arabs remain above, and let down burning torches into it through a window, for they keep a light always burning there. . Bread and lentil, or some other kind of pulse (seeds of peas or beans), is distributed (by the Muslims) to the poor every day without distinction of faith, and this is done in honour of Abraham."

Early Ottoman period

The expansion of the Ottoman Empire along the southern Mediterranean coast under sultan Selim I coincided with the establishment of Inquisition commissions by the Catholic Monarchs in Spain in 1478, which ended centuries of the Iberian convivencia (coexistence). The ensuing expulsions of the Jews drove many Sephardi Jews into the Ottoman provinces, and a slow influx of Jews to the Holy Land took place, with some notable Sephardi kabbalists settling in Hebron. Over the following two centuries, there was a significant migration of Bedouin tribal groups from the Arabian Peninsula into Palestine. Many settled in three separate villages in the Wādī al-Khalīl, and their descendants later formed the majority of Hebron.

The Jewish community fluctuated between 8–10 families throughout the 16th century, and suffered from severe financial straits in the first half of the century. In 1540, renowned kabbalist Malkiel Ashkenazi bought a courtyard from the small Karaite community, in which he established the Sephardic Abraham Avinu Synagogue. In 1659, Abraham Pereyra of Amsterdam founded the Hesed Le'Abraham yeshiva in Hebron, which attracted many students. In the early 18th century, the Jewish community suffered from heavy debts, almost quadrupling from 1717 to 1729, and were "almost crushed" from the extortion practiced by the Turkish pashas. In 1773 or 1775, a substantial amount of money was extorted from the Jewish community, who paid up to avert a threatened catastrophe, after a false allegation was made accusing them of having murdered the son of a local sheikh and throwing his body into a cesspit.> Emissaries from the community were frequently sent overseas to solicit funds. During the Ottoman period, the dilapidated state of the patriarchs' tombs was restored to a semblance of sumptuous dignity. Ali Bey who, under Muslim disguise, was one of the few Westerners to gain access, reported in 1807 that, "all the sepulchres of the patriarchs are covered with rich carpets of green silk, magnificently embroidered with gold; those of the wives are red, embroidered in like manner. The sultans of Constantinople furnish these carpets, which are renewed from time to time. Ali Bey counted nine, one over the other, upon the sepulchre of Abraham." Hebron also became known throughout the Arab world for its glass production, abetted by Bedouin trade networks that brought up minerals from the Dead Sea, and the industry is mentioned in the books of 19th century Western travellers to Palestine. For example, Ulrich Jasper Seetzen noted during his travels in Palestine in 1808–09 that 150 persons were employed in the glass industry in Hebron, based on 26 kilns. In 1833, a report on the town appearing in a weekly paper printed by the London-based Religious Tract Society wrote that Hebron's population had 400 Arab families, had numerous well-provisioned shops and that there was a manufactory of glass lamps, which were exported to Egypt. Early 19th-century travellers also noticed Hebron's flourishing agriculture. Apart from glassware, it was a major exporter of dibse, grape sugar, from the famous Dabookeh grapestock characteristic of Hebron.

An Arab peasants' revolt broke out in April 1834 when Ibrahim Pasha of Egypt announced he would recruit troops from the local Muslim population. Hebron, headed by its nazir Abd ar-Rahman Amr, declined to supply its quota of conscripts for the army and suffered badly from the Egyptian campaign to crush the uprising. The town was invested and, when its defences fell on August 4, it was sacked by Ibrahim Pasha's army. An estimated 500 Muslims from Hebron were killed in the attack and some 750 were conscripted. 120 youths were abducted and put at the disposal of Egyptian army officers. Most of the Muslim population managed to flee beforehand to the hills. Many Jews fled to Jerusalem, but during the general pillage of the town at least five were killed. In 1838, the total population was estimated at 10,000. When the government of Ibrahim Pasha fell in 1841, the local clan leader Abd ar-Rahman Amr once again resumed the reins of power as the Sheik of Hebron. Due to his extortionate demands for cash from the local population, most of the Jewish population fled to Jerusalem. In 1846, the Ottoman Governor-in-chief of Jerusalem (serasker), Kıbrıslı Mehmed Emin Pasha, waged a campaign to subdue rebellious sheiks in the Hebron area, and while doing so, allowed his troops to sack the town. Though it was widely rumoured that he secretly protected Abd ar-Rahman, the latter was deported together with other local leaders (such as Muslih al-'Azza of Bayt Jibrin), but he managed to return to the area in 1848.

According to Hillel Cohen, the attacks on Jews in this particular period are an exception that proves the rule, that one of the easiest place for Jews to live in the world were in the various countries of the Ottoman Empire. In the mid-eighteenth century, rabbi Abraham Gershon of Kitov wrote from Hebron that:"the gentiles here very much love the Jews. When there is a brit milah (circumcision ceremony) or any other celebration, their most important men come at night and rejoice with the Jews and clap hands and dance with the Jews, just like the Jews'."

Late Ottoman period

By 1850, the Jewish population consisted of 45–60 Sephardic families, some 40 born in the town, and a 30-year-old Ashkenazic community of 50 families, mainly Polish and Russian, the Lubavitch Hasidic movement having established a community in 1823. The ascendency of Ibrahim Pasha led to a decline in the local glass industry. His plan to build a Mediterranean fleet led to severe logging in Hebron's forests, making firewood for the kilns scarce. At the same time, Egypt began importing cheap European glass. The rerouting of the hajj from Damascus through Transjordan reduced traffic to Hebron, and the Suez Canal (1869) precipitated a drop in caravan trade. The consequence was a steady deterioration of the local economy. At the time, the town was divided into four quarters: the Ancient Quarter (Harat al-Kadim) near the Cave of Machpelah; to its south, the Quarter of the Silk Merchant (Harat al-Kazaz), inhabited by Jews; the Mamluk-era Sheikh's Quarter (Harat ash Sheikh) to the north-west; and further north, the Dense Quarter (Harat al-Harbah). In 1855, the newly appointed Ottoman pasha ("governor") of the sanjak ("district") of Jerusalem, Kamil Pasha, attempted to put down a rebellion in the Hebron region. Kamil and his army marched towards Hebron in July 1855, a scene witnessed by representatives of the English, French and other Western consulates. After crushing all opposition, Kamil appointed Salama Amr, brother and rival of Abd al Rachman, as nazir of the Hebron region. Relative quiet reigned in the town for the next 4 years. In 1866, Hungarian Jews of the Karlin Hasidic court settled in Hebron. According to Nadav Shragai, Arab-Jewish relations were good, and Alter Rivlin, who spoke Arabic and Syrian-Aramaic, was appointed Jewish representative to the city council. During a severe drought in 1869–1871,  food in Hebron sold for ten times the normal amount. From 1874, the Hebron district was administered directly from Istanbul as part of the Sanjak of Jerusalem. By 1874, when C.R. Conder visited Hebron under the auspices of the Palestine Exploration Fund, the Jewish community numbered  600 in an overall population of 17,000. The Jews lived in the Quarter of the Corner Gate. In the late 19th century the production of Hebron glass declined due to competition from imported European glassware, although it continued to be popular among those who could not afford luxury goods and was sold by Jewish merchants. Glass ornaments from Hebron were exhibited at the World Fair of 1873 in Vienna.

A report from the French consul in 1886 suggests that glass-making remained an important source of income for Hebron, with four factories earning 60,000 francs yearly. While the economy of other cities in Palestine was based on solely on trade, the economy of Hebron was more diverse, including agriculture and livestock herding, alone with glassware manufacturing and processing of hides. This was because the most fertile lands were situated within the city limits. Even so, Hebron had an image of being unproductive and  an "asylum for the poor and the spiritual." While the wealthy merchants of Nablus built fine mansions, housing in Hebron consisted of semi-peasant dwellings.

Hebron was described as 'deeply Bedouin and Islamic', and 'bleakly conservative' in its religious outlook, with a strong tradition of hostility to Jews. It had a reputation for religious zeal in jealously protecting its sites from Jews and Christians, although the Jewish and Christian communities seem to have been an integral part of  the local economy. As income from commerce declined and tax revenues diminished significantly, the Ottoman government left Hebron to manage its own affairs for the most part, making it "one of the most autonomous regions in late Ottoman Palestine." The Jewish community was under French protection until 1914. The Jewish presence itself was divided between the traditional Sephardi community, whose members spoke Arabic and adopted Arab dress, and the more recent influx of Ashkenazi Jews. They prayed in different synagogues, sent their children to different schools, lived in different quarters and did not intermarry. The community was largely Orthodox and anti-Zionist.

British Mandate

The British occupied Hebron on December 8, 1917; governance transited to a mandate in 1920. Most of Hebron was owned by old Islamic charitable endowments (waqfs), with about 60% of all the land in and around Hebron belonging to the Tamīm al-Dārī waqf. In 1922, its population stood at 16,577, of which 16,074 (97%) were Muslim, 430 (2.5%) were Jewish and 73 (0.4%) were Christian. During the 1920s, Abd al-Ḥayy al-Khaṭīb was appointed Mufti of Hebron. Before his appointment, he had been a staunch opponent of Haj Amin, supported the Muslim National Associations and had good contacts with the Zionists. Later, al-Khaṭīb became one of the few loyal followers of Haj Amin in Hebron. During the late Ottoman period, a new ruling elite had emerged in Palestine. They later formed the core of the growing Arab nationalist movement in the early 20th century. During the Mandate period, delegates from Hebron constituted only 1 per cent of the political leadership. The Palestinian Arab decision to boycott the 1923 elections for a Legislative Council was made at the fifth Palestinian Congress, after it was reported by Murshid Shahin (an Arab pro-Zionist activist) that there was intense resistance in Hebron to the elections. Almost no house in Hebron remained undamaged when an earthquake struck Palestine on July 11, 1927.

The Cave of the Patriarchs continued to remain officially closed to non-Muslims, and reports that entry to the site had been relaxed in 1928 were denied by the Supreme Muslim Council.

At this time following attempts by the Lithuanian government to draft yeshiva students into the army, the Lithuanian Hebron Yeshiva (Knesses Yisroel) relocated to Hebron, after consultations between Rabbi Nosson Tzvi Finkel, Yechezkel Sarna and Moshe Mordechai Epstein. and by 1929 had attracted some 265 students from Europe and the United States. The majority of the Jewish population lived on the outskirts of Hebron along the roads to Be'ersheba and Jerusalem, renting homes owned by Arabs, a number of which were built for the express purpose of housing Jewish tenants, with a few dozen within the city around the synagogues. During the 1929 Hebron massacre, Arab rioters slaughtered some 64 to 67 Jewish men, women and children and wounded 60, and Jewish homes and synagogues were ransacked; 435 Jews survived by virtue of the shelter and assistance offered them by their Arab neighbours, who hid them. Some Hebron Arabs, including Ahmad Rashid al-Hirbawi, president of Hebron chamber of commerce, supported the return of Jews after the massacre. Two years later, 35 families moved back into the ruins of the Jewish quarter, but on the eve of the Palestinian Arab revolt (April 23, 1936) the British Government decided to move the Jewish community out of Hebron as a precautionary measure to secure its safety. The sole exception was the 8th generation Hebronite Ya'akov ben Shalom Ezra, who processed dairy products in the city, blended in well with its social landscape and resided there under the protection of friends. In November 1947, in anticipation of the UN partition vote, the Ezra family closed its shop and left the city. Yossi Ezra has since tried to regain his family's property through the Israeli courts.

Jordanian period
At the beginning of the 1948 Arab–Israeli War, Egypt took control of Hebron. Between May and October, Egypt and Jordan tussled for dominance in Hebron and its environs. Both countries appointed military governors in the town, hoping to gain recognition from Hebron officials. The Egyptians managed to persuade the pro-Jordanian mayor to support their rule, at least superficially, but local opinion turned against them when they imposed taxes. Villagers surrounding Hebron resisted and skirmishes broke out in which some were killed. By late 1948, part of the Egyptian forces from Bethlehem to Hebron had been cut off from their lines of supply and Glubb Pasha sent 350 Arab Legionnaires and an armoured car unit to Hebron to reinforce them there. When the Armistice was signed, the city thus fell under Jordanian military control. The armistice agreement between Israel with Jordan intended to allow Israeli Jewish pilgrims to visit Hebron, but, as Jews of all nationalities were forbidden by Jordan into the country, this did not occur.

In December 1948, the Jericho Conference, held by Jordan, was convened to decide the future of the West Bank. Hebron notables, headed by mayor Muhamad 'Ali al-Ja'bari, voted in favour of becoming part of Jordan and to recognise Abdullah I of Jordan as their king. The subsequent unilateral annexation benefited the Arabs of Hebron, who during the 1950s, played a significant role in the economic development of Jordan.

Although a significant number of people relocated to Jerusalem from Hebron during the Jordanian period, Hebron itself saw a considerable increase in population with 35,000 settling in the town. During this period, signs of the previous Jewish presence in Hebron were removed.

Israeli occupation

After the Six-Day War in June 1967, Israel occupied Hebron along with the rest of the West Bank, establishing a military government to rule the area. In an attempt to reach a land for peace deal, Yigal Allon proposed that Israel annex 45% of the West Bank and return the remainder to Jordan. According to the Allon Plan, the city of Hebron would lie in Jordanian territory, and in order to determine Israel's own border, Allon suggested building a Jewish settlement adjacent to Hebron. David Ben-Gurion also considered that Hebron was the one sector of the conquered territories that should remain under Jewish control and be open to Jewish settlement. Apart from its symbolic message to the international community that Israel's rights in Hebron were, according to Jews, inalienable, settling Hebron also had theological significance in some quarters. For some, the capture of Hebron by Israel had unleashed a messianic fervor.

Survivors and descendants of the prior community are mixed. Some support the project of Jewish redevelopment, others commend living in peace with Hebronite Arabs, while a third group recommend a full pullout. Descendants supporting the latter views have met with Palestinian leaders in Hebron. In 1997 one group of descendants dissociated themselves from the settlers by calling them an obstacle to peace. On May 15, 2006, a member of a group who is a direct descendant of the 1929 refugees urged the government to continue its support of Jewish settlement, and allow the return of eight families evacuated the previous January from homes they set up in emptied shops near the Avraham Avinu neighborhood. Beit HaShalom, established in 2007 under disputed circumstances, was under court orders permitting its forced evacuation. All the Jewish settlers were expelled on December 3, 2008.

Immediately after the 1967 war, mayor al-Ja'bari had unsuccessfully promoted the creation of an autonomous Palestinian entity in the West Bank, and by 1972, he was advocating for a confederal arrangement with Jordan instead. al-Ja'bari nevertheless consistently fostered a conciliatory policy towards Israel. He was ousted by Fahad Qawasimi in the 1976 mayoral election, which marked a shift in support towards pro-PLO nationalist leaders. Supporters of Jewish settlement within Hebron see their program as the reclamation of an important heritage dating back to Biblical times, which was dispersed or, it is argued, stolen by Arabs after the massacre of 1929. The purpose of settlement is to return to the 'land of our forefathers', and the Hebron model of reclaiming sacred sites in Palestinian territories has pioneered a pattern for settlers in Bethlehem and Nablus. Many reports, foreign and Israeli, are sharply critical of the behaviour of Hebronite settlers.

Sheik Farid Khader heads the Ja'bari tribe, consisting of some 35,000 people, which is considered one of the most important tribes in Hebron. For years, members of the Ja'bari tribe were the mayors of Hebron. Khader regularly meets with settlers and Israeli government officials and is a strong opponent of both the concept of Palestinian State and the Palestinian Authority itself. Khader believes that Jews and Arabs must learn to coexist. A violent episode occurred May 2, 1980, when an Al Fatah squad killed five yeshiva students and one other person on their way home from Sabbath prayer at the Tomb of the Patriarchs. The event provided a major motivation for settlers near Hebron to join the Jewish Underground.

In the 1980s Hebron, became the center of the Jewish Kach movement, a designated terrorist organization, whose first operations started there, and provided a model for similar behaviour in other settlements. On July 26, 1983, Israeli settlers attacked the Islamic University and shot three people dead and injured over thirty others. The 1994 Shamgar Commission of Inquiry concluded that Israeli authorities had consistently failed to investigate or prosecute crimes committed by settlers against Palestinians. Hebron IDF commander Noam Tivon said that his foremost concern is to "ensure the security of the Jewish settlers" and that Israeli "soldiers have acted with the utmost restraint and have not initiated any shooting attacks or violence."

Division of Hebron
Hebron was the one city excluded from the interim agreement of September 1995 to restore rule over all Palestinian West Bank cities to the Palestinian Authority. IDF soldiers see their job as being to protect Israeli settlers from Palestinian residents, not to police the Israeli settlers. IDF soldiers are instructed to leave violent Israeli settlers for the police to deal with. Since The Oslo Agreement, violent episodes have been recurrent in the city. The Cave of the Patriarchs massacre took place on February 25, 1994, when Baruch Goldstein, an Israeli physician and resident of Kiryat Arba, opened fire on Muslims at prayer in the Ibrahimi Mosque, killing 29, and wounding 125 before the survivors overcame and killed him. Standing orders for Israeli soldiers on duty in Hebron disallowed them from firing on fellow Jews, even if they were shooting Arabs. This event was condemned by the Israeli Government, and the extreme right-wing Kach party was banned as a result. The Israeli government also tightened restrictions on the movement of Palestinians in H2, closed their vegetable and meat markets, and banned Palestinian cars on Al-Shuhada Street. The park near the Cave of the Patriarchs for recreation and barbecues is off-limits for Arab Hebronites. Following the 1995 Oslo Agreement and subsequent 1997 Hebron Agreement, Palestinian cities were placed under the exclusive jurisdiction of the Palestinian Authority, with the exception of Hebron, which was split into two sectors: H1 is controlled by the Palestinian Authority and H2 – which includes the Old City of Hebron – remained under the military control of Israel. Around 120,000 Palestinians live in H1, while around 30,000 Palestinians along with around 700 Israelis remain under Israeli military control in H2. , a total of 86 Jewish families lived in Hebron. The IDF (Israel Defense Forces) may not enter H1 unless under Palestinian escort. Palestinians cannot approach areas where settlers live without special permits from the IDF. The Jewish settlement is widely considered to be illegal by the international community, although the Israeli government disputes this. Over the period of the First Intifada and Second Intifada, the Jewish community was subjected to attacks by Palestinian militants, especially during the periods of the intifadas; which saw 3 fatal stabbings and 9 fatal shootings in between the first and second Intifada (0.9% of all fatalities in Israel and the West Bank) and 17 fatal shootings (9 soldiers and 8 settlers) and 2 fatalities from a bombing during the second Intifada, and thousands of rounds fired on it from the hills above the Abu-Sneina and Harat al-Sheikh neighbourhoods. On November 15, 2002, 12 Israeli soldiers were killed (Hebron Brigade commander Colonel Dror Weinberg and two other officers, 6 soldiers and 3 members of the security unit of Kiryat Arba) in an ambush. Two Temporary International Presence in Hebron observers were killed by Palestinian gunmen in a shooting attack on the road to Hebron  On March 27, 2001, a Palestinian sniper targeted and killed the Jewish baby Shalhevet Pass. The sniper was caught in 2002. Hebron is one of the three West Bank towns from which the majority of suicide bombers originate. In May 2003, three students of the Hebron Polytechnic University carried out three separate suicide attacks. In August 2003, in what both Islamic groups described as a retaliation, a 29-year-old preacher from Hebron, Raed Abdel-Hamed Mesk, broke a unilateral Palestinian ceasefire by killing 23 and injured over 130 in a bus bombing in Jerusalem. In 2007, the Palestinian population in H2 declined due to Israeli security measures such as extended curfews, strict restrictions on movement, the closure of Palestinian businesses and settler harassment. Palestinians are barred from using Al-Shuhada Street, a principal commercial thoroughfare that is locally nicknamed "Apartheid Street" as a result.

Israeli organization B'Tselem states that there have been "grave violations" of Palestinian human rights in Hebron because of the "presence of the settlers within the city." The organization cites regular incidents of "almost daily physical violence and property damage by settlers in the city", curfews and restrictions of movement that are "among the harshest in the Occupied Territories", and violence by Israeli border policemen and the IDF against Palestinians who live in the city's H2 sector. According to Human Rights Watch, Palestinian areas of Hebron are frequently subject to indiscriminate firing by the IDF, leading to many casualties. One former IDF soldier, with experience in policing Hebron, has testified to Breaking the Silence, that on the briefing wall of his unit a sign describing their mission aim was hung that read: "To disrupt the routine of the inhabitants of the neighbourhood." Hebron mayor Mustafa Abdel Nabi invited the Christian Peacemaker Teams to assist the local Palestinian community in opposition to what they describe as Israeli military occupation, collective punishment, settler harassment, home demolitions and land expropriation. In 2017, Temporary International Presence in Hebron (TIPH) issued a confidential report covering their 20 years of work in Hebron. The report, based in part on over 40,000 incidents reported during this period, stated that Israel violated international law in Hebron and has breached the rights of residents as established by the International Covenant on Civil and Political Rights. The report claimed that Israel violated Article 49 of the Fourth Geneva Convention, which prohibits the deportation of civilians from occupied territory. Israeli settlement in Hebron was also cited as a violation.

Demographics
In 1820, it was reported that there were about 1,000 Jews in Hebron. In 1838, Hebron had an estimated 1,500 taxable Muslim households, in addition to 41 Jewish tax-payers. Taxpayers consisted here of male heads of households who owned even a very small shop or piece of land. 200 Jews and one Christian household were under 'European protections'. The total population was estimated at 10,000. In 1842, it was estimated that about 400 Arab and 120 Jewish families lived in Hebron, the latter having been diminished in number following the destruction of 1834.

Urban development
Historically, the city consisted of four densely populated quarters: the suq and Harat al-Masharqa adjacent to the Ibrahimi Mosque, the Silk Merchant Quarter (Haret Kheitun) to the south and the Sheikh Quarter (Haret al-Sheikh) to the north. It is believed the basic urban structure of the city had been established by the Mamluk period, during which time the city also had Jewish, Christian and Kurdish quarters. In the mid 19th-century, Hebron was still divided into four quarters, but the Christian quarter had disappeared. The sections included the ancient quarter surrounding the Cave of Machpelah, the Haret Kheitun (the Jewish Quarter, Haret el-Yahud), the Haret el-Sheikh and the Druze Quarter. As Hebron's population gradually increased, inhabitants preferred to build upwards rather than leave the safety of their neighbourhoods. By the 1880s, better security provided by the Ottoman authorities allowed the town to expand and a new commercial centre, Bab el-Zawiye, emerged. As development continued, new spacious and taller structures were built to the north-west. In 1918, the town consisted of dense clusters of residential dwellings along the valley, rising onto the slopes above it. By the 1920s, the town was made up of seven quarters: el-Sheikh and Bab el-Zawiye to the west, el-Kazzazin, el-Akkabi and el-Haram in the centre, el-Musharika to the south and el-Kheitun in the east. Urban sprawl had spread onto the surrounding hills by 1945. The large population increase under Jordanian rule resulted in about 1,800 new houses being built, most of them along the Hebron-Jerusalem highway, stretching northwards for over 3 mi at a depth of 600 ft (200m) either way. Some 500 houses were built elsewhere on surrounding rural land. There was less development to the south-east, where housing units extended along the valley for about 1 mile (1.5 km). In 1971, with the assistance of the Israeli and Jordanian governments, the Hebron University, an Islamic university, was founded. In an attempt to enhance the view of the Ibrahami Mosque, Jordan demolished whole blocks of ancient houses opposite its entrance, which also resulted in improved access to the historic site. The Jordanians also demolished the old synagogue located in the el-Kazzazin Quarter. In 1976, Israel recovered the site, which had been converted into an animal pen, and by 1989, a settler courtyard had been established there.

Today, the area along the north–south axis to the east comprises the modern town of Hebron (also called Upper Hebron, Khalil Foq). It was established towards the end of the Ottoman period, its inhabitants being upper and middle class Hebronites who moved there from the crowded old city, Balde al-Qadime (also called Lower Hebron, Khalil Takht). The northern part of Upper Hebron includes some up-scale residential districts and also houses the Hebron University, private hospitals and the only two luxury hotels in the city. The main commercial artery of the city is located here, situated along the Jerusalem Road, and includes modern multi-storey shopping malls. Also in this area are villas and apartment complexes built on the krum, rural lands and vineyards, which used to function as recreation areas during the summer months until the early Jordanian period. The southern part is where the working-class neighbourhoods are located, along with large industrial zones and the Hebron Polytechnic University. The main municipal and governmental buildings are located in the centre of the city. This area includes high-rise concrete and glass developments and also some distinct Ottoman era one-storey family houses, adorned with arched entrances, decorative motifs and ironwork. Hebron's domestic appliance and textile markets are located here along two parallel roads that lead to the entrance of the old city. Many of these have been relocated from the old commercial centre of the city, known as the vegetable market (hesbe), which was closed down by the Israeli military during the 1990s. The vegetable market is now located in the square of Bab el-Zawiye.

Economy
Hebron is a leading commercial and industrial center in the Levantine region. The presence of minerals and resources in surroundings have increased the city's value. It emerged as in important trade hub in the West Bank. Hebron is most productive region in the country after Jerusalem–Bethlehem–Ramallah area. The H1 Area, which is under control of Palestinian Authority have been a large contributor to the city's economy. Despite having tense relations, Israelis and Palestinians have strong trade relations in Hebron. The city is popular for its ceramics and glass industry.

From the 1970s to the early 1990s, a third of those who lived in the city worked in the shoe industry. According to the shoe factory owner Tareq Abu Felat, the number reached least 35,000 people and there were more than 1,000 workshops around the city. Statistics from the Chamber of Commerce in Hebron put the figure at 40,000 people employed in 1,200 shoe businesses. However, the 1993 Oslo Accords and 1994 Protocol on Economic Relations between Israel and the Palestine Liberation Organization (PLO) made it possible to mass import Chinese goods as the Palestinian National Authority, which was created after the Oslo Accords, did not regulate it. They later put import taxes but the Abu Felat, who also is the Palestinian Federation of Leather Industries's chairman, said more is still needed. The Palestinian government decided to impose an additional tax of 35% on products from China from April 2013.

90% of the shoes in Palestine are now estimated to come from China, which Palestinian industry workers say are of much lower quality but also much cheaper, and the Chinese are more aesthetic. Another factor contributing to the decline of the local industry is Israeli restrictions on Palestinian exports. Today, there are less than 300 workshops in the shoe industry, who only run part-time, and they employ around 3,000–4,000 people. More than 50% of the shoes are exported to Israel, where consumers have a better economy. Less than 25% goes to the Palestinian market, with some going to Jordan, Saudi Arabia and other Arab countries.

Hebron is major source of import goods to Israel. Mattresses manufactured in Hebron are exported to Israeli markets in Tel Aviv, Beersheba and Haifa. Around 17,000 factories and workshops are located throughout the Area H1. Historically, the traditional glass industry is popular in Hebron. A new industrial city has been built in Tarqumiyah, which houses more than 140 factories. Royal Industrial Trading operates a pipe manufacturing plant in Hebron, which is spread across an area of 40000 m2 and employs over 650 people. In 2021, an electronic recycling factory was opened in Idhna and operates to this day. The European Union and the World Bank proposed to construct a regional water treatment plant, which will treat existing sewage stream coming from 80% of the city. The city is a hub for the jewelry industry and houses approximately 70 jewelry factories employing over 1500 workers.

Super Nimer company manufactures sanitary ware products and water network from its factory, whose area ranges from 30000 m2 to 45000 m2. Opened in 2004, Super Tiger operates a factory spread across an area of 7 acre. During the COVID-19 pandemic in the State of Palestine, Hebron rapidly transformed into a medical supplies manufacturing hub, with numerous factories installing and commissioning new production lines for the product and was approved by the Ministry of Economy.

Political status
Under the United Nations Partition Plan for Palestine passed by the UN in 1947, Hebron was envisaged to become part of an Arab state. While the Jewish leaders accepted the partition plan, the Arab leadership (the Arab Higher Committee in Palestine and the Arab League) rejected it, opposing any partition. The aftermath of the 1948 war saw the city occupied and later unilaterally annexed by the kingdom of Jordan in a move supported by local Hebron officials. Following the Six-Day War of 1967, Israel occupied Hebron. In 1997, in accordance with the Hebron Agreement, Israel withdrew from 80 per cent of Hebron, which was handed over to the Palestinian Authority. Palestinian police would assume responsibilities in Area H1 and Israel would retain control in Area H2.

An international unarmed observer force—the Temporary International Presence in Hebron (TIPH) was subsequently established to help the normalization of the situation and to maintain a buffer between the Palestinian Arab population of the city and the Jewish population residing in their enclave in the old city. The TIPH operates with the permission of the Israeli government, meeting regularly with the Israeli army and the Israeli Civil Administration, and is granted free access throughout the city. In 2018, the TIPH came under criticism in Israel due to incidents where an employee was, according to the Israeli police, filmed puncturing the tires of the car of an Israeli settler, and another instance where an observer was deported after slapped a settler boy.

The post-1967 settlement in Hebron was driven by theological doctrines from the Mercaz HaRav Kook, which consider the Land of Israel and its people as holy, and believe that the messianic Age of Redemption has arrived. Hebron holds special significance in this narrative, with traditions linking it to Abraham, King David, and the entrance to the Garden of Eden. Settling in Hebron is seen as a right and duty, a favor to the world, and an example of being "a light unto the nations." and an example of the Jews of Hebron being "a light unto the nations" (Or la-Goyim) However, this viewpoint has led to religiously motivated violence towards Palestinians, who are viewed negatively. Clashes with Palestinians are seen as contributing to the messianic process, with the belief that Arabs will eventually have to leave. The new settlers have no kin connection to the traditional Old Families of Jewish Hebronites, who strongly oppose their presence.

Occupation and settlements
In 1968, Rabbi Moshe Levinger and a group of Israelis, disguised as tourists, rented the main hotel in Hebron and refused to leave. The government initially wanted to evacuate the settlers but eventually allowed them to relocate to a nearby military base, which became the settlement of Kiryat Arba. After lobbying efforts, the settlement gained support from some Israeli leaders. Over time, the settlement expanded with the outpost Givat Ha'avot. The operation was planned and financed by the Movement for Greater Israel. In 2011, the Israeli Supreme Court ruled that Jews have no right to properties they possessed in places like Hebron before 1948 and are not entitled to compensation for their losses. Originally named Hesed l'Avraham clinic, Beit Hadassah was constructed in 1893 with donations of Baghdadi Jews families and was the only modern medical facility in Hebron. In 1909, it was renamed after Hadassah Women's Zionist Organization of America, which took responsibility for the medical staff and provided free medical care to all. In 1979, a group of 15 settler mothers and their 35 children squatted in the Dabouia building in Hebron, exploiting the government's indecision during negotiations with Egypt. Led by Miriam Levinger, they established a bridgehead for Jewish resettlement and created conflict with Arab shopkeepers. A retaliatory attack by a Palestinian group resulted in the death of six yeshiva students. Despite appeals to the Israeli Supreme Court, the settlers remained. The following year, the government legitimized residency in Hebron and expelled the elected mayor. This pattern of settlement followed by hostilities with Palestinians was repeated in Tel Rumeida. The Abraham Avinu Synagogue was the physical and spiritual center of its neighborhood and regarded as one of the most beautiful synagogues in Palestine. It was the centre of Jewish worship in Hebron until it was burnt down during the 1929 riots. In 1948 under Jordanian rule, the remaining ruins were razed. The Avraham Avinu quarter was established next to the Vegetable and Wholesale Markets on Al-Shuhada Street in the south of the Old City. The vegetable market was closed by the Israeli military and some of the neighbouring houses were occupied by settlers and soldiers. Settlers started to take over the closed Palestinian stores, despite explicit orders of the Israeli Supreme Court that the settlers should vacate these stores and the Palestinians should be allowed to return. Beit Romano was built and owned by Yisrael Avraham Romano of Constantinople and served Sephardi Jews from Turkey. In 1901, a Yeshiva was established there with a dozen teachers and up to 60 students. In 1982, Israeli authorities took over a Palestinian education office (Osama Ben Munqez School) and the adjacent bus station. The school was turned into a settlement, and the bus station into a military base against an order of the Israeli Supreme Court. In 1807 the immigrant Sephardic Rabbi Haim Yeshua Hamitzri (Haim the Jewish Egyptian) purchased 5 dunams on the outskirts of the city and in 1811 he signed a contract for a 99-year lease on a further 800 dunams of land, which included 4 plots in Tel Rumeida. The plots were administered by his descendant Haim Bajaio after Jews left Hebron. Settlers' claims to this land are based on these precedents, but are dismissed by the rabbi's heir. In 1984, settlers established a caravan outpost there called (Ramat Yeshai). In 1998, the Government recognized it as a settlement, and in 2001 the Defence Minister approved the building of the first housing units.

In 2012, Israel Defense Forces called for the immediate removal of a new settlement, because it was seen as a provocation. The IDF, in accordance with settler demands, requested the removal of a Palestinian flag on a Hebronite rooftop contiguous to settlements, though no rule forbids the practice. According to Palestinians, the IDF negotiated the removal of the flag in exchange for the release of a resident of Hebron from legal custody. In August 2016, Israel announced its intention to allow settlement building in the military compound of Plugat Hamitkanim in Hebron, which had been expropriated for military purposes in the 1990s. In late 2019, the Israeli Defense Minister Naftali Bennett instructed the military administration to inform the Palestinian municipality of the government's intention to reconstruct infrastructure in the old Hebron fruit and vegetable market in order to establish a Jewish neighbourhood there, which would allow for doubling the city's settler population. The area's original residents, who have protected tenancy rights there, were compelled to evacuate the zone after the Cave of the Patriarchs massacre. The original site was under Jewish ownership prior to 1948. The plan proposes that the empty shops remain Palestinian while the units built over them house Jewish Israelis.

Historic sites
The Old City of Hebron was a declared a World Heritage Site by UNESCO on July 7, 2017, despite opposition from Israeli officials who objected to it not being called Israeli or Jewish.

The most famous historic site in Hebron is the Cave of the Patriarchs. The Herodian era structure is said to enclose the tombs of the biblical Patriarchs and Matriarchs. The Isaac Hall now serves as the Ibrahimi mosque, while the Abraham and Jacob Hall serve as a synagogue. The tombs of other biblical figures (Abner ben Ner, Otniel ben Kenaz, Ruth and Jesse) are also located in the city.

The Oak of Sibta (Oak of Abraham) is an ancient tree which, in non-Jewish tradition, is said to mark the place where Abraham pitched his tent. The Russian Orthodox Church owns the site and the nearby Abraham's Oak Holy Trinity Monastery, consecrated in 1925.

Hebron is one of the few cities to have preserved its Mamluk architecture. Many structures were built during the period, especially Sufi zawiyas. Mosques from the era include the Sheikh Ali al-Bakka and Al-Jawali mosque. The early Ottoman Abraham Avinu Synagogue in the city's historic Jewish quarter was built in 1540 and restored in 1738.

Religious traditions
Some Jewish traditions regarding Adam place him in Hebron after his expulsion from Eden. Another has Cain kill Abel there. A third has Adam and Eve buried in the cave of Machpelah. A Jewish-Christian tradition had it that Adam was formed from the red clay of the field of Damascus, near Hebron. A tradition arose in medieval Jewish texts that the Cave of the Patriarchs itself was the very entrance to the Garden of Eden. During the Middle Ages, pilgrims and the inhabitants of Hebron would eat the red earth as a charm against misfortune. Others report that the soil was harvested for export as a precious medicinal spice in Egypt, Arabia, Ethiopia and India and that the earth refilled after every digging. Legend also tells that Noah planted his vineyard on Mount Hebron. In medieval Christian tradition, Hebron was one of the three cities where Elizabeth was said to live, the legend implying that it might have been the birthplace of John the Baptist.

One Islamic tradition has it that Muhammad alighted in Hebron during his night journey from Mecca to Jerusalem, and the mosque in the city is said to conserve one of his shoes. Another tradition states that Muhammad arranged for Hebron and its surrounding villages to become part of Tamim al-Dari's domain; this was implemented during Umar's reign as caliph. According to the arrangement, al-Dari and his descendants were only permitted to tax the residents for their land and the waqf of the Ibrahimi Mosque was entrusted to them. The simat al-Khalil or "Table of Abraham" is attested to in the writings of the 11th century Persian traveller Nasir-i Khusraw. According to the account, this early Islamic food distribution center — which predates the Ottoman imarets — gave all visitors to Hebron a loaf of bread, a bowl of lentils in olive oil, and some raisins.

According to Tamara Neuman, settlement by a community of Jewish religious fundamentalists has brought about three major changes by redesigning a Palestinian area in terms of biblical imagery and origins: remaking over these revamped religious sites to endow them with an innovative centrality to Jewish worship, that, she argues, effectively erases the diasporic thrust of Jewish tradition; and writing out the overlapping aspects of Judaism, Christianity and Islam in such a way that the possibility of accommodation between the three intertwined traditions is eradicated, while the presence of Palestinians themselves is erased by violent methods.

Twin towns / sister cities
Hebron is twinned with:

 * Amman, (Jordan)
 * Beyoğlu, (Turkey)
 * Bursa,  (Turkey)
 * Casablanca, Morocco
 * Derby, England
 * Fez, (Morocco)
 * Jajmau (India)
 * Keçiören, (Turkey)
 * Kraljevo, Serbia
 * Medina, (Saudi Arabia)
 * Saint-Pierre-des-Corps, (France)
 * Şanlıurfa, (Turkey)
 * Yiwu, (China)

title: Hebron