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Aug 11

MEFLUT: Unsupervised 1D Lookup Tables for Multi-exposure Image Fusion

In this paper, we introduce a new approach for high-quality multi-exposure image fusion (MEF). We show that the fusion weights of an exposure can be encoded into a 1D lookup table (LUT), which takes pixel intensity value as input and produces fusion weight as output. We learn one 1D LUT for each exposure, then all the pixels from different exposures can query 1D LUT of that exposure independently for high-quality and efficient fusion. Specifically, to learn these 1D LUTs, we involve attention mechanism in various dimensions including frame, channel and spatial ones into the MEF task so as to bring us significant quality improvement over the state-of-the-art (SOTA). In addition, we collect a new MEF dataset consisting of 960 samples, 155 of which are manually tuned by professionals as ground-truth for evaluation. Our network is trained by this dataset in an unsupervised manner. Extensive experiments are conducted to demonstrate the effectiveness of all the newly proposed components, and results show that our approach outperforms the SOTA in our and another representative dataset SICE, both qualitatively and quantitatively. Moreover, our 1D LUT approach takes less than 4ms to run a 4K image on a PC GPU. Given its high quality, efficiency and robustness, our method has been shipped into millions of Android mobiles across multiple brands world-wide. Code is available at: https://github.com/Hedlen/MEFLUT.

  • 6 authors
·
Sep 21, 2023

LUT Tensor Core: Lookup Table Enables Efficient Low-Bit LLM Inference Acceleration

As large language model (LLM) inference demands ever-greater resources, there is a rapid growing trend of using low-bit weights to shrink memory usage and boost inference efficiency. However, these low-bit LLMs introduce the need for mixed-precision matrix multiplication (mpGEMM), which is a crucial yet under-explored operation that involves multiplying lower-precision weights with higher-precision activations. Unfortunately, current hardware does not natively support mpGEMM, resulting in indirect and inefficient dequantization-based implementations. To address the mpGEMM requirements in low-bit LLMs, we explored the lookup table (LUT)-based approach for mpGEMM. However, a conventional LUT implementation falls short of its potential. To fully harness the power of LUT-based mpGEMM, we introduce LUT Tensor Core, a software-hardware co-design optimized for low-bit LLM inference. Specifically, we introduce software-based operator fusion and table symmetrization techniques to optimize table precompute and table storage, respectively. Then, LUT Tensor Core proposes the hardware design featuring an elongated tiling shape design to enhance table reuse and a bit-serial design to support various precision combinations in mpGEMM. Moreover, we design an end-to-end compilation stack with new instructions for LUT-based mpGEMM, enabling efficient LLM compilation and optimizations. The evaluation on low-bit LLMs (e.g., BitNet, LLAMA) shows that LUT Tensor Core achieves more than a magnitude of improvements on both compute density and energy efficiency.

  • 11 authors
·
Aug 12, 2024

Echo-DND: A dual noise diffusion model for robust and precise left ventricle segmentation in echocardiography

Recent advancements in diffusion probabilistic models (DPMs) have revolutionized image processing, demonstrating significant potential in medical applications. Accurate segmentation of the left ventricle (LV) in echocardiograms is crucial for diagnostic procedures and necessary treatments. However, ultrasound images are notoriously noisy with low contrast and ambiguous LV boundaries, thereby complicating the segmentation process. To address these challenges, this paper introduces Echo-DND, a novel dual-noise diffusion model specifically designed for this task. Echo-DND leverages a unique combination of Gaussian and Bernoulli noises. It also incorporates a multi-scale fusion conditioning module to improve segmentation precision. Furthermore, it utilizes spatial coherence calibration to maintain spatial integrity in segmentation masks. The model's performance was rigorously validated on the CAMUS and EchoNet-Dynamic datasets. Extensive evaluations demonstrate that the proposed framework outperforms existing SOTA models. It achieves high Dice scores of 0.962 and 0.939 on these datasets, respectively. The proposed Echo-DND model establishes a new standard in echocardiogram segmentation, and its architecture holds promise for broader applicability in other medical imaging tasks, potentially improving diagnostic accuracy across various medical domains. Project page: https://abdur75648.github.io/Echo-DND

  • 4 authors
·
Jun 18, 2025

Anatomy-Guided Residual Motion Diffusion for Controllable 4D Cardiac MRI Synthesis

Developing robust artificial intelligence models for 4D (3D + time) medical imaging is constrained by limited annotated data, inter-device domain shifts, and privacy restrictions. To address this, we propose a 4D controllable generative framework for anatomically consistent data augmentation. A semi-supervised variational autoencoder learns a compact latent representation of anatomical volumes while jointly predicting aligned segmentation masks in a unified framework. Anatomical structure is then disentangled from temporal dynamics through a cascaded latent diffusion model (LDM). A static LDM generates subject-specific anatomy conditioned on clinical priors (diagnosis and volumes measures) and a subsequent motion LDM estimates residual latent motions, ensuring strict temporal coherence across the 4D sequence. The proposed approach was evaluated on cine cardiac MRI as a representative 4D imaging application. Experiments across multiple datasets demonstrate high controllability of static anatomy (Pearson r > 0.8) and strong temporal coherence (FVD = 288.08). In cross-vendor generalization experiments, augmenting training sets with synthetic 4D sequences significantly improves downstream segmentation performance. Using nnU-Net, the proposed augmentation strategy improves the average Dice score by 1.4% and reduces the Hausdorff Distance by 3.0mm compared to training on real data alone, for the left ventricle, Dice improves by 2.8% with a 5.4mm reduction in boundary error. Overall, this framework provides a scalable and controllable solution for 4D medical image synthesis, supporting the development of more robust models with limited annotations and cross-vendor variability. Code available on https://github.com/cyiheng/4DCardiacMRISynthesis.

  • 5 authors
·
Jun 24

Instella-T2I: Pushing the Limits of 1D Discrete Latent Space Image Generation

Image tokenization plays a critical role in reducing the computational demands of modeling high-resolution images, significantly improving the efficiency of image and multimodal understanding and generation. Recent advances in 1D latent spaces have reduced the number of tokens required by eliminating the need for a 2D grid structure. In this paper, we further advance compact discrete image representation by introducing 1D binary image latents. By representing each image as a sequence of binary vectors, rather than using traditional one-hot codebook tokens, our approach preserves high-resolution details while maintaining the compactness of 1D latents. To the best of our knowledge, our text-to-image models are the first to achieve competitive performance in both diffusion and auto-regressive generation using just 128 discrete tokens for images up to 1024x1024, demonstrating up to a 32-fold reduction in token numbers compared to standard VQ-VAEs. The proposed 1D binary latent space, coupled with simple model architectures, achieves marked improvements in speed training and inference speed. Our text-to-image models allow for a global batch size of 4096 on a single GPU node with 8 AMD MI300X GPUs, and the training can be completed within 200 GPU days. Our models achieve competitive performance compared to modern image generation models without any in-house private training data or post-training refinements, offering a scalable and efficient alternative to conventional tokenization methods.

  • 10 authors
·
Jun 26, 2025

FunduSegmenter: Leveraging the RETFound Foundation Model for Joint Optic Disc and Optic Cup Segmentation in Retinal Fundus Images

Purpose: This study introduces the first adaptation of RETFound for joint optic disc (OD) and optic cup (OC) segmentation. RETFound is a well-known foundation model developed for fundus camera and optical coherence tomography images, which has shown promising performance in disease diagnosis. Methods: We propose FunduSegmenter, a model integrating a series of novel modules with RETFound, including a Pre-adapter, a Decoder, a Post-adapter, skip connections with Convolutional Block Attention Module and a Vision Transformer block adapter. The model is evaluated on a proprietary dataset, GoDARTS, and four public datasets, IDRiD, Drishti-GS, RIM-ONE-r3, and REFUGE, through internal verification, external verification and domain generalization experiments. Results: An average Dice similarity coefficient of 90.51% was achieved in internal verification, which outperformed all baselines, some substantially (nnU-Net: 82.91%; DUNet: 89.17%; TransUNet: 87.91%). In all external verification experiments, the average results were about 3% higher than those of the best baseline, and our model was also competitive in domain generalization. Conclusions: This study explored the potential of the latent general representations learned by RETFound for OD and OC segmentation in fundus camera images. Our FunduSegmenter generally outperformed state-of-the-art baseline methods. The proposed modules are general and can be extended to fine-tuning other foundation models. Translational Relevance: The model shows strong stability and generalization on both in-distribution and out-of-distribution data, providing stable OD and OC segmentation. This is an essential step for many automated tasks, from setting the accurate retinal coordinate to biomarker discovery. The code and trained weights are available at: https://github.com/JusticeZzy/FunduSegmenter.

  • 3 authors
·
Apr 22